Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
Search By Approval Date:
Clear Filter Total: 5,795
Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Isaac Ssewanyana
ID: UNCST-2020-R014336
ULTRA Covi-Catch Ag. Laymen Study including Usability. "Clinical Performance Study Plan - CPSP nr. BSS-CPH 22-054"
REFNo: HS2933ES

Part 3: Observed untrained user study o Evaluation of test results and interpretations when performed by laymen in a self-testing environment while being observed by healthcare providers. These observations will be captured using a questionnaire-based survey.,art 2: Results interpretation study o Reading and interpretation of 6 contrived devices by a minimum of 100 laypersons while being supervised by a neutral healthcare provider. The contrived devices should reflect the different ranges of reactivity: − non-reactive (x 1) − reactive (x 1) − weak reactive (x 2) − invalid (x 2).,Part 1: Labelling comprehension study o Questionnaire-based-survey to assess whether the key messages and instructions from packaging and labelling are understandable and easy to follow.,The objective of this laymen study is to establish the usability of the ULTRA Covi-Catch Ag in a self-testing environment. More specifically, the study will assess whether the instructions for use and labels are clear and understandable and whether the test can be performed correctly by laypersons.,
Uganda 2023-09-26 12:24:11 2026-09-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Phillip Ssekamatte
ID:
IMMUNOLOGICAL, METABOLIC AND GENE TRANSCRIPTIONAL CHANGES AMONG PATIENTS WITH TUBERCULOSIS AND TYPE 2 DIABETES MELLITUS IN UGANDA (IMG STUDY)
REFNo: HS2990ES

Sub-study 1: To evaluate the immunologic, metabolic, and genetic mechanisms of TB susceptibility in DM. Sub-study 2: To assess baseline differences in Mtb-specific CD4+ and CD8+ T cell functional phenotypes and memory frequencies among LTBI and ATB patients with and without T2DM. Sub-study 3: To determine the effect of TB preventive therapy using isoniazid therapy on the function and memory frequency of Mtb-specific CD4+ and CD8+ T cells among LTBI and ATB patients with and without T2DM. Sub-study 4: To profile baseline immune-metabolic changes among LTBI and ATB patients with and without T2DM. Sub-study 5: To investigate gene expression differences in the 6-gene transcriptome signature (TB RISK6; GBP2, SERPING1, FCGR1B, TRMT2A, SDR39U1, TUBGCP6) among LTBI and ATB patients with and without T2DM at baseline and 6 months of TB preventive therapy.
Uganda 2023-09-26 12:13:20 2026-09-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Ambaru  Ojia Jacinta
ID:
PREVALENCE OF SEPSIS, 30 DAY CASE FATALITY RATIO, AND OPTIMAL MORTALITY RISK SCORES AMONG POST-CHEMOTHERAPY CANCER PATIENTS WITH INFECTION AT ONCOLOGY CLINIC MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS3111ES

Aim 3. To determine the optimal mortality risk score to predict 30-day mortality for post cancer-chemotherapy patients with infection at oncology clinic Mbarara regional referral hospital,Aim 2. To determine the 30-day case fatality ratio for post-cancer chemotherapy patients with infection at oncology clinic Mbarara regional referral hospital ,Aim 1: To determine the point prevalence of sepsis in post-cancer chemotherapy patients with infection, according to mortality risk scores (qSOFA, UVA, SIRS), at Mbarara regional referral hospital ,To determine the prevalence of sepsis, 30-day case fatality ratio and optimal mortality risk score, among patients with post-cancer chemotherapy infection at oncology clinic MRRH,
Uganda 2023-09-26 12:11:47 2026-09-26 Medical and Health Sciences Non-Clinical Trial Degree Award
MARTIN CHEBET
ID: UNCST-2021-R013905
THE INCIDENCE AND AETIOLOGY OF STILLBIRTHS IN EASTERN UGANDA
REFNo: HS3112ES

3. To assess the acceptability of minimal invasive autopsy in Eastern Uganda,2. To determine the infections associated with stillbirths in a regional referral hospital in eastern Uganda,1. To determine the incidence of and risk factors for stillbirths in a cluster-randomised trial cohort of pregnant women (the BabyGel trial) ,
Uganda 2023-09-26 12:04:01 2026-09-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Hellen Tabea
ID:
THE EXPERIENCE OF CONSECRATED PERSONS ON GRIEF AND COPING UPON THE LOSS OF A /RELIGIOUS/FAMILY MEMBER- UGANDA
REFNo: SS1927ES

To assess the religious and cultural factors influencing consecrated persons when faced with loss.,To find out how consecrated persons manage socio and economic factors to handle medical, psychological and moral issues in grief and loss.,To examine how consecrated member grief and mechanics of coping with loss of a member/family,To asses the experience of the consecrated persons in Uganda upon the less of a religious or family member.,
Uganda 2023-09-26 11:59:11 2026-09-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Florence Asiimwe Munyonyo
ID:
A Phenomenological Study of Lived Experiences of Returnee Ugandan Migrant Domestic Workers from Saudi Arabia
REFNo: SS1905ES

4. To inform policy reforms for regulating the sector to maximize the benefits for the development of all stakeholders.,3. To examine how the lived experiences affected the realization of the goals for seeking employment in Saudi Arabia. ,2. To evaluate the lived experiences of returnee Ugandan migrant domestic workers before, during and when they return from Saudi Arabia. ,To examine the push and pull factors why returnee Ugandan migrant domestic workers seek employment in Saudi Arabia,
Uganda 2023-09-26 11:56:57 2026-09-26 Social Science and Humanities Non-Clinical Trial Degree Award
Adoke Yeka
ID: UNCST-2021-R004300
PLATINUM: A multi-part, multi-center PLATform study to assess the efficacy, safety, tolerability and pharmacokinetics of anti-malarial agents administered as monotherapy at multiple dose levels and/or combination therapy IN patients with Uncomplicated Plasmodium falciparum Malaria.
REFNo: HS2817ES

Part A: To assess the parasite clearance time (PCT) of oral doses of an anti- malarial agent administered as monotherapy in patients with uncomplicated
P. falciparum malaria
Part B: To assess the effect on adjusted 28-day cure rate of an anti-malarial agent administered orally as combination therapy versus the standard of care (SoC) in patients with uncomplicated P. falciparum malaria.
Part A: To assess the effect on adjusted 28-day cure rate of an anti-malarial agent administered orally as monotherapy in patients with uncomplicated
P. falciparum malaria
Part B: To assess the parasite clearance time (PCT) of oral combinations of anti-malarial agents versus SoC in patients with uncomplicated P. falciparum malaria
All parts:
To characterize PK of each anti-malarial agent administered orally as monotherapy [Part A] and/or as combination therapy [Part B] in patients with uncomplicated P. falciparum malaria
To assess the safety and tolerability of each anti-malarial agent administered orally as monotherapy [Part A] and/or as combination therapy versus SoC [Part B] in patients with uncomplicated P. falciparum malaria


Uganda 2023-09-26 11:55:15 2026-09-26 Medical and Health Sciences Clinical Trial Non-degree Award
Christine Kyarituha Arinaitwe
ID:
Determinants of nutrition outcomes of adolescent girls in Rukiga District.
REFNo: NS507ES

General Objective
To assess the determinants of nutrition outcomes of adolescent girls aged 10-14 years in Primary School in Rukiga district, Western Uganda.
Specific Objectives
1.To assess the nutritional status among adolescent girls aged 10-14 Years, Rukiga District.
2.To assess the diet quality with emphasis on Iron-rich foods consumed by adolescent girls aged 10-14 years in Rukiga district.
3.Assess the dietary knowledge among adolescent girls aged 10-14 years in Rukiga District.
4.Establish the relationship between the nutrition status and nutritional , morbidity ,lack of breakfast and snacking among adolescent girls aged 10-14 years in
Rukiga District
5.Assess the perceptions of community members regarding the diet of adolescent girls in Rukiga District.

Uganda 2023-09-26 11:06:52 2026-09-26 Natural Sciences Non-Clinical Trial Degree Award
Eve  Namisango
ID: UNCST-2021-R014038
Piloting a measure of gender competency among family planning providers
REFNo: SS1567ES

The overall goal of the study is to pilot test a survey instrument that measures gender competency among family planning providers. ,
Uganda 2023-09-26 10:58:18 2026-09-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Judith Nalukwago
ID:
Uganda Social and Behavior Change Project Assessment
REFNo: SS1350ES

General objective
The general objective of the assessment is to contribute to the ongoing update for the estimates of key programmatic and performance indicators so as to get an understanding of impact and sustainability of the SBCA intervention.
Specific objectives
To provide evidence to inform the design, implementation, and evaluation of project specific social and behaviour change (SBC) interventions.
To determine the status of key project indicators.

Uganda 2023-09-26 10:57:03 2026-09-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
View Sort By:

"A prosperous Science and Technology Led Ugandan Society."