Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Russell Morton
ID: UNCST-2026-R024044
Born Safe or Made Safe? The Role of Market Organization in Uganda's Informal Transit Sector
REFNo: SS5155ES

Main Objective 1. To examines how market organization affects safety provision in Uganda\'s informal motorcycle taxi (boda boda) sector. 2. To evaluate the feasibility of experimental design and data collection procedures. 3. To measure stage selection of drivers by analyzing how stage managers\' rankings of potential entrants correlate with driver safety characteristics 4. To Estimate driver self-selection into organized boda stages by measuring the relationship between baseline driving behavior and drivers\' willingness to join stages 5. To Estimate the causal treatment effect of stage membership on driving behavior using randomized subsidies for stage entry fees Specific Objectives 1. Our specific objectives of this program include learning about the safety of boda drivers, how stages affect boda driver behaviors, how boda drivers of different safety sort into joining stages or working as lubyanza drivers, and how passengers think about boda safety and associated implications for incentives for drivers to behave safely. We also analyze how stage organization and behaviors are related to safety at the stage
United States of America 2026-05-28 15:05:57 2029-05-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
Damari Atusasiire
ID: UNCST-2024-R002645
Evaluation of the Building Tomorrow NRD Program in Uganda
REFNo: SS5321ES

The primary objective of this study is to assess changes in learners’ numeracy scores and determine the extent to which these changes can be attributed to the BT NRD intervention. ,
Uganda 2026-05-28 15:03:18 2029-05-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
Davies Otieno
ID: UNCST-2025-R021802
Development of a maternal sepsis model using a physiologically based pharmacokinetic approach
REFNo: HS7463ES


Kenya 2026-05-28 15:00:25 2029-05-28 Medical and Health Sciences Non-Clinical Trial Degree Award
GASTONE HABARUGABA
ID: UNCST-2025-R017858
CLIMATE VARIABILITY AND SMALLHOLDER FARMER LIVELIHOODS IN THE MOUNTAIN AGRO ECOLOGICAL ZONE OF RUBANDA DISTRICT, WESTERN UGANDA.INTEGRATING SOCIO-ECOLOGICAL SYSTEMS APPROACH FOR MITIGATION
REFNo: NS1239ES

To analyse the trend of climate variability in Rubanda from 1993-2024 2-To examine smallholder farmers’ vulnerability to climate variability in Rubanda 3- To analyse the impact of climate variability on food security status of smallholder farmers in Rubanda 4- To assess the impact of climate variability on rural forest livelihoods of smallholder farmers in Rubanda 5- To ascertain sustainable socio-ecological climate variability adaptation approaches for agroecological balance in Rubanda
Uganda 2026-05-22 19:38:44 2029-05-22 Natural Sciences Degree Award
Henry Mugerwa
ID: UNCST-2019-R000420
A Phase I/II clinical study to investigate the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of ITU512 in healthy participants and patients with sickle cell disease
REFNo: HS6925ES

1.To assess the safety and tolerability
of ITU512 in healthy participants
2.To assess the safety and tolerability
of ITU512 in participants with SCD
3.To assess the effect of ITU512 on
fetal hemoglobin expression

Uganda 2026-05-22 16:52:18 2029-05-22 Medical and Health Sciences Clinical Trial Non-degree Award
Michael King
ID: UNCST-2026-R023619
Gender Focused Multi-Faceted Anti-Poverty Programs: Low-Cost Options for Scale-up
REFNo: SS5152ES

• To estimate the causal impact of adding a community-level gender empowerment intervention to the standard VE graduation programme on women’s agency, intra-household decision-making, and household economic outcomes. • To estimate the additional (marginal) impact of complementing community-level interventions with household-level couples training on the same outcomes. • To identify how gender-transformative interventions affect the process of intra-household decision-making by decomposing decisions into stages (initiation, discussion, agreement, implementation). • To assess whether observed changes in decision-making reflect improvements in women’s empowerment, household cooperation, or both. • To evaluate the effects of the interventions on household risk management, including both ex-ante preparation (e.g. savings, planning) and ex-post coping strategies (e.g. asset sales, borrowing). • To test a trauma-sensitive survey innovation in measuring intimate partner violence (IPV), specifically a “stop rule” approach, and assess its effects on respondent burden, survey fatigue, and data quality. • To assess the cost-effectiveness and scalability of gender-transformative additions to graduation-style programmes for policy and implementation contexts.
Ireland 2026-05-21 9:55:20 2029-05-21 Social Science and Humanities Non-Clinical Trial Non-degree Award
Vicent Rutagangibwa
ID: UNCST-2022-R010288
Exploring Variation in How Sustainability is Experienced in Ugandan Engineering Education: A Phenomenographic Study
REFNo: SIR636ES

The overall objective of this study is to examine how sustainability is conceived, formally represented, and experienced across institutional, curricular, and pedagogical dimensions within Ugandan engineering education, focusing on the views of both faculty and students. Specifically, the study seeks: (1) to determine the extent and ways sustainability is reflected in the institutional and curricular documents of MUST’s engineering programmes; (2) to explore the varied ways engineering students at MUST conceive and experience sustainability in their education; and (3) to explore the varied ways engineering faculty at MUST conceive sustainability and integrate it into their teaching and learning activities.
Uganda 2026-05-21 9:41:21 2029-05-21 Engineering and Technology Non-Clinical Trial Degree Award
Silver Onyango
ID: UNCST-2022-R009337
A PILOT STUDY ON USING LOW-COST AIR QUALITY SENSORS TO INFLUENCE COOKING BEHAVIOR IN GREATER MASAKA REGION, UGANDA.
REFNo: HS7732ES

Evaluate the operation of air quality warning displays and participant response to their installation. ,Evaluate the performance of heat, motion, and location sensors in recording cooking behaviors in Masaka, Uganda. ,Evaluate the performance of low-cost PM and CO monitors in estimating air quality in kitchens in Masaka, Uganda.,i. Evaluate the performance of low-cost PM and CO monitors in estimating air quality in kitchens in Masaka, Uganda.,Evaluate the performance of low-cost air quality sensors, cooking behavior sensors, and feedback displays in Masaka, Uganda. ,
Uganda 2026-05-21 9:25:38 2029-05-21 Medical and Health Sciences Non-degree Award
Irene Amuron
ID: UNCST-2025-R020857
Understanding knowledge and perceptions of extreme heat on health in Gulu and Kisoro districts in Uganda
REFNo: HS7502ES

1. To examine how different populations in Gulu and Kisoro districts perceive extreme heat risk and to quantify the proportion of households that consider heat a significant risk 2. To identify who is most at risk from heat risk in Gulu and Kisoro districts and estimate the proportion of households affected by extreme heat. 3. To identify the health impacts of extreme heat risks among the population in Gulu and Kisoro districts. 4. To analyse the early warning and early action strategies that the communities in Gulu and Kisoro can access to and utilise.
Uganda 2026-05-21 21:22:57 2029-05-21 Medical and Health Sciences Non-Clinical Trial Degree Award
Lawrence Mugisha
ID:
Hyperplexed targeted assays powered by metagenomics towards cost effective and feasible solutions for public health Surveillance of Emerging pathogens based on wastewater Epidemiology – HySEEk
REFNo: NS1237ES

1) To discover and characterise novel febrile-illness causing pathogens in Uganda and evaluate wastewater-based epidemiology for surveillance and preparedness.
2) To validate state-of-the-art metagenomic approaches for the discovery of emerging pathogens in wastewater collected in low-income settings.
3) To evaluate multiple gold-standard and novel targeted molecular detection techniques to rapidly implement high-frequency monitoring of new pathogens through wastewater-based epidemiology

Uganda 2026-05-21 20:56:50 2029-05-21 Natural Sciences Non-Clinical Trial Non-degree Award
Hamidah Baseka
ID: UNCST-2025-R019915
RESOURCE AVAILABILITY AND MANAGEMENT OF EARLYCHILDHOOD DEVELOPMENT CENTERS IN WAKISO DISTRICT, UGANDA
REFNo: SS5041ES

The purpose is to investigate the relationship between resource availability and the management of early childhood development centers, in the Wakiso district in Uganda.

Specific Objectives
i. To assess the relationship between availability of human resources and management of early childhood development centers in Wakiso district in Uganda.
ii. To establish the relationship between financial resources and management of Early Childhood Development Centers in Wakiso district in Uganda.
iii. To determine the relationship between physical facilities and the management of Early Childhood Development Centers in Wakiso District, Uganda.
iv. To find out the relationship between the school plant and the management in Early Childhood Development Centers in Wakiso District, Uganda.
v. To assess the moderating role of headteachers’ management skills in the relationship between resource availability and the management of Early Childhood Development Centers in Wakiso District, Uganda.

Uganda 2026-05-20 18:57:39 2029-05-20 Social Science and Humanities Non-Clinical Trial Degree Award
BUKIRWA N GERMINA RESTY
ID: UNCST-2025-R020648
Corporate Culture and Organisational Sustainability in the Hotel Industry, Kampala Uganda
REFNo: SS5180ES

Purpose of the study The purpose of this study is to critically examine the effect of corporate culture on organizational sustainability within the hotel industry in Kampala, Uganda. Specifically, the study aims to explore how different dimensions of corporate culture influence the environmental, social, and economic pillars of sustainability in hotel enterprises. Specific objectives This study will be based on the following objectives; i) To examine the effect of core values on organizational sustainability in the hotel industry Kampala, Uganda. ii). To evaluate the effect of adaptability on organizational sustainability in the hotel industry Kampala, Uganda. iii).To identify the effect of leadership orientation on organizational sustainability in the hotel industry, Kampala, Uganda. iv).To investigate the moderating effect of employee engagement on corporate culture and organizational sustainability in the hotel industry, Kampala, Uganda.
Uganda 2026-05-20 18:31:49 2029-05-20 Social Science and Humanities Non-Clinical Trial Degree Award
Juliana Nanimambi
ID: UNCST-2022-R010812
EXPLORATION OF THE PERI-OPERATIVE CARE PATHWAY'S IMPACT ON POSTOPERATIVE OUTCOMES AFTER EMERGENCY LAPAROTOMY IN EASTERN UGANDA: A MIXED METHODS STUDY
REFNo: HS7329ES

To explore the factors contributing to delays in accessing definitive treatment, perioperative care practices, and outcomes of emergency laparotomy patients in Eastern Uganda.
Uganda 2026-05-20 18:25:58 2029-05-20 Medical and Health Sciences Non-Clinical Trial Degree Award
Mary Aleni
ID:
Adherence to Immediate Postnatal Care Guidelines in Arua, Uganda: Contextual Factors and Experiences of care
REFNo: HS7369ES

Overall objective: To assess adherence to IPNC guidelines and associated factors, explore contextual factors that influence its adherence and the experiences of postnatal mothers regarding IPNC in Arua, North Western Uganda. Specific objectives: 1.To determine the proportion of mother-baby pairs who receive the recommended package of IPNC in Arua, North Western Uganda. 2.To assess maternal, newborn and health facility characteristics associated with receipt of the recommended package of IPNC in Arua, North Western Uganda. 3.To explore the barriers and facilitators that influence adherence to IPNC guidelines in selected health facilities in Arua, North Western Uganda. 4.To explore the experiences of postnatal mothers regarding IPNC in Arua, North Western Uganda.
Uganda 2026-05-15 19:06:27 2029-05-15 Medical and Health Sciences Non-Clinical Trial Degree Award
Morris  Rutakingirwa Kyozo
ID: UNCST-2024-R004945
Feasibility of a Ketogenic Diet as an Adjunctive Therapy in HIV/AIDS-related Meningitis
REFNo: HS7397ES

1.Primary objectives 1.1 Observational (stage 1): To describe the dietary patterns and nutritional state of patients hospitalized for suspected meningitis during the first 2 weeks of hospitalization. 1.2 Pilot (stage 2): To assess the feasibility of implementing a ketogenic diet during in-patient hospitalization for patients with suspected meningitis during the first 2 weeks of hospitalization. Secondary objectives 1. To observe blood glucose and ketone measurements over the course of hospitalization, including how many patients are in ketosis at baseline, and the time to enter ketosis for patients on a keto diet. 2. To evaluate the safety of implementing a ketogenic diet in patients with suspected meningitis by monitoring instances of hypoglycemia. 3. To assess the adherence of patients and/or their caregivers to consistently complete food records (food log and 24-hour recall form) during hospitalization, up to 14 days. 4. To assess the acceptability of a ketogenic diet as an additional therapeutic in the context of in-patient hospitalization in Uganda. 5. To evaluate whether diet or nutritional state are correlated with the incidence or severity of meningitis symptoms or infection outcome over 18 weeks.
Uganda 2026-05-15 19:04:17 2029-05-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Emmanuel Candia
ID: UNCST-2025-R021325
Community Violence from land-related conflicts in Madi-Okollo District, Uganda: Extent, determinants, and potential countermeasures
REFNo: SS5136ES

1. To estimate the burden of land-conflict-related communal violence in Madi Okollo
District.
2. To establish the determinants of land-conflict-related communal violence in Madi Okollo District.
3. To assess the perceptions of the stakeholders regarding the causes and solutions to landconflict-related communal violence in Madi Okollo District.
4. To assess the effectiveness of the existing policy and legal framework in reducing landconflict-related communal violence in Madi Okollo District.

Uganda 2026-05-15 19:00:56 2029-05-15 Social Science and Humanities Non-Clinical Trial Degree Award
JOSELYN RWEBEMBERA
ID: UNCST-2021-R013915
Rheumatic Heart Disease: Exploring Patient-Preferred Attributes for Stigma Reduction (REPAIR)
REFNo: HS7351ES

To assess the prevalence and correlates of internalized and perceived stigma among individuals (aged ?12 years) who are relatives/caretakers of RHD patients (affiliate stigma).,To assess the prevalence and correlates of perceived and personalized stigma among individuals (aged ?12 years) living with RHD (primary stigma).,To determine the prevalence and correlates of stigmatizing attitudes and behaviours towards RHD among community members without RHD (aged ?12 years)., The overall objective of REPAIR is to systematically characterize stigma related to RHD in Uganda. ,
Uganda 2026-05-15 18:59:02 2029-05-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Elizabeth Kaudha
ID: UNCST-2025-R017151
A Phase 3b, open-label, multicenter, continued access study for participants transitioning from ViiV Healthcare-sponsored or ViiV Healthcare collaborative parent studies for HIV treatment.
REFNo: HS7588ES

The main objective of the study is to provide continued access to study interventions for participants who were enrolled and treated in ViiV Healthcare-sponsored or ViiV Healthcare-collaborative parent studies and who continue to experience clinical benefit, and to describe the continued use and safety of the study intervention. The specific objectives of this study are, Reasons for discontinuation of study intervention Incidence and outcome of serious adverse events (SAEs) Incidence and outcome of adverse events of special interest (AESIs)
Uganda 2026-05-15 18:55:49 2029-05-15 Medical and Health Sciences Clinical Trial Non-degree Award
Jensen Wainwright
ID: UNCST-2025-R018032
Stable isotope ecology of Ugandan small mammals
REFNo: NS1182ES

To measure the diets of small mammals (rodents and shrews <5kg) in Ugandan ecosystems. We aim to assess how small mammal diet changes in response to vegetation cover. This project will provide a base for measuring how small mammals respond to habitat change caused by climate change.
) To collect small mammal osteological remains from raptor pellets that accumulate below raptor roosts in two protected areas in Uganda: Kibale and Queen Elizabeth National Parks.
2) To measure the proportional abundance of grass, forbs, and woody plants surrounding each raptor roost and collect plant and soil samples.
3) To measure the isotopic composition of the small mammal teeth collected from raptor roosts.
4) To collect tooth enamel samples opportunistically from skeletons of naturally deceased large mammals (ungulates, non-human primates, carnivores) found in study areas.
USA 2026-05-15 18:51:33 2029-05-15 Natural Sciences Non-Clinical Trial Degree Award
MUSINGUZI FRED
ID: UNCST-2025-R023164
ORGANIZATIONAL PROCESS OPTIMIZATION, TECHNOLOGICAL ADOPTION AND BUSINESS PERFORMANCE OF BEVERAGE FIRMS IN UGANDA: A CASE OF WATER BOTTLING FIRMS IN UGANDA
REFNo: SS5242ES

I. To examine the effect of Process Standardization on the business performance of beverage firms in Uganda. II. To assess the impact of Process Automation on the business performance of beverage firms in Uganda. III. To evaluate the relationship between a Continuous Improvement Culture and the business performance of beverage firms in Uganda. IV. To analyze how Customer-Centric Process Design influences the business performance of beverage firms in Uganda.
Uganda 2026-05-15 17:23:03 2029-05-15 Social Science and Humanities Non-Clinical Trial Degree Award
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