Joseph Lutaakome
ID: UNCST-2020-R008323
|
An International Observational Study to Characterize Adults
Who Are Hospitalized with Influenza or Other Targeted Respiratory Viruses
(INSIGHT Protocol No. 003 version 3.0, dated 27 August 2013); Flu003 PLUS
AND
Genomic Study: INSIGHT Protocol No. 004 version 2.0, dated 27 August 2013 -A substudy of qualifying INSIGHT studies
REFNo: HS1108ES
The objectives of this study for participants with confirmed influenza are to:
1. Characterize individuals who are hospitalized with influenza in terms of demographics, co-morbid conditions, prior influenza vaccination (seasonal, including 2009 H1N1) and pneumococcal vaccination, and use of antivirals, overall and according to influenza type, A or B, and influenza A subtype.
2. Estimate the percent who die and who develop a composite outcome, overall and according to the identified influenza type or subtype: death, a requirement for mechanical ventilation or admission to the intensive care unit (ICU), or prolonged hospitalization following enrollment (duration of hospitalization >28 days) at 60 days after enrollment.
3. Study risk factors, (e.g., patient and viral characteristics, geographic location, influenza type and subtype) for mortality and the composite outcome of death, a requirement for mechanical ventilation or admission to the ICU, or prolonged hospitalization following enrollment (duration of hospitalization >28 days).
4. Establish a repository of oropharyngeal, nasal and lower airway samples to determine a laboratory diagnosis; to molecularly characterize the virus, including subtype, antigenic and genetic analyses; to identify known signature mutations for antiviral drug resistance, mutational evolution, and additional re-assortment; and assess possible co-pathogens.
5. In a subset of patients requiring mechanical ventilation, to collect paired upper and lower airway samples to molecularly characterize the virus according to anatomic location, assess the potential emergence of antiviral resistance and assess possible co-pathogens.
6. Establish a repository of serum and plasma for future studies, including measurement of biomarkers that predict disease severity and measures of host response to infection with influenza virus.
7. Compare the characteristics and outcomes of patients infected with different influenza virus types and subtypes, including 2009 H1N1 virus, over time and by geographic region.
8. Identify and characterize other viral and bacterial pathogens, including coinfections.
The objectives of this study for participants with targeted non-influenza viral respiratory infections are to:
1. At enrollment, characterize individuals who are hospitalized with a targeted viral respiratory disease in terms of possible source of infection and mode of transmission, demographics and co-morbid conditions.
2. At 28 and 60 days of follow-up, estimate the percent who die, require admission to the ICU, have prolonged hospitalization, or recover.
3. Establish a repository of prospectively collected serum, plasma and respiratory tract specimens for future studies, including measurement of biomarkers that predict disease severity and measures of host immune response to infection.
|
Uganda |
2021-02-25 |
2024-02-25 |
Medical and Health Sciences |
|
Non-degree Award |
|
Jane Frances Namatovu
ID: UNCST-2020-R014353
|
CONTINUING PROFESSIONAL DEVELOPMENT FOR PRIMARY CARE DOCTORS IN LOW RESOURCE SETTINGS: DEVELOPING A COMPETENCY-BASED FRAMEWORK
REFNo: HS1170ES
1.To determine the CPD training needs of primary care doctors working in public general hospitals (GHs) and health center IVs (HC IVs) of central Uganda
2.To explore the perceived barriers to and facilitators of CPD among primary care doctors working in public GHs and HC IVs of central Uganda
3.To explore the views of key stakeholders on CPD for doctors working in public GHs and HC IVs of central Uganda
4.To develop a competency-based CPD framework for primary care doctors working in public GHs and HC IVs of central Uganda
|
Uganda |
2021-02-25 |
2024-02-25 |
Medical and Health Sciences |
|
Degree Award |
|
Dennis Muhanguzi
ID: UNCST-2019-R001101
|
Targeting Domestic Animals and Tsetse Fly Vectors to Control Nagana and Accelerate Elimination of Acute Sleeping Sickness from Hot Spot Villages of Eastern Uganda
REFNo: A107ES
The main objective of this study will be to determine whether targeting hotspot villages would accelerate elimination of rHAT
The specific objectives of this project will be to determine;
i. If rHAT hotspot village-based interventions [two doses of diminazene aceturate 40 days apart at the beginning of the intervention and monthly RAP] will progressively reduce T. brucei s.l. reservoir in cattle and hence insidious rHAT transmission.
ii. The drivers of insidious rHAT transmission in hotspot rHAT hotspot villages in Dokolo and Kaberamaido districts.
|
Uganda |
2021-02-25 |
2024-02-25 |
Agricultural Sciences |
|
Non-degree Award |
|
NOLBERT GUMISIRIZA KAGAMBIRWE
ID:
|
Investigating how the specialized and decentralized treatment healthcare models for all forms of epilepsy in Uganda fared in the covid-19 pandemic
REFNo: HS1156ES
1. To assess the government strategy of decentralized care and treatment for persons with all forms of epilepsy in Uganda, before COVID-19.
2. To assess the effects of the COVID-19 pandemic on access to epilepsy care in Uganda
3. To assess the socio-economic and mental health effects of the COVID-19 pandemic on persons with epilepsy in Uganda.
4. To generate ideas and strategies to improve the existing models for epilepsy care in Uganda∙
|
Uganda |
2021-02-25 |
2024-02-25 |
Medical and Health Sciences |
|
Degree Award |
|
Bjorn Van Campenhout -
ID: UNCST-2020-R014080
|
Impact of Covid-19 on maize and dairy value chains in Uganda
REFNo: SS699ES
Specific objective: To assess the impact of Covid-19 on the maize and dairy value chain in Uganda.
Specific objective: to determine how the COVID-19 pandemic affected production, marketing/sales and welfare of actors/households along the two value chains.
|
Belgium |
2021-02-25 |
2024-02-25 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
Godfrey Ejuu
ID: UNCST-2021-R013978
|
Effectiveness of Inclusive Home-based Early Learning Model in Increasing Access to Early Child Education (ECE) for Children in Marginalised Communities
REFNo: SS740ES
1. To describe contextually relevant pedagogical practices that result into better child school readiness outcomes in home based ECCE centres
2. To compare the impact of the play- based ECCE curriculum model program on children’s school readiness relative to the control group
3. To determine the impact of pedagogical mentorship program on teacher professional well-being, classroom quality, and children’s school readiness relative to a control group
|
Uganda |
2021-02-25 |
2024-02-25 |
Social Science and Humanities |
|
Non-degree Award |
|
Eddy Walakira Joshua
ID: UNCST-2022-R009077
|
SITUATION ANALYSIS OF THE IMPACT OF COVID - 19 ON GLOBAL FUND TO END MODERN SLAVERY’S SUPPORTED PROGRAMMES TO END COMMERCIAL SEX EXPLOITATION OF CHILDREN AND ENDING LABOUR EXPLOITATION
REFNo: SS757ES
This is a program evaluation study focusing on CSEC and OLR programs. As a result, the primary questions are divided into two corresponding to the two study sub-components.
Broadly, this study seeks to establish the likely impact of COVID 19 on the implementation of the Commercial and Sex Exploitation programmes supported by the Global Fund to End Modern Slavery, in Kampala and Karamoja areas.
|
Uganda |
2021-02-25 |
2024-02-25 |
Social Science and Humanities |
|
Non-degree Award |
|
Samwel Wangombe
ID:
|
INTERNAL CONTROLS, REGULATORY MECHANISMS AND FINANCIAL ACCOUNTABILITY IN INDIGENOUS NON-PROFIT ORGANISATIONS IN UGANDA
REFNo: SS734ES
1. Describe the accounting internal controls applicable to indigenous non-profit organisations.
2. Determine the significance of accounting internal controls on the level of compliance with legal and/or regulatory requirements.
3. Determine the significance of accounting internal controls on the choice of self-regulatory mechanism.
4. Evaluate the extent to which resource dependence theory determines the quality and consistency of financial reporting.
5. Explain the relationship between internal controls, regulatory mechanisms and financial accountability.
|
Kenya |
2021-02-24 |
2024-02-24 |
Social Science and Humanities |
|
Degree Award |
|
Murungi Elizabeth Mwebesa
ID:
|
Creating an Ecosystem exemplifying Cross Sector Cooperation Approach towards road safety of motorcycles in Kampala, Uganda
REFNo: SIR43ES
Each safe riding behavior belongs to either Priority (P), Speed (S) or Comprehension (C). So it is imperative to understand which factors affect which behavior and the extent of this effect.Therefore the objectives of this study are;
a)To identify the PPM (Push, Pull, Mooring) factors that promote each of the safe riding behaviors (PSC component).
b)To understand the extent to which push, pull and mooring factors influence the behavior of riders that have had contact with these parameters and those that haven’t.
c)To create a Theory of Change (ToC) model to propose the possible road map to changing the behaviors of riders. Leveraging on these two results above, a proposal of the possible road map to changing the behavior of riders will be made by creating a Theory of Change (ToC) table
|
Uganda |
2021-02-24 |
2024-02-24 |
Engineering and Technology |
|
Degree Award |
|
Goretty Nagawa Mary
ID:
|
Implications of Land Use and Land Cover Changes towards Household Food Security in the Forested and Grassland areas of Mount Elgon Slopes
REFNo: NS122ES
Overall aim of the study
The study seeks to analyze land use and cover changes; and to establish the contribution of this towards carbon emission levels, and climate variations; and to assess the implication towards household food security by looking at the quality, diversity and quantity acquisition procedures within the households of Mount Elgon slopes.
1.3.2 Specific objectives
1. To analyse land use and cover changes on Mt Elgon slopes and assess their impact on CO2 effluxes from the soil in forest and grass land cover/use types.
2. To assess climate variability in relation to land use and land cover changes; and CO2 effluxes in the forested and grassland areas of Mt Elgon Slopes.
3. To assess the impact of land use and cover changes on household food security on Mount Elgon slopes.
|
Uganda |
2021-02-24 |
2024-02-24 |
Natural Sciences |
|
Degree Award |
|
Emanuele Colonnelli
ID:
|
Do Corruption Perceptions Kill Competition?
REFNo: SS654ES
Increasing competition in public procurement is a key priority in many developing countries. High and widespread participation in the public procurement market is crucial to ensure the proper functioning of the procurement system, and ultimately high quality public investment. Public procurement of goods and services represents the primary area of government investment, accounting for 14.5% of GDP in low-income countries.
In this study, which takes place in Uganda, we aim to study the role played by a key potential barrier to competition in the public procurement market: firms' perception of public procurement as a rigged system, driven by bureaucratic corruption and personal connections. If these perceptions are widespread among market participants, governments may find it challenging to increase competition for public procurement. Furthermore, if perceptions spillover across public bodies, perceptions of systemic corruption may negatively affect competition even in those public bodies which manage to achieve high performance standards. This may in turn hinder bureaucrats' incentive to increase the performance of their organization, since efforts to reform a public body may not directly map into better perceptions of it among the public.
|
Italy |
2021-02-24 |
2024-02-24 |
Social Science and Humanities |
|
Non-degree Award |
|
Cissy Kityo
ID: UNCST-2021-R013663
|
A Phase 3b, Randomized, Multicentre, Open-Label Study Evaluating the Efficacy, Safety, and Tolerability of Switching to Long-Acting Cabotegravir Plus Long-Acting Rilpivirine From Current Antiretroviral Regimen in HIV-1 Infected, Virological Suppressed Adults in Sub-Saharan Africa. (Cabotegravir And Rilpivirine: Efficacy and Safety Study: The CARES Study)
REFNo: HS1117ES
1.To demonstrate the non-inferior antiviral
activity of switching to IM RPV LA+CAB
LA administered every 2 months compared
with continuation of cART administered
daily over 12 months in HIV-1 infected
participants in a resource limited setting.
2.To demonstrate the antiviral and
immunologic activity of switching to IM
RPV LA+CAB LA every 2 months
compared to continuation of cART over 12
and 24 months of follow-up
3.To evaluate the safety and tolerability of
switching to RPV LA+CAB LA every 2
months compared to continuation of cART.
4.To assess viral resistance in participants
experiencing protocol-defined confirmed
virologic failure (plasma HIV-1 RNA ≥200
c/mL).
5.To assess the incidence of on-treatment
genotypic resistance to CAB, RPV and
other on-study cART up to Month 12 and
24.
|
Uganda |
2021-02-24 |
2024-02-24 |
Medical and Health Sciences |
|
Non-degree Award |
|
Joaniter Nankabirwa Immaculate
ID: UNCST-2021-R012896
|
Evaluation of the household-level impact of a single round of intermittent preventive treatment of malaria in schoolchildren: A randomized study
REFNo: HS1123ES
1. To determine the impact of intermittent preventive treatment of malaria in schoolchildren on malaria transmission at the household, as measured by the prevalence of parasitaemia at the household level.
2.To determine the impact of intermittent preventive treatment of malaria in schoolchildren on the health of the children as measured by the prevalence of parasitaemia among the children.
|
Uganda |
2021-02-24 |
2024-02-24 |
Medical and Health Sciences |
|
Non-degree Award |
|
Cathy Green Louise
ID:
|
An Investigation into the Impact on Social Inclusion of High Volume Transport (HVT) Corridors and Potential Solutions to Identifying and Preventing Human Trafficking
REFNo: SS704ES
1. To investigate the role played by HVT corridors in human trafficking in Uganda and Tanzania;
2. To explore some of the factors (primarily transport-related and regulatory) that are contributing to human trafficking along HVT corridors (roads);
3. To assess the level of awareness of human trafficking and its impacts among transport providers, the users of HVT corridors, and the communities through which these routes pass;
4. To identify and recommend pilot innovations that can help recognise and counter human trafficking along HVT corridors.
|
UK |
2021-02-24 |
2024-02-24 |
Social Science and Humanities |
|
Non-degree Award |
|
Beatrice Achan
ID:
|
Epidemiology of Invasive Fungal Diseases in Uganda
REFNo: HS1127ES
1. Estimate the prevalence of fungemia due to Candida, Cryptococcus and Aspergillus species.
2. Describe the host and environmental factors associated with fungemia.
3. Determine the antifungal resistance profiles of the isolated fungal pathogens.
4. Determine the molecular ecology of Cryptococcus species causing cryptococcal meningitis.
5. Estimate the prevalence of mycetoma in Uganda.
|
Uganda |
2021-02-24 |
2024-02-24 |
Medical and Health Sciences |
|
Non-degree Award |
|
Noble Banadda
ID:
|
Unlocking resilience benefits from African water resources (RESBEN)
REFNo: A112ES
1. To establish and develop the ARUA Water CoE as an effective, high performance, research hub & nodes network of African researchers & post graduate students
2.To establish a common intellectual grounding and poastgraduate supervision capabilities in complex social ecological systems and transdisciplinarity
3. To recognise the primary and secondary research strength
4. To locate the primary and secondary research strengths in relation to the SDGs
|
Uganda |
2021-02-24 |
2024-02-24 |
Agricultural Sciences |
|
Non-degree Award |
|
Christine Wiltshire Sekaggya
ID: UNCST-2019-R000578
|
A phase II trial to describe the pharmacokinetics, safety and efficacy of pharmacogenetics-guided dosing of isoniazid in patients with HIV-associated TB
REFNo: HS1159ES
• To describe the pharmacokinetics of isoniazid, given at a higher dose (10mg/kg) among patients with fast or intermediate NAT2 acetylator status and a standard dose (5mg/kg) among patients with slow NAT2 acetylator status, among patients with HIV and drug sensitive TB.
• To investigate the safety of pharmacogenetically-determined isoniazid dosing among TB-HIV co-infected patients with drug sensitive TB.
• To explore the efficacy of isoniazid among TB-HIV co-infected patients with drug sensitive TB receiving pharmacogenetically-determined dosing, using pharmacokinetic – pharmacodynamic (PK-PD) models.
|
Uganda |
2021-02-24 |
2024-02-24 |
Medical and Health Sciences |
|
Non-degree Award |
.png)
|
Olive Kobusingye Chifefe
ID:
|
Observational Studies on Helmet Use, Speeding, Seat-Belt and Child Restraint in Kampala, Uganda
REFNo: HS1178ES
Main objective:
To establish the prevalence of road traffic crash severity risk factors in Kampala city namely speed, use of helmet use, seat-belt use, and drink- driving to generate evidence that can be used to inform policy and implementation strategies to promote road safety.
Specific objectives:
1. To assess the prevalence of seat-belt use and child restraint use among car occupants in Kampala.
2. To determine the prevalence of helmet use among motorcyclists in Kampala
3. To establish the prevalence and extent of speeding in Kampala
4. To determine the level of drink-driving in Kampala
|
Uganda |
2021-02-24 |
2024-02-24 |
Medical and Health Sciences |
|
Non-degree Award |
|
Karugahe Wilber
ID:
|
Identifying psychosocial impact of COVID-19 and promising practices for meeting the mental health and protection needs to SGBV of vulnerable populations during a protracted crisis in Kampala Slums
REFNo: SS721ES
1. Identification of psychosocial and mental health issues/problems for potential SGBV victims as a result of COVID-19 pandemic.
2. To examine the relationship that exists between psychosocial and mental health issues, Sexual Gender based violence and Coping strategies among potential SGBV victims.
3. Identify the coping strategies to help potential SGBV victims to improve their mental health, avoid prevent its occurrence or re-occurrence.
|
Uganda |
2021-02-24 |
2024-02-24 |
Social Science and Humanities |
|
Non-degree Award |
|
Mohammed Lamorde
ID: UNCST-2019-R001293
|
COVID-19 in people living with HIV: Evaluation of risk factors and outcomes in resource-limited settings
REFNo: HS1192ES
To characterize the clinical features and course of symptomatic COVID-19 in PLWH, described overall and by HIV and comorbid disease factors including pregnancy status
|
Nigeria |
2021-02-24 |
2024-02-24 |
Medical and Health Sciences |
|
Non-degree Award |
|
| View |
|
Sort By: |
|
|
|
| |
|