Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Daniel Oeksnebjerg Bilyeli
ID:
"An Assessment Of Entomological Diversity And The Effect Of Organic Coffee Farming On Biodiversity In South Western Uganda Along A National Park Gradient. "
REFNo: NS64ES

We will go to Bwindi Forest Farm in Uganda to investigate the effects on agro- organic farming. This will be done to analyse what best ways to conserve nature amidst a growing population taking up more space for settlement and agriculture. Here we will look at how effective organic coffee farming is compared to conventional farming in terms of biodiversity seen, incorporation of pollinators and the reduction of coffee's worst enemy, the coffee borer beetle. In this case you will help to support a project where data is collected about renewal of conventional farming into a more agro-organic approach. Project 1 - One of our goals is to investigate how well it is to practice organic farming in relation to conventional agriculture as regards to what supports biodiversity best. In relation to this, we will do some specific studies on the entomologi around organic and conventional coffee plantations as coffee has a huge economic and cultural significance worldwide. This will be done during the dry season running from september till November and during part of the rainy season running from November til Denmark . Project 2 - In this project, we look at one of the coffee plant's biggest enemies, Coffee Borer Beetle, which is a pest that drills into coffee beans and lays eggs in it. These beetles have some enemies, which are parasitoid wasps that naturally fight these pests. Here we will examine whether organic or conventional coffee cultivation is most effective in the natural control of these pests, and in this context where the greatest biodiversity of these wasps occurs. The collection of coffee berries will be done 10 times from 30 different coffee plants on an number of conventional and organic farms. This will be done during harvest season of ripe coffee berries in October and as well when the immature green berries show up to see if there are seasonal differences in pest presence. Project 3 - In addition, we will look at the effect of organically grown coffee on pollinators of the plant, such as bees, and the conditions that best benefit them. This is done as the number of pollinators worldwide is in decrease, which is a huge problem since pollination-dependent crops, such as the coffee plant, contribute 35 percent of the global crop production volume. This can have a huge impact on the yield and quality of the product, depending on whether it is an organic or conventional farm. This follows the same timeline as project 1.
 Denmark 2018-09-24 2021-09-24 Natural Sciences Degree Award
Soeren Christensen Krath
ID:
An Assessment Of Entomological Diversity And The Effect of Organic Coffee Farming on Biodiversity In South Western Uganda Along A National Park Gradient
REFNo: NS66ES

We will go to Bwindi Forest Farm in Uganda to investigate the effects on agroorganic farming. This will be done to analyse what best ways to conserve nature amidst a growing population taking up more space for settlement and agriculture. Here we will look at how effective organic coffee farming is compared to conventional farming in terms of biodiversity seen, incorporation of pollinators and the reduction of coffee's worst enemy, the coffee borer beetle. In this case you will help to support a project where data is collected about renewal of conventional farming into a more agroorganic approach. Project 1 One of our goals is to investigate how well it is to practice organic farming in relation to conventional agriculture as regards to what supports biodiversity best. In relation to this, we will do some specific studies on the entomologi around organic and conventionel coffee plantations as coffee has a huge economic and cultural significance worldwide. This will be done during the dry season running from september till November and during the rainy season running from November til December. Project 2 In this project, we look at one of the coffee plant's biggest enemies, Coffee Borer Beetle, which is a pest that drills into coffee beans and lays eggs in it. These beetles have some enemies, which are parasitoid wasps that naturally fight these pests. Here we will examine whether organic or conventional coffee cultivation is most effective in the natural control of these pests, and in this context where the greatest biodiversity of these wasps occurs. The collection of coffee berries will be done 30 different coffee plants on different conventional and organic farms. This will be done during harvest season of ripe coffee berries in October and as well when the immature green berries show up to see if there are seasonal differences in pest presence. Project 3 In addition, we will look at the effect of organically grown coffee on pollinators of the plant, such as bees, and the conditions that best benefit them. This is done as the number of pollinators worldwide is in decrease, which is a huge problem since pollinationdependent crops, such as the coffee plant, contribute 35 percent of the global crop production volume. This can have a huge impact on the yield and quality of the product, depending on whether it is an organic or conventional farm. This follows the same timeline as project 1.
 Denmark 2018-09-24 2021-09-24 Natural Sciences Degree Award
Adeodata Rukyalekere Kekitiinwa
ID: UNCST-2019-R000799
 Host Genetic Factors in Pediatric HIV/TB Infections II
REFNo: HS236ES

The cohort development core project of CAfGEN has several unique and innovative features. 1. This project will significantly expand what is currently the largest genomic cohort dedicated to pediatric HIV in Africa. 2. We will prospectively identify and recruit a cohort of HIV-positive, isoniazid naïve children with a strong exposure to TB, but without evidence of active TB disease – such TB resistant individuals are unique and highly desired in the field, even more so among children co-infected with HIV. This approach is highly conducive to high-level genetic mapping and thus has the potential to offer novel molecular insights into the development of active TB disease. 3. The current studies propose the expansion of our genomics studies to Swaziland – a Southern African population that is currently not represented on the African genomics map. This creates long-term opportunities to fulfill the stated desire to make the H3Africa initiative truly pan-African in scope. 4. The network will develop and extend the experience gained and lessons learned in implementing and pursuing genomics education and ethics consultation in furtherance of the mandate of engaging communities in genomics studies, which is key to long-term sustainability.
Uganda 2018-09-24 2021-09-24 Medical and Health Sciences Non-degree Award
Maruthi Sridhar Balaji Bhaskar
ID:
Geospatial Informatics for Environmental and Natural Resource Management
REFNo: PS5ES

Goals and Objectives: The goal of the proposed project is to identify the impact of long-term landscape and environmental changes on the water quality of Lake Victoria. Long-term, continuous remote sensing monitoring data will be utilized to quantify and assess the pigment and nutrient distribution in the waters of Lake Victoria. We hypothesize that the variations in pigment and nutrient concentrations will affect the intensity and spectral characteristics of the water and these relevant spectral signatures can be identified and mapped using satellite remote sensing. The specific objectives are to: 1) Analyze and map the spatial and temporal trends in the water quality characteristics of the Lake Victoria; 2) Identify the best water quality indicators for satellite monitoring of the environmental and ecological changes and 3) Monitor and propose remedial measures for the geographical regions within the Lake which are more vulnerable for the environmental and climate changes.
USA 2018-09-20 2021-09-20 Natural Sciences Non-degree Award
Bosco Bwambale
ID:
Flood risk management under climate and demographic change in Uganda: Evidence from the Nyamwamba
REFNo: A36ES

The study will be guided by three broad objectives: (1) analysis of the factors influencing the severity of flood disasters, (2) identification of flood risk reduction Measures, and (3) determining the most feasible flood risk reduction options for the Rwenzori
 Uganda 2018-09-20 2021-09-20 Agricultural Sciences Degree Award
Alex  Muganzi Muganga
ID: UNCST-2019-R000710
 Analysis of Routinely Collected Clinical Data to Monitor and Evaluate outcomes of the IDI Kampala-Wakiso region HIV program
REFNo: HS241ES

Primary objective: To describe the entire HIV cascade of care based on the UNAIDS 90:90:90 targets and outcomes of programmatic operational interventions Secondary Objective 1. To characterize the HTC and eMTCT programs and describe their outcomes e.g. lost to follow-up, seroconversion in previously negative mother-baby pairs etc. 2. To characterize the clinical profile of patients enrolled into care, including clinical laboratory indices – CD4, viral load, history of OIs – TB prophylaxis & treatment, ART history; describe their clinical outcomes including poor patient outcomes (drug toxicity, poor adherence, resistance, attrition, IRIS events) 3. To describe uptake of routinely provided prevention strategies, for example: Male medical circumcision (MMC), Prior ART (PrEP, PEP), self-testing; family planning services, sexual behavior risk patterns; (Abstinence, Fidelity, condom use) and their outcomes, e.g. STI’s, new HIV infections, OI’s 4. To describe the quality of routinely collected data - the extent and nature of missing data including data on WHO-UNAIDS required metrics, and accuracy of the electronic record compared to hand-written files 5. To determine the proportion of patients who undergo switching (single drug versus multiple drug), describe the processes of switching and their outcomes (single drug vs multiple drug or regimen switching) or other consequences of regimen adjustments. 6. To describe factors associated with and outcomes of routine approaches to reduce loss to follow up in HIV care of clients who miss appointments or are lost to follow up. 7. To describe the quality, feasibility (including cost-effectiveness) and outcomes of differentiated service delivery strategies (DSS) that are routinely implemented at IDI-supported facilities 8. To describe HIV/TB policy-practice gaps, and routine program strategies used to close these gaps and their outcomes
Uganda 2018-09-18 2021-09-18 Medical and Health Sciences Non-degree Award
Guy Schofield
ID:
Understanding the Ethical Challenges in the Practice of Palliative Care in Uganda
REFNo: SS219ES

Aim: To explore and describe the ethical challenges faced by palliative care professionals in Uganda, and assess clinical and educational implications Objectives: 1) To describe the range of ethical challenges faced by palliative care professionals in Uganda. 2) To explore the normative concepts contained within these challenges. 3) To investigate how these concepts might differ in content across different sub- Saharan Africa countries. 4) To consider the implications of these findings for palliative care professionals and educators in sub-Saharan Africa and worldwide, including the UK. This application relates to objectives 1 & 2.
UK 2018-09-14 2021-09-14 Social Science and Humanities Degree Award
Moses Arinaitwe
ID:
UGANDA HEALTH LABOUR MARKET ANALYSIS
REFNo: SS237ES

The purpose of this study is to conduct a labor market analysis of the Ugandan health workforce so as to inform future human resources for health policies, plans, and legal frameworks. SO 1: Analyze the current and future health landscapes, taking into account epidemiological and population changes and national and international health commitments/strategies. SO 2: Assess the health workforce supply against national health care market needs SO 3: Assess the current demand for the health workforce (# of positions/vacancies) alongside an analysis of trends over the past 5 years in deployment, distribution, wage, current and emerging cadres, type of employer, motivation (incentives and fringe benefits) in-country and within the East African region SO 4: Make projections for demand and supply for HRH for the next 20 years giving at least two different scenarios SO 5: Analyze the roles and responsibilities of key players and their influence on the labor market SO 6: Assess the impacts of key government policies, laws, regulations and reforms on the health labor market
Uganda 2018-09-14 2021-09-14 Social Science and Humanities Non-degree Award
Johnblack Kabukye Kabaalu
ID: UNCST-2019-R001109
 Assessment of Organizational readiness to Implement Electronic Health Record Systems in Oncology in Low resource settings: A case study of the Uganda Cancer Institute
REFNo: IS14ES

1. To assess the level of organizational readiness of the Uganda Cancer Institute to implement an EHR as perceived by the staff 2. To determine which factors contribute to this readiness perception.
 Uganda 2018-09-14 2021-09-14 Social Science and Humanities Degree Award
Nadine Sanchez
ID:
Addressing Cultural and Practical Barriers to Epilepsy Care in Uganda
REFNo: HS108ES

The main objective of this study is to identify cultural and practical challenges of seeking epilepsy care in Uganda. Outcomes from this study can inform specific targets of future interventions, and is imperative for working towards improving the provision of epilepsy care.
 USA 2018-09-13 2021-09-13 Medical and Health Sciences Degree Award
AGNES NAGGIRINYA BWANIKA
ID: UNCST-2019-R001126
 Experiences and outcomes of people living with HIV receiving mobile phone baed adherence support
REFNo: HS149ES

Primary objective: To investigate the experiences of PLHIV receiving mobile phone based adherence support Secondary objectives: To evaluate the clinical and virological outcomes in patients receiving adherence support for anti-retroviral treatment To evaluate the interaction and attitudes of patients and health care workers with a mobile phone based adherence tool
Uganda 2018-09-13 2021-09-13 Medical and Health Sciences Non-degree Award
Martha Muhwezi Lunyolo Rose
ID:
The Role of Technical and Vocational Education and Training in Women Empowerment in Uganda
REFNo: SS221ES

i. To examine the contribution of TVET and the opportunities for women’s empowerment through TVET in Uganda. ii. To examine the impact of TVET Training on employability of Women graduates in Uganda. iii. To determine the knowledge, attitudes, infrastructure, curriculum and practice about TVET from the current students in TVET institutions in Uganda.
Uganda 2018-09-13 2021-09-13 Social Science and Humanities Degree Award
Freddy Kitutu Eric
ID: UNCST-2020-R014751
 Pharmacovigilance awareness, practices and its determinants among sexual and reproductive health care providers and care-seekers in Uganda
REFNo: HS135ES

1. To explore awareness of the process of reporting ADRs to the National Pharmacovigilance Centre among health care professionals at surveyed sexual and reproductive health clinics 2. To determine the extent of suspected ADR detection among health care professionals at surveyed sexual and reproductive health clinics 3. To assess the level of knowledge of the ADR reporting system in Uganda among health care professionals at surveyed sexual and reproductive health clinics 4. To establish the attitudes towards suspected ADR reporting among health care professionals at surveyed sexual and reproductive health clinics 5. To explore the care-seeker (patients and clients) experiences that shape perceptions of suspected adverse events at the surveyed sexual and reproductive health clinics
Uganda 2018-09-06 2021-09-06 Medical and Health Sciences Non-degree Award
Abel Atukwase
ID:
Assessment of Aflatoxin Exposure among Peri-urban Low Income populations in Kampala Capital City
REFNo: HS202ES

i.To assess the determinants of aflatoxin exposure among children (6-59 months) and mothers of reproductive age (15-49 years) ii.To estimate aflatoxin exposure among children (6-59 months) and mothers of reproductive age (15-49 years) iii.Assess the relationship between aflatoxin exposure an nutritional status of children (6-59 months) iv.To design and disseminate aflatoxin Information, Education and Communication materials for improving awareness on the effects of aflatoxins among the low income populations living in peri-urban areas of Kampala Capital City.
Uganda 2018-09-06 2021-09-06 Medical and Health Sciences Non-degree Award
Anne Christianson
ID:
Examining ecosystem-based approaches to climate change adaptation: the intersection of gender capabilities and biodiversity conservation
REFNo: NS61ES

This research seeks to examine the impact of ecosystem-based adaptation programs, namely the Global Mountain EbA Programme (the Mountain Programme) on the climate resilience of individuals. There will be a particular focus on women within communities where these programs have been implemented. Working alongside partners at the International Union for Conservation of Nature (IUCN), the United Nations Development Programme (UNDP), and The Mountain Institute (TMI), this interdisciplinary research project explores the intersection between human adaptation measures and biodiversity conservation. These issues will be examined through the application of the capabilities approach and resilience framework to focus groups, community interviews, and expert interviews undertaken in resource-dependent communities near Mount Elgon National Park, Uganda. Results of this research will directly inform future global adaptation program governance and contribute significantly to the human development and climate change adaptation literature.
 USA 2018-09-06 2021-09-06 Natural Sciences Degree Award
Wan Zhu Zhang
ID:
Detecting and treating subclinical anthrathycline therapy related cardiac dysfunction in low income country
REFNo: HS220ES

The objective of this research is to describe the burden of subclinical ATRCD by applying international guideline on Uganda cancer patient and to evaluate the significance of treating subclinical ATRCD with carvedilol. Specific objectives: 1. To determine the incidence of subclinical ATRCD among cancer patient who receives Anthracycline therapy. 2. To compare the changes of GLS value between hypertension and non hypertension cancer patient at the completion of the anthracycline therapy. 3. To determine the correlation of conventional ECHO parameters (MAPSE, S’) with GLS, and their ability to diagnose or rule out subclinical ATRCD. 4. To determine the correlation of oxidative stress with cardiac function(GLS value) in patients who receives Anthracycline therapy 5. To describe the cardioprotective effect of carvedilol in patients with subclinical ATRCD.
Uganda 2018-09-06 2021-09-06 Medical and Health Sciences Degree Award
Rosalind  Parkes-Ratanshi Parkes
ID: UNCST-2019-R000717
 DEVELOPMENT OF THE ART ACCESS APPLICATION
REFNo: HS230ES

General objective: To document the process involved in the development of the ART Access Application for health in a resource limited setting. Specific objectives More specifically, the study seeks to: 1) To understand the consequences of interactions between different developers and the end users through observation 2) Develop further qualitative and quantitative data collection tools to evaluate the use and outcomes of the ART Access Application.
UK 2018-09-06 2021-09-06 Medical and Health Sciences Non-degree Award
Adeodata Rukyalekere Kekitiinwa
ID: UNCST-2019-R000799
 End of Project Evaluation for the Baylor Uganda SNAPS WEST Project
REFNo: HS227ES

Evaluation goal The goal of the evaluation is to establish the impact of SNAPS WEST project on HIV service delivery in the Rwenzori region. Evaluation Objectives General objective The general objective is to conduct an end of project evaluation to assess the extent to which the project has met the objectives as stated in the Funding Opportunity Announcement that led to this award. Specific objectives 1) To determine the extent to which “Strengthening National Paediatric HIV/AIDS and Scaling up Comprehensive HIV/AIDS Services in the Republic of Uganda under The President’s Emergency Plan For AIDS Relief project”: i. Scaled up access to paediatrics and adolescent HIV/AIDS/TB care and treatment at COE between 2012 and 2018 ii. Scaled up access to comprehensive HIV care and treatment services in the 7 districts of Rwenzori region between 2012 and 2018. iii. Supported MoH and its partners in a) Strengthening National Paediatric/Adolescent HIV/AIDS Care , b) providing training, mentorship and technical support supervision to RRHs and lower health facilities providing HIV care and ART services, c) providing expert consultation to health workers through the national paediatric and adolescent call centre. iv. Strengthened implementation of district based programming approach as well as support for integration of GHI principles into comprehensive HIV/AIDS care and treatment and other health services over the project period. 2) To assess the relevance of: i. The SNAPS WEST project strategies to the implementers (MOH, districts & Baylor Uganda Clinical Centre of Excellence staff) as well project challenges & recommendations for HIV programing in regard to HTC, PMTCT, Care and Treatment, SMC, OVCs, PP/KPs. ii. The SNAPS WEST project to; a) the HIV care needs of clients in the Rwenzori region and COE, b) as well as information needs for health workers using services of the national paediatric call centre. 3) Document project lessons learnt, challenges faced and make appropriate recommendations
Uganda 2018-08-31 2021-08-31 Medical and Health Sciences Non-degree Award
Justus Munywoki Mulinge
ID:
Comparative phylogeography of water lilies in Africa
REFNo: NS59ES

To map water lilies in the sampled countries To determine if there is phylogeographical pattern in the populations To determine the factors influencing their geographical distribution pattern
Kenya 2018-08-31 2021-08-31 Natural Sciences Degree Award
Ronnie Steinitz
ID: UNCST-2019-R000713
 Food Fights: Competition among fruit-eating primates in Kibale National Park, Uganda
REFNo: NS60ES

To determine whether between-species feeding competition is a significant energetic constraint for red-tailed monkeys – more so than for larger-bodied, competing primate species.
 USA 2018-08-31 2021-08-31 Natural Sciences Degree Award
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