Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Carolyne Onyango
ID:
Re-Calibration of Quantitative and Contextual Factors to Predict Child Cognitive Deficits in HIV-Exposed Children in the PROMISE/PROMOTE Study Cohorts (CD PROMOTE Study) Version 2.0, dated 08 March 2020
REFNo: HS795ES

1. To identify clinical, maternal, home-environment factors that are associated with the risk of CD among HIV exposed but uninfected children.
2. To develop a CD risk prediction tool for HIV exposed uninfected children informed by identified risk factors observed in Aim 1 and existing literature

 Uganda 2020-12-18 2023-12-18 Medical and Health Sciences Non-degree Award
Bruce Twinamasiko
ID:
FEASIBILITY OF A COMMUNITY HEALTH WORKER-LED INTERVENTION TO CONTROL HIGH BLOOD PRESSURE IN SOUTHWESTERN UGANDA: A PILOT PRAGMATIC CLUSTER RANDOMIZED TRIAL (CHIP TRIAL)
REFNo: HS881ES

1.To test whether a multifaceted intervention program will lead to blood pressure control among patients with uncontrolled blood pressure over a 12-month period compared to usual care.
2.To evaluate whether a multifaceted intervention program will improve hypertension control among hypertensive patients over a 12-month period, compared to usual care.

 Uganda 2020-12-18 2023-12-18 Medical and Health Sciences Non-degree Award
Grace Ndeezi
ID: UNCST-2019-R001802
 Effect of Vitamin D supplementation on Sickle cell disease hospitalisation and related complications among Children in Mulago Hospital: A randomised clinical trial
REFNo: HS985ES

Objectives
The overarching goal for this study is to evaluate whether vitamin D supplementation can decrease the need for hospitalisations in Ugandan children with SCD
Primary objectives:
1. To determine the frequency of hospitalisation among children with SCD supplemented with vitamin D versus placebo.
2. To determine the effect of vitamin supplementation on serum levels of 25 Hydroxyvitamin D levels in children with SCD

Secondary objectives:
To determine the:
1. Incidence of vaso-occlusive crises (VOC)
2. Incidence of acute severe respiratory illnesses
3. Severe adverse events
4. Requirements for blood transfusion among children supplemented with vitamin D versus Placebo in children with sickle cell anaemia

 Uganda 2020-12-18 2023-12-18 Medical and Health Sciences Non-degree Award
Tumuhairwe Juliet
ID:
The Challenge Initiatives Approach to City engagement – Coaching case study
REFNo: SS645ES

This study is meant to explore the successes, challenges and innovations of The Challenge Initiative’s (TCI) coaching model


Specific objectives
1. Document the intensity and focus of TCI coaching to-date, including which high-impact approaches governments most commonly request coaching for, how often, and what their impact has been.
2. Explore how local governments and service providers perceive the TCI coaching model, including, whether they believe it has been beneficial, and if so, how.
3. Understand if TCI’s coaching has led to system strengthening and improvements in the healthcare system both related to family planning and AYSRH service delivery, but also beyond. Additionally, document which system strengthening elements of coaching are most notable to TCI beneficiaries.
4. Document the ways in which TCI’s coaching has worked well and, perhaps, not worked as planned. Use this information to develop recommendations for how TCI can strengthen its coaching model.
5. Understand how the TCI coaching model can be sustained by TCI supported geographies even after a city ‘graduates’ from TCI (i.e., achieves program success and certain milestones, indicating the city no longer needs TCI’s support)

 Uganda 2020-12-18 2023-12-18 Social Science and Humanities Non-degree Award
Diana  Ntamu Nandagire
ID:
Small and Growing Businesses: A Segmentation Study in Uganda and Nigeria
REFNo: SS647ES

The purpose of the study is to test Dalberg’s segmentation framework of small and growing businesses (SGBs) by determining the effectiveness of that framework. By testing the framework, “maps” shall be created, funding gaps shall be established and recommendations made for the two African countries (Uganda and Nigeria).
The study will be guided by the following objectives;
a) To determine the extent to which the Dalberg framework defines SGBs in Uganda and Nigeria.
b) To establish the reasons why SGBs seek financing in their operations and the challenges in accessing funding.
c) To identify organisations that invest in SGBs and establish the proportion of their portfolio dedicated to SGBs.
d) To establish the total capital available in funding organisations to SGBs.
e) To establish the challenges of investing in SGBs.


 Uganda 2020-12-18 2023-12-18 Social Science and Humanities Non-degree Award
Florence Nassiwa
ID:
Effect of climate variability adaptation strategies on livelihood of smallholder vegetable farmers in Kampala District Uganda
REFNo: SS649ES

i. To establish the effect of technological development adaptation strategies on livelihood of smallholder vegetable farmers.
ii. To determine the effect of government programs and insurance adaptation strategies on livelihood of smallholder vegetable farmers.
iii. To assess the effect of farm production adaptation strategies on livelihood of smallholder vegetable farmers
iv. To establish the effect of farm financial management adaptation strategies on livelihood of smallholder vegetable farmers.
v. To evaluate constraints smallholder vegetable farmers encounter in adapting to climate variability.

 Uganda 2020-12-18 2023-12-18 Social Science and Humanities Degree Award
Kamya Moses
ID: UNCST-2020-R014203
 Impact of housing modifications combined with piperonyl butoxide (PBO) long-lasting insecticidal nets (LLINs) on the malaria burden in Uganda: a cluster-randomised trial
REFNo: HS1072ES

Primary Objective;
To evaluate the effect of housing modifications plus PBO LLINs, compared to PBO LLINs alone, on the incidence of clinical malaria in Ugandan children aged < 60 months

Secondary Objectives;
1) Epidemiology: To assess the impact of housing modifications + PBO LLINs, compared to PBO LLINs alone, on (1) parasite prevalence, and (2) prevalence of anaemia in children 6m-14y
2) Entomology: To assess the impact of housing modifications + PBO LLINs, compared to PBO LLINs alone, on (1) indoor and outdoor densities of malaria vectors; (2) entomological inoculation rate (EIR); (3) human biting rates (indoor and outdoor); and (4) To evaluate the patterns of insecticide resistance through the phenotypic and molecular detection methods, in mosquito vectors from clusters with housing modification + PBO LLINs, compared to PBO LLINs alone
3) Housing modifications: (1) To understand the local context regarding housing; (2) To assess acceptability of the housing modification interventions quantitatively, among the cohort members and the community, over time; (3) To assess acceptability of the housing modification interventions through qualitative research among the community opinion leaders and members, in both intervention and control clusters, over time; (4) To assess durability of housing modification interventions; (5) To assess environmental measures in houses with modifications + PBO LLINs; (6) To assess feasibility of housing modification including labour and materials, maintenance requirements, time required; (7) To conduct a process evaluation of the interventions, by developing a logic model, assessing the implementation of the housing modifications, and examining the mechanisms of effect
4) Economics: (1) To measure cost-effectiveness of housing modifications + PBO LLINs, compared to PBO LLINs alone, under research conditions; (2) To cost the different components of the interventions and identify factors contributing to major costs; (3) To estimate potential cost of providing housing interventions at scale over longer periods of time.

 Uganda 2020-12-18 2023-12-18 Medical and Health Sciences Non-degree Award
Elly Katabira
ID:
REDUCING STROKE BURDEN IN UGANDA USING TARGETED MANAGEMENT INTERVENTION (TEAM). A RANDOMISED, PROSPECTIVE 6 – MONTH CONTROLLED TRIAL.
REFNo: HS1094ES

Objective 1: To refine the TEAM curriculum for optimal acceptability and integration in the Ugandan setting guided by input from stakeholders (patients/family, clinicians, administrators).
Objective 2: To conduct an RCT comparing efficacy of TEAM vs. enhanced treatment as usual (ETAU) in 246 Ugandans (TEAM, N= 123; ETAU, N= 123) at high risk for stroke.
Objective 3: Identify barriers and facilitators to TEAM implementation.

Uganda 2020-12-18 2023-12-18 Medical and Health Sciences Non-degree Award
Joseph Lutaakome
ID: UNCST-2020-R008323
 A Multicenter, Adaptive, Randomized, Blinded Controlled Trial of the Safety and Efficacy of Investigational Therapeutics for Hospitalized Patients with COVID-19
REFNo: HS1099ES

SARS-CoV-2 is a novel coronavirus causing COVID-19 and has spread very rapidly. Safe and effective treatments are urgently needed. One antiviral treatment, remdesivir, and an anti-inflammatory drug, dexamethasone, have shown benefit; these are now the COVID-19 standard-of-care treatment for in patients in many parts of the world. The structure of the natural antibodies that hasten recovery from COVID-19 are now known; this means synthetic forms have been manufactured. These synthetic neutralising monoclonal antibodies (nMAb) ‘neutralise’ the virus by binding to it and prevent it from entering cells in the body, including the lungs. By giving an infusion of these nMAb(s) in addition to COVID-19 standard-of-care treatment, we hope hospitalised patients will recover more quickly.

The primary endpoint of TICO is to test whether in hospitalized adults with confirmed COVID-19 infection, the nMAb(s) result in more people with ‘sustained’ recovery i.e. discharged from hospital, alive, and home for 14 consecutive days by Day 90.

1) For everyone enrolled during stage 1 and 2 of the trial the secondary research questions are to define, the numbers of deaths through 90 days of follow-up; the number of people who experience sustained recovery over 90 days, the time to discharge from the initial hospital, and the number of days alive up to day 90.
2) Changes in the scores to assess people’s lung and respiratory function on Days 1-7, and Days 14 and 28.
3) Changes between Day 0 and Day 5 in the National Early Warning (NEW) score, this is a scoring system validated in the UK, which is able to score how sick people are, and their risk of dying, based on things like their blood pressure, pulse rate and body temperature.
4) Clinical organ failure defined by development of any one or more of the following through Day 28
a. Respiratory system dysfunction including the need for oxygen therapy or ventilation
b. Cardiac problems include heart attacks and heart failure
c. Low blood pressure requiring drug support to maintain it
d. kidney dysfunction including needing dialysis
e. liver dysfunction including liver failure and abnormal liver tests
f. Brain and nerve problems including acute confusion, strokes, brain swelling, meningitis, and weakness of the legs
g. Blood problems including major bleeding
h. thrombotic events in the veins or arteries
i. Serious infections including sepsis.
5) Safety and tolerability as measured by: grade 3 and 4 clinical adverse events, serious adverse events, or death through Day 5 and through Day 28; Infusion-related reactions of any severity and the percentage of participants for whom the infusion was interrupted or stopped prior to completion.
6) Change in the levels and types of antibodies against COVID-19, from baseline to Days 1, 3, 5 and 28 and 90.

 Uganda 2020-12-18 2023-12-18 Medical and Health Sciences Non-degree Award
Patrick  Wakida
ID:
MARKET RESEARCH STUDY TO UNDERSTAND THE MARKET POTENTIAL FOR CANCER TESTING EQUIPMENT IN UGANDA
REFNo: SS679ES

i. To understand current diagnostic and treatment pathways in breast cancer.
ii. To gain an understanding of breast cancer management including mapping diagnostic and treatment pathways
iii. To understand the processes and challenges of penetrating the invitro diagnostics products market the Uganda.
iv. To determine the need for molecular invitro diagnostics product In Uganda

 Uganda 2020-12-18 2023-12-18 Social Science and Humanities Non-degree Award
Nelson Sewankambo K
ID: UNCST-2020-R014578
 Feasibility and acceptability of Dialog+ in Primary care-Uganda
REFNo: HS1116ES

i. test the feasibility and acceptability of DIALOG+ for patients with non-communicable physical health conditions in primary care
ii. explore the adaption of Dialog+ intervention through a process of stakeholder consultation and refine the training materials to promote wider implementation and upscale
iii. explore the effect of using the adapted Dialog+ intervention on patient outcomes

Uganda 2020-12-18 2023-12-18 Medical and Health Sciences Non-degree Award
Catherine Mwesigwa
ID: UNCST-2019-R000988
 FEASIBILITY OF INTEGRATING ORAL HEALTH IN THE PRIMARY CARE OF HIV PEDIATRIC PATIENTS IN KAMPALA, UGANDA
REFNo: HS1055ES

1. To determine the factors that influence integrating oral health at pediatric HIV care facilities.
2. To assess the effectiveness of an oral health education intervention in pediatric HIV care.
3. To explore the feasibility of integrating oral health within primary HIV-care in a low-resource setting
 Uganda 2020-12-17 2023-12-17 Medical and Health Sciences Non-degree Award
Nazarius Tumwesigye Mbona
ID: UNCST-2019-R000664
 Research Protocol for the Impact and Economic Evaluation of Health Systems Strengthening Interventions in the West Nile region of Uganda
REFNo: HS1110ES

To determine the status and associated factors (i. DHSS intervention, ii. Quality of Care, iii. SBCC) of coverage of maternal and child health and nutrition services in intervention and counterfactual districts during 2019
2: To determine the status and associated factors (i. DHSS intervention, ii. Quality of Care, iii. SBCC) of use of maternal and child health and nutrition services in intervention and counterfactual districts during 2019
3: To determine the differences and the associated factors (i. DHSS intervention, ii. Quality of Care, iii. SBCC) of the change in coverage of maternal and child health and nutrition services from 2019 to 2024 between intervention and counterfactual districts
4: To determine the differences and the associated factors (i. DHSS intervention, ii. Quality of Care, iii. SBCC) of the change in use of maternal and child health and nutrition services from 2019 to 2024 between intervention and counterfactual districts
5: To establish the cost and effectiveness of DHSS, quality improvement and SBCC in the use and coverage of maternal and child health and nutrition services from 2019-2024

 Uganda 2020-12-17 2023-12-17 Medical and Health Sciences Non-degree Award
Grace Kaisa Tibagwa
ID:
Analysing routine patient data collected through the LifeHealth Network for trends of clinical and public health importance
REFNo: HS1007ES

To analyse data of patients with infectious diseases (such as malaria, HIV, TB), non-communicable diseases (such as cancer, diabetes) and serious health conditions (such as sickle cell anaemia) subscribing to the LifeHealth model for any trends of clinical and public health importance.


 Uganda 2020-12-16 2023-12-16 Medical and Health Sciences Non-degree Award
Viola  Nyakato Nilah
ID: UNCST-2021-R013698
 Sexual and reproductive health and wellbeing during COVID-19: A study protocol for online national surveys and global comparative analyses
REFNo: SS560ES

The overall goal of this global study is to better understand sexual and reproductive health among adults during COVID-19 using an online convenience sample from 23 countries. The primary study aims are listed below:
1) To determine the impact of COVID-19 social restriction measures on sexual health, with a focus on safe sex practices
2) To determine the impact of COVID-19 social restriction measures on domestic violence, with a focus on gender-based violence
3) To determine the impact of COVID-19 social restriction measures on access to essential reproductive health commodities and services, including contraceptives, abortion, maternal health services

Secondary study aims including the following:
1) To determine the impact of COVID-19 social restriction measures on mental health
2) To determine the impact of COVID-19 social restriction measures on harmful cultural practices

3) To determine the impact of COVID-19 social restriction measures on STI and HIV/AIDS testing and treatment

4) To determine the impact of COVID-19 social restriction measures on nutrition


Uganda 2020-12-16 2023-12-16 Social Science and Humanities Non-degree Award
Musa Sekikubo
ID: UNCST-2020-R014404
 Understanding COVID-19 in pregnant women and their babies in Uganda
REFNo: HS913ES

Primary objectives
• To describe the seroepidemiology of COVID-19 among pregnant women in Uganda
• To assess the risk of COVID-19 in newborn infants born to pregnant women with confirmed or probable COVID-19 and determine possible routes of mother-to-child transmission
• Secondary objectives
• To determine the clinical course and pregnancy outcomes in women infected with SARS-CoV-2 during pregnancy
• To determine the presence of SARS-CoV-2 in various mother and baby samples (serum, throat and nasal swabs, vaginal swab, placenta swabs and biopsies, and breast milk) and estimate the duration of viral excretion
• To assess the immune responses to SARS-CoV-2 in pregnant women and their babies
• To work with communities to understand perceptions surrounding infection prevention and control techniques to reduce the spread of COVID-19 amongst the pregnant population

 Uganda 2020-12-16 2023-12-16 Medical and Health Sciences Non-degree Award
Mark Jordans
ID: UNCST-2020-R014861
 Quasi-experimental study of a group-based psychosocial support intervention (movement-based activities “TeamUp”) for children affected by conflict and adversity in Uganda
REFNo: HS941ES

The aim of this quasi-experimental study is to evaluate the outcomes of the TeamUp intervention for children aged 10-14 years attending community primary schools, compared to a standard of care.
 Netherlands 2020-12-16 2023-12-16 Medical and Health Sciences Degree Award
Jolly Beyeza-Kashesya
ID:
mHealth for Improvement of Access to Maternal Health Services in the Era of Covid-19 Pandemic (SMS Maama Project)
REFNo: HS1076ES

Primary objective:
Assess whether a mHealth platform increases maternal health knowledge in the areas of birth preparedness, pregnancy and birth complications as measured by the pre- and post- survey.

Secondary objectives:
1. To provide knowledge of COVID-19 symptoms, transmission, diagnosis, and treatment, in a time of social distancing and learn

2. To improve access and linkages to maternal health services and information as well as provide appropriate referrals for pregnant women.

3. To inform the adoption of mHealth into future health delivery plans.
Uganda 2020-12-16 2023-12-16 Medical and Health Sciences Non-degree Award
Rawlance  Ndejjo
ID: UNCST-2022-R010993
 Sustainable health and multisectoral collaborations in Uganda in the COVID-19 response and post-recovery period
REFNo: HS1107ES

• To explore perspectives of key stakeholders around sustainable health and multisectoral collaborations in Uganda in the context of COVID-19 and post-COVID-19 recovery period.
• To establish the gaps around sustainable health and multisectoral collaborations in Uganda in the context of COVID-19 and post-COVID-19 recovery period.
• To explore the opportunities around sustainable health and multisectoral collaborations in Uganda in the context of COVID-19 and post-COVID-19 recovery period.
• To identify the needs around sustainable health and multisectoral collaborations in Uganda in the context of COVID-19 and post-COVID-19 recovery period.

 Uganda 2020-12-16 2023-12-16 Medical and Health Sciences Non-degree Award
Fred Kyeyune
ID:
Development of Assays for Mass screening of Sars Cov-2 infections in communities
REFNo: HS1114ES

1:To develop and optimize highly sensitive assays (index assays) for mass screening of Sars Cov-2: two types of assays will be developed: 1) assays that improve the limit of detection (LOD) of Sars Cov-2 by LAMP, q PCR and Next Generation sequencing assays 2) Low cost sequence specific assay for testing of Sars Cov-2 vrius
2: To perform a comparative analysis of the above assays to the Gold standard
assay for detection of Sars Cov-2.
Aim 3: To assess the index assays and gold standard assays for mass screening of Sars Cov-2 infections.
Uganda 2020-12-16 2023-12-16 Medical and Health Sciences Non-degree Award
Mary Grace  Nakate Nakate
ID:
Experience of Social Isolation and social distancing for Women and significant others in the Family on Continuity of Care in the First 1000 days of life During the COVID 19 Pandemic in Mbale Uganda. Version:
REFNo: HS675ES

To explore the experiences of social isolation and distancing for women on continuity of care in the first 1000 days of life during the COVID 19 pandemic at Bunghokho-Mutoto Sub-county. Mbale, District. To describe the experiences of social isolation and distancing for women’s significant others in the family on continuity of care in the first 1000 days of life during the COVID 19 pandemic at Bunghokho-Motto, Mbale District.
Uganda 2020-12-15 2023-12-15 Medical and Health Sciences Non-degree Award
Adeline Boatin
ID: UNCST-2019-R001255
 Caesarean delivery in Uganda: a mixed methods study
REFNo: HS758ES

1. To use survey methods to explore practice patterns of clinicians around caesarean usage in Uganda.

2. To use qualitative methods to explore practice patterns of clinicians and clinical policy makers around caesarean usage in Uganda

3. To describe CS rates, factors associated with CS and maternal and neonatal outcomes according to Robson group classification at Regional Referral Hospitals and large private non-profit hospitals in Uganda

Ghana 2020-12-15 2023-12-15 Medical and Health Sciences Non-degree Award
Dickens Akena Howard
ID: UNCST-2019-R000179
 Integration of mental health care in communities affected by the COVID-19 pandemic - A cluster randomized trial of 24 villages in central Uganda
REFNo: HS1009ES

Our objectives will include: (a) Documenting MHL, PD, MDD, GAD, PTSD and SUD levels in the study population, (b) Determining the effectiveness of a psycho-education intervention delivered by village health team (VHT) members on study outcomes, (c) Determining the cost and cost effectiveness of delivering a psycho-education intervention, and (d) linking individuals in need of mental health care with the MOH psychosocial teams.
Uganda 2020-12-15 2023-12-15 Medical and Health Sciences Non-degree Award
Annet Namugaya Waibi
ID:
Pedagogical approaches of English Language curriculum on learners outcome in public secondary schools in Iganga District.
REFNo: SS578ES

1. To establish ways in which the content expertise for English Language teachers defines student learning outcomes in public secondary schools in Iganga District.
2. To map out the significance of instructional design skills by English language teachers on students learning outcomes in public secondary schools in Iganga District.
3. To determine the implications of English language teachers assessment techniques on student's learning outcome in public secondary schools in Iganga District.
4. To ascertain the contributions of classroom management by English language teachers on students learning outcomes in public secondary schools in Iganga District.

Uganda 2020-12-11 2023-12-11 Social Science and Humanities Degree Award
Conrad Muzoora Kihembe
ID: UNCST-2019-R001432
 Intensified tuberculosis treatment to reduce the mortality of HIV-infected and uninfected patients with tuberculosis meningitis: a Phase III Randomized Controlled Trial. ANRS 12398 INTENSE-TBM
REFNo: HS804ES

The Primary objective is to assess the efficacy of two interventions to reduce mortality from TBM in adolescent and adults with or without HIV co-infection in sub-Saharan Africa:
• Intensified TBM treatment, compared to WHO standard TBM treatment
• Aspirin compared to not receiving Aspirin (placebo).

 Uganda 2020-12-10 2023-12-10 Medical and Health Sciences Non-degree Award
Irene Among Among
ID:
A Gender, youth and social inclusion analysis of Pathfinder’s family planning program in Kyegegwa, Kyenjojo, Kibaale, Kyankwanzi, Buliisa, Ntoroko, Bundibugyo, Kiryandongo, Gomba, Rakai and Butambala districts
REFNo: SS646ES

1. To identify the vulnerable/marginalized/underserved and hard-to-reach population segments in the FPA catchment districts.
2. To define the systemic barriers faced by such population segments in accessing SRH/FP information and services, structured around the six domains of USAID’s gender analysis framework - access, beliefs, practices, time/space, rights, and power.
3. To make recommendations on innovative approaches that the FPA could take to address barriers and improve access to quality reproductive health services and adoption of positive reproductive health behaviors.
4. With precision to gender and youth, to provide further recommendations as appropriate, on innovative strategies based on local needs, to mainstream gender and youth programming into national/district health planning by detailing specific gender-focused and youth-focused activities for each result area of the project.

 Uganda 2020-12-10 2023-12-10 Social Science and Humanities Non-degree Award
Lawrence Mugisha
ID:
MONITORING OF DISEASES AND ANTIMICROBIAL USE IN POULTRY FARMING BY USE OF INFORMATION AND COMMUNICATION TECHNOLOGY TO CONTROL ANTIMICROBIAL RESISTANCE (AMR) IN WAKISO DISTRICT; UGANDA
REFNo: A100ES

The overall objective of the project is to provide an ICT framework for improved monitoring and control of AMU and AMR in poultry farmers in Wakiso District, Uganda.

Specific objectives

• To perform a stakeholder analysis in order to establish all players in poultry farming systems in Wakiso District
• To examine practices, attitudes, knowledge and behavior of poultry farmers in Wakiso District
• To collect data on poultry diseases, access and use of antibiotics in Wakiso district
• To develop and deploy an ICT platform to monitor AMU, AMR and disease prevalence’s in poultry in Wakiso District
• To examine the role of ICT in the implementation and management of Poultry projects in Wakiso District

Uganda 2020-12-09 2023-12-09 Agricultural Sciences Non-degree Award
Haruna Muwonge
ID: UNCST-2019-R000128
 SUPPLEMENTS, HERBS AND DOPING PRODUCTS USAGE AMONG UGANDAN ATHLETES AND COACHES
REFNo: SS507ES

1. To evaluate supplement and herbal product usage amongst athletes from all major sporting codes in Uganda
2. To evaluate the usage of doping substances or methods amongst Ugandan athletes from all major sporting codes.
3. To determine the existing framework for intervening in herbal products usage among athletes and support personnel in Uganda
4. To examine the existence of anti-drug abuse interventions targeting the misuse of herbal products among Ugandan athletes and support personnel.
5. To determine the level of susceptibility to doping agent usage among Ugandan athletes and suggest recommendations for an intervention.

 Uganda 2020-12-08 2023-12-08 Social Science and Humanities Non-degree Award
Dominic Kathiya Lokeris
ID:
Characterization of Cross Border Livestock Mobility and Utilization of Rangeland Resources: A Case Study of Karamoja Cluster
REFNo: A91ES

Broad Objective:
To characterize cross-border livestock mobility and assess the utilization of rangeland pastures and water in the Karamoja cluster.

Specific objectives:
1.To describe cross-border livestock mobility in Karamoja cluster.
2.To assess the knowledge, practices and perceptions of pastoral communities on utilization of rangeland pastures and water in Karamoja Cluster.
3.To establish the decision makers of livestock mobility and utilization of the rangeland pastures and water in Karamoja Cluster.

 Uganda 2020-12-08 2023-12-08 Agricultural Sciences Degree Award
Wilfred Eneku
ID:
Molecular and Sero-epidemiology of zoonotic rickettsia in five districts of Uganda
REFNo: HS897ES

1. To determine seroprevalence and risk factors to rickettsioses in the five districts from archived serum samples and the accompanying secondary data
2. To characterize rickettsia in Vectors in five districts of Uganda
3. To assess the relative densities of ticks and fleas on animals and environment in the five districts of Uganda

 Uganda 2020-12-08 2023-12-08 Medical and Health Sciences Degree Award
Kristie McComb
ID:
Evaluation of the Patient Navigation Program at Uganda Cancer Institute
REFNo: HS1014ES

The goal of this study is to document the experiences and lessons learned (through a baseline and endline process evaluation), and the ways in which this program improved outcomes for cancer patients (through an outcome evaluation). These evaluations will document best practices for other countries considering similar projects, provide programmatic evidence on the usability and effectiveness of the program development methodology, and guide development of a resource toolkit for other health institutions like UCI seeking to start a patient navigation program.

The evaluation questions are:

Process Evaluation (2020 and 2021)
1. Coordination and Referral: Has the patient navigation program increased coordination/ referral of patients within Uganda Cancer Institute (UCI) and with other support services (e.g. Civil Society Organizations (CSO), psychosocial services and other necessary services)?
2. Fidelity and Adaptation: To what extent is the patient navigation program implemented as intended and what changes to the program have been made over time?
3. Improving Understanding of Care: To what extent does the patient navigation program reduce barriers to understanding cancer diagnosis and accessing treatment services and how does patient navigation increase adherence to patient treatment plans?
4. Training and Technical Assistance: How effective is the training and technical assistance provided by American Cancer Society (ACS) in supporting new patient navigation program design, preparation and implementation?
5. Sustainability: How prepared is the program to transition to UCI ownership?

Outcome Evaluation (2023)
1. To what extent, if at all, are the program activities focused on addressing the needs of the target population?
2. To what extent do decision makers and other stakeholders view patient navigation as the right intervention to address challenges to patient access to cancer treatment?
3. How effective is the patient navigation program at improving hospital processes and service delivery?
4. How effective is the patient navigation program at improving desired outcomes at the individual patient and caregiver level?
5. How effective is the training and technical assistance provided by ACS in supporting new patient navigation program design, preparation and implementation?
6. To what extent is the patient navigator program likely to continue after ACS support ends?

 USA 2020-12-08 2023-12-08 Medical and Health Sciences Non-degree Award
Pontiano  Kaleebu
ID: UNCST-2020-R019901
 Clinical characterization and preparedness for COVID-19 disease (CCP)
REFNo: HS1041ES

• Describe the clinical features of COVID-19 and monitor the progress of all hospitalized patients including what is working and what is not.
• Describe, where appropriate, the response to treatment, including supportive care and novel therapeutics.
• Observe, where appropriate and feasible, pathogen replication, excretion and evolution, within the host, and identify determinants of severity and transmission using high throughput sequencing of pathogen genomes obtained from respiratory tract, blood, urine, stool and other samples.
• Characterise, where appropriate and feasible, the host responses to infection and therapy over time, including innate and acquired immune responses, levels of immune signaling molecules in relevant body compartments and gene expression profiles in peripheral blood.
• Understand transmissibility and the probabilities of different clinical outcomes following exposure and infection.
• To describe COVID 19 related haematological and biochemical changes

 Uganda 2020-12-08 2023-12-08 Medical and Health Sciences Non-degree Award
Charity Okaba
ID:
Understanding Community-oriented Prosocial Behaviors in Uganda
REFNo: SS641ES

The proposed study aims to investigate and contextually define relevant categories of prosocial behaviors and the demographics and individual characteristics associated with such prosocial behaviors, in Uganda. There are three major reasons that motivate why this research is much needed:
Firstly, this research will aim to define prosocial behaviors in the context of Uganda and demonstrate methods to capture and categorize them, both of which have currently been defined by Western research. We seek to understand the variations in the way people perceive and engage in prosocial behaviors in an under-researched context and contribute our results to the existing body of literature.
Second, this research will further explore how individual characteristics (both demographics and psychographic) are associated with different contextualized categories of prosocial behaviors. Existing research has largely explored demographic links to some extent but has overlooked the link between other individual differences to the level of engagement with prosocial behaviors.
Finally, the results from the proposed research will have far-reaching impacts for social and community development, including but not limited to community-based groups, as well as researchers, practitioners, and policymakers. Our research can be easily used to guide the design and framing of communication to encourage engagement in prosocial behavior that promote community development and improve welfare.
 Uganda 2020-12-08 2023-12-08 Social Science and Humanities Non-degree Award
Daniel  Kaye Kabonge
ID:
COUNTRY-WIDE ESTIMATES OF THE INCIDENCE OF ABORTION AND ABORTION-RELATED MORBIDITY IN UGANDA
REFNo: HS1074ES

To systematically generate reliable nationwide evidence on the scale and distribution of the burden of unsafe abortion in Uganda and its effects, so as to engage policy and decision makers through further discussion of the subject in a amore contextualized manner. Specifically, to establish the incidence and distribution of unsafe abortion in Uganda, to estimate the effects of the burden of unsafe abortion in Uganda (in terms of magnitude of abortion complications) and to provide recommendations for decision makers on future programming for abortion care in Uganda
 Uganda 2020-12-08 2023-12-08 Medical and Health Sciences Non-degree Award
Laban Musinguzi Kashaija
ID: UNCST-2020-R014407
 The Situation of, and Impact of COVID-19 on school going girls and young women in Uganda
REFNo: SS676ES

The study will be guided by five specific objectives, which include the following;
1. Prevalence estimate of early marriages and adolescent pregnancies among school going girls during the Covid-19 pandemic in Uganda.
2. Describe the drivers of sexual engagement among school going girls during the Covid-19 pandemic.
3. Assess the level of participation of school going girls in available learning opportunities and their continued interest in education during the pandemic and the post-Covid-19 period.
4. Examine the involvement of school going girls in economic activities during the Covid-19 pandemic and the effects of this on the lives of school going girls.
5. Identify possible innovations to support girls to continue with education during the COVID-19 Pandemic and in the aftermath of the pandemic.

Uganda 2020-12-04 2023-12-04 Social Science and Humanities Non-degree Award
Richard Nyeko
ID: UNCST-2021-R012815
 Prognostic factors, Clinical outcomes and Survival among childhood cancer patients in northern Uganda: a five-year retrospective review of records
REFNo: HS884ES

General objective
To determine the prognostic factors, clinical outcomes and survival among children with cancer in northern Uganda treated in a low resourced non-specialized upcountry cancer treatment centre over a five year period from January 2014 to December 2018
Specific objectives
1. To determine the outcomes of children with cancer in northern Uganda treated at St. Mary’s hospital Lacor from January 2014 to December 2018
2. To establish the 1- and 2-year survival rates of children with cancer in northern Uganda treated at St. Mary’s hospital Lacor from January 2014 to December 2018
3. To determine the predictors of outcomes among children with cancer in northern Uganda treated at St. Mary’s hospital Lacor from January 2014 to December 2018

 Uganda 2020-12-03 2023-12-03 Medical and Health Sciences Non-degree Award
ANNETTEE NAKIMULI OLIVIA
ID: UNCST-2022-R011194
 Early pregnancy predictors of pre-eclampsia and its adverse outcomes in Uganda: a prospective cohort study at a busy peri-urban hospital
REFNo: HS918ES

1) To determine the exposures (epidemiological, clinical, laboratory) linked to pre-eclampsia and its adverse outcomes.
2) To determine the positive predictive value of screening using biomarkers (soluble Flt-1 and placental growth factor) and serial ultrasound for pre-eclampsia and its adverse outcomes.
3) To generate a resource of data and biological samples to facilitate hypothesis driven and discovery based approaches to identifying novel predictors and/or mechanisms of pre-eclampsia.

Uganda 2020-12-03 2023-12-03 Medical and Health Sciences Non-degree Award
Emanuele Colonnelli
ID:
INFORMATION FRICTIONS IN GOVERNMENT-FIRM RELATIONSHIPS
REFNo: SS606ES

The broad objective of our research is to provide the first comprehensive
understanding of the market for government contracts in a LIC country, with an emphasis on understanding what are the main challenges to the participation of firms to the procurement process and to the competitiveness and efficiency of public procurement.
 Italy 2020-12-03 2023-12-03 Social Science and Humanities Non-degree Award
GRACE MBABAZI
ID:
HIV AND PSYCHIATRIC DISORDERS IN UGANDA A Narrative exploration of lived experiences of HIV positive in- patients that develop comorbid Psychiatric disorders in Uganda, A Psychoanalytic Psychotherapeutic Perspective
REFNo: HS614ES

Aim and objectives
The proposed study intended to explore the lived experiences of people with HIV infection who develop psychiatric disorders using a psychotherapeutic approach. To fulfil this aim, the following objectives will be met:
• Explore the experiences of people with HIV and co-morbid psychiatric diagnoses
• Understand the lived experiences through a psychotherapeutic perspective
• Establish the key challenges facing this patient group and implications of these findings for future research

UK 2020-12-02 2023-12-02 Medical and Health Sciences Degree Award
Peter Akera Akera
ID:
ORAL HEALTH AMONG PRIMARY SCHOOL CHILDREN IN RURAL AND URBAN AREAS IN GULU DISTRICT, NORTHERN UGANDA
REFNo: HS700ES

1. To determine oral health knowledge, attitudes and behaviors among children (11-13 years).
2. To describe the current oral health status of children (11-13 years).
3. To explore schoolteacher’s perceptions and knowledge in relation to oral health, risk factors, and their contribution in health promotion.
4. To explore the oral health promotion experiences in schools among leaders, stakeholders and policy makers.

 Uganda 2020-12-02 2023-12-02 Medical and Health Sciences Degree Award
Stephen  Cose Christopher
ID: UNCST-2020-R015824
 A TB Postmortem Study
REFNo: HS703ES

• To determine the drivers of consent and decline for post mortem procedures and for donation of tissues for medical research
• To undertake postmortem procedures within 8 hours of death
• To determine cell viability and correlate this with time from death
• To undertake flow cytometry and cell stimulation studies to Identify phenotype, function and frequency of TB specific cells within tissues and blood of deceased patients
• To understand the tissue architecture and cell subset organization of cells involved and uninvolved tissues using new imaging techniques.


 UK 2020-12-02 2023-12-02 Medical and Health Sciences Non-degree Award
Robert Ssemulende
ID:
Situating the Sangoan techno-complex into Stone Age context at Sango Bay Southern Uganda
REFNo: SS530ES

i. To examine the typological and technological characteristics of the Sangoan lithic
industry
ii. To establish whether the Sangoan techno-complex is situated within the Acheulean,
Middle Stone Age or an independent industry.
iii. To investigate the environmental conditions under which the Sangoan existed.
iv. To establish the chronological sequence of the Sangoan industry from the type site at
Sango Bay
 Uganda 2020-12-02 2023-12-02 Social Science and Humanities Degree Award
EVERD  BIKAITWOHA MANIPLE FALUKU
ID:
ASSESSING THE PROPHYLACTIC ACTIVITY, SAFETY AND ECONOMIC IMPACT OF ARTAVOL® AGAINST MALARIA BURDEN AT HOUSEHOLD LEVEL IN APAC DISTRICT, UGANDA
REFNo: HS904ES

General Objective
To evaluate the impact of ARTAVOL on malaria burden at household level in Apac district in Northern Uganda.
Specific Objectives
1.To determine the Prophylactic effect of ARTAVOL against clinical malaria episodes in households.
2.To evaluate the safety profile of ARTAVOL when taken as a prophylactic against malaria.
3.To determine the reduction of malaria parasitemia in the population using ARTAVOL..
4To establish the reduction in malaria treatment cost among household on ARTAVOL beverage
5.To evaluate school attendance among school going children on ARTAVOL at household

Uganda 2020-12-02 2023-12-02 Medical and Health Sciences Non-degree Award
Mary Goretti Nakabugo Goretti
ID: UNCST-2021-R013051
 Assessment of Young People’s Literacy and Numeracy Competencies Required in the Workplace and Everyday Life in Uganda
REFNo: SS612ES

i) To provide evidence on young people’s literacy and numeracy competences required in the workplace and everyday life and their relationships with educational attainment and socio-economic characteristics.
ii) To contribute to the range of assessment approaches available in Uganda specifically aimed at informing policy.

 Uganda 2020-12-02 2023-12-02 Social Science and Humanities Non-degree Award
Moses Joloba Lutaakome
ID: UNCST-2022-R011558
 Accuracy of Novel Diagnostic Tests for Detection of Tuberculosis in Adults: FEND for TB (“FEND-TB Adults”)
REFNo: HS1016ES

Primary Objectives
• To provide clinical specimens and data to FEND for TB researchers and their collaborators in order to determine the diagnostic accuracy and operating characteristics of investigational in vitro tuberculosis diagnostic assays and strategies
• For each participant, to conduct a pre-specified set of standard-of-care diagnostic tests in order to classify that participant’s status with respect to tuberculosis (reference standard).

Secondary:
• To gather parameter estimates for economic analyses

Uganda 2020-12-02 2023-12-02 Medical and Health Sciences Non-degree Award
Waiswa Peter
ID: UNCST-2020-R014921
 Optimizing approaches to implementing self-injection of DMPA-SC within the contraceptive method mix: a case of Uganda
REFNo: HS1087ES

AIM: The aim of the study is to optimize approaches to implementing self-injection of DMPA-SC among various contraceptive choices and answer crucial questions about whether SI can enable contraceptive use for women who face barriers and enhance empowerment in Uganda.
4.1 Objectives:
1. Identify who may be the most likely to benefit from the scale-up of DMPA-SC self-injection.
2. Develop effective approaches for supporting the use of DMPA-SC self-injection in a way that helps women overcome barriers and optimize facilitators to contraceptive decision-making and use.
3. Understand the role self-injection can play in promoting empowered contraceptive decision-making and autonomy.
NB: SPECIFIC OBJECTIVES OUTLINED BELOW FORM PHASE ONE OF THE STUDY AND FOCUSES ON OBJECTIVE 1.
4.11 Specific objectives for Phase one:
I. To elucidate the barriers and facilitators to contraceptive decision-making and use among different groups (including identification of groups who face the most barriers), and identification of women with the most interest in SI across study sites of Mayuge and Oyam districts in Uganda.
II. To better understand the context within which DMPA-SC is being rolled out and identify where opportunities lie to conduct research into women’s interest and experience with the method alongside implementation efforts.


 Uganda 2020-12-02 2023-12-02 Medical and Health Sciences Non-degree Award
Rhoda Wanyenze
ID: UNCST-2021-R013352
 Understand the impact of COVID-19 on the ability of women to access family planning services and products in Uganda
REFNo: HS1031ES

1) To track the utilization of RH/FP and MNCH services including antenatal care (ANC) and postnatal care (PNC)
2) To describe the availability of supplies, commodities and human resources for these services
3) To document innovations and adaptations that the government of Uganda (GOU) and NGOs are implementing to ensure the continuity of services

 Uganda 2020-12-01 2023-12-01 Medical and Health Sciences Non-degree Award
Julie Abimanyi-Ochom Abimanyi-Ochom
ID:
IMPACT OF COVID-19 SOCIAL DISTANCING MEASURES ON LIVELIHOODS, HEALTH AND LIFESTYLES STUDY (CIS) IN SUB-SAHARAN AFRICA AND AUSTRALIA
REFNo: SS526ES

The study aims to generate knowledge on the impact of COVID-19 social distancing measures on livelihoods, food security, health, family conflict and lifestyle changes. The study has three main objectives: 1. To describe the extent of application of social distancing measures in select countries. 2. To assess the choice of social distancing measures in select countries and the impact on the different outcome measures – livelihoods, food security, health, family conflict and lifestyle changes. 3. To identify areas most affected by choice of social distancing measures and make recommendations for future recurrent COVID-19 waves or similar pandemics.
Uganda 2020-11-30 2023-11-30 Social Science and Humanities Non-degree Award
Noble Banadda
ID:
FOOD and Local, Agricultural, and Nutritional Diversity
REFNo: A95ES

To develop, implement, and validate innovative, scalable, and sustainable technologies aimed at supporting the nutrition performance of local food systems in Africa, while strengthening agro-biodiversity and food diversity as well as diversity of healthy diets
 Uganda 2020-11-30 2023-11-30 Agricultural Sciences Non-degree Award
CHARLES BENSTONS IBINGIRA RUKAMBURA
ID: UNCST-2021-R008521
 Determination and characterisation of viral load and antibody profiles in samples from multiple sites of COVID-19 patients in Uganda
REFNo: HS1035ES

4 Study Objectives
This study will aim to determine viral load and antibody production / levels in diverse samples from COVID-19 patients.
Specific aims:
1. Determine and compare virus levels in blood, saliva, naso/oro-pharyngeal swabs, urine, and stool of COVID-19 patients.
2. Determine and compare antibody levels (IgM, IgG & IgA) in blood, saliva, naso/oro-pharyngeal swabs, urine, and stool of COVID-19 patients.
3. Determine and assess neutralising antibody (IgG & IgA) activity (in plasma, naso-phargygeal, saliva samples respectively) from COVID-19 patients.

 Uganda 2020-11-30 2023-11-30 Medical and Health Sciences Non-degree Award
Atukunda  Gilbert
ID: UNCST-2020-R014643
 Analysis of Workplace Practices of Educational Leadership and Management Graduates of Aga Khan University-IED, EA in Uganda.
REFNo: SS559ES

The objective of the study is to examine how Educational Leadership and Management graduates of Aga Khan University-IED, EA have transformed their workplace practices using the knowledge and skills obtained from the course.
 Uganda 2020-11-27 2023-11-27 Social Science and Humanities Degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
 An Evaluation of the Pediatric Discharge Process following Hospital Admission with Sepsis/Severe Infection in Uganda
REFNo: HS928ES

The primary objective of this study is to evaluate the typical pediatric discharge process at a representative sample of hospitals in Uganda. The study will be guided by the following specific objectives.
Specially we intend to:
1. To assess the readiness of health facilities in providing minimum standard discharge care.
2. To assess health workers practices in the discharge care processes
3. To determine health worker perceptions of the quality of discharge processes.
4. To explore patient caregiver perceptions of the quality of discharge care experienced while their child was treated at the health facility.

 Uganda 2020-11-27 2023-11-27 Medical and Health Sciences Non-degree Award
Anthony  Batte
ID: UNCST-2022-R011127
 Prevalence of hypertension, HIV and Hepatitis B among participants of the world kidney day 2020 health screening in western Uganda (HHH Study)
REFNo: HS978ES

1. To describe the prevalence of hypertension, HIV and hepatitis B among participants of the world kidney day 2020 health screening in western Uganda
2. To evaluate the predictors of hypertension, HIV and hepatitis B among participants of the world kidney day 2020 health screening in western Uganda

 Uganda 2020-11-27 2023-11-27 Medical and Health Sciences Non-degree Award
Emmanuel Kaggwa Henry
ID:
PEDAGOGICAL LEADERSHIP APPROACHES, LEARNING ENVIRONMENT AND ACADEMIC PERFORMANCE OF STUDENTS IN SECONDARY SCHOOLS: A CASE STUDY OF NAKASEKE DISTRICT-UGANDA
REFNo: SS627ES

1. To assess the state of academic performance of students in the secondary schools of Nakaseke district.
2. To establish the correlation between pedagogical leadership approaches and academic performance of students in Nakaseke district.

3. To examine the influence of learning environment on academic performance of students in Nakaseke district.

4. To establish a new, effective and practical pedagogical leadership approach that will enhance academic performance of students in Nakaseke district.
Uganda 2020-11-27 2023-11-27 Social Science and Humanities Degree Award
William Buwembo
ID: UNCST-2022-R009661
 Anti-COVID-19 immunoglobulins G and M in blood specimens collected before lockdown at two urban clinics of Kampala, Uganda
REFNo: HS995ES

1. To determine the COVID-19 specific sero-prevalence at two urban clinics of Kampala, Uganda.
2. To determine the quality of virus specific antibody IgG in seropositive specimens
 Uganda 2020-11-27 2023-11-27 Medical and Health Sciences Non-degree Award
Peter Olupot-Olupot Olupot
ID: UNCST-2020-R014798
 Feasibility and Effectiveness of the National Research Information Management Systems (NRIMS) in Uganda; a Nested study within the Scaling up of capacity of Research Ethics Committees in Uganda (SCRECU).
REFNo: HS1052ES

Main Objective. To assess the feasibility and effectiveness of the National Research Information Management System (NRIMS) for effective Research Ethics Committee (REC) review process, facilitate multiple REC review, national registration and subsequent monitoring of approvals in Uganda. Specific. To assess the feasibility and effectiveness of NRIMS for review, registration and monitoring of research in Uganda. 2. To evaluate the cost economics of implementation of NRIMS.
 Uganda 2020-11-27 2023-11-27 Medical and Health Sciences Non-degree Award
Joseph Ochieng
ID:
Ethical and social issues for COVID-19 vaccine access in Uganda
REFNo: HS1101ES

The goal of the proposed study is to assess stakeholders’ awareness of ethical and social issues as well as perceptions of priority setting for COVID-19 vaccine accessto stimulate debate in preparation for COVID-19 vaccine and development of a model approach to priority setting in a Ugandan setting.

Aim 1. Assess stakeholders’ awareness of ethical considerations and social issues associated with COVID-19 vaccine access in Uganda
Aim 2. Assess stakeholders’ perceptions on ethical and social issues associated with priority setting for COVID-19 vaccine access in Uganda
Aim 3. Evaluate existing policies and guidelines on priority setting for COVID-19 vaccine access in Uganda
Aim 4. Develop a model approach to priority setting for COVID-19 vaccine access in Uganda

 Uganda 2020-11-27 2023-11-27 Medical and Health Sciences Non-degree Award
Grace Brown
ID:
Sustainable Coffee Farming: Agricultural Growth, Cultural Shift, and Its Direct Effect on Decreased Gorilla/Human Disease Transmission
REFNo: NS87ES

To record the influence of local agricultural shifts on the health of gorilla group populations within Bwindi.
-Record diseases and illnesses through fecal sample that are linked to some sort of human interaction, whether it be direct or through livestock.
-Determine how coffee farmers perspectives on gorilla conservation have changed, if at all, with their participation in Gorilla Conservation Coffee.
-Study how farmers with steadier incomes can better support sustainability and conservation efforts within Bwindi Impenetrable National Forest.

USA 2020-11-26 2023-11-26 Natural Sciences Non-degree Award
Claire Akwongo Julie
ID:
Prevalence, Risk factors of exposure and Socio-Economic impact of Peste des Petits Ruminants (PPR) in Karenga District, Karamoja Region, Uganda
REFNo: A71ES

1. Determine the sero-prevalence of anti-SRM in goats and sheep in Karenga District using the Competitive Enzyme-linked Immunosorbent assay. 2. Determine the socio-economic impact of PPR amongst communities in Karenga using participatory epidemiology. 3. Establish the risk factors associated with the occurrence and spread of PPR in Karenga District using participatory epidemiology.
Uganda 2020-11-26 2023-11-26 Agricultural Sciences Degree Award
Chris Opesen C
ID:
EXPLORING THE PHILANTHROPY PRACTICE IN UGANDA
REFNo: SS471ES

The overall objective of this study is to explore the landscape for and of philanthropy in Uganda. The study has the following specific objectives:

I.To conduct a legal and policy analysis for philanthropy in Uganda including tax laws. Expected outputs
II.To identify local philanthropic initiatives in the five (5) districts of Kampala, Mbarara, Gulu, Arua and Masaka.
III.To establish the factors that enhance and hinder local philanthropy.
IV.Lastly, to develop recommendations for strengthening philanthropic practice in Uganda, as well as emerging research areas.

 Uganda 2020-11-26 2023-11-26 Social Science and Humanities Non-degree Award
Esther Buregyeya
ID: UNCST-2020-R014116
 Promoting hand hygiene through use of locally-produced alcohol based handrub in health facilities in Wakiso District-Uganda
REFNo: HS817ES

i) To develop a behavioral intervention to foster hand hygiene compliance using locally produced alcohol handrub in HCFs in Uganda.
ii) To assess the acceptability, feasibility and effect of locally-produced alcohol handrub on HH compliance among health care workers in primary health care facilities, Uganda.
(ii) To assess the cost of fostering HH through use of locally-produced
alcohol-based hand-rub.

 Uganda 2020-11-26 2023-11-26 Medical and Health Sciences Non-degree Award
PAUL MBAGO
ID:
Bovine mastitis on selected farms in Kamwenge District: Prevalence and antibiograms of the associated bacteria
REFNo: A86ES

To determine the prevalence of bovine mastitis, antibiograms of associated bacteria and investigate presence of MecA and TetM resistance genes on selected farms in Kamwenge District.
 Uganda 2020-11-26 2023-11-26 Agricultural Sciences Degree Award
Agabirwe Patience
ID:
INFORMATION PRACTICES OF STUDENTS WITH VISUAL IMPAIRMENT IN PUBLIC UNIVERSITY LIBRARIES IN UGANDA USING DIGITAL INFORMATION RESOURCES
REFNo: SIR49ES

To explore the information practices of students with visual impairment (SWVI) as they seek, access and use Digital information resources (DIRs) in public University libraries and therefore propose strategies to improve the utilization of DIRs by SWVI in University libraries of Uganda.
 Uganda 2020-11-26 2023-11-26 Engineering and Technology Degree Award
Lina Sara Mathew Alonga Sara Mathew
ID:
Safety Profiling of Traditional Antimalaria Plant, Aristolochia bracteolata Lam. Commonly used among Communities of Jubek State, South Sudan
REFNo: HS851ES

i. To document the preparation methods, uses and effects of A. bracteolata antimalarial plant among the communities in Jubek State,
ii. To identify and quantify the levels of aristolochic acid in A. bracteolata and in preparation as used by the communities in South Sudan,
iii. To determine the general toxicity and nephrotoxicity of A. bracteolata community preparation using Laboratory animal models

 South Sudan 2020-11-26 2023-11-26 Medical and Health Sciences Degree Award
owino ambrose
ID:
“Exploration of mathematics teachers’ pedagogical content knowledge for teaching subtraction strategy: A case study in Kwania District, Uganda”
REFNo: SS554ES

The purpose of this study is to explore mathematics teachers’ pedagogical content knowledge for teaching subtraction strategies.
 Uganda 2020-11-26 2023-11-26 Social Science and Humanities Degree Award
Richard Mugambe Kibirango
ID:
The impact of an mhealth and environmental cues intervention on hand hygiene practice among healthcare workers in the greater Kampala metropolitan area. A cluster randomised trial.
REFNo: HS882ES

1. To explore the opportunities for enhancing healthcare workers’ hand hygiene practices in HCFs in the GKMA.
2. To explore the barriers for enhancing healthcare workers’ hand hygiene practices in HCFs in the GKMA.
3. To compare the impact of mobile phone WASH text messages with that of environmental cues on hand hygiene practice among health workers in HCFs in the GKMA.

 Uganda 2020-11-26 2023-11-26 Medical and Health Sciences Non-degree Award
Emma Ariyo S
ID:
Examination of Sociocultural Boundaries and Gender construction in Women’s Rugby in Uganda
REFNo: SS579ES

1. Contributing to the body of literature on women rugby players’ use of sport to navigate socio-cultural structures in society.

2. Providing an in-depth understanding of how female participation in sport impacts multiple identities [relations] and relationships [social positioning] in reference to young women and their families and communities.

3. Inform educators, activists, policy makers and sport administrators’ decisions about developing sport opportunities for women in Uganda.
Uganda 2020-11-26 2023-11-26 Social Science and Humanities Degree Award
Edith Akankwasa
ID:
Implementing a child disability prevention, detection and rehabilitation project in central Uganda: Learning and experiences from the field
REFNo: HS896ES

i. To establish if amongst the intervention districts, those districts that show stronger implementation of birth defect and child disability prevention, child disability detection, management and rehabilitation interventions as envisaged perform better on key birth defect detection and child disability rehabilitation indicators compared to those intervention districts with “a lower level of implementation” (i.e., evidence of “dose-response”).
ii. To determine if, after three years, districts in project overall intervention area will show more improvement in coverage from baseline on key birth defect and child disability prevention, disability detection, management and rehabilitation indicators compared with those districts in the comparison area.
iii. To appraise the processes used in enhancing the delivery of the birth defect and child disability prevention, detection and rehabilitation services where they are being implemented.
iv. To explain in detail how and why the strategies employed led to the observed coverage in access to and utilization of the CDR project services in the implementation districts.
v. To characterize the stakeholders for birth defect and child disability prevention, detection and rehabilitation services.
vi. To document the barriers and facilitators used in the implementation of the CDR project along with how the barriers can be addressed

 Uganda 2020-11-26 2023-11-26 Medical and Health Sciences Non-degree Award
WINTERS MUTTAMBA
ID:
Exacerbation of Chronic Bronchial Sepsis (ECBS): A study of the role of key bacteria in exacerbations of COPD and bronchiectasis
REFNo: HS921ES

SECONDARY OBJECTIVES
i. To compare bacterial loads at presentation with time to first exacerbation.
ii. To assess the relationship of bacterial loads of specific bacteria with emergency attendance.
iii. To compare bacterial loads at presentation with time-to-clinical-stability (TCS), CRP response and length of antibiotics.
iv. To assess the relationship of specific bacterial loads with quality of life (QoL) scores.
v. To assess the microbiome dynamics during- and after- treatment.

EXPLORATORY OBJECTIVES
1. To compare bacterial loads with Bronchiectasis Severity Index (BSI) in those with a clinical diagnosis of bronchiectasis.
2. To compare admission bacterial loads with baseline FEV for relationship with key clinical outcomes.
3. To compare key clinical outcomes based upon initial counts of neutrophils, lymphocytes, platelets and eosinophils, and their ratios (including principally neutrophil-lymphocyte ratio, NLR, and platelet-lymphocyte ratio, PLR).
4. To compare bacterial loads with bronchiectasis severity index (BSI) in those with a clinical diagnosis of bronchiectasis.


 Uganda 2020-11-26 2023-11-26 Medical and Health Sciences Non-degree Award
Elizeus Rutebemberwa
ID: UNCST-2022-R009070
 Reducing Tobacco use among the In- and Out-of-School youths in Moroto district, Uganda
REFNo: HS1021ES

General objective:
The general objective is to assess tobacco use among the youth in Moroto district.

Specific objectives:
1)Explore perceptions of tobacco use among youth in and out of school in Moroto district

2)Determine the factors associated with tobacco use among youth in and out of school in Moroto district

3)Describe the perceptions regarding tobacco use among the school teachers and administrators

4)Explore the cultural role that tobacco use plays in the lives of the youth in Moroto district.

5)Assess adherence to the tobacco control Act within bars and restaurants in Moroto district.

6)Assess youth access to tobacco in Moroto district.

7)Describe the perception of the implementation of tobacco control activities in Moroto district by enforcement officers.

 Uganda 2020-11-26 2023-11-26 Medical and Health Sciences Non-degree Award
Shaheen Memon Mohamed Zahiruddin
ID:
APPLICATION OF MACHINE LEARNING TECHNIQUES TO ANTENATAL ATTENDANCE, MATERNAL MORBIDITY AND FETAL OUTCOMES IN UGANDA
REFNo: HS977ES

1. Establish the factors associated with the number of ANC visits by a pregnant woman who experiences SMM in Uganda.
2. Examine the factors associated with severe maternal morbidity as experienced by pregnant women in Uganda.
3. Assess the maternal factors associated with negative fetal outcomes in Uganda.

Kenya 2020-11-26 2023-11-26 Medical and Health Sciences Degree Award
Harriet Opondo
ID: UNCST-2022-R010927
 Counselors’ Experiences of HIV Status Disclosure to Children living with HIV in Uganda
REFNo: SS626ES

-To explore subjective experiences of counselors during the process of status disclosure to children living with HIV
-To find out how counselors are prepared and trained to conduct status disclosure to children living with HIV.
-To establish the current interventions used by counselors in HIV disclosure process to children.
-To find out self-identified training needs of counselors during and after status disclosure to children living with HIV.

 Uganda 2020-11-26 2023-11-26 Social Science and Humanities Degree Award
Fred Ssewamala
ID: UNCST-2020-R014060
 Suubi4Stigma: Addressing HIV-Associated Stigma Among Adolescents
REFNo: SS632ES

Suubi4Stigma will address the urgent need for theoretically and empirically informed interventions that seek to reduce HIV/AIDS-associated stigma and its negative impact on child health and psychosocial well-being. Specifically, the proposed study will examine two evidence-based interventions used in mental health settings, schools, and communities: 1) group cognitive behavior therapy (G-CBT) focused on cognitive restructuring and strengthening coping skills at the individual level; and 2) a multiple family group (MFG) intervention that strengthens family relationships to address stigma among CLWH and their families.

Aim 1: Pilot test the feasibility, acceptability, and preliminary impact of innovative G-CBT and MFG on reducing HIV/AIDS-associated (internalized and family-level) stigma and its’ impact on youth and family-level outcomes (stigma, trauma symptoms, depression, sexual risk, family/social support and adherence to medication) compared to: 1a) usual care vs G-CBT; b) Usual care vs MFG; c) G-CBT vs. MFG;

Aim 2: Qualitatively examine participants’ and facilitators’ intervention experiences and identify individual, family and institutional-level facilitators and barriers to G-CBT and MFG intervention implementation and participation.

Uganda 2020-11-26 2023-11-26 Social Science and Humanities Non-degree Award
Joseph Oloro
ID: UNCST-2024-R004525
 Toxicological study of the antimalarial remedy (Artavol®) and its flavonoid isolate from artemesia annua
REFNo: HS540ES

To determine acute toxicity of Artavol® and of its isolated flavonoids
ii. To investigate the sub-acute and sub-chronic toxicity potential of Artavol® and of its isolated flavonoids.
iii. To evaluate the effects of Artavol® and of its isolated flavonoids on the fetus.
iv. To examine the mutagenic potential of Artavol® and of its isolated flavonoids.

 Uganda 2020-11-25 2023-11-25 Medical and Health Sciences Degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 Characteristics of persons screened, tested and diagnosed with corona virus disease-19 at health facilities in Uganda
REFNo: HS657ES

Main objective:
To estimate the cumulative incidence of a composite treatment outcome of admission to intensive care unit, mechanical ventilation or death among COVID-19 confirmed patients attending health facilities in Uganda for COVID-19 care.

Secondary objectives:
1. To describe the socio-demographic, behavioral and clinical characteristics of patients screened for and or receiving COVID-19 care at health facilities in Uganda
2. To determine the screening and testing outcomes of COVID-19 infections among patients at health facilities in Uganda

 Uganda 2020-11-25 2023-11-25 Medical and Health Sciences Non-degree Award
Jafesi Pulle
ID: UNCST-2020-R014213
 DECENTRALIZATION OF BENZATHINE PENICILLIN G BEST PRACTICES: BUILDING THE TOOLS FOR A SUSTAINABLE AND SCALABLE PROGRAM
REFNo: HS835ES

(1) Develop materials that can be used across Uganda and East Africa to strengthen BPG administration skills in the health worker community,
(2) Test this package of materials in Lira and Mbarara, areas with high BPG demands, and
(3) Evaluate the immediate and 3-month results of the educational program on proper BPG delivery, health worker comfort, and patient satisfaction.

Uganda 2020-11-25 2023-11-25 Medical and Health Sciences Degree Award
Firminus  Mugumya
ID:
Measuring the Impact and Sustainability of a Community-Based Child Protection Approach in Prevention of Violence Against Children in a Post Conflict Setting in Northern Uganda.
REFNo: SS566ES

The overall question for this evaluation is: What is the impact and sustainability of interventions to strengthen community-based child protection systems on prevention of violence against children in families and communities emerging from a protracted armed conflict?

The specific questions are:
•Does training Child Protection stakeholders result into functional community-based Child Protection systems for prevention of violence against children?
•Does an equipping child protection structure with knowledge, skills, financial and material resources on case management improve access to child protection services?
•Does legislation and dissemination of relevant child protection laws lead to improved implementation and enforcement for prevention of violence against children?
•Does equipping children with knowledge and skills in child protection, make them indispensable change agents for addressing violence against children?
•What evidence exists to show that the project interventions to prevent violence against children at family and community level in post-conflict setting will be sustainable?
•What are the critical enablers of project success, and what should be avoided for future similar interventions in and out of post-conflict settings?
•How sustainable are interventions interventions to strengthen community-based child protection systems?

 Uganda 2020-11-25 2023-11-25 Social Science and Humanities Non-degree Award
Ronald Mulondo Mulondo
ID:
Spatiotempoaral Characterization of Congenital Myelomeningocele in Uganda
REFNo: HS763ES

1.To provide a basic description of the MMC dataset at CURE Hospital, characterizing the geographical and temporal distribution.
2.To examine whether the incidence of MMC in Uganda is non-uniform or not.
3.To examine the association between MMC case incidence and rainfall.

 Uganda 2020-11-24 2023-11-24 Medical and Health Sciences Degree Award
Benjamin Atwine
ID:
Knowledge and risk factors of Hepatitis B disease among women attending Antenantal Care ate Arua Regional Referral Hospital, Uganda.
REFNo: HS785ES

General Objective
To determine the level of available knowledge and risk factors associated with Hepatitis B disease among pregnant women attending ANC at ARRH.
Specific Objective
1. To determine the percentage of women attending ANC at ARRH who are knowledgeable about Hepatitis B disease.
2. To determine the prevalence of Hepatitis B disease among pregnant women attending ANC at ARRH who take part in the study.
3. To determine the risk factors of Hepatitis B disease among pregnant women seeking ANC at ARRH.
 Uganda 2020-11-24 2023-11-24 Medical and Health Sciences Degree Award
Kenneth Ssebambulidde Ssebambulidde
ID: UNCST-2021-R013976
 Collection of control DNA samples for the AMBITION-cm host-susceptibility to cryptococcal infection sub-study (a genome wide association study). A sub-study of the AMBITION-cm Trial
REFNo: HS789ES

To identify genetic variants associated with Cryptococcal meningitis susceptibility and disease severity
 Uganda 2020-11-24 2023-11-24 Medical and Health Sciences Non-degree Award
Paul  Kutyabami
ID: UNCST-2020-R015029
 THE EFFECT OF COVID-19 OUTBREAK ON ONGOING RESEARCH PROCESSES IN UGANDA: KEY STAKEHOLDER’S EXPERIENCES, OPINIONS AND COPING STRATEGIES
REFNo: HS910ES

1.To explore the experiences of key stakeholders involved in research during Covid-19 outbreak in Uganda
2.To explore opinions and strategies regarding conduct of research during epidemic outbreaks in Uganda.

 Uganda 2020-11-24 2023-11-24 Medical and Health Sciences Non-degree Award
Viola Karungi
ID:
Critical Theatre: An Analysis of Plays Representing the concepts of Violence, Injustice and the nature of Imperialism in regard to the War (1987-2006) in Northern Uganda.
REFNo: SS605ES

The major research question for the study is:
i. How do the plays Silent Voices, Forgotten World and Forged in Fire about the war in northern Uganda contribute to understanding the role of contemporary critical theatre in light of Uganda’s history of critical theatre?
The sub-questions are:
i. How do the plays represent the concept of violence on victims of the war in northern Uganda?
ii. How do the plays expose the nature of imperialism by the donor countries and institutions from the West that gave donor and humanitarian aid during the war and in its immediate aftermath?
iii. How do the plays represent the concept of injustice and how it is shaped by violence and imperialism regarding the war in northern Uganda?


Uganda 2020-11-23 2023-11-23 Social Science and Humanities Degree Award
Stella Neema
ID: UNCST-2019-R000814
 Evaluation of UNICEF’s District Health Systems Strengthening Initiative (DHSSi) – Uganda Study Protocol
REFNo: SS613ES

The overall objectives of the evaluation are twofold:
• To improve intervention design and management, and
• To inform decisions about future investment and scale-up by establishing evidence of the results and impact of the intervention.
These overall objectives are further broken down into specific objectives:
• Assess whether interventions were implemented according to the work plan and measure the strength of the implementation.
• Examine district health governance and management capacity.
• Identify key lessons learned and provide actionable and evidence-based recommendations for improvements and scale-up.

 Uganda 2020-11-23 2023-11-23 Social Science and Humanities Non-degree Award
DOROTHY NAKIMBUGWE NAKIMBUGWE
ID:
Impact of COVID19 lock down and, effectiveness of supplementary feeding on the nutrition status of mothers and their malnourished breastfeeding children, attending nutrition Units of health facilities in Kampala and Wakiso – a pilot study to inform national and organizational policies and interventions
REFNo: HS984ES

a) Assess the impact of the COVID19 lockdown and social distancing requirements on the nutrition status of mothers of children attending nutrition clinics at health centers and their access to food in Kampala and Wakiso districts through individual interviews using a semi-structured questionnaire.
b) Determine the effectiveness of a locally produced nutrient-enhanced composite porridge flour for improving the nutrition status of mothers and their breastfed malnourished children.
 Uganda 2020-11-23 2023-11-23 Medical and Health Sciences Non-degree Award
DAVID KATEETE PATRICK
ID: UNCST-2020-R004018
 Insight into the Role of the Microbiome in Pulmonary tuberculosis in Kampala, Uganda (MTI-Plus)
REFNo: HS738ES

The overall purpose of this proposal is to determine the composition of the microbiome in pulmonary TB patients in Kampala Uganda, and its relationship with TB treatment response and immune response relative to household healthy contacts without TB and HIV-infection. In context of treatment naïve adult TB patients, we will (1) (a) Examine the relationship between sputum and gut microbiome diversity and disease. (b) Investigate the relationship between sputum and gut microbiome composition and treatment response in patients on first-line TB therapy, and whether dysbiosis resolves in patients who get cured from TB after successfully completing anti-TB therapy. (2). Investigate the relationship between sputum and gut microbiome composition and inflammatory cytokine production capacity.
Uganda 2020-11-20 2023-11-20 Medical and Health Sciences Non-degree Award
Chioma Adeyemi Njideka
ID:
Phytochemical and Abortifacient Studies of Commelina benghalensis in Wister Rats
REFNo: SS576ES

The specific objectives of this study are;
a) To profile the phytochemical groups in C. benghalensis L in rats.
b) To determine the acute toxic dose of leaves and stalk extracts of C. benghalensis L in rats.
c) To investigate the abortifacient activities of leaves and stalk extracts of C. benghalensis L in rats.
d) To evaluate the sub-acute effect of the plant extract showing more abortifacient activity in wistar rats.

 Nigeria 2020-11-20 2023-11-20 Social Science and Humanities Degree Award
Barbara Mukasa
ID:
Baseline, Midterm and End of Project Evaluation Protocol for Mildmay Mubende Region
REFNo: SS639ES

(i) Systemize baseline, midterm and end of project evaluations including interim analyses for Mubende region service delivery implementing mechanism supported by CDC Uganda.
(ii) Closely monitor the progress of outputs as measured by Monitoring Evaluation and Reporting (MER) indicators arising from implementation of activities and conduct periodic program evaluations to determine the funded activities will achieve outcomes that ultimately reduce HIV incidence and AIDS

 Uganda 2020-11-20 2023-11-20 Social Science and Humanities Non-degree Award
Paul  Kutyabami
ID: UNCST-2020-R015029
 Assessing the impact of the requirements for dual- licensing guidelines on the number of drug outlets and compliance to regulation
REFNo: HS1048ES

-To determine the trends in the number of pharmacies licensed as both retail and wholesale from 2016 to 2020 in NDA regions
-To establish the level of compliance of pharmacies previously dual-licensed as of 2016 to set requirements of their current license
-To explore the possible factors other than guidelines associated with a decline in the license application for pharmacies that have had dual licensure
-To determine the effect of dual licensing guidelines on access to medicines in underserved areas

 Uganda 2020-11-20 2023-11-20 Medical and Health Sciences Non-degree Award
Winnifred Kansiime Kimara
ID: UNCST-2021-R012131
 Predictors of indoor air quality in Kisenyi-Mugunu a slum settlement in Fort Portal Municipality, Uganda
REFNo: HS695ES

General objective
To assess predictors of indoor air quality so as to promote the health of children under five dwelling in Kisenyi-Mugunu, Fort Portal Municipality.
Specific objectives
1. To determine the level of IAQ in Kisenyi-Mugunu, Fort Portal Municipality.
2. To establish the predictors of IAQ in Kisenyi-Mugunu, Fort Portal Municipality.
3. To explore the barriers and facilitators to uptake of healthier household energy options in Kisenyi-Mugunu.

 Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Jackson Orem
ID: UNCST-2021-R012016
 Characterizing Determinants of Primary KSHV Infection among Children and Adolescents in Uganda
REFNo: HS735ES

1. To determine the incidence and to define the viral, immunologic, and clinical features of primary KSHV infection.
2. To identify the biologic and behavioral risk factors associated with primary KSHV infection.
3. To develop mathematical models that characterize KSHV shedding dynamics and virologic drivers required for transmission.

 Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Irene Andia Biraro Rebecca
ID: UNCST-2019-R001475
 Machine Learning and Secondary Data Analyses of the RASHOTS Database to Guide Clinical Decision Making and Predict Patient Prognosis at Kiruddu National Referral Hospital, Uganda
REFNo: HS745ES

The primary project objectives are:
1. To utilise ML methods to estimate the risk of mortality on the ID wards at Kiruddu National Referral Hospitals using the RASHOTS medical database
2. To develop prognosis prediction scores for survival on the ID wards using ML methods on the RASHOTS medical database based on clinical prognostic factors

The secondary project objectives are:
1. To estimate the prevalence of major mortality drivers such as tuberculosis, tetanus using the RASHOTS medical database
2. To create a prognosis prediction protocol for risk of tuberculosis related mortality as a computer application for use by clinicians on ID wards
3. To use the RASHOTS database for quality improvement in clinical care and practice in the department of Internal Medicine

Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Annette Namugaya Mugabe Jane
ID: UNCST-2020-R014795
 TRENDS AND INDICATIONS FOR CAESAREAN SECTION IN MBALE REGIONAL REFERRAL HOSPITAL A CROSS SECTIONAL STUDY
REFNo: HS777ES

General Objective
To determine the trends and indications for caesarean section delivery in MRRH (Eastern Uganda) during the study period (July 2013 to June 2018)

Specific Objectives
1. To determine the trend for caesarean section in MRRH (Eastern Uganda) over the study period
2. To identify the indications for CS delivery in MRRH (Eastern Uganda) over the study period

 Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Degree Award
Peter Rukundo Milton
ID: UNCST-2020-R014799
 Next Generation Nutrition in Uganda: Enhancing Dietary Intake of Iron and Folic Acid in a Culturally Acceptable Food Product for Pregnant Women to Improve Maternal and Child Outcomes
REFNo: HS828ES

Evaluate the effect of the innovative product on the health outcomes of the infants at birth,Investigate the efficacy of this innovative product to reduce iron and folic acid deficiency in pregnant women.,Develop a culturally acceptable and quality assured iron bio-fortified beans and silverfish pre-cooked instant sauce fortified with iron and folic acid to meet nutritional needs for pregnancy.,
 Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Irene Andia Biraro Rebecca
ID: UNCST-2019-R001475
 The Trends in Clinical Presentation and Management of Diseases among Adults attending Kiruddu National Referral Hospital, Kampala: Review of Medical Records.
REFNo: HS1030ES

General objective
To analyse medical records for trends in presentation and management of disease conditions in the in-patient department (IPD) and out-patient department (OPD) at KNRH from 2019 to date.
Specific objectives
I. To describe trends of respiratory disease presentation and clinical management among adult patients presenting to the IPD, medical and general OPD at KNRH during the study period (January to July 2020) compared to the baseline period (January to July 2019)
II. To explore for any collateral effects of the global SARS-CoV-2 pandemic on chronic disease presentation and management at KNRH during the same study period.

 Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Waiswa Peter
ID: UNCST-2020-R014921
 AN ASSESSMENT OF THE IMPACT OF COVID-19 ON RMNCAH AND HIV SERVICE DELIVERY AND UTILIZATION IN UGANDA
REFNo: HS1084ES

1. To document the response actions for mitigating the impact of COVID-19 on RMNCAH and HIV services at national, sub-national, health facility and community levels
2. To assess the district, health facility and community preparedness to provide RMNCAH and HIV services during the pandemic.
3. To obtain information on the implications of COVID-19 on the level of access and utilization of routine RMNCAH, HIV and other health services
4. To explore the effects of COVID-19 pandemic on mental health, intimate partner violence and gender roles
5. To assess the effects of COVID-19 on early child development, food security, feeding practices and nutrition among children under five years.
6. To generate recommendations for informing future national policy and public health response to health emergencies

 Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Bonnie Fournier
ID: UNCST-2019-R000250
 Reducing HIV-related Stigma in School Children
REFNo: HS510ES

Specific research objectives:
● Objective 1: To assess the magnitude of change, among young people who receive the arts-based intervention, in measures of stigma (i.e., enacted, internal, anticipated, courtesy, and perceived), HIV knowledge and attitudes towards young people who are HIV+ and –affected;
● Objective 2: To assess the intervention effect on HIV testing behavior among HIV-negative sexually-active young people;
● Objective 3: To assess the intervention effect on linkage to care, initiation of Antiretroviral Therapy (ART), and adherence to ART among HIV+ young people;
● Objective 4: To evaluate how, and under what circumstances, the intervention had an effect.

 Canada 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Imelda Bates
ID:
Development of a complex quality improvement intervention for timely blood transfusions for the management of postpartum haemorrhage (PPH) in Uganda
REFNo: HS579ES

1. To map out active transfusing facilities and blood centres in two districts in Uganda and create a profile of baseline measures of quality of PPH management and blood transfusion services (e.g. availability of blood, safety of blood, timeliness of referrals of women with PPH, regular measurement of haemoglobin in PPH patients) for each district
2. To determine key barriers to the appropriate management of PPH, including blood transfusion
3. To gain stakeholder buy-in and contribution to a lead-on quality improvement intervention’s design from all levels, with a specific view to feasibility and sustainability
 UK 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Alison Elliott
ID: UNCST-2023-R006524
 “Establishing a Single-Sex Controlled Human Schistosoma mansoni Infection Model for Uganda: Safety and Dose Finding” (CHI-S-Ug1)
REFNo: HS697ES

Primary objective: To investigate (1) the safety and tolerability and (2) the infectivity of male Schistosoma mansoni (Sm) cercariae in healthy adult Ugandan volunteers with (a) minimal prior exposure to Sm, and (b) intense prior exposure to Sm.
Exploratory objectives: To investigate the kinetics of controlled infection with male Schistosoma mansoni cercariae in healthy adult Ugandan volunteers (a) with minimal prior exposure to Sm, and (b) with intense prior exposure to Sm. To investigate immunological, metabolic and microbiome changes after infection with Schistosoma mansoni male cercariae. To investigate volunteer and wider community understandings of CHI in the context of CHI-S.


UK 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Adegbola Tololupe Adesogan Carola
ID:
FEED THE FUTURE PESTE DES PETITS RUMINANTS VACCINE ASSOCIATE AWARD
REFNo: A77ES

In the course of the pilots, the project will conduct: • A rapid assessment of existing information and surveillance activities to identify the most relevant actions to reinforce surveillance and epidemiological assessments capacity and information. • At least one training workshop to enhance skills and establish epidemiological monitoring systems that meet both disease control and project applied research needs. • Targeted sero-sampling designed for the estimation of the basic reproductive number. • Participation in the investigation of outbreaks and facilitation of the collection of material for viral isolation and genomic analysis. • Mapping of virus flows and modeling of disease transmission as an approach to integrating data from diverse sources. • Areas targeted will be points of high virus circulation and will have substantial levels of PPR antibody; the project will measure the impact of vaccination on herd immunity and the frequency of disease events.
USA 2020-11-17 2023-11-17 Agricultural Sciences Non-degree Award
John  Ssempebwa
ID: UNCST-2020-R014966
 ASSESSMENT OF STATUS AND DEVELOPMENT OF FRAMEWORK AND GUIDELINES TO IMPROVE HEALTH AND SAFETY OF SWIMMING POOLS IN THE GREATER KAMPALA METROPOLITAN AREA, UGANDA
REFNo: HS730ES

Objectives
1. To determine the physio-chemical and microbiological quality of water in swimming pools.
2. To determine the knowledge, and practices of swimmers and operators regarding safety of
swimming pools.
3. To establish the hygienic and safety status at the swimming pools premises.
4. To establish a framework and guidelines to regulate operation of swimming pools in Uganda.
 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Jonathan Nsamba
ID: UNCST-2024-R003888
 Body composition and muscular health of children and adolescents diagnosed with type 1 diabetes mellitus in Uganda
REFNo: HS759ES

1. To determine the body composition of children and adolescents diagnosed with T1DM as compared to their closely matched sex and age controls.
2. To determine the hand grip strength of children and adolescents diagnosed with T1DM as compared to their closely matched sex and age controls.
3. To examine the associations between dietary intake patterns, physical activity, nutrition status and body composition among children and adolescents diagnosed with T1DM
4. To understand the perceptions of newly diagnosed Type 1 Diabetes Mellitus children and adolescents about their disease status, barriers and facilitators to self-care.

Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Degree Award
FADHIL GERIGA
ID: UNCST-2022-R011524
 Optimizing Nephroblastoma treatment outcomes in Uganda
REFNo: HS822ES

Primary Objectives:
o To determine the one-year survival of children with pathology confirmed nephroblastoma treated with multidisciplinary, stage-based care in Uganda.
o Assess the factors associated with morbidity and mortality among children with nephroblastoma.

Secondary Objectives:
o Characterize the frequency and spectrum of other malignancies that present similar to Nephroblastoma
o Characterize the social needs and health literacy of nephroblastoma patients and their caregivers at the UCI
o Assess quality measures of a multidisciplinary care, including:
- Treatment timing benchmarks following guidelines developed for UCI
- Adherence to treatment plan and elimination of loss to follow-up
o Assess social needs and provide a patient navigator for families of children with nephroblastoma and reduce the non-clinical barriers to care for children with nephroblastoma

Exploratory Objectives:
o To collect plasma for future studies evaluating circulating tumor DNA as a tool for diagnosis of pediatric kidney cancers and monitoring of patients with nephroblastoma.
o Collect stool specimens for future studies to define baseline factors in the stool microbiome that are associated with neutropenic fevers, sepsis and 12 months survival using combination of sequencing methods and stool ova and parasites evaluation.
 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Christine Nalwadda Kayemba
ID: UNCST-2020-R014220
 EXPLORING CHILDREN’S UNDERSTANDING OF COVID-19 AND ITS PREVENTIVE STRATEGIES IN UGANDA: A CROSS SECTIONAL STUDY AMONG CHILDREN AGED 10-13 YEARS IN HOIMA DISTRICT
REFNo: HS830ES

General objective

To explore children’s understanding of COVID-19 disease and related preventive measures, in order to generate information that will guide the development of evidence-based strategies for strengthening and improving children safety and wellbeing during and after the COVID-19 crisis.

Specific objectives

1.To establish the children’s knowledge of COVID-19 transmission and its preventative measures in Hoima Municipal Council

2.To describe how the COVID-19 preventative measures are understood and practiced by children aged 10 to 13 years in Hoima Municipal Council

3.To explore the enablers for the recommended health measures for the prevention of COVID -19 among children aged 10 to 13 years in Hoima Municipal Council

4.To explore the barriers for the recommended health measures for the prevention of COVID -19 among children aged 10 to 13 years in Hoima Municipal Council

 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Doreen Nakimuli
ID: UNCST-2021-R013668
 Formative Study to Understand Drivers and Barriers to Uptake of Permanent Methods of Family Planning Among Men and Women in Busoga Sub region
REFNo: HS862ES

The overall objective is to understand the factors that influence women, men and providers in Busoga region during the journey to access PMs to enable PSIU to design interventions.
Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
NAUME MUYANGA
ID:
UNDERSTANDING THE IMPACT OF GENDER BASED VIOLENCE ON HIV/AIDS PREVENTION AND TREATMENT HEALTH SEEKING BEHAVIORS AMONG TRANSWOMEN IN THE GREATER KAMPALA METROPOLITAN AREA, UGANDA.
REFNo: SS557ES

Broad objective:
To understand the impact of gender-based violence on HIV/AIDS prevention and treatment seeking behaviors among the transwomen in the greater Kampala metropolitan area, Specific objectives:
1. To document the lived gender-based violence experiences among the transwomen in the greater Kampala metropolitan area, Uganda.
2. To explore the existing gender-based violence referral pathways used by the transwomen in the greater Kampala metropolitan area, Uganda.
3. To explore the impacts of gender-based violence on HIV/AIDS prevention and treatment seeking behaviors among the transwomen in the greater Kampala metropolitan area, Uganda.
4. To identify priority issues for advocacy and programming in prevention and response to gender-based violence among the transwomen in the greater Kampala metropolitan area, Uganda.

 Uganda 2020-11-17 2023-11-17 Social Science and Humanities Non-degree Award
Susanna (Zanna) Clay
ID:
The origins of empathy- Investigating empathy development in the first two years of life
REFNo: SS596ES

Empathy – the sharing and understanding others’ emotions and thoughts – is an essential part of what it means to be human. While empathy underpins our most meaningful social interactions, we lack knowledge about its developmental and evolutionary origins. Thus far, research on empathy development remains limited, something which may have led to inaccurate conclusions that infants lack the capacity for empathy before their second year.. Although the view that infants lack empathy has recently been challenged, current research remains constrained by a lack of research attention as well as suitable methodologies to study early empathy. A key goal of this project is to address these limitations by conducting the first major study of empathy development across the first 2 years of life. By combining observations with novel experimental techniques our goal is study how the cognitive and affective components of empathy emerge.

Another objective is to investigate the impact that the social and cultural environment have on infant socio-emotional development. Research indicates that caregiving and the socio-cultural environment shape infant development, however, there is little research looking into how these factors shape empathy development. In addition, most developmental research so far has been conducted on infants from Western societies, also denoted as WEIRD (Western Educated Industrialised Rich Democratic) whilst ignoring cross-cultural variability. By focusing on a subset of Western societies, current developmental research is thus not representative of global diversity; ignoring insights from cross-cultural variation may lead to inaccurate interpretations.

In order to address this and understand how the socio-cultural environment shapes empathy development, it is essential to study how empathy develops in a more diverse cross-cultural sample. Through doing so, we can also address which aspects of empathy may be learned or socially-mediated, and which might reflect human universals. The current project aims to address this by studying the development of empathy and the influence of the socio-cultural environment. The capacity for empathy has far reaching consequences for how we function as a species and interact with others. A lack of capacity to care about others (empathy) can have many negative consequences for individuals and our societies, including reduced wellbeing, quality of social relationships, crime and mental health. Given the importance of empathy for our social and societal functioning, it is essential to know where empathy comes from and how it is shaped by social and cultural experiences.

This project represents a continuation and extension of the research activities of a current and approved research project, led by Professor Katie Slocombe, running on infant development in the Masindi district of Uganda. This project was approved by UNCST and UVRI (UVRI-045/2017). Our current project uses very similar methods and is planned to be conducted with the same local research assistants and communities who have participated in this research.

UK 2020-11-17 2023-11-17 Social Science and Humanities Degree Award
Kenneth Katumba Rogers
ID:
Developing a country-specific EQ-5D-5L value set and an inequality parameter for Uganda
REFNo: SS597ES

The primary objective of this study is to develop an EQ-5D value set for Uganda,

secondary objectives are:
● To explore the feasibility of a ‘lite’ valuation protocol in the LMIC setting
● To elicit a health inequality aversion parameter for Uganda
 Uganda 2020-11-17 2023-11-17 Social Science and Humanities Non-degree Award
Doreen Nakimuli
ID: UNCST-2021-R013668
 Understanding Self Injection of DMPA-SC: Provider Research Uganda 2020
REFNo: HS938ES

The study is aimed at gaining a deep understanding of the consumer and health care provider journey is critically important to the introduction of family planning products into new districts. through answering the following questions:
1. What is the value proposition of self-inject for them?
2. What would increase their level of trust in women’s ability to successfully self-inject?
3. What would enable them to support consumers on the self-injection journey?
o What would be included in an optimal consumer initial training experience?
o What factors would support them to provide ongoing support for consumers who inject at home and experience side-effects?
o How could they better help consumers overcome barriers to access, including ensuring stock of DPMA-SC for client’s re-supply of product?
4. What factors would optimize provider training for self-injection?
o How could training be more convenient, effective, and of higher perceived value?
o What are the opportunities and barriers to using digital channels to learn and attend training on self-inject?
o What are the opportunities and barriers to using digital channels to train and support clients in using self-inject?

 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
 Theoretical analysis of the pediatric discharge process in Uganda: A process evaluation
REFNo: HS929ES

The primary objective of this study is to build a theoretical model of the current pediatric discharge pathway from the time of admission until post-discharge follow-up.
 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
DAVID KATEETE PATRICK
ID: UNCST-2020-R004018
 Co-infection of SARS-CoV-2 with M. tuberculosis & other respiratory pathogens (SARS-CoV-2-
REFNo: HS940ES

(1) Estimate the prevalence of coinfection of SARS-CoV-2 with other respiratory pathogens, (2) Investigate the impact of coinfections on molecular testing for COVID-19 infection and, (3) Apply metagenomics whole genome sequencing for unbiased detection of respiratory pathogens directly in respiratory samples
 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Dinah Amongin
ID: UNCST-2020-R014663
 Rapid Assessment of COVID-19 Impact on Family Planning Access and Use
REFNo: HS952ES

1. Document the proportion of Viamo 3-2-1 users who have their demand for family planning satisfied by modern methods during the pandemic and the recovery process;
2. Measure the proportion of current modern contraceptive users who have obtained their preferred contraceptive method among women who initiated or resupplied their method during the pandemic and the recovery process;
3. Describe barriers in accessing family planning services to ensure voluntary method use and choice during the pandemic and the recovery process.

 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Patrick Kagurusi Tumusiime
ID: UNCST-2021-R012687
 International Registry of Healthcare Workers Exposed to COVID-19 Patients (UNITY Global) at Selected Health facilities in Uganda
REFNo: HS964ES

Primary Objective
To assess the association of potential prophylactic treatments with reduced risk of COVID-19 (or SARS-CoV-2 infection) in HCWs caring for COVID-19 patients at selected health facilities in Uganda.

Secondary objectives
i) To characterize the type of potential prophylactic treatments, by dose and duration, overall, and by region and or selected health facilities (sites) in Uganda.
ii) To explore the key factors (for example, use of PPE, HCW and healthcare facility characteristics, underlying co-morbidities, household history and COVID-19 exposure) modifying the risk of COVID-19 among HCWs at selected health facilities (sites) in Uganda.

 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Margaret Lubwama
ID: UNCST-2019-R000636
 Antibacterial activity of Rosmarinus officinalis L. and Curcuma longa against bacteria from clinical specimens in Uganda- A therapeutic option for multidrug resistant bacteria (ARC study)
REFNo: NS141ES

Main objective
To determine the activities of Rosmarinus officinalis L. (rosemary) and Curcuma longa (turmeric) extracts against bacteria isolated from clinical specimens at the Makerere University Microbiology Clinical Laboratory (MUCML) from January 2018 to December 2019

Specific objectives
1. To develop the chemical composition of Rosmarinus officinalis L. (rosemary) and Curcuma longa (turmeric) extracts
2. To determine the Minimum Inhibitory Concentration of plant extracts from Rosmarinus officinalis L. (rosemary) and Curcuma longa (turmeric) against bacteria isolated from clinical specimens
3. To determine the synergistic effects of combination of Rosmarinus officinalis L. (rosemary) and Curcuma longa (turmeric) and antibiotics against bacteria isolated from clinical specimens in the MUCML
Uganda 2020-11-17 2023-11-17 Natural Sciences Non-degree Award
Wenceslaus Sseguya
ID: UNCST-2019-R000877
 The Effect COVID-19 Pandemic on the Management and Control of Diabetes in Patients Receiving Support from a Life for a Child-Supported Diabetes Program in Kasese District, Western Uganda
REFNo: HS987ES

• To describe problems and challenges experienced by patients with insulin-requiring diabetes during the COVID-19 pandemic.
• To explore personal experiences of health workers and primary caregivers regarding diabetes management and control of patients with insulin-requiring diabetes during the COVID-19 pandemic.
• To document mechanisms used to solve problems and overcome challenges encountered by patients with insulin-requiring diabetes, caregivers and health workers during the COVID-19 pandemic.
• To describe the perceived support needs for patients with insulin-requiring diabetes during the COVID-19 pandemic period and post the COVID-19 period.

 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Andrew Mujugira
ID: UNCST-2019-R000871
 Interventions for Improved Post-partum ART Continuation and HIV Testing of Male Partners of Women in PMTCT B+ in Uganda
REFNo: HS991ES

Aim 1: To evaluate whether the proportion of male partners of pregnant HIV-positive women who test for HIV, is improved after distribution of a letter of invitation to a wellness visit (dual syphilis and HIV rapid test, blood pressure, visual acuity screening and COVID-19 screening) to their female partners compared to the standard of care (standard of care invitation letter from the clinic).

Aim 2: To evaluate whether POC viral load testing with same day ART adherence support improves viral suppression among pregnant and post-partum women living with HIV compared to standard of care lab-based HIV VL testing.

Aim 3: To assess the proportion of HIV-negative male partners who initiate PrEP and HIV positive men who initiate ART among male partners who test for HIV through a wellness visit or standard of care letter from the clinic.

Aim 4: To evaluate acceptability and preferences for HIV testing and other health services among pregnant women and male partners using mixed methods.
 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Namulema Edith
ID:
EARLY RESUMPTION OF SEXUAL INTERCOURSE IN THE PUERPERIUM AMONG MOTHERS IN UGANDA: BURDEN AND THE EFFECT OF HEALTH EDUCATION ON PUERPERAL ABSTINENCE
REFNo: HS1050ES

1)To establish the burden and factors associated with of early resumption of sexual intercourse within the puerperium (ERSP) among new mothers in Kawempe National Referral Hospital (Kawempe NRH) and Mengo Hospital.
2)To explore the perceptions, attitudes, experiences and actions towards the ERSP among new mothers and their partners in Kawempe NRH and Mengo Hospital.
3)To explore how health care workers in Kawempe NRH and Mengo Hospital perceive the level of puerperal sexual health care services provided to couples with new babies.
4)To identify strategies that may delay the early resumption of sexual intercourse among new mothers at Kawempe NRH and Mengo Hospital and design an appropriate psycho-sexual educational intervention to reduce ERSP.
5)To evaluate the effect of psycho-sexual health educational intervention on reducing ERSP among couples with new babies at Kawempe NRH and Mengo Hospital.

 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Degree Award
Joseph Musaazi
ID:
USING ROUTINELY COLLECTED SECONDARY DATA TO ESTIMATE UPTAKE AND EFFECT OF ISONIAZID PREVENTIVE THERAPY ON TUBERCULOSIS INCIDENCE AND PREGNANCY OUTCOMES AMONG PEOPLE LIVING WITH HIV RECEIVING CARE IN PUBLIC HEALTH FACILITIES IN UGANDA.
REFNo: HS729ES

1) To determine trends of IPT uptake and completion rates among PLHIV receiving HIV care at public health facilities in Uganda.
2) To determine the effect of IPT on TB incidence among PLHIV receiving care at public health facilities in Uganda.
3) To estimate the effect of IPT on pregnancy outcomes among women living with HIV (WLHIV) receiving care at public health facilities in Uganda.

 Uganda 2020-11-16 2023-11-16 Medical and Health Sciences Non-degree Award
Jamila Nansimbe
ID:
UNDERSTANDING THE MEDICAL SUPPLY CHAIN BOTTLENECKS IN THE PUBLIC HEALTH SECTOR IN UGANDA (CASE OF KAMPALA CAPITAL CITY AUTHORITY HEALTH CENTERS)
REFNo: HS939ES

1. To examine the main causes of stock-outs of medicine and health supplies.

2. To examine the main causes of expiry of medicines and health supplies.

3. To recommend supply chain interventions to improve availability of medicines and health supplies.

 Uganda 2020-11-13 2023-11-13 Medical and Health Sciences Non-degree Award
Cissy  Kityo
ID: UNCST-2021-R013663
 A5372: Drug-Drug Interactions Between Rifapentine and Dolutegravir in HIV/LTBI Co-Infected Individuals
REFNo: HS624ES

Primary Objectives;

-To determine the dosing for DTG that, when given together with 1HP, achieves target exposures (Ctrough) of standard-dose DTG when it is given without RPT.
-To estimate the steady state plasma pharmacokinetics (PK) of DTG when DTG 50 mg is dosed twice daily (BID) with 1HP.
-If Arm 2 opens, to estimate the steady state plasma PK of DTG when DTG 50 mg is dosed once daily (QD) with 1HP.

Secondary Objectives;

-To evaluate the safety of coadministration of DTG based ART with 1HP.
-To evaluate the tolerability of coadministaration of DTG based ART with 1HP
-To estimate the proportion of participants who maintain virologic suppression when DTG based ART is coadministered with 1HP

 Uganda 2020-11-12 2023-11-12 Medical and Health Sciences Non-degree Award
Pauline Amuge Mary
ID:
Community-based initiation and delivery of isoniazid preventive therapy (IPT) among household TB contacts in Uganda: A pilot project in Southwestern Uganda. Short Title: Community-Based TB prevention (Acronym: COMBAT TB).
REFNo: HS768ES

Primary Objective:
To assess the uptake of IPT among household TB contacts <5 years of age receiving IPT in the community delivery approach.

Specific Objectives:
1. To determine IPT completion rates among household TB contacts <5years of age enrolled in community-based delivery approach compared to those in the health facility-based IPT delivery approach.
2. To identify the factors that facilitate or hinder IPT uptake in the community-based delivery for household TB contacts <5years of age.

3. To determine the feasibility of community-based IPT delivery for household TB contacts <5years of age.
4. To determine the factors that facilitate or hinder IPT completion among household TB contacts <5years of age who initiate IPT.


 Uganda 2020-11-12 2023-11-12 Medical and Health Sciences Non-degree Award
Denis Kyabaggu Senkandwa
ID: UNCST-2023-R005881
 INFLUENCE OF SP110 POLYMORPHISMS IN HUMAN MACROPHAGES ON PULMONARY TUBERCULOSIS DISEASE AMONG UGANDANS
REFNo: HS870ES

-To identify, using Next Generation DNA Sequencing (NGS) technology, the SP110 gene polymorphisms among adult Ugandan pulmonary tuberculosis (PTB) disease patients reporting to Mulago National Referral hospital TB clinic.
-To determine the effect of the commonest SP110 SNPs identified in Ugandans on in vitro infection kinetics of MTB as measured by confocal microscopy techniques, in human monocytic leukemia THP-1 macrophage tissue cultures.
-To determine the in vitro effect of the top 3 SP110 SNPs among Ugandans on infection kinetics of MTB lineages 2, 3, 4 and H37Rv isolates in human monocytic leukemia THP-1 macrophage tissue cultures using confocal microscopy.
-To determine the SP110 SNPs present among TB patients co-infected with HIV at Mulago National Referral Hospital TB clinic.
 Uganda 2020-11-12 2023-11-12 Medical and Health Sciences Degree Award
Rhoda Wanyenze
ID: UNCST-2021-R013352
 PILOT OF A NETWORK-DRIVEN, ADVOCACY INTERVENTION TO PROMOTE CERVICAL CANCER SCREENING IN UGANDA
REFNo: HS943ES

The proposed intervention development study seeks to improve cervical cancer screening in Uganda by engaging and training local public health researchers and program implementers, and empowering women living with cervical cancer risk (WLCCR), defined as women who have ever received treatment for pre-cancerous or cancerous lesions, to advocate for CC screening and early treatment among women in their social networks. Specifically, the study will aim to: 1. Assess the feasibility and acceptability of implementing a cervical cancer screening advocacy intervention with WLCCR, who will be trained to be advocates for CC screening and treatment behaviors in their social networks. 2. Assess preliminary intervention effects on the CC screening (primary outcome) and treatment behaviors of women in contact with the WLCCR advocates and diffusion of anti-stigma messages across social networks. 3. Explore characteristics of women who more effectively engage in screening advocacy (in terms of socio-demographics, network characteristics, and type of social network members receiving advocacy). 4. Increase capacity among local researchers and program implementers to conduct public health research on cervical cancer control and use social network-based intervention and measurement methods. The intervention will be implemented in three phases, and for each phase, we will seek ethical clearance and approval prior to data collection. At the moment, we are seeking ethical clearance for the first phase where we intend to conduct focus group discussions to obtain women's perceptions and suggestions about the intervention to inform the development of the intervention.
 Uganda 2020-11-12 2023-11-12 Medical and Health Sciences Non-degree Award
Amon Agaba
ID:
The quality and safety standards of herbal medicine production and vending in greater Mbarara District
REFNo: HS720ES

General Objective:
To document the adherence and practice required to maintain the quality and safety of herbal medicine production and vending in Mbarara District.

Specific Objectives:
I.To document the adherence to standard herbal medicine production guidelines by herbal medicine producers and vendors in Mbarara District
II.To explore the enablers and barriers to adherence to the recommended guidelines that govern the production and vending of herbal medicine in Mbarara District.

 Uganda 2020-11-11 2023-11-11 Medical and Health Sciences Non-degree Award
Josephine Nabukenya Kwagala
ID:
ASSESSING THE POTENTIAL FOR TRANSFORMING HEALTH IN UGANDA THROUGH AN ELECTRONIC HEALTH DATA SHARING PLATFORM AND DATA SCIENCE
REFNo: HS1005ES

General Objective:
To explore the readiness malaria and HIV as potential demonstrator conditions for an EHR data capturing and processing system infrastructure and analytical methods that could support Uganda’s Ministry of Health and related health institutions to provide responsive care and interventions based on real-time surveillance.

Specific Objectives:
Objective 1: To (a) develop a complete understanding of the routine care data currently captured and all surrounding dynamics including timing of capture by whom and how and what the current state of onward use is and (b) determine how these will influence data capture with electronic point of care capture systems.

Objective 2: To determine what technical, ethical/governance and workforce infrastructure are required for a timely model data capture system that addresses medical, public health and research needs of stakeholders.

Objective 3: In order to determine readiness, we will (a) model the cost of each proposal/ model system and determine on-going cost and potential cost recovery, including the cost of all other components (i.e., Buy-in, Timeliness, Capability) and determine what would be required to eliminate key barriers; and (b) map our data to EHR data capture and processing readiness frameworks.


Objective 4: To provide examples of cost effectiveness by determining how much additional malaria and/or HIV control would be required to offset the cost of the system over various time periods.

Uganda 2020-11-11 2023-11-11 Medical and Health Sciences Non-degree Award
Moses  Mulumba
ID: UNCST-2021-R013832
 National Study on the impact of contentious issues and masculinities on the realization of Sexual and Reproductive Health and Rights in Uganda
REFNo: SS537ES

General Objective: To generate evidence for SRHR advocacy and programming in Uganda
Specific objectives are;
1. To document the journey of the Sexual and Reproductive Health and Rights movements in Uganda
2. To explore the relationship between masculinities and sexual reproductive health and rights
3. To examine the influence of contentious issues like abortion, and LGBTQI on the realization of SRHR

 Uganda 2020-11-10 2023-11-10 Social Science and Humanities Non-degree Award
Robert Downing George
ID: UNCST-2020-R014615
 Evaluation of the Clinical Performance of a Plastic Capillary Tube with the Determine HIV-1/2, Determine HIV Early Detect and Determine HBsAg 2 Rapid Tests
REFNo: HS895ES

The primary objective of this study is to evaluate the performance of a new plastic capillary tube for the transfer of a capillary finger-stick blood sample to 3 rapid test platforms; the Determine HIV-1/2 test platform, the Determine HIV Early Detect test platform and the Determine HBsAg 2 platform. The HIV and HBsAg results obtained using the new plastic capillary tubes to transfer capillary whole blood to the test devices will be evaluated against the HIV and HBsAg results obtained using a micropipette to transfer a whole blood venous sample from the EDTA Vacutainer tube to the same testing platforms, with discrepant result resolution where required. The new plastic capillary tubes have been verified in an internal performance study at the Abbott laboratories.
 UK 2020-11-10 2023-11-10 Medical and Health Sciences Non-degree Award
Edward  Bitarakwate
ID:
Evaluation of Patient and Program Outcomes Achieved through EGPAF-supported Integrated HIV and TB Prevention, Care, and Treatment Programs in Uganda
REFNo: HS930ES

Primary Objectives:
1.To determine patient and program outcomes for children, adolescents and adults receiving HIV and TB services in EGPAF supported facilities and through EGPAF supported programs.

Secondary Objectives:
1. To determine outcomes of HIV testing strategies targeted at identifying HIV positive children, adolescents, and adults in facilities and the community including the number and proportion identified as HIV-positive, linked to HIV services, and initiated on ART in EGPAF supported facilities and through EGPAF supported programs.
a. To determine individual, population, and program characteristics/factors associated with each outcome along the testing to treatment cascade.

2. To determine clinical and laboratory outcomes among HIV-positive children, adolescents and adults enrolled in HIV services such as morbidity (including coinfections), mortality, ART regimen, ART adherence, retention in care, viral suppression, and disease progression in EGPAF supported facilities and through EGPAF supported programs.
a. To determine individual, population, and program characteristics/factors associated with each outcome, including baseline clinical characteristics before initiating ART.

3. To determine the outcomes of HIV prevention activities (including PMTCT) among pregnant women, discordant couples, adolescents and other key and priority populations in facilities and the community including the number accessing prevention services by risk category, retention in services, and seroconversion rates.
a. To determine individual, population, and program characteristics/factors associated with the HIV prevention outcomes.

4. To determine clinical and laboratory outcomes among children, adolescents and adults accessing TB screening/diagnosis, prevention, and treatment services such as HIV/TB coinfection rates, initiation and adherence to IPT, initiation and adherence to TB treatment, retention in care, treatment outcomes for drug resistant TB, mortality.
a. To determine individual, population, and program characteristics/factors associated with each outcome.

 Uganda 2020-11-10 2023-11-10 Medical and Health Sciences Non-degree Award
Harriet Mayanja-Kizza
ID: UNCST-2021-R013074
 “Assessment of circulating proteins in Ugandan tuberculosis household contacts for latent TB infection biomarker development: Version 1.0 dated 14 Sept 2020”
REFNo: HS958ES

Refine our protein signature to function in HIV-positive persons, incorporating cytokine and chemokine markers as needed.
2. Refine our protein signature to identify Mtb infection that has developed within a 6-month timeframe.

 Uganda 2020-11-10 2023-11-10 Medical and Health Sciences Non-degree Award
Esther Nanfuka Kalule
ID:
Livelihood Resilience During the COVID-19 Lockdown: Practices of Informal Sector Populations in the Urban and Peri-urban Settings of Kampala and Wakiso Districts
REFNo: SS619ES

The study will specifically:
• Examine the current livelihood practices and resources among urban informal sector workers in the context of restricted mobility and social distancing
• Examine the opportunities and challenges for vulnerable urban informal sector workers to negotiate and reconfigure livelihood sources including social networks and social capital for support in a lockdown situation
• Assess the most valued livelihood sources (assets, capabilities, activities) under the lockdown and preferred areas of allocating available resources among different categories of the informal urban population
• Examine the potential and perceived risks (including public health) of the livelihood activities undertaken during the COVID-19 lockdown

 Uganda 2020-11-10 2023-11-10 Social Science and Humanities Non-degree Award
ARTHUR  SEKIZIYIVU BRIAN
ID:
END-LINE EVALUATION OF AN HIV PREVENTION PROJECT IMPLEMENTED BY UGANDA PEOPLE’S DEFENSE FORCES AND PACE
REFNo: HS989ES

I. Measure changes in the knowledge, attitudes and practices among the military and AGYW to adopt and sustain positive behavior change.
II. Identify challenges, innovations, lessons, and success stories across the interventions
III. Identify the opportunities to integrate prevention interventions within (into) an HIV care program

 Uganda 2020-11-10 2023-11-10 Medical and Health Sciences Non-degree Award
Hannington Odongo Jawoko
ID: UNCST-2024-R002457
 The Relationship between Social Governance and Smallholder Farmer Socio-Economic Resilience: Moderating Effects of Pluralistic Agriculture Extension Service Provision in Northern Uganda
REFNo: A78ES

To investigate the moderating effects of perceptions of the quality of pluralistic agricultural extension services provision on social governance exhibited in participatory local government planning and budgeting process.

To examine the influence of social governance exhibited in participatory local government planning and budgeting process on the values and needs of smallholder farmers in northern Uganda.

To assess the impacts of perceptions of the quality of pluralistic agricultural extension services provision on socio-economic resilience of smallholder farmers in northern Uganda.

To examine the impacts of social governance exhibited in participatory local government planning and budgeting process on smallholder farmer’s socio-economic resilience in northern Uganda.

 Uganda 2020-11-09 2023-11-09 Agricultural Sciences Degree Award
Anthony Mugeere Buyinza
ID:
THE IMPRINT OF EDUCATION: A LONGITUDINAL COHORT STUDY OF AFRICAN ALUMNI OF THE MASTERCARD FOUNDATION SCHOLARS PROGRAM
REFNo: SS543ES

(i) To provide evidence at multiple levels on the individual, structural, contextual and programmatic factors that mediate Scholars’ outcomes especially with regards to “return”, “giving back”, “transformative and ethical leadership”

(ii) To assess the imprint of education on the lives of individuals, communities and societies in contexts such as those on the African continent in which Mastercard Foundation (MF) provides scholarships.

(iii) To examine the links between socio-economic inclusion, education and development.

(iv) To understand what works and why, as well as what might be done to improve the MSP and maximise the impact of Scholars as agents in the social and economic transformation of the African continent (by considering their social networks, support and training received, the way in which institutions contributed to their success, and their employment and employment creation trajectories).
 Uganda 2020-11-09 2023-11-09 Social Science and Humanities Non-degree Award
Augustine Ssevviri Kaddu Musisi
ID:
Using the Health Belief model to increase the level of knowledge, attitudes and practices of COVID-19 prevention measures in Wakiso district, Uganda
REFNo: HS883ES

1.0 Main Objective
To understand the level of adherence towards the COVID-19 guidelines and assess the knowledge and attitudes regarding COVID 19 in order design a behavioral change intervention that enhances knowledge and promotes compliance to the prescribed COVID-19 practices at the grassroots level in Wakiso district, Uganda
1.1 Specific Objectives
• To determine the level of knowledge about the prevention of COVID-19 among the people in Wakiso district
• To understand community attitudes towards the prevention of COVID-19 in Wakiso district
• To determine the level of adherence to COVID-19 prevention guidelines among community members in Wakiso District
• To design a behavioral change communication intervention for improving people’s knowledge, attitudes and level of adherence towards COVID-19 guidelines

Uganda 2020-11-09 2023-11-09 Medical and Health Sciences Non-degree Award
willy waninga
ID:
The use of ICT in the teaching of integrated science in Primary Teachers' Colleges in Uganda: A case of Four Primary Teachers' Colleges
REFNo: SS594ES

1. To find out ICT tools used by science tutors in teaching integrated science education
2. To find out how science tutors use technological content knowledge in planing integrated science education lessons.
3. To find out how integrated science education tutors integrate technological content knowledge in the pedagogy of science education.
 Uganda 2020-11-09 2023-11-09 Social Science and Humanities Degree Award
Herbert Kayiga Kayiga
ID:
IMPACT OF COVID-19 PANDEMIC ON MATERNAL AND NEWBORN HEALTHCARE SERVICE DELIVERY IN PRIVATE AND PUBLIC FACILITIES IN UGANDA
REFNo: HS924ES

STUDY OBJECTIVE:
To determine the impact of COVID-9 pandemic on the provision of maternal and newborn services in Kampala, Uganda

SPECIFIC OBJECTIVES:
1. To determine the quality of maternal and newborn service provision in Kampala, Uganda before the COVID-19 pandemic.
2. To determine the quality of maternal and newborn service provision in Kampala, Uganda during the COVID-19 pandemic.
3. To seek understanding of the experiences of the health workers as they provide maternal and newborn services in Kampala, Uganda.
4. To seek understanding of the pregnant and breastfeeding mothers’ experience as they seek maternal and newborn services in Kampala, Uganda.

 Uganda 2020-11-09 2023-11-09 Medical and Health Sciences Non-degree Award
Matthew  Cotten Louis
ID:
Local sequencing of SARS-CoV-2 from Uganda COVID-19 cases
REFNo: HS936ES

To document the transmission dynamics of COVID-19 in Uganda using full viral genome sequencing
 USA 2020-11-09 2023-11-09 Medical and Health Sciences Non-degree Award
Eve  Namisango
ID: UNCST-2021-R014038
 Title: Analysis of A Tool To Assess Psycho Social Spiritual Healing: Cognitive Interviewing
REFNo: HS957ES

1. To determine the face and content validity of the NIH-HEALS

2. To determine the comprehensiveness, comprehensibility and acceptability of the NIH HEALS in Uganda
 Uganda 2020-11-09 2023-11-09 Medical and Health Sciences Non-degree Award
Jane  Kabami
ID: UNCST-2021-R012588
 Leveraging the HIV platform for hypertension control in Uganda (INTEGRATED HIV/HTN)
REFNo: HS979ES

1 To determine the effectiveness of an integrated HIV/HTN care model on HTN and dual
HIV/HTN control among adult patients in HIV clinics.
2 To assess the barriers and facilitators of the integrated HIV/HTN care model for HIV
patients at different levels.
3 To determine the cost, cost-effectiveness and incremental gain costs of the integrated
HIV/Hypertension care model approach
 Uganda 2020-11-09 2023-11-09 Medical and Health Sciences Non-degree Award
Grace Edwards
ID:
An exploration of the need for Nursing and Midwifery Leadership Capacity Building in Uganda
REFNo: HS562ES

The study is aimed at exploring the leadership training needs for nurses and midwives in Uganda, in order to develop recommendations for developing nursing and midwifery leaders in Uganda and draft a leadership training programme.
 UK 2020-11-04 2023-11-04 Medical and Health Sciences Non-degree Award
Moses Adroma
ID: UNCST-2019-R000360
 INCIDENCE & PREDICTORS OF ABNORMAL RENAL FUNCTION THREE MONTHS AFTER DELIVERY AMONG PREECLAMPSIA SURVIVORS AT MULAGO HOSPITAL
REFNo: HS341ES

To determine the incidence and predictors of abnormal renal function three months after delivery among preeclampsia survivors at Mulago Hospital.
 Uganda 2020-11-04 2023-11-04 Medical and Health Sciences Degree Award
Kintu  Mugagga
ID:
Comparative Assessment of Anatomical and Neuro-Cognitive Characteristics Between Vaginally And Caesarean Section Delivered Children of 1-2 years Age At Mbarara Regional Referral Hospital, South-Western Uganda
REFNo: HS397ES

i) To describe the differences in the head-size and body height between VD and CSD children at 1-2 years of age born at Mbarara Regional Referral Hospital.


ii)To describe the differences in neurocognitive characteristics between VD and CSD children at 1-2 years of age born atMbarara Regional Referral Hospital.


iii)To describe the perinatal and socio-demographic characteristics of the mothers to the VD and CSD childrenof 1-2 years of age delivered at Mbarara Regional Referral Hospital.

 Uganda 2020-11-04 2023-11-04 Medical and Health Sciences Non-degree Award
Nelson Sewankambo K
ID: UNCST-2020-R014578
 Owning our future through community engagement: enhancing uptake of COVID-19 prevention and mitigation measures”
REFNo: HS858ES

Specific Objectives
1. Ascertain the:
a) Prevailing attitudes and perceptions towards COVID-19 mitigation measures and community response and adaptation (behaviours, practices) to the “new social norms” imposed by the emergency response;
b) Short-term socioeconomic impact and community coping mechanisms
2. Develop and implement a community engagement intervention for enhancing uptake of the recommended COVID-19 public health and social mitigation measures.
3. Evaluate the effects of the intervention developed in 2 above on acceptance and uptake of the COVID-19 prevention and mitigation measures.

Uganda 2020-11-04 2023-11-04 Medical and Health Sciences Non-degree Award
Martha Nabadda
ID:
A qualitative case study exploring health workers’ perspectives on facilitators and barriers to comprehensive management of sickle cell disease in young adults aged 18 – 25 years accessing primary care in Uganda.
REFNo: HS616ES

i. To investigate the facilitators and barriers to comprehensive management of sickle cell disease, using a focused group discussion and ten semi-structured, in-depth interviews with healthcare workers at three sickle cell clinics in Uganda.

ii. To explore the care and support needs specific to young adults with sickle cell disease accessing the health system at the point of primary care.

iii. To make care and policy recommendations for the Ministry of Health to improve guidelines for the provision of sickle cell disease care in public health facilities in Uganda.
 Uganda 2020-11-04 2023-11-04 Medical and Health Sciences Degree Award
Abner Tagoola
ID: UNCST-2021-R013446
 Enhancing maternal participation in neonatal hospital care using an adapted Family Integrated Care (FICare) program
REFNo: HS632ES

The purpose of this study is to adapt and test a model of enhanced maternal participation (FICare) in a neonatal hospital unit in Uganda. This is with the goal of increasing the level of patient monitoring and ultimately improving the quality of care that sick and small newborns receive in the hospital. Specifically, the study is
1. To determine the acceptability of implementing an adapted FICare model, specifically maternal assessment of newborn danger signs, weight and feeding, in a neonatal hospital unit in Uganda (Phase I)
2. To test the feasibility of implementing maternal assessment of newborn danger signs, weight and feeding, in a neonatal hospital unit in Uganda (Phase II)

 Uganda 2020-11-04 2023-11-04 Medical and Health Sciences Non-degree Award
Gorrette Nalwadda Kayondo
ID:
Analysis of Reproductive Maternal Newborn Child Adolescent Health Referral Pathways in Rural and Urban Health Care Settings in Uganda
REFNo: HS646ES

1. Examine the referral pathways relevant to RMNCAH from community level to the various health system levels that is HC II – IV, district and regional referral hospitals.
2. Explore the key challenges, lessons learnt and opportunities that enable or hinder RMNCAH referrals
3. Propose practical ways of improving the referral pathways for better RMNCAH service delivery outcomes in Uganda.

 Uganda 2020-11-04 2023-11-04 Medical and Health Sciences Non-degree Award
David Ayebare Santson
ID:
Factors Influencing Cervical Cancer Screening In Sheema District
REFNo: HS661ES

To identify the socio-demographic, cultural, and economic factors influencing low uptake of Cervical Cancer Screening services among women aged 25-49 years in Sheema district.
 Uganda 2020-11-04 2023-11-04 Medical and Health Sciences Non-degree Award
Lydia Nakiyingi
ID:
Effect of the COVID-19 situation on vulnerable HIV-infected and -affected adolescent girls and young women: A case of Kampala district
REFNo: HS746ES


General objective
• To determine the effect of the Uganda COVID-19 response on underprivileged HIV-infected and affected adolescent girls and young women with the aim is to develop relevant interventions, informed by their experiences, to address their actual needs.
Specific objectives:
• Document experiences of underprivileged HIV-infected and -affected adolescent girls and young women in Kampala during the COVID-19 period.
• Determine unmet needs of underprivileged HIV-infected and -affected adolescent girls and young women during the COVID-19 period.
• Assess perceptions of HIV-infected and affected adolescents towards the COVID-19 prevention interventions.
• Determine effects of the COVID-19 situation on physical, mental and psychosocial wellbeing of underprivileged HIV-infected and -affected adolescent girls and young women.
• Develop COVID-19 context-specific implementable recommendations (guided by the study’s findings) to inform interventions for underprivileged HIV-infected and -affected adolescent girls and young women.

 Uganda 2020-11-04 2023-11-04 Medical and Health Sciences Non-degree Award
Timothy  Muwonge Ronald
ID: UNCST-2020-R014680
 DIAL-COVID: Remote mitigation through telephone symptom surveillance in refugee settlements in Uganda
REFNo: HS901ES

The primary objective is to assess uptake and validate a mobile telephone surveillance and mitigation tool (“Dial-COVID”) in refugee settlements in Uganda.
The secondary objectives are:
1. To implement a mobile telephone interactive voice response (IVR) symptom tracker and information dissemination tool (“Dial-COVID”) and assess its uptake in the refugee population.
2. To iteratively test and validate a screening algorithm for COVID-19 using symptoms and risk factors reported by Dial-COVID users to predict infection determined by positive COVID-19 tests.
3. To assess COVID-19 risk perceptions and knowledge among refugees.
4. To understand barriers and facilitators to adoption of COVID-19 prevention and control measures in refugee settlements.
 Uganda 2020-11-04 2023-11-04 Medical and Health Sciences Non-degree Award
Sarah  Skeen
ID:
The Sharing Stories Project: Promoting playful parenting through sharing digital books in the COVID-19 era
REFNo: SS517ES

Relying on in-person book-sharing models, we will adapt this project to be deliverable over WhatsApp, and engage parents through sending digital books, holding weekly webinars, and sending individualized messages to support parents’ mental health and wellbeing. We will partner with the Regional Psychosocial Support Initiative (REPSSI) and the Africa Early Childhood Network (AfECN) to deliver this digital intervention to parents with young children with the aim to promote parenting through play, parental sensitivity, responsiveness and mental health, and child social, emotional and cognitive development.

South Africa 2020-11-04 2023-11-04 Social Science and Humanities Non-degree Award
SHEBA  NAKACUBO GITTA
ID:
How can UK Health Worker Volunteers Effectively and Sustainably Support the Development of Ugandan Health Workforce?
REFNo: HS837ES

1. To provide an overview of current approaches and priorities to health worker volunteer placements in Uganda;
2. To identify the priority needs for health worker volunteer placements in partnership with the Ministry of Health;
3. To give insight into the volume of health worker placements available and make recommendations on how such schemes can be designed to achieve mutual benefit for the UK, Uganda and other host countries.

 Uganda 2020-11-02 2023-11-02 Medical and Health Sciences Non-degree Award
Rhoda Wanyenze
ID: UNCST-2021-R013352
 Development of a community-led intervention to prevent and control unintended immediate socio-economic and health consequences of COVID-19 among slum dwellers in Kampala, Uganda 2020
REFNo: SS638ES

1. To assess the immediate socio-economic and health vulnerabilities due to COVID-19 among slum dwellers of Bwaise I and Bwaise III, in Kampala Uganda.
2. To explore predisposing factors to the vulnerabilities.
3. To determine the level of adherence and barriers to compliance with COVID-19 prevention measures.
4. Use the Human centred design (HCD) to explore and design potential interventions to reduce vulnerabilities and determine their feasibility.
5. To explore lessons for future policy and designing inclusive outbreak interventions for slum dwellers.

 Uganda 2020-10-29 2023-10-29 Social Science and Humanities Non-degree Award
Namuguzi Namuguzi Mary
ID:
Exploring Individual Health-Promoting Lifestyle Behaviours for Prevention of Hypertension in Rural Communities of Uganda
REFNo: HS617ES

1. What knowledge do individuals have about prevention of hypertension in rural communities of Uganda?
2. What individual health lifestyle behaviours influence the prevalence of hypertension in rural communities of Uganda?
3. What is the prevalence of hypertension in two rural communities (Mende and Kasengejje) of Uganda?
4. How do individuals in rural communities of Uganda prevent hypertension?
5. What interventions are effective for the prevention of hypertension in Low and Middle-income countries?

 Uganda 2020-10-27 2023-10-27 Medical and Health Sciences Degree Award
Viola  Nyakato Nilah
ID: UNCST-2021-R013698
 Understanding the Marginalized Indigenous Batwa People of South-Western Uganda
REFNo: SS452ES

The general objective of the study is to generate data on the livelihood of Batwa indigenous community living in the districts of Kabale, Kisoro, Rubanda and Kanungu in Southwestern Uganda, in order to build evidence around the factors that compromise their livelihoods across policy, access to services and resources, culture and their history/heritage.

The specific objectives of the study will be:
1.To assess and understand the vulnerable issues and factors of marginalization of the Batwa from the districts of Kabale, Kisoro, Rubanda and Kanungu
2.To generate evidence on the social, structural and other barriers the Batwa Community face for their livelihood improvement interventions
3.To undertake participatory approaches to develop and evaluate development interventions improvement for the Batwa livelihoods
4.To propose recommendations on how to develop appropriate livelihood improvement programmes and policies for Batwa indigenous people communities living South Western Uganda.

 Uganda 2020-10-27 2023-10-27 Social Science and Humanities Non-degree Award
LYNDA NAKALAWA ESTHER
ID:
The dilemma of youth empowerment in Uganda:interrogating the mindset question
REFNo: SS454ES

Research Questions
Overall Research Question: How have the mindsets of youth from selected youth empowerment programs in Uganda been shaped by the social, cultural and historical processes at play in the society within which these programs operate.
Specific research questions
1. How are youth positioned in the social, cultural and historical discourse around youth empowerment in Uganda?
2. What is the impact of this discourse on the mentalities, including attitudes, unconscious biases or ingrained beliefs of youth in selected youth empowerment programs in Uganda?
3. How are the youth’s mindsets expressed in their behavior or actions?
 Uganda 2020-10-27 2023-10-27 Social Science and Humanities Degree Award
Rodgers Tugume
ID:
prevalence and factors associated with pelvic organ prolapse among women attending gynaecological outpatient clinic of Mbarara Regional Referral Hospital
REFNo: HS706ES

1.To determine the prevalence of pelvic organ prolapse among women attending gynaecological outpatient clinic at Mbarara regional referral hospital.
2.To determine the commonest stage of pelvic organ prolapse at presentation of women attending gynecological outpatient clinic at MRRH.
3.To identify the socio-demographic, obstetric, gynaecological, and medical factors associated with pelvic organ prolapse among women attending gynecological clinic at Mbarara Regional Referral Hospital.

 Uganda 2020-10-27 2023-10-27 Medical and Health Sciences Degree Award
George  Semivule William
ID:
MANAGEMENT PRACTICES AND IMPLEMENTATION OF STRATEGIC PLANS, IN NDEJJE UNIVERSITY UGANDA
REFNo: SS480ES

1. To determine the effect of planning implementation of of strategic plans on Ndejje University.

2. To assess the effects of organizing on implementation of the strategic plans of Ndejje University.

3. To establish how leading affects the implementation of strategic plans of Ndejje University.

4. To determine the effect of controlling on implementation of the strategic plans of Ndejje University.
Uganda 2020-10-27 2023-10-27 Social Science and Humanities Degree Award
Felix Twinomucunguzi Rutaro Baineki
ID:
A Socio-Technical Decision Support Framework for Reducing Groundwater Contamination Risk in Peri-Urban Areas, Kampala
REFNo: SS482ES

Determine the recent extent of groundwater contamination in low income peri-urban areas, with focus on emerging organic contaminants.

Investigate the specific vulnerability to emerging groundwater contamination in low income peri-urban areas.

Assess the key socio-institutional factors influencing increased risk of groundwater contamination in low income peri-urban areas.

Develop qualitative decision support framework for reducing risk of groundwater contamination in low income peri-urban areas.

 Uganda 2020-10-27 2023-10-27 Social Science and Humanities Degree Award
Hakim Sendagire
ID:
Evaluation of the World Health Organization criteria and the Uganda National Policy; antiretroviral treatment regimen switch, from first line to second line HIV drug combinations, following ‘virological failure but without drug resistance testing’.
REFNo: HS743ES

1. To determine the prevalence of virologic failure among patients receiving first line failure in Uganda.
2. Establish the resistance patterns at the time of switching therapy.
3. Validate the correctness of the decision to switch therapy, thereby evaluate the WHO public health approach in management of ART.

Uganda 2020-10-27 2023-10-27 Medical and Health Sciences Non-degree Award
Jackson Orem
ID: UNCST-2021-R012016
 Effect of Patient Navigation Services on Patients’ Experience of Cancer Care and Adherence to Treatment at Uganda Cancer Institute 2020-2023
REFNo: HS950ES

Overall research Objective
To assess the effect of patient navigation program on patients’ experience of cancer care and adherence to treatment at Uganda Cancer Institute
Specific research Objectives
1.To assess changes in patient barriers to accessing care and adhering to treatment as a result of the implementation of patient navigation services at UCI
2.To assess the changes in patients’ experience of cancer care as a result of the implementation of patient navigation services at UCI
3.To assess the changes in adherence to treatment as a result of the implementation of patient navigation services at UCI.

 Uganda 2020-10-27 2023-10-27 Medical and Health Sciences Non-degree Award
Patrick  Ogwok
ID:
Effectiveness of a combined food literacy and physical activity intervention to optimize metabolic health among women of reproductive age in urban Uganda
REFNo: HS974ES

1. To assess the effect of the combined food literacy and physical activity intervention on metabolic health (waist circumference, blood glucose; blood lipid profile – total cholesterol, HDL cholesterol and triglycerides; body composition and blood pressure) of WRA in urban Uganda 2. To assess the effect of the combined food literacy and physical activity intervention on moderate physical activity behavior among WRA in urban Uganda 3. To assess the effect of the combined food literacy and physical activity intervention on consumption of fruits and vegetables among WRA in urban Uganda 4. To assess the effect of the combined food literacy and physical activity intervention on the use of food, nutrition and physical activity information among WRA in urban Uganda
Uganda 2020-10-27 2023-10-27 Medical and Health Sciences Degree Award
Gloria Seruwagi Seruwagi
ID:
Adherence, Lived Experiences and Resilient Transformation among “slumdwellers” (ALERTs) in COVID-19: A study of Ki-Mombasa and Kabalagala-Kataba slums in Kampala
REFNo: SS555ES

General objective
We seek to study slum dwellers’ lived experiences, assess behavioural shifts and determine public compliance and social behaviour in light of COVID-19.
Specific objectives
1. To assess knowledge or awareness of COVID-19 and local perception of risk in urban slums. This will also capture infodemic issues, myths, fears, etc
2. To identify local pre-post COVID attitudes and practices relating to health and social norms. This will include e.g. WASH, healthseeking behaviour, community cohesion practices
3. To explore implementers’ interpretation and enforcement of COVID-19 guidelines. Implementers will include healthworkers, police, LDUs, politicians, etc
4. To determine the feasibility of, and adherence to, COVID-19 preventive measures.
Will include local interpretations, experiences, innovations, improvisations and explanatory factors
5. To identify community resources, systems and assess their efficacy in the COVID-19 response. This will cover essential systems & services including health, social care and community leadership


 Uganda 2020-10-26 2023-10-26 Social Science and Humanities Non-degree Award
Michael Olanya West
ID:
Head Teachers’ Views of their Instructional Leadership Practices; A Case Study of Four Primary School Head Teachers in Kitgum Municipal Council, Uganda
REFNo: SS568ES

a) To investigate how primary school head teachers in Kitgum Municipal Council perceive their instructional leadership practices
b) To find out head teachers’ understanding about instructional leadership practices
c) To find out factors which facilitate or hinder head teachers’ practice of instructional leadership
 Uganda 2020-10-26 2023-10-26 Social Science and Humanities Degree Award
JOAN KEMPANGO
ID:
“Assessment of Factors Associated with Acquisition of Clinical Competences Among Undergraduate Nursing Students in Ugandan Universities”
REFNo: HS639ES

1) To determine the involvement of clinical mentors in the undergraduate acquisition of clinical skills;
2) To investigate clinical mentors preparedness in facilitating undergraduate student’s clinical skills
3) To assess student perception of the learning environment in a clinical set-up among undergraduate nursing students in Uganda;
4) To identify the available learning resources for the acquisition of clinical skills among undergraduate nursing students in Uganda;
5) To establish the influence of institutional factors on competence acquisition by the undergraduate nurses in Uganda.
6) To establish the effect of student factors on clinical competence acquisition by the undergraduate nurses in Uganda.

 Uganda 2020-10-22 2023-10-22 Medical and Health Sciences Degree Award
Mary  Nanteza Bridget
ID:
Does recombination of polio viruses with locally circulating enteroviruses play a role in acute flaccid paralysis and vaccine-derived polioviruses?
REFNo: HS770ES

1. General Objective
To identify polio mutations that are common to AFP, and cVDPV cases.

2. Specific Objective
i) To determine if polio/non-polio recombination has occurred in AFP cases
ii) To characterize primary recombination events in the polio virus genome that are associated with AFP, and
iii) To compare the recombination events common in AFP with published cVDPVs and characterize the events that could be common in VDPVs.

 Uganda 2020-10-22 2023-10-22 Medical and Health Sciences Non-degree Award
Munshi Sulaiman
ID:
Evaluation of the Disability-Inclusive Ultra-Poor Graduation Programme (DIG) in Uganda
REFNo: SS529ES

1. To estimate the impact of the Ultra-Poor Graduation programme on poverty, livelihood and social participation of people with disabilities and their families, compared to controls who do not receive the intervention.
2. To estimate the impact of the Ultra-Poor Graduation programme on poverty, livelihood and social participation of people with disabilities and their families, compared to people without disabilities who received the intervention
Bangladesh 2020-10-22 2023-10-22 Social Science and Humanities Non-degree Award
Cristina Clerici
ID:
The Parallel Pandemic of Domestic Violence Against Women in Uganda: is the Lockdown to Blame?
REFNo: SS553ES

Our project seeks to study the relationship between IPV and the relative economic conditions of spouses in Uganda, by exploiting the implementation of COVID-19 containment measures as a source of exogenous variation in the woman's relative income.
Italy 2020-10-22 2023-10-22 Social Science and Humanities Degree Award
Pontiano  Kaleebu
ID: UNCST-2020-R019901
 PERCEPTIONS OF HEALTHCARE WORKERS REGARDING LOCAL INFECTION PREVENTION AND CONTROL PROCEDURES FOR COVID-19
REFNo: HS867ES

Primary aim: To better understand health care worker perceptions of infection prevention and control procedures to prevent Covid-19 transmission.

Objectives:
1. To evaluate healthcare worker perceptions of their preparedness to ensure effective infection prevention and control of Covid-19 in healthcare settings, and to evaluate healthcare worker’s level of trust in their healthcare organization/facility.

2. To consider how these factors vary
a. Across age, staff role, and length of clinical experience;
b. Between respondents whose hospital is receiving suspected/ confirmed patients and those whose hospitals are not;
c. Between those who have direct experience of treating Covid-19 patients and those who have not.
d. Across different regions in the country that have dealt with other epidemics other than COVID19.
e. Between countries in different global regions where this survey is conducted.

 Uganda 2020-10-22 2023-10-22 Medical and Health Sciences Non-degree Award
Imran Rasul
ID:
Firm Dynamics and Worker Resilience to the COVID-19 Shock in Uganda
REFNo: SS565ES

The overall objective of this prpject is to study the effects of the Covid-19 shock on SMEs and workers in Uganda. The study will aim at answering the following research questions:
1. What firm-level characteristics predict firm survival and growth in an expansionary business cycle? Do the same characteristics predict firm resilience to the shock of COVID-19?
2. How do markets evolve during periods of economic growth, in terms of the number of firms, firm size distribution, and level of competition? How does the COVID shock affect the structure and level of competition within markets?
3. How do different types of skills training affect workers’ resilience to the economic shock caused by COVID-19?

 UK 2020-10-22 2023-10-22 Social Science and Humanities Non-degree Award
Fred Wabwire-Mangen
ID: UNCST-2021-R013549
 Assessing the Burden of Asymptomatic SARS-COV-2 Infection among Patients Seeking Health Care at Health care facilities in Uganda
REFNo: HS889ES

To determine the prevalence of SARS-CoV-2 among a sample of patients seeking health care and HCWs at participating surveillance sites who do not meet the case definition for COVID-19.
 Uganda 2020-10-22 2023-10-22 Medical and Health Sciences Non-degree Award
ANNETTEE NAKIMULI OLIVIA
ID: UNCST-2022-R011194
 In-depth case study of large referral maternity wards in four countries in sub-Saharan Africa: a case study of Kawempe National Referral Hospital and Mulago Specialized Women and Neonatal Hospital in Uganda
REFNo: HS907ES

1) To document the preparedness and response to COVID-19 among large maternity/newborn wards in four countries in sub-Saharan Africa over time
2) To serve as a platform for exchange of information and experiences across the contexts studied.

 Uganda 2020-10-22 2023-10-22 Medical and Health Sciences Non-degree Award
Joyce Kambugu Balagadde
ID: UNCST-2020-R014996
 A regional approach to improved childhood cancer drug access in East Africa: Understanding access and coordinating procurement
REFNo: HS681ES

1. Undertake detailed institutional and health system data collection to obtain key metrics of drug availability and price in participating jurisdictions 2. Describe policies and practices related to childhood cancer drug procurement and provision in partner jurisdictions 3. Analyse the key determinants of childhood cancer drug access in the health system context 4. In partnership with national governments, establish agreements and mechanisms for coordinated procurement of essential childhood cancer medicines, based on evidence-based estimates of need.
Uganda 2020-10-21 2023-10-21 Medical and Health Sciences Non-degree Award
Brian Kanaahe Mwebaze
ID:
“Understanding And Addressing The Sexual Reproductive Health And Rights Needs Of Young Women And Girls In Humanitarian Settings In Nigeria And Uganda"
REFNo: SS611ES

1.Synthesize existing literature on the Sexual Reproductive Health and Rights challenges of young refugee women and girls, highlighting promising solutions and best practice service delivery models.
2.Conduct participatory, mixed methods formative research to generate evidence on the Sexual Reproductive Health and Rights knowledge and challenges of young women and girls in the target refugee settings.
3.Assess existing service provision models against global standards and best practice guidelines for adolescent/youth friendly Sexual Reproductive Health and Rights services in humanitarian settings with a comparison between refugees and Internally Displaced Persons (IDPs).
4.Support existing Sexual Reproductive Health and Rights initiatives in refugee camps in the target countries to use emerging evidence to improve advocacy for, demand for, and provision of Sexual Reproductive Health and Rights services for adolescent girls.
 Uganda 2020-10-21 2023-10-21 Social Science and Humanities Non-degree Award
Harriet Mpairwe
ID: UNCST-2025-R017439
 Psychosocial well-being and urbanisation among adults in Uganda: A pilot study
REFNo: HS831ES

1. To assess the feasibility of collecting data on psychosocial factors among adults in urban (Kampala) and rural (Mpigi and Wakiso) Uganda
2. To establish the hair cortisol concentration assay in our immunology laboratory
3. To assess the acceptability of scalp hair sample collection for research purposes

 Uganda 2020-10-19 2023-10-19 Medical and Health Sciences Non-degree Award
Fred Ssewamala
ID: UNCST-2020-R014060
 Suubi4STEM: A signature program to advance STEM education in Africa
REFNo: SS475ES

Objective 1. Test the feasibility, acceptability, and preliminary impact of innovative Suubi4STEM intervention in promoting educational STEM opportunities and life options for young people in Uganda.

Objective 2. Qualitatively examine participants’ and facilitators’ intervention experiences and identify individual, family and institutional-level facilitators and barriers to Suubi4STEM intervention implementation and participation. Objective 3. Evaluate the cost of implementing Suubi4STEM. Objective4. Disseminate program findings to promote the Suubi4STEM intervention on a larger scale

 Uganda 2020-10-16 2023-10-16 Social Science and Humanities Non-degree Award
Mandela Wangoola Robert
ID:
FACTORS INFLUENCING TRYPANOSOMA BRUCEI RHODESIENSE STABILITY IN CATTLE RESERVOIR IN LANGO SUB REGION
REFNo: NS135ES

General Objective
• Evaluate the factors influencing Trypanosoma brucei rhodesiense infections persistence and stability in the cattle reservoir in Lango sub region
Specific objectives
(i) To determine the prevalence of bovine trypanosomiasis in Lango sub region.
(ii) Assess the stability of T. b rhodesiense in naturally infected cattle in Lango sub region
(iii) Evaluate risk factors leading to continued cattle trypanosomiasis infection in Lango sub region

 Uganda 2020-10-16 2023-10-16 Natural Sciences Degree Award
Sara Nsibirwa
ID: UNCST-2021-R012889
 Antimicrobial resistance in trauma and burn patients with blood stream or wound infections – an observational cohort study from Kampala, Uganda
REFNo: HS815ES

The primary aims:
• To determine the prevalence of blood stream due to specific bacterial and fungal pathogens resistant to first choice empirical treatment in trauma and burn patients.
• To determine the prevalence of wound infections due to bacterial and fungal pathogens resistant to first choice empirical treatment in trauma and burn patients
The secondary aims:
• To describe the proportion of burns and trauma patients requiring a switch of antibiotic or antifungal treatment following wound swab and blood culture results.
• To describe the clinical outcomes of trauma and burn patients with blood stream and wound infections due to bacterial and fungal pathogens resistant to first choice empirical treatment
• To identify risk factors for the development of wound and blood stream infections due to resistant bacterial and fungal pathogens among trauma and burn patients.


Uganda 2020-10-15 2023-10-15 Medical and Health Sciences Non-degree Award
Emmanuel Gusango Humphrey
ID:
Constructivist informed teaching and preparation of students in Primary Teachers Colleges of South Eastern Region in Uganda
REFNo: SS498ES

i. Explore the constructivist principles used in the instruction of students in Primary Teachers Colleges.
ii. Examine the constructivist practices applied to the school practice supervisory process in Primary Teachers Colleges.
iii. Examine the implementation of coaching in the preparation of students’ professional growth.

Uganda 2020-10-14 2023-10-14 Social Science and Humanities Degree Award
Robert Tweyongyere
ID:
Optimizing SMART Dairy Technologies for Efficient Sustainable Productivity of Dairy Farmers in Uganda
REFNo: A80ES

Specific objectives
1. Determine the dairying problems and constraints, current solution options and priority list of solutions which are gender sensitive across age and space.
2. Determine the dairy farmers’ cattle feeding and breeding practices in the milk sheds of Uganda
3. Determine local feed ingredients nutrient profile for optimal dairy feed ration formulation
4. Develop a farmers’ community based breeding program
5. Increase Farmers’ access to elite genetics by artificial breeding technologies (artificial insemination(AI) and Embryo transfer(ET))
6. Determine the nutritional-metabolic profiles among the dairy cattle in selected DaFaN clusters to Optimize cost-effective forage production, preservation and utilization
7. Determine animal health and breeding profile parameters generated by ruminal or collar sensor technology for effective monitoring of individual animals on farms in Uganda

 Uganda 2020-10-14 2023-10-14 Agricultural Sciences Non-degree Award
Robert Newton Edward
ID: UNCST-2023-R006537
 Community surveillance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and of coronavirus disease-2019 (COVID-19) in high risk and general populations.
REFNo: HS823ES

1. To measure the changing incidence and prevalence of SARS-CoV-2 over time and, associated mortality. 2. To assess the impact of co-morbidities on acquisition and survival of SARS-CoV-2. 3. To examine in greater depth the public understanding of COVID-19 and the experience of the surveillance exercise.
UK 2020-10-14 2023-10-14 Medical and Health Sciences Non-degree Award
Robert Tweyongyere
ID:
EFFECTIVENESS OF ANTHELMINTICS IN CATTLE AND GOATS IN MIXED FARMING COMMUNITIES IN MBARARA, KIRUHURA SEMBABULE AND NAKASONGOLA DISTRICTS
REFNo: A83ES

General Objective:
To assess effectiveness of dewormers and generate information that would support decision on improving management of anthelmintics in Uganda

Specific objectives:
1. To document the knowledge, attitude and deworming practices of selected livestock farmers in Mbarara, Kiruhura, Sembabule and Nakasongola districts
2. Determine the worm burden among cattle and goats on the selected farms
3. To determine the ‘clinical efficacy’ of five identified dewormers commonly available to the farmers

Uganda 2020-10-14 2023-10-14 Agricultural Sciences Non-degree Award
Simon Peter Kibira Peter Sebina
ID: UNCST-2019-R000492
 Improving quarantine in Uganda as a key measure to combat COVID-19: Compliance, experiences, gaps and opportunities
REFNo: HS832ES

1. To determine compliance with COVID-19 quarantine measures among self and institutional quarantined persons in Uganda.

2. To determine factors associated with compliance with COVID-19 quarantine measures among self and institutional quarantined persons in Uganda.

3. To explore experiences and coping mechanisms among self and institutional quarantined persons in Uganda.

4. To identify gaps in the management and opportunities for improvement of the quarantine process in Uganda.
 

 Uganda 2020-10-14 2023-10-14 Medical and Health Sciences Non-degree Award
Victoria Nankabirwa
ID: UNCST-2021-R011871
 A multicenter, phase III, double-blind, randomised, active-controlled study to evaluate the efficacy and safety of VPM1002 in comparison to BCG in prevention of Mycobacterium tuberculosis infection in newborn infants
REFNo: HS838ES

Primary objectives
1. To demonstrate that VPM1002 is non-inferior to BCG SII in providing protection against incident Mtb infection
2. To demonstrate that vaccination with VPM1002 is superior to BCG SII in providing protection against incident Mtb infection

Secondary objectives
1. To compare the safety and tolerability profile of VPM1002 and BCG SII administered as a single dose to newborn infants
2. To compare the protective efficacy of VPM1002 versus BCG SII against TB disease
3. To compare the protective efficacy of VPM1002 versus BCG SII against sustained Mtb infection

Exploratory objectives
1. To evaluate the immunological response to vaccination with a single dose of VPM1002 compared to BCG SII in a subset (immunogenicity cohort) of HIV-exposed and HIV-unexposed newborn infants in terms of the following parameters:
o Concentration of Interferon (IFN)-γ in the supernatant after antigen re-stimulation as determined by ELISA
o CD4+ and CD8+ T-cells after antigen stimulation as determined by Fluorescence-activated cell staining/Intracellular cytokine staining (FACS/ICS)
o Transcriptomics
o Antibody production
2. To evaluate occurrence of QuantiFERON® Gold Plus In-tube test (QFT) conversion, where conversion is defined using alternative QFT thresholds (e.g. > 4 IU/ml); and sustained QFT conversion, where sustained conversion is defined as QFT ≥ 4IU /ml maintained for approximately 6 months following initial QFT conversion, compared across trial arms in all participants.
3. To determine the mortality rate in children receiving VPM1002 compared to BCG SII

Uganda 2020-10-14 2023-10-14 Medical and Health Sciences Non-degree Award
Victoria Nankabirwa
ID: UNCST-2021-R011871
 SARS-CoV-2 infection and COVID-19 in women and their infants in Kampala, Uganda
REFNo: HS915ES

Overall aim
To describe how the COVID-19 epidemic and Uganda's countermeasures affect women and their newborns, especially newborns of HIV-1 positive mothers, and to test whether BCG vaccination offers protection against SARS-CoV-2 infection and COVID-19.

Specific objectives
1. To investigate if BCG vaccination of HIV-1 exposed infants at birth or at 14 weeks of age protects them against SARS-CoV-2 infection and COVID-19 until 14 weeks of age or against COVID-19 between 15 and 52 weeks of age, respectively.
2. To estimate the evolving prevalence of SARS-CoV-2 infection and of COVID-19 among HIV-1 positive as well as among HIV-1 negative women who have recently given birth, and describe their association with hospitalization on the day of birth, complications during delivery, low birth weight, and other adverse outcomes
3. To estimate the evolving 14-week cumulative incidence of SARS-CoV-2 infection and of COVID-19 among mothers and babies, and evaluate whether maternal HIV-1 infection affects maternal and infant risk of developing COVID-19 of varying severity
4. To evaluate the impact of wide-ranging preventive measures to control COVID-19 on women giving birth during the epidemic, their children, and their families

 Uganda 2020-10-14 2023-10-14 Medical and Health Sciences Non-degree Award
Emanuel  Peter L
ID:
Development of Standardized Herbal Formulation: Synergy between Momordica charantia, Aloe vera and Abelmoschus esculentus for Glycemic Control
REFNo: NS119ES

Objectives
1. To establish ethnomedical use of M. charantia and A. esculentus among indigenous community in Tanzania.
2.To establish physicochemical and stability parameters of freeze dried aqueous extracts of the three plant species separately in pre-formulation studies.
3. To evaluate efficacy of combined freeze dried extracts in different ratios of doses of M. charantia, A. esculentus and A. vera in vivo.
4. To establish safety profile of best optimal dose combination of M. charantia, A. esculentus and A. vera on healthy Wistar female rats.
5. To design a solid pharmaceutical dosage form of the optimal dose combination and evaluate its stability, safety and efficacy in vivo.

Tanzania 2020-10-12 2023-10-12 Natural Sciences Degree Award
Christine Aanyu
ID:
EQUITABLE MATERNAL CARE FOR WOMEN WITH DISABILITY (EMeralD) STUDY
REFNo: HS722ES

1) Specific Aim 1. Conduct an analysis of disability, pregnancy and birth outcomes, and maternal health care utilization data for pregnant women with disabilities in Uganda.
2) Specific Aim 2. Understand the needs and perceptions of pregnant women with disabilities and identify availability of, and barriers to accessing, maternal health care services.
3) Specific Aim 3. Formulate and develop a model for disability-friendly services for pregnant women.

Uganda 2020-10-07 2023-10-07 Medical and Health Sciences Non-degree Award
David Serwadda -
ID:
Characterizing community exposure to SARS-CoV-2 in Uganda, and assessing biological determinants of virus spread
REFNo: HS878ES

1.Assess the diagnostic sensitivity and specificity of the CoronaChekTM rapid COVID-19 IgM/IgG lateral flow test (CoronaChekTM by Hangzhou Biotest Biotech Co Ltd) for anti- SARS-CoV-2 antibodies detection in Uganda.
2.Conduct enhanced surveillance of COVID19-like symptoms in the context of an existing population cohort and assess the predictive value of prevailing symptoms for COVID-19 exposure based on rapid serological testing in this region.
3.Determine rates of sero-reactivity/positivity among key health care workers at high-volume health centers III and IV and also among PCR-negative contacts of confirmed COVID-19 cases in the region.
4.Explore ‘prior importation of COVID-19 infection in Uganda”/ pre-existing sero-reactivity (may due to ‘related’ coronavirus strains/shared epitopes) in purposively selected archived sera, prioritizing from truck drivers and commercial sex workers that was collected before the lockdown in Uganda / Rakai region.

Uganda 2020-10-06 2023-10-06 Medical and Health Sciences Non-degree Award
Richard Idro
ID: UNCST-2021-R013599
 Dihydroartemisinin-Piperaquine or Sulphadoxine-Pyrimethamine for the Chemoprevention of Malaria in Children with Sickle Cell Anaemia in eastern and southern Africa: a double blind randomised trial (the CHEMCHA trial)
REFNo: HS709ES

Primary objective
The general objective is to determine the efficacy and safety of malaria chemoprevention with weekly single day courses of DP compared to monthly single courses of SP in children with SCA in eastern and southern Africa.

Secondary objectives
1. Assess the feasibility and stakeholder perceptions on the uptake (acceptability) and the potential for future roll-out of weekly DP vs monthly SP.
2. Determine the safety of cumulative dosing of DP, especially on cardiac function.
3. Monitor the development of malaria parasite resistance to DP in clinical isolates over time.
Assess patients’ health-related quality of life, cost-effectiveness, equity and economic implications of using weekly courses of DP vs monthly courses of SP as chemoprevention in SCA.
5. Assess acceptability of weekly courses of DP for malaria chemoprevention in SCA vs monthly courses of SP as chemoprevention in SCA.
6. Conduct policy advocacy to engage key stakeholders on policy decisions on using weekly courses of DP or monthly courses of SP for the chemoprevention of malaria in SCA.
 Uganda 2020-10-02 2023-10-02 Medical and Health Sciences Non-degree Award
Richard Idro
ID: UNCST-2021-R013599
 Hydroxyurea therapy for Neurological and Cognitive Protection in Pediatric Sickle Cell Anemia in Uganda: A single arm open label trial, “BRAIN SAFE II”
REFNo: HS846ES

The primary objective is to determine the impact of daily oral hydroxyurea therapy, 20- 30mg/kg/day, on the frequency and severity of Sickle Cell Vasculopathy(SCV) in a cohort of children treated for three years, as measured by 3 distinct outcomes: abnormal TCD, neurocognitive impairment and primary stroke, compared with baseline.

Secondary objectives
1.Evaluate the impact of Hydroxyurea therapy on structural SCV using MRI and MRA in a randomly selected subset of this cohort.
2.Assess changes to anemia, CRP and malnutrition status during hydroxyurea therapy, over time, compared with baseline levels.


 Uganda 2020-10-02 2023-10-02 Medical and Health Sciences Non-degree Award
Sarah Kiguli
ID: UNCST-2021-R013020
 Nutritional Treatment in Pneumonia Trial. (NuTiP)
REFNo: HS911ES

To establish whether supplementary feeding for 56-days (8 weeks) using Ready to Use Therapeutic Feeds (RUTAFA) in children between 6 months and 12 years with respiratory distress complicated by hypoxia versus usual standard care will improve outcome at 90-days.
 Uganda 2020-10-02 2023-10-02 Medical and Health Sciences Non-degree Award
mariam Namutebi
ID:
TEENAGE FIRST TIME MOTHERS’ PERCEPTIONS ABOUT THEIR HEALTH CARE NEEDS AND THE GAPS IN POSTPARTUM CARE.
REFNo: HS780ES

General objective:
To explore the teenage first time mothers’ perceptions about their postpartum care needs and the gaps in the facility based postpartum care
Specific Objectives:
1. To explore the teenage first time mothers’ perceptions about their postpartum care needs.
2. To identify the current gaps in the facility based postpartum care provided to teenage first time mothers.

 Uganda 2020-10-01 2023-10-01 Medical and Health Sciences Non-degree Award
Joseph Kagaayi
ID: UNCST-2024-R015946
 Impact of COVID-19 Lockdown on HIV and Reproductive, Maternal, Neonatal and Child Health services in Masaka region, Uganda
REFNo: HS865ES

1 Goal
The overall goal of the study is to assess the effect of the COVID-19 lockdown on demand and utilization of RMNCH and HIV services and assess coping mechanisms in order to make evidence-based recommendations for mitigation of the impact during the COVID-19 epidemic and future health emergencies and disasters.

Specific aims
1) To determine the effect of COVID-19 lockdown on discontinuation of Antiretroviral therapy (ART) among patients receiving antiretroviral drugs in 12 districts of the Masaka region.
2) To determine the effect of COVID-19 lockdown on Antenatal care (ANC) attendance, facility deliveries, contraception, immunization, EID, HIV testing among all pregnant women and initiation of option B+ among HIV-positive ANC attendees.
3) To determine the effect of the COVID-19 response on viral load monitoring, intensive adherence counseling and HIV viral suppression among clients in the Masaka region,.
4)To explore clients’, district, and health facility knowledge, attitude and experiences (KAE) and coping mechanisms for sustained ART, and RMNCH services. Qualitative exploration of KAE will provide useful pathways for the effect of lockdown measures on demand and utilization of services.

Uganda 2020-10-01 2023-10-01 Medical and Health Sciences Non-degree Award
Cissy  Kityo
ID: UNCST-2021-R013663
 Validation of SARS-CoV-2 detection by Rapid AirJump RNA Amplification (RARA) COVID Test method
REFNo: HS888ES

We will carry out validation of RARA assay in the laboratory before the field evaluation in testing of SARS-CoV-2.
We intend to understand the inherent characteristics of this assay with regard to accuracy (diagnostic sensitivity, diagnostic specificity), Precision (reproducibility), Limit of detection (LOD), Predictive value (negative and positive), and Assay Efficiency.
Uganda 2020-10-01 2023-10-01 Medical and Health Sciences Non-degree Award
KarenBeth Bohan Heikkinen
ID:
Assessment of Online Modules to Increase Knowledge of Geriatric Care in Health Care Professionals RefNo: MAKSHSREC-2020-6
REFNo: HS727ES

To determine the pharmacists’ satisfaction with pharmacy geriatric online training.,To determine the learning preference in terms of online compared to live educational sessions before and after using the online modules for professional development,To determine the retention of knowledge of geriatric care at three months after completion of all five online educational modules.,To assess the improvement of pharmacy professionals’ knowledge of geriatric care after participating in online educational modules.,
 USA 2020-09-29 2023-09-29 Medical and Health Sciences Non-degree Award
Ignatius Odongo Odongo
ID:
Youth Entrepreneurship in South Africa and Uganda: An Investigation of the Influence of Mental Triggers
REFNo: SS487ES

To contribute to the existing discourse on youth entrepreneurship, by introducing a new applied framework from which youth entrepreneurship can be developed based on the influences of mental triggers. The new framework will include, inter alia, a description of the following:
• the environment that can potentially stimulate youth entrepreneurship;
• the kind of entrepreneurship education that will stimulate and provide requisite skills for the nascent youth entrepreneur; and
• the personal characteristics that can be nurtured for entrepreneurial success.
Armed with this new framework, the stakeholders that areresponsible for youth development, particularly in developing countries, will be able to deal with the psychological and other barriers that impede the youth from venturing and succeeding in entrepreneurship.

 Uganda 2020-09-29 2023-09-29 Social Science and Humanities Degree Award
Victoria Nankabirwa
ID: UNCST-2021-R011871
 Preventing Infant Malnutrition with Early Supplementation (PRIMES)
REFNo: HS825ES

Aim 1. To describe local experiences and beliefs related to breastfeeding, breast milk expression, non-maternal food sources and infant weight and health.

Aim 2. To determine the range of newborn weight changes, the typical age at which a newborn returns to birth weight, and any association of newborn weight change with early dietary intake, clinical and demographic characteristics, and breastfeeding behaviors.

 Uganda 2020-09-29 2023-09-29 Medical and Health Sciences Non-degree Award
Fred Bulamba
ID: UNCST-2019-R000026
 Mapping perioperative care pathways to support surgical treatment in Low-and-Middle Income Countries
REFNo: HS642ES

The aim of this project is to understand the context of perioperative health systems in Uganda, including the main barriers encountered in the delivery of care.

Objectives:
1. Develop a collaborative approach to perioperative care pathway mapping
2. Carry out a rapid appraisal to map 5 pathways (three “Bellwether procedures and two elective procedures) in Uganda.
3. Refine the process and extend to three low- and middle-income countries

 Uganda 2020-09-28 2023-09-28 Medical and Health Sciences Non-degree Award
marie nanyanzi
ID: UNCST-2019-R001553
 Point Of Entry Sauti Za Wananchi (Voices of the citizens)Extension Survey
REFNo: SS468ES

To understand the COVID-19 effects on the citizens’ experience and key services they receive during this era of COVID-19 especially ▪ Establish citizen access to safe water; ▪ Establish citizen access and usage of health services and knowledge, Attitudes and Practices (KAPs); ▪ Find out level of participation/involvement/interaction in development and public activities /institutions; ▪ Find out access and usage of financial services amongst citizens; ▪ Find out how; what and when citizen access different type of information including government and development information. ▪ Establish the knowledge, Attitudes and Practices (KAPs) of citizens on different guidelines, policies; laws and regulations etc
 Uganda 2020-09-28 2023-09-28 Social Science and Humanities Non-degree Award
mariam Namutebi
ID:
POSTPARTUM CARE: FACILITY READINESS, MIDWIVES’ PERSPECTIVES AND THE EFFECT OF USING INDIVIDUALIZED CARE PLANS ON POSTPARTUM OUTCOMES.
REFNo: HS773ES

General Objective

To assess the facility readiness for the provision of Postpartum care, explore the midwives’ perspectives about postpartum care and evaluate the effect of using individualized care plans on the postpartum outcomes in the greater Mpigi region.
Specific objectives
1. To assess the facility readiness to provide postpartum care in selected facilities in the greater Mpigi region.
2. To explore the midwives’ perspectives towards postpartum care in the greater Mpigi region.
3. To evaluate the effect of using individualized care plans in the immediate and early postpartum period on the monitoring assessments, physical examination and health education of postpartum women in the greater Mpigi region.
4. To describe the postpartum women’s perspectives and midwives’ experiences of postpartum care provided using individualized care plans

 Uganda 2020-09-28 2023-09-28 Medical and Health Sciences Degree Award
Esther Buregyeya
ID: UNCST-2020-R014116
 Using the human-centred design model to inform local adaptation of COVID-19 prevention measures among high-risk populations in Malaba and Mutukula points of entry in Uganda
REFNo: HS848ES

1. To determine knowledge and risk-perceptions on COVID-19 measures among high-risk populations in Malaba and Mutukula points of entry.
2. To assess uptake of recommended COVID-19 prevention measures measures among high-risk populations in Malaba and Mutukula points of entry.
3. To explore the facilitators and barriers to uptake of the COVID-19 prevention measures measures among high-risk populations in Malaba and Mutukula points of entry.
4. To design, pilot and evaluate localized behavioural interventions to foster uptake of the COVID-19 prevention measures measures among high-risk populations in Malaba and Mutukula points of entry.
 Uganda 2020-09-28 2023-09-28 Medical and Health Sciences Non-degree Award
Kirsten Beyer M
ID: UNCST-2021-R013472
 Geospatial Analysis of Kampala Cancer Registry Data
REFNo: HS873ES

Objective 1: Identify spatial and spatiotemporal patterns of cancer in Uganda. a) Use geospatial mapping techniques to estimate cancer burdens across geographic space and through time. b) Create visual representations of cancer patterns (maps, graphs). Objective 2: Examine relationships between social and environmental factors and cancer outcomes in Uganda. a) Use statistical analysis techniques to determine associations between environmental factors and cancer outcomes. Objective 3: Pilot the collection of new KCR variables a) For each new case, we will attempt to acquire marital status, education level, occupation, religion, national Identification number (NIN) (new in Uganda), and precise geographic location information. Objective 4: Determine the true spatial extent of KCR data collection potential. a) Identify the number of cases that are discovered and excluded under current practice, as well as the individual’s parish of residence.
USA 2020-09-28 2023-09-28 Medical and Health Sciences Non-degree Award
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