Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
John Bosco Ddamulira Mayanja
ID: UNCST-2022-R010819
Burden of Snakebites and Snakebite Envenoming in Uganda: A community survey and Health facility Audit
REFNo: HS566ES

I. Determine the incidence of snakebite envenoming in Uganda
II. Characterize the snakebites and snakebite envenoming in Uganda
III. Describe the snakebite envenoming outcomes
IV. To describe snakes commonly responsible for snake bites in Uganda.
V. Establish the spatial distribution of the common snake species in Uganda
VI. Identify the community practices following snakebite envenoming in Uganda
VII. Assess health facility capacity (human, equipment & supplies) to manage snakebite envenoming

Uganda 2020-06-30 2023-06-30 Medical and Health Sciences Non-degree Award
VICTORIA WALUSANSA ABALIWANO
ID: UNCST-2021-R012155
Exploring the Molecular Spectrum of Colorectal Cancer in Uganda
REFNo: HS667ES

Primary Objective: Estimate the prevalence of BRAF and KRAS mutations, CIMP, and MSI in colorectal tumors in the KCR.
Secondary Objectives:
(1) Describe the demographic and clinical characteristics of colorectal cancer cases in the KCR.
(2) Evaluate associations of demographic and clinical characteristics with the prevalence of BRAF and KRAS mutation, CIMP, and MSI in colorectal cancer cases in the KCR.
(3) Evaluate associations of survival time with tumor molecular phenotypes (BRAF, KRAS, CIMP, MSI) and other participant information.

Uganda 2020-06-30 2023-06-30 Medical and Health Sciences Non-degree Award
Sachin Gathani Gathani
ID:
Effect of Covid-19 lockdown measures on coffee farmers in Central and Western Uganda
REFNo: SS486ES

This study aims to understand the effect of COVID-19 and the consequent lockdown
measures on coffee farming households in the JDE Farm College a program being
implemented by TechnoServe (a non-profit organization). JDE is working in partnership with Technoserve to train coffee farmers on coffee agronomy best practices, helping them improve
the quality and yields of their coffee trees, which in turn will increase their income in the long term. Farmers are enrolled in the training program every 2 years in what is referred to as a
“cohort”. Enrolled farmers come together and form a focal farmer group and a farmer trainer is appointed to run the training sessions. Coffee demo plots are implemented in order to train farmers in real-life conditions. The trainings are conducted every month and attendance is tracked. Laterite is a research, data and advisory firm with offices in Kampala who is partnered with TechnoServe to provide research support for the monitoring and evaluation activities of the TechnoServe Farm College Program.
The main objective of the study is to generate timely data and insights for TechnoServe and coffee industry stakeholders on how coffee farming households that are part of their agronomy training program are affected by COVID-19 crisis and the consequent lockdown measures to address Covid-19. This will be useful for TechnoServe, to inform their programming including targeting interventions to areas that need them most and considering options for redirecting
resources from coffee agronomy to other types of training.
The results from this study will result in monthly briefs (not an academic study) that
demonstrate farmer’ knowledge of COVID-19 and how the lockdown measure may have
affected their farming activities including access to input, farms and markets.
Kenya 2020-06-30 2023-06-30 Social Science and Humanities Non-degree Award
Arthur Kwizera
ID: UNCST-2021-R012928
A multicenter, prospective, randomized, placebo-controlled, open label, stepped wedge clinical trial of respiratory support with continuous positive airway pressure or high-flow oxygen therapy in adults with acute hypoxemic respiratory distress in Uganda.
REFNo: HS523ES

Primary objective
To assess the efficacy of CPAP and HFNC in improving 28-day survival in patients with AHRF.

Secondary objectives
Secondary objectives are to:
- Determine the feasibility, safety, tolerance and comfort of CPAP and HFNC;
- Evaluate the impact of CPAP and HFNC on morbidity, including the need for intubation, ventilator free days, organ dysfunction, and hospital length of stay.


Uganda 2020-06-29 2023-06-29 Medical and Health Sciences Degree Award
Musa Sekikubo
ID: UNCST-2020-R014404
Maternal, Neonatal and Infant Outcomes at Kawempe National Referral Hospital
REFNo: HS623ES

COMPONENT1: Will describe baseline maternal and neonatal outcomes using anonymised data collected using the routine Kawempe electronic medical records (EMR) system. For this, we seek approval to perform a secondary analysis of anonymised data from Kawempe National Referral Hospital and request for a waiver of individual informed consent since the data will be de-identified.
COMPONENT 2: Will collect comprehensive data on pregnancy, neonatal and infant outcomes in a prospective cohort of approximately 4,000 pregnant women enrolled in the first and second trimesters while attending antenatal care at Kawempe Hospital with follow-up of the mother-infant pairs up until around 9 months of age. Written informed consent will be obtained from all mothers, and from the fathers of the babies if they are available.

Uganda 2020-06-27 2023-06-27 Medical and Health Sciences Non-degree Award
Betty Akurut Enyipu
ID:
A phenomenological Study of the Role of Christian Values and Culture in Conflict Resolution among couples of St. Andrew and Phillip’s Cathedral in Mukono, Uganda.
REFNo: SS460ES

1.To examine Christian values that promote conflict resolution among couples of St. Phillip’s and Andrew’s Cathedral of Mukono. 2. To assess Christian values that hinder conflict resolution among couples of St. Phillip’s and Andrew’s Cathedral of Mukono. 3. To examine cultural factors that promote conflict among couples of St. Phillip’s and Andrew’s Cathedral in Mukono. 4. To assess the cultural factors that perpetuate conflict among couples of St. Phillip’s and Andrew’s Cathedral of Mukono. 5. To examine strategies for resolving conflict among couples of St. Phillip’s and Andrew’s Cathedral of Mukono. 6. To examine strategies for preventing future occurrence of conflict among couples of St.Phillip’s and Andrew’s Cathedral of Mukono.
Uganda 2020-06-27 2023-06-27 Social Science and Humanities Degree Award
Richard Kajura Kajjura
ID:
Determinants of childhood stunting reduction: A case of Uganda
REFNo: HS698ES

Overall objective
To understand trends and determinants of stunting prevalence reduction in Uganda in the period between1995 and 2016
Specific objective
•To understand trends that may be linked to stunting prevalence in the period between 1995 and 2016.
•To determine the determinants of stunting reduction among children born in the period 1995 and 2016.
•To determine the drivers and facilitators of stunting among mothers with children born between the years of 1995-2016; or experts implementing policies.

Uganda 2020-06-26 2023-06-26 Medical and Health Sciences Non-degree Award
Claudia Ringler
ID:
Reaching Smallholder Women with Information Services and Resilience Strategies to Respond to Climate Change
REFNo: SS464ES

The project goal is to reduce poverty, improve food security, and reduce natural resource degradation for more than 30,000 women in smallholder farm households through piloting climate-smart agricultural approaches using innovative information services in parts of India, Kenya and Uganda. The purpose of the project is that more than 30,000 women farmers and farm families will use information on climate-smart agricultural technologies, practices, and principles for increased resilience to the potentially adverse impacts of climate change, contributing to closing gendered yield gaps, enhanced equity and inclusion and, further, to the CGIAR system-level objectives.
Germany 2020-06-23 2023-06-23 Social Science and Humanities Non-degree Award
Nicolette Nabukeera Barungi
ID: UNCST-2022-R008960
Situation of Adolescent-Friendly Health Services and Strategies for Enhancing their Reach and Coverage Focusing on RMNCAH in Uganda
REFNo: HS582ES

1. To describe the coverage, models of delivery and utilization of adolescent friendly health services from the perspective of RMNCAH in Uganda.
2. To explore the factors that enable (strengths or facilitators) and hinder (weaknesses or barriers) the delivery of AFHS in health facilities from the perspective of RMNCAH in Uganda.
3. To identify barriers and facilitators of expansion of AFHS to reach more health facilities in Uganda.

Uganda 2020-06-22 2023-06-22 Medical and Health Sciences Non-degree Award
eve Nakabembe
ID:
The safety and immunogenicity of a combined pertussis containing vaccine for HIV-infected pregnant women and their newborns: a randomized clinical trial
REFNo: HS626ES

To determine the safety and immunogenicity of a combined pertussis containing vaccine-Tdap for HIV-infected pregnant women and their newborns
Uganda 2020-06-22 2023-06-22 Medical and Health Sciences Degree Award
Janet SEELEY
ID:
The impact of COVID-19 and related public health response on vulnerable populations in Uganda
REFNo: SS455ES

This study aims to understand how the current COVID-19 impact as well as information and response affects the daily lives of these vulnerable groups and inform responses to the emerging needs.
In this qualitative study we will assess:
- Participants’ knowledge of COVID-19, and related public health response
- The impact of COVID-19, and related public health response on participants and their children’s, and community members day to day life (health, education, economic, social, psychological)
- Participants’ concerns about COVID-19, and related public health response
- Actions participants have taken in response to the information about and public health response to reduce the spread of COVID-19
- Recommendations for measures to reduce spread and help support/respond to participants concerns

UK 2020-06-17 2023-06-17 Social Science and Humanities Non-degree Award
Tom  Kakaire
ID:
Coping strategies of individuals from low income country organizations in collaborations with individuals from high income country organizations
REFNo: SS429ES

1) To identify individuals’ behavioral responses that result from specific conditions of structural inequality at various stages of workplace collaborations in which they participate
2) To identify generalisable patterns in the behavioural coping strategies of Low income Country (LIC) researchers, which are triggered by their experiences of structural inequality at specific stages of their collaborations with High Income Country (HIC) researchers
3) To develop a model that predicts behavioural patterns arising from a sequential order of conditions in unequal research collaborations by adapting an existing model from the acculturation literature
Uganda 2020-06-16 2023-06-16 Social Science and Humanities Degree Award
Mpimbaza Arthur Kagoya
ID:
Evaluating malaria case management at public health facilities in the Busoga sub-region, Uganda
REFNo: HS618ES

1.To evaluate the availability and readiness of public health facilities in providing malaria case management services to patients in the Busoga sub-region.
2.To evaluate the quality of malaria case management practices received by patients seeking care at public health facilities in the Busoga sub-region.
3.To assess health worker competencies in malaria case management standards at public health facilities in the Busoga sub-region
To explore provider and user perspectives of the state of quality of services and opportunities for improving service delivery
Uganda 2020-06-16 2023-06-16 Medical and Health Sciences Non-degree Award
Semitala Fred
ID: UNCST-2020-R014202
TB Screening Improves Preventive Therapy Uptake (TB SCRIPT study)
REFNo: HS628ES

The overall objective of this application is to evaluate the impact of a potentially more effective and cost-effective TB screening strategy, which is the next step required for successful uptake of TBPT.

Uganda 2020-06-16 2023-06-16 Medical and Health Sciences Non-degree Award
Esther Buregyeya
ID: UNCST-2020-R014116
A Mobile Health Intervention with Transfer of Social Bundle Incentives to Increase Treatment Adherence in Tuberculosis Patients in Uganda
REFNo: HS656ES

1a: To identify perceptions, acceptability, perceived barriers and facilitators for the use of VDOT among TB patients, health providers and community DOT volunteer workers in Uganda.
1b: To adapt the VDOT platform to the local context using the information from the qualitative interviews and create the DOT Selfie intervention with automated social bundle incentives to reward adherence
2: To conduct a pilot randomized trial to compare treatment adherence between patients using DOT Selfie and in-person DOT

Uganda 2020-06-16 2023-06-16 Medical and Health Sciences Non-degree Award
Jennifer Palmer
ID:
The lives & livelihoods of displaced health workers in Uganda
REFNo: HS495ES

By studying the relationships between these global health trends, humanitarian HRH governance in Uganda, and the experiences of displaced HCWs, we aim to provide an in-depth case study of the political dynamics, contradictions and lived realities affecting HRH development in a contemporary refugee response. We do so to prompt debate in domestic and international policy circles which might lead to better inclusion of displaced HCWs in this and other humanitarian responses and, ultimately, explore avenues to improve the lives, livelihoods and future health systems of crises-affected populations.
Specific objectives of this work include:
Map HRH governance initiatives affecting displaced HCWs in Uganda alongside contemporary trends in the health and protection fields which influence HRH decision-making for displaced HCWs by policy actors.
Document the migration and livelihood trajectories of displaced HCWs in relation to their motivations and aspirations for health system building and self-reliance during their experiences of different phases of conflict and displacement.
Identify formal and informal bureaucratic practices which regulate HRH development for displaced HCWs as well as the networks, resources and solutions displaced HCWs draw on to secure access to health livelihoods.
Explore displaced HCW perceptions of the quality of public health responses for refugees in Uganda, including links between continuity of care for patients and continuity of practice for healthcare providers.
Through RECAP collaborators and other interested policy actors, contribute evidence and analyses that could improve employment of displaced HCWs to HRH governance initiatives and processes identified during the research process.

Canada 2020-06-12 2023-06-12 Medical and Health Sciences Non-degree Award
Anders Jensen
ID:
Digitizing Revenue Collection in Northern Uganda
REFNo: SS456ES

This project studies the introduction of a digital tax assessment and collection system into local tax administration in Northern Uganda. We will partner with the UNCDF and Ministry of Local Government to measure the impacts of the digitized system on the process of tax assessment and revenue collections relative to a status quo manual registration and collection system. To study how the digital system affects the accuracy of tax assessment, the research team will conduct independent, objective assessments of
taxpayers and match them to official records. This exercise will provide an opportunity to shed light on how gaps in assessment accuracy correlate with tax compliance to investigate how accuracy and perceived fairness in the
assessment step of taxation impact payment and revenues.
Denmark 2020-06-11 2023-06-11 Social Science and Humanities Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
Assessment of the feasibility of collection of COVID 19 Immune/convalescent Plasma in Uganda
REFNo: HS684ES

General objective
The overall objective of this project is to assess the feasibility collecting and storing of COVID-19 convalescent plasma (CCP) in Uganda.

Specific objectives
1. To determine the proportion of Ugandan COVID-19 survivors who consent for CP donation
2. To determine the levels of SARS-CoV-2 virus antibodies among Ugandan COVID 19 recoveries
3. To establish a biobank of well annotated and well characterized plasma aliquots from COVID 19 recovered patients for future biomedical studies
Uganda 2020-06-11 2023-06-11 Medical and Health Sciences Non-degree Award
Martin  Muhereza
ID:
Policy and Structural reforms of Electricity in Uganda in the context of social economic welfare
REFNo: SS424ES

1.To examine the alignment of electricity reforms in Uganda with theoretical benefits of power sector reforms
2. To analyze the relationship of electricity reforms with the levels of electricity accessibility,reliability,and affordability in informal settlements.
3.To generate knowledge beneficial to policy makers and planners interested in the contribution of electricity to the development trajectory
Uganda 2020-06-04 2023-06-04 Social Science and Humanities Degree Award
FREDRICK MAKUMBI
ID:
Performance Monitoring for Action (PMA) Uganda
REFNo: HS625ES

General objective
To monitor change in contraceptive availability and use in Uganda and increase understanding of the factors contributing to that change through panel surveys in order to support FP program monitoring and improve performance.

Specific objectives
Specifically, the project aims to conduct cross-sectional and panel surveys at the female, household, and service delivery levels, with a focus on actionable programmatic data on contraceptive availability and use dynamics in targeted geographic areas in order:
1. To measure and monitor key family planning indicators of programmatic relevance cross-sectionally on an annual basis including contraceptive prevalence rate and stocks of contraceptive commodities in Service Delivery Points serving the Enumeration Areas
2. To assess the determinants and consequences of contraceptive availability and use dynamics in Uganda.
3. To evaluate factors associated with a change in contraceptive use states including: Contraceptive acceptor (non-user to user), Contraceptive discontinuer (user to non-user), and Contraceptive switcher (user of one method to a different method)

Uganda 2020-06-04 2023-06-04 Medical and Health Sciences Non-degree Award
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