Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Ahna Ballonoff Suleiman
ID: UNCST-2025-R019613
Thrive Together: Strengthening Contraception through Lived Experience of Flourishing
REFNo: SS4403ES

1. Bring existing, validated VFP and human flourishing frameworks and evidence into rigorous dialogue; 2. ground understanding of common VFP and human flourishing domains in lived experience expertise of culturally diverse young people, women and couples; 3. Engender first-ever expert consensus on the common domains of human flourishing and VFP; 4. Deliver evidence-based, consolidated guidance to programmers and decision-makers to advance VFP as part of human flourishing, and human flourishing as part of VFP.
USA 2025-10-08 19:23:37 2028-10-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Moffat  Nyirenda Joha
ID: UNCST-2020-R019333
Understanding the Effects of Behavioural Risk Factors and Lifestyle Changes Among Non-overweight and Obese Type 2 Diabetes Mellitus Patients in Malawi and Uganda.
REFNo: HS6497ES

Main Objective:
• To determine whether behavioural risk factors (diet and physical activity) contribute to NOW T2DM and to assess whether current national lifestyle change guidelines have similar effects on glucose control and other outcomes among NOW and obese T2DM patients in Malawi and Uganda.

Specific Objectives:

i. To establish a cohort of newly diagnosed NOW and obese T2DM patients and matched non-diabetic controls in Malawi and Uganda.
ii. To compare baseline dietary and physical activity patterns among NOW and obese T2DM participants and their matched controls.
iii. To administer health education based on national guidelines and compare 6-month outcomes (weight loss and glucose control) in NOW versus obese participants.

Malawi 2025-10-08 19:03:35 2028-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ANN AKITENG ROSE
ID: UNCST-2025-R019916
Assessing Healthcare Barriers and Identifying Implementation Strategies to Mitigate Cardiovascular Risks Among Market Vendors in Urban Markets in Kampala and Mbarara, Uganda
REFNo: HS6472ES

The aim of this study is to generate formative quantitative data on the health status, cardiovascular disease (CVD) risk factors, daily routines, and healthcare access and barriers of market vendors in Uganda in order to identify opportunities for culturally appropriate and feasible lifestyle modification interventions and potential implementation strategies to reduce CVD risk.
Uganda 2025-10-08 18:59:30 2028-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
PATIENCE AYESIGA
ID: UNCST-2023-R003499
The implications of wetland dynamics on water qiuality for conservation of Rwizi macro catchment south western Uganda
REFNo: SS4498ES

To characterize the spatial-temporal dynamics and explore drivers of wetland degradation for middle Rwizi catchment. 2.To assess the implications of wetland degradation on sediment for middle Rwizi catchment. 3.To analyze the influence of nutrients on water quality for middle Rwizi catchment. 4.To evaluate the effectiveness of existing conservation develop suitable restoration and conservation mechanisms for improved catchment health of middle Rwizi system.
Uganda 2025-10-08 18:58:01 2028-10-08 Social Science and Humanities Degree Award
Obondo Sande James
ID: UNCST-2019-R000241
Effect of Mycobacterium tuberculosis and its cell wall glycolipids on the HIV Reservoir in CD4+ T cells
REFNo: HS5439ES

1. To determine if MTB molecules (e.g. PIM6, LAM, MTB lysate) induce HIV expression in memory CD4+ T cells from ART-suppressed HIV infected persons.

2. To determine the size of peripheral HIV reservoir in memory CD4+ T cells in HIV infected individuals with active TB compared to HIV infected individuals with history of documented treated TB, LTBI, and no LTBI (HIV-monoinfected).

3. To assess longitudinal changes in the size of peripheral HIV reservoir in memory CD4+ T cells in HIV infected individuals with active TB before initiation of TB treatment and at the end of treatment

Uganda 2025-10-08 18:16:22 2028-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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