Eugene Ruzagira
ID: UNCST-2023-R008282
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A mixed-methods observational study to assess the feasibility of conducting COVID-19 vaccine trials among healthcare workers in Uganda
REFNo: HS807ES
I. To assess willingness to participate in COVID-19 vaccine studies and associated factors among healthcare workers in Uganda
II. To estimate the prevalence of underlying health conditions that are associated with poor COVID-19 outcomes among healthcare workers in Uganda
III. To describe the knowledge, attitudes, and practices regarding infection with SARS-CoV-2 and COVID-19 vaccine research among healthcare workers in Uganda
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Uganda |
2020-08-07 |
2023-08-07 |
Medical and Health Sciences |
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Non-degree Award |
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Mary Ann Etling
ID:
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Ethnographic analysis of children with mobility disabilities and their caregivers in Gulu district of post-conflict northern Uganda
REFNo: HS311ES
Identify ongoing needs of children with mobility disabilities and their caregivers in Gulu district.
Characterize physical, economic, social, and environmental barriers that children with mobility disabilities and their caregivers experience in Gulu district.
Investigate changes in the family and how they impact care for children with mobility disabilities in Gulu district.
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USA |
2020-08-06 |
2023-08-06 |
Medical and Health Sciences |
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Non-degree Award |
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Ronald Moses Galiwango
ID: UNCST-2024-R015239
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SARS CoV-2 Infection, Transmission, and Natural History of COVID-2019 Among Persons With and Without HIV and Tuberculosis
REFNo: HS712ES
Primary objective
• Evaluate the impact of HIV infection on presentation and outcomes of COVID-19 disease
Secondary objectives
• Evaluate household transmission of COVID-19 disease among persons with and without HIV infection
• Evaluate the impact of TB infection on presentation and outcomes of COVID-19 disease
• Among persons living with HIV, evaluate the relationship between routine biomarkers (CD4#, viral load) and outcomes of COVID-19
• Among persons living with HIV, evaluate the impact of being on antiretroviral drugs and different ARV regimens on COVID-19 outcomes
• Understand the impact of nutritional and functional status on persons with COVID-19 infection
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Uganda |
2020-08-06 |
2023-08-06 |
Medical and Health Sciences |
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Non-degree Award |
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Raymond Tweheyo
ID: UNCST-2020-R014507
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Exploring the root causes and cultural norms for healthy timing and spacing of pregnancies and assessing access to quality and voluntary family planning in central and western Uganda.
REFNo: HS787ES
Specific objectives:
1)To explore the socio-cultural norms and sexual reproductive health behaviors that influence the youth’s access to FP information and use of FP services.
2)To assess the health system readiness for provision of family planning and youth friendly services in both public and private facilities.
3)To assess the private pharmacy and drug shop readiness for provision of family planning services.
4)To assess community Village Health Team (VHT) capacity and readiness to offer FP services.
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UK |
2020-08-06 |
2023-08-06 |
Medical and Health Sciences |
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Non-degree Award |
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Bruce Kirenga J
ID: UNCST-2019-R001460
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Assessment of safety and efficacy of COVID-19 Convalescent Plasma for treatment of COVID-19 in adults in Uganda; A randomized controlled trial
(CCP TRIAL)
REFNo: HS816ES
General objective
The overall objective of this project is to assess the safety and efficacy of COVID-19 convalescent plasma in the treatment of COVID-19 in Uganda.
Primary objective
1. To determine the efficacy of COVID-19 Convalescent Plasma, as measured by time to RT-PCR negativity of COVID-19 patients treated with COVID-19 Convalescent Plasma.
Secondary objectives
1. To assess the safety of COVID-19 Convalescent Plasma in the treatment of COVID-19 patients in Uganda
2. To document the time to symptom decrease of patients with positive SARS-CoV-2 RT PCR treated with CCP compared to those on standard of care
3. To assess the ability of CCP therapy to stop progression to severe/critical forms of disease
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Uganda |
2020-08-05 |
2023-08-05 |
Medical and Health Sciences |
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Non-degree Award |
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Jimmy Osuret
ID:
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Effectiveness of safe pedestrian crossings for primary school children in Kampala, Uganda: Implications for road safety management
REFNo: HS659ES
The main objective of this study will be to assess the effectiveness of safe pedestrian crossings in reducing child pedestrian road traffic injuries and death around primary school areas so as to persuade policymakers and practitioners to prioritize child pedestrian road safety.
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Uganda |
2020-08-04 |
2023-08-04 |
Medical and Health Sciences |
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Degree Award |
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Abel Nkolo
ID:
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Multimorbidity, Healthcare Processes, versus Mortality among TB/HIV Patients on ART in Uganda
REFNo: HS692ES
1. Determine the association between multimorbidity (non-communicable disease clusters like diabetes, hypertension malnutrition, cancers etc.) and mortality among TB/HIV patients on ART?
2. Analyze the association between demographic factors (sex, age and marital status) and mortality among TB/HIV patients on ART
3. Analyze the association between the phase of TB treatment (Initiation and continuation) and mortality among TB/HIV patients on ART.
4. Determine the association between time of initiation of ART (before the start of TB treatment and after the start of TB treatment) and mortality among TB/HIV patients on ART.
5. Determine the association between the type of TB (pulmonary bacteriologically confirmed, pulmonary clinically diagnosed and extrapulmonary) and mortality among TB/HIV patients on ART.
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Uganda |
2020-08-04 |
2023-08-04 |
Medical and Health Sciences |
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Degree Award |
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Allen Kabagenyi
ID:
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Using Telehealth Services To Support The Continuity Of Family Planning Information, Access, And Utilisation During The Covid-19 Pandemic In Uganda
REFNo: HS799ES
• To conduct a survey among clients on an existing telehealth platform to identify the information gaps and challenges of accessing family planning during the COVID-19 pandemic lockdown.
• To develop an information package for improving access to family planning services
• To assemble a community advisory board (CAB) to review content of the family planning information package
• To pilot the use a telehealth platform for improving continuity and knowledge of family planning services during the COVID-19 lockdown.
• To assess the perceptions towards long-acting reversible family planning methods during the post COVID-19 lockdown. Using the telehealth platform.
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Uganda |
2020-08-04 |
2023-08-04 |
Medical and Health Sciences |
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Non-degree Award |
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IVAN JJOOGA
ID:
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‘Economic analysis of beef cattle fattening systems in Nakaseke District, Central Uganda’
REFNo: A68ES
(i) Overall objective
-To determine the economic performance of beef cattle fattening systems used in Nakaseke District.
(ii) Specific objectives
(a) To assess the profitability of different beef cattle fattening systems in Nakaseke District.
(b) To identify the major challenges hindering the adoption of better beef cattle fattening systems by fatteners.
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Uganda |
2020-08-03 |
2023-08-03 |
Agricultural Sciences |
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Degree Award |
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Katharine Brockett
ID:
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A study of breast cancer awareness and barriers to accessing breast cancer services amongst adult inpatients and their attendants at Bwindi Community Hospital
REFNo: HS755ES
To find out participants awareness of breast cancer focusing on knowledge of risk factors, signs and symptoms and preventative measures.
To ask about participants perceived barriers and identify other issues that may restrict access to breast cancer related care.
|
UK |
2020-08-03 |
2023-08-03 |
Medical and Health Sciences |
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Non-degree Award |
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Doreen Nakimuli
ID: UNCST-2021-R013668
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Understanding Self Injection of DMPA-SC: Consumer Insight Research
REFNo: HS767ES
To understand where consumers get their health and family planning information from, where and how they access family planning products, what might motivate them to choose DMPA-SC self-injection, what are the barriers to choosing self-injection, what are consumers’ perceptions and attitudes towards self-injection.
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Uganda |
2020-08-03 |
2023-08-03 |
Medical and Health Sciences |
|
Non-degree Award |
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Harriet Mayanja-Kizza
ID: UNCST-2021-R013074
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Evaluation of New Diagnostics and Field evaluation of point-of-care triage tests for Active Tuberculosis.
REFNo: HS688ES
The primary objective of the study is:
1. To finalise a POC-MBT TB triage test suitable for global application and to perform field-testing and validation thereof. The target for each validation process will be the World Health Organisation (WHO) target product profile 90% sensitivity and 70% specificity.
Secondary objectives:
1. To compare the efficacy of the POC-MBT’s TB diagnostic ability between certain sub-classification groups, for example by HIV-status, history of previous TB, extra-pulmonary vs pulmonary TB, and positive vs negative smear/GeneXpert® Ultra/culture.
2. To estimate the efficiency of different TB diagnostic algorithms that include the POC-MBT screening test along with clinical and/or radiological and/or sputa results.
3. To evaluate the POC-MBT as an indicator of treatment response during treatment for active TB.
4. To evaluate a prototype 3-marker gene signature on an Xpert mRNA cartridge using fingerstick blood.
5. To store samples and data to allow the testing or validation of future diagnostic candidates and algorithms, such as automated chest X-ray analysis and transcriptomic bio-signatures.
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Uganda |
2020-07-30 |
2023-07-30 |
Medical and Health Sciences |
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Non-degree Award |
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Gloria Seruwagi Seruwagi
ID:
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Knowledge, adherence and the lived experiences of refugees in COVID-19: A comparative assessment of urban and rural refugee settings in Uganda
REFNo: SS511ES
General objective
We seek to study refugee lived experiences, assess behavioural shifts and determine public compliance and social behaviour in both urban and rural refugee settings
Specific objectives
1. To assess knowledge or awareness of COVID-19 and local perception of risk in urban and rural refugee settings. This will also capture infodemic issues, myths, fears, etc
2. To identify local pre-post COVID attitudes and practices relating to health and social norms. This will include e.g. WASH, healthseeking behaviour, community cohesion practices
3. To explore implementers’ interpretation and enforcement of COVID-19 guidelines.
4. To determine the feasibility of, and adherence to, COVID-19 preventive measures.Will include local interpretations, experiences, innovations, improvisations and explanatory factors
5. To identify community resources, systems and assess their efficacy in the COVID-19 response. E.g. this will cover essential systems and services including health, social care and community leadership
6. To compare urban and rural refugees in line with Objectives 1-5
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Uganda |
2020-07-30 |
2023-07-30 |
Social Science and Humanities |
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Non-degree Award |
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David Meya Bisagaya
ID: UNCST-2019-R000837
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Alternative Meningitis therapies Phase II Trial for Cryptococcal Meningitis (AMPLYX-CM)
REFNo: HS583ES
To determine the safety and efficacy for all drugs for the treatment of cryptococcal meningitis Primary: 1) “Early Fungicidal Activity†(EFA), which is the rate of CSF yeast clearance quantified by the change of log10 Cryptococcus CFU/mL CSF/day as measured by serial quantitative CSF fungal cultures over the first ~2 weeks 2) Incidence of Grade 3-5 laboratory Adverse Events 3) Incidence of Grade 3-5 Clinical Adverse Events or SAEs Secondary: 4) 18-week survival time as time to event analysis a. 2 and 10 week survival time will be presented 5) Among 2-week survivors, 18-week hospital-free survival time 6) Tolerability: all cause drug discontinuation, study withdrawal, or lost-to-follow-up 7) 3-month quantitative neurocognitive performance Z-score 8) Pharmacokinetic studies of APX001A concentrations in blood, CSF, and other bodily fluids/tissues; and with respect to concomitant medicines.
|
Uganda |
2020-07-28 |
2023-07-28 |
Medical and Health Sciences |
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Non-degree Award |
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Gertrude Nakigozi
ID:
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Mental Health and Cognition in HIV Infection in Rakai, Uganda
REFNo: HS634ES
Aim 1: Examine separate and interactive effects of HIV and psychosocial determinants on CNS dysfunction in PLWH. Hyp 1. Exposure to sexual/physical trauma or violence will interact with HIV in this population and will be associated with greater impairments/decline in declarative memory, cognitive control, and NVS.
Aim 2: Examine effects of psychosocial determinants on ART adherence in PLWH. Hyp 2. Exposure to sexual/physical trauma or violence will interact with impairments/decline in declarative memory, cognitive control, and NVS will adversely affect ART adherence).
Exploratory Aim 3: Determine biomarkers that relate most strongly and reliably to CNS dysfunction in the context of HIV and/or psychosocial determinants. Hyp 3: Different biomarkers of neuronal damage damage (e.g., neurofilament protein light chain-NFL) and CNS inflammation will relate to patterns of impairment/decline in declarative memory, cognitive control, motor, and NVS in the context of HIV and/or exposure to sexual/physical trauma or violence.
|
Uganda |
2020-07-28 |
2023-07-28 |
Medical and Health Sciences |
|
Non-degree Award |
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WILLIAM MUSAMBA
ID:
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Sub-ethnic Identities and Political Conflict in Uganda: The Case of Busoga (1900 to 1967)
REFNo: SS485ES
1)To analyze the influence of British colonial rule on the ethno-political conflicts in Busoga, 2)To assess the position of the Kyabazingaship (Paramount Chieftaincy) in the ethno-political conflicts in Busoga, 3)To examine the nature of political activism of the civic movements in Busoga namely, Young Busoga Association, the Abataka Association and the Abataka Mwoyo Gwa Busoga (Landlords are the Heart of Busoga), 4)To explore the attitude of post-colonial national leadership towards the ethno-political conflicts in Busoga.
|
Uganda |
2020-07-28 |
2023-07-28 |
Social Science and Humanities |
|
Degree Award |
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Martha Namusobya Sarah
ID:
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Prevalence and factors associated with chronic pulmonary aspergillosis (CPA) among pulmonary tuberculosis (PTB) patients with persisting pulmonary symptoms in Uganda.
REFNo: HS739ES
1. To determine the prevalence of CPA among patients receiving treatment for PTB.
2. To determine factors associated with CPA among patients receiving treatment for PTB.
3. To determine the impact of CPA on health-related quality of life among patients receiving treatment for PTB.
|
Uganda |
2020-07-28 |
2023-07-28 |
Medical and Health Sciences |
|
Non-degree Award |
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George Kwizera
ID:
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HUMAN CAPITAL AND AGRICULTURAL TRANSFORMATION ON RURAL POVERTY REDUCTION IN UGANDA. A CASE OF KISORO DISTRICT
REFNo: SS442ES
1. To establish how education can ensure rural poverty reduction in Kisoro District
2. To explore the effect of training on rural poverty reduction in Kisoro District.
3. To examine how agricultural transformation can ensure rural poverty reduction in Kisoro District
4. To determine the relationship between agricultural transformation and human capital on rural poverty reduction in Kisoro District.
|
Uganda |
2020-07-27 |
2023-07-27 |
Social Science and Humanities |
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Degree Award |
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Tanner Regan
ID:
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Enhancing Voluntary Property Tax Compliance through SMS: A Field Experiment in Kampala, Uganda
REFNo: SS457ES
The overall aim of the research is to identify whether increasing public information on individual’s tax compliance has an effect on tax morale and compliance in the city of Kampala. These findings should help to inform the KCCA in the design of policy changes to increase tax revenues through higher voluntary compliance.
The central question of this research asks, “Does public reporting of tax payments raise compliance?â€. We consider two channels of effect through which public reporting can influence compliance. The first is a direct effect; “How does an individual change their compliance behaviour when they know that this will be publicly reported?†and the second considers the effects of such a policy on tax morale; “How do tax payers change their behaviour when they observe others being publicly reported?â€.
We address other questions to better answer the central question. In order to gain a further understanding of the underlying mechanisms and optimal policy, we will also ask:
• Whether the type of public reporting matters; “How does public reporting affect compliance behaviour when only compliers are reported, or when only non-compliers are reported?â€
• Whether peer group matters for public compliance; “How does public reporting affect compliance behaviour when reporting is done on a village level vs a city level?â€.
• Whether taxpayers are more likely to be influenced by knowledge of compliance of high property worth/’influential’ individuals
We are particular keen to understand how the effects of providing public information on compliance compare with other means of improving voluntary compliance in a context of limited trust in government. These additional methods will be identified based on focus group discussions that will be held between April and May 2020.
|
Canada |
2020-07-27 |
2023-07-27 |
Social Science and Humanities |
|
Non-degree Award |
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Saul Nsubuga Hannington
ID:
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Using a mobile App for contact tracing and monitoring of symptoms for early detection of COVID-19 infection in Uganda
REFNo: HS742ES
1) To develop a mobile App to facilitate early detection of COVID-19 infection in Uganda
2) To determine the acceptability and usability of the App
3) To use the App to document daily symptoms related to COVID-19
4) To use the App to trace and record daily contacts and movements made by people
|
Uganda |
2020-07-27 |
2023-07-27 |
Medical and Health Sciences |
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Non-degree Award |
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