Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Ronald Kiguba
ID: UNCST-2019-R000844
Understanding adverse drug reactions to dolutegravir and isoniazid in people living with HIV in Uganda: incidence, risk factors, management and patient reporting
REFNo: HS3364ES

To determine the incidence, characteristics and risk factors of ADRs to DTG/ IPT in PLHIV in Uganda,To identify barriers and facilitators of using the app to report ADRs by PLHIV in Uganda,To determine the rate of ADR-reporting by PLHIV at selected ART-sites in Uganda,To implement the Med Safety app to promote ADR-reporting by PLHIV in Uganda,To identify genetic polymorphisms associated with DTG-induced weight gain and hyperglycaemia, and isoniazid-related hepatotoxicity, using the GWAS approach among PLHIV in Uganda,To investigate the prevention, monitoring, management of ADRs to DTG/ IPT in PLHIV in Uganda,
Uganda 2024-07-22 16:37:17 2027-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Elisa  Macchi
ID: UNCST-2023-R004097
Pressure to Hire, Technology Adoption, and Productivity: Experimental Evidence from Uganda
REFNo: SS2013ES

1. The project aims at contributing to several strands of the literature. First, an emerging literature
hasshown how social- and self-image concerns affect the labor market through changesin the labor
supply

2. Our evidence suggests that the reputational concerns associated to hiring and technology
adoption decisions are induced by resource-sharing practices with kin and neighbors.

3. Finally, our work links to the literature on cross-country differences in productivity. Lewis et al.
(1954) observed that developing economies have a large “traditional sector” where marginal
productivity is low and where workers may be compensated above their marginal product through
informal arrangements (see Gollin (2014) for a recent discussion). When wages do not equal
marginal product, workers may be employed in relatively less-productive tasks, resulting in
misallocations. Gollinetal
Italy 2024-07-22 16:32:03 2027-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
Patience Atuhaire
ID: UNCST-2023-R007423
TORCHES (TOXOPLASMOSIS, RUBELLA, CYTOMEGALOVIRUS, HERPES AND OTHER AGENTS LIKE SYPHILIS) and relation to Preterm Delivery and Low birth weight among pregnant women living with HIV and their babies in the IMPAACT 1077BF trial
REFNo: HS4352ES

Assess/evaluate the associations between select peripartum infections with risk of PTD and LBW, across the ART groups reported in PROMISE,assess the prevalence of select peripartum co-infections (TORCH infections) among PROMISE 1077BF women living with HIV and their HEU babies at the MU-JHU CRS in Kampala Uganda using stored plasma specimens obtained at delivery,
Uganda 2024-07-22 15:03:09 2027-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Douglas Bulafu
ID: UNCST-2021-R011774
From COVID-19 to Ebola: How did lessons on Maintaining Essential Health Services during the COVID-19 Pandemic inform the Ebola response in Uganda?
REFNo: HS4422ES

5. To compare disruption to essential health services due to COVID-19 and Ebola in Mubende and Kassanda districts of Uganda.,4. To estimate the effect (disruption) of COVID-19 and Ebola in Mubende and Kassanda districts of Uganda.,3. To explore the challenges faced during implementation of public health and social measures during the Ebola epidemic in Uganda.,2. To document how lessons from previous pandemics informed the application of public health and social measures during the Ebola epidemic in Uganda.,1. To document how lessons from previous epidemics informed the health system adaptations to ensure the continuity of essential health services during the Ebola epidemic in Uganda.,To compare disruption to essential health services during COVID-19 and the 2022 Ebola outbreak and document how lessons from the COVID-19 pandemic informed the Ebola response in Uganda to inform how to prevent and respond to future epidemics.,
Uganda 2024-07-22 15:02:01 2027-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Abbey Kato
ID:
Child art: a meaning-making mechanism for children about their gender[ed] experiences and perceptions
REFNo: SS2341ES

To interrogate children’s visual art expression as a model for gender sensitization.,To examine the gender[ed] narratives that emerge from the child art experiences and perceptions expressed in the child art.,To explore children’s experiences and perceptions of their day to day life expressed through child art.,The main objective of the study is to explore how child art can be used as a meaning-making mechanism by children to express their everyday life gender[ed] experiences and perceptions.,
Uganda 2024-07-22 14:57:37 2027-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
Daniel Mwandah Chans
ID: UNCST-2022-R008880
Antimicrobial Stewardship in Critical Care: Prevention of the Transmission of Multi-Drug Resistant Superbugs in the Intensive Care Unit of Mbarara Regional Referral Hospital (AMSICU)
REFNo: HS4682ES

6. Develop an IPC protocol for the ICU.,5. Provide training on the role of pharmacokinetics (PK) and pharmacodynamics (PD) in managing critically ill patients in order to optimize antimicrobial therapy.,4. Develop a treatment algorithm for the selection of the initial antibiotic therapy and antimicrobial therapy de-escalation in the ICU.,3. Establish the use of biomarkers for rapid identification of ICU patients with bacterial infections.,2. Document the baseline antimicrobial resistance patterns for the ICU.,1. Establish a structured antibiotic stewardship program in the ICU at MRRH involving intensivists, microbiologists, nurses, specialists, clinicians, clinical pharmacists, hospital administrators and support staff.,The overall aim of the project is to prevent transmission of multi-drug resistant (MDR) superbugs in the intensive care unit (ICU) at Mbarara Regional Referral Hospital (MRRH) through building capacity of clinicians for antimicrobial stewardship (AMS) and infection prevention and control (IPC) for improved patient outcomes,
Uganda 2024-07-22 14:52:09 2027-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
KYARIKUNDA MONICA
ID: UNCST-2023-R005922
Community Based Tourism Enterprises’ appraisal and community conservation outcomes amidst changing demographics around Bwindi Impenetrable National Park.
REFNo: SS2416ES

To determine strategic initiatives for enhancing CBTEs’ performance for better community conservation outcomes in the digital era amidst changing demographics,To explore how the changing demographics have affected the implementation and performance of CBTEs around Bwindi Impenetrable National Park,To establish the CBTEs’ performance and community attitudes’ trend towards conservation of BINP,To characterize and map the spatial and temporal distribution of community Based Tourism Enterprises around Bwindi Impenetrable National Park. ,To determine barriers and facilitators of CBTEs’ performance and resultant community conservation outcomes of Bwindi Impenetrable National Park amidst changing demographics,
Uganda 2024-07-22 14:46:50 2027-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
Patrick Kagurusi Tumusiime
ID: UNCST-2021-R012687
Baseline evaluation for Action to Scale Up Reduction of Teenage Pregnancies Among Vulnerable Girls in Eastern Uganda.
REFNo: SS2455ES

The baseline seeks to benchmark the current performance in various indicators of project in Namutumba and Bugiri districts where the project will be implemented before actual project implementation starts.
Uganda 2024-07-22 14:45:11 2027-07-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Peter Olds
ID: UNCST-2023-R006240
Burden of disease and attitudes towards cancer care among adult cancer patients in Mbarara, Uganda
REFNo: HS4303ES

Aim #1: Describing the burden of disease among patients receiving care at the adult oncology clinic at the Mbarara Regional Referral Hospital. We will conduct a retrospective chart review of all adult patients receiving care at the outpatient oncology clinic and inpatient oncology ward at the Mbarara Regional Referral Hospital between January 2019 and December 2023. We will define the burden of disease as the numbers and types of cancers of patients cared for at MRRH. We will conduct a chart review collecting data on demographics, primary diagnoses, comorbidities, treatment modalities, and outcomes. Aim #2: Qualitative understanding of patient attitudes toward cancer care, specifically in Mbarara. We will interview up to 30 patients with cancer or who have undertaken cancer care at the Mbarara Regional Referral Hospital’s Adult Cancer Clinic, and conduct semi-structured qualitative interviews with the goal being to understand their experience with cancer care in Mbarara. We will focus on understanding the role of the clinic, the physicians, and nurses in the patient’s lives and how this affects their journey through receiving cancer care.
USA 2024-07-22 14:42:30 2027-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Thereza Piloya Were
ID: UNCST-2019-R000491
Development of a Training program to improve management of Type 1 Diabetes in the school setting-The Ugandan experience
REFNo: HS4398ES

To develop a T1D training program for school staff (teachers, nurses and matrons) in Ugandan schools to support the care of children and adolescents living with T1D at school by understanding the organization of T1D care in schools and provision of knowledge to the staff.
Uganda 2024-07-22 13:21:51 2027-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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