Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Bruce Kirenga J
ID: UNCST-2019-R001460
 INVENTORY, EFFECTIVENESS, AND SAFETY OF NOTIFIED NATURAL MEDICINES FOR THE TREATMENT OF DIABETES IN UGANDA: A PROSPECTIVE OBSERVATIONAL STUDY. A CONAT PROGRAM
REFNo: HS4356ES

The general objective is to create an inventory of NDA-notified natural or herbal medicines commonly used in the management of diabetes in adult patients in Uganda, and evaluate their preliminary effectiveness and safety Specific objectives are: 1. To establish the NDA-notified natural or herbal medicines commonly used in the management of DM among adults in Uganda 2. To determine the preliminary effectiveness of the NDA-notified natural or herbal medicines in lowering blood glucose levels when used in isolation or as complementary to conventional DM medicines 3. To assess the effect of the NDA-notified natural or herbal medicines on specific cardiometabolic characteristics of adult patients with DM in Uganda, when used in isolation or as complementary to conventional DM medicine 4. To determine the safety profile of the NDA-notified natural or herbal medicines when used in isolation or as complementary to conventional DM medicine in adult patients in Uganda
 Uganda 2024-07-02 12:54:13 2027-07-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
DAVID KITYA
ID: UNCST-2022-R009620
 ENHANCING PATIENT TRIAGE FOR NEUROSURGICAL CARE: A MIXED METHODS APPROACH
REFNo: HS4184ES

3. To design a patient triage model that accounts for criticality, resource availability, and healthcare costs.,2. To determine the key factors affecting patient triage decisions in neurosurgical care.,1. To assess the current patient triage system in neurosurgical care and identify its strengths and weaknesses.,The general objective of this research is to assess the current patient triage system in neurosurgical care, identifying its strengths and weaknesses in Uganda and Nigeria. ,
 Uganda 2024-07-02 12:52:48 2027-07-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Elliott Collins
ID: UNCST-2024-R005211
 Measuring the Impact of Group Loans and Digitized Ledgers on Savings Group Participants in Uganda
REFNo: SS2731ES

Measure the impact of savings group ledger digitization on savings group efficiency, savings behavior, and social cohesion.,Measure the impact of FAST loans on savings group participants’ access to financial services and livelihood outcomes.,
 USA 2024-07-02 12:50:51 2027-07-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Juliet Mpendo
ID: UNCST-2024-R004147
 Long-Term Follow-Up of CAB LA for Participants in HPTN 083 and HPTN 084 CAB PrEP Studies at Risk of HIV Acquisition
REFNo: HS4092ES

• To describe new HIV infections in adult and adolescent participants at risk of HIV acquisition included in the HPTN 083 and HPTN 084 studies and their associated sub-studies.
Endpoints
• Number and characteristics of new HIV infections, including detection of resistance to CAB while on study. Secondary.
Secondary Objectives
• To describe any serious adverse events (SAEs), Grade 3 and Grade 4 ISRs, and AEs leading to withdrawal in adult and adolescent participants included in the HPTN 083 and HPTN 084 studies and their associated sub-studies.
Endpoints
• Incidence and severity of serious adverse events, Grade 3 and Grade 4 ISRs, and any clinical or laboratory adverse events leading to discontinuation of CAB while on study.

 Uganda 2024-07-02 12:49:10 2027-07-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rebecca Nandutu
ID:
EXPLORING THE DEVELOPMENT OF SCIENCE PROCESS SKILLS IN THE TEACHING OF MATHEMATICS EDUCATION IN TEACHER TRAINING INSTITUTIONS IN EASTERN UGANDA
REFNo: SS2566ES


1. To assess mathematics tutor’s understanding of science process skills in teacher training institutions
2. To find out science process skills developed by mathematics tutors in teacher training institutions
3. To examine the role of mathematics tutors in developing science process skills among teacher trainees in teacher training institutions

Uganda 2024-07-02 12:46:47 2027-07-02 Social Science and Humanities Non-Clinical Trial Degree Award
SABRINA KITAKA BAKEERA
ID: UNCST-2020-R014290
 SEARCH2: A Randomized Control Trial of Telephonic Reminders for HPV Vaccination among Adolescent Girls in Kampala, Uganda
REFNo: HS3929ES


General Objective
To conduct a randomized control trial to assess the impact of text message and automated phone reminders on HPV vaccination.

Specific Objectives:
1.To assess the impact of text message and automated phone reminders on HPV vaccination.
Sub-objectives include:
1) To assess if text message and automated phone reminders were equally effective
2) To examine subgroup effects (girl: age, site, school status [in or out of school], grade, relationship with caregiver; caregiver: age, education, employment, income, marital status, distance to health facility, language), when possible depending on the degree of variability observed
3) to assess for possible additive or subtractive effects of receiving two series of message for families of girls who may have been in the intervention for both initiation and completion

Uganda 2024-07-02 12:45:18 2027-07-02 Medical and Health Sciences Clinical Trial Non-degree Award
Elizabeth namukwaya namukwaya
ID: UNCST-2021-R013177
 PARASTOP-Paracetamol with strong opioids
REFNo: HS4423ES

To explore whether placebo with strong opioids compared to paracetamol with strong opioids changes pain intenisty for different doses of opioids, different cancers and quality of lifeintensity,To establish whether placebo with strong opioids compared to paracetamol with strong opioids changes opioid related side-effects,changes in opioid requirements and global rating of improvement,To establish whether placebo with strong opioids compared to paracetamol together with strong opioids provides non-inferior analgesia for cancer related pain,To establish whether the analgesic efficacy of strong opioids after withdrawal of paracetamol is non-inferior compared the analgesic efficacy of strong opioids used together with paracetamol for cancer-related pain.,
 Uganda 2024-07-02 12:41:56 2027-07-02 Medical and Health Sciences Clinical Trial Non-degree Award
ANNY KATABAAZI  BWENGYE
ID:
GOVERNING BODIES’ FUNCTION AND PUBLIC UNIVERSITY FINANCING IN UGANDA: A CASE OF SELECTED UNIVERSITIES
REFNo: SS2708ES

1) To assess how the Adequacy and Allocative Efficiency function affects of public university financing.
2) To examine the relationship between the governing bodies’ policy function and pattern of public university financing.
3) To examine how the governing bodies’ financial function influences public university financing.
4) To determine the extent to which the governing bodies’ technical function influences public university financing.
5) To examine the challenges facing governing bodies in enhancing public university financing.
 Uganda 2024-07-02 12:40:29 2027-07-02 Social Science and Humanities Non-Clinical Trial Degree Award
Joseph Kirabira
ID: UNCST-2019-R001427
 Pediatric HIV Status Disclosure: Mental Health Outcomes, Barriers and Facilitators and Feasibility and Acceptability of Training Intervention in Improving Healthcare Workers’ Knowledge in Eastern Uganda.
REFNo: HS4017ES

1. To determine the prevalence of HIV status disclosure and association with mental health outcomes among CYALH in eastern Uganda. 2. To explore the experiences and coping mechanisms after HIV status disclosure after HIV status disclosure among young adolescents living with HIV in eastern Uganda 3. To explore the barriers and facilitators to HIV status disclosure to CYALH experienced by Healthcare workers (HCWs) in eastern Uganda . 4. To pilot and assess the feasibility and acceptability of a training intervention using WHO HIV status disclosure guidelines among HCWs to improve their knowledge about disclosure.
 Uganda 2024-07-02 12:35:50 2027-07-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Robert Kairania
ID: UNCST-2024-R016014
 Optimizing adoption and implementation of out-of-facility and clinic-based differentiated service delivery models for HIV treatment in Uganda: the OPTIONS study
REFNo: SS2776ES

Aim 1: Quantify individual-level and geographic variations in uptake of out-of-facility and clinic-based DSDM in 34 continuously surveilled communities. Approach: Using existing/secondary data from the Rakai Community Cohort Study.
Aim 2: Explore decision-making contexts and pathways to patient enrollment in out-of-facility and clinic-based differentiated HIV care models, as well as contextual and institutional determinants of DSDM adoption at clinic level.

Sub-Aim 2a: Identify modifiable conditions or mechanisms optimizing DSDM adoption in a heterogenous sample of HIV clinics.

Uganda 2024-07-02 12:33:52 2027-07-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Dorothy Nseka Kiyaga
ID:
The Role of Internal Audit on the Governance of Regulated Non-Deposit-Taking Microfinance Institutions in Uganda
REFNo: SS2778ES

iii) To construct an applied framework that may inform recommendations to institutionalize internal audits among regulated NDTMFIs in Uganda,ii) To examine the nexus within the academic literature on theories relating to corporate governance, internal audit, and microfinance,i) To investigate the role of internal audit on the governance of regulated NDTMFIs in Uganda,
 Uganda 2024-07-02 12:31:38 2027-07-02 Social Science and Humanities Non-Clinical Trial Degree Award
DAVID KITYA
ID: UNCST-2022-R009620
 Assessment of Accuracy, Precision, and Feasibility of a Handheld Near-Infrared Light Device (InfraScanner 2500™) in Detecting Intracranial Hemorrhage in Patients Admitted to Mbarara Regional Referral Hospital
REFNo: HS4141ES

Use these findings to evaluate the InfraScanner 2500™\'s ability to accurately detect intracranial hemorrhages in darker-skinned populations within LMICs. ,Determine whether the InfraScanner 2500™ detects intracranial hemorrhage (ICH) with adequate precision relative to CT scans to be used as an effective triage tool to prioritize imaging and need for level of clinical monitoring in an African, LMIC population.,To demonstrate that the InfraScanner 2500™ is capable of detecting and ruling out intracranial hematomas at rates similar to CT scan in patients hospitalized at Mbarara Regional Referral Hospital who have sustained or are suspected to have sustained head trauma.,
 Uganda 2024-06-24 0:30:16 2027-06-24 Medical and Health Sciences Clinical Trial Non-degree Award
Kirabo Suubi
ID: UNCST-2023-R005659
 Making Social Protection Interventions Work for Marginalized Women in Kenya and Uganda: Understanding the state of research evidence, women’s preferences, and policymakers’ challenges in relation to Social Protection
REFNo: SS2785ES

To understand Ugandan and Kenyan policymakers’ experiences of designing and implementing SP programs and policies as well as their evidence needs related to SP.,To understand vulnerable Kenyan and Ugandan women’s perceptions of existing SP programs in their countries, and how they think SP initiatives can be best designed and delivered to them.,To synthesize findings of previous studies on the ingredients of effective SP interventions for women. ,
 Uganda 2024-06-24 0:28:26 2027-06-24 Social Science and Humanities Non-Clinical Trial Non-degree Award
Collins Bulafu Edward
ID:
The influence of Borassus aethiopum Mart. (Arecaceae) on plant diversity in Murchison Falls National Park
REFNo: NS828ES

1. To determine the population structure of Borassus aethiopum-Mart.
2. To assess the change in plant species diversity in different abundances of Borassus aethiopum-Mart.
3. To determine influence of physio-chemical parameters of soil on plant species diversity.

 Uganda 2024-06-24 0:27:05 2027-06-24 Natural Sciences Non-Clinical Trial Non-degree Award
FRED WANYINA
ID: UNCST-2023-R006648
 ASSESSMENT OF FACTORS ASSOCIATED WITH MALNUTRITION IN CHILDREN UNDER FIVE YEARS OF AGE AT MBARARA REFERRAL HOSPITAL
REFNo: SS2349ES

iii) To assess the relationship between social demographic factors with malnutrition in children under five at Mbarara referral hospital,ii) To suggest possible solutions to malnutrition caused by climate change impacts in children below five years of age admitted at Mbarara referral hospital.,i) To examine the causes of malnutrition in children under five at Mbarara referral hospital.,The main objective of the study is to assess the factors associated with malnutrition in children under five years of age in Mbarara referral hospital. ,
 Uganda 2024-06-24 0:26:13 2027-06-24 Social Science and Humanities Non-Clinical Trial Degree Award
Kakebe Robert Sekajja
ID:
Policy Exploration for Sustainable Bioenergy Resource Production and Utilization in Uganda: A System Dynamics Modelling and Simulation Approach
REFNo: SIR294ES

d) To develop BD scenarios pathways and evaluate their policy implications to the development of the bioenergy sector in Uganda.,c) To develop the simulation model and evaluate its feasibility of functionality,b) To develop the reference BD model using the causal loop diagrams (CLD) and stock-flow diagrams (SFD) for Uganda's bioenergy sector.,a) To identify and characterize BD variables in Uganda,To determine policy options for effective and sustainable management of bioenergy resource production and utilization in Uganda by using SD modeling approach.,
 Uganda 2024-06-24 0:25:10 2027-06-24 Engineering and Technology Non-Clinical Trial Degree Award
James Galandi
ID:
Improving Agroforestry Uptake in Eastern Uganda: Practices, Technologies and Institutions
REFNo: A385ES

4.Explore the role of local institutions and stakeholders in promoting agroforestry in the region., 3.Identify the preferred agroforestry practices, tree species and technologies among farmers in the study area. , 2.Determine key impediments and opportunities for agroforestry-based climate-resilient productive system in the study area.,1.Assess the potential of agroforestry in improving farm productivity in Eastern Uganda. ,To investigate the adoption and implementation of agroforestry practices, technologies, and institutional frameworks in Eastern Uganda for sustainable agricultural development, environmental conservation and socio-economic well-being.,
 Uganda 2024-06-24 0:23:59 2027-06-24 Agricultural Sciences Non-Clinical Trial Degree Award
Ezekiel Mupere
ID: UNCST-2021-R012739
 Program Implementation and Evaluation of Integrated Maternal Child Health Nutrition Interventions in Kampala City Divisions
REFNo: SS2697ES

5. To determine the effect of integrated MCHN community interventions on MCHN outcomes/indicators in Kampala City Divisions,4. To establish stakeholders, data driven beneficiary and stakeholders’ mapping and in delivery of MCHN implementation,3. To assess the facilitators and barriers of integrated MCHN community interventions by individual beneficiaries and households in Kampala City Divisions,2. To determine the uptake and retention of integrated MCHN community interventions by individual beneficiaries and households in Kampala City Divisions,1. To assess the knowledge, attitude and practices of community village health teams, opinion leaders, beneficiaries, and facility focal persons towards integrated MCHN community interventions in Kampala City Divisions,3. To strengthen the enabling environment to deliver prevention and lifesaving interventions for optimal MCHN outcomes in Kampala City Health Divisions,2. To enhance community detection, referral and follow-up of maternal new-born, child and adolescent malnutrition in Kampala City Health Divisions to avert default and early deaths,1. To strengthen the capacity of community-facility linkages to deliver prevention and lifesaving interventions for optimal maternal new-born child and adolescent nutrition (MCHN) outcomes in Kampala City Health Divisions,To improve optimal maternal child health and nutrition (MCHN) outcomes in urban populations in Kampala City,
 Uganda 2024-06-24 0:21:19 2027-06-24 Social Science and Humanities Non-Clinical Trial Non-degree Award
Juliet Kiguli
ID: UNCST-2020-R014547
 The impact of the COVID-19 pandemic on GBV among women and girls in informal settlements in Kampala.
REFNo: SS1944ES

4. To explore the acceptability of the safe bangle innovation as a solution to GBV among at risk women and girls in informal settlements.,3. To determine the effects of COVID-19 related GBV on the mental health of women and girls in informal settlements in Kampala.,2. To identify socio-economic factors that are associated with GBV/IPV among women and girls during the COVID-19 pandemic. ,1. To estimate the prevalence of GBV/IPV among women and girls in informal settlements during the pandemic.,The main objective of this project is to explore the impact of COVID-19 on GBV among women and girls in informal settlements in Kampala, with a view to identifying entry points for testing the “SafeBangle ” innovation and other interventions to reduce IPV/GBV.,
 Uganda 2024-06-24 0:19:57 2027-06-24 Social Science and Humanities Non-Clinical Trial Non-degree Award
Andrew Mujugira
ID: UNCST-2019-R000871
 BROTHEL-BASED PrEP DELIVERY FOR CLIENTS OF SEX WORKERS
REFNo: HS4163ES

Aim 1: Identify PRECEDE factors that influence PrEP implementation for men who purchase sex in Uganda.

Aim 2: Offer PrEP choice to men who purchase sex at brothels and evaluate implementation and effect on PrEP use (PROCEED).

Aim 3: Use mixed methods to evaluate how choice influences PrEP use among men who purchase sex (PROCEED).
Aim 4: Estimate cost implications associated with integrating CAB LA into HIV programs.
 Uganda 2024-06-24 0:17:41 2027-06-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
DERRICK WAISWA
ID:
Acceptability of Transferring low birthweight infants less than 2500g in KAngaroo care in a low-resource setting in eastern Uganda (KAT study)
REFNo: HS3975ES

- Explore experiences and challenges faced by healthcare workers transferring infants in kangaroo care,- Explore experiences and challenges faced by mothers and care givers transferring infants in kangaroo care,- Explore attitudes of healthcare workers to transferring infants in kangaroo care,- Explore attitudes of mothers and caregivers to transferring infants in kangaroo care,This study aims to explore the attitudes, experiences and challenges faced by mothers, care givers and healthcare workers while transferring LBW babies in kangaroo care to a neonatal unit in eastern Uganda. ,
 Uganda 2024-06-24 0:15:24 2027-06-24 Medical and Health Sciences Non-Clinical Trial Degree Award
NOOR SALAT ABDI
ID:
prevalence and factors associated with iron deficiency among patients hospitalized with acute decompensated heart failure at Mbarara regional referral hospital
REFNo: HS4172ES

To determine the factors associated with iron deficiency among patients hospitalized with acute heart failure in Mbarara Regional Referral Hospital.,To determine the prevalence of iron deficiency among patients hospitalized with acute heart failure at Mbarara Regional Referral Hospital.,To determine the prevalence and the factors associated with iron deficiency among patients hospitalized with acute heart failure at Mbarara Regional Referral Hospital. ,
 Kenya 2024-06-24 0:13:44 2027-06-24 Medical and Health Sciences Non-Clinical Trial Degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
 PROTECT-APT 1 _ Master Protocol for Early Treatment and Post-Exposure Prophylaxis of COVID-19 Adaptive Platform Trial V3.0 dated 02 June 2023 and Appendix C entitled “A phase 2 safety and efficacy study of upamostat for early outpatient treatment of COVID-19” V3.0 dated 01 June, 2023
REFNo: HS3116ES

To determine if early treatment with upamostat can shorten time to sustained symptom alleviation or resolution in participants infected with SARS-CoV-2.
Uganda 2024-06-24 0:12:16 2027-06-24 Medical and Health Sciences Clinical Trial Non-degree Award
Suzanne  Kiwanuka N
ID: UNCST-2020-R014671
 EVALUATING THE EFFECTIVE USE OF DHIS-2 AND DATA TO IMPROVE PLANNING AND MONITORING OF IMMUNISATION, HIV AND AIDS, MALARIA, AND TB PROGRAMMES: A THREE COUNTRY RETROSPECTIVE STUDY IN BANGLADESH, MALI, AND UGANDA
REFNo: HS3675ES

To understand the extent to which adoption and use of DHIS2, DHIS2 packages and DHIS2 Tracker are associated with changes in health outcomes in Uganda. ,To understand the extent to which the utilization of DHIS2, DHIS2 packages, and tracker to improve health system outcomes in Uganda.,To understand the key enablers and barriers for the adoption, data use and analysis of DHIS2 packages for HTM and immunisation and DHIS2 Tracker, in Uganda,To review DHIS2 system outputs and assess the effect on data availability and data quality, in Uganda,To evaluate the effective use of DHIS2 & data tTo improve planning and monitoring of immunisation, HIV and AIDS, malaria, and TB programmes in Uganda.,
 Uganda 2024-06-24 0:08:50 2027-06-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
GORRETTI BYOMIRE
ID:
Employment and Inclusive Childcare for Mothers of Children with Disabilities in Kampala, Uganda.
REFNo: SS2360ES

The objectives of the study are as follows:
1. To assess the impact of access to inclusive childcare on the workforce participation of mothers of children with disabilities.
2. To examine the relationship between access to inclusive childcare, labor market participation, and women's economic engagement.
3. To identify barriers and challenges faced by mothers of children with disabilities in accessing inclusive childcare and participating in the workforce.
4. To explore the potential multigenerational impacts of access to inclusive childcare on women's economic empowerment.
5. To generate knowledge and recommendations to promote disability inclusion in Early Childhood Care and Development (ECCD) and expand access to quality affordable inclusive childcare.
6. To inform future work on inclusive childcare and contribute to the dialogue on disability inclusion and women's economic empowerment.

 Uganda 2024-06-24 0:07:53 2027-06-24 Social Science and Humanities Non-Clinical Trial Non-degree Award
SAMUEL JJUNJU
ID: UNCST-2023-R006269
 PREVALENCE OF KIDNEY DISEASE AND ASSOCIATED FACTORS AMONG PATIENTS WITH CHRONIC HEPATITIS B INFECTION AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS4186ES

To determine the prevalence of kidney disease among patients with chronic hepatitis B infection attending hepatitis clinic at MRRH. To determine the factors that are associated with kidney disease among chronic hepatitis B patients. To determine the correlation between urine NGAL and serum creatinine in estimating kidney function.
 Uganda 2024-06-24 0:06:00 2027-06-24 Medical and Health Sciences Non-Clinical Trial Degree Award
Francis Munyambonera Ezra
ID: UNCST-2023-R007401
 Modelling Agricultural Cooperatives Uganda, A Case Study of Kigezi Region Re: KABREC-2023-19
REFNo: SS2637ES

The purpose of this study is to investigate the impacts of Agricultural Cooperatives on farmer’s market accessibility in Kigezi Sub Region, Southwestern Uganda. ,
 Uganda 2024-06-24 0:04:02 2027-06-24 Social Science and Humanities Non-Clinical Trial Non-degree Award
Abner Baryaija Besigye
ID:
DECENTRALIZATION AND QUALITY PUBLIC HEALTHCARE SERVICE DELIVERY IN THE LOCAL GOVERNMENTS OF UGANDA: A CASE STUDY OF GREATER BUSHENYI DISTRICTS
REFNo: SS2347ES

(iv) To explore the stakeholders’ perception about the effectiveness and efficiency of quality public healthcare service delivery in Greater Bushenyi districts.,To assess the influence of political decentralization on quality public healthcare service delivery in Greater Bushenyi districts.,(ii) To assess association between administrative decentralization and quality public healthcare service delivery in Greater Bushenyi districts.,(i) To assess the effect of fiscal decentralization and the quality of public health care service delivery in the local governments of Greater Bushenyi districts.,The purpose of the study is to assess the relationship between the types of decentralization and the quality of public healthcare service delivery in the local governments of Uganda.,
 Uganda 2024-06-21 18:14:03 2027-06-21 Social Science and Humanities Non-Clinical Trial Degree Award
Godfrey  Siu
ID: UNCST-2021-R005439
 An evaluation of scaled-up implementation of the Parenting for Respectability Programme in Five Districts in Uganda
REFNo: HS4286ES

i. To evaluate the scalability and impact of the PfR programme on child maltreatment, violence against children and spousal relationships in 5 districts of Uganda
ii. To examine the factors associated with implementation success during scaled-up delivery of the PfR programme
iii. To assess the facilitators experiences, fidelity, and challenges in delivering the PfR programme during scale-up implementation
iv. Examine the cost effectiveness of PfR scale-up using incremental cost-effectiveness analyses (CEA)
v. To examine the design, perceived need, acceptability and perceived relevance of a practitioner’s course on designing and implementation of parenting interventions.

 Uganda 2024-06-21 18:10:27 2027-06-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Louis Bayo Boroa
ID:
Understanding Barriers to Immunization among Zero-dose and Under-immunized children in an Urban setting: An Exploratory Case Study in Kampala, Uganda. RefNo: SPH 2024-572
REFNo: HS4298ES

To synthesize learnings to inform division and Kampala district Reaching Every District (RED) micro-plans and the UNEPI’s Urban Immunization Strategy.,To document challenges, strategies, and lessons learned to reach zero-dose and under-immunized children among health workers and division health teams.,To describe beliefs, attitudes, and health-seeking behaviors of caregivers with zero-dose or under-immunized children in Kampala City, and their solutions to zero-dose or under-immunization.,To describe the socio-demographic characteristics of zero-dose or under-immunized children and their caregivers in Kampala City.,To profile the contextual characteristics of missed communities in Kampala.,The overall goal is to identify reasons why children in Kampala are zero-dose or under-immunized and what kind of interventions can be used to reach them effectively to inform division, district, and national immunization strategies.,
 Uganda 2024-06-21 18:07:50 2027-06-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Fred Abila
ID:
PREVALENCE AND RISK FACTORS ASSOCIATED WITH PLASMODIUM FALCIPARUM HISTIDINE-RICH PROTEINS 2/3 GENOMIC LOCI DELETIONS IN LANGO AND ACHOLI SUB-REGIONS, NORTHERN UGANDA
REFNo: HS4067ES

3. To determine the risk factors associated with PfHRP2/3 gene deletions among patients with confirmed P. falciparum malaria cases in selected health facilities in the sub regions.,2. To determine the parasite density among patients with confirmed PfHRP2/3 genes deletion in selected health facilities in Lango and Acholi Sub region, Northern Uganda,1. To determine the prevalence of suspected false-negative PfHRP2 RDT results and PfHRP2/3 genes deletion among patients with confirmed P. falciparum malaria cases in health facilities in Lango and Acholi sub regions, Northern Uganda.,To assess the prevalence and factors associated with PfHRP23 gene deletions leading to false negative PfHRP2/3 RDT results among patients with confirmed malaria in selected health facilities in Lango and Acholi Sub regions, Northern Uganda,
 Uganda 2024-06-21 18:01:59 2027-06-21 Medical and Health Sciences Non-Clinical Trial Degree Award
Stavia Turyahabwe Stavia
ID: UNCST-2022-R011373
 Tuberculosis (TB) Differentiated Service Delivery (DSD) approaches to support continuity of essential services during COVID and beyond in Uganda
REFNo: HS3122ES

5. To improve IPT coverage among children <5 years who are contacts of index TB clients in select health facilities in Kampala and Soroti regions,4. To improve identification of contacts of index TB clients in select health facilities in Kampala and Soroti regions, and improve their access to comprehensive diagnostic workup ,3. To improve TB treatment success (lower death rates, lower interruption rates, higher completion/cure rates) through implementation of DSD approaches in select health facilities in Kampala and Soroti regions ,2. To improve TB treatment initiation for newly identified TB cases through timely commencement of TB treatment in select health facilities in Kampala and Soroti regions ,1. To design and implement DSD models, to evaluate the models’ ability to effectively provide TPT and TB treatment, and to inform national TB/TPT DSD guidelines,To implement and evaluate innovative approaches and client care models to improve health care access, increase TB case detection and strengthen TB service delivery through DSD models. ,
 Uganda 2024-06-21 18:00:08 2027-06-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Charles Mukundane Godfrey
ID:
Gendered Power Relations, Food Production and Socioeconomic Livelihoods of Female Headed Households in Ankole Region
REFNo: SS2293ES

1. To examine how gendered power relations has affected food production among female headed households in Ankole Region. 2. To determine the mediating effect of food production on socioeconomic livelihoods of female headed households in Ankole Region. 3. To examine how gendered power relations has affected socioeconomic livelihoods of female headed households in Ankole Region.,To examine how gendered power relations influence food production and socioeconomic livelihoods of female headed households in Ankole Region.,
 Uganda 2024-06-21 17:58:16 2027-06-21 Social Science and Humanities Non-Clinical Trial Degree Award
Andrew Katumba
ID:
A Machine Learning-aided Platform for Point-of-Care Pregnancy Risk Assessment from 2D Ultrasound
REFNo: HS4144ES

1. To develop a predictive ML model based on ultrasound, clinical, and demographic data to categorize pregnancy risk and enable the community health worker to make appropriate and timely intervention recommendations.
2. To integrate the ML model in the image processing pipeline of a hand-held portable ultrasound system.
3. To pilot and evaluate the efficacy of the predictive and diagnostic models in managing high-risk pregnancies.

 Uganda 2024-06-21 17:54:02 2027-06-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Martin Bikorwomuhangi
ID:
INCIDENCE, INDICATIONS AND SHORT-TERM OUTCOMES OF NON-CONVENTIONAL INTRA-ABDOMINAL DRAINS AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: SS2689ES

4.To determine the association between different types of non-conventional intra-abdominal drains and short-term outcomes among patients who undergo intra-abdominal surgery at Surgical ward MRRH,3.To describe the different short-term outcomes among patients with non-conventional intra-abdominal drains among patients who undergo intra-abdominal surgery at Surgical ward MRRH,2.To document the various indications of non-conventional intra-abdominal drains among patients who undergo intra-abdominal surgery at Surgical ward MRRH,1.To determine the incidence of non-conventional intra-abdominal drains among patients who undergo intra-abdominal surgery at Surgical ward MRRH,To determine the incidence, indications and short-term outcomes of non-conventional intra-abdominal drains among patients who undergo intra-abdominal surgery at Surgical ward MRRH,
 Uganda 2024-06-21 17:53:08 2027-06-21 Social Science and Humanities Non-Clinical Trial Degree Award
Stevens Bechange
ID: UNCST-2022-R009190
 Eye Health Systems Assessment – Uganda
REFNo: HS4368ES

Examine how the above components of the eye health system recognise and address the needs of groups identified as vulnerable to exclusion from services,Assess the available eye care infrastructure,Assess the information system for eye health,Determine available medical products, vaccines and technologies for eye care,Determine available human resources for eye health,Describe eye care service delivery ,Assess the health financing mechanisms in operation,Describe the governance and leadership function ,The overall objective of this study is to examine and document the strengths and weaknesses of all components of the eye health care delivery system and health system linkages – thus providing a basis for targeted programmatic work to strengthen the eye health systems infrastructure and improving outcomes for eye conditions in Uganda.,
 Uganda 2024-06-21 17:51:54 2027-06-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
George Kasule William
ID: UNCST-2023-R006891
 EVALUATION OF NON-SPUTUM-BASED DIAGNOSTICS AND BIOMARKERS FOR DETECTION OF M. TUBERCULOSIS AMONG CHILDREN AND PEOPLE LIVING WITH HIV
REFNo: HS4344ES

To assess literature review of Mycobacterium tuberculosis biomarkers in non-invasively collected non-sputum samples of the Oral-Gut and Nasal pharynx parts of humans. To determine the diagnostic performance of novel stool-based biomarkers for detecting tuberculosis in children and among PLHIV using stool samples.To determine the diagnostic performance of breath-based biomarkers for detecting tuberculosis in children and among PLHIV.To determine the diagnostic performance of novel urine-based biomarkers for detecting tuberculosis in children and among PLHIV.To explore health workers’ and policymakers’ perceptions on the use of non-sputum-based assays for detecting tuberculosis in children and among PLHIV in Uganda.
 Uganda 2024-06-21 17:50:21 2027-06-21 Medical and Health Sciences Non-Clinical Trial Degree Award
Rose Nabirye Chalo
ID: UNCST-2020-R014645
 DEVELOPMENT OF AN INTER-PROFESSIONAL EDUCATIONAL PROGRAMME FOR THE ASSESSMENT OF MENTAL HEALTH OF PREGNANT TEENAGERS
REFNo: SS2691ES

The proposed project seeks to promote inter-professional education by developing an educational programme that will be used for inter-professional training of students in the health professions on the mental health assessment of pregnant teenagers.,
 Uganda 2024-06-21 17:48:53 2027-06-21 Social Science and Humanities Non-Clinical Trial Non-degree Award
Daniel Iraguha Ndungutse
ID: UNCST-2024-R003686
 DETECTION OF PAROXYSMAL ATRIAL FIBRILLATION AMONG RHEUMATIC HEART DISEASE REGISTRY PATIENTS AT THE UGANDA HEART INSTITUTE, A PREVENTIVE STRATEGY AGAINST STROKE
REFNo: HS4389ES

• To determine the prevalence of paroxysmal
atrial fibrillation using ambulatory ECG
monitoring among participants with severe
RHD in the Uganda Heart registry
• To determine factors associated with
paroxysmal atrial fibrillation among
participants with severe RHD in the Uganda
RHD registry

 Uganda 2024-06-21 17:47:52 2027-06-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jonathan Izudi
ID: UNCST-2019-R000469
 Integrating Tuberculosis Treatment into Community Pharmacies to improve TB/HIV outcomes in Uganda: the Community Pharmacy Tuberculosis Treatment (COPHAT) study
REFNo: HS4397ES

To evaluate the implementation and preliminary effectiveness of integrating TB treatment into community pharmacies among people with TB/HIV.,To adapt a person-centered strategy for integrating TB treatment into community pharmacies using a human-centered design methodology.,To explore the barriers and facilitators to integrating TB treatment into community pharmacies among people with TB/HIV.,The main objective of this Community Pharmacy Tuberculosis Treatment (COPHAT) study is to develop and pilot an implementation strategy focused on integrating TB treatment into community pharmacies among people with TB/HIV in Kampala, Uganda. ,
 Uganda 2024-06-21 17:46:35 2027-06-21 Medical and Health Sciences Clinical Trial Non-degree Award
JUSTINE MUKALERE
ID:
CONNECTING COMMUNITIES TO HEALTH SYSTEMS THROUGH VILLAGE HEALTH TEAMS: A TECHNOLOGY-ENABLED FRAMEWORK. A CASE OF BUGWERI, BULAMBULI, KIBUKU DISTRICTS
REFNo: SIR284ES

iii. To evaluate the designed framework to establish its applicability in connecting communities to health systems.,ii. To design a technology-enabled framework that will connect villages to health systems through Village Health Teams,i. To study the challenges faced by Village Health Teams in Kibuku, Bulambuli and Bugweri districts based on the existing framework and generate requirements,To enhance the connectivity between communities and the health systems through Village Health Teams based on a technology-enabled framework.,
 Uganda 2024-06-21 17:45:14 2027-06-21 Engineering and Technology Non-Clinical Trial Degree Award
Leticia Kyohangirwe
ID: UNCST-2024-R004144
 Determining the effect of psychiatric disorders on clinical outcomes among adolescents with HIV in Uganda over a one-year period.
REFNo: HS4120ES

The overall objective is to determine effect of psychiatric disorders on clinical outcomes among adolescents with HIV in Uganda using a longitudinal analysis approach.
 Uganda 2024-06-19 15:57:59 2027-06-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Kearsley Stewart
ID: UNCST-2021-R011830
 Addressing Sickle Cell Disease in Uganda: A Multi-Sectoral Approach
REFNo: HS4276ES

Aim 3: We aim to assess the current digital capacity (smart mobile phone access, internet access, data security, access to data) of KHCIV sickle cell patients, their caregivers, and KHCIV clinic staff in order to understand their preparedness for using mobile applications to improve sickle cell disease care. We seek to identify facilitators and barriers to uptake of mHealth tools and interventions, including Nanbar Health for patients and SCD Toolbox for KHCIV providers. In addition, we aim to determine the feasibility of using the Nanbar Health and SCD Toolbox mobile applications in Kalangala District and propose solutions for adaptation to enhance sickle cell care and improve outcomes beyond Kalangala District for others in Uganda. ,Aim 2: We aim to improve clinical monitoring of home-based adherence to hydroxyurea by exploring the feasibility and acceptability of using a rapid point-of-care electrophoresis sickle cell test (Gazelle) to monitor fetal hemoglobin for sickle cell patients taking hydroxyurea at their quarterly clinic visits to KHCIV. In addition, we aim to understand the facilitators and barriers to successful home-based adherence to hydroxyurea through a home visit to interview patient and caregivers about their adherence-related behaviors and observe conditions in the home that directly influence adherence to hydroxyurea, such as pill storage. ,Aim 1: We aim to explore the facilitators and barriers to uptake of newborn screening at KHCIV at a time when the Government of Uganda is scaling up newborn sickle cell testing across the country. We will describe the challenges for staff at a remote government health care facility to scale up newborn sickle cell testing. We will study parental perspectives on newborn sickle cell testing and their experiences with the current standard-of-care (dried blood spots) sent by KHCIV to the Central Public Health Laboratory in Kampala.,This study aims to reduce the burden of SCD in Uganda through a multi-sectoral study of the facilitators and barriers to: scale-up of universal newborn screening, adherence to treatments such as hydroxyurea, and improved access to sickle cell health education through mHealth digital apps. ,
 USA 2024-06-18 11:20:00 2027-06-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Fred Nalugoda
ID: UNCST-2021-R013343
 The Rakai Orphans in Communities (ROC)
REFNo: SS2744ES

The specific aims are to:
1. Define, over time, the potentially changing impact of orphanhood on HIV risk factors and HIV infection among AYA from RCCS Rounds 6-23 (1999-2027).
2. Explore issues related to mechanism and measurement to better understand the population burden of orphanhood among AYA. Key issues include 1-timing of orphaning (i.e., age they became an orphan), 2-influence of orphanhood vs. parental absence from the household, 3-the burden of orphanhood over time among children 0-14 years, and 4-validating the route of transmission (behavioral vs. perinatal) among adolescents first entering the RCCS.
3. Through life history interviews, explore the mechanisms by which orphanhood and age at orphaning may influence HIV risk among AYA and adolescent social outcomes and to assess how programs can be tailored to meet the needs of this vulnerable population. Interviews will be conducted with youth and their adult caretakers; each should be able to differentially report on events and circumstances of the orphaning period.
4. Estimate the economic impact of declining HIV-related orphanhood on youth, families, and communities. In a cost-benefit analysis, we will examine benefits of declining orphanhood (decreased adult mortality, decreased orphanhood, increased educational status, decreased HIV infection among youth) and costs (costs for ART, MMC).
Uganda 2024-06-17 11:41:08 2027-06-17 Social Science and Humanities Non-Clinical Trial Non-degree Award
John Ekure
ID:
LONG-TERM OUTCOMES OF THE MANAGEMENT OF OPEN FRACTURES AT KUMI ORTHOPAEDIC CENTER: A RETROSPECTIVE AND PROSPECTIVE LONGITUDINAL STUDY
REFNo: HS3238ES

To prospectively determine the long-term outcomes of management of open fractures of long bones at KOC from Sept 2023 to Sept 2033.,To retrospectively determine the long-term outcomes of the management of open fractures of long bones at Kumi Orthopaedic Center from 2010 to 2022.,to retrospectively and prospectively determine the long-term outcomes of the management of open fractures of long bones using surgical techniques at Kumi Orthopaedic Center.,
 Uganda 2024-06-12 15:43:48 2027-06-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Philip  Tibenderana
ID:
Spatiotemporal assessment of roof-harvested rainwater quality in Kigezi Highlands
REFNo: SIR259ES

iii) Establish a correlation matrix between retention time and water quality,ii) Determine the level of purity of roof-harvested rainwater from different rooftops and tank materials as compared with the WHO and Uganda drinking water standards;,i) Evaluate the physical, chemical and bacteriological water quality of the samples of harvested and stored rainwater,The overall objective ofTo investigate the spatiotemporal variability in quality of roof-harvested rainwater in Kigezi Highlands, Uganda.,
 Uganda 2024-06-12 15:41:10 2027-06-12 Engineering and Technology Non-Clinical Trial Non-degree Award
Aaron Sandel
ID:
Deep bonding: A new science of affect in wild primates
REFNo: NS805ES

Initiate a new paradigm for studying relationships in wild primates through the scientific study of “emotions” or affective states. Study three key species for investigating social bonds: chimpanzees and baboons in Kibale National Park and gorillas in Bwindi Impenetrable National Park. We will combine behaviour, hormones, and psychophysiology methods. This builds on my long-term study of chimpanzees at Ngogo (The development of social bonds in male chimpanzees).
 USA 2024-06-12 15:39:23 2027-06-12 Natural Sciences Non-Clinical Trial Non-degree Award
George Mukose
ID:
Public-Private Partneships Stopgap and the Performance of Universasl Secondary Educstion in Uganda
REFNo: SS2217ES

To evaluate the performance of Universal Seconadry Education under Public-Private Partnerships Stopgap,Explore the perceptions of stakeholders about the Perfomance of Universal Secondary Education under the Public-Private Partnerships stopgap,Assess the relevamce of the Public-Private Partnerships stopgap under Universal Secondary Education in Kamuli District,Evaluate how the Public-Private Partnerships stopgapaffected equity under the Universal Secondary Education in Kamuli District,Analyse the influence of the Public-Private Partnerships stopgap on the quality of Universal Secondary Education in Kamuli District,Examine the extent to which the Public-Private Partnerships stopgap affected access to Universal Secondary Education,
 Uganda 2024-06-12 15:38:30 2027-06-12 Social Science and Humanities Non-Clinical Trial Degree Award
Catherine Carlson
ID: UNCST-2023-R007222
 Sharing HaRT in New Expanses (SHINE)
REFNo: SS2002ES

Understand potential barriers and facilitators to future implementation and scale-up.,Explore participant characteristics (e.g., age, trafficking history, food security) that may moderate the intervention effectiveness.,Determine effectiveness of the Move with HaRT intervention on PTSD, depression, and anxiety symptoms among survivors of human trafficking in Uganda,To evaluate the mental health impact of Move with HaRT with human trafficking survivors in Uganda.,
 USA 2024-06-12 15:35:44 2027-06-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Alison Elliott
ID: UNCST-2023-R006524
 VAnguard community survey: exploring interrelationships between structural, social, and biological determinants of vaccine impact in Kenya and Uganda
REFNo: SS2309ES

Goal To investigate structural, social and biological determinants that hinder vaccine impact in vulnerable communities in Uganda and Kenya. Specific objectives 1. To explore structural and social determinants that hinder vaccine impact in vulnerable communities. 2. To assess the effect of biological determinants on the proxy markers of vaccine impact in vulnerable communities 3. To explore the interrelationships between structural, social and biological determinants and their combined influence on proxy markers of vaccine impact in vulnerable communities
UK 2024-06-12 15:33:11 2027-06-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Job Morukileng
ID:
Analysis of the causes and trends of deaths in Kampala City Authority Mortuary: A 5-year retrospective study 2019-2023
REFNo: HS4358ES

2. To describe the causes of deaths in Kampala city mortuary from January 2019 to December 2023.,To describe the trends of deaths in KCCA mortuary from January 2019 to December 2023,To describe the trends and causes of deaths in Kampala Capital City Authority mortuary from 2019-2023,
 Uganda 2024-06-12 15:28:21 2027-06-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
John Kamulegeya
ID: UNCST-2024-R004775
 Understanding School Health Service Provision in Uganda RefNo:IDI-REC-2024-94:
REFNo: HS4331ES

To generate evidence-based recommendations for strengthening the school health service activities, vaccination screening and HPV vaccination delivery in Uganda,To identify facilitators and barriers to HPV vaccination uptake in school-based settings amongst school administrators/teachers, healthcare workers and parents/caregivers, including key behavioral, system and social drivers and barriers.,To identify rationale for, facilitators and barriers to school-based vaccination checks and implementation of catch-up vaccination following these checks,To describe the implementation of school-based vaccination checks among a sample of primary and secondary schools in Uganda.,To generate evidence on facilitators and barriers to planning, implementation and monitoring of school health service activities.,To identify and describe best practices for cross-sectoral collaboration,To document roles of key stakeholders in school-based preventative health activities, including Community Service Organizations ,To understand the current delivery of recommended preventative school health service activities in Uganda, including provision of vaccination, health screening and health education,To understand the extent of implementation, facilitators and barriers to the current school health services in Uganda in order to generate evidence-based recommendations to inform implementation of priority activities, especially school-based vaccination checks and HPV vaccination delivery. ,
 Uganda 2024-06-12 14:28:43 2027-06-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Marion Mugisha Mutabazi
ID:
RESEARCH & LEARNING PARTNERSHIP FOR EARLY CHILDHOOD DEVELOPMENT (ECD) AND LIVELIHOODS PROJECT IN URBAN KAMPALA AND REFUGEE SETTLEMENTS IN UGANDA
REFNo: SS2623ES

1. To assess facilitators and barriers to implementation of proposed interventions and document successes and learnings. 2. To document formal and informal child care practices for children below 3 years adopted by refugee youth involved in the livelihood skilling program. 3. To measure effectiveness of program interventions (childcare, ECD and youth livelihood training) in addressing the needs of refugee youths. 4. To assess the fit of intervention delivery approach to realizing the proposed outcomes for refugee youth and their children.,
 Uganda 2024-06-12 14:25:17 2027-06-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Kennedy Kassaza
ID: UNCST-2019-R000615
 Development of a multiplex mismatch amplification mutation assay and ex-vivo cytokine release analysis to stratify Cryptococcal meningitis infections in Uganda
REFNo: HS3076ES

1. To determine the types of cytokines released in ex-vivo cytokines stimulation assay by antigens prepared from the alternate and reference alleles for the genes: CNAG_04922; CNAG_07837, CNAG_06422 and CNAG_00363.

2. To quantify the IL2 cytokine released and determine the relationship between C. neoformans gene alleles and levels of IL2 cytokine released

3. To design an allele specific PCR assay referred to as mismatch amplification mutation assay (MAMA PCR) for rapid detection of presence of alternate alleles for C. neoformans genes: CNAG_04922; CNAG_07837, CNAG_06422 and CNAG_00363 in clinical isolates
 Uganda 2024-06-12 14:23:42 2027-06-12 Medical and Health Sciences Non-Clinical Trial Degree Award
ucama Patrick ufoymungu
ID: UNCST-2023-R006573
 PERFORMANCE OF APRI SCORE COMPARED TO FIBROSCAN IN THE ASSESSMENT OF FIBROSIS AMONG ADULTS WITH CHRONIC HEPATITIS B INFECTION AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS4174ES

3. To determine the degree of agreement or disagreement between FibroScan and APRI Score in assessing the presence or absence of liver fibrosis among adults with Chronic Hepatitis B infection at the hepatitis clinic of Mbarara Regional Referral Hospital.,2. To identify the factors associated with liver fibrosis among adults with Chronic Hepatitis B infection at the hepatitis clinic of Mbarara Regional Referral Hospital.,1. To determine the prevalence of liver fibrosis among adults with chronic hepatitis B infection by using FibroScan and APRI Score at the hepatitis clinic of Mbarara Regional Referral Hospital.,To compare the performance of APRI score to Fibroscan in the assessment of fibrosis among adults with chronic hepatitis B infection at Mbarara Regional Referral Hospital.,
 Burundi 2024-06-12 14:22:59 2027-06-12 Medical and Health Sciences Non-Clinical Trial Degree Award
Orla Walsh
ID:
Staff Experiences of PAIRS Training
REFNo: HS4309ES

To determine the availability and adequacy of resuscitation equipment and supplies in the selected health centres. ,To explore the experiences of staff who have received PAIRS training and compare responses of staff within these centres who have not participated in PAIRS. ,
 Ireland 2024-06-12 14:22:12 2027-06-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Maria Kasirye Ella
ID:
INFLUENCE OF SIGNIFICANT DEPRESSION SYMPTOMS ON ADHERENCE TO TENOFOVIR BASED ANTIRETROVIRAL THERAPY AT 24 MONTHS AMONG 18 TO 35-YEAR-OLD WOMEN LIVING WITH HIV IN KAMPALA; A LONGITUDINAL STUDY
REFNo: HS4301ES

3. To determine the association between the longitudinal patterns of significant depression symptoms and adherence to ART in 18 to 35-year-old women living with HIV on Tenofovir-based regimens in Kampala district.,2. To assess the longitudinal patterns of significant depression symptoms in 18 to 35-year-old women living with HIV on Tenofovir-based regimens in Kampala district.,1. To determine the baseline prevalence of significant depression symptoms in 18 to 35-year-old women living with HIV on Tenofovir-based regimens in Kampala district.,• To determine the longitudinal patterns of significant depression symptoms and their influence on antiretroviral therapy adherence among 18 to 35-year-old women living with HIV on Tenofovir-based regimens in Kampala, Uganda.,
 Uganda 2024-06-12 14:21:19 2027-06-12 Medical and Health Sciences Non-Clinical Trial Degree Award
Job Kalema
ID: UNCST-2021-R013087
 PEER ASSESSMENT FRAMEWORK TO SUPPORT GROUP-BASED ASSESSMENT IN E-LEARNING ENVIRONMENT FOR HIGHER INSTITUTIONS OF LEARNING
REFNo: SIR341ES

To evaluate the designed peer assessment framework using the DeLone and McLean model.,To design a peer assessment framework for group-based assessment based on the requirements gathered in (i) above.,To gather the requirements of group-based assessment frameworks used in universities.,The purpose of this study is to build the peer assessment framework for group-based assessment that improves interactions in the online learning environment for Universities.,
 Uganda 2024-06-12 14:20:29 2027-06-12 Engineering and Technology Non-Clinical Trial Degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
 Validation of a cross-outbreak stigma scale in infectious disease outbreak-affected communities (2022 Ugandan Ebola outbreak component )
REFNo: SS2727ES

: Understand how stigma impacts outbreak control (and vice versa), and how this stigma could be validly and effectively assessed.,Use the stigma scale in three different outbreak contexts (specifically communities affected by Ebola in Uganda for purposes of this application) to measure disease-related stigma.,Co-develop and validate a cross-outbreak stigma scale,To administer and validate a stigma scale to assist with recognition and reduction of infectious disease outbreak-related stigma in affected communities (specifically communities affected by Ebola in Uganda).,
 Uganda 2024-06-12 14:16:19 2027-06-12 Social Science and Humanities Non-Clinical Trial Degree Award
Leonsio Matagi
ID: UNCST-2024-R004055
 The feasibility and acceptability of the co-administration of ivermectin and albendazole vs albendazole alone, in the frame of mass drug administration to school-aged children in Uganda.
REFNo: SS2755ES

To assess the feasibility (including aspects of training, materials and processes) of the co-administration of ivermectin and albendazole compared to albendazole alone at small-scale in the frame of school-based MDA in Uganda To evaluate the acceptability and identify potential barriers and enablers of the introduction of co-administered ivermectin and albendazole for beneficiaries (pupils, parents/caretakers)
 Uganda 2024-06-10 8:54:51 2027-06-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Daniela Acosta
ID: UNCST-2024-R003832
 Chimpanzee Intercommunity Competition: Measuring Benefits and Costs at the Group Level.
REFNo: NS826ES

I aim to investigate questions related to the causes and consequences of territorial expansion and contraction at the group level due to intergroup competition. Specifically, I am interested in (i) understanding changes in ranging patterns, habitat use, reproductive success, resource availability and social relationships before, during, and after territorial shifts; (ii) examining decision-making processes during patrolling behavior; and (iii) identifying the mechanisms in which sociality influences group level cooperation.
Colombia 2024-06-10 8:23:29 2027-06-10 Natural Sciences Non-Clinical Trial Degree Award
Picos Ariho
ID:
Preventive Diplomacy and the (De-)escalating Armed conflicts in Eastern Democratic Republic of Congo: A case of the International Conference of the Great Lakes Region.
REFNo: SS2620ES

1. Examine what accounts to the resurgence of the M23 Movement following its military defeat a decade ago.
2. Assess the diplomatic machinery potential of the M23 and armed conflicts.
3. Re-evaluate the promise of preventive diplomacy in both bilateral and multilateral relations with ending armed conflicts in Africa's great lakes region.
 Uganda 2024-06-06 17:41:29 2027-06-06 Social Science and Humanities Non-Clinical Trial Degree Award
Innocent Mutyaba
ID: UNCST-2021-R012218
 Identifying Predictors of Kaposi Sarcoma Immune Reconstitution Inflammatory Syndrome
REFNo: HS2151ES

We propose to utilize the ACSR ARKS study specimen biorepository and clinical database to identify predictors and biomarkers of KS-IRIS in the ARKS cohort. To determine if select clinical parameters, plasma cytokines, and KSHV burden measured at time of KS-IRIS symptom onset could serve as biomarkers of prevalent KS-IRIS. We will develop a predictive model of KS-IRIS utilizing the ARKS study to extend the findings from the HIPPOS study. To identify baseline predictors of incident KS-IRIS among adults with early-stage KS initiating ART.,
 Uganda 2024-06-06 17:40:22 2027-06-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Elisa  Macchi
ID: UNCST-2023-R004097
 Would you hire a female mechanic? Experimental evidence from motor-mechanics managers in Uganda
REFNo: SS2574ES

1. To examine the gender desparities in hiring among managers in the motor-mechanic industry.
2. To access the impact of monitoring towards gender discrimination
3. To measure the impact of training on decisions to hire and gender discrimination.
4. Measure hiring managers’ misperception about jobseekers on-the-job abilities and trustworthiness.

 Italy 2024-06-06 17:39:07 2027-06-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
Grace Kagoro
ID: UNCST-2021-R013951
 Improved mechanisms for climate change adaptation for sustainable food production
REFNo: NS705ES

Main Objective
1. To improve climate smart agriculture mechanisms and land management practices to cope with climatic variability.

Specific Objectives
1. To establish climatic related environmental hazards, risks & vulnerabilities in small holder farming of SW Uganda.
2. To determine climate smart agricultural practices for adoption to diversify and increase food production in climatic hazard-prone areas.
3. To optimize laboratory infrastructure for analytical capacities in soil, food profiling and plant micro-propagation at MUST.
4. To develop farmer-led crop production and climate monitoring systems for informed food production.
 Uganda 2024-06-05 17:47:58 2027-06-05 Natural Sciences Non-Clinical Trial Degree Award
Linda Calabrese
ID:
Comparative analysis of FDI in Uganda
REFNo: SS1960ES

This research aims to understand whether investment from China is different from that from other countries in terms of its implications for host low- and middle-income countries (LMICs). I operationalise the research in the context of the spillovers generated by Chinese firms and foreign-non Chinese firms on domestic firms. I focus on spillovers because these are important channels of durable productivity transfers between foreign and domestic firms, but one that has mainly been investigated quantitatively and with little comparative analysis.
 Italy 2024-06-05 17:46:42 2027-06-05 Social Science and Humanities Non-Clinical Trial Degree Award
PAULA NJERU
ID:
Utility of An Epilepsy Self-Management And Resilience Technical (SMART) APP for Adolescents and Young Adults
REFNo: HS3799ES

To identify specific improvements for the APP that will make it more useful for AWE and young adults.,To understand aspects of the APP that AWE and young adults derive the greatest benefit from.,To understand the perspectives of adolescents and young adults with epilepsy about using the SMART APP. ,To characterize the experiences of adolescents and young adults with epilepsy while using the SMART APP, pinpoint the essential elements of the APP that adolescents and young adults with epilepsy find most advantageous, and propose specific enhancements to further improve the APP,
 Kenya 2024-06-05 17:45:41 2027-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Richard Rwabuhinga
ID:
Influence of Competency and performance on Employability in Uganda; A case study of Mountains of the Moon and United Pentecostal Universities
REFNo: HS3058ES

4. The establish the impact of competencies on interpersonal skills of graduates from Mountains of the Moon and United Pentecostal Universities in Mid-western Uganda,3. To find out the influence of competence on problem solving skills of education graduates from Mountains of the Moon and United Pentecostal Universities in Mid-western Uganda.,2. To establish the influence of competence on communication skills among education graduates from Mountains of the Moon and United Pentecostal Universities in Mid-western Uganda.,1. To establish the influence of competence on academic skills among education graduates from Mountains of the Moon and United Pentecostal Universities in Mid-western Uganda.,
 Uganda 2024-06-05 17:44:09 2027-06-05 Medical and Health Sciences Non-Clinical Trial Degree Award
Cissy  Kityo
ID: UNCST-2021-R013663
 A Phase 2a/2b Study Evaluating Safety, Immunogenicity, and Therapeutic Efficacy of ID93 + GLA-SE Vaccination in Participants with Rifampicin-Susceptible Pulmonary TB
REFNo: HS3834ES

1.2 Secondary Objectives 1.2.1 Phase 2a and 2b: To evaluate the proportion of participants with a quantifiable RS ratio after therapeutic vaccination with ID93 + GLA-SE compared to placebo. 1.2.2 Phase 2a: To evaluate the kinetics of cellular immunogenicity of ID93 + GLA-SE through 12 months post second dose of study product. 1.2.3 Phase 2a: To evaluate the kinetics of humoral immunogenicity of ID93 + GLA-SE through 12 months post second dose of study product. 1.2.4 Phase 2a: To evaluate innate immune changes in response to ID93 + GLA-SE through 2 weeks post second dose of study product. 1.2.5 Phase 2b: To compare therapeutic vaccination with ID93 + GLA-SE, to placebo, with respect to the proportion of participants with TB-related unfavorable outcomes at 540 days after study entry, which is approximately 18 months after start of TB treatment, in subgroups defined by: Hard-to-treat phenotype and not hard-to-treat phenotype, where hard-to-treat phenotype is defined as smear Grade ≥3 and cavitary disease on chest radiograph at TB diagnosis.1.3 Exploratory Objectives 1.3.1 Phase 2a: To compare therapeutic vaccination with ID93 + GLA-SE to placebo, with respect to: • The safety and immunogenicity of ID93 + GLA-SE in participants living with and without HIV. • The quantitative RS ratio at time points relative to vaccination and TB treatment as indicated in the Schedule of Evaluations (SOE). • The magnitude and quality of immune responses with respect to the composition of the intestinal microbiota. 1.3.2 Phase 2b: To compare therapeutic vaccination with ID93 + GLA-SE to placebo, with respect to the proportion of participants with TB-related unfavorable outcomes at 540 days after study entry, which is approximately 18 months after start of TB treatment, adjusted for • Pharmacokinetics (PK) assessments of first-line TB drugs (exposure) during TB treatment as per the SOE. • Levels of participant adherence to standard of care (SOC) TB treatment measured using self-reporting and urine acetyl-isoniazid (AcINH) from start to end of TB treatment. 1.3.3 Phase 2b: To compare therapeutic vaccination with ID93 + GLA-SE to placebo, with respect to the proportion of participants with TB-related unfavorable outcomes at 540 days after study entry, which is approximately 18 months after start of TB treatment, stratified by bacterial burden at start of TB treatment. 1.3.4 Phase 2a and 2b: To develop the composite predictive model of TB drug response by using measures of adherence, drug exposure (PK), immune response, gut microbiota, and participant phenotype. 1.3.5 Phase 2a and 2b: To compare therapeutic vaccination with ID93 + GLA-SE to placebo, with respect to proportion of participants with sputum culture conversion at baseline at time of randomization and at Step 2, Days 30, 120, and 150, which are approximately 2, 5, and 6 months after start of TB treatment. 1.3.6 Phase 2a and 2b: To compare therapeutic vaccination with ID93 + GLA-SE to placebo, with respect to cumulative relapse from end of TB treatment up to end of study follow-up, that is, Step 2, Days 420, 450, 480, and 510, for Groups 1, 2, 3 (&5), and 4 (&5), respectively. 1.3.7 Phase 2a and 2b: To compare therapeutic vaccination with ID93 + GLA-SE to placebo, with respect to lung function and health-related quality of life, as measured by spirometry and the St. George’s Respiratory Questionnaire. 1.3.8 Phase 2a and 2b: To compare the within-person change in lung function tests over time from the first dose of therapeutic vaccination with ID93 + GLA-SE to placebo. 1.3.9 Phase 2a and 2b: To compare therapeutic vaccination with ID93 + GLA-SE to placebo, with respect to resolution of transcriptomic biomarkers of TB disease. 1.3.10 Phase 2b: To identify correlates of protection for unfavorable TB outcomes. 1.3.11 Phase 2b: To estimate the effect of the vaccine on the proportion of participants with TB-related unfavorable outcomes among participants living with and without HIV. 1.3.12 Phase 2a and 2b: To conduct analyses related to furthering the understanding of TB, HIV, immunology, vaccines, and clinical trial conduct.,1.1 Primary Objectives 1.1.1 Phase 2a and 2b: To evaluate safety of a two-dose ID93 + GLA-SE vaccine regimen administered 60 days apart on Step 2, Days 0 and 60, with TB treatment administered, at approximately: 1.1.1.1 Months 4 and 6 after start of TB treatment (Group 1) 1.1.1.2 Months 3 and 5 after start of TB treatment (Group 2) 1.1.1.3 Months 2 and 4 after start of TB treatment (Group 3 and Group 5, if this vaccination schedule is adopted for Group 5) 1.1.1.4 Months 1 and 3 after start of TB treatment (Group 4 and Group 5, if this vaccination schedule is adopted for Group 5) 1.1.2 Phase 2a and 2b: To determine if therapeutic vaccination with ID93 + GLA-SE will increase the magnitude of vaccine-specific cellular responses compared to placebo at 2 weeks post second dose of study product. 1.1.3 Phase 2b: To estimate the effect of the vaccine on the proportion of participants with TB-related unfavorable outcomes (treatment failure, TB recurrence, or death due to TB) at Day 540 after study entry, which is approximately 18 months after start of TB treatment (Group 5 combined with either Group 3 or Group 4, depending on which vaccination schedule is selected for Group 5).,
 Uganda 2024-06-05 17:42:17 2027-06-05 Medical and Health Sciences Clinical Trial Non-degree Award
KIYINGI MARTIN
ID:
A critical review of [Nature of existence]; to establish "Existential Scope of education", the "Problem of education", "Forms of inquiry” and “Perspectives of knowledge”, in Uganda. A case of selected education policy institutions and Universities in Uganda.
REFNo: SS2573ES

4. To explore possibility of Physical (Truth, Empirical Knowledge and Reality), to alleviate the prevailing and emerging, “Existential” and “Physical” problems; probably the prevailing “Scope of education” is focused at mitigation and adaptation rational consequential [Physical problems (Outcomes)] of own continuous existential Causation and Processing. ,3. To explore how the [Nature of existence] influence Existential (Truth, Knowledge & Reality) and establish if possibility of (Truth, Knowledge and Reality) is limited to only the physical possibility of existence.,2. To explore the “Problem of education” and establish how the [Existential forms of inquiry] based on the [Nature of existence] influence the [Perspectives (Viewpoint) of knowledge]. ,1. To explore the fundamental [Nature of existence], a fundamentalism of [Existential Identity] of all species, the “Scope of education” and basis for respective [Existential forms of inquiry (Sensory response to stimulus)].,
 Uganda 2024-06-05 17:39:12 2027-06-05 Social Science and Humanities Non-Clinical Trial Degree Award
Cornelius Sendagire
ID: UNCST-2021-R004351
 Potentially modifiable factors to improve outcomes of mechanically ventilated patients in ICUs in Resource-limited settings (MOTIVATE-ICU)
REFNo: HS4040ES

To assess outcomes associated with tracheostomy timing in IMV patients in LMIC ICUs.,To determine non-modifiable patient-level factors associated with ICU mortality, ICU length of stay and duration of mechanical ventilation among LMIC ICU patients. ,To identify potentially modifiable factors associated with ICU mortality, ICU length of stay and duration of mechanical ventilation among LMIC ICU patients. ,
 Uganda 2024-06-05 17:37:52 2027-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jack Turihohabwe
ID:
A deep learning model for early prediction and diagnosis of Late Blight Disease in Irish potatoes: A case of Kigezi Region RefNo:MUST-2023-1308
REFNo: SIR323ES

The major objective of the research study is improving early prediction and accurate diagnosis of late blight disease among Irish potato farmers in Kigezi.
 Uganda 2024-06-05 17:36:19 2027-06-05 Engineering and Technology Non-Clinical Trial Degree Award
Emmanuel Menya
ID:
Torrefaction of Banana Value Chain-Based Wastes Available in Uganda for Fuel (TorrCoal Project)
REFNo: SIR172ES

Main Objective
To investigate the torrefaction potential of banana value chain-based wastes available in Uganda for fuel.

Specific Objectives
• To characterize the underutilized banana value chain-based wastes
• To optimize the torrefaction conditions for production of bio-coal from selected banana value chain-based wastes
• To assess the quality and performance of briquettes generated from the torrefied banana waste
 Uganda 2024-06-05 17:35:18 2027-06-05 Engineering and Technology Non-Clinical Trial Degree Award
Adeline Boatin
ID: UNCST-2019-R001255
 Education of pregnant women with a prenatal indication for cesarean section through periodic short message service (SMS) and interactive voice response system (IVR) in Uganda
REFNo: HS4081ES

1. To pilot the use of SMS and IVR among high-risk pregnant women scheduled for elective caesarean section and receiving antenatal care at the Mbarara Regional Referral Hospital in Uganda. 2.a)To determine the acceptability of SMS and IVR among high-risk pregnant women among high risk pregnant women scheduled for elective caesarean section. 2.b)To determine the feasibility of using SMS and IVR for education among high risk pregnant women scheduled for elective caesarean section.
 Ghana 2024-06-05 17:34:20 2027-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Benson Musinguzi
ID:
MOLECULAR EPIDEMIOLOGY OF OROPHARYNGEAL CANDIDA SPECIES ISOLATED FROM PEOPLE LIVING WITH HUMAN IMMUNODEFICIENCY VIRUS ATTENDING TASO CLINICS IN UGANDA
REFNo: HS3823ES

Sub study 4. Molecular relatedness of oropharyngeal Candida species isolated from people living with HIV attending TASO clinics in Uganda.,Sub study 3. Virulence attributes in oropharyngeal Candida species isolated from people living with HIV attending TASO clinics in Uganda,,Sub study 2. Prevalence of OPC and antifungal susceptibility profile of oropharyngeal Candida species isolated from people living with HIV attending TASO clinics in Uganda, ,Sub study 1. Prevalence of oropharyngeal candidiasis and distribution of Candida species among people living with HIV in Africa: a systematic review and meta-analysis,MOLECULAR EPIDEMIOLOGY OF OROPHARYNGEAL CANDIDA SPECIES ISOLATED FROM PEOPLE LIVING WITH HUMAN IMMUNODEFICIENCY VIRUS ATTENDING TASO CLINICS IN UGANDA,
 Uganda 2024-06-05 17:31:38 2027-06-05 Medical and Health Sciences Non-Clinical Trial Degree Award
Ronald Olum
ID: UNCST-2021-R013821
 Feasibility, Acceptability and Preliminary Effect of Community-Led HIV Self-Testing Intervention Among Adolescent Girls and Young Women in Rural Northern Uganda.
REFNo: HS4043ES

To assess the preliminary impact of the peer-delivered CHW-facilitated HIVST model on HIV self-testing rates and linkage to care among AGYW. ,To evaluate the feasibility and acceptability of the peer-delivered community health worker-facilitated HIV self-testing intervention in Northern Uganda.,To develop a peer-delivered community health worker-facilitated HIV self-testing model tailored to the needs of adolescent girls and young women n Northern Uganda.,The overall aim of this study is to establish a sustainable, community-based HIV self-testing model that effectively increases HIV rates and linkage to care among adolescent girls and young women n Northern Uganda.,
 Uganda 2024-06-05 17:30:10 2027-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Peter Kangwagye
ID: UNCST-2023-R005510
 EARLY DETECTION OF ATRIAL FIBRILLATION AMONG RHEUMATIC HEART DISEASE PATIENTS WITH MODERATE OR SEVERE LESIONS IN SINUS RHYTHM
REFNo: HS4027ES

2. To document the factors associated with AF among patients attending the RHD clinic of MRRH,1. To determine the prevalence of AF among patients attending the RHD clinic of MRRH,To determine the prevalence of atrial fibrillation (AF) among patients with RHD in Mbarara Regional Referral Hospital (MRRH),
 Uganda 2024-06-05 17:26:45 2027-06-05 Medical and Health Sciences Non-Clinical Trial Degree Award
Lydia  Kabiri Watsemwa
ID: UNCST-2020-R014567
 Exploring the rationale for an integrated preventive approach to child health in Uganda: Perspectives from families, health care givers and non-health stakeholders
REFNo: HS3931ES

To understand challenges, opportunities, and possible improvements in the current system for preventive child health care in Uganda;

To explore opportunities, barriers, and facilitating factors for creating and implementing a future permanent system for preventive child health, suitable for multisectoral collaboration;

To understand how caregivers currently identifies early signs of illness and developmental delay among young children;

To understand how caregivers and other stakeholders view the possibility for improved knowledge of early signs of illness as well as early screening for and identification of developmental delay and disability among young children.

Uganda 2024-06-05 17:23:17 2027-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Zenah Nantumbwe
ID:
A Mental Health Literacy intervention for adolescents in secondary school in Uganda: Implementation and evaluation of “The Wellness Project”
REFNo: HS4071ES

To examine if The Wellness Project intervention has a positive impact on MH care referral system and explore acceptability of MHL intervention program among adolescents and key health contacts. ,To investigate if mental health literacy psychoeducational program will increase mental health - illness knowledge, reduce stigma attitudes towards mental illness and increase help seeking knowledge and intentions among adolescents. ,To access the mental health-illness knowledge, stigma attitudes towards mental illness, help seeking behaviour and school MH care of adolescents in secondary school.,
 Uganda 2024-06-05 17:21:06 2027-06-05 Medical and Health Sciences Non-Clinical Trial Degree Award
Dennis Kalibbala
ID:
Effectiveness and implementation of HIV self-testing distribution through the Young People and Adolescents Peer Support (YAPS) model in Uganda
REFNo: HS4089ES

3. To explore the effectiveness of HIVST through the YAPS model on linkage to care and treatment outcomes among those who test positive,2. To assess the acceptability and feasibility of HIVST distribution through the YAPS model among young people and adolescents in Uganda.,1. To identify the factors that influence the implementation of HIVST through the YAPS model.,To determine implementation and effectiveness of HIV self-testing through the Young People and Adolescents Peer Support (YAPS) model in Uganda,
 Uganda 2024-06-05 17:19:50 2027-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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