Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Grace Kebirungi
ID:
A QUALITATIVE STUDY ON THE CAUSES OF SLOW ADOPTION OF VIRTUAL REALITY IN MEDICAL EDUCATION IN KAMPALA, UGANDA
REFNo: SIR261ES

Primary objective: To assess the causes of slow adoption of VR in medical education in Kampala ,Uganda Secondary objectives: 1. To identify perceptions of medical students, interns, lecturers at Makerere School of Medicine, doctors and medical association leads in Kampala towards use of VR in medical education. 2.To assess the VR programming capacity in Kampala, Uganda 3 To identify key policy guidelines that would empower VR in Uganda.
Uganda 2024-01-11 13:14:59 2027-01-11 Engineering and Technology Non-Clinical Trial Non-degree Award
Nazarius Tumwesigye Mbona
ID: UNCST-2019-R000664
Regulating alcohol packaging and supply to protect health in Sub-Saharan Africa: evidence from policy systems in Malawi and Uganda (RAPSSA study)
REFNo: HS3130ES

General objective
1. To identify how regulatory controls on alcohol production and distribution can be improved and effectively implemented in Sub-Saharan Africa to reduce the availability of cheap, single-use products and related harms
2. To explore contextual factors important for the transferability of findings to other Sub-Saharan countries, to inform alcohol policy development and implementation across the region.


Specific objectives

1. To identify the adoption and formulation of the bans, what mechanisms for implementation were proposed and put in place, how the bans were enforced in practice, as well as stakeholder and public perceptions of, and explanations for, intended and unintended consequences of the bans.
2. To explore contextual factors important for the transferability of findings to other Sub-Saharan countries, to inform alcohol policy development and implementation across the region.

Uganda 2024-01-11 12:40:52 2027-01-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Daniel Kibuuka Musoke
ID: UNCST-2021-R011749
Evaluation of the impact of the Public Justice System strengthening program on violence against women and children in Uganda
REFNo: SS1980ES

d) To measure change in the status of empowerment and protection of women and children against sexual and intimate partner violence including establishing the prevalence of violence against women and children. ,c) To assess change in the performance of the justice system in prevention and response to violence against women and children in Uganda, with a focus on the ability of the criminal justice processes to secure justice for victims of intimate partner violence and sexual violence against children, b) To explore changes in stakeholder confidence in the criminal justice system and the reliance of victims / survivors of intimate partner violence and child sexual violence on the criminal justice system for redress. ,a) To assess the coherence and relevance of IJM’s VAWC program including profiling changes in the legal landscape, framework and processes for handling cases of violence against women and children in Uganda,The general aim of the study is to evaluate how strengthening the public justice system to enforce law (supply side) and empowerment of sexual and intimate partner violence survivors to undertake justice (demand side) contribute towards the protection of children and women from sexual and intimate partner violence. The evaluation will be guided by the Organization for Economic Co-operation and Development (OECD) Development Assistance Committee (DAC) evaluation criteria of Relevance, Coherence, Effectiveness, Efficiency, Impact, and Sustainability to measure impact,
Uganda 2024-01-11 12:39:14 2027-01-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
DENIS OKELLO
ID: UNCST-2023-R007227
Profiling Medicinal Plants and the Corresponding Community Conservation Practices within Kigezi Region
REFNo: NS667ES

Assess the community conservation strategies for priority medicinal plants in Kanungu, Kisoro and Rubanda districts.,To assess the cultural practices in Kanungu, Kisoro and Rubanda districts to ensure sustainable utilization and knowledge transfer of the medicinal values of these plants.,To assess traditional knowledge practices regarding medicinal plants used by communities in Kanungu, Kisoro and Rubanda districts.,To identify and document medicinal plants used by communities in Kanungu, Kisoro and Rubanda districts.,To profile medicinal plants in Kanungu, Kisoro and Rubanda districts in Kigezi region and assess local community conservation practices,
Uganda 2024-01-11 12:35:14 2027-01-11 Natural Sciences Non-Clinical Trial Non-degree Award
Richard Mayanja
ID: UNCST-2022-R009948
Genetic Determinants of Kidney Function in Sub-Saharan Africa
REFNo: HS3372ES

The overall aim of this project is to identify the genetic determinants of chronic kidney disease in sub-Saharan Africa
Uganda 2024-01-11 12:32:07 2027-01-11 Medical and Health Sciences Non-Clinical Trial Degree Award
John Mark Bwanika
ID:
BUILDING MACHINE LEARNING ALGORITHMS FOR PREDICTIVE MODELLING OF THE ABILITY TO PAY FOR PRE-EXPOSURE (PREP) SERVICES, A PILOT STUDY IN KAMPALA, UGANDA.
REFNo: HS3474ES

Primary objective:
To develop and deploy an artificial intelligence (AI) modelling technique for PrEP services market segmentation.
Secondary objectives:
(i) To use machine learning and artificial intelligence modelling to analyze, and profile sub-populations that are able to pay for PrEP in Kampala.
(ii) To identify the most likely favorable pricing for PrEP
(iii) To validate the variables identified as predictors for PrEP payment from dataset analyses through focus group discussions.
(iv) To test the validity and reciprocity of the developed AI model with similar datasets from other settings.

Uganda 2024-01-11 12:31:29 2027-01-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
Evaluation of Clinical Performance and Usability of the KHB HIV I/II Ab Rapid Test (Self-Test) in the hands of untrained users. "Clinical Performance Study Plan - CPSP nr. KHB-CPH 23-039"
REFNo: HS3531ES

The objective of this laymen study is to establish and to qualify the usability of the KHB HIV Self-Test for self-testing in a low and a high prevalence HIV setting in Uganda as described in TSS-1 part 3. In addition, the layperson’s interaction with the device in terms of effectiveness and efficiency, i.e. successful/unsuccessful completion and difficulty of the critical steps as per Instructions for Use will be assessed. ,
Uganda 2024-01-11 12:30:09 2027-01-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Zubair Lukyamuzi
ID: UNCST-2021-R013107
Feasibility and Acceptability of a Barbershop Based HIV Prevention Initiative Among Heterosexual Men in Kalangala Islands, Uganda: A Cluster Randomized Trial
REFNo: HS3430ES

1. To compare completion of self-initiated HIV testing between intervention and control groups
2. To evaluate the preliminary effectiveness of the intervention on change in behaviors associated with HIV acquisition
3. To compare interest in or use of HIV prevention services between intervention and control groups
4. To evaluate the preliminary effectiveness of the intervention on incident STIs
Uganda 2024-01-08 13:20:21 2027-01-08 Medical and Health Sciences Clinical Trial Non-degree Award
Tumuhimbise Jasper Mpiriirwe
ID:
HEAD TEACHERS’ LEADERSHIP PRACTICES AND FINANCIAL PERFORMANCE IN CHURCH OF UGANDA FOUNDED SECONDARY SCHOOLS IN NAMIREMBE DIOCESE
REFNo: SS2126ES

4. To explore the influence of head teachers’ stakeholder collaboration on financial performance in the Church of Uganda Founded Secondary Schools in Namirembe Diocese. ,3. To analyze the influence head teacher’s team leadership practices on financial performance in Church of Uganda Founded Secondary Schools in Namirembe Diocese in Namirembe Diocese.,2. To assess the influence of head teachers’ values on financial performance in Church of Uganda Founded Secondary Schools in Namirembe Diocese. ,1. To examine the influence of head teachers’ vision on financial performance of Church of Uganda Founded Secondary Schools in Namirembe Diocese.,The general objective of the study is to examine the influence of head teachers’ leadership practices on financial performance of Church of Uganda Founded Secondary Schools (CFSs) in Namirembe Diocese. ,
Uganda 2024-01-08 13:18:02 2027-01-08 Social Science and Humanities Non-Clinical Trial Degree Award
Joyce Kambugu Balagadde
ID: UNCST-2020-R014996
Feasibility of Nanopore Sequencing for Classification of Pediatric Malignancies in Low Resource Settings
REFNo: HS3397ES

Expand upon our adapted unbiased Nanopore sequencing classification platform while verifying the feasibility of classification of pediatric solid tumors using GEP. Hypothesis: Unbiased Nanopore sequencing can be implemented and can accurately classify pediatric cancer in low and middle income countries,Establish technical and human resources needed to carry out local, real-time sequencing on Nanopore platforms through optimizing existing supply chains in collaboration with Nanopore and establishing standardized virtual and in-person training of local research, laboratory, and information technology support.,Optimize and validate, within the context of use in low and middle income countries, the efficacy unbiased Nanopore sequencing platform for pediatric cancer classification after integrating a Cloud-based computational analysis pipeline. Hypothesis: Using a Cloud-based unbiased Nanopore sequencing approach, clinical laboratories in LMIC can perform sequencing with Cloud based analytical support, accurately classify pediatric cancer diagnosis and genomic subtypes.,To determine the feasibility of implementing and utilizing Nanopore sequencing for classification of pediatric malignancies, as determined by technical quality, data management, and classification accuracy.,
Uganda 2024-01-08 13:16:49 2027-01-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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