Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Anise Gold-Watts
ID: UNCST-2024-R003192
Impact Assessment of Plan International\'s Girls Get Equal multi-country program to prevent early/forced marriage
REFNo: SS3264ES

To assess how the GGE has affected the conditions of adolescent girls, boys and their families in the programming areas.,To assess the program’s effects on society and how the program has contributed to reduced levels of child, early and forced marriage in the program areas.,
USA 2024-10-18 15:22:17 2027-10-18 Social Science and Humanities Non-Clinical Trial Non-degree Award
Emily Rubooga Kaakyo
ID: UNCST-2024-R002702
The Path of Least Resistance: A Qualitative Exploration of Economic/Financial Abuse of Upper and Middle-Class Women in Uganda.
REFNo: SS3322ES

Domestic abuse is often framed in terms of physical violence, which often overlooks non-physical forms of abuse, such as economic or financial abuse. This research focuses on the dominant framing of domestic abuse as primarily physical violence and examines how this framing affects the recognition and response to economic/financial abuse, particularly among middle and upper-class women in Uganda. While public discourse tends to emphasize physical violence, this study seeks to expand the understanding of more subtle, yet potentially more damaging, forms of non-physical abuse like economic violence. The effects of non-physical forms often manifest over time, making it harder to link cause and effect, unlike the more immediate impacts of physical violence. Through a qualitative approach that combines in-depth interviews, key informant interviews, and discourse analysis, the study aims to illuminate how framing influences the recognition of, and responses to, economic/financial abuse. The research is grounded in an applied behavioral lens and draws on Daniel Little’s “microfoundations” approach, which emphasizes the importance of understanding individual behaviors and decisions as foundational to broader social phenomena. By focusing on micro-level foundations, this research explores how individuals’ interpretations of domestic abuse shape their responses to economic/financial abuse. This study focuses on upper and middle-class women—by deliberately selecting deviant or outlier cases that challenge traditional theories, we aim to uncover new causal variables or mechanisms that have been previously overlooked, particularly in relation to how domestic violence is framed primarily as physical, leading to the under-recognition of economic violence. This narrow view may be contributing to the rising incidence of violence against women and children in Uganda. This thesis challenges conventional prevention strategies by calling for the creation of social mandates that address the underlying conditions and “contextual opportunities” that enable abusive behaviors. Drawing on social disorganization theory, the study seeks to highlight the far-reaching effects of economic/financial abuse on community cohesion and social control, ultimately contributing to a more nuanced understanding of domestic abuse and promoting more holistic approaches to its prevention and accountability. Specific Objectives: Identify patterns, perceptions, and narratives surrounding economic/financial abuse among middle and upper-class women, to understand the personal and broader societal impact of this form of abuse. Examine the alignment or divergence between these women’s experiences and dominant public discourse on domestic abuse, particularly regarding the recognition of economic/financial abuse. Analyze how the framing of domestic abuse influences the perceptions and responses of professionals and community members toward economic/financial abuse. Explore strategies for reframing domestic abuse, aiming to make economic/financial abuse more salient and recognized in both policy and practice. Propose actionable measures to strengthen community accountability in preventing domestic abuse by incorporating economic/financial abuse into the broader understanding of domestic violence.
Uganda 2024-10-16 21:44:29 2027-10-16 Social Science and Humanities Non-Clinical Trial Degree Award
Ronald  Jjagwe
ID: UNCST-2024-R002922
A SITUATIONAL ANALYSIS ON THE EFFECTIVENESS OF TECHNOLOGY TRANSFER SYSTEMS IN UGANDA
REFNo: SIR395ES

The overall objective of the study is to analyse the ability of technology transfer systems to facilitate technology dissemination in Uganda. The specific objectives of the study are to: i) identify and map key actors in the technology transfer systems in Uganda; ii) determine the modes of technology transfer that exist in Uganda; iii) assess the effectiveness of technology transfer systems in Uganda and; iv) identify the strengths, weaknesses, opportunities and threats in technology transfer systems in Uganda.
Uganda 2024-10-16 21:33:10 2027-10-16 Engineering and Technology Non-Clinical Trial Non-degree Award
Asiati Mbabazi
ID: UNCST-2024-R005004
PERFORMANCE APPRAISAL, MOTIVATION AND TEACHERS' JOB PERFORMANCE IN SECONDARY SCHOOLS IN UGANDA: A CASE OF KASESE DISTRICT.
REFNo: SS2891ES

To establish the effect of motivation on teachers’ job performance in secondary schools in Kasese District.,To investigate the influence of performance review on teachers’ job performance in secondary schools in Kasese District,To determine the role of performance monitoring in teachers’ job performance in secondary schools in Kasese District,To assess the relationship between performance planning and teachers’ job performance in secondary schools in Kasese District,The purpose of this study is to examine the influence of performance appraisal, motivation on teachers’ job performance in secondary Schools, Kesese District, Uganda, in order to improve teacher productivity and students’ performance.,
Uganda 2024-10-15 9:00:31 2027-10-15 Social Science and Humanities Non-Clinical Trial Degree Award
Elizabeth namukwaya namukwaya
ID: UNCST-2021-R013177
Supporting undergraduate nurses palliative care education needs
REFNo: HS4672ES

To identify areas for reciprocal learning and shared learning priorities between these countries,To examine student nurses and educators experiences of palliative care education,To generate understanding of undergraduate palliative care nursing education in South Africa, Uganda, Ghana, New Zealand, Canada and the UK,
Uganda 2024-10-14 8:15:25 2027-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nixon Niyonzima
ID: UNCST-2020-R014577
A Phase III, Randomized, Double-Blind, Placebo-Controlled Study Evaluating Atezolizumab and Bevacizumab, with or without Tiragolumab, in Patients with Untreated Locally Advanced or Metastatic Hepatocellular Carcinoma (IMBRAVE152)
REFNo: HS5026ES

To evaluate the immune response to tiragolumab and atezolizumab,To characterize the PK profile of atezolizumab plus bevacizumab plus tiragolumab, To evaluate the safety of atezolizumab plus bevacizumab plus tiragolumab compared with atezolizumab plus bevacizumab,To evaluate the efficacy of atezolizumab plus bevacizumab plus tiragolumab compared with atezolizumab plus bevacizumab,
Uganda 2024-10-14 8:13:47 2027-10-14 Medical and Health Sciences Clinical Trial Non-degree Award
Isaac Ebiju
ID: UNCST-2024-R003903
Assessing the Impact of Summary Clinical Guidelines (charts and wheels) on Rational Antibiotic Use and Compliance with Uganda Clinical Guidelines Among Outpatient Prescribers: A case study of Health Centres III & IV in Kampala, Uganda.
REFNo: HS4926ES

To assess the impact and sustainability of summary clinical guidelines for improving compliance of prescription patterns with treatment guidelines on antibiotic use among prescribers at health Centers III and IV in Kampala, Uganda.,To analyze factors affecting guideline utilization among prescribers at health Centers III and IV in Kampala, Uganda.,To assess the compliance and prescription patterns of the Uganda Clinical Guidelines by prescribers at health Centers III and IV in Kampala, Uganda. ,To determine if the use of summary clinical guidelines improves the rational use of antibiotics and adherence to Uganda clinical guidelines among prescribers in outpatient departments of Health Centre IIIs and IVs in Kampala, Uganda.,
Uganda 2024-10-14 8:08:10 2027-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Thereza Piloya Were
ID: UNCST-2019-R000491
Effects of Social Determinants of Health on Type 1 Diabetes (T1D) Care in Sub Saharan Africa; Perspectives from Uganda.
REFNo: HS5008ES

Primary
i. To describe the SDOH among the children and youths in Uganda.
ii. To determine the impact of SDoH on glycemic control of children and youths aged 6 months- 25 years in Uganda.
iii. To determine the effect of the SDoH on the physical growth of children and youths in Uganda.
Secondary
i. To set up a database of SDoH for children with T1D in Uganda.
ii. To determine the effect of the SDoH on the complications (DKA, severe hypoglycemia and hypertension) of children and youths in Uganda.

Uganda 2024-10-14 8:06:50 2027-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Cissy  Kityo
ID: UNCST-2021-R013663
Impact of Non-B HIV-1 Subtype on second-line Protease Inhibitor Regimens in Africa (INSPIRE)
REFNo: HS5035ES

To evaluate the effect of replicative fitness on susceptibility to PIs in patients with repeated failure in presence of known and novel Gag and Env PI-associated mutations.,To assess HIV-1 drug resistance in PI-resistant viruses using phenotypic drug susceptibility assay and recombinant viruses based on gag, pol, and env genes derived from patients failing 2L.,To determine the basis for second line (2L) treatment failures on ATV/r- and LPV/r-containing regimens in the absence and presence of protease-associated drug resistance.,To determine the effect of Non-B HIV-1 Subtype on second-line Protease Inhibitor Regimens in Africa.,
Uganda 2024-10-14 8:03:22 2027-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Benjamin Eyre
ID: UNCST-2024-R002750
Enumerating development: how interdisciplinary perspectives on the treatment of research officers can improve data for social transformation
REFNo: SS3327ES

To generate new knowledge on FOs perspectives in relation to their work practices and conditions with a particular focus on how they see this affecting the quality of the data they produce. ,To explore challenges FOs negotiate, including low salaries, precarious employment contracts, pressure to perform quickly, working in dangerous environments, and negotiating knowledge hierarchies.,To document the lived experience of FOs working in the behavioural economics research sector in Uganda. Their work involves conducting surveys, experiments, and RCTs in informal urban settlements, peri-urban, and rural areas. ,
UK 2024-10-14 8:02:17 2027-10-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
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