Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Robert Newton Edward
ID: UNCST-2023-R006537
Study of Genomic Integrity and Safety of Stem-Cell Gene Therapy in Cohorts in Africa.
REFNo: HS3660ES

The overall aim of this research is to establish safe and accessible gene therapies for sickle cell disease by comparing and contrasting cohorts in Africa to the data already obtained from the USA and UK thus establishing a more accurate authentic dataset. We hypothesise that patients with SCD may have elevated somatic mutation rates as compared to healthy non-SCD individuals and that the mutational processes driving the acquisition of these genetic lesions are varied from individual to individual.
UK 2024-01-24 22:45:26 2027-01-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Harriet Ajilong
ID: UNCST-2022-R005889
Assessing Vitamin D serum levels in HIV-positive adolescents 10-19 years with depression in Northern Uganda
REFNo: HS3454ES

To determine the burden of depression in HIV-positive adolescents at Gulu RRH,To assess for serum Vitamin D levels in HIV Positive adolescents 10-19 years with depressive symptoms in Gulu Regional Referral Hospital Methods,
Uganda 2024-01-24 22:30:43 2027-01-24 Medical and Health Sciences Clinical Trial Non-degree Award
Mercy Kainobwisho Kyomugasho
ID:
AN ANALYSIS OF THE BARRIERS TO PROTECTION AND COMMERCIALIZATION OF TRADEMARK ASSETS BY SMES IN THE NON-ALCOHOLIC BEVERAGE MANUFACTURING S IN UGANDA.
REFNo: SS2153ES

specific objectives of the study are to;
i. To investigate the relationship between trademark protection, licensing, valuation, collaterisation and commercialisation by SMEs in the non- alcoholic beverages in the manufacturing sector.
ii. To identify the barriers to protection, licensing, valuation and collateralisation of trademarks by SMEs in the manufacturing sector.
iii. To examine the legal and institutional framework for protecting, licensing, valuation and collateralisation of trademarks in Uganda.
iv. To propose effective ways for enhancing the protection, licensing, valuation and collateralisation of trademarks by SMEs in the manufacturing sector in Uganda

Uganda 2024-01-23 18:58:37 2027-01-23 Social Science and Humanities Non-Clinical Trial Degree Award
Joseph Rujumba Rujumba
ID: UNCST-2022-R011160
Combining monthly dihydroartemisinin-piperaquine and azithromycin for the post-discharge management of children with severe anaemia in Malawi, Kenya, and Uganda: Post-Discharge Malaria Chemoprevention -PDMC-II (acceptability and feasibility sub-study)
REFNo: HS3669ES

2)Explore perspectives of health care providers and caregivers on the feasibility of implementing PDMC with DP + AZ in children diagnosed with severe anaemia in Malawi and Uganda and generate insights for successful integration and scalability of PDMC with DP+AZ in resource-limited settings.,1)To assess health care provider and caregiver acceptability of PDMC with DP + AZ in children with severe anaemia at Malawi, Kenya, and Uganda trial sites. ,To determine the acceptability and feasibility from the health provider and patient/guardian perspective of delivering or receiving dihydroartemisinin-piperaquine (DP) and azithromycin (AZ) for the post-discharge management of children with severe anaemia in Malawi, Kenya, and Uganda.,
Uganda 2024-01-23 18:57:41 2027-01-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jane Nabwowe -
ID:
ALLELE FREQUENCY DATABASE FOR 21 SHORT TANDEM REPEATS IN THE UGANDAN POPULATION
REFNo: NS716ES

To establish the Ugandan population Y-Chromosome haplotype frequency database,To develop Ugandan population specific 21 autosomal STR markers and Y- chromosome haplotype markers allele frequency data ,To determine population genetic homogeneity among the selected tribes in Uganda ,To determine the genetic diversity of the 21 STRs in a Ugandan population by calculating the forensic and paternity efficiency parameters ,
Uganda 2024-01-23 18:56:08 2027-01-23 Natural Sciences Non-Clinical Trial Non-degree Award
MARY AJIKO MARGARET
ID:
Prevalence of Paediatric burn injuries Admitted to a hospital in Teso sub-region Eastern Uganda: lessons for prevention
REFNo: HS3484ES

The main objective of this study is to investigate the causes, characteristics, patterns, geographic determinants of paediatric burns and identifying the barriers and enablers to their prevention in a home. Specific Objective of the Study 1. To examine the typical patterns and causes of paediatric burn injuries leading to hospitalization. 2. To establish care givers’ understandings of the injury to their children, considering both injury determinants and preventive means. 3. To assess the effects of various characteristics of the living area on paediatric burn injuries. 4. To determine the enablers and barriers to the creation of safe environment, the implementation of safe practices and the use of products that control or prevent childhood burn injuries in the home.
Uganda 2024-01-23 16:58:07 2027-01-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Margaret Mangheni Najjingo
ID:
Women empowerment, normative influence and project outcomes in Central Uganda
REFNo: SS1942ES

To identify factors that influence women’s economic empowerment within farming communities.

To explore the community construction of femininities and how it influences women’s economic empowerment within agricultural project intervention areas.

To explore the community construction of masculinities and how it influence women’s economic empowerment within agricultural project intervention areas

To find out the factors that influence women’s economic empowerment and household food security within agricultural project intervention areas

Uganda 2024-01-22 11:38:01 2027-01-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Waiswa Peter
ID: UNCST-2020-R014921
EFFECTIVENESS OF THE PARTNER-LED IMPLEMENTATION IN IMPROVING DIGITAL PAYMENT AND CAMPAIGN QUALITY DURING THE YELLOW FEVER CAMPAIGN IN UGANDA: AN EXPLORATORY STUDY
REFNo: SS2221ES

To determine gender norms and relations and their influence on health workers’ response to payment systems (cash vs mobile money) and how these affect the health workers’ performance and motivation in yellow fever vaccination campaigns,To explore the effect of implementing a partner-led digital payment system on the Motivation, Satisfaction, and performance of vaccination campaign health workers,To establish the vaccination coverage of yellow fever in different geographies (equity),To document partner-led implementation process of the Yellow Fever Mass Vaccination campaign,To assess the effectiveness of partner-led Yellow Fever campaign and its effect on digital health worker payments and campaign coverage in Uganda.,
Uganda 2024-01-22 11:26:43 2027-01-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Susan  Nabadda Ndidde
ID: UNCST-2020-R014331
OUTCOMES OF PEDIATRIC PATIENTS DIAGNOSED BY MORPHOLOGY ALONE VERSUS FLOW CYTOMETRY PLUS MORPHOLOGY: A RETROSPECTIVE STUDY
REFNo: HS3352ES

To compare the treatment outcomes between patients diagnosed with the help of flow cytometry with those diagnosed without the help of flow cytometry.,To determine the accuracy of diagnosis of acute leukemia between patients diagnosed with the help of flow cytometry with those diagnosed without the help of flow cytometry.,To assess the time to treatment initiation among patients diagnosed with the help of flow cytometry and those diagnosed without the help of flow cytometry,
Uganda 2024-01-22 11:25:41 2027-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
Using Video-Enhanced Teaching to Increase Maternal Participation in Neonatal Hospital Care
REFNo: SS2030ES

3. To evaluate by survey the perspectives of healthcare workers on their availability to devote to video-assisted maternal education in a neonatal hospital unit in Uganda.,2. To identify maternal and/or neonatal factors that impact the amount of time needed to train mothers to weigh their baby, assess for danger signs, and track feeds using video-assisted teaching.,1. To determine the mean nursing time required to train mothers to perform three specific tasks: (1) weigh their baby, (2) assess for danger signs, and (3) track feeds when facilitated by video-assisted teaching.,The purpose of this study is to evaluate a video that teaches mothers how to monitor their baby in a neonatal hospital unit in Uganda. This is with the goal of reducing the amount of time healthcare workers need to spend teaching mothers and ultimately improving the quality of care that sick and small newborns receive in the hospital. ,
Uganda 2024-01-22 10:45:51 2027-01-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
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