Bjorn Van Campenhout -
ID: UNCST-2020-R014080
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Demand and supply factors constraining the emergence and sustainability of an efficient seed system in Uganda.
REFNo: SS603ES
The proposed study aims to provide innovative, evidence-based insights on the:
i. Mechanisms that encourage more efficient marketing and distribution of seed and traits at various levels of commercialization and across heterogeneous populations and agro-ecologies (“improving seed supplyâ€), and;
ii. Mechanisms that nudge farmers—youth, women, and smallholders—into using improved varieties and quality seed, including varieties and seed for climate-smart and nutrient-dense crops and traits (“enhancing seed demandâ€).
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Belgium |
2020-09-23 |
2023-09-23 |
Social Science and Humanities |
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Non-degree Award |
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Charles Drago Kato Drago
ID: UNCST-2021-R012897
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Clinical evaluation of novel plasma biomarkers for stage diagnosis among sleeping sickness patients in Uganda
REFNo: HS520ES
1. To identify plasma biomarkers associated with either early or late stage T. b. gambiense disease using proteomics methods and compare with those previously identified for T. b. rhodesiense.
2. To determine the potential of plasma biomarkers identified using proteomics methods in discriminating between early and late stage patients for both T. b. rhodesiense and T. b. gambiense sleeping sickness.
3. To initiate the setup of a biomarker research team and laboratory at Makerere University.
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Uganda |
2020-09-18 |
2023-09-18 |
Medical and Health Sciences |
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Non-degree Award |
.JPG)
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Sarah Nanzigu
ID:
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Effects of Co-administration of HAART and Antiepileptic drugs on pharmacokinetics, seizure control and ART outcomes among Ugandans aged 0-24 years.
Short title: Study of Co-medication with HAART and antiEpileptic Drugs
Acronym: Co-HED
REFNo: HS546ES
General Study Objective: To evaluate the pharmacokinetics and clinical effects of HIV and antiepileptic co-medication among Ugandan patients aged 0-24 years.
SUB-STUDY I
This will be a cross-sectional, evaluating short and long-term effects of HAART-AED co-medication on the pharmacokinetics and treatment outcomes of HAART among Ugandans aged 0-24 years.
Specific objectives for sub-study 1
The specific objectives to be addressed during this sub-study will include the following:
1. To determine the effect of combined treatment with HAART and antiepileptic agents on virological control among HIV infected Ugandans aged 0-24 years, attending Baylor HIV clinic.
2. To determine the effect of combined treatment with HAART and antiepileptic agents on the immunological outcomes of HIV infected Ugandans aged 0-24 years, attending Baylor HIV clinic.
3. To determine the effect of combined treatment with HAART and antiepileptic agents on the safety of Ugandans aged 0-24 years, attending Baylor HIV clinic.
The study shall as well address secondary objectives that include the following:
1. To determine the effect of combined treatment with HAART and antiepileptic agents on efavirenz plasma concentrations, among HIV infected Ugandans aged 0-24 years attending Baylor HIV clinic.
2. To determine the effect of combined treatment with HAART and antiepileptic agents on lopinavir plasma concentrations, among Ugandans aged 0-24 years attending Baylor HIV clinic.
SUB-STUDY II
The main objective of this sub-study will be to evaluate the effect of HAART on the pharmacokinetics and clinical outcomes of carbamazepine and sodium valproate among Ugandans aged 0-24 years during 6 months of combined treatments for HIV and epileptic conditions.
Specific Objectives for sub-study II
1. To determine the effect of HAART on the pharmacokinetics of carbamazepine among Ugandans aged 0-24 years, during 6 months of combined treatment for HIV and epilepsy
2. To determine the effect of HAART on the pharmacokinetics of sodium valproate among Ugandans aged 0-24 years, during 6 months of combined treatment for HIV and epilepsy
3. To determine the effect of HAART on seizure control among Ugandans aged 0-24 years, during 6 months of combined treatment for HIV and epilepsy
4. To determine the effect of HAART on the safety of antiepileptic agents among Ugandans aged 0-24 years, during 6 months of co-medication with HAART and either carbamazepine or sodium valproate
Secondarily, we shall determine concentrations of the respective antiretroviral agents (efavirenz or lopinavir). The concentrations of the antiretroviral drugs estimated from study 11, will be compared to those obtained in study 1 in an attempt to establish a direct link of the effect of AEDs on the pharmacokinetics of antiretroviral agents. In addition, we shall attempt to evaluate the likelihood of a concentration-dependent effect of efavirenz on the pharmacokinetics and treatment outcomes of antiretroviral agents.
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Uganda |
2020-09-18 |
2023-09-18 |
Medical and Health Sciences |
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Non-degree Award |
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Lucas Ampaire
ID:
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Microbial contamination of locally prepared beverages vended in Kisenyi parish, Kampala: Prevalence, associated factors and utility of rapid diagnostic tests
REFNo: HS586ES
1. To determine the prevalence and factors associated with microbial contamination of locally prepared beverages vended in Kisenyi Parish, Kampala, Uganda.
2. To determine the common contaminating microbial agents in the locally prepared beverages and their antibiotic sensitivity patterns.
3. To assess the performance of MaxSignal® E. coli O157 Strip Test Kit and MaxSignal® Salmonella Strip Test Kit on food-borne pathogens in locally prepared beverages vended in Kisenyi Parish, Kampala , Uganda
4. To develop and evaluate the performance of a local multiplexed strip/cassette for rapid detection of common food contaminants
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Uganda |
2020-09-18 |
2023-09-18 |
Medical and Health Sciences |
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Degree Award |
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Jane Achan Edwin
ID: UNCST-2023-R005498
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Malaria among patients admitted with COVID-19: a case series
REFNo: HS666ES
General Objective: To understand the burden and clinical consequences of malaria among COVID-19 patients
Specific objectives
1. To determine the prevalence of malaria among patients with COVID-19 and to evaluate the risk of malaria following hospital discharge.
2. To determine the magnitude of previous exposure to malaria among patients with COVID-19
3. To document the impact of malaria on clinical outcomes of patients with COVID-19
4. To assess the potential impact of currently used antimalarial drugs (artemether-lumefantrine and dihydroartemisinin-piperaquine) on clinical outcomes among COVID-19 patients prescribed these drugs as per current clinical indications
5. To document the clinical spectrum of malaria among patients with COVID-19
6. To evaluate the potential interactions between COVID-19 and other infectious diseases including HIV/AIDS and TB
7. To describe health worker perspectives on the management of malaria in COVID-19 patients
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Uganda |
2020-09-16 |
2023-09-16 |
Medical and Health Sciences |
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Non-degree Award |
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Nathan Fiala
ID: UNCST-2022-R009060
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The Long-term Impacts of a cash-based Employment Program in Northern Uganda
REFNo: SS501ES
1.To evaluate the long-term effectiveness of a cash-based youth employment program using a randomized controlled trial.
2. To understand the effect of COVID-19 and restrictions on youth employment
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USA |
2020-09-16 |
2023-09-16 |
Social Science and Humanities |
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Non-degree Award |
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JANE AMUGE
ID:
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Upholding Cooperative Identity as a crucial determinant of Cooperative Resilience: A case study of cooperatives in Uganda
REFNo: SS544ES
1. To identify how cooperatives have optimised their unique character enshrined in their definition, principles and values to cope, remain stable, adapt to situations, innovate and remain resilient in the face of adversity.
2. To establish how adherence or non-adherence to the definition, principles and values of cooperatives have increased their risks, vulnerabilities and contributed to their instability, limited adaptation and innovation thus their lack of resilience.
3. To find out the influence of other factors apart from cooperative identity, on cooperative resilience or the lack of it.
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Uganda |
2020-09-16 |
2023-09-16 |
Social Science and Humanities |
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Non-degree Award |
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Gladys Nakalema
ID:
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DECISIONAL CAPACITY AND COERCION AMONG PATIENTS ENROLLED IN RESEARCH AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: SS479ES
i. To assess the decisional capacity of research participants at Mbarara Regional Referral Hospital (MRRH)
ii. To assess the level of coercion to consent to study participation among research participants at MRRH
iii. To determine the association between decisional capacity and level of coercion to consent to study participation among research participants at MRRH
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Uganda |
2020-09-15 |
2023-09-15 |
Social Science and Humanities |
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Degree Award |
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Annet Nakaganda
ID:
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Developing a Standardized tool for cancer risk factors Surveillance: A case study of the prevalence of cancer risk factors in Eastern Uganda (CARIFAS)
REFNo: HS754ES
1. Developing a standardized tool for assessing cancer risk factors in Uganda.
2. Estimating the prevalence of cancer risk factors in Mayuge district (Eastern Uganda
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Uganda |
2020-09-15 |
2023-09-15 |
Medical and Health Sciences |
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Non-degree Award |
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Dennis Muhanguzi
ID: UNCST-2019-R001101
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EVALUATION OF THE SAFETY AND EFFICACY OF VECTOCLORÃ’-PLUS EMULSIFIABLE CONCENTRATE [E.C.]: A RANDOMISED SINGLE-BLINDED POSITIVE CONTROLLED MULTI-SITE ACARICIDE FIELD TRIAL
REFNo: NS129ES
General objectives
To determine the efficacy and safety of Vectoclor®-Plus E.C. (Ceva Santé Animale, Libourne) hereinafter called Vectoclor®-Plus when used on cattle for tick control.
Specific objectives
-To determine the efficacy of Vectoclor®-Plus when used on cattle for tick control
-To determine the safety of Vectoclor®-Plus when used on cattle for tick control
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Uganda |
2020-09-15 |
2023-09-15 |
Natural Sciences |
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Non-degree Award |
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George Lugalambi William
ID:
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UNICEF Handwashing with Soap
REFNo: SS551ES
What factors constrain and prevent individuals and households from washing their hands with soap?
What knowledge, attitudes and practices are prevalent regarding handwashing with soap?
What needs to be done to scale up handwashing with soap initiatives?
Establish barriers to change and how the strategy can efficiently and effectively address them.
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Uganda |
2020-09-15 |
2023-09-15 |
Social Science and Humanities |
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Non-degree Award |
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Numa Memisevic
ID:
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Breaking stereotypes and remodeling the concept of sexual violence prevention by building resiliency and defense skills among vulnerable women
REFNo: SS542ES
The aim of the foregoing proposal is to test a novel empowerment-based sexual assault prevention
training initiative targeting women at high risk for sexual violence in Uganda. This intervention
focuses on both non-physical and physical measures.
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Yugoslavia |
2020-09-10 |
2023-09-10 |
Social Science and Humanities |
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Degree Award |
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Hesbon Owilla Hansen
ID:
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QUANTITATIVE AND QUALITATIVE STUDY ON INNOVATION FOR MEDIA VIABILITY IN EAST AFRICA
REFNo: SS417ES
1. To bolster the viability of media outlets
2. To galvanize media innovation in East Africa, with a focus not just on creative content but on new and sustainable business models for the future.
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Kenya |
2020-09-08 |
2023-09-08 |
Social Science and Humanities |
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Non-degree Award |
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Fatuma Namusoke University
ID:
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Barriers, knowledge and antimalarial antibodies in relation to Intermittent Preventive Treatment in pregnancy use in Kawempe National Referral Hospital
REFNo: HS620ES
1. Explore the barriers of IPTp implementation in Kawempe National Referral Hospital
2. To describe the knowledge and perceptions of IPTp among mothers Kawempe National Referral Hospital
3. To determine the association between quantity and quality of antimalarial antibodies in puerperium and use of IPTp during pregnancy
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Uganda |
2020-09-04 |
2023-09-04 |
Medical and Health Sciences |
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Non-degree Award |
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Mark Jordans
ID: UNCST-2020-R014861
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Increasing the efficiency of an education programme to facilitate
rapid adoption and sustainable scale-up.
REFNo: SS451ES
Aim: To increase the efficiency and scalability of the Can’t Wait to Learn (CWTL) programme, through increasing access, attendance, retention and facilitating programme adoption.
The specific objectives of the present research studies are:
1) To develop and test a caregiver engagement intervention to increase children’s equitable access to, attendance of and retention in CWTL;
2) To assess and optimise the CWTL implementation team model to facilitate rapid adoption and scale up of the programme;
3) To evaluate the value for money of CWTL and identify drivers and drainers of value for money.
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Netherlands |
2020-09-04 |
2023-09-04 |
Social Science and Humanities |
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Non-degree Award |
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Pauline Byakika-Kibwika
ID: UNCST-2019-R001206
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Optimizing malaria treatment for HIV-malaria co-infected individuals by addressing drug interactions between Artemether-Lumefantrine and Efavirenz.; a randomized trial
REFNo: HS820ES
General Objective: To utilize innovative interventions to overcome drug interactions between artemether-lumefantrine and efavirenz to guide malaria treatment for individuals co-infected with HIV and malaria.
Specific objectives:
1. To determine the safety and Pharmacokinetics of the double dose artemether-lumefantrine when administered with efavirenz based ART among healthy volunteers (malaria negative and HIV negative individuals).
2. To determine the safety and Pharmacokinetics of the 5-day course of artemether-lumefantrine when administered with efavirenz based ART among healthy volunteers (malaria negative and HIV negative individuals).
3. To determine the safety, pharmacokinetics and malaria treatment outcome of a standard dose of artemether-lumefantrine compared to double of the standard dose for weight and a 5-day course of artemether-lumefantrine for treatment of uncomplicated malaria among HIV-Malaria co-infected individuals receiving efavirenz-based ART.
4. To determine the safety and Pharmacokinetics of artemether-lumefantrine when administered with Dolutegravir based ART among HIV-malaria co-infected individuals
|
Uganda |
2020-09-04 |
2023-09-04 |
Medical and Health Sciences |
|
Non-degree Award |
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Grace Kagoro
ID: UNCST-2021-R013951
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Digital citizen science for community-based resilient environmental management
REFNo: NS126ES
1. Enhance a network of hazard reporters and participating communities across the targeted districts.
2. Strengthen the academic capacities (PhD & MSc) of the two partner institutions hence development of
evidence based research on disaster risk reduction and sustainable rural livelihood strategies.
3. Generate knowledge factors controlling the spatial- temporal distribution of environmental risks and land
degradation.
4. Contribute to the establishment of a platform for multi-actor dialogue of environmental resilience.
5. Contribute towards the interpretation and policy recommendations to the policy makers basing on the
collected data about environmental natural hazards, resilience and mitigation measures.
6. Increase community awareness about effect of human activities on accelerating environmental natural
hazards, their resilience and mitigation measures.
7. Develop and test new methods to initiate multi-lateral interactions between rural communities, district
authorities and scientists and favor the implementation of resilient livelihood practices.
8. Enhance the knowledge and skills of the Geo-observers as environmental facilitators to be able to serve as
interface between the communities and the scientists.
|
Uganda |
2020-09-04 |
2023-09-04 |
Natural Sciences |
|
Degree Award |
|
Laban Musinguzi Kashaija
ID: UNCST-2020-R014407
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Baseline Survey on HIV Prevention Programme among Key Populations in Uganda
REFNo: SS508ES
The baseline study shall establish knowledge on:
• KPs ability to protect themselves against HIV
• The level of access to KP friendly health services
• The level of structural barriers to HIV treatment and prevention for KPs
• The level of organizational capacity of programme partners & cross-country programme interventions.
|
Uganda |
2020-09-04 |
2023-09-04 |
Social Science and Humanities |
|
Non-degree Award |
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Edgar Tusingwire Bagarukayo Bagarukayo
ID:
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Analysis of Capacity development and Participation of Local companies in the Oil and gas industry: A case of Ugandan Companies
REFNo: SS515ES
-To examine the approaches and mechanisms used by Ugandan Companies’ for capacity development;
- To examine the roles of various capacity building actors and how they facilitate or inhibit capacity development;
- To analyze how Ugandan Companies’ have deployed the capacity acquired to participate in the oil and gas industry in Uganda.
|
Uganda |
2020-09-04 |
2023-09-04 |
Social Science and Humanities |
|
Degree Award |
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PAUL ISABIRYE
ID:
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Determinants of Family Planning Services uptake among first time parents in Uganda
REFNo: HS868ES
1. To determine the level of uptake of family planning services among first time parents.
2. To identify the individual factors that determine family planning services uptake among the first time parents.
3. To assess the contextual drivers of family planning services uptake among the first time parents.
4. To assess family planning services uptake challenges among first time parents.
|
Uganda |
2020-09-02 |
2023-09-02 |
Medical and Health Sciences |
|
Non-degree Award |
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