Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
Search By Approval Date:
Clear Filter Total: 5,779
Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
John Rek
ID: UNCST-2024-R004373
 Bednet use across a spectrum of malaria transmission risk in Tororo and Busia Uganda
REFNo: SS769ES

1. Determine household- and individual-level characteristics that correlate with poor bednet use using novel metrics from an electronic adherence monitor.
2. Relate bednet use to malaria-related outcomes such as mosquito density, malaria infection and clinical malaria episodes.
3. Develop a theoretical behavioral model of bednet adherence using qualitative interviews.
4. Compare methods for objective bednet adherence monitoring using the SmartNet platform.

Uganda 2021-03-18 2024-03-18 Social Science and Humanities Non-degree Award
Aubryn Sidle Allyn
ID:
Barriers to Returning Girls to School After COVID-19 Related School Closures in East Africa
REFNo: SS750ES

1. Identify and disseminate information about the barriers that adolescent girls in Uganda are facing that may prevent school resumption once directives to resume are given.

2. Identify and disseminate information about promising best practice programming in distance education and returning formerly school-going adolescent girls to school, once schools

USA 2021-03-18 2024-03-18 Social Science and Humanities Non-degree Award
Agnes Kiragga
ID:
Piloting a HIV Risk assessment application to increase awareness and uptake of HIV prevention services among young adults in Uganda. (SIDARISK)
REFNo: HS1293ES

• To assess the extent of high-risk sexual behavior and related practices among young adults using a web-based individualized HIV risk platform (SIDARISK)
• To establish the feasibility of using an existing telehealth platform for the referral and linkage to HIV/STI testing and prevention services following risk assessment by the SIDARISK application.
• To understand acceptability of the SIDARISK application for HIV risk assessment among young adults in Uganda
• To establish the feasibility of using a telehealth platform for provision of information on HIV risk reduction and linkage to HIV and PrEP services following using of the SIDARISK application

 Uganda 2021-03-18 2024-03-18 Medical and Health Sciences Non-degree Award
Catriona  Waitt John
ID: UNCST-2019-R001068
 Pilot feasibility study for uptake and implementation of a clinical algorithm for warfarin dosing in sub-Saharan African patients in the War-PATH Ugandan and South African clinical study sites.
REFNo: HS721ES

To evaluate whether the clinical algorithm improves anticoagulation control compared with local standards of care.
To determine the feasibility and acceptability of implementation of a clinical algorithm developed from the observational phase (phase 2) of the War-PATH study
 UK 2021-03-17 2024-03-17 Medical and Health Sciences Non-degree Award
Ben Jones
ID:
Challenging categories: educated unemployed youth as institutional innovators in rural Uganda
REFNo: SS599ES

The objective of the study is to examine participation in local institutions to challenge understandings of youth, education and
unemployment. The outputs involve academic publications and advocacy work. The target population are educated unemployed youth and actors working with local institutions, including churches and courts. By “educated unemployed youth” we mean youth who are educated up to a minimum of S4.
 UK 2021-03-17 2024-03-17 Social Science and Humanities Non-degree Award
Cissy  Kityo
ID: UNCST-2021-R013663
 Gut Integrity and Metabolic Complications in Youth Living with HIV in Uganda.
REFNo: HS1036ES

The overall objective is to use surrogate markers to investigate the interplay between intestinal integrity, microbial translocation, immune activation, systemic inflammation and metabolic comorbidities in YLPHIV residing in urban and rural settings in Uganda.
Specific Aim 1: Assess differences in gut integrity, microbial and fungal translocation markers, as well as inflammation in YLPHIV compared to HIV-uninfected controls in Kampala (urban), and Gulu (rural), Uganda.
Specific Aim 2: Assess whether markers of gut integrity, translocation and inflammation are associated with adiposity, measured by dual-energy X-ray absorptiometry (DXA) and levels of the homeostatic assessment of insulin resistance (HOMA) in YLPHIV and HIV-uninfected participants in Kampala and Gulu.
Specific Aim 3: Assess the relationship between gut and inflammatory biomarkers and diet, physical activity, socioeconomic status and air pollution.
Uganda 2021-03-17 2024-03-17 Medical and Health Sciences Non-degree Award
Christine Kiconco
ID:
Management of Agricultural Indigenous Knowledge in Agricultural Research Organizations in Uganda.
REFNo: SS739ES

1. To establish the efforts of AR4D organizations towards AIK management
2. To examine how AR4D researchers’ perceptions of AIK influence their attitudes towards AIK management
3. To assess how facilitating conditions influence AIK management efforts in AR4Ds
4. To explore strategies that can enhance AIK management in AR4Ds to prevent continued AIK loss and increase possibilities for its access and utilization in agricultural development.
 Uganda 2021-03-17 2024-03-17 Social Science and Humanities Degree Award
Shevin  Jacob Thomas
ID:
Understanding Drivers of Antimicrobial Resistance Among Mothers and Children in Uganda (DRUM+)
REFNo: HS1185ES

Understanding Drivers of Antimicrobial Resistance Among Mothers and Children in Uganda (DRUM+)
Specific Objectives:
Determine the prevalence of ESBL-E and ESBL-K bloodstream infections (BSI) and colonization among peripartum women and neonates/children < 5yo hospitalized with suspected sepsis.
2. Among peripartum women and neonates/children < 5yo hospitalized for suspected sepsis, determine the clinical outcomes, including morbidity (e.g., incidence of chronic kidney disease), mortality percentage (in-hospital and up to 4 months after the date of hospitalization) and frequency of readmission up to 4 months after the date of hospitalization.
3. Determine whether there is a molecular epidemiologic linkage between household carriage (including humans, associated domestic animals, and environment) of ESBL-E and ESBL-K AND patients (peripartum women or neonates/children < 5yo) hospitalized with sepsis who have ESBL-E and ESBL-K BSI or colonization.
4. Among patients (peripartum women or neonates/children < 5yo) hospitalized with sepsis who have ESBL-E and ESBL-K BSI or colonization, evaluate drivers of AMR transmission in Uganda (e.g., directionality of transmission and independent risk factors for transmission) using a dynamic agent-based model incorporating their microbiologic resistance data AND the data from linked households describing microbiological resistance and WASH observations.
 USA 2021-03-17 2024-03-17 Medical and Health Sciences Non-degree Award
Coleen Sabatini
ID: UNCST-2019-R001321
 Outcomes of Vascularised Fibula Flaps for Reconstruction of Segmental Bone Defects at CoRSU Rehabilitation Hospital
REFNo: HS1203ES

General Objectives To assess if vascularised fibula flap surgery for long segmental bone defects results in good outcomes for patients with an acceptable complication profile. Specific objectives 1.To determine the functional and aesthetic outcomes of vascularised fibula flaps for treatment segmental bone defects from osteomyelitis. 2.To determine outcomes of use of vascularized fibula flap in reconstruction for pseudarthrosis of the tibia, benign tumor, trauma and infection 3.To determine the complications related to the use of vascularized fibula flap in the patient populations of infection, trauma, tumour, and pseudarthrosis.
USA 2021-03-17 2024-03-17 Medical and Health Sciences Non-degree Award
Jakob Svensson
ID: UNCST-2021-R013843
 The impact of value chain participation for smallholder farmers: evidence from the coffee sector in Uganda
REFNo: SS754ES

This proposal builds on our earlier work by trying to answer a logical follow-up question. Given what we know, namely: (i) supply side interventions tend to raise adoption rates (although the effect sizes are typically modest) but at best tend to have a marginal effect on farmer income, (ii) improved market access (a demand intervention) resulted in upgrading and large positive effect on both farm profit and productivity, but quantitatively small effects on adoption rates, there may be important complementarities between the supply and demand side.

The main objective of this study is to study the impact on productivity (yield) and income (farm profit) of relaxing both supply constraints and a demand constraint (access to a market for quality produce). Or in other words, what is the impact on productivity and income of farmers gaining access to a market where quality produce is paid a premium (i.e. participates in a high-value chain) and at the same time get access to subsidized inputs? By studying such complementarities between demand and supply factors, our proposed study is unique.
Sweden 2021-03-17 2024-03-17 Social Science and Humanities Non-degree Award
Janet SEELEY
ID:
Rapid assessment of secondary school physical and social environments for menstraul health in Uganda
REFNo: HS1270ES

1)To describe the current status of schools and menstrual health programmes being implemented
2)To describe the social and physical school environment, access and type of basic WASH facilities and school facilities for illness management.
3)To develop an understanding of the interactions between school staff, students and parents and the social and physical school environment relating to menstraul health.
 UK 2021-03-17 2024-03-17 Medical and Health Sciences Non-degree Award
Herve Monka Lekuya Monka
ID:
Depressed Skull fractures: Timing of surgery, systemic inflammatory response, intraoperative blood loss, surgical site infection, and post-traumatic seizures - (DESTINE study)
REFNo: HS1284ES

5) To compare the risk of developing a delayed PTE up to 6 months of postoperative period between early and delayed surgery of DSFs ,4) To compare the risk of SSI within 3 months of postoperative period between early and delayed surgery of DSFs ,3) To compare the volume of intraoperative blood loss during the elevation of the DSFs between early and delayed surgery ,2) To compare the changes of serum levels of inflammatory cytokines among TBI patients regarding the timing of the elevation of DSFs ,1) To describe the epidemiology, clinical and radiological presentations of patients with DSFs ,This study aims to determine whether the timing of surgery of DSFs has a relationship with the changes of the biological markers of SIR, the risk of excessive intraoperative blood loss, the occurrence of SSI, and the incidence of PTE; this could optimize the clinical management of patients with head trauma in LMIC settings.,
 Democratic Republic of Congo 2021-03-17 2024-03-17 Medical and Health Sciences Degree Award
VINCENT KIBERU MICHEAL
ID:
Implementing and evaluation of a low-resource digital infrastructure in Uganda: Visualization and Interpretation of Radiographic Images (VIoRI) to improve access to imaging services at Mulago and Kayunga regional referral hospitals.
REFNo: HS1287ES

a) To determine the diagnostic accuracy (specificity and sensitivity) of ordinary core i3 PC based display systems when compared to the dedicated PACS Workstations.
b) To determine the quality of JPEG images on ordinary core i3 PC’s compared to the DICOM images generated by the PACS workstations.
c) To determine the turnaround time of patient’s diagnosis processes using ordinary core i3 PC based digital display systems relative to the PACS workstations.
d) To strengthen research capacity and collaborations with the Ministry of Health so as to allow continuity of innovative digital health research that informs improved service provision.

 Uganda 2021-03-17 2024-03-17 Medical and Health Sciences Non-degree Award
Freddy Kitutu Eric
ID: UNCST-2020-R014751
 Availability and use of essential medicines and health supplies
REFNo: HS1122ES

4. Explore the effect of centralized funding mechanism on the availability of essential medicines in private not for profit facilities,3. Assess the impact of SPARS on the quality of HMIS health facility logistics data.,2. Determine the effect of SPARS on the availability of essential medicines and health supplies in public and private not for profit health facilities,1. Determine the effect SPARS has had on medicines management practices within health facilities during the scale-up period beyond one year,
 Uganda 2021-03-16 2024-03-16 Medical and Health Sciences Non-degree Award
Achilles Katamba
ID: UNCST-2019-R000540
 Understanding the trajectories of individuals in Uganda with trace M. tuberculosis nucleic acid in sputum- The TURN-TB study (Trace Ultra Result iNsight in TB screening)
REFNo: HS1177ES

1.To characterize baseline evidence for current or past TB disease and infection among individuals with Ultra-trace-positive sputum.
2.To longitudinally evaluate the incidence of TB and the dynamics of molecular, imaging, and immunological findings among individuals with trace-positive Ultra but no active TB at study entry.
3.To quantitatively and qualitatively explore the implications of trace-positive results and associated patient trajectories for active TB case finding strategies.

Uganda 2021-03-16 2024-03-16 Medical and Health Sciences Non-degree Award
Stephen  Ojiambo Wandera
ID: UNCST-2021-R012147
 Parent-Child Communication on Sexual and Reproductive Health in border districts of Eastern Uganda
REFNo: SS748ES

The aim of the study is to assess parents’ knowledge, attitudes, and practices (KAP) and preferred approaches to PCC on sexual and reproductive health in eastern Uganda. Specific objectives are:
1. To assess parents’ knowledge, attitudes, and practices about parent-child communication about sexual and reproductive health in eastern Uganda.
2. To determine the prevalence and determinants of PCC on SRH in eastern Uganda using survey data.
3. To examine the facilitators and barriers of PCC on SRH using qualitative data among parents in eastern Uganda.
4. To identify parents’ and children’s preferred approaches to PCC on SRH in eastern Uganda.

 Uganda 2021-03-16 2024-03-16 Social Science and Humanities Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 Strategies for resolving the gap in Adolescent TB care in Uganda: A pilot cluster randomized-controlled trial
REFNo: HS1042ES

1.To develop an adolescent friendly TB screening package in Ugandan health facilities.
2.To evaluate the effectiveness of an adolescent friendly screening package for TB in Ugandan health facilities
3.To ascertain the cost effectiveness of rolling out an adolescent friendly TB screening intervention in Ugandan health facilities

 Uganda 2021-03-15 2024-03-15 Medical and Health Sciences Non-degree Award
Immaculate  Nankya Lillian
ID: UNCST-2020-R014784
 Validation of an Antigen ELISA based assay for the detection of SARS-CoV-2 RNA: A COVID-19 rapid diagnostic test method
REFNo: HS1103ES

• Demonstrate the ability of the AirJump ESP Platform, a simplified RNA isolation method to extract SARS COV-2 RNA from patient samples
• Evaluate an ELISA based assay to detect RNA converted to cDNA and bound to biotin labeled primers
• Assess accuracy of the ELISA assay in detecting SARS-CoV-2 from paired Nasal Pharyngeal swabs and saliva samples collected from COVID-19 positive and negative participants.
• Determine the Reproducibility of the Antigen ELISA Assay

 Uganda 2021-03-15 2024-03-15 Medical and Health Sciences Non-degree Award
JOSEPH SSUUNA
ID: UNCST-2024-R016102
 Epidemiology and impact of HIV, NCD and urbanization syndemic in Africa.
REFNo: HS1188ES

Aim 1: Characterize HIV-related and -unrelated risk factors for cardiopulmonary non-communicable diseases (CP-NCDs) in a novel Rural-to-Urban (R2U) African cohort.

Aim 2: Characterize the impact of air pollution and moderating effects of HIV on cardiopulmonary clinical outcomes among R2U migrants.

Aim 3: Assess HIV and CP-NCDs health services utilization patterns among R2U migrants and design an integrated HIV/CP-NCD intervention.

 Uganda 2021-03-15 2024-03-15 Medical and Health Sciences Non-degree Award
CHRISTOPHER  OPIO KENNETH
ID:
Knowledge, Attitudes and Practice of doctors in Uganda regarding screening, diagnosis and management of colorectal cancer.
REFNo: HS1198ES

To improve early detection, screening and the management of colorectal cancer in Uganda,
 Uganda 2021-03-15 2024-03-15 Medical and Health Sciences Non-degree Award
Amanda Murungi Eunice
ID:
Comparing the two transition feeding approaches in management of severe acute malnutrition among children 6-59 months: a randomized controlled trial (RCT)
REFNo: HS1200ES

To compare the effectiveness and outcomes of two transition phase feeding approaches (RUTF supplemented with F75 and RUTF only) children 6-59 months hospitalized with severe acute malnutrition in Mulago National Referral Hospital
 Uganda 2021-03-15 2024-03-15 Medical and Health Sciences Degree Award
Yahaya Gavamukulya
ID: UNCST-2019-R001017
 EVALUATION OF THE ANTI-SARS-CoV-2 ACTIVITY OF COMPOUNDS FROM Tephrosia linearis, Zanthoxylum chalybeum and Albizia coriaria AND FORMULATION OF HERBAL PRODUCT(S) FOR MANAGEMENT OF COVID-19
REFNo: HS1222ES

The general objective
To evaluate the antiviral potential of Tephrosia linearis, Zanthoxylum chalybeum and Alibizia coriaria, against SARS-CoV-2 and formulate herbal product(s) for management of COVID -19.

Specific objectives
i. To determine the in vitro anti-SARS‐CoV‐2 activity of the three selected medicinal plants in singular and in combination using SARS‐CoV‐2 infected mammalian cell lines (VeroE6).
ii. To determine the cytotoxicity and acute toxicity of the active medicinal plant(s) on mammalian cell lines (VeroE6) and swiss albino mice respectively.
iii. To determine the effects of the extracts on the immunological profile of cell lines
iv. To formulate and evaluate herbal product (s) from the most active medicinal plants for management of COVID-19.

Uganda 2021-03-15 2024-03-15 Medical and Health Sciences Non-degree Award
Kelly Mannion Ray
ID:
Understanding how variation in food effort and intake correlate with tool use in Bugoma Forest Chimpanzees
REFNo: NS155ES

To understand the potential drivers of tool use and how ecology plays a role
 USA 2021-03-15 2024-03-15 Natural Sciences Degree Award
Allen Kabagenyi
ID:
Adolescent Motherhood, Vulnerability Assessment and Newborn care practices, in Eastern Uganda (AMNEP)
REFNo: HS1248ES

The general objective of this study is to develop and test adolescent motherhood vulnerability assessment tool and to examine the knowledge, behavioral practices and perceptions of maternal and new born care among adolescent mothers in Luuka District.
Specific objectives
1. To examine the knowledge levels and awareness of maternal and newborn care among adolescent mothers and the community in Luuka District
2. To develop and test a community based adolescent mothers Vulnerability Assessment Tool
3. To assess the pre and postnatal maternal and newborn care practices and among adolescent mothers and the community in Luuka District
4. To explore the perceptions, vulnerability risk and barriers to unborn and newborn care management among adolescent mothers and the community in Luuka District

 Uganda 2021-03-15 2024-03-15 Medical and Health Sciences Degree Award
Sebastian Linnemayr
ID: UNCST-2021-R012696
 INcentives and ReMINDers to Improve Long-term Medication Adherence (INMIND)
REFNo: HS1286ES

We propose to test INMIND in a pilot, 3-arm randomized controlled trial (RCT) in Uganda with two intervention groups. All participants (including in the control group) will receive information about the importance of behavioral routines, as is part of the standard adherence counseling for treatment initiators, and create personalized ART adherence anchoring strategies. In the first intervention group, participants will additionally receive text messages to keep adherence and their anchoring strategy salient. In the second group, we add small incentives awarded conditionally on taking ART pills within a time window that corresponds to participants’ personalized anchoring strategy to increase the immediate rewards of adherence.

The Specific Aims
1.Develop the intervention using the ADAPT-ITT framework and evaluate the feasibility and acceptability of INMIND.
2: Test the preliminary effectiveness of the intervention, including the relative effectiveness of two different implementation approaches
3. Collect data in preparation for a subsequent R01 application
 USA 2021-03-15 2024-03-15 Medical and Health Sciences Non-degree Award
Dickens Akena Howard
ID: UNCST-2019-R000179
 The effect of psycho-education on clinical outcomes among patients with a first episode psychosis in central Uganda - A pilot randomized control trial
REFNo: HS1026ES

The study objectives are to (a) Conduct formative work and develop a manual for delivering psycho-education messages by Village Health Team (VHTs) members to individuals with first episode psychosis (FEP) and their families in central Uganda. (b) Examine the efficacy of psycho-education on symptom severity, stigma and retention in care. (c) Document feasibility and acceptability of implementing this intervention as well as barriers to its implementation
Uganda 2021-03-12 2024-03-12 Medical and Health Sciences Non-degree Award
JOSEPH Ngonzi
ID:
Quality Improvement Initiative in the Department of Obstetrics and Gynaecology
REFNo: HS967ES

1) To measure current health outcomes in the unit
2) To describe and analyze current process, behaviors, resources and availability
3) To develop and implement changes in current practices to improve outcomes while maximizing resources.
4) To monitor and evaluate health outcomes in the department of OB/GYN

 Uganda 2021-03-12 2024-03-12 Medical and Health Sciences Non-degree Award
Margaret Joanita Mutumba Nakalembe
ID:
Multi-level Analysis on Implementation of Low-Cost IVF in Sub-Saharan Africa: A Case Study of Uganda.
REFNo: HS1214ES

The objective of this study is to explore how LCIVF has been implemented in the public health system of Uganda. The more specific questions include; 1) How has LCIVF been operationalized at the micro-level within the clinical practice? 2) How has the public hospital at the meso-level organized itself to facilitate the implementation and provision of LCIVF? 3) How have macro-level factors influenced the implementation of LCIVF within the public health system? 4) How effective has the implementation of LCIVF been in addressing accessibility and affordability of infertility services in Uganda?
 Uganda 2021-03-12 2024-03-12 Medical and Health Sciences Degree Award
Nixon Niyonzima
ID: UNCST-2020-R014577
 MUTATIONAL PROFILE OF TRIPLE NEGATIVE BREAST CANCER IN WOMEN SEEKING CARE AT THE UGANDA CANCER INSTITUTE
REFNo: HS1264ES

1. To describe the mutational profile of triple negative breast cancer in women seeking care at the Uganda Cancer Institute
2. To describe the relationship between the mutational load and the primary tumor size of triple negative breast cancer in women seeking care at the Uganda Cancer Institute
3. To describe the differences in mutational profile by histological type in patients with triple negative breast cancer in women seeking care at the Uganda Cancer Institute

 Uganda 2021-03-12 2024-03-12 Medical and Health Sciences Degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
 An Evaluation of the Pediatric Care Process in Uganda for Improvement of Quality of Care
REFNo: HS1227ES

The primary objective of this study is to evaluate the typical pediatric care process at a representative sample of hospitals in Uganda
 Uganda 2021-03-11 2024-03-11 Medical and Health Sciences Non-degree Award
Peter Olupot-Olupot
ID:
Severe MAlaria A Research and Trials consortium: A protocol for a prospective case control observational study
REFNo: HS1231ES

To characterise the contemporary epidemiology (including features at presentation and the diagnostic and treatment pathway) of severe malaria presenting to hospital for admission in children in Africa, through conducting a prospective multicentre observational study across 7 sites in 6 countries, enrolling two cohorts of hospitalised children (i.e. stratified) with severe and non-severe malaria. For this study, severe malaria will be defined as children with a positive POC pHRPT2 test (Paracheck) meeting WHO criteria or Teule criteri. For severe malaria, we will characterise the proportions presenting with different severe complications, or combination of any of or all of these, and compare these proportions across sites. Secondary Objectives i. To compare baseline characteristics of admitted children with severe and non-severe malaria. ii. To document time from presentation to the hospital ‘gateway’ (e.g. outpatients or emergency/triage centre) to ward admission and time to first dose of parenteral artesunate to assess whether delays in initiating definitive antimalarial treatment could contribute to malaria severity. iii. To estimate the incidence of significant post-discharge events to day-180 including readmission (all-cause and for malaria (i.e. relapse)) and all-cause mortality in severe and non-severe malaria. iv. To develop (year 1) and evaluate (years 2 and 3) a point-of-care quantitative plasma Plasmodium falciparum histidine-rich protein2 (pfHRP2) test for estimating total body parasite burden, which could be used to swiftly identify those at greatest risk of poor outcomes.
Uganda 2021-03-11 2024-03-11 Medical and Health Sciences Non-degree Award
Tom Lutalo
ID:
Measuring adult health and mortality in Low- and Middle-Income Countries
REFNo: HS640ES

1. To evaluate the accuracy of survey data on adolescent and adult mortality collected retrospectively through siblings’ survival histories (SSH), compared to the reference mortality data collected prospectively.
2. To test whether the siblings of respondents can be reached and interviewed via mobile phone, in order to collect data on the risk factor of adult mortality

 Uganda 2021-03-10 2024-03-10 Medical and Health Sciences Non-degree Award
Levicatus Mugenyi
ID: UNCST-2020-R014759
 Understanding Factors Associated with IPT Completion among Recipients of Care on ART/IPT Aligned Multi-month Refills across the Differentiated Service Delivery Models
REFNo: HS1228ES

The primary objective is to understand factors associated with completion of IPT among clients in MoH’s integrated IPT/ART models.
Specific objectives:
1.To compare IPT completion rates amongst clients across the five DSD models: Facility-Based Individual Management (FBIM), Facility-Based Group (FBG), Fast Track Drug Refill (FTDR), Community Client Led ART Delivery (CDDP), and Community Drug Distribution Points (CCLAD).
2.To understand individual and facility level factors associated with IPT completion across the different DSD models
3.To compare IPT uptake across the different DSD models
4.To compare the frequency of adverse events (AEs) reported by clients on IPT across the different DSD models
5.To document patient and service provider KAP towards the IPT/ART integrated model

 Uganda 2021-03-10 2024-03-10 Medical and Health Sciences Non-degree Award
Pontiano Kaleebu
ID: UNCST-2021-R013577
 A Phase 1 Trial of ChAdOx1- and MVA-vectored Conserved Mosaic HIV-1 Vaccines in Healthy, Adult HIV-1-negative Volunteers in Eastern and Southern Africa
REFNo: HS844ES

Safety
ï‚· To evaluate the safety and tolerability of a prime boost vaccine regimen utilizing non-replicating simian adenovirus (ChAdOx1) followed by non-replicating poxvirus modified vaccinia virus Ankara (MVA) in adults in Eastern and Southern Africa
Immunogenicity
ï‚· To evaluate the specific T-cell immune responses induced by the ChAdOx1.tHIVconsv1 followed by MVA.tHIVconsv3&4 vaccines in vaccine recipients.
SECONDARY
ï‚· To assess tHIVconsvX-specific T-cell responses of for their frequency, breadth and duration in vaccine recipients.
ï‚· To assess functional T-cell responses in vaccine recipients that inhibit replication in vitro of viruses of major HIV-1 clades A, B, C and D.
EXPLORATORY
ï‚· To assess induction of plurifunctional tHIVconsvX-specific memory T cells in the vaccine recipients.
ï‚· Characterization of the gut microbiome composition and richness.
 Uganda 2021-03-05 2024-03-05 Medical and Health Sciences Non-degree Award
Esther Buregyeya
ID: UNCST-2020-R014116
 USING SHORT MESSAGE SERVICE REMINDERS AND MOBILE MONEY INCENTIVES TO ENHANCE LINKAGE TO CARE OF PRESUMPTIVE TUBERCULOSIS PATIENTS IN UGANDA: A RANDOMISED CONTROLLED TRIAL
REFNo: HS993ES

To evaluate the TB diagnostic process and linkage to care by doing cohort analysis.

2. Develop and adapt an SMS reminders and MM incentives to improve linkage to care among TB patients.

3. Conduct a randomized controlled trial of SMS reminders and MM incentives sent to presumptive and confirmed TB patients to improve linkage to care and treatment.

4. To build sustainable capacity in TB research clinical trials in Uganda.

Uganda 2021-03-05 2024-03-05 Medical and Health Sciences Non-degree Award
Jude Onyango Tadeo
ID:
FAMILY SUPPORT, DIABETES SELF-MANAGEMENT, AND GLYCEMIC CONTROL AMONG PATIENTS ATTENDING DIABETIC CLINICS OF REGIONAL REFERRAL HOSPITALS IN EASTERN UGANDA (FS-DSM-GC STUDY)
REFNo: HS1040ES

Research Study objectives:
General objective:
To examine the association between perceived family support, diabetes self-management behavior and glycemic control among patients attending Regional Referral hospitals in the eastern region of Uganda.
Specific objectives:
1. To determine the association between perceived family support and diabetes self-management behavior among patients attending outpatient clinics of Regional Referral Hospitals in the eastern region of Uganda.
2. To determine association between perceived family support and glycemic control among patients attending outpatient clinics of Regional Referral Hospitals in the eastern region of Uganda.

 Uganda 2021-03-05 2024-03-05 Medical and Health Sciences Non-degree Award
Jonathan Mayito
ID:
Utility of the monocyte to lymphocyte ratio in diagnosing latent tuberculosis among HIV-infected individuals with a negative tuberculosis symptom screen.
REFNo: HS1066ES

1. To determine the diagnostic performance of the monocyte to lymphocyte ratio against IGRA in diagnosing latent TB among HIV-infected individuals with a negative tuberculosis symptom screen.
2. To determine the change in the monocytes to lymphocytes ratio measured at baseline, and three months among HIV-infected individuals during tuberculosis preventive therapy.

 Uganda 2021-03-05 2024-03-05 Medical and Health Sciences Non-degree Award
Namulema Edith
ID:
Evaluation of the Safety and Tolerability of the ‘LeVe CPAP Flow Generator’ in Healthy Volunteers at Mengo Hospital in Kampala Uganda
REFNo: HS1250ES

To determine the safety, tolerability and acceptability of the LeVe CPAP Flow Generator’ among healthy volunteers at Mengo Hospital and to ensure they do not cause harm.
 Uganda 2021-03-05 2024-03-05 Medical and Health Sciences Non-degree Award
Patrice Mawa Akusa
ID:
Establishing a pool of school-going adolescent girls and boys as immunisation ambassadors in Entebbe, Uganda
REFNo: HS1215ES

Overall rationale One way of engaging and empowering mothers and communities and linking them to immunisation services is by use of their own daughters and sons. The relationship between mother and her daughter is full of learning experiences and one of the strongest bonds. Mothers also have emotional relationship with their sons and will likely listen to them. Objectives The objective of the project is to establish a pool of school-going adolescent girls and boys as‘immunisation ambassadors’ and change agents able to engage and empower mothers and community members and link them to maternal and neonatal immunisation services by training them on vaccines and leadership skills.
Uganda 2021-03-03 2024-03-03 Medical and Health Sciences Non-degree Award
Sylvia Nabukenya
ID: UNCST-2019-R000906
 UNDERSTANDING STAKEHOLDER PERSPECTIVES, PREFERENCES AND EXPERIENCES FOR THE RETURN OF PHARMACOGENOMICS RESEARCH RESULTS AMONG PEOPLE LIVING WITH HIV AIDS.
REFNo: SS735ES

GENERAL OBJECTIVE

To explore stakeholder perspectives, preferences and experiences in contribution to development of locally contextualized institutional guidelines for returning individual pharmacogenomics research results to people living with HIV.

SPECIFIC OBJECTIVES

1. To explore stakeholders’ attitudes, perspectives and experiences towards the return of individual pharmacogenomics research results among people living with HIV.

2. To determine factors that influence decisional preferences for receiving individual pharmacogenomics research results among people living with HIV

3. To develop institutional guidelines for the return of individual pharmacogenomics research results to research participants.

 Uganda 2021-03-03 2024-03-03 Social Science and Humanities Degree Award
Patrice Mawa Akusa
ID:
Exploring immune responses in primary and more advanced Schistosoma mansoni infection and treatment of preschool-age children using Aurora spectral flow cytometry
REFNo: HS1223ES

Objective 1: To characterize immune responses of PSAC in primary and more advanced S. mansoni infection

Objective 2: To determine the effect of PZQ treatment of S. mansoni on immune responses in PSAC.

 Uganda 2021-03-03 2024-03-03 Medical and Health Sciences Non-degree Award
LYDIA NAKIGANDA JACENTA
ID:
Demographic characteristics, attitudes, behaviours and sexually transmitted infections among female sex workers using HIV Pre- Exposure Prophylaxis living in the fishing communities around Lake Victoria Basin, Uganda.
REFNo: HS813ES

i.To define demographic characteristics
ii.To explore sexual behaviours, in association with PrEP prescription,
iii. To explore self-reported adherence rates and correlates of adherence
iv. To examine the STI disease burden, use of condoms and explore associations between condom use and STIs.
v. To explore factors that might facilitate or challenge PrEP use, such as side effects and stigma, and
vi. To understand FSWs’ experiences, perceptions of & attitudes towards PrEP

Uganda 2021-03-01 2024-03-01 Medical and Health Sciences Degree Award
Jaffer Okiring
ID:
Increasing malaria trends amidst routine core interventions among residents of varying transmission settings of Uganda
REFNo: HS1033ES

1) To compare the malaria trends measured using Test Positivity Rate and Total laboratory confirmed cases of malaria relative to incidence in high malaria settings in Uganda
2) To determine household level factors associated with malaria incidence at 68 sites with varying malaria transmission intensity.
3) To investigate the environmental factors associated with malaria incidence and how these factors modify the impact of core vector control interventions in Uganda
4) To develop a model that can predict malaria incidence in different epidemiological settings and how the incidence will vary with the roll out of different core interventions in Uganda.

 Uganda 2021-03-01 2024-03-01 Medical and Health Sciences Degree Award
Elizeus Rutebemberwa
ID: UNCST-2022-R009070
 Evaluation and Scale-up Strategy for the Doctor@Distance Programme in Uganda
REFNo: HS955ES

4.3 General objective
To evaluate the Doctor@Distance programme by identifying current benefits and gaps and exploring the path for further development of the programme and potential embedment of the programme in the larger health system.

4.4 Specific objectives
1.To explore what the multi-stakeholder perceptions are on the design and daily practice of the Doctor@Distance programme
2.To analyse the design and current utilisation of the Doctor@Distance programme and identify potential gaps in its coverage (how often is it used, by whom, for which diseases, etc.)
3.To evaluate the current healthcare gaps in the communities in which the community health entrepreneurs of the Doctor@Distance programme are active
4.To explore how the Doctor@Distance programme can be scaled-up to other districts within Uganda
5.To investigate multi-stakeholder perceptions on the possibility of integration of the Doctor@Distance programme in the larger health system in Uganda


 Uganda 2021-03-01 2024-03-01 Medical and Health Sciences Non-degree Award
Richard Nyeko
ID: UNCST-2021-R012815
 Pre-hospital exposure to, and antimicrobial drug resistance patterns among febrile children presenting to St. Mary’s Hospital Lacor, northern Uganda
REFNo: HS1091ES

General objective To determine the prevalence of pre-hospital exposures to antibiotics, common bacteria and their susceptibility to microbial drugs among febrile children presenting to a tertiary health facility in northern Uganda. Specific objectives 1. To determine the prevalence of pre-hospital exposures to antibiotics among febrile children presenting at St Mary’s Hospital Lacor 2. To establish the common bacterial isolates among febrile children presenting at St Mary’s Hospital Lacor 3. To determine the microbial resistance patterns among febrile children presenting at St Mary’s Hospital Lacor
Uganda 2021-03-01 2024-03-01 Medical and Health Sciences Non-degree Award
Aidah Nanvuma
ID: UNCST-2024-R015734
 EVALUATING THE CAPACITY BUILDING MODEL USED TO NURTURE INDEPENDENT RESEARCH INVESTIGATORS AT THE INFECTIOUS DISEASES INSTITUTE, UGANDA
REFNo: HS1100ES

Objective 1: To describe Capacity Building Unit support activities and scholarly outputs and outcomes since inception. Objective 2: To determine how particular components of the unit scientific and non-scientific support(Inputs) contribute to scholar (past and present) outputs and outcomes since inception. Objective 3: To identify and address areas of improvement in unit support activities through the engagement of current and former stakeholders (beneficiaries and benefactors).
Uganda 2021-03-01 2024-03-01 Medical and Health Sciences Non-degree Award
Moses Joloba Lutaakome
ID: UNCST-2022-R011558
 A Study to Validate and Improve an Automated Image Analysis Algorithm to Detect Tuberculosis in Sputum Smear Slides: Version 1.0 dated Nov 2020
REFNo: HS1144ES

1. Validate the platform, and assess efficiency improvements from computerized detection approaches.
a. Perform a slide specimen digitization (400 slides, 98 images/slide, 39,200 images).
b. Classify all images as dark/medium/light based on color histogram data.
c. Assess accuracy vs. manual microscopy, and sensitivity/specificity vs. bacterial culture.
d. Develop a new image analysis algorithm by integrating software applications that include Artificial Intelligence (AI) approaches via Convolutional Neural Networks (CNN).
2. Quantify slide staining quality and variability through the use of novel methods which exploit the color spectra of stained slides.
a. Determine factors which led to poor slide preparation.
b. Test a new quality control method (HistoQC) to standardize clinical slide preparations

 Uganda 2021-03-01 2024-03-01 Medical and Health Sciences Non-degree Award
THOMSON LAKWO LURONI
ID: UNCST-2023-R007843
 Evaluation of the Diagnostic Tests in Areas Hypoendemic for Onchocerciasis –Uganda: a follow-up study.
REFNo: HS1220ES

Objective 1: Evaluate the distribution of anti-OV-16 antibody and other markers of O. volvulus infection in multiple age groups over time in an area of active intervention for onchocerciasis
Objective 2: To determine whether a serologic threshold of 2% that modeling suggested is consistent with interruption of transmission.
Objective 3: Monitor for sero-reversion of OV-16 antibody positivity in a nested cohort of individuals who participated in the previous study.

 Uganda 2021-03-01 2024-03-01 Medical and Health Sciences Non-degree Award
Moses Joloba Lutaakome
ID: UNCST-2022-R011558
 Predicting the Future: Incipient Tuberculosis (PreFIT)
REFNo: HS1242ES

1.1 Aim:
To validate the clinical performance, cost, and feasibility of a package of ready-to-use new and existing candidate diagnostic assays for the prediction of the development of active TB.
1.2 Objectives:
1. Establish a multi-country diagnostic evaluation cohort of highly exposed TB contacts free of co-prevalent active TB, followed prospectively for active TB development over a 12-months period, and collect and store biological specimens from these contacts at pre-set time-points for laboratory testing; and
2. Validate a package of candidate assays for their predictive accuracy (sensitivity, specificity, positive and negative predictive values) for incident TB, feasibility, and cost. Based on combining results for the different tests, cost-optimised predictive algorithms will be derived.

 Uganda 2021-03-01 2024-03-01 Medical and Health Sciences Non-degree Award
Miriam Nansunga
ID:
ASSESSMENT OF THE SAFETY AND EFFICACY OF COMMON MEDICINAL PLANTS OF CENTRAL UGANDA ON IMPAIRED LEARNING AND MEMORY IN RATS
REFNo: HS648ES

1. To identify medicinal plants of Central Uganda used in the management of memory impairment.
2. To determine the effect of the aqueous extracts of the 5 most commonly mentioned plants on escape latency in the Morris Water Maze and step down latency in Passive Avoidance test.
3. To determine the effect of the total crude extracts of the two most effective plants on: acetylcholine, glutamate; muscarinic receptor M1, M3 and M5; glutamate receptors AMPA and NMDA in the hippocampus and orbital frontal cortex

4. To establish the safety and toxicity profile of the two most active plants extracts on memory and learning enhancement.

 Uganda 2021-02-26 2024-02-26 Medical and Health Sciences Degree Award
Leevan Tibaijuka
ID: UNCST-2021-R012986
 Predictors for preterm neonatal mortality at Mbarara Regional Referral Hospital
REFNo: HS469ES

General objective
To Describe the Predictors for Preterm Neonatal Mortality among preterm babies delivered at Mbarara Regional Referral Hospital (MRRH).
Specific objectives
1. To describe the neonatal mortality of preterm babies at Mbarara Regional Referral Hospital
2. To describe the association of antenatal care attendance, antenatal corticosteroid use and mode of delivery with preterm neonatal death at Mbarara Regional Referral Hospital

 Uganda 2021-02-25 2024-02-25 Medical and Health Sciences Degree Award
Francis Ekadu
ID:
Uganda Bribery Index
REFNo: SS392ES

To increase citizens awareness on the prevalence, gravity and impact of corruption in uganda
 Uganda 2021-02-25 2024-02-25 Social Science and Humanities Non-degree Award
Lucrèce Ahovègbé Yémalin Judith
ID:
Evaluation of two medicinal plants on key factors causing treatment failure in Hepatitis C infection
REFNo: HS1004ES

1. Evaluate the antiviral and anti-mutagenic effect of A. nilotica and T. ciliata on HCV in presence and absence of DAA
2. Evaluate the effect of A. nilotica and T. ciliata on induced mutation in HCV infection in presence and absence of DAA
3. Determine effect of A. nilotica and T. ciliata on immunologic parameters involved in body response to HCV in presence and absence of DAA
4. Investigate the genotypes of HCV circulating in African region (Uganda, Benin) and their response in vitro to DAAs

 Benin 2021-02-25 2024-02-25 Medical and Health Sciences Degree Award
PAUL KATO KALYEBARA KALYEBARA
ID:
INCIDENCES OF RE-MARRIAGE, LIVE CHILDBIRTH AND RECURRENCE OF INCONTINENCE AMONG WOMEN THAT UNDERWENT OBSTETRIC FISTULA REPAIR AT MBARARA REGIONAL REFERRAL HOSPITAL FROM 2010 TO 2019
REFNo: HS1060ES

General objective
To determine the incidences of re-marriage, live childbirth and recurrence of incontinence among women who had successful obstetric fistula repair at Mbarara Regional Referral Hospital from 2009 to 2019.
Specific objectives
1. To determine the incidence of re-marriage among women who had successful fistula repair at Mbarara Regional Referral Hospital from 2010 to 2019.
2. To determine the incidence of live childbirth among women who had successful obstetric fistula repair at Mbarara Regional Referral Hospital from 2010 to 2019.
3. To compare recurrence rates of incontinence after childbirth occurring among women who had successful genitourinary and rectovaginal fistula repair at MRRH from 2010 to 2019.

 Uganda 2021-02-25 2024-02-25 Medical and Health Sciences Degree Award
FREDDIE SSENGOOBA Peter
ID: UNCST-2021-R011834
 Political Economy Analysis of sub-national health management in Eastern and Southern Africa
REFNo: SS664ES

This study will explore the dynamics taking place at sub-national level (e.g. within counties or districts) as well as between national and sub-national levels along the following objectives:
1. Analyze the environment for decision-making and implementation of health plans at sub-national level, including existing formal and informal processes for decision-making; political, financial, social, and other influences on sub-national prioritization, decision-making and resource allocation, including relevant changes over time (e.g. post-devolution), and how data and evidence play a role.
2. Identify and characterize key stakeholders with a role in sub-national health management and systems—key characteristics will include technical capacity, their use of data and evidence, the relationships and power dynamics between them, and the existing structures for engagements with non-health sector authorities, both formal and informal.
3. Assess existing formal and informal accountability mechanisms for sub-national decision-making for health (both within the health system and for external stakeholders like beneficiary communities, sub-national decision-makers (county/district), and development partners) with a view to identify ways to improve the relative effectiveness of accountability mechanisms in decision processes.
4. Analyze social sector spending trends and beneficiaries, their relation to health sector policies, and how local governance structures influence them, where available.
5. Develop draft plan for piloting strategies to address challenges identified by the PEA, including proposed implementation and monitoring and evaluation approaches, as appropriate.
6. Analyze the policy environment on community health, including key stakeholders, to identify potential approaches for integrating a new community health extension worker program into existing systems, especially at district level
7. Analyze the current digital health innovations governance and accountability structures, (including key stakeholders across sectors and how their responsibilities and priorities overlap,) to identify strategies for strengthening existing structures, enhancing accountability and minimizing duplication

Uganda 2021-02-25 2024-02-25 Social Science and Humanities Non-degree Award
Silvia Kahihu Wairimu
ID:
Improving the Impact of VSLAs on Refugees’ and Host Communities’ Self- reliance, Resilience and Economic Capacity
REFNo: SS658ES

Our main objective is to investigate different facets of the VSLA (structure, benefits, and barriers as well as future opportunities) with the aim of optimizing its design. This is because we hypothesize that optimizing the structure of the VSLA will lead to increased financial inclusion of the group members as well as social capital.
 Kenya 2021-02-25 2024-02-25 Social Science and Humanities Non-degree Award
Dianah Ahumuza Ateenyi
ID:
The impact of tax incentives on the realisation of economic and social rights: A focus on tax holidays and the right to basic education in Uganda
REFNo: SS666ES

1. To examine the historical background and justification of tax incentives generally and tax holidays specifically especially in Uganda.
2. To explore the adequacy of the legal and policy framework on tax incentives, especially tax holidays in Uganda and how it impacts revenue for the realisation of ESRs, specifically the right to basic education;
3. To analyse the relationship between government revenue and basic education financing and how it the realisation of the right to basic education.
4. To recommend appropriate legal, policy and administrative reforms for the better management of tax incentives generally and tax holidays specifically for the realisation of Uganda’s international and domestic ESRs obligations, with specific emphasis on the right to basic education.

 Uganda 2021-02-25 2024-02-25 Social Science and Humanities Degree Award
Joseph Lutaakome
ID: UNCST-2020-R008323
 An International Observational Study to Characterize Adults Who Are Hospitalized with Influenza or Other Targeted Respiratory Viruses (INSIGHT Protocol No. 003 version 3.0, dated 27 August 2013); Flu003 PLUS AND Genomic Study: INSIGHT Protocol No. 004 version 2.0, dated 27 August 2013 -A substudy of qualifying INSIGHT studies
REFNo: HS1108ES

The objectives of this study for participants with confirmed influenza are to:

1. Characterize individuals who are hospitalized with influenza in terms of demographics, co-morbid conditions, prior influenza vaccination (seasonal, including 2009 H1N1) and pneumococcal vaccination, and use of antivirals, overall and according to influenza type, A or B, and influenza A subtype.

2. Estimate the percent who die and who develop a composite outcome, overall and according to the identified influenza type or subtype: death, a requirement for mechanical ventilation or admission to the intensive care unit (ICU), or prolonged hospitalization following enrollment (duration of hospitalization >28 days) at 60 days after enrollment.

3. Study risk factors, (e.g., patient and viral characteristics, geographic location, influenza type and subtype) for mortality and the composite outcome of death, a requirement for mechanical ventilation or admission to the ICU, or prolonged hospitalization following enrollment (duration of hospitalization >28 days).

4. Establish a repository of oropharyngeal, nasal and lower airway samples to determine a laboratory diagnosis; to molecularly characterize the virus, including subtype, antigenic and genetic analyses; to identify known signature mutations for antiviral drug resistance, mutational evolution, and additional re-assortment; and assess possible co-pathogens.

5. In a subset of patients requiring mechanical ventilation, to collect paired upper and lower airway samples to molecularly characterize the virus according to anatomic location, assess the potential emergence of antiviral resistance and assess possible co-pathogens.

6. Establish a repository of serum and plasma for future studies, including measurement of biomarkers that predict disease severity and measures of host response to infection with influenza virus.

7. Compare the characteristics and outcomes of patients infected with different influenza virus types and subtypes, including 2009 H1N1 virus, over time and by geographic region.

8. Identify and characterize other viral and bacterial pathogens, including coinfections.

The objectives of this study for participants with targeted non-influenza viral respiratory infections are to:

1. At enrollment, characterize individuals who are hospitalized with a targeted viral respiratory disease in terms of possible source of infection and mode of transmission, demographics and co-morbid conditions.

2. At 28 and 60 days of follow-up, estimate the percent who die, require admission to the ICU, have prolonged hospitalization, or recover.

3. Establish a repository of prospectively collected serum, plasma and respiratory tract specimens for future studies, including measurement of biomarkers that predict disease severity and measures of host immune response to infection.

 Uganda 2021-02-25 2024-02-25 Medical and Health Sciences Non-degree Award
Jane Frances Namatovu
ID: UNCST-2020-R014353
 CONTINUING PROFESSIONAL DEVELOPMENT FOR PRIMARY CARE DOCTORS IN LOW RESOURCE SETTINGS: DEVELOPING A COMPETENCY-BASED FRAMEWORK
REFNo: HS1170ES

1.To determine the CPD training needs of primary care doctors working in public general hospitals (GHs) and health center IVs (HC IVs) of central Uganda
2.To explore the perceived barriers to and facilitators of CPD among primary care doctors working in public GHs and HC IVs of central Uganda
3.To explore the views of key stakeholders on CPD for doctors working in public GHs and HC IVs of central Uganda
4.To develop a competency-based CPD framework for primary care doctors working in public GHs and HC IVs of central Uganda
 Uganda 2021-02-25 2024-02-25 Medical and Health Sciences Degree Award
Dennis Muhanguzi
ID: UNCST-2019-R001101
 Targeting Domestic Animals and Tsetse Fly Vectors to Control Nagana and Accelerate Elimination of Acute Sleeping Sickness from Hot Spot Villages of Eastern Uganda
REFNo: A107ES

The main objective of this study will be to determine whether targeting hotspot villages would accelerate elimination of rHAT The specific objectives of this project will be to determine; i. If rHAT hotspot village-based interventions [two doses of diminazene aceturate 40 days apart at the beginning of the intervention and monthly RAP] will progressively reduce T. brucei s.l. reservoir in cattle and hence insidious rHAT transmission. ii. The drivers of insidious rHAT transmission in hotspot rHAT hotspot villages in Dokolo and Kaberamaido districts.
Uganda 2021-02-25 2024-02-25 Agricultural Sciences Non-degree Award
NOLBERT GUMISIRIZA KAGAMBIRWE
ID:
Investigating how the specialized and decentralized treatment healthcare models for all forms of epilepsy in Uganda fared in the covid-19 pandemic
REFNo: HS1156ES

1. To assess the government strategy of decentralized care and treatment for persons with all forms of epilepsy in Uganda, before COVID-19.

2. To assess the effects of the COVID-19 pandemic on access to epilepsy care in Uganda

3. To assess the socio-economic and mental health effects of the COVID-19 pandemic on persons with epilepsy in Uganda.

4. To generate ideas and strategies to improve the existing models for epilepsy care in Uganda∙

Uganda 2021-02-25 2024-02-25 Medical and Health Sciences Degree Award
Bjorn Van Campenhout -
ID: UNCST-2020-R014080
 Impact of Covid-19 on maize and dairy value chains in Uganda
REFNo: SS699ES

Specific objective: To assess the impact of Covid-19 on the maize and dairy value chain in Uganda. Specific objective: to determine how the COVID-19 pandemic affected production, marketing/sales and welfare of actors/households along the two value chains.
 Belgium 2021-02-25 2024-02-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
Godfrey Ejuu
ID: UNCST-2021-R013978
 Effectiveness of Inclusive Home-based Early Learning Model in Increasing Access to Early Child Education (ECE) for Children in Marginalised Communities
REFNo: SS740ES

1. To describe contextually relevant pedagogical practices that result into better child school readiness outcomes in home based ECCE centres
2. To compare the impact of the play- based ECCE curriculum model program on children’s school readiness relative to the control group
3. To determine the impact of pedagogical mentorship program on teacher professional well-being, classroom quality, and children’s school readiness relative to a control group

 Uganda 2021-02-25 2024-02-25 Social Science and Humanities Non-degree Award
Eddy Walakira Joshua
ID: UNCST-2022-R009077
 SITUATION ANALYSIS OF THE IMPACT OF COVID - 19 ON GLOBAL FUND TO END MODERN SLAVERY’S SUPPORTED PROGRAMMES TO END COMMERCIAL SEX EXPLOITATION OF CHILDREN AND ENDING LABOUR EXPLOITATION
REFNo: SS757ES

This is a program evaluation study focusing on CSEC and OLR programs. As a result, the primary questions are divided into two corresponding to the two study sub-components.

Broadly, this study seeks to establish the likely impact of COVID 19 on the implementation of the Commercial and Sex Exploitation programmes supported by the Global Fund to End Modern Slavery, in Kampala and Karamoja areas.
Uganda 2021-02-25 2024-02-25 Social Science and Humanities Non-degree Award
Samwel Wangombe
ID:
INTERNAL CONTROLS, REGULATORY MECHANISMS AND FINANCIAL ACCOUNTABILITY IN INDIGENOUS NON-PROFIT ORGANISATIONS IN UGANDA
REFNo: SS734ES

1. Describe the accounting internal controls applicable to indigenous non-profit organisations.
2. Determine the significance of accounting internal controls on the level of compliance with legal and/or regulatory requirements.
3. Determine the significance of accounting internal controls on the choice of self-regulatory mechanism.
4. Evaluate the extent to which resource dependence theory determines the quality and consistency of financial reporting.
5. Explain the relationship between internal controls, regulatory mechanisms and financial accountability.
Kenya 2021-02-24 2024-02-24 Social Science and Humanities Degree Award
Murungi Elizabeth Mwebesa
ID:
Creating an Ecosystem exemplifying Cross Sector Cooperation Approach towards road safety of motorcycles in Kampala, Uganda
REFNo: SIR43ES

Each safe riding behavior belongs to either Priority (P), Speed (S) or Comprehension (C). So it is imperative to understand which factors affect which behavior and the extent of this effect.Therefore the objectives of this study are;
a)To identify the PPM (Push, Pull, Mooring) factors that promote each of the safe riding behaviors (PSC component).

b)To understand the extent to which push, pull and mooring factors influence the behavior of riders that have had contact with these parameters and those that haven’t.

c)To create a Theory of Change (ToC) model to propose the possible road map to changing the behaviors of riders. Leveraging on these two results above, a proposal of the possible road map to changing the behavior of riders will be made by creating a Theory of Change (ToC) table

 Uganda 2021-02-24 2024-02-24 Engineering and Technology Degree Award
Goretty Nagawa Mary
ID:
Implications of Land Use and Land Cover Changes towards Household Food Security in the Forested and Grassland areas of Mount Elgon Slopes
REFNo: NS122ES

Overall aim of the study
The study seeks to analyze land use and cover changes; and to establish the contribution of this towards carbon emission levels, and climate variations; and to assess the implication towards household food security by looking at the quality, diversity and quantity acquisition procedures within the households of Mount Elgon slopes.
1.3.2 Specific objectives
1. To analyse land use and cover changes on Mt Elgon slopes and assess their impact on CO2 effluxes from the soil in forest and grass land cover/use types.
2. To assess climate variability in relation to land use and land cover changes; and CO2 effluxes in the forested and grassland areas of Mt Elgon Slopes.

3. To assess the impact of land use and cover changes on household food security on Mount Elgon slopes.

 Uganda 2021-02-24 2024-02-24 Natural Sciences Degree Award
Emanuele Colonnelli
ID:
Do Corruption Perceptions Kill Competition?
REFNo: SS654ES

Increasing competition in public procurement is a key priority in many developing countries. High and widespread participation in the public procurement market is crucial to ensure the proper functioning of the procurement system, and ultimately high quality public investment. Public procurement of goods and services represents the primary area of government investment, accounting for 14.5% of GDP in low-income countries.
In this study, which takes place in Uganda, we aim to study the role played by a key potential barrier to competition in the public procurement market: firms' perception of public procurement as a rigged system, driven by bureaucratic corruption and personal connections. If these perceptions are widespread among market participants, governments may find it challenging to increase competition for public procurement. Furthermore, if perceptions spillover across public bodies, perceptions of systemic corruption may negatively affect competition even in those public bodies which manage to achieve high performance standards. This may in turn hinder bureaucrats' incentive to increase the performance of their organization, since efforts to reform a public body may not directly map into better perceptions of it among the public.
 Italy 2021-02-24 2024-02-24 Social Science and Humanities Non-degree Award
Cissy  Kityo
ID: UNCST-2021-R013663
 A Phase 3b, Randomized, Multicentre, Open-Label Study Evaluating the Efficacy, Safety, and Tolerability of Switching to Long-Acting Cabotegravir Plus Long-Acting Rilpivirine From Current Antiretroviral Regimen in HIV-1 Infected, Virological Suppressed Adults in Sub-Saharan Africa. (Cabotegravir And Rilpivirine: Efficacy and Safety Study: The CARES Study)
REFNo: HS1117ES

1.To demonstrate the non-inferior antiviral
activity of switching to IM RPV LA+CAB
LA administered every 2 months compared
with continuation of cART administered
daily over 12 months in HIV-1 infected
participants in a resource limited setting.
2.To demonstrate the antiviral and
immunologic activity of switching to IM
RPV LA+CAB LA every 2 months
compared to continuation of cART over 12
and 24 months of follow-up
3.To evaluate the safety and tolerability of
switching to RPV LA+CAB LA every 2
months compared to continuation of cART.
4.To assess viral resistance in participants
experiencing protocol-defined confirmed
virologic failure (plasma HIV-1 RNA ≥200
c/mL).
5.To assess the incidence of on-treatment
genotypic resistance to CAB, RPV and
other on-study cART up to Month 12 and
24.
 Uganda 2021-02-24 2024-02-24 Medical and Health Sciences Non-degree Award
Joaniter Nankabirwa Immaculate
ID: UNCST-2021-R012896
 Evaluation of the household-level impact of a single round of intermittent preventive treatment of malaria in schoolchildren: A randomized study
REFNo: HS1123ES

1. To determine the impact of intermittent preventive treatment of malaria in schoolchildren on malaria transmission at the household, as measured by the prevalence of parasitaemia at the household level.
2.To determine the impact of intermittent preventive treatment of malaria in schoolchildren on the health of the children as measured by the prevalence of parasitaemia among the children.

Uganda 2021-02-24 2024-02-24 Medical and Health Sciences Non-degree Award
Cathy Green Louise
ID:
An Investigation into the Impact on Social Inclusion of High Volume Transport (HVT) Corridors and Potential Solutions to Identifying and Preventing Human Trafficking
REFNo: SS704ES

1. To investigate the role played by HVT corridors in human trafficking in Uganda and Tanzania;
2. To explore some of the factors (primarily transport-related and regulatory) that are contributing to human trafficking along HVT corridors (roads);
3. To assess the level of awareness of human trafficking and its impacts among transport providers, the users of HVT corridors, and the communities through which these routes pass;
4. To identify and recommend pilot innovations that can help recognise and counter human trafficking along HVT corridors.

 UK 2021-02-24 2024-02-24 Social Science and Humanities Non-degree Award
Beatrice Achan
ID:
Epidemiology of Invasive Fungal Diseases in Uganda
REFNo: HS1127ES

1. Estimate the prevalence of fungemia due to Candida, Cryptococcus and Aspergillus species.
2. Describe the host and environmental factors associated with fungemia.
3. Determine the antifungal resistance profiles of the isolated fungal pathogens.
4. Determine the molecular ecology of Cryptococcus species causing cryptococcal meningitis.
5. Estimate the prevalence of mycetoma in Uganda.

 Uganda 2021-02-24 2024-02-24 Medical and Health Sciences Non-degree Award
Noble Banadda
ID:
Unlocking resilience benefits from African water resources (RESBEN)
REFNo: A112ES

1. To establish and develop the ARUA Water CoE as an effective, high performance, research hub & nodes network of African researchers & post graduate students
2.To establish a common intellectual grounding and poastgraduate supervision capabilities in complex social ecological systems and transdisciplinarity
3. To recognise the primary and secondary research strength
4. To locate the primary and secondary research strengths in relation to the SDGs
 Uganda 2021-02-24 2024-02-24 Agricultural Sciences Non-degree Award
Christine  Wiltshire Sekaggya
ID: UNCST-2019-R000578
 A phase II trial to describe the pharmacokinetics, safety and efficacy of pharmacogenetics-guided dosing of isoniazid in patients with HIV-associated TB
REFNo: HS1159ES

• To describe the pharmacokinetics of isoniazid, given at a higher dose (10mg/kg) among patients with fast or intermediate NAT2 acetylator status and a standard dose (5mg/kg) among patients with slow NAT2 acetylator status, among patients with HIV and drug sensitive TB.
• To investigate the safety of pharmacogenetically-determined isoniazid dosing among TB-HIV co-infected patients with drug sensitive TB.
• To explore the efficacy of isoniazid among TB-HIV co-infected patients with drug sensitive TB receiving pharmacogenetically-determined dosing, using pharmacokinetic – pharmacodynamic (PK-PD) models.

Uganda 2021-02-24 2024-02-24 Medical and Health Sciences Non-degree Award
Olive Kobusingye Chifefe
ID:
Observational Studies on Helmet Use, Speeding, Seat-Belt and Child Restraint in Kampala, Uganda
REFNo: HS1178ES

Main objective:
To establish the prevalence of road traffic crash severity risk factors in Kampala city namely speed, use of helmet use, seat-belt use, and drink- driving to generate evidence that can be used to inform policy and implementation strategies to promote road safety.

Specific objectives:
1. To assess the prevalence of seat-belt use and child restraint use among car occupants in Kampala.
2. To determine the prevalence of helmet use among motorcyclists in Kampala
3. To establish the prevalence and extent of speeding in Kampala
4. To determine the level of drink-driving in Kampala


Uganda 2021-02-24 2024-02-24 Medical and Health Sciences Non-degree Award
Karugahe Wilber
ID:
Identifying psychosocial impact of COVID-19 and promising practices for meeting the mental health and protection needs to SGBV of vulnerable populations during a protracted crisis in Kampala Slums
REFNo: SS721ES

1. Identification of psychosocial and mental health issues/problems for potential SGBV victims as a result of COVID-19 pandemic.
2. To examine the relationship that exists between psychosocial and mental health issues, Sexual Gender based violence and Coping strategies among potential SGBV victims.
3. Identify the coping strategies to help potential SGBV victims to improve their mental health, avoid prevent its occurrence or re-occurrence.

 Uganda 2021-02-24 2024-02-24 Social Science and Humanities Non-degree Award
Mohammed Lamorde
ID: UNCST-2019-R001293
 COVID-19 in people living with HIV: Evaluation of risk factors and outcomes in resource-limited settings
REFNo: HS1192ES

To characterize the clinical features and course of symptomatic COVID-19 in PLWH, described overall and by HIV and comorbid disease factors including pregnancy status
 Nigeria 2021-02-24 2024-02-24 Medical and Health Sciences Non-degree Award
Dorothy  Nalweyiso Irene
ID:
Enhancing Ugandan undergraduate healthcare students’ application of evidence into practice through the development and evaluation of an Evidence-Based Practice Education Package
REFNo: HS1246ES

The main objective of the study is to determine the impact of an Evidence Based Practice (EBP) educational Package on the knowledge, skills, attitudes and behavior among undergraduate healthcare students in Uganda.
Specific objectives of the study:
i) To assess of the current literature regarding the present approaches for teaching EBP among undergraduate healthcare students.
ii) To explore the views and experiences of lecturers regarding the training and use of EBP in health practice.
iii) To assess the perceived knowledge, skills, attitudes and behaviour of EBP among undergraduate healthcare students before implementation the educational package.
iv) To develop an Evidence Based Practice (EBP) educational package for Ugandan undergraduate health care professionals.
v) To implement an Evidence Based Practice educational package among undergraduate healthcare students at Makerere university college of health sciences
vi) To compare the perceived knowledge, skills, attitudes and behaviour of EBP among undergraduate healthcare professional students before and after implementation of the educational package

 Uganda 2021-02-24 2024-02-24 Medical and Health Sciences Degree Award
Cissy  Kityo
ID: UNCST-2021-R013663
 Ankle-Brachial Index Screening for Peripheral Artery Disease in Uganda: Building a Training Model and Exploring the Feasibility and Acceptability of Implementation Strategies, Version Date: September 30, 2020
REFNo: HS1028ES

General Objective;
The long-term goal of the project will be to provide insights into the barriers and facilitators of implementing PAD screening interventions in resource-poor settings. Early detection of subclinical cardiovascular disease—including PAD—may be a personalized and cost-effective way to reduce cardiovascular disease burden in low- and middle-income countries worldwide.

Specific aims;
-Assess knowledge of cardiovascular risk and subclinical disease
-Estimate the percentage of participants achieving competency in ABI screening techniques after receiving basic training
-Determine the perceived acceptability and feasibility of a PAD screening implementation strategy within the community


 Uganda 2021-02-22 2024-02-22 Medical and Health Sciences Non-degree Award
Obed Mugisha
ID:
USING REDUCED DOSES OF INTRAVENOUS NEOSTIGMINE/GLYCOPYRROLATE TO REDUCE ITS SIDE EFFECTS IN THE MANAGEMENT OF POST-DURAL PUNCTURE HEADACHE AT MBARARA REGIONAL REFERRAL HOSPITAL: A SINGLE-BLIND RANDOMIZED DOSE-FINDING STUDY
REFNo: HS1075ES

General Objective
To assess the role of Neostigmine/Glycopyrrolate combination dose reduction on the incidence of its associated side effects in the management of PDPH in obstetric post-operative patients at Mbarara Regional Referral Hospital.
Specific Objectives

1. To compare pain scores for PDPH in the three Neostigmine treatment groups (20, 10, and 5mcg/kg).
2. To compare the incidence of Neostigmine/Glycopyrrolate side effects in the standard dose group (20mcg/kg) with the reduced dose groups(10mcg/kg and 5mcg/kg).

 Uganda 2021-02-22 2024-02-22 Medical and Health Sciences Degree Award
Immaculate  Atukunda
ID: UNCST-2021-R013573
 WULIRA APP – OCCUPATIONAL HEARING LOSS AMONG INDUSTRIAL WORKERS IN KAMPALA, UGANDA.
REFNo: HS1237ES

1. To determine the prevalence of occupational hearing loss among workers in a steel and iron manufacturing industry in Kampala.
2. To assess the acceptability of using the Wulira App for hearing loss screening among workers in a steel and iron manufacturing industry.

 Uganda 2021-02-22 2024-02-22 Medical and Health Sciences Non-degree Award
Joweria Nambooze
ID: UNCST-2019-R001118
 BASELINE ASSESSMENT FOR NUTRITION INTERVENTIONS IN PALORINYA REFUGEE SETTLEMENT, OBONGI DISTRICT
REFNo: HS1241ES

The overall aim of this baseline study will be to assess the current status of nutrition outcomes, infant and young child feeding (IYCF) and livelihoods indicators among children and WRA, household food security and selected livelihood indicators among refugee households in Palorinya Refugee Settlement.

Uganda 2021-02-22 2024-02-22 Medical and Health Sciences Non-degree Award
Tim Colbourn
ID:
How does a multi-country, multilateral network focused on specific health care improvements evolve and what shapes its ability to achieve its goals?
REFNo: SS659ES

1. To characterise how the QCN initiative was conceptualized and brought together, explore its aims and ethos and understand the global context in which QED arose

2. To explore how the QCN is enacted as a strategy for linking global and national actors

3. To explore case study countries’ contexts and capacities, their interactions with the global QCN and the effects this has on the emergence of the national QCN programme

4. To characterise strategies adopted in countries, their scale, scope and focus, mechanisms of action, the evolution of programmes and what influences them

5. To map the activities of the national programmes at district level and examine the approach to intervention

6. To examine which key data are collected to evaluate the effect of the QCN and assess any effects of network activities


 UK 2021-02-18 2024-02-18 Social Science and Humanities Non-degree Award
Charles Drago Kato Drago
ID: UNCST-2021-R012897
 Establishment of a Biomarker research facility to first track the development of COVID19 novel diagnostics and treatment alternatives in Uganda
REFNo: HS1096ES

1. To establish a biomarker research facility at Makerere University. (Here we shall add more equipment capacity to the existing BSL3 lab at COVAB to execute COVID19 research).
2. To identify and evaluate key SARS-CoV-2 biomarkers in saliva, urine and blood with diagnostic/prognostic or therapeutic potential.
3. To develop biomarker panels (single or multiple analytes) with diagnostic/prognostic or therapeutic potential.

Uganda 2021-02-18 2024-02-18 Medical and Health Sciences Non-degree Award
Robert Ssekitoleko
ID: UNCST-2019-R001716
 Mobile Phone enabled Diagnostics for Infectious Disease Diagnosis: Low Cost Tools for Digital Health in Uganda
REFNo: SIR50ES

I. Understanding Digital Health for Infectious Disease in Low Resource Settings
II. Understanding Data Integrity and Security in Digital Health in Africa;
III. Exploring the Relationship between Data and Healthcare Policy;
IV. ICT Devices for Data Acquisition and Communication in East Africa with a focus on Uganda;
V. Capacity Strengthening - Educational Training underpinning Mobile Health.

 Uganda 2021-02-18 2024-02-18 Engineering and Technology Non-degree Award
Christine Aanyu
ID:
Alarm and response systems for addressing maternal and perinatal deaths in Eastern Uganda. A case of re-activation of MPDSR
REFNo: HS635ES

1) To explore the factors that facilitate or constrain the implementation of the MPDSR protocols
2) To develop a collaborative innovation to address the constraints of implementing MPDSR protocols
3) To enhance system wide learning through documenting and sharing of best practices for implementing MPDSR protocols

 Uganda 2021-02-17 2024-02-17 Medical and Health Sciences Non-degree Award
Peter Olupot-Olupot
ID:
Paracetamol for Acute Renal Injury in Severe Malaria Trial (PARIST)
REFNo: HS965ES

1. To conduct pharmacokinetic studies of paracetamol in patients with acute kidney injury in severe malaria.
2. To assess the feasibility of conducting AKI in severe malaria in Eastern Uganda.
3. To conduct safety and preliminary effectiveness study for use of paracetamol in ameliorating AKI in severe malaria.

 Uganda 2021-02-17 2024-02-17 Medical and Health Sciences Non-degree Award
Elizabeth Ekong Namukombe
ID:
Work-Based Learning for Baccalaureate Nurses in Uganda: Perception and Current Practice
REFNo: HS810ES

1. Explore the perception of baccalaureate nurses in Uganda on the ease of engaging in Work-based learning. 2. Explore the perception of baccalaureate nurses in Uganda on the usefulness of work-based learning. 3. Describe the current practice of Work-Based Learning among baccalaureate nurses in Uganda. 4. Determine any existing relationship between perceived usefulness and current practice of work-based learning among baccalaureate nurses in Uganda.
Uganda 2021-02-15 2024-02-15 Medical and Health Sciences Degree Award
Jane Namagga Kasozi
ID:
HIV-Associated Neurocognitive Burden: Feasibility of Implementing International HIV Dementia Scale into a Nurse-led HIV Model at TASO centres in southwestern Uganda
REFNo: HS814ES

1.To determine the prevalence of HIV- associated neurocognitive disorders using IHDS among PLWH attending TASO centres in rural Southwestern Uganda.

2.To identify the risk factors associated with HIV- associated neurocognitive disorders among PLWH attending TASO centres in rural Southwestern Uganda.

3.To assess the impact of an education intervention on nurses’ knowledge and skills regarding the use of IHDS in screening and managing HIV- associated neurocognitive disorders

4.To explore nurses' perceptions towards screening and managing HIV- associated neurocognitive disorders using IHDS among HIV positive clients attending TASO centres in rural Southwestern Uganda.

5.To determine the feasibility of implementing IHDS into a nurse-led model of HIV care.

Uganda 2021-02-15 2024-02-15 Medical and Health Sciences Degree Award
Andrew Ssemata
ID: UNCST-2023-R008259
 Exploring and understanding the life skills, sexual, reproductive and mental health needs among adolescents and young people with Spina bifida and Hydrocephalus disability in Sub Saharan Africa; a mixed methods study. (REMHAND)
REFNo: SS703ES

To explore and understand the life skills, sexual, reproductive and mental health needs among adolescents and young people with Spina bifida and Hydrocephalus disability and their significant others (siblings and parents) in Uganda.

Specific objectives
1. Explore and understand the life skills, sexual, reproductive and mental health needs among children and adolescents with disability.
2. Explore the SRH vulnerabilities, and experience (barriers and facilitators) to accessing SRH and mental health services.
3. Explore caregiver (parents and siblings) experiences and perspectives of the health implications of long‐term informal caregiving for children with SBH and disability.
4. Investigate the health, wellbeing and factors affecting the mental health of parents and siblings caring for children with disabilities.

 Uganda 2021-02-15 2024-02-15 Social Science and Humanities Non-degree Award
Bas van Boekholt
ID:
Turn-taking interactions in chimpanzees (Pan troglodytes schweinfurthii) in the wild
REFNo: NS153ES

To shed light on the evolution of language by providing the first systematic insights into the development of turn-taking in chimpanzees
 Netherlands 2021-02-15 2024-02-15 Natural Sciences Non-degree Award
Geoffrey Babughirana Babughirana
ID:
Effect of implementing the timed and targeted counselling (ttC) model on pregnancy outcome and Newborn survival in rural Uganda. A Quaisi experimental study in Hoima and Mansidi district
REFNo: HS574ES

To determine the effect of ttC on pregnancy outcomes and Newborn survival in Rural Uganda

1. To ascertain the extent to which ttC improves uptake of timely Goal Oriented ANC with a focus on the recommended 4 visits
2. To determine whether ttC contributes to the recommended hygienic birthing practices
3. To establish the extent to which ttC improves essential new-born care practices (ENC) during the new born period
4. To ascertain the extent to which ttC fosters positive male involvement in Pregnancy and New Born care
5. To ascertain the relationship between ttC implementation and appropriate pregnancy weight gain by end of Pregnancy.
6. To ascertain the relationship between ttC implementation and appropriate birth weight

Uganda 2021-02-12 2024-02-12 Medical and Health Sciences Non-degree Award
Francis Ssali
ID: UNCST-2021-R012134
 A5379: B-ENHANCEMENT OF HBV VACCINATION IN PERSONS LIVING WITH HIV (BEe-HIVe): Evaluation of HEPLISAV-B
REFNo: HS622ES

• To compare the week 12 seroprotection response (SPR) of a two-dose regimen of HEPLISAV-B (Group A, Arm 1) versus the week 28 SPR of a standard three-dose regimen of ENGERIX-B (Group A, Arm 3) in Hepatitis B virus (HBV) vaccine-experienced participants living with HIV (Group A).

• To compare the week 28 SPR of a three-dose regimen of HEPLISAV-B (Group A, Arm 2) versus a standard three-dose regimen of ENGERIX-B (Group A, Arm 3) in HBV vaccine-experienced participants living with HIV (Group A).

• To determine the week 28 SPR of a three-dose regimen of HEPLISAV-B in HBV vaccine-naïve participants living with HIV (Group B).

• To describe adverse events (AEs) reported in each study arm (Groups A and B, separately) over the duration of the study.


Uganda 2021-02-12 2024-02-12 Medical and Health Sciences Non-degree Award
Clare Cheromoi -
ID:
Interrogating Political Corruption in Post-Independent Uganda: A Historical Perspective, 1962-2017.
REFNo: SS488ES

(1) To describe the transhistorical patterns and evolution of political corruption in Uganda between 1962 and 2017.
(2) To examine the political actors involved in the political corruption scandals experienced in post-independent Uganda.
(3) To explore the proximate and underlying causes of political corruption that are transhistorical in post-independent Uganda.
(4) To assess the transhistorical interrelationships between political corruption and anticorruption responses in post-independent Uganda.

Uganda 2021-02-12 2024-02-12 Social Science and Humanities Degree Award
Leonard Omadang
ID:
PREVALENCE, RISK FACTORS AND ECONOMIC IMPACT OF CYSTIC ECHINOCOCCOSIS IN LIVESTOCK HERDS AMONG THE PASTORAL AND AGRO-PASTORAL COMMUNITIES IN UGANDA
REFNo: A87ES

i. To determine the prevalence of Echinococcosis in livestock slaughtered in selected abattoirs in Uganda.

ii. To determine risk factors associated with cystic echinococcosis in livestock in selected pastoral and agro-pastoral communities in Uganda.

iii. To determine the economic losses of CE in livestock kept by the pastoral and agro-pastoral communities in Uganda.

 Uganda 2021-02-12 2024-02-12 Agricultural Sciences Degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
 Implementation of a Quality Improvement Intervention to Improve Discharge Practices for Children recovering from Severe Infection Using a District model in Gulu and Rukungiri Districts
REFNo: HS926ES

The main objective in implementing this program is to improve patient outcomes for children recovering from Severe Infection though implementation of a multi-faceted quality improvement intervention targeting health workers, care givers and the community health workers.
Specifically we intend to :
1. Evaluate how a targeted behavior change intervention can affect health worker behaviors and facility readiness to assess and manage children during the discharge process.
2. To evaluate the effectiveness of a facility-based linkage to a community based follow-up system to improve post-discharge care for children recovering from severe infections

 Uganda 2021-02-12 2024-02-12 Medical and Health Sciences Non-degree Award
Fred  Bulamba
ID: UNCST-2020-R014888
 The three delays model and Postpartum haemorrhage: a mixed-methods study at a teaching hospital in eastern Uganda
REFNo: HS932ES

Overall aim
The overall aims of this study are to understand how delays impact development of primary PPH (using the three-delays model) and how available preventive and therapeutic interventions are administered.

 Uganda 2021-02-12 2024-02-12 Medical and Health Sciences Non-degree Award
Janet Lewis I
ID:
Reducing Prejudice Against Refugees Pilot
REFNo: SS662ES

The vast majority (85%) of the world’s political refugees live in developing countries, according to UNHCR. As of early 2019, Uganda was home to over one million refugees from South Sudan, and had the largest refugee/asylum-seeker population in Africa (ACCORD 2019). Uganda has a strong national commitment to hosting refugees that is reflected in its immigration policies, leading some to call it a “melting pot” of regional nationalities. Still, its population faces challenges absorbing these refugees that are common to host countries. Relations are often strained between the refugee population and Ugandans, some of who perceive refugees as unwelcome competition for local resources and services (World Vision 2018; UNHCR 2018; ACCORD 2019).
This study will allow us to better understand the perceptions of Ugandans towards South Sudanese refugees, and measure both the extent of anti-refugee prejudice there and whether a perspective-taking intervention is effective at reducing prejudice. This knowledge will be crucial for understanding how best to design a later, larger study, which could substantially advance knowledge about prejudice reduction towards refugees in Uganda.
Furthermore, this study will provide a useful indication about whether our full version of this study will be able to measure spillover of the treatment through social networks; we will ask respondents in our endline survey about whether and with whom respondents discussed the intervention. Prejudicial attitudes are socially reinforced; changing one person’s mind may be difficult if that person’s peers still hold prejudicial beliefs. Likewise, if many of one’s peers have begun to reconsider their own prejudices, one may be encouraged to do so as well. Our prior work leads us to expect the information to spread widely, and some change in attitudes and behavior, but only for those connected to a treatment recipient via certain kinds of social ties (Larson and Lewis 2017, 2018). Practitioners often assume that interventions spread from a subset of individuals to their broader community through felicitous spillovers. If this pilot is successful, our full study will be among the first to measure whether and how this occurs for prejudice reduction through networks. This knowledge could, among other things, lead to more efficient designs of community prejudice-reduction projects. Moreover, even if spillover effects are not present, the full study will be able to detect how news of the intervention spreads through local networks. Doing so will provide rare, direct evidence of information dissemination through word-of-mouth networks, which is useful for the design of programs aimed at seeding any type of public service message – from news intended to diffuse conflicts, to information about a new technology that promises to better hold politicians accountable or improve public health.

Our pilot study therefore addresses four questions:
(1) What is the extent of anti-refugee prejudice among Ugandans living in villages in West Nile?
(2) Do positions towards refugees correlate with their positions in village social networks?
(3) Can a brief conversation oriented towards taking the perspective of South Sudanese refugees reduce Ugandans’ prejudice toward them? If so, does the effect persist after 2-3 weeks?
(4) To what extent does news spread about this perspective-taking exercise, and through which types of contacts?
 USA 2021-02-12 2024-02-12 Social Science and Humanities Non-degree Award
AGGREY DHABANGI
ID:
Hemolytic Disease of the Newborn in Uganda: Burden and Clinical Characteristics (Short title: HDN in Uganda)
REFNo: HS1089ES

To determine the prevalence of HDN due to RhD among newborn infants with jaundice admitted to Kawempe National Referral hospital in Uganda.
 Uganda 2021-02-12 2024-02-12 Medical and Health Sciences Non-degree Award
Peter Elyanu James
ID: UNCST-2021-R013210
 PREVALENCE AND RISKS ASSOCIATED WITH METABOLIC SYNDROME IN CHILDREN AND ADOLESCENTS LIVING WITH HIV IN UGANDA. A PILOT STUDY
REFNo: HS1128ES

i To determine the prevalence of MetS among children and adolescents living with HIV in Uganda.
ii To identify risks factors for the development of MetS in children and adolescents living with HIV.

Uganda 2021-02-12 2024-02-12 Medical and Health Sciences Non-degree Award
Abner Tagoola
ID:
A phase 2b study to Evaluate the safety and efficacy of IMR-687 in subjects with sickle cell disease.
REFNo: HS1092ES

1. To evaluate the fetal Hb (Hbf) response to IMR-687 versus placable.

2. To evaluate of IMR-687 versus placable
 Uganda 2021-02-11 2024-02-11 Medical and Health Sciences Non-degree Award
Afiz Kibuuka Kibuuka
ID: UNCST-2021-R012755
 A Phase 2b Study to Evaluate the Safety and Efficacy of IMR-687 in Subjects with Sickle Cell Disease
REFNo: HS1150ES

Objectives:
Primary Objectives
• To evaluate the fetal hemoglobin (HbF) response to IMR-687 versus placebo
• To evaluate the safety of IMR-687 versus placebo Seconduy Efficacy Objectives
• To evaluate the effect of IMR-687 versus placebo on HbF-associated biomarkers
• To evaluate the effect ofIMR-687 versus placebo on indices of red cell hemolysis
• To evaluate the effect ofIMR-687 versus placebo on indices of white blood cell (WBC) adhesion
To evaluate the effect of IMR-687 versus placebo on the incidence of vaso-occlusive crises (vocs)
• To evaluate the effect of IMR-687 versus placebo on quality of life measures Pharmacokinetic•Óbjectives
• To evaluate the PK ofIMR-687 and any major circulating metabolites
Exploratory Efficacy Objectives
To evaluate the effect of IMR-687 versus placebo on changes in red blood cell (RBC) characteristics and total Hb e To evaluate the effect of IMR-687 versus placebo on renal function
• To evaluate the effect of IMR-687 versus placebo on indices associated with cardiovascular pathophysiology and ischemic stroke risk

 Uganda 2021-02-11 2024-02-11 Medical and Health Sciences Non-degree Award
Casim Tolo Umba
ID: UNCST-2021-R012658
 Action Towards Reducing Aquatic snail-borne Parasitic diseases (ATRAP)
REFNo: NS128ES

The main objective of the project is to improve Health through the prevention and mitigation of risks that originate at the interface between humans, animals and the environment. In this project we want to increase the capacity to prevent infections by snail-borne diseases in western Uganda. The strategic objectives are as follows:
1. To strengthen scientific research capacity.
2. To strengthen physical and virtual diffusion of scientific research
results to the larger scientific community
3. To raise awareness about snail borne diseases to the general public.
4. To support good governance, based on the scientific results.
5. To develop synergies and complementary activities among partners through multi-partner governance and coordination


 Uganda 2021-02-10 2024-02-10 Natural Sciences Degree Award
MIRIAM NAKALEMBE
ID: UNCST-2019-R000824
 Designing and Piloting of a Mobile-based Transport Technology linking Mothers to Health Facilities to Reduce Maternal and New-born Deaths in Uganda during the COVID-19 Pandemic.
REFNo: HS1148ES

1. To identify the existing automated maternal services apps and assess the extent to which they provide near real-time information and communication between mothers and the transporters at community level.
2. To develop a mobile-based transport technology that improves two-way communication between mothers and the transporters at community levels
3. To pilot the mobile-based transport technology for its usability and acceptability

 Uganda 2021-02-10 2024-02-10 Medical and Health Sciences Non-degree Award
Anthony Nuwa
ID:
Evaluating the feasibility, acceptability and protective efficacy of seasonal malaria chemoprevention in two districts in Karamoja, Uganda
REFNo: HS1182ES

Objective 1: To document the adaptation of SMC in Karamoja region in Uganda
Objective 2: To Assess the process of implementing SMC in Uganda, with regards to coverage and quality of implementation
Objective 3: To assess the acceptability of SMC among policy makers, implementers, and beneficiaries.
Objective 4: To determine the impact of SMC on malaria incidence and prevalence among children under 5 years in the Karamoja region and assess the protective efficacy of SPAQ
Objective 5: To analyse cost of SMC delivery to children 3-59 months in Karamoja region
Objective 6: Monitor the safety of sulfadoxine-pyrimethamine (SP) and amodiaquine (AQ) when used in SMC among children 3-59 months in Karamoja region.

 Uganda 2021-02-10 2024-02-10 Medical and Health Sciences Non-degree Award
Noah Kiwanuka
ID: UNCST-2021-R010125
 Capturing spatial patterns of new M. tuberculosis infection in Kampala, Uganda
REFNo: HS1230ES

To map the geo-spatial incidence of Mtb infections in a prospective community cohort study of HIV+ and HIV- adults in Kampala Uganda. GPS tracking technology will be used to trace and map subjects to locate areas of high Mtb transmission, or hotspots. Study participants without tuberculous infection will be followed for IGRA/TST conversion for up to 2 years with serial plasma samples taken quarterly.
To determine and validate whether a defined plasma signature found in other studies can identify recent Mtb infection in persons who developed LTBI. Using a paired analysis, we will evaluate baseline and follow-up samples within individuals to determine whether changes associated with new Mtb infection in the community can be detected in plasma with published and newly developed biomarkers. Using a nested case control design, we will compare incident infections with randomly selected controls from the cohort who did not convert

 Uganda 2021-02-10 2024-02-10 Medical and Health Sciences Non-degree Award
Daphine Namara Arinaitwe Namara
ID:
The Risk of Diabetes and pre-Diabetes associated with use of Dolutegravir based Antiretroviral Therapy among adult persons living with HIV: A Case-control study at Mulago ISS clinic, Kampala, Uganda
REFNo: HS1077ES

Primary objective: To determine the risk of DM and pre-DM associated with the use of DTG-based ART among adult PLHIV at Mulago ISS Clinic.
Secondary objective; To determine other risk factors for DM and pre-DM among PLHIV adult PLHIV at Mulago ISS Clinic.

 Uganda 2021-02-09 2024-02-09 Medical and Health Sciences Non-degree Award
Christine Nalwadda Kayemba
ID: UNCST-2020-R014220
 A BASELINE ASSESMENT FOR THE ADVANCING SEXUAL REPRODUCTIVE HEALTH AND RIGHTS (ANSWER) PROGRAM IN THE WEST NILE AND ACHOLI SUBREGIONS IN UGANDA
REFNo: HS1079ES

General objective

To analyse the situation of sexual and reproductive health and rights (SRHR) aspects as well as GBV in the intervention districts of UNFPA’s programme targeting to advance SRHR in the Acholi and West Nile sub regions in Uganda, in order to generate scientific evidence that will inform evidence based planning, implementation and form a basis for monitoring and evaluation of the program interventions.

Specific objectives

1.To conduct Health facility assessment at targeted health facilities in West-Nile and Acholi sub regions in regards to offering quality equitable SRHR services (FP/Maternal health/Post abortion Care, HIV testing and Post GBV) that is responsive to the needs of women, girls, boys and men, refugees, and people with disabilities

2.To undertake an assessment of SRHR Knowledge, Attitudes and Practices (KAP) of adolescents and youth in school including refugees and people with disabilities from a sample of 1,800 targeted schools (primary & secondary) in the study districts on GBV and SRHR.

3.To conduct an assessment of SRHR Knowledge, Attitudes and Practices (KAP) of adolescents and youth out of school including refugees and people with disabilities in the study districts on GBV and SRHR.

4.To conduct a budget and expenditure analysis of key sectors at national level and the district local governments focusing on implementation of and accountability towards the demographic dividend priorities.
 Uganda 2021-02-09 2024-02-09 Medical and Health Sciences Non-degree Award
RUTH NAKATO
ID:
A model for assessing the Banking Sector Employees’ Ethical Behavior towards Cyber security.
REFNo: SIR34ES

1. To examine the extent to which cardinal virtue constructs can influence the cyber security behavioral intention of employees towards cyber security ethical behavior in commercial banks in Uganda. 2. To analyze the moderation effect of ethical climate on the virtue constructs in connection with the behavioral intention of employees towards cyber security ethical behavior in commercial banks in Uganda. 3. To examine the mediation effect of behavior intention on the influence of virtue ethics towards cyber security ethical behavior in commercial banks in Uganda. 4. To develop a model for assessing the Employees’ Ethical Commitment and Behavior towards Cyber security in commercial banks in Uganda. 5. To test and validate the developed model.
Uganda 2021-02-08 2024-02-08 Engineering and Technology Degree Award
Tadele Yadesa Mekuriya
ID: UNCST-2022-R010338
 Incidence, predictors and risk prediction of adverse drug reactions among inpatients 60 years and older at Mbarara Regional Referral Hospital, Mbarara, Uganda
REFNo: HS992ES

1. To determine the incidence and prevalence of ADRs among elderly inpatients at MRRH
2. To characterize (types, severity and preventability) the ADRs detected among elderly inpatients at MRRH
3. To determine the risk factors of ADRs among elderly inpatients at MRRH
4. To develop and validate an ADR risk score tool (to be named as PADR-HE) for elderly inpatients at MRRH
 Ethiopia 2021-02-08 2024-02-08 Medical and Health Sciences Degree Award
Angua Amis Mao
ID:
Energy access as a dividend for designing just transition pathways (EAJT)
REFNo: SIR48ES

1. To assess the effectiveness of different renewable energy technologies in accelerating green jobs creation and a low carbon trajectory; 2. To analyse the equity and distributional implications of energy transition in vulnerable communities across gender, age, and income groups;

3. To develop potential financial and business models to deliver a just transition pathway; and

4. To explore appropriate policy and regulatory frameworks required to support a just transition at multiple levels from grassroots to the national and regional level.

 Uganda 2021-02-08 2024-02-08 Engineering and Technology Non-degree Award
David Musoke
ID:
Distribution of antibiotic profiles and antibiotic resistance associated with tuberculosis treatment regimens from wastewater treatment plants in Africa
REFNo: HS1017ES

Specific objectives
1. To determine the profile and concentration of antibiotics used in TB treatment in raw and treated sewage.
2. To investigate the efficiency of the WWTP treatment process in relation to removal of antibiotics post chlorination.
3. To determine the prevalence of antibiotic resistant bacteria (ARB) in raw and treated wastewater in these WWTPs.
4. To evaluate the prevalence of antibiotic resistance genes (ARGs) in raw and treated wastewater.

 Uganda 2021-02-08 2024-02-08 Medical and Health Sciences Non-degree Award
Francis Ssali
ID: UNCST-2021-R012134
 An open-label, roll-over study with rilpivirine in combination with a background regimen containing other antiretrovirals (ARVs) in human immunodeficiency virus type 1 (HIV-1) infected subjects who participated in rilpivirine pediatric studies
REFNo: HS1083ES

In view of the primary objective of the study to provide continued access to RPV, no primary endpoint is defined for this study.Secondary Endpoint
The secondary endpoints are applicable for all subjects until data collection is terminated, as indicated.
Major Secondary Endpoints
The proportion of subjects experiencing adverse events (AEs) considered to be at least possibly related to RPV, AEs leading to discontinuation, serious adverse events (SAEs), pregnancies, and grade 3/4 rash regardless of causality throughout the study. Results of routine safety laboratory tests will only be collected if related to these types of AEs.
Other Secondary Endpoint
The proportion of subjects maintaining viral suppression (ie, <50 HIV-1 RNA copies/mL) based on available viral load data throughout the study. In case of virologic failure, emergence of resistance will also be evaluated based on available genotype/phenotype data.


 Uganda 2021-02-08 2024-02-08 Medical and Health Sciences Non-degree Award
Jonathan Mwiindi Thuranira
ID:
EMERGENCY CESAREAN SECTION AND LENGTH OF STAY IN HOSPITALS IN UGANDA
REFNo: HS1093ES

1. To determine if payer-type (SAFE vs. self-pay) is associated with the decision to delivery interval (DDI) for rural Uganda women undergoing an emergency C-section in Nyakibale Hospital and Rushoroza Hospital. The DDI is the first phase of the aggregated LOS. 2. To determine if payer-type (SAFE vs. self-pay) is associated with the aggregate LOS for rural Uganda women undergoing an emergency C-section in Nyakibale Hospital and Rushoroza Hospital in rural Uganda while adjusting for the Decision to Delivery Interval (DDI). 3. To describe the experience of eight young mothers (aged 18-25) having their second (or more) C-Section delivered by emergency C-section in Southwest Uganda under the SAFE program during April 2020.
 Kenya 2021-02-08 2024-02-08 Medical and Health Sciences Degree Award
Bonaventure Ssebyanzi Wasswa
ID:
PRIMARY SCHOOL SUPPORT SYSTEMS TO DEAF CHILDREN LEADING TO THEIR TRANSITION TO POST-PRIMARY EDUCATION IN UGANDA
REFNo: SS590ES

(i) To investigate the support systems for deaf children at the completion of primary school studies.
(ii) To examine the situation of deaf children at the completion of primary studies.
(iii) To explore the self of deaf children at the completion of primary studies.
(iv) To establish the strategies for transition to post-primary level of deaf children at the completion of primary studies.

Uganda 2021-02-05 2024-02-05 Social Science and Humanities Degree Award
Alex Taremwa Taremwa
ID: UNCST-2020-R014302
 VIABILITY OF DIGITAL SUBSCRIPTION IN EAST AFRICA – AN ANALYSIS OF VIUSASA AND CHIMPREPORTS’ PAYWALLS
REFNo: SS629ES

1. To identify critical success factors for subscription-based models in digital media platforms.
2. To establish the barriers to subscription uptake among digital media in East Africa.
3. To assess the critical success factors against the ChimpReports and Viusasa’s strategies.
4. To analyse the consumption habits of audiences in line with payment for digital content on Viusasa and Chimp.

Uganda 2021-02-05 2024-02-05 Social Science and Humanities Degree Award
Joseph Lutaakome
ID: UNCST-2020-R008323
 An open-label, roll-over study with rilpivirine in combination with a background regimen containing other antiretrovirals (ARVs) in human immunodeficiency virus type 1 (HIV-1) infected subjects who participated in rilpivirine pediatric studies
REFNo: HS1013ES

Primary Endpoint
The primary objective of the study is to provide continued access to RPV, however there is no primary endpoint defined for this study.
Secondary Endpoint
The secondary endpoints are applicable for all subjects until data collection is terminated, as indicated.
Major Secondary Endpoints
The proportion of subjects experiencing adverse events (AEs) considered to be at least possibly related to RPV, AEs leading to discontinuation, serious adverse events (SAEs), pregnancies, and grade 3/4 rash regardless of causality throughout the study. Results of routine safety laboratory tests will only be collected if related to these types of AEs.
Other Secondary Endpoint
The proportion of subjects maintaining viral suppression (ie, <50 HIV-1 RNA copies/mL) based on available viral load data throughout the study. In case of virologic failure, emergence of resistance will also be evaluated based on available genotype/phenotype data.
 Uganda 2021-02-05 2024-02-05 Medical and Health Sciences Non-degree Award
Jennifer Serwanga
ID: UNCST-2024-R002056
 Preparation of an Inactivated covid-19 vaccine at UVRI for pre-clinical evaluations at COVAB and an Outsourced primate centre
REFNo: HS1018ES

Collect nasopharyngeal swab of circulating virus strains b. Isolate local and globally representative wildtype SARS-CoV2 stocks c. Generate inactivated SARS-CoV-2 products (The Vaccine). d. Generate SARS-CoV-2 and other b-CoVs pseudovirus stocks
e. Develop assays to distinguish SARS-CoV-2 binding antibodies
f. Develop assays to distinguish SARS-CoV-2 functional neutralizing antibodies
g. Assess inactivated vaccine in Humanized ACE2 mice challenge models
h. Challenge Macaque models to assess safety, immunogenicity and protectiveness
i. Assess immunized mice for vaccine-induced antibody responses
j. Assess immunized mice for vaccine induced cellular responses
k. Assess immunized mice plasma for inflammatory responses
l. Immuno/histopathology of immunized mice organs/tissues
m. Train and develop capacity for skill transfer
The research questions are;
• Will the inactivated vaccine protect challenged mice against developing COVID-19
disease?
• Will the vaccine elicit potent neutralizing antibodies against diverse SARS-CoV-2
strains and how potent are these antibodies?
• Will the vaccine protect the challenged mice against severe inflammatory responses
and organ pathology?
• Will the inactivated vaccine elicit potent and protective effector T -Cell responses?
 Uganda 2021-02-05 2024-02-05 Medical and Health Sciences Non-degree Award
Athanansio Bashaija
ID:
Occupational Stress, Hope, and Alcohol Use among Secondary School Teachers in Greater Bushenyi, Uganda
REFNo: SS671ES

To examine the level of occupational stress among secondary school teachers in Greater Bushenyi.
To assess the level of alcohol use among secondary school teachers in Greater Bushenyi.
To examine the level of hope among secondary school teachers in Greater Bushenyi.
To determine the relationship between occupational stress and alcohol use among secondary school teachers in Greater Bushenyi.
To establish the moderation effect of hope on the relationship between occupational stress and alcohol use among secondary school teachers in Greater Bushenyi.

 Uganda 2021-02-05 2024-02-05 Social Science and Humanities Degree Award
Victor Musiime
ID: UNCST-2021-R013794
 A Phase 2b Study to Evaluate the Safety and Efficacy of IMR-687 in Subjects with Sickle Cell Disease (IMR-SCD-301)
REFNo: HS1119ES

Primary Objectives:
1. To evaluate the HbF response to IMR-687 versus placebo
2. To evaluate the safety of IMR-687 versus placebo

Secondary Efficacy Objectives:
1. To evaluate the effect of IMR-687 versus placebo on HbF-associated biomarkers
2. To evaluate the effect of IMR-687 versus placebo on indices of red cell hemolysis
3. To evaluate the effect of IMR-687 versus placebo on indices of RBC adhesion
4. To evaluate the effect of IMR-687 versus placebo on the incidence of VOCs
5. To evaluate the effect of IMR-687 versus placebo on quality of life (QoL) measures

Pharmacokinetic Objectives:
To evaluate the PK of IMR-687 and any major circulating metabolites

Exploratory Efficacy Objectives:
1. To evaluate the effect of IMR-687 versus placebo on changes in RBC characteristics and total Hb
2. To evaluate the effect of IMR-687 versus placebo on renal function
3. To evaluate the effect of IMR-687 versus placebo on indices associated with cardiovascular pathophysiology and ischemic stroke risk

Uganda 2021-02-05 2024-02-05 Medical and Health Sciences Non-degree Award
Sheila Balinda Nina
ID: UNCST-2021-R013804
 Novel Adenovirus-based Vaccine for Uganda SARS COV-2 viruses
REFNo: HS1153ES

To develop a Novel SARS-Cov-2 Adeno-Vectored Vaccine against COVID-19. Briefly, we propose two adenovirus vector constructs using both S1 and S2 SARS-CoV-2 glycoproteins previously generated for the subunit vaccine design at CoVAB. Alternatively, these genes can also be amplified directly from the genome at the UVRI laboratories. Although most of the world is focused on SARS-CoV-2 Spike as an antigen, there are additional viral capsid proteins that should also be considered including the Envelope and N proteins.
 Uganda 2021-02-05 2024-02-05 Medical and Health Sciences Non-degree Award
Kinyaa Rufina Ayia
ID:
Teachers use of formative assessment in teaching reading comprehension in transition class, Moyo Sub County, Moyo district.
REFNo: SS582ES

To investigate teachers’, use of formative assessment in teaching reading comprehension in the transition class.
> To examine the strategies teachers’, use for formative assessment in reading comprehension in the transition class.
> To establish the challenges teachers’ encounter when administering formative assessment in reading comprehension in the transition class

 Uganda 2021-02-04 2024-02-04 Social Science and Humanities Degree Award
AGNES NAGGIRINYA BWANIKA
ID: UNCST-2019-R001126
 DETERMINATION OF CROSS-SPECIES TRANSMISSION OF COVID-19 AT ANIMAL-HUMAN INTERFACE USING A ONE HEALTH APPROACH FOR IMPROVED DISEASE SURVEILLANCE AND CONTROL
REFNo: HS905ES

General Objectives
To assess existence of SARS-CoV-2 in domestic and wild animals (in Amuru/ Greater Rakai and UWEC) and corona virus antibody in humans (Amuru/ Greater Rakai) with no history of infection, using a one health approach.
Specific Objectives
• Assess prevalence of SARS-CoV-2 in wild, livestock and companion animals, which may act as reservoirs of the causative agent in areas with confirmed cases of COVID-19 in Uganda
• Assess prevalence of the virus-specific antibodies in humans with no known history of contact with confirmed COVID-19 cases
• To determine the genetic relatedness between the human virus isolates with those obtained from the animals in order to confirm cross-host species transmission in Amuru and Greater Rakai districts.

 Uganda 2021-02-04 2024-02-04 Medical and Health Sciences Non-degree Award
Caroline Delaire
ID:
Evaluating the potential of point-of-collection chlorination and village savings and loans associations to improve water safety management in rural Uganda
REFNo: SIR47ES

1. To evaluate the effectiveness of an inline handpump chlorinator (PurAll 50H) at improving water safety.
2. To understand the contexts that are favorable for bundling maintenance and chlorination, and the contexts where bundling is not appropriate.
3. To understand the contexts where VSLA-managed “water funds” are successful at increasing financial resources available for handpump maintenance, and the contexts where this strategy is less effective.

 France 2021-02-04 2024-02-04 Engineering and Technology Non-degree Award
Eve  Namisango
ID: UNCST-2021-R014038
 Health Systems Strengthening through person-centred care: development of a feasible and acceptable theory-based workforce approach to improve quality
REFNo: HS1000ES

i) To adapt the conceptual framework of person-centred care for serious illness (MONTHS 1-10).
ii) To determine professional views on the feasibility, acceptability and necessary requirements for health systems change to deliver person-centred and values-based care (MONTHS 11-12).
iii) To design a systems-oriented strategy to enhance the person-centredness of care based on evidence from objectives i+ii (MONTHS 13-16).
iv) To refine and determine psychometric properties of a brief measure of person-centredness for subsequent evaluation of the health systems strengthening strategy (MONTHS 17-24).

Uganda 2021-02-04 2024-02-04 Medical and Health Sciences Non-degree Award
Nathan Fiala
ID: UNCST-2022-R009060
 “An exploration of groundnut Seed Quality Along the distribution chain in Uganda.”
REFNo: A109ES

The general objective of this study is to conduct an analysis of seed quality along the supply chain of groundnuts in Uganda. The selected crop for this study is important and the seed system is largely informal. Groundnuts is nearly 100% self-pollinating (98-99%) and farmers keep the seeds often beyond the recommended replacement period.
 USA 2021-02-04 2024-02-04 Agricultural Sciences Non-degree Award
Aloysius Ssennyonjo Ssennyonjo
ID: UNCST-2021-R013504
 COVID-19 Lockdown in Slums Informal Urban Settlements: Social and- Health Effects, Coping Strategies and Lessons for Improving the Livelihood of the Urban Poor in Kisenyi, Kampala, Uganda
REFNo: HS887ES

General Objective
To explore the social and health effects of COVID-19 lockdown, coping strategies and lessons for improving the livelihood of the urban poor in Kisenyi, Kampala, Uganda
Specific Objectives

1. To assess the immediate health effects of COVID 19 lockdown among the urban poor in Kampala
2. To assess the immediate social effects of COVID 19 lockdown among the urban poor in Kampala
3. To explore how the urban poor households coped with selected effects of the COVID-19 lockdown
4. To explore lessons for mitigating the effects of COVID 19 lockdown in the immediate recovery phase and consider implications for long term programming for urban poor.

 Uganda 2021-02-02 2024-02-02 Medical and Health Sciences Non-degree Award
Julius Tumusiime
ID:
Dynamics of Snail Species and Interventions to Reduce associated Schistosoma and Fasciola Parasitic Infections: A Citizen Scientists’ approach in Western Uganda
REFNo: NS148ES

1. determining the diversity and spatial-temporal distribution of freshwater snail intermediate hosts of Schistosoma/Fasciola parasites.
2. evaluating the diversity of Schistosoma/Fasciola trematodes shed per snail host: comparison of traditional and molecular methods.
3. examining the biotic (macrophyte, vertebrate hosts) and abiotic (rainfall, pH, DO, EC, temperature, inorganic ions) factors that influence the occurrence of Schistosoma/Fasciola snail hosts.
4. assessing the dependability/reliability of citizen researchers’ malacological survey, snail species identification and disease risk hotspot identification.

Uganda 2021-01-29 2024-01-29 Natural Sciences Degree Award
Alex Saturday
ID: UNCST-2023-R007459
 INVESTIGATION OF SPATIO-TEMPORAL VARIATION IN BIOLOGICAL AND PHYSICO-CHEMICAL WATER QUALITY PARAMETERS IN LAKE BUNYONYI, SOUTH-WESTERN UGANDA
REFNo: NS149ES

i. To determine the Spatio-temporal variations of bacterial fecal indicators of water in Lake Bunyonyi.
ii. To assess the Spatio-temporal variations in phytoplankton composition and biomass in the water of Lake Bunyonyi.
iii. To determine the Spatio-temporal variations of physicochemical quality of water in Lake Bunyonyi.
iv. To examine the seasonal variations of the trophic state conditions of Lake Bunyonyi ecosystem
v. To investigate the processes that governs nutrient dynamics in Lake Bunyonyi ecosystem.

Uganda 2021-01-28 2024-01-28 Natural Sciences Degree Award
Emily Otali
ID:
A study of health and forage patterns of wild African honeybees (Apis mellifera scutellata) and their impact on the survival of Kibale National Park, its threatened chimpanzees and elephants.
REFNo: A82ES

The general objective for this study is to engage farmers and students living around Kibale National Park, Uganda, in an accessible and culturally relevant participatory science project that collects and analyzes data measuring colony health and foraging plants of wild African honeybees for a period of two years. This will be achieved through:
• Developing participatory science project appropriate for rural Ugandan farmers and partnering students.
• Establishing baseline colony health and forage patterns for the wild African honey bee in the Kibale National Park ecosystem.
• Determining if colony health and forage patterns for the wild African honey bee knowledge will help achieve maximum honey yields and increased forage diversity.

 Uganda 2021-01-28 2024-01-28 Agricultural Sciences Non-degree Award
Jackson Mukonzo
ID: UNCST-2021-R013916
 IDENTIFICATION, VALIDATION AND OPTIMIZATION OF AVAILABLE DRUG MOLECULES FOR CLINICAL TREATMENT OF COVID-19.-IVCOM
REFNo: HS1065ES

1. Explore the clinical use of combination anticoagulant: lower dose aspirin and ivermectin, an FDA-approved anti-parasitic drug therapy in treatment of COVID-19 patients in an exploratory randomized trial.
2. To identify target molecules through testing and screening for SARS-CoV-2 activity of existing substances, molecules or formulations on basis of registered activity claims or scientific evidence for anti- SARS-CoV-2 activity including herbal preparations, quinolone derivatives (chloroquine and hydroxyquinoline) in combination with zinc, HIV entry and protease inhibitors, HCV protease inhibitors and entry inhibitors as well as agents with inhibitory and down regulatory effect on ACE2 and those that might be identified thorough literature search.
3. Use bioinformatics tools to perform structural optimization of molecules identified in objective 2 above for efficacy and safety of COVID-19 patents and conduct early phase clinical trials on the resulting molecules.
Uganda 2021-01-28 2024-01-28 Medical and Health Sciences Non-degree Award
Alex Mabirizi
ID:
ASSESING THE EFFECT OF CONCURRENT VACCINE ADMINISTRATION FOR PESTE DES PETITS RUMINANTS, CAPRIPOX AND CONTAGIOUS CAPRINE PLEUROPNEUMONIA ON IMMUNITY OF SHEEP AND GOATS IN UGANDA
REFNo: A106ES

1. To determine antibody titres against PPR, CCPP and Capripox Virus following single and concurrent administration of two or three vaccines.
2. To determine cytokine responses to PPR, CCPP and Capripox Virus following single and concurrent administration of two or three vaccines.

Uganda 2021-01-28 2024-01-28 Agricultural Sciences Degree Award
faith mbabazi musinguzi
ID:
Role conflict and Burnout among university administrators in selected universities in Uganda
REFNo: SS552ES

4. To assess the influence of role conflict on burnout for administrators across universities.,3. To establish the administrators’ experience with role conflict and burnout among administrators.,2. 2. To examine the degree to which role conflict constructs predict burnout among non-academic administrators.,1.To establish the extent to which role conflict constructs predict burnout among academic administrators.,
 Uganda 2021-01-27 2024-01-27 Social Science and Humanities Degree Award
Ponsiano Ocama
ID: UNCST-2019-R000440
 Clinical and immunological impact of Schistosoma mansoni infection and treatment on the course of chronic hepatitis B virus (HBV) infection in HIVuninfected patients in Uganda
REFNo: HS1002ES

To determine Clinical and immunological impact of Schistosoma mansoni (Sm) infection and treatment on the course of chronic hepatitis B virus (HBV) infection in Uganda. This will be done through the following aims: Aim 1: To define and quantify Sm infection, treatment response, and reinfection rates within a cohort of chronic HBV patients Aim 2: To determine the impact of Sm infection and treatment on HBV virological markers, disease stage, and longer-term progression among urban Ugandans Aim3: To determine if HBV-specific immunological responses in the periphery and within the liver are altered in response to Sm infection and treatment

Uganda 2021-01-27 2024-01-27 Medical and Health Sciences Non-degree Award
Miriam Nakalembe
ID: UNCST-2021-R014040
 Understanding CIN2+ among HIV infected women after LEEP: An epidemiological and immunohistochemical study
REFNo: HS1154ES

1. To assess the incidence and risk factors for “recurrent” CIN2/3 after LEEP among HIV- infected women.
2. To determine baseline HR-HPV types (in tissue) among HIV-infected women with CIN2/3 undergoing LEEP compared to the HR-HPV types with “recurrent” cervical lesions after a second LEEP.
3. To determine the immunohistochemical differences between the initial and repeat LEEP specimens among HIV-infected women with “recurrent” CIN2/3

 Uganda 2021-01-27 2024-01-27 Medical and Health Sciences Non-degree Award
Edward Nsubuga
ID:
Work place violence and interventions used at mental health units in uganda
REFNo: HS435ES

Identifying the patterns of workplace violence,contributing factors ,and remedial interventions available in place for such victims.
 Uganda 2021-01-25 2024-01-25 Medical and Health Sciences Non-degree Award
Joseph Kagaayi
ID: UNCST-2024-R015946
 Hard to reach populations in Uganda; An observational cohort study
REFNo: HS607ES

Aim 1-We will first determine CHP coverage and HIV incidence among hard-to-reach persons using enhanced surveillance techniques.

Aim 2-We will then characterize ongoing sources of incident HIV infection through partner tracing of newly HIV-infected participants and matched HIV-negative controls, viral phylogenetics, and sexual network analyses.

Aim 3-Finally, we will determine if state-of-the-art CHP can engage hard-to-reach populations and reduce population-level HIV incidence to a level sufficient for HIV elimination by 2030.



Uganda 2021-01-25 2024-01-25 Medical and Health Sciences Non-degree Award
Pauline Byakika-Kibwika
ID: UNCST-2019-R001206
 Evaluation of impact of National Research Information Management System on the research regulatory process in Uganda
REFNo: HS906ES

The general objective of this proposal is to determine the usage of NRIMS as well as evaluate the experiences and attitudes of users of the systems at Makerere University, Mulago Hospital and UCI RECs.
2.1.1 Primary Objective
1. To determine the turnaround time between submission of protocols to review and approval, and time to receipt of feedback from REC for one year before and one year after roll out of NRIMS for RECs in Makerere Hospital Complex and UCI
2.1.2 Secondary Objectives
1. To qualitatively document and compare stakeholders’ experiences regarding use of the paper based and the NRIMS for research protocol review and approval in Makerere University, Mulago Hospital complex and UCI at start of roll out and one year after of roll out.
Uganda 2021-01-25 2024-01-25 Medical and Health Sciences Non-degree Award
RACHEAL ALINAITWE
ID: UNCST-2020-R014509
 The feasibility of involving Village Health Team Members in identifying and referring older persons with cognitive impairment in Wakiso District, Uganda.
REFNo: HS988ES

1. To assess the feasibility of involving Village Health Team Members in identifying older persons with cognitive impairment in Wakiso district, Uganda.
2. To assess the feasibility of involving Village Health Team members in referring older persons with cognitive impairment to health centre III for care in Wakiso district, Uganda.

 Uganda 2021-01-25 2024-01-25 Medical and Health Sciences Non-degree Award
Juliana Namutundu
ID:
DEVELOPMENT AND VALIDATION OF A CERVICAL CANCER RISK SCORING SYSTEM FOR PREDICTING CERVICAL CANCER AMONG UGANDAN WOMEN AGED 25-49 YEARS
REFNo: HS1043ES

1) To develop a cervical cancer risk scoring system for Ugandan women based on major sexual, behavioral, and reproductive risk factors.
2) To validate a cervical cancer risk scoring system for Ugandan women based on major sexual, behavioral, and reproductive risk factors.

 Uganda 2021-01-25 2024-01-25 Medical and Health Sciences Non-degree Award
Patrick Tumusiime Kagurusi
ID:
Documenting lived experiences of youth in Sub Saharan Africa during the covid-19 pandemic: implications for policy and program considerations
REFNo: SS650ES

General Objective
To document the lived experiences of youth in Sub Saharan Africa and programmatic considerations for their health and well-being in the wake of the COVID-19 pandemic.
Specific Objectives:
1. To document the lived experiences of the youth in Sub Saharan Africa across health and socio-economic tiers during the COVID-19 pandemic
2. To document coping strategies by the youth on health and socio-economic effects during the COVID-19 pandemic
3. To assess how the coping strategies employed help youth navigate the health and socio-economic effects of the pandemic.
4. To document recommendations that can mitigate health and socio-economic effects of the pandemic for future policies and programmes targeting the youth
 Uganda 2021-01-25 2024-01-25 Social Science and Humanities Non-degree Award
GRACE NAMBATYA KYEYUNE
ID:
A Phase IIa randomized double-blind, placebo-controlled clinical trial to determine the preliminary safety and efficacy of UBV-01N in adult patients infected with SARS-COV-2 (COVID-19) in Kampala, Uganda.
REFNo: HS1207ES

a) To evaluate the preliminary safety and of UBV-01N, in adult patients diagnosed with COVID-19 and treated with UBV-01N
b) To assess the preliminary efficacy of UBV-01N + standard of care, compared to UBV-01N placebo + standard of care, in adult patients diagnosed with COVID-19, in Kampala, Uganda.

 Uganda 2021-01-25 2024-01-25 Medical and Health Sciences Non-degree Award
Ruth Namazzi
ID: UNCST-2020-R014305
 Health-related Quality of Life (HRQoL) of Ugandan children with Sickle Cell Disease (SCD): A comparative study of HRQoL outcomes in the Zinc for Infection Prevention (ZIPS) trial and at the Nalufenya Sickle Cell Clinic (NSCC)
REFNo: HS1069ES

This proposal is designed as a sub-study nested within the ‘Zinc for Infection Prevention in Sickle cell anemia (ZIPS) trial, and has 3 specific aims –

Aim 1: To determine, using a SCD-specific testing instrument, if HRQoL outcomes of children with SCD enrolled in a clinical trial (ZIPS) differ from children with SCD who receive standard of care at the Nalufenya Sickle Cell Clinic (NSCC) in Jinja, Uganda

Aim 2: To determine, using an SCD-specific testing instrument, if HRQoL of children with SCD in the ZIPS study differs between those on zinc supplementation vs. those on placebo

Aim 3: To document caregiver perceptions regarding factors influencing HRQoL of children with SCD in the ZIPS study (those on zinc supplementation vs. those on placebo) and those receiving standard of care at the Nalufenya Sickle Cell Clinic (NSCC) in Jinja, Uganda

 Uganda 2021-01-25 2024-01-25 Medical and Health Sciences Non-degree Award
Christine  Wiltshire Sekaggya
ID: UNCST-2019-R000578
 Evaluating the effect of private provider engagement on access to TB screening and diagnostic services in two large urban districts in Uganda: an observational study.
REFNo: HS1106ES

The overall aim of this study is to determine the effect of private health providers on access to TB diagnostic services in two large urban cities in Uganda.

The primary objective will be to:
1. To examine the effect of community pharmacies’ engagement on a) time to TB treatment and b) costs incurred while seeking care for TB by patients with bacteriologically confirmed TB in the PRES project in Kampala and Wakiso

The secondary objectives will be to
2. To understand community pharmacies’ perspectives towards provision of TB screening services and linkage to treatment.
3. To identity other infectious causes of cough among patients who are screened for TB at community pharmacies

 Uganda 2021-01-25 2024-01-25 Medical and Health Sciences Non-degree Award
JUSTINE NAMWAGALA MUKOSE
ID:
Explorative investigation of the burden and risk factors of uvula infections and associated traditional uvulectomy practices in Luwero district and surrounding areas
REFNo: HS1167ES

OBJECTIVES


The overarching objective of this explorative research study is to investigate and document, in a scientifically sound manner, the condition called “akamiro”; determine the case definition, describe its general epidemiology including the beliefs and perceptions around it and the traditional surgical procedure, and commence etiological investigations.


Our proposed specific objectives are;

1. To determine the clinical case definition of the uvula infections called “akamiro” – general and age-specific case definitions for infants, children, adolescents and adults.
2. To investigate major risk factors of uvula infections /“akamiro”.
3. To determine the magnitude and associated factors of uvula infections /“akamiro”, and geo-map its spread.
4. To determine the prevalence of traditional uvulectomy and its outcomes and sequelae.

5. To establish the community beliefs, perceptions and practices associated with “akamiro”.

 Uganda 2021-01-25 2024-01-25 Medical and Health Sciences Non-degree Award
Munshi Sulaiman
ID:
Women’s Leadership in Village Savings and Loan Associations (VSLAs) in Uganda
REFNo: SS685ES

The research has two key objectives. The first is to understand the current starus and barriers of women to take leadership roles in VSLA committees. The second objective is to identify possible interventions that can strengthen their leadership roles.
Bangladesh 2021-01-25 2024-01-25 Social Science and Humanities Non-degree Award
Janet SEELEY
ID:
The direct and indirect effects of HIV/AIDS on the Health and wellbeing of older people. Wave 5 Study protocol
REFNo: SS696ES

The aim of the study is to describe longitudinally the survival, health and wellbeing of older people who are directly and indirectly affected by HIV and AIDS, with special attention to the effects of the introduction of ART. In addition, we aim to investigate the impact of the COVID-19 pandemic on health and wellbeing of WOPS participants

Specific objectives

1. To describe the effects of HIV and HIV treatment on the (physical and mental) health and wellbeing of older people
2. To determine the effects of HIV in older people especially older women on their social situation, with special focus on care giving.
3. Document some of the biomarkers associated with chronic inflammation and immune function in the ageing process
4. To document the causes and risk factors for mortality among older people with and without HIV in Uganda.
5. To document the patterns of multimorbidity in older people with and without HIV in Uganda
6. Investigate the impact of the COVID-19 pandemic and the lockdown on the WOPS participants


 UK 2021-01-25 2024-01-25 Social Science and Humanities Non-degree Award
Gloria Nakato Valentine
ID:
Developing and deploying aflatoxin biological control products for integrated aflatoxin management in Uganda and making it accessible through private sector engagement
REFNo: A114ES

Obj. 1: Develop, validate, and register at least one biocontrol product (Aflasafe) for aflatoxin management in maize, sorghum and groundnut.
Obj. 2: Create awareness among stakeholders (e.g., farmers, traders, consumers) along the maize, sorghum, and groundnut value chains of the health and trade impacts of aflatoxins, and to improve knowledge and use of strategies for mitigating aflatoxin that are centered on pre-harvest use of biocontrol products, best agricultural and post-harvest management practices.
Obj. 3: Develop and implement a strategy for commercializing Aflasafe to ensure wide distribution and availability to stakeholders through private sector engagement.

 2021-01-25 2024-01-25 Agricultural Sciences Non-degree Award
Denis Muhangi
ID: UNCST-2020-R014258
 Social – Behavioral / Anthropological Study on COVID-19 in Uganda
REFNo: SS700ES

The overall objective of this anthropological study is to generate evidence-based insights on why people behave the way they do in response to COVID-19 and the recommended preventive measures; and to provide recommendations on potential approaches that are culturally and socially acceptable that can be applied to improve compliance and enhance adoption of sustainable behavior change across different groups and the general public in Uganda.

The specific Objectives are:

To assess the extent and how different sections of the population adhere to / comply with the set of desired behaviors / practices as recommended by Government.

To establish trends in behaviour change since the beginning of the COVID-19 crisis.

To establish why people behave the way they do, taking into account the different target groups (individual or group), differences in culture and the immediate context (social economic and structural factors).

To assess the changing community dynamics and the effect of the COVID-19 measures on individual and communal norms that have a bearing on COVID-19 transmission such as - mass gatherings in school set-ups, religious, social and cultural congregations e.g., entertainment, weddings and burial practices.

To establish what each target group thinks would be the prerequisites to protect themselves from COVID-19.

To identify potential culturally and socially acceptable approaches/solutions to health problems which can be applied to improve compliance and enhance adoption of sustainable behavior change - across different groups.
 Uganda 2021-01-25 2024-01-25 Social Science and Humanities Non-degree Award
Innocent Besigye Kabahena
ID: UNCST-2019-R001025
 Evaluating the use of the primary care assessment tool to improve primary care performance in Tororo District, Uganda
REFNo: HS1174ES

1. To adapt and validate the patients'. managers' and health care providers' primary care assessment tools.
2. To measure primary care performance using adapted and validated PCAT tools.
3. To evaluate the implementation of the designed intervention to improve primary care performance.
 Uganda 2021-01-25 2024-01-25 Medical and Health Sciences Degree Award
Eddy Walakira Joshua
ID: UNCST-2022-R009077
 Uganda Commercial Sex Exploitation of Children
REFNo: SS724ES

1) Estimate the prevalence of children at of, and engaged in commercial sex exploitation in Karamoja

2) Estimate the proportion of children in Kampala involved in commercial sex exploitation

3) Measure Knowledge, attitudes and practices around CSEC in Karamoja
 Uganda 2021-01-25 2024-01-25 Social Science and Humanities Non-degree Award
Evelyn Avalos
ID:
The impact of protracted refugee displacement and disrupted intergenerational relations on the secure and healthy futures of older people in Uganda
REFNo: SS462ES

-To identify later-life forcibly displaced survival strategies/sustainable livelihoods in a context of family separation
- To understand who covers the needs of aged refugees and to what extent they are covered. Specifically when family relationships and State's social security are disrupted
- To explain the role of place in shaping lives and ageing experiences of aged refugees
-To discover how later-life identities and attachments could be shaped at different social and spatial scales
 El Salvador 2021-01-22 2024-01-22 Social Science and Humanities Non-Clinical Trial Degree Award
Sona Shah
ID:
Adoption of a wireless vital sign monitor for observation of COVID-19 patients
REFNo: HS733ES

1. To evaluate the feasibility of a wireless vital sign monitor for use on critical patients in COVID-19 treatment facilities
2. To assess the accuracy of a wireless vital sign monitor (neoGuard) on adult patients
 USA 2021-01-22 2024-01-22 Medical and Health Sciences Non-degree Award
Christine Nalwadda Kayemba
ID: UNCST-2020-R014220
 Understanding Leadership and Accountability mechanisms in delivering a responsive Maternal and Newborn care in a decentralized health system, Uganda: Lessons for SRHS improvement
REFNo: HS1024ES

Broad objective:

The main objective of this study is to assess leadership and accountability mechanisms for maternal and newborn health in decentralized health systems in Uganda in order to formulate a theory of change for delivering an efficient health services for maternal and newborn health


Specific Objective:

1.Review existing health systems policies in order to highlight leadership and accountability guidelines/policies for maternal and newborn health
2.Explore health systems managers’ understanding and interpretation of leadership and accountability guidelines/policy directives for maternal and newborn health
3.Describe how decentralized health systems managers adapt and implement leadership and accountability policies in maternal and newborn health

 Uganda 2021-01-22 2024-01-22 Medical and Health Sciences Non-degree Award
Warren Phipps
ID:
Attitudes and Practices of Antimicrobial Resistance and Stewardship at the Uganda Cancer Institute
REFNo: HS871ES

We will investigate the knowledge, attitudes, and practices about antimicrobial use and antimicrobial resistance among the doctors (including medical officers, fellows, oncologists, and surgeons), nurses, and pharmacists at the Uganda Cancer Institute (UCI).

The aims of the study are;
Aim 1: To examine the current knowledge and attitudes of UCI healthcare providers towards antimicrobial resistance.
Aim 2: To determine the current knowledge and attitudes of UCI healthcare providers towards antimicrobial stewardship.
Aim 3: To understand perceived barriers to the diagnosis and management of infections in patients at UCI

USA 2021-01-22 2024-01-22 Medical and Health Sciences Non-degree Award
Jennifer Serwanga
ID: UNCST-2024-R002056
 Characterising the Global Immune Response to SARS-CoV-2 in COVID-19 Acutely Infected and Recovered Ugandans
REFNo: HS997ES

To describe the frequencies and phenotypes of SARS-CoV2 induced immune
responses in qrt-PCR COVID-19 confirmed Ugandan cases.
b) To describe the evolution and durability of the induced responses.
c) To describe factors associated with COVID-19 disease outcome.
d) To isolate and clone SARS-CoV-2 spike specific human monoclonal antibodies with
potent virus neutralising capabilities
 Uganda 2021-01-22 2024-01-22 Medical and Health Sciences Non-degree Award
David Musoke
ID:
A feasibility study for a randomised controlled trial on integrated malaria prevention in Wakiso district, Uganda
REFNo: HS999ES

1. To explore community willingness to participate in an RCT on integrated malaria prevention.
2. To assess stakeholder perspectives on the RCT on integrated malaria prevention.

Uganda 2021-01-22 2024-01-22 Medical and Health Sciences Non-degree Award
David Musoke
ID:
Use of Photovoice to explore community members perspectives on health and healthcare challenges in Mukono District, Uganda
REFNo: HS1058ES

To use photovoice as a community-based participatory research method to explore healthcare delivery including barriers and challenges in Mukono district so as to provide information to inform future research and interventions to improve health of the community.
Uganda 2021-01-22 2024-01-22 Medical and Health Sciences Non-degree Award
ALEX NDYABAKIRA
ID:
Durability monitoring of Long Lasting Insecticidal Nets in Uganda, distributed during the 2020 mass campaign
REFNo: HS1109ES

Primary objective
1.To assess the physical durability of 5 different brands of nets over a three-year period, estimate median LLIN survival and identify major determinants of field performance
Secondary objectives
1. To describe major behavioral aspects of net care and repair and their impact on physical durability
2. To assess the insecticidal effectiveness (bio-efficacy) and chemical residue of 5 ITN brands during three years of field use

 Uganda 2021-01-22 2024-01-22 Medical and Health Sciences Non-degree Award
Philippa Musoke
ID: UNCST-2021-R013523
 Clinical manifestations and Outcomes of SARS-CoV-2 Infection in pregnancy in Africa: Novel Insights from the Democratic Republic of the Congo, Ghana, Kenya, Nigeria, South Africa and Uganda (AFRE-Mom-CoV-19) protocol
REFNo: HS1164ES

To retrospectively investigate the socio-demographic and clinical characteristics and maternal/infant outcomes of pregnant patients with RT-PCR-confirmed SARS‐CoV‐2 infection in six west, east, central and southern African countries: DRC, Ghana, Kenya, Nigeria, South Africa and Uganda.
Uganda 2021-01-22 2024-01-22 Medical and Health Sciences Non-degree Award
Amon Nuwahereza
ID: UNCST-2022-R011428
 Ride and Arrive Safe (RAS). A Case study of Mbarara Municipality
REFNo: HS577ES

i. To explore the feasibility of the community facilitation and engagement approach in equipping the Boda-boda cyclists with safety riding knowledge and skills.
ii. To develop a Boda-boda safety user check the mobile application for passengers using Boda-boda a means of transport
iii. To evaluate the effect of Boda-boda cyclist training and community engagement in reducing the number of Boda-boda road traffic accident-related admissions at Mbarara Regional Referral Hospital.

 Uganda 2021-01-21 2024-01-21 Medical and Health Sciences Non-degree Award
Denis  Bwayo
ID:
Program Assessment and Implementation Learning for the University Research Co., LLC - Department of Defense HIV Prevention Program – Uganda
REFNo: HS959ES

1.To determine compliance to program set targets for the URC-DHAPP program between October 2018 and September 2021
2.To assess the quality of HIV services delivered at 28 UPDF HIV clinics
3.To determine program outcomes across key program implementation strands in line with 95:95:95 frameworks
4.To share implementation experiences across key program implementation strands including HIV testing, ART services, TB diagnosis and management, PMTCT, OVC and systems strengthening.

 Uganda 2021-01-21 2024-01-21 Medical and Health Sciences Non-degree Award
Kamya Moses
ID: UNCST-2020-R014203
 ENHANCED ENTOMOLOGICAL SURVEILLANCE(EES) TO INFORM MALARIA CONTROL IN UGANDA
REFNo: HS1059ES

1. To examine the impact of current vector control interventions on malaria vector densities, vector behaviour, and species composition.
2. To monitor the status and intensity of insecticide resistance.
3. To establish the entomological inoculation rates in the selected districts.
4. To build the capacity of districts to conduct routine entomological surveillance

 Uganda 2021-01-21 2024-01-21 Medical and Health Sciences Non-degree Award
Philippa Musoke
ID: UNCST-2021-R013523
 Manifestations and Outcomes of Hospitalized African children and Adolescents with SARS-CoV-2 Infection: Insights from the Democratic Republic of the Congo, Ghana, Kenya, Nigeria, South Africa and Uganda (AFRE-Ped-CoV-19) protocol Version November 06 2020. Grant No. 1R25TW011217-01
REFNo: HS1168ES

Study Aims

a) To describe the socio-demographic features; clinical WHO COVID-19 staging at admission, clinical characteristics, laboratory features including inflammatory and
cardiac markers; imaging investigations and associated abnormalities, treatments applied; and comparisons within and across participating African countries.
b) To estimate the prevalence of comorbidities at presentation and recent/current treatment with immunosuppressive drugs and comparisons within and across
participating African countries.
c) To estimate the prevalence of associated tuberculosis (past, current), HIV status (HIV-exposed uninfected or HIV-infected, and type of treatment if HIV-infected), malaria, bacterial infections influenza and other viral infections and comparisons within and
across participating African countries.
d) To assess overall mortality and independent factors associated with mortality and comparisons within and across participating African countries.

 Uganda 2021-01-21 2024-01-21 Medical and Health Sciences Non-degree Award
Grace Ndeezi
ID: UNCST-2019-R001802
 A Phase 2b Study to Evaluate the Safety and Efficacy of IMR-687 in Subjects with Sickle Cell Disease IMR-SCD-301
REFNo: HS1130ES

Primary Objectives
To evaluate the HbF response to IMR-687 versus placebo
To evaluate the safety of IMR-687 versus placebo
Secondary Efficacy Objectives
To evaluate the effect of IMR-687 versus placebo on HbF-associated biomarkers
To evaluate the effect of IMR-687 versus placebo on indices of red cell hemolysis
To evaluate the effect of IMR-687 versus placebo on indices of WBC adhesion
To evaluate the effect of IMR-687 versus placebo on the incidence of VOCs
To evaluate the effect of IMR-687 versus placebo on quality of life (QoL) measures

Pharmacokinetic Objectives
To evaluate the PK of IMR-687 and any major circulating metabolites
Exploratory Efficacy Objectives
To evaluate the effect of IMR-687 versus placebo on changes in RBC characteristics and total Hb
To evaluate the effect of IMR-687 versus placebo on renal function
To evaluate the effect of IMR-687 versus placebo on indices associated with cardiovascular pathophysiology and ischemic stroke risk

Uganda 2021-01-21 2024-01-21 Medical and Health Sciences Non-degree Award
FRED SEMITALA COLLINS
ID: UNCST-2020-R014096
 Strengthening Integrated Screening for TB and COVID19 in Kampala, Uganda
REFNo: HS1152ES

The overall goal is to establish the acceptability, feasibility and potential for scaling up the use of COVID19-TB Screening algorithm at Kiruddu National Referral Hospital.
Specific objectives

(1) To explore the perspectives of healthcare providers on the integration of COVID19 and TB screening at Kiruddu National referral Hospital.
(2) To determine the effect of the COVID19-TB algorithm on the proportion of patients screened for TB at Kiruddu National Referral Hospital over a 4-month period.

 Uganda 2021-01-21 2024-01-21 Medical and Health Sciences Non-degree Award
Kirsten Beyer M
ID: UNCST-2021-R013472
 Assessing Health Professionals’ Knowledge, Perspectives and Practices Regarding HPV and Cervical Cancer Prevention and Control among Women Living with Human Immunodeficiency Virus Infection in Uganda
REFNo: HS782ES

General Objective The proposed study seeks to examine the role that health professionals play in influencing WHIVs’ perceptions of HPV and cervical cancer and their associated health behaviors in Uganda.

Specific Objective
Interview public health and health care professionals (including clinicians, nurses, counselors, other/public health professionals, and community health workers/village health teams) to examine the following:
1. Knowledge regarding how HPV or cervical cancer impacts WHIV, which populations are impacted most, and frequency of HPV vaccination, screening and treatment. 2. Perspectives regarding barriers/facilitators of cervical cancer and HPV prevention and treatment among WHIV. 3. Practices regarding HIV professionals’ work in cervical cancer and HPV.
USA 2021-01-20 2024-01-20 Medical and Health Sciences Non-degree Award
Emmanuel Sendaula
ID: UNCST-2020-R014767
 Clinical profile of HIV-infected patients receiving a holistic approach of care model attending Reach Out Mbuya facilities in Kampala district
REFNo: HS903ES

Main Objective

To describe the clinical profile and the factors associated with viral suppression status among HIV-infected patients receiving a holistic approach of care model in Kampala District.
Specific objectives

1. To describe the clinical profile of HIV-infected patients receiving a holistic model of care in Kampala District.
2. To determine the socio-demographic factors associated with viral suppression status among HIV-infected patients receiving a holistic model of care in Kampala District.
3. To determine the clinical factors associated with viral suppression status among HIV-infected patients receiving a holistic model of care in Kampala District.

 Uganda 2021-01-20 2024-01-20 Medical and Health Sciences Non-degree Award
FRANK MULINDWA
ID:
Glucose metabolism changes in HIV patients starting dolutegravir based antiretroviral treatment in Uganda
REFNo: HS1032ES

1) To determine the incidence and predictors of diabetes at week 48 in Ugandan HIV patients initiating dolutegravir.
2) To describe temporal changes in insulin resistance, pancreatic beta cell function, body mass index and blood glucose in Ugandan HIV patients on dolutegravir for 48 weeks.
3) To determine the effect of DTG on intracellular magnesium levels in Ugandan HIV patients on dolutegravir for 48 weeks.
4) To compare insulin kinetics in patients who develop diabetes while on dolutegravir and those that don’t in Ugandan HIV patients.
5) To determine the difference in DTG pharmacokinetics in HIV positive patients with incident hyperglycemia and those without in Ugandan HIV patients.

 Uganda 2021-01-20 2024-01-20 Medical and Health Sciences Non-degree Award
Proscovia Nabunya
ID: UNCST-2019-R000970
 SAY NO TO STIGMA”: Making Mental Health Visible Among School-Going Children in Rural Uganda
REFNo: SS637ES

The objective of this proposed study is to develop a set of new age-appropriate, culturally relevant signage and messaging around mental health and stigma for this study. The visual solutions will be developed through a set of extensive hands-on creative workshops and focus groups with children as well as school administrators and teachers working in one primary school in the Masaka region of Uganda. After visual and message development, the visuals will be presented to a different group of students within the school to gather feedback on their effectiveness and clarity in portraying mental health and stigma.
 Uganda 2021-01-20 2024-01-20 Social Science and Humanities Non-degree Award
Polycarp Komakech
ID:
Incentivizing Action to Reduce Air Pollution and Susceptibility to COVID-19
REFNo: SS667ES

The main objective is to investigate a number of practical and scalable strategies to reduce waste burning through voluntary behavioral change and thereby reduce the exposure of residents to harmful air pollution. The specific objectives are (a) to investigate whether the provision of information about the link between air pollution and the chances of contracting and dying from COVID-19 can spur action to stop waste burning, (b) to test the efficacy of a novel design where social competition that is not imposed top-down but is organized horizontally can help leaders to organize communities for positive action towards reducing waste burning.
Uganda 2021-01-20 2024-01-20 Social Science and Humanities Non-degree Award
SHAFIC MAKUMBI
ID:
Voluntary Consent to Research on Children: A sub-study of the CHAPAS-4 and ODYSSEY Trial
REFNo: SS677ES

1.2 Overall objective
The aim of this study is to assess parental perception of voluntariness of consent in Paediatric HIV clinical trials and associated factors.

1.4 Specific objectives
1.4.1. To describe the process in which parents and guardians consent for their children to be enrolled in two pediatric HIV Clinical Trials.
1.4.2. To measure the level of perceived voluntariness of consent using the voluntariness ladder
1.4.3. To identify the social demographic, situational and external control factors that influence parental perception of the voluntariness of their consent

 Uganda 2021-01-20 2024-01-20 Social Science and Humanities Degree Award
Rhoda Wanyenze
ID: UNCST-2021-R013352
 Impact of Masks on Community Spread of COVID-19: Evidence from Uganda
REFNo: HS1124ES

2.1 General Objective

The aim of this study is to provide policy makers with the first population-based estimate of the extent to which face coverings reduce the spread of SARS-CoV-2. We also intend to provide evidence to the Ministry of Health in Uganda (and public health officials more generally) with evidence about effective communication and education tools for increasing the proper use of masks in the general population.


2.2 Specific Aims

The specific objectives of our study are as follows:

Aim 1: To test whether free mask distribution increases the proper use of masks in intervention communities
Aim 2: To test whether combining free mask distribution with education and communication about masks and COVID-19 increases the proper use of masks in intervention communities Aim 3: To evaluate whether increased mask use affects seroprevalence of SARS-CoV-2
Aim 4: To evaluate potential spillovers, or whether higher mask use in intervention communities affect mask use and probability of infection in neighboring non-intervention communities

 Uganda 2021-01-20 2024-01-20 Medical and Health Sciences Non-degree Award
Kamya Moses
ID: UNCST-2020-R014203
 COVID-19 sydromic and sero-surveillance using established Uganda malaria surveillance sites.
REFNo: HS1125ES

To establish COVID-19 syndromic surveillance through existing Uganda Malaria Surveillance sites by collecting additional data on COVID-19 specific symptoms.

To perform enhanced surveillance for COVID-19 and assess for serological evidence of past infection with SARS-CoV-2 in patients, in order to estimate disease burden and map the geographic spread of the epidemic.

 Uganda 2021-01-20 2024-01-20 Medical and Health Sciences Non-degree Award
Edgar Agaba
ID:
One Nutrition in Complex Environments (ONCE), a cluster-randomized trial of nutrition education and access to simple supportive technologies in improving agricultural practices and water quality management
REFNo: HS492ES

Aim 1: Implement and test a social and behavior change (NIPP) program alone (free-standing) and in combination with a “value-added” approach (NIPP+). The latter includes access to innovative low-cost tools and technologies relating to WASH and agriculture.

Aim 2: Identify best-practices emerging from the implementation of both approaches through process and program monitoring for effective integration, implementation, scale-up, and uptake of multi-sectoral and multi-level packages in complex environments to ascertain potential for scale up.

Aim 3: Study the sustained impact of the NIPP approach and the “value added” package (NIPP+) on knowledge and practices by gender within participating households, environmental risk factors, child health and nutritional status through a rigorous impact evaluation and longitudinal monitoring system.
 Uganda 2021-01-12 2024-01-12 Medical and Health Sciences Non-degree Award
Henry Ddungu
ID: UNCST-2019-R000966
 A Phase 2b Study to Evaluate the Safety and Efficacy of IMR-687 in Subjects with Sickle Cell Disease.
REFNo: HS1078ES

Primary Objectives:
(a)To evaluate the fetal hemoglobin (HbF) response to IMR-687 versus placebo
(b)To evaluate the safety of IMR-687 versus placebo.
Secondary Efficacy Objectives
(a)To evaluate the effect of IMR-687 versus placebo on HbF-associated biomarkers
(b)To evaluate the effect of IMR-687 versus placebo on indices of red cell hemolysis
(c)To evaluate the effect of IMR-687 versus placebo on indices of white blood cell (WBC)
adhesion
(d)To evaluate the effect of IMR-687 versus placebo on the incidence of vaso-occlusive crises(VOCs)
(e)To evaluate the effect of IMR-687 versus placebo on quality of life measures

Pharmacokinetic Objectives
(i)To evaluate the PK of IMR-687 and any major circulating metabolites

Exploratory Efficacy Objectives
(ii)To evaluate the effect of IMR-687 versus placebo on changes in red blood cell (RBC)
characteristics and total Hb
(iii)To evaluate the effect of IMR-687 versus placebo on renal function
(iv)To evaluate the effect of IMR-687 versus placebo on indices associated with
cardiovascular pathophysiology and ischemic stroke risk.
 Uganda 2021-01-12 2024-01-12 Medical and Health Sciences Non-degree Award
Kamya Moses
ID: UNCST-2020-R014203
 Impact of long-lasting insecticidal nets (LLINs) treated with pyrethroid plus pyriproxyfen vs LLINs treated with pyrethroid plus piperonyl butoxide on malaria incidence in Uganda: a cluster-randomised trial
REFNo: HS1097ES

Primary Objective:
To evaluate the impact of LLINs treated with a pyrethroid insecticide plus pyriproxyfen (PPF LLINs), as compared to LLINs treated with a pyrethroid plus piperonyl butoxide (PBO LLINs), on malaria incidence in Uganda. We will test the hypothesis that malaria incidence will be lower in intervention clusters (randomised to receive PPF LLINs) than in control clusters (randomised to receive PBO LLINs).

Secondary Objectives:
To evaluate the impact of PPF LLINs vs PBO LLINs on parasite prevalence, anaemia, and vector density.
To estimate the cost-effectiveness of delivering PPF LLINs, as compared to PBO LLINs
To assess net durability, survivorship and use of PPF LLINs vs PBO LLINs.

Uganda 2021-01-11 2024-01-11 Medical and Health Sciences Non-degree Award
Robert Opika Opoka
ID: UNCST-2021-R014036
 The Influence of Comprehensive Follow-Up in Pediatric Sickle Cell Disease in an African Setting: a retrospective cohort Study
REFNo: HS636ES

General Objectives: To compare a set of sickle cell-related outcomes (mortality, stroke, blood transfusions, and hospitalizations) between children with SCA on a comprehensive follow up schedule under clinical trials setting and that of a cohort of children with SCA receiving routine care at a specialized sickle cell clinic.


Primary Objective: To compare sickle cell-related outcomes in the NOHARM children who were on the placebo arm to those of children of similar age group from the MHSCC who fulfilled the inclusion criteria for the NOHARM study at the time the study was recruiting patients but who were not enrolled.

Secondary Objectives: To assess the added effect of hydroxyurea therapy (in addition to comprehensive follow up schedule) on sickle cell-related outcomes. This shall be done by comparing sickle cell related outcomes in
1) NOHARM children randomized to hydroxyurea arm and that of the cohort of non-study MHSCC children with SCA over the time period of the NOHARM study (calendar years 2015-17).
2) NOHARM children on the MTD dose of hydroxyurea to that of the cohort of non-study MHSCC children with SCA over the time period of the MTD study (calendar years 2018-19).

 Uganda 2021-01-08 2024-01-08 Medical and Health Sciences Non-degree Award
JANE  BWIRUKA FRIDA
ID:
Student teachers Narratives on Pedagogical Practices that inform their Competences at Makerere University, Uganda
REFNo: SS518ES

1)Explore the narratives of student teachers on teaching practices that inform their competences at Makerere University.
2)Explore the narratives of student teachers on mentoring practices that inform their competences at Makerere University.
3)Explore the narratives of student teachers on supervision practices that inform their competences at Makerere University.
 Uganda 2021-01-08 2024-01-08 Social Science and Humanities Degree Award
ANNETTEE NAKIMULI OLIVIA
ID: UNCST-2022-R011194
 Using new genomic approaches to investigate causes of maternal sepsis among women delivering in sub-Saharan Africa
REFNo: HS969ES

Primary objectives
1)To compare the pathogen profiles using routine microbiology (blood cultures, urinalysis, malaria tests, complete blood count) among women with fever at delivery and those without fever at KNRH
2)To compare the prevalence of Streptococcus agalactiae in placental samples using qPCR among women with fever at delivery and those without fever at KNRH

Secondary objectives
1)To compare the composition and diversity of the nasal and ano-vaginal microbiota among women with fever at delivery and those without fever at KNRH
2)To compare the composition and diversity of the nasal and ano-vaginal microbiota among newborns of women with fever at delivery and the newborns of those without fever at KNRH
3)To compare the single-cell RNA-seq transcriptome of the placentae of women with placental malaria and those without placental malaria at Kawempe National Referral Hospital (KNRH).


 Uganda 2021-01-08 2024-01-08 Medical and Health Sciences Non-degree Award
Moreen Kiiza
ID:
The Right to Rehabilitation for the Survivors of Torture: A Case Study of Urban Refugees in Katwe-Kinyolo, Kampala-Uganda
REFNo: SS630ES

1. To assess the adequacy of the legal and policy framework governing rehabilitation for refugee survivors of torture in Uganda.
2. To ascertain the rehabilitation needs of refugee survivors of torture in Uganda.
3. To establish the adequacy of available mechanisms for the rehabilitation of refugee survivors of torture in Uganda.
4. To establish the challenges to the rehabilitation of refugee survivors of torture in Uganda.

 Uganda 2021-01-08 2024-01-08 Social Science and Humanities Degree Award
VICTOR BEWAYO
ID: UNCST-2024-R003092
 ASSESSMENT OF THE LEVEL OF REPORTING ADVERSE DRUG REACTIONS AND ASSOCIATED FACTORS AMONG HEALTH CARE PROFESSIONALS IN COMMUNITY PHARMACY PRACTICE IN KAMPALA CITY, UGANDA
REFNo: HS956ES

1. To establish the proportion of community pharmacy staff that have reported an ADR in the past one year in Kampala City
2. To identify the factors associated with ADR reporting among community pharmacy staff in Kampala City

 Uganda 2021-01-07 2024-01-07 Medical and Health Sciences Degree Award
Erica Harrison
ID:
COVID-19 VACCINE UPTAKE STUDY IN UGANDA
REFNo: SS661ES

Research Questions
What is the public’s knowledge, attitude and perceptions towards COVID-19 vaccine in Africa?
Is there an association between the public perception of COVID-19 vaccine and background vaccine confidence and hesitancy levels.

Specific Objectives
Examine the public’s knowledge of COVID-19 and a future COVID-19 vaccine.
Assess the public’s background vaccine confidence and hesitancy levels.
Assess the public’s perceived risks/benefits of a future COVID-19 vaccine.
Determine the willingness of the public to accept and or recommend a future COVID-19 vaccine.
Examine the influence of the knowledge and perceptions of COVID-19 vaccine on the expected uptake of a potential vaccine.
Examine the public’s handling of COVID-19 related rumors.

 UK 2021-01-07 2024-01-07 Social Science and Humanities Non-degree Award
Mariam Namasaba
ID:
A school-based resilience training program for caretakers of children with disabilities in Uganda: a cluster-randomized controlled study
REFNo: HS1027ES

To examine the impact of a resilience training program on the mental well-being and coping strategies of caretakers of CWDs in schools in Uganda.

To assess the impact of a resilience training program on the sense of self-efficacy of school caretakers of CWDs in schools in Uganda.
 Uganda 2021-01-06 2024-01-06 Medical and Health Sciences Degree Award
Yvonne Mugerwa Kidza Kitego
ID:
The Kampala Slum Maternal Newborn (MaNe) Project - Innovating for Better Referral Systems: an implementation research protocol
REFNo: HS962ES

• To harness the public and private facility mix to provide quality and affordable maternal and newborn care services to the urban poor.
• To strengthen referral linkages between public and private health facilities for MNH care.
• To educate mothers, caretakers of newborns and spouses about appropriate actions on what MNH services to seek and from where
 Uganda 2021-01-06 2024-01-06 Medical and Health Sciences Non-degree Award
NORAH IKINYOM
ID:
THE POTENTIAL OF NUTRI-MEDICINAL PLANTS IN THE MANAGEMENT OF OPPORTUNISTIC INFECTIONS ASSOCIATED WITH HIV/AIDS
REFNo: HS983ES

(a)To determine availability of Nutri-medicinal plant species in Acholi sub region and understand traditional methods and formulations being used in quality assurance of nutri-medicinal plant preparations by Traditional medicine practitioners
(b) to determine chemical composition and nutritional characteristics of nutri-medicinal plants, to be conducted according to good laboratory practices (GLPs)
(c) To evaluate the efficacy of Nutri-medicinal plants in managing the HIV/AIDS Opportunistic infections, to be conducted according to good laboratory practices (GLPs)
 Uganda 2021-01-06 2024-01-06 Medical and Health Sciences Degree Award
Laban Musinguzi Kashaija
ID: UNCST-2020-R014407
 Rapid Assessment of Key Sexual and Reproductive Health Rights needs for LGBT+ persons & quality of available services to LGBT+ persons
REFNo: SS687ES

1. Conduct an assessment of the SRH Needs of LGBT+ Persons in Uganda

2. Conduct an assessment of the quality of SRHR available services to LGBT+ persons in Uganda

3. Generate information on barriers to access and the SRHR needs of LGBT+ persons

 Uganda 2021-01-06 2024-01-06 Social Science and Humanities Non-degree Award
Nelson Sewankambo K
ID: UNCST-2020-R014578
 Assessment of Health Professional Education Capacity in Uganda during the COVID-19 pandemic (ASHPECC)
REFNo: SS644ES

General Objective
To assess the readiness for and identify barriers and possible solutions to the implementation of the national guidelines for continuity of health professionals training in a safe manner during the COVID-19 pandemic

Specific Objectives
❖ To assess the readiness of HPTIs in Uganda to implement national guidelines for ODeL and in-person training.
❖ To identify the barriers to implementing national guidelines for ODeL and in-person trainings for learners and teachers among health professional training institutions in Uganda
❖ To identify possible solutions for existing barriers to the implementation of national guidelines for ODeL and in-person training at HPTIs in Uganda
❖ To identify the equity implications of different proposed models of learning?
 Uganda 2021-01-05 2024-01-05 Social Science and Humanities Non-degree Award
Achilles Katamba
ID: UNCST-2019-R000540
 Using human-centered design to develop a novel TB medication adherence technology
REFNo: HS1138ES

1. To design and prototype novel TB medication adherence technologies using research insights gained from previous human-centered design research.
2. To Obtain feedback on novel TB medication adherence technologies from TB patients, caregivers, family members, and health workers using an iterative prototyping approach.

 Uganda 2021-01-04 2024-01-04 Medical and Health Sciences Non-degree Award
Sarah Richardson Elizabeth
ID:
A MULTIMETHOD EXAMINATION OF THE STATUS OF EMERGENCY CARE IN UGANDAN HEALTH FACILITIES
REFNo: HS559ES

Broad objective: To maximise the in-depth understanding of the current status of emergency care delivery in Uganda, in order to inform the effective, efficient and sustainable implementation of the components of the WHO ECS toolkit and other emergency care interventions throughout the country. Specific objectives/aims: 1. To describe and establish the current knowledge, attitudes and beliefs of stakeholders towards emergency care. 2. To evaluate barriers and facilitators to the provision of emergency care in Ugandan facilities 3. To evaluate factors that will influence the implementation of emergency care education and implementation packages such as the WHO toolkit 4. To evaluate the current quality and process of the provision of emergency care and the associated total and preventable patient morbidity and mortality in emergency facilities
 UK 2020-12-24 2023-12-24 Medical and Health Sciences Degree Award
Nazarius Tumwesigye Mbona
ID: UNCST-2019-R000664
 Satisfaction and Knowledge on Emergency Medical services among Health providers and users in facilities implementing a Health System Strengthening project in Masaka and Bukomansimbi districts
REFNo: HS1136ES

 To assess the level satisfaction among health providers who were trained in EMS course under strengthening community health care system project in Masaka region
 To assess the level knowledge among health providers who were trained in EMS course under strengthening community health care system project in Masaka region
 To evaluate the change in the client satisfaction with EMS in facilities that are implementing strengthening community health care system project in Masaka region

 Uganda 2020-12-24 2023-12-24 Medical and Health Sciences Non-degree Award
Esther Bayiga Diana Zziwa
ID:
PEDESTRIAN SAFETY AND THE BUILT ENVIRONMENT IN KAMPALA CITY, UGANDA
REFNo: HS960ES

1. To examine the pattern in the spatial and temporal distribution of pedestrian safety in Kampala city, Uganda
2. To examine the influence of the built environment on the distribution pattern of pedestrian safety in Kampala city, Uganda
3. To explore perceptions of different categories of road users in Kampala city, Uganda on the significance of the different built environment variables to pedestrian safety.

 Uganda 2020-12-24 2023-12-24 Medical and Health Sciences Degree Award
Mark Kaddumukasa
ID: UNCST-2020-R001798
 Prevalence, semiology and risk factors of seizures among elderly patients attending Kiruddu Medical Outpatients in Uganda.
REFNo: HS970ES

Specific objectives
1. To determine the prevalence of seizures among elderly patients attending neurology clinic at Kiruddu hospital.
2. To describe the seizure semiology among elderly patients with seizures.

Secondary objectives
1. To determine the associated risk factors for seizures among elderly patients with cognitive deficts.
2. To determine the cognitive levels of elderly patients attending the neurology clinic at Kiruddu.
3. To explore the stigma associated with dementia among caregivers/families of AD patients.

 Uganda 2020-12-24 2023-12-24 Medical and Health Sciences Non-degree Award
Richard Kibombo
ID:
Use of the RMNCAH Scorecard at District and Health Facility Levels
REFNo: HS986ES

i)Assess the extent to which the RMNCAH scorecard has been adopted and utilised in selected districts and health facilities of Uganda;
ii)Examine the strategies and processes or procedures used to implement the RMNCAH scorecard in the selected districts and health facilities;
iii)Investigate the factors that enable and deter use of the RMNCAH scorecard in these districts and health facilities and the lessons learned;
iv)Determine the perceived positive and negative effects of implementing the RMNCAH scorecard in the selected districts and health facilities;
v)Propose practical recommendations for improving the use and institutionalising of the RMNCAH scorecard at the district and health facilities.
 Uganda 2020-12-24 2023-12-24 Medical and Health Sciences Non-degree Award
Moses Chemurot
ID:
Exploring stingless bee products for nutritional and medicinal values in Uganda (Bee-Nutri-Medicine project)
REFNo: HS1131ES

Investigate the potency of stingless bee honey and propolis as medicines for wounds and skin infections,Explore antimicrobial properties of honey and propolis collected from stingless bee colonies in Uganda,Determine the nutritional profiles of pollen and honey harvested from two stingless bee species in Uganda. This will guide in the promotion of bee pollen consumption as alternative sources of protein especially for poor rural households.,Explore stingless bee products for nutritional and medicinal purpose in Uganda,
 Uganda 2020-12-24 2023-12-24 Medical and Health Sciences Non-degree Award
Margaret Kabahenda
ID:
Strengthening the capacity of teachers to integrate nutrition education in school curricula to improve children’s dietary practices and physical actlivity so as to combat malnutrition [TEACH-Nutrition Project]
REFNo: A93ES

Determine the effectiveness of the proposed intervention model in improving: (a) teachers nutrition knowledge and ability to monitor pupils’ nutritional status; (b) pupils’ dietary practices and physical activity patterns; (c) parents’ knowledge of their children’s nutritional needs and their capacity to provide nutritious foods to their children; and (d) schools management’s commitment to address food and nutrition issues,Determine the barriers and supports for integrating nutrition education in school curricula,Develop an effective nutrition education intervention model that can easily be integrated in lower primary school curricula,Characterize the available nutrition education training programs, materials, and the types and innovation habits of actors engaged in school nutrition education,
 Uganda 2020-12-21 2023-12-21 Agricultural Sciences Non-degree Award
Chrispo Maali
ID:
Remuneration and Performance of Teachers in Government Aided Secondary Schools in Kasese District, Western Uganda
REFNo: SS512ES

1.To explore the forms of remuneration in government aided secondary schools in Kasese District.
2.To examine the level of teachers performance in government aided secondary schools in Kasese District
3.To examine the relationship between remuneration and teacher performance in government aided secondary schools in Kasese District.

 Uganda 2020-12-21 2023-12-21 Social Science and Humanities Degree Award
Clement Okello Dove
ID: UNCST-2020-R014649
 TREATMENT RESPONSE AND TREATMENT RELATED MORTALITY IN PATIENTS WITH ACUTE MYELOID LEUKAEMIA AT THE UGANDA CANCER INSTITUTE
REFNo: HS946ES

1. To describe the clinical characteristics of patients with acute myeloid leukaemia at the Uganda Cancer Institute. 2. To determine the induction treatment response rate in patients with acute myeloid leukaemia at the Uganda Cancer Institute. 3. To determine the rate of induction treatment related mortality in patients with acute myeloid leukaemia at the Uganda Cancer Institute. 4. To determine the predictors of induction related mortality in patients with acute myeloid leukaemia at the Uganda Cancer Institute.
Uganda 2020-12-21 2023-12-21 Medical and Health Sciences Non-degree Award
Lydia Nakiyingi
ID:
Development of large-scale panel of TB patient urine and serum samples to serve as standards for detection of TB LAM in HIV-positive and negative presumptive TB patients
REFNo: HS1006ES

Primary:
•Estimate the sensitivity of the investigational urine LAM test for detection of culture-confirmed Mycobacterium tuberculosis infection among individuals with clinical signs and/or symptoms of TB.
•Examine the effect of HIV infection and CD4 cell level on sensitivity of these assays
•Compare the sensitivity of the existing FujiLAM and AlereLAM assays with new investigational LAM tests

Secondary:
•Use large-scale samples to compare the immunological properties of urinary LAM in different patients, and to perform structural analyses of the urinary LAM antigens
• Develop and distribute aliquots of characterized large-scale urine samples for standardization and optimization of a point-of-care format of the investigational urine LAM assay.


Uganda 2020-12-18 2023-12-18 Medical and Health Sciences Non-degree Award
Janet Nakigudde
ID: UNCST-2019-R000444
 Effectiveness and Implementation of an Early Childhood School-Based Mental Health Intervention in Low-Resourced Communities in Hoima and Kampala districts-Uganda
REFNo: HS1057ES

1. To evaluate the short and long term effectiveness of Professional Development (PD alone) and Professional Development plus wellness Training (PDT)
2. To examine the effectiveness mechanisms and theory of change underlying the EBIs
3. To examine implementation contextual factors and mechanisms that contribute to teachers' uptake and sustainment of EBI strategies within PD and PDT schools.
Uganda 2020-12-18 2023-12-18 Medical and Health Sciences Non-degree Award
View Sort By:

"A prosperous Science and Technology Led Ugandan Society."

NRIMS