Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Creed  Irena Frances
ID:
Assessing cyanobacteria risks in Ugandan crater lakes through historical and contemporary perspectives
REFNo: NS679ES

- To reconstruct phycological time series to establish baseline conditions in the Crater Lake district of western Uganda and determine if (and when) cyanobacteria abundance and toxin-producing potential have changed over time. (Paleolimnology)

2) To examine the historical and societal influence of local (e.g., land use) and regional (e.g., climate) stressors on regulating cyanobacteria abundance and toxin-producing potential. (Paleolimnology)

3) To characterize spatiotemporal variation in cyanobacteria risks and determine the societal influences of local (e.g., land use) and regional (e.g., climate) stressors on regulating cyanobacteria abundance and toxin-producing potential. (Field Survey)

 Canada 2023-12-21 10:18:34 2026-12-21 Natural Sciences Non-Clinical Trial Non-degree Award
Victoria Nankabirwa
ID: UNCST-2021-R011871
 Longitudinal Neurodevelopment in a Sub-Saharan Africa Cohort (LONISAC study)
REFNo: HS3405ES

1. To describe brain development (white matter volume, grey matter volume and total brain
volume) trajectories as measured by MRI among typical children from birth to 5 years of age
2. To describe patterns of motor, cognitive, language and social-emotional development among
typical children from birth to 5 years of age
3. To describe patterns of physical growth among typical children from birth to 5 years of age
4. To explore prenatal and postnatal factors associated brain and neurocognitive development
(school readiness) at 5 years of age
5. To describe the association between total white matter volume and the global scale for early
development (GSED) scores
 Uganda 2023-12-21 10:17:30 2026-12-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Edith Namakula
ID: UNCST-2022-R006923
 Burden of antibiotic use among outpatients at Mulago National Referral Hospital, Uganda.
REFNo: HS3440ES

1. To determine the prevalence of antibiotic prescription among outpatients at Mulago National Referral Hospital, Uganda.
2. To determine the appropriateness of antibiotic prescription among outpatients at Mulago National Referral Hospital, Uganda.
3. To determine the factors associated with antibiotic prescription among outpatients at Mulago National Referral Hospital, Uganda

Uganda 2023-12-21 10:16:27 2026-12-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Freddy Kitutu Eric
ID: UNCST-2020-R014751
 Realist Evaluation and Learning in a Multi-country Medical OXYgen Program (REAL-MOXY)
REFNo: HS3444ES

To understand the perspectives of a) patients/caregivers, b) healthcare workers, managers and biomedical engineers/technicians.,To examine how pulse oximetry and oxygen are used by nurses and medical officers, why, and how this impacts on patient care.,To follow patient journeys from arrival through the first 4 hours of care, to understand the sequence of care for acutely unwell children, including how pulse oximetry and oxygen are integrated with other aspects of emergency care.,To map care pathways (as they are intended) for children (<15 years) with four hypothetical clinical scenarios in each participating facility. ,To identify facilities with high and low functioning oxygen systems, based on current pulse oximetry and oxygen-related clinical practices and facility oxygen readiness.,To understand how oxygen and pulse oximetry are used (or not used) at a facility level, and to identify opportunities for strengthening oxygen systems for beneficiaries, users and managers. ,
 Uganda 2023-12-21 10:12:51 2026-12-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Gertrude Nanyonjo Gawaya
ID: UNCST-2022-R005857
 CELEBRATE: Acceptability and Feasibility of bnAbs for Infant HIV Prevention in South Africa and Uganda
REFNo: HS3466ES

1. Understand acceptability and preferences for product attributes and identify factors that influence the adoption of bnAb prevention products for post-natal prophylaxis among healthcare providers, mothers, family members, and community stakeholders.
2. Identify special considerations for administering bnAbs to infants in the post-natal period, including challenges, perceived benefits, and feasibility considerations.
3. Understand key health system and programmatic perspectives including challenges and feasibility of introducing bnAb for post-natal prophylaxis among health service providers and policy makers.

 Uganda 2023-12-19 11:29:43 2026-12-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Adrian Muwonge
ID:
Piloting a Digital One Health platform for AMR surveillance
REFNo: HS3391ES

1.Testing the utility of our mobile phone application prototype for harmonizing metadata capture 2. Piloting the use of long-read sequencing of routinely cultured pathogens (Escherichia coli and Klebsiella spp.) 3. Developing a portable and integrated data workflow to feed into our prototype data sharing and analysis web portal 4.Supporting local capacity building through training seminars on long read sequencing and data analysis. The output of this project will allow us to demonstrate and evaluate the feasibility and challenges of integrating One Health as a shared resource
 Uganda 2023-12-19 11:27:37 2026-12-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dennis Ssesanga Ernest
ID: UNCST-2023-R008022
 EFFECT OF MHEALTH COMMUNICATION ON STIGMA AND RETENTION IN CARE AMONG YOUTH LIVING WITH HIV AND LINKED TO CARE IN UGANDA.
REFNo: SS2215ES

1. To explore the effect of mhealth communication on stigma among youth living with HIV and linked to care in Uganda.
2. To systematically develop and evaluate an mHealth intervention on stigma and retention in care among youth living with HIV and linked to care in Uganda.
3. To investigate the determinants of stigma and retention in care among youth living with HIV and linked to care in Uganda.
4. To determine the effect of mhealth communication on retention in care among youth living with HIV and linked to care in Uganda.
 Uganda 2023-12-19 11:26:33 2026-12-19 Social Science and Humanities Clinical Trial Degree Award
Beatrice Francis Robinah Nassanga
ID:
Factors associated with immunogenicity of tuberculosis vaccines in Ugandan adolescents
REFNo: HS3343ES

1. To determine the impact of baseline infectious exposures and sociodemographic factors on the immunogenicity of BCG revaccination and of candidate TB vaccine “ChAdOx1-85A prime – MVA85A boost” in Ugandan adolescents 2. To characterise the baseline innate immune microenvironment and its impact on the immunogenicity of BCG revaccination and of candidate TB vaccine “ChAdOx1-85A prime – MVA85A boost” in Ugandan adolescents 3. To characterise the baseline T and B cell immune microenvironment and its impact on the immunogenicity of BCG revaccination and of candidate TB vaccine “ChAdOx1-85A prime – MVA85A boost” in Ugandan adolescents
 Uganda 2023-12-19 11:23:12 2026-12-19 Medical and Health Sciences Non-Clinical Trial Degree Award
Achilles Katamba
ID: UNCST-2019-R000540
 Attitudes and Beliefs Around Smoking Behaviors and Smoking Cessation Among People Living with HIV and Healthcare Providers in Uganda
REFNo: HS3301ES

to understand smoking behaviors and attitudes and beliefs around smoking cessation among PLWH, to mitigate risk factors for cancer in this population. We also seek to explore underlying factors, and perceived facilitators and barriers of smoking cessation among patients and healthcare providers to promote the development of effective smoking cessation interventions for PLWH.
 Uganda 2023-12-19 11:21:20 2026-12-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Wabwire  Oduke Julius
ID:
Inclusion in Universal Primary Education and Outcomes of Learning Disabilities in Wakiso District.
REFNo: SS1957ES

1) To find out the extent to which the mechanism in school climate foster inclusion in UPE and their effect on education outcomes of learning disabilities. ,The purpose of this study is to examine the inclusion mechanisms of school climate and teachers inclusive efficacy using the ecological systems model integrated with the social cognitive theory as determinants of educational outcomes for children with learning disabilities under the universal primary education system.,
 Uganda 2023-12-19 11:19:22 2026-12-19 Social Science and Humanities Non-Clinical Trial Degree Award
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