Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
RITAH KICONCO
ID: UNCST-2021-R013263
MOLECULAR CHARACTERIZATION OF ANGIOTENSIN CONVERTING ENZYME GENE POLYMORPHISMS AMONG TYPE 2 DIABETES MELLITUS NEPHROPATHY IN SOUTHWESTERN UGANDA
REFNo: HS5520ES

Objectives:

Main Objective
1. To characterize angiotensin-converting enzyme gene polymorphisms and determine their relationship with the biomarkers of nephropathy and metabolic indicators as well as explore the barriers and motivators to screening for nephropathy among individuals with type 2 diabetes mellitus living in southwestern Uganda.
Specific Objectives
1. To conduct a systematic review on the ACE I/D polymorphisms and the urine albumin-to-creatinine ratio as predictive markers of nephropathy among adult type 2 diabetes mellitus patients.
2. To establish the ACE alleles and genotypes present in the genome of patients with T2D at the MRRH in SW in Uganda.
3. To determine the association between ACE gene polymorphisms and nephropathy biomarkers among T2D patients at the MRRH in SW Uganda.
4. To determine the association between ACE gene polymorphisms and metabolic indicators among T2D patients at the MRRH in SW Uganda.
5. To explore the barriers and motivators to screening for nephropathy as a health-seeking behavior among T2D patients receiving healthcare at the DM clinic in MRRH in SW Uganda.
Uganda 2025-02-20 17:50:43 2028-02-20 Medical and Health Sciences Non-Clinical Trial Degree Award
VINCENT MUBANGIZI
ID: UNCST-2024-R004232
RAMPS: REDUCING ALCOHOL PROBLEM DRINKING AND MALNUTRITION THROUGH INCOME-GENERATING PEER SUPPORT GROUPS
REFNo: HS5394ES

To document and evaluate the first peer support groups for men with alcohol problem drinking in Isingiro district
Uganda 2025-02-20 17:49:15 2028-02-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eva  Laker Odongpiny Agnes
ID: UNCST-2024-R004807
Lived Experiences of Mixed Groups of Patients on Dolutegravir after Gaining Clinically Significant Weight.
REFNo: HS5195ES

A) Primary objective (Objective 1)
To explore the lived experiences of PLWH who gained weight after starting dolutegravir and whether these experiences vary among different subgroups.
B) Secondary objective (Objective 2)
To examine the sources of information PLWH have on weight gain and how that shapes their
perceptions.
C) Secondary objective (Objective 3)
To explore how the knowledge of the health risks of excessive weight gain and the willingness of patients to take measures to lose weigh
Uganda 2025-02-20 17:47:39 2028-02-20 Medical and Health Sciences Non-Clinical Trial Degree Award
Katie Slocombe
ID: UNCST-2024-R016225
Development of cognition and communication from infancy to late childhood across different societies
REFNo: SS3663ES

The overall objective of this project is to understand the impact of the socio-cultural environment on the development of communication and social cognition and the developmental processes that lead to similarities and differences in adult human behaviour across the globe. The specific objectives are to address the three research questions below with the Ugandan sample: 1. To understand how aspects of physical, emotional and social cognition, and communication develop from infancy through childhood into adult-like forms within in a rural population of Uganda 2. To understand the socio-cultural context that the participants are developing in. 3. Does individual variation in socio-cultural environmental factors predict individual variation in performance in social cognition tasks?
UK 2025-02-20 17:46:27 2028-02-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ombeva  Malande Oliver
ID: UNCST-2024-R004335
Understanding barriers and Strengthening Services for HPV vaccination among adolescents living with HIV in Kampala Metropolitan.
REFNo: HS5254ES

4. To document lessons and experiences drawn from piloting outreach HPV vaccine services at Joint Clinical Research Centre (JCRC) and Mildmay Uganda (MUg). ,3. To pilot HPV vaccination outreach service and education for adolescents living with HIV and attending HIV care and treatment at the Joint Clinical Research Centre (JCRC) and Mildmay Uganda (MUg). ,2. To determine the knowledge, attitude and practices that influence HPV vaccine uptake among adolescents living with HIV and attending HIV care at Joint Clinical Research Centre (JCRC) and Mildmay Uganda (MUg). ,1. To estimate the HPV vaccine coverage among adolescents living with HIV attending Joint Clinical Research Centre (JCRC) and Mildmay Uganda (MUg).,
Kenya 2025-02-20 17:45:09 2028-02-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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