Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Emmanuel Mfitundinda
ID: UNCST-2024-R015971
 Surveillance for recurrence and residual cervical intraepithelial neoplasia using high-risk human papillomavirus testing at Kawempe National Referral Hospital in Uganda, 2025
REFNo: HS5795ES

To improve surveillance for residual and recurrent CIN during follow up of women attending Kawempe National Referral Hospital (KNRH) in Uganda Specific objectives (i) To determine the prevalence of hr-HPV among women with CIN and those without CIN at Kawempe NRH, January-November, 2025 (ii) Determine the diagnostic/prediction accuracy of hr-HPV compared to the standard cytology for residual or recurrent CIN of any grade. (iii) Determine factors associated with progression of any CIN to a higher grade CIN or invasive cervical carcinoma (iv) Assess the level of acceptance of hr-HPV screening in women treated for CIN among health workers in the women's clinic at Kawempe National Referral Hospital
Uganda 2025-08-26 16:02:41 2028-08-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Pamella Abwoyo
ID: UNCST-2024-R015875
 Prevalence And Associated Factors Of Extended-Spectrum Beta-Lactamase-Producing Escherichia Coli In Wet Markets In Lira District, Uganda: A One-Health Cross Sectional Study
REFNo: SS3917ES

1. To determine the prevalence and associated factors of ESBL-E.coli in chicken sold in wet markets in Lira District 2. To determine the prevalence and associated factors of ESBL-E.coli in wastewater sources in wet markets in Lira District 3. To determine the prevalence and associated factors of ESBL-E.coli in humans (chicken traders) in wet markets in Lira District
 Uganda 2025-08-26 16:01:07 2028-08-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
David Oguttu Were
ID: UNCST-2024-R005275
 Onchocerciasis infection status in patients with Nodding Syndrome and epilepsy in Madi-Mid North focus, Uganda
REFNo: HS6224ES

To determine the prevalence of Onchocerca volvulus infection in people with a history of Nodding Syndrome in Madi-Mid North, Uganda
 Uganda 2025-08-26 15:55:47 2028-08-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jonathan Kitonsa
ID: UNCST-2025-R018208
 Investigating metabolic outcomes in African adults living with HIV after switching to injectable antiretroviral therapy
REFNo: HS6320ES

1. a) To compare changes in weight, body mass index, lipid profiles, and blood pressure, over one and two years among patients receiving 2-monthly long-acting cabotegravir and rilpivirine and compare this with those remaining on oral ART. b) To determine factors associated with changes in weight, BMI, lipid profiles, and blood pressure over the one- and two-year periods. 2. To describe the baseline glycaemic status of an African population with a history of suboptimal HIV control, and the change in HbA1c whilst on long acting cabotegravir and rilpivirine compared with patients remaining on oral dolutegravir - based ART through one and two years of follow-up. 3. To compare change in 10-year cardiovascular risk among patients on long acting cabotegravir and rilpivirine with those remaining on oral dolutegravir - based ART after one and two years of follow-up. 4. To quantify the impact of tenofovir disoproxil fumarate cessation on estimated glomerular filtration rate across one and two years of follow-up among patients receiving 2-monthly long-acting cabotegravir and rilpivirine compared with those remaining on oral ART. 5. To compare serum leptin and fasting insulin levels during follow-up in a subset of participants with significant weight gain and sample of similar participants without weight gain at 12 months.
Uganda 2025-08-26 15:48:19 2028-08-26 Medical and Health Sciences Non-Clinical Trial Degree Award
VIVIAN ARINAITWE
ID: UNCST-2024-R016282
 Developing a Feasibility Framework for MedTech in Low-Resource Settings: A Case Study of the NeoNest Device in Mbarara District, Uganda
REFNo: SIR537ES

1.4.1. Main Objective
To evaluate the feasibility of implementing the NeoNest neonatal transport incubator in selected health facilities in Mbarara District, Uganda, and to develop a structured, context-specific feasibility assessment framework for introducing medical technologies in low-resource settings.
1.4.2. Specific Objectives
To assess current neonatal transport and thermal care practices in health facilities in Mbarara District.
To evaluate the simulated performance, usability, and acceptability of the NeoNest device in a controlled setting.
To identify barriers and enablers for the adoption and scale-up of the NeoNest device.
To develop and validate a feasibility assessment framework for medical technology deployment in low-resource settings, using expert consensus (e.g., Delphi ? 80% agreement).

 Uganda 2025-08-26 15:46:45 2028-08-26 Engineering and Technology Non-Clinical Trial Non-degree Award
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