Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Marion de Vevey
ID:
How the presence of friends decreases fear and increases positive emotions: a comparative study between chimpanzees and humans
REFNo: SS351ES

The goal of this study is to analyse the impact of preferred social partners on emotional state in chimpanzees. We want to test whether the presence of a bond partner increases positive emotions when in a positive situation and decreases negative emotions when in negative situations in comparison to a non-bond partner presence. More specifically, fear is expected to decrease with the presence of a friend while joy is expected to increase. A comparison with humans will be done in Switzerland afterwards and therefore will stand on a swiss permit.
Switzerland 2019-10-08 2022-10-08 Social Science and Humanities Degree Award
Hodaka Kosugi
ID:
Positive deviance for dual-method promotion among women in rural Uganda
REFNo: HS439ES

The objectives of this study are to

(i) examine factors associated with condom use among married women using HECs in an HIV-prevalent setting in Uganda

(ii) identify unique behaviors that are common only among married women who practice dual-method use with their partners

(iii) evaluate an intervention for promoting dual-method use among married women using HECs.

Japan 2019-10-07 2022-10-07 Medical and Health Sciences Degree Award
Letha Victor
ID:
Trauma Pollution: an ethnographic and historical theorization
REFNo: SS316ES

The study is part of a larger ethnographic project on the phenomenon of spiritual distress in contemporary northern Uganda, for which I collected the primary data from 2013-2014 (research approved by the UNSCST). This phase of research theorizes how cultural context affects the relationship between psychic trauma (broadly conceived) and ritual pollution (haunting, unwanted spirit possession, unusual illness, misfortune, etc.). The study aims specifically to answer: How do the concepts of "trauma" (in English) and "ajwani" (in Acholi Luo; tentatively interpreted as "ritual pollution) interact discursively? How do contemporary Acholi people interpret the relationship or non-relationship between these two concepts? How have their interpretations changed or not changed since the British colonial (1900-1962) era and the era of humanitarian intervention (2005 to present)? My objective is to examine the connection between "trauma" and "ritual pollution" in 1) current cultural context, by way of observations of and interviews with the Acholi people in Uganda with whom I conducted my primary fieldwork; and 2) by historical examination of the epistemological shifts surrounding ritual pollution and psychic woundedness in Uganda, by way of archival collections on religion and medicalization.
Canada 2019-10-07 2022-10-07 Social Science and Humanities Non-degree Award
Caroline Namukwaya
ID:
A Pilot Study Exploring the Feasibility of Implementing a Child Development Counseling Program for Caregivers of Children with Sickle Cell Disease (SCD) Aged 0–3 Years in Uganda
REFNo: HS404ES

•To determine whether the Child Development Counselling program is effective in equipping caregivers of children with SCD aged 0-3 years with knowledge and skills that can be used to promote development of their children.
•To explore the experiences of healthcare providers at SCD Clinic at Mulago hospital in delivering a Child Development Counselling Program for caregivers of children with SCD aged 0-3 Years in Uganda.
•To explore the experiences of caregivers for children with SCD aged 0-3 years being part of a Child Development Counselling practiced intervention in Uganda.
•To identify the barriers and facilitators to implementing and delivering an out-patient Child Development Counselling Program for caregivers of children with SCD aged 0-3 Years in Uganda.

Uganda 2019-10-07 2022-10-07 Medical and Health Sciences Degree Award
Richard Migisha
ID:
Cardiovascular autonomic neuropathy (CAN) among type 2 diabetic patients attending MRRH, Prevalence associated factors and correlation with heart rate corrected QT (QTc) interval.
REFNo: HS413ES

To determine the prevalence of CAN among type2 diabetic patients attending MRRH, SW Uganda
2. To determine the prevalence of QTc prolongation among type 2 diabetic patients attending MRRH, SW Uganda.
3. To assess the relationship between QTc prolongation and severity of CAN in patients with type2 DM attending Mbarara Regional referral hospital, SW Uganda
4. To determine clinical and demographic factors associated with CAN among type2 diabetic patients attending Mbarara Regional referral hospital, SW Uganda

Uganda 2019-10-07 2022-10-07 Medical and Health Sciences Degree Award
Ziwena Nantongo
ID:
Population structure, genetic diversity and selection signatures in indigenous goat breeds from different agro-ecological zones of Uganda
REFNo: A50ES

1. To characterize the phenotypic diversity of indigenous goat breeds in the different agro-ecological zones of Uganda
2. To clarify the origin of indigenous goat breeds in Uganda
3. To elucidate the genetic diversity of indigenous goat breeds in the different agro-ecological zones of Uganda
4. To identify genetic markers for fecundity among indigenous goat breeds of Uganda
5. To identify selection signatures among indigenous goat breeds in various agro-ecological zones of Uganda

Uganda 2019-10-07 2022-10-07 Agricultural Sciences Degree Award
Robert Kairania
ID:
Baseline, Midterm and End of Project Evaluation Protocol for Masaka Regional mechanism
REFNo: SS334ES

The purpose of the evaluation is to collect data that will inform improvement of program implementation so that services are provided more effectively and efficiently in the region and best practices shared with other IPs in the country. The evaluation will also inform RHSP, CDC and other stakeholders about program challenges, performance gaps, progress towards achievement of set targets and program outcomes (effectiveness) in a timely manner so that implementation strategies can be maintained, scaled up or modified where necessary.
Uganda 2019-10-07 2022-10-07 Social Science and Humanities Non-degree Award
Hedmon Okella
ID:
Screening and Characterization of antimicrobial peptides from fish mucus in three major lakes of Uganda
REFNo: HS449ES

i. Determine the antimicrobial activity of skin mucus from selected fish species obtained from three major lakes of Uganda
ii. Identify the most potent antimicrobial peptides isolated from skin mucus
iii. Evaluate the toxicity of the most potent antimicrobial peptides
iv. Determine the mechanism of action of the most potent antimicrobial peptides

Uganda 2019-10-07 2022-10-07 Medical and Health Sciences Degree Award
TINO OKEDI KEVIN
ID:
OUTCOMES OF END TO END VERSUS OVERLAPPING TECHNIQUES OF REPAIR OF CHRONIC OBSTETRIC ANAL SPHINCTER INJURY, A RANDOMISED CONTROLLED TRIAL
REFNo: HS460ES

GENERAL OBJECTIVE:To compare the outcomes of end to end versus overlapping techniques of repair of chronic 3rd and 4th degree perineal tears in MNRH.
SPECIFIC OBJECTIVES:
i. To compare the proportion of patients with flatal-faecal incontinence 3 months post operatively following repair of chronic third and fourth degree perineal tears with end to end versus overlapping techniques of repair in MNRH.
ii. To compare the proportion of patients with complications; wound breakdown and perineal pain 3 months post operatively following repair of chronic third and fourth degree perineal tears with end to end or overlapping techniques of repair in MNRH.

Uganda 2019-10-07 2022-10-07 Medical and Health Sciences Degree Award
Kemirembe Goretti Maria
ID:
MICROFINANCE SERVICES AND WOMEN’S ECONOMIC EMPOWERMENT IN KYAMUHUNGA PEOPLES’ SACCO.
REFNo: SS361ES

i. To determine the effect of access to microcredit services and selected indicators of women’s economic empowerment.
ii. To determine the relationship between access to financial advisory services and indicators of women’s economic empowerment.
iii. To examine the effect of microfinance savings and selected indicators of women’s economic empowerment.

Uganda 2019-10-07 2022-10-07 Social Science and Humanities Degree Award
NIGHT MUHINDO PRIMER
ID:
cash management and financial performance of tea processing firms in Bushenyi district. a case of Igara Growers Tea factory.
REFNo: SS364ES

1.To establish the relationship between liquidity management and financial performance of igara growers tea factory
2. To examine the relationship between working capital management and financial performance of igara growers tea factory
3. To show the relationship between financial information management and financial performance of igara growers tea factory.
Uganda 2019-10-07 2022-10-07 Social Science and Humanities Degree Award
Martin Amanya
ID:
IMMUNOMODULATORY EFFECTS OF ARTAVOL®IN MALARIA PROPHYLAXIS USING A MOUSE MODEL
REFNo: HS465ES

1. To assess the cellular immune response to malaria parasites after treatment with ARTAVOL®
2. To determine the humoral immune response to malaria parasites after treatment with ARTAVOL®
3. To study the effect of crude flavonoids from ARTAVOL® on cytokine production.

Uganda 2019-10-07 2022-10-07 Medical and Health Sciences Degree Award
Lwanga  Jonathan
ID:
Prediction modelling for Infectious Diseases and Outbreak prevention
REFNo: HS473ES

To determine patterns of flow of outbreaks
Uganda 2019-09-26 2022-09-26 Medical and Health Sciences Non-degree Award
Serawit Chorito Deyno
ID:
ANTIBACTERIAL EFFECT AND SAFETY OF ESSENTIAL OIL FROM ECHINOPS KEBERICHO
REFNo: HS398ES

1.3. Objective of the study
Major objective
• To evaluate the antibacterial effect and safety of EO from E. Kebericho
Specific objectives
1. To identify and isolate main components of the EO from E. kebericho
2. To determine antibacterial activity of EO and its combined effect with existing antibiotics against S. aureus and P. aeruginosa
3. To determine antibacterial activity of main constituent of EO and its combined effect with existing antibiotics against S. aureus and P. aeruginosa
4. To examine acute and sub-acute toxicity of the EO from E. kebericho

Ethiopia 2019-09-19 2022-09-19 Medical and Health Sciences Degree Award
Heather Brown
ID:
Evaluating the Impact of a Layperson EMS System on Morbidity and Mortality of Injured Patients in Masindi, Uganda
REFNo: HS414ES

The purpose of this study is to evaluate the effectiveness of a pilot layperson EMS system for commercial boda drivers and the feasibility of using a pre-existing trauma registry to evaluate the outcomes of these patients.

Primary Objective:

Evaluate the impact of a boda driver EMS system on time to presentation for ill and injured patients.

Secondary Objectives:

1. Evaluate the purpose and rate of utilization for a lay person EMS system in Masindi, Uganda.

2. Evaluate the impact of a lay person EMS system on patient morbidity and mortality at MKMC.

USA 2019-09-19 2022-09-19 Medical and Health Sciences Non-degree Award
Sona Shah
ID:
Validation of the safety and performance of a clinical vital signs monitor on infants and neonates: A pilot study
REFNo: HS420ES

1. To assess the safety of the Neopenda wearable vital signs monitor (neoGuard) in healthy infants (aged 8 to 16 weeks) and stable neonates (aged 0-28 days)
2. To determine the performance accuracy of neoGuard device in comparison to a gold standard monitor comparable to the Edan M3A Vital Signs Monitor

USA 2019-09-19 2022-09-19 Medical and Health Sciences Non-degree Award
Mary Namubiru
ID:
Meet Your Future Job Search Effort and Aspirations of Young Jobseekers
REFNo: SS338ES

Jobseekers in developing contexts face a number of search barriers to quality employment. The most recurring ones in the literature range from liquidity constraints for travel costs (Abebe et al. 2017a) to high opportunity cost of search-time due to job availability in the informal sector (Franklin, 2017). In addition to these, young jobseekers often do not know how or where to search for jobs, might not understand their skills in relation to what employers want and are likely to have distorted expectations of wage levels and working conditions (Babcock et al. 2012). Importantly, these barriers are magnified right in the most vulnerable phase of a career: the transition into the labor market (Becker 1994, Pissarides 1994). This study seeks to investigate (i) how barriers in access to information affect search efforts, labor outcomes and aspirations of young jobseekers taking their first step in the job market, (ii) how can career-coaching and job search assistance from “the future you” help influencing their expectations and labor market trajectories and (iii) how does the trainees’ degree of identification with “the future you” affect the way in which they interpret somebody else’s experience with respect to their own future. The experimental setting is that of Vocational Training Institutes (VTIs) in Uganda and “the future you” is an alumnus of the VTI, who successfully entered the labor market after receiving the training.
Uganda 2019-09-19 2022-09-19 Social Science and Humanities Non-degree Award
Wyatt Brooks James
ID:
Community Lending and Outside Capital (CLOC)
REFNo: SS339ES

To measure the impact of community lending and outside capital on SILC members’ returns and default rate behavior, levels of liquid savings, and change in livelihood.
USA 2019-09-19 2022-09-19 Social Science and Humanities Non-degree Award
Fabien Schultz
ID: UNCST-2023-R008622
Self-medication in wild chimpanzees and mountain gorillas
REFNo: NS104ES

Observation of novel medicinal plants used for self-medication by wild chimpanzees and mountain gorillas:
The fieldwork at the field stations in Bulindi, Kibale Forest National Park, Budongo Forest Reserve, and Bwindi Impenetrable National Park will result in the documentation of potentially novel medicinal plant species used by great apes in Uganda, which will be reported in our publications.

Comparison between self-medication behavior in chimpanzees at different locations:
The study will generate a comparison between plants and self-medication techniques used by Bulindi chimpanzees (a highly disturbed habitat shared with humans) and Kibale/Budongo chimpanzees (less disturbed habitats).

Impact on modern medicine:
Through this study, we seek to integrate behavioral data with novel pharmacological screenings of plants. Without doubt, the evolution of self-medicative habits from the great apes to early hominids and modern humans has important implications for modern medicine. This project would significantly advance previous research on zoopharmacognosy (or “ape-pharmacognosy”).

Discovery of new plant and insect species and first-time pharmacological investigation of medicinal natural remedies:
I estimate that around 60% of all plant and insect species in the dense rainforests of Western Uganda and Eastern Democratic Republic of Congo remain undiscovered. As such, this project could result in the discovery of novel species, but most likely in the documentation and evaluation of novel medicinal uses in known plants. The majority of plant species used in self-medication by wild chimpanzees and mountain gorillas in the tropical rainforests of Uganda have never been screened for pharmacological activity in a lab or investigated with regard to their chemical composition.

Conservation of biodiversity:
Wild mountain gorillas are classified as Critically Endangered and chimpanzees as Endangered by the International Union for Conservation of Nature. Both great apes are highly threatened by human encroachment, forest degradation, regional political instability and disease. Through our workshop within local communities, we aim to raise awareness of the importance of protecting these creatures as well as local medicinal plants.


Germany 2019-09-19 2022-09-19 Natural Sciences Non-degree Award
Christine  Wiltshire Sekaggya
ID: UNCST-2019-R000578
The utility of urine Lipoarabinomannan as a Tuberculosis treatment monitoring tool.
REFNo: HS432ES

To describe the temporal changes of urine LAM during the first 2 months TB treatment of TB-HIV co-infected patients.
To determine the correlation between urine LAM and microbiological response measured by sputum culture among TB-HIV co-infected patients receiving anti-TB treatment.

Uganda 2019-09-10 2022-09-10 Medical and Health Sciences Non-degree Award
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