Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Alison Elliott
ID: UNCST-2023-R006524
OBTAINING SINGLE-CELL LEVEL INSIGHTS INTO THE IMMUNOLOGICAL AND METABOLIC PATHWAYS ASSOCIATED WITH VACCINE HYPO-RESPONSIVENESS [REVERSE]
REFNo: HS4782ES

1. To measure the SARS-CoV-2 antibody response at baseline, 3 months after prime vaccination and 1 month after boost vaccination in European and Ugandan adults. 2. To characterise peripheral blood mononuclear cells (PBMCs) and their response to prime/booster vaccination with the AstraZeneca ChadOx1 nCoV-19 vaccine in European and Ugandan adults using single-cell technologies
UK 2024-09-10 10:45:15 2027-09-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Brandon Maser
ID: UNCST-2024-R005142
Understanding How Policies, Politics, and National Contexts Influence Access to Opioid Medicines in Uganda
REFNo: HS4768ES

1) To elucidate the policy mechanisms that are used by policymakers to govern access to and safe use of opioid medicines in Uganda. 2) To understand how political factors and national context influence the political priority for improving access to opioid medicines within Uganda’s national government’s policy agenda. 3) To understand how political factors and national context influence how governmental, non-governmental, and transnational actors formulate alternative policy options for ensuring access to opioid medicines in Uganda. 4) To understand how policies governing opioid analgesics and those governing OAT have been uniquely influenced by political factors and national contexts during Uganda’s opioid policy reforms.
Canada 2024-09-10 10:26:35 2027-09-10 Medical and Health Sciences Non-Clinical Trial Degree Award
Francis Busiku
ID: UNCST-2024-R004040
Validity, Feasibility and Acceptability of digital x-ray Computer Aided Diagnosis for Tuberculosis by Village Health Teams in Bududa District- a cross-sectional study
REFNo: HS4792ES

3. To determine the feasibility and acceptability of portable Digital Chest X-ray CAD4TB version 7 by VHTs in Bududa District.,2. To determine the validity of portable Digital Chest X-ray CAD4TB version 7, compared to ZN in Bududa District.,1. To determine the validity of portable Digital Chest X-ray CAD4TB version 7, compared to X-pert MTB/RIF (x-pert) in Bududa District.,To evaluate the diagnostic accuracy of portable CXR CAD4TB as Community TB diagnostic tool in Bududa District in Uganda.,
Uganda 2024-09-10 10:17:27 2027-09-10 Medical and Health Sciences Non-Clinical Trial Degree Award
Achilles Katamba
ID: UNCST-2019-R000540
Peer-led Implementation of TB-HIV Education and Adherence Counselling in Uganda
REFNo: HS4801ES

To evaluate the implementation fidelity and context of a peer-navigation strategy for TB-EC to improve TB treatment and ART outcomes, To determine the feasibility, acceptability, and appropriateness of a peer-navigation strategy for TB-EC and explore the social-behavioral mechanisms for improving adherence and clinical outcomes. ,To evaluate the implementation of a peer-navigation strategy for TB-EC to improve TB treatment completion and ART retention. , To evaluate the effectiveness and implementation of a novel, peer-led TB education and counseling strategy to improve outcomes among persons with tuberculosis (TB) with and without HIV/AIDS and assess the social-behavioral mechanisms underlying the observed treatment effects. ,
Uganda 2024-09-10 10:03:57 2027-09-10 Medical and Health Sciences Clinical Trial Non-degree Award
Okumu Tendo Ivan
ID:
Assessment and remediation of selected heavy metals contaminants in tannery wastewater from selected tanneries in Jinja city and Wakiso district,Uganda
REFNo: NS795ES

Prepare and characterize biochar using green banana peels and coffee husks ,Evaluate the concentration levels, speciation and toxicity of selected heavy metals( Cr,Cu,NI,Pb and Zn) in tannery wastewater.,To assess the concentration levels and to bioremediate selected heavy metals contaminants in tannery wastewaters from designated tanning industries in Uganda,
Uganda 2024-09-10 10:01:32 2027-09-10 Natural Sciences Non-Clinical Trial Degree Award
Robert MPIIRA
ID: UNCST-2022-R005391
Community Development Intervention Strategies and Poverty Alleviation in Wakiso District
REFNo: SS3067ES

(iv) Explore how interactions among development actors affect poverty alleviation in Wakiso district,(iii) Assess if, and to what extent, multipurpose cooperative societies leverage community development intervention strategies in poverty alleviation in Wakiso District,(ii) Analyse the relationship, if any, between the various development strategies and the selected poverty outcomes (income, food security, household assets, agency),(i) Understand how the communities in Wakiso district perceive poverty and development,To generate, using a systems approach, more contextualized knowledge on the effects of skills acquisition, transfers and financial inclusion supported by non-governmental organisations through cooperatives on household income, assets, food security and agency. ,
Uganda 2024-09-10 10:00:24 2027-09-10 Social Science and Humanities Non-Clinical Trial Degree Award
Riccardo Durini
ID:
Comparison in sociality in snared and non-snared chimpanzees
REFNo: NS861ES

The goal is to analyse social behavioural differences between snared and healthy chimpanzee individuals. The comparison focuses on certain traits related to sociality, such as the number and quality of bonds with other individuals, party formation, grooming partners and others.
Switzerland 2024-09-09 14:54:20 2027-09-09 Natural Sciences Non-Clinical Trial Degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
Evaluation of the performance of HIV rapid diagnostic tests on Oral Fluid and Urine for WHO prequalification assessment.
REFNo: HS4871ES

To describe and assess the operational characteristics and ease of use of HIV RDTs on urine or oral fluids and its suitability for use in countries with limited infrastructure (no/limited electricity, no/limited clean water, and inadequate means of biosafety disposal).,To assess inter-reader variability (for subjectively read assays),To assess analytical performance of HIV RDTs for the detection of antibodies to HIV in oral fluid and urine: ? Sensitivity on seroconversion panels compared to a benchmark assay ? Performance on mixed-titer panels ? Subtype detection ? Lot-to-lot variation ,To determine the sensitivity and specificity of HIV RDTs for the detection of antibodies to HIV in oral fluids and urine as compared to a reference algorithm (two EIAs followed by a line immunoassay) in blood- derived specimen and compare them to predefined acceptance criteria for prequalification,The overall objective is to evaluate and compare the accuracy of HIV rapid tests for the detection of HIV antibodies in oral fluids and urine against established performance criteria. ,
Uganda 2024-09-04 18:43:09 2027-09-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ANTHONY NUWA
ID: UNCST-2022-R011102
Using behavioural insights to design a behavioural intervention to accelerate malaria mosquito net use in Uganda: The Be In A Net study
REFNo: SS3095ES

1. The aim of this study is to understand the behaviours, barriers, and facilitators affecting the use of insecticide-treated nets (ITNs) in selected areas of Uganda in order to develop a behavioural intervention to increase ITN use,To design and refine a behavioural intervention to increase mosquito net use based on behavioural science principles.,To conduct exploratory research to examine the role of psychological, cognitive, emotional, cultural and social factors impacting ITN use to inform the design of a behavioural intervention to encourage mosquito net use.,
Uganda 2024-09-04 18:41:43 2027-09-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
molly naisanga
ID: UNCST-2023-R005602
Mental Health and Psychosocial Support Services for Refugee Children and Adolescents with HIV in West Nile Uganda.
REFNo: HS4486ES

2. To explore experiences with available mental health and psychosocial support services for HIV-positive school going refugee children and adolescents in the West Nile region of Uganda.,1. To explore ongoing and past mental health and psychosocial support services for HIV-positive school going refugee children and adolescents in the West Nile region of Uganda,To explore ongoing and past mental health and psychosocial support services for HIV-positive school going refugee children and adolescents in the West Nile region of Uganda and to explore their experiences with available mental health and psychosocial support services.,
Uganda 2024-09-04 13:33:35 2027-09-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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