WINTERS MUTTAMBA
ID:
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Exacerbation of Chronic Bronchial Sepsis (ECBS): A study of the role of key bacteria in exacerbations of COPD and bronchiectasis
REFNo: HS921ES
SECONDARY OBJECTIVES
i. To compare bacterial loads at presentation with time to first exacerbation.
ii. To assess the relationship of bacterial loads of specific bacteria with emergency attendance.
iii. To compare bacterial loads at presentation with time-to-clinical-stability (TCS), CRP response and length of antibiotics.
iv. To assess the relationship of specific bacterial loads with quality of life (QoL) scores.
v. To assess the microbiome dynamics during- and after- treatment.
EXPLORATORY OBJECTIVES
1. To compare bacterial loads with Bronchiectasis Severity Index (BSI) in those with a clinical diagnosis of bronchiectasis.
2. To compare admission bacterial loads with baseline FEV for relationship with key clinical outcomes.
3. To compare key clinical outcomes based upon initial counts of neutrophils, lymphocytes, platelets and eosinophils, and their ratios (including principally neutrophil-lymphocyte ratio, NLR, and platelet-lymphocyte ratio, PLR).
4. To compare bacterial loads with bronchiectasis severity index (BSI) in those with a clinical diagnosis of bronchiectasis.
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Uganda |
2020-11-26 |
2023-11-26 |
Medical and Health Sciences |
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Non-degree Award |
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Elizeus Rutebemberwa
ID: UNCST-2022-R009070
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Reducing Tobacco use among the In- and Out-of-School youths in Moroto district, Uganda
REFNo: HS1021ES
General objective:
The general objective is to assess tobacco use among the youth in Moroto district.
Specific objectives:
1)Explore perceptions of tobacco use among youth in and out of school in Moroto district
2)Determine the factors associated with tobacco use among youth in and out of school in Moroto district
3)Describe the perceptions regarding tobacco use among the school teachers and administrators
4)Explore the cultural role that tobacco use plays in the lives of the youth in Moroto district.
5)Assess adherence to the tobacco control Act within bars and restaurants in Moroto district.
6)Assess youth access to tobacco in Moroto district.
7)Describe the perception of the implementation of tobacco control activities in Moroto district by enforcement officers.
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Uganda |
2020-11-26 |
2023-11-26 |
Medical and Health Sciences |
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Non-degree Award |
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Shaheen Memon Mohamed Zahiruddin
ID:
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APPLICATION OF MACHINE LEARNING TECHNIQUES TO ANTENATAL ATTENDANCE, MATERNAL MORBIDITY AND FETAL OUTCOMES IN UGANDA
REFNo: HS977ES
1. Establish the factors associated with the number of ANC visits by a pregnant woman who experiences SMM in Uganda.
2. Examine the factors associated with severe maternal morbidity as experienced by pregnant women in Uganda.
3. Assess the maternal factors associated with negative fetal outcomes in Uganda.
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Kenya |
2020-11-26 |
2023-11-26 |
Medical and Health Sciences |
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Degree Award |
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Harriet Opondo
ID: UNCST-2022-R010927
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Counselors’ Experiences of HIV Status Disclosure to Children living with HIV in Uganda
REFNo: SS626ES
-To explore subjective experiences of counselors during the process of status disclosure to children living with HIV
-To find out how counselors are prepared and trained to conduct status disclosure to children living with HIV.
-To establish the current interventions used by counselors in HIV disclosure process to children.
-To find out self-identified training needs of counselors during and after status disclosure to children living with HIV.
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Uganda |
2020-11-26 |
2023-11-26 |
Social Science and Humanities |
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Degree Award |
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Fred Ssewamala
ID: UNCST-2020-R014060
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Suubi4Stigma: Addressing HIV-Associated Stigma Among Adolescents
REFNo: SS632ES
Suubi4Stigma will address the urgent need for theoretically and empirically informed interventions that seek to reduce HIV/AIDS-associated stigma and its negative impact on child health and psychosocial well-being. Specifically, the proposed study will examine two evidence-based interventions used in mental health settings, schools, and communities: 1) group cognitive behavior therapy (G-CBT) focused on cognitive restructuring and strengthening coping skills at the individual level; and 2) a multiple family group (MFG) intervention that strengthens family relationships to address stigma among CLWH and their families.
Aim 1: Pilot test the feasibility, acceptability, and preliminary impact of innovative G-CBT and MFG on reducing HIV/AIDS-associated (internalized and family-level) stigma and its’ impact on youth and family-level outcomes (stigma, trauma symptoms, depression, sexual risk, family/social support and adherence to medication) compared to: 1a) usual care vs G-CBT; b) Usual care vs MFG; c) G-CBT vs. MFG;
Aim 2: Qualitatively examine participants’ and facilitators’ intervention experiences and identify individual, family and institutional-level facilitators and barriers to G-CBT and MFG intervention implementation and participation.
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Uganda |
2020-11-26 |
2023-11-26 |
Social Science and Humanities |
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Non-degree Award |
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Joseph Oloro
ID: UNCST-2024-R004525
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Toxicological study of the antimalarial remedy (Artavol®) and its flavonoid isolate from artemesia annua
REFNo: HS540ES
To determine acute toxicity of Artavol® and of its isolated flavonoids
ii. To investigate the sub-acute and sub-chronic toxicity potential of Artavol® and of its isolated flavonoids.
iii. To evaluate the effects of Artavol® and of its isolated flavonoids on the fetus.
iv. To examine the mutagenic potential of Artavol® and of its isolated flavonoids.
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Uganda |
2020-11-25 |
2023-11-25 |
Medical and Health Sciences |
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Degree Award |
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Bruce Kirenga J
ID: UNCST-2019-R001460
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Characteristics of persons screened, tested and diagnosed with corona virus disease-19 at health facilities in Uganda
REFNo: HS657ES
Main objective:
To estimate the cumulative incidence of a composite treatment outcome of admission to intensive care unit, mechanical ventilation or death among COVID-19 confirmed patients attending health facilities in Uganda for COVID-19 care.
Secondary objectives:
1. To describe the socio-demographic, behavioral and clinical characteristics of patients screened for and or receiving COVID-19 care at health facilities in Uganda
2. To determine the screening and testing outcomes of COVID-19 infections among patients at health facilities in Uganda
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Uganda |
2020-11-25 |
2023-11-25 |
Medical and Health Sciences |
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Non-degree Award |
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Jafesi Pulle
ID: UNCST-2020-R014213
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DECENTRALIZATION OF BENZATHINE PENICILLIN G BEST PRACTICES: BUILDING THE TOOLS FOR A SUSTAINABLE AND SCALABLE PROGRAM
REFNo: HS835ES
(1) Develop materials that can be used across Uganda and East Africa to strengthen BPG administration skills in the health worker community,
(2) Test this package of materials in Lira and Mbarara, areas with high BPG demands, and
(3) Evaluate the immediate and 3-month results of the educational program on proper BPG delivery, health worker comfort, and patient satisfaction.
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Uganda |
2020-11-25 |
2023-11-25 |
Medical and Health Sciences |
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Degree Award |
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Firminus Mugumya
ID:
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Measuring the Impact and Sustainability of a Community-Based Child Protection Approach in Prevention of Violence Against Children in a Post Conflict Setting in Northern Uganda.
REFNo: SS566ES
The overall question for this evaluation is: What is the impact and sustainability of interventions to strengthen community-based child protection systems on prevention of violence against children in families and communities emerging from a protracted armed conflict?
The specific questions are:
•Does training Child Protection stakeholders result into functional community-based Child Protection systems for prevention of violence against children?
•Does an equipping child protection structure with knowledge, skills, financial and material resources on case management improve access to child protection services?
•Does legislation and dissemination of relevant child protection laws lead to improved implementation and enforcement for prevention of violence against children?
•Does equipping children with knowledge and skills in child protection, make them indispensable change agents for addressing violence against children?
•What evidence exists to show that the project interventions to prevent violence against children at family and community level in post-conflict setting will be sustainable?
•What are the critical enablers of project success, and what should be avoided for future similar interventions in and out of post-conflict settings?
•How sustainable are interventions interventions to strengthen community-based child protection systems?
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Uganda |
2020-11-25 |
2023-11-25 |
Social Science and Humanities |
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Non-degree Award |
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Ronald Mulondo Mulondo
ID:
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Spatiotempoaral Characterization of Congenital Myelomeningocele in Uganda
REFNo: HS763ES
1.To provide a basic description of the MMC dataset at CURE Hospital, characterizing the geographical and temporal distribution.
2.To examine whether the incidence of MMC in Uganda is non-uniform or not.
3.To examine the association between MMC case incidence and rainfall.
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Uganda |
2020-11-24 |
2023-11-24 |
Medical and Health Sciences |
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Degree Award |
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Benjamin Atwine
ID:
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Knowledge and risk factors of Hepatitis B disease among women attending Antenantal Care ate Arua Regional Referral Hospital, Uganda.
REFNo: HS785ES
General Objective
To determine the level of available knowledge and risk factors associated with Hepatitis B disease among pregnant women attending ANC at ARRH.
Specific Objective
1. To determine the percentage of women attending ANC at ARRH who are knowledgeable about Hepatitis B disease.
2. To determine the prevalence of Hepatitis B disease among pregnant women attending ANC at ARRH who take part in the study.
3. To determine the risk factors of Hepatitis B disease among pregnant women seeking ANC at ARRH.
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Uganda |
2020-11-24 |
2023-11-24 |
Medical and Health Sciences |
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Degree Award |
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Kenneth Ssebambulidde Ssebambulidde
ID: UNCST-2021-R013976
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Collection of control DNA samples for the AMBITION-cm host-susceptibility to cryptococcal infection sub-study (a genome wide association study). A sub-study of the AMBITION-cm Trial
REFNo: HS789ES
To identify genetic variants associated with Cryptococcal meningitis susceptibility and disease severity
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Uganda |
2020-11-24 |
2023-11-24 |
Medical and Health Sciences |
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Non-degree Award |
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Paul Kutyabami
ID: UNCST-2020-R015029
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THE EFFECT OF COVID-19 OUTBREAK ON ONGOING RESEARCH PROCESSES IN UGANDA: KEY STAKEHOLDER’S EXPERIENCES, OPINIONS AND COPING STRATEGIES
REFNo: HS910ES
1.To explore the experiences of key stakeholders involved in research during Covid-19 outbreak in Uganda
2.To explore opinions and strategies regarding conduct of research during epidemic outbreaks in Uganda.
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Uganda |
2020-11-24 |
2023-11-24 |
Medical and Health Sciences |
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Non-degree Award |
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Viola Karungi
ID:
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Critical Theatre: An Analysis of Plays Representing the concepts of Violence, Injustice and the nature of Imperialism in regard to the War (1987-2006) in Northern Uganda.
REFNo: SS605ES
The major research question for the study is:
i. How do the plays Silent Voices, Forgotten World and Forged in Fire about the war in northern Uganda contribute to understanding the role of contemporary critical theatre in light of Uganda’s history of critical theatre?
The sub-questions are:
i. How do the plays represent the concept of violence on victims of the war in northern Uganda?
ii. How do the plays expose the nature of imperialism by the donor countries and institutions from the West that gave donor and humanitarian aid during the war and in its immediate aftermath?
iii. How do the plays represent the concept of injustice and how it is shaped by violence and imperialism regarding the war in northern Uganda?
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Uganda |
2020-11-23 |
2023-11-23 |
Social Science and Humanities |
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Degree Award |
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Stella Neema
ID: UNCST-2019-R000814
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Evaluation of UNICEF’s District Health Systems Strengthening Initiative (DHSSi) – Uganda Study Protocol
REFNo: SS613ES
The overall objectives of the evaluation are twofold:
• To improve intervention design and management, and
• To inform decisions about future investment and scale-up by establishing evidence of the results and impact of the intervention.
These overall objectives are further broken down into specific objectives:
• Assess whether interventions were implemented according to the work plan and measure the strength of the implementation.
• Examine district health governance and management capacity.
• Identify key lessons learned and provide actionable and evidence-based recommendations for improvements and scale-up.
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Uganda |
2020-11-23 |
2023-11-23 |
Social Science and Humanities |
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Non-degree Award |
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DOROTHY NAKIMBUGWE NAKIMBUGWE
ID:
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Impact of COVID19 lock down and, effectiveness of supplementary feeding on the nutrition status of mothers and their malnourished breastfeeding children, attending nutrition Units of health facilities in Kampala and Wakiso – a pilot study to inform national and organizational policies and interventions
REFNo: HS984ES
a) Assess the impact of the COVID19 lockdown and social distancing requirements on the nutrition status of mothers of children attending nutrition clinics at health centers and their access to food in Kampala and Wakiso districts through individual interviews using a semi-structured questionnaire.
b) Determine the effectiveness of a locally produced nutrient-enhanced composite porridge flour for improving the nutrition status of mothers and their breastfed malnourished children.
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Uganda |
2020-11-23 |
2023-11-23 |
Medical and Health Sciences |
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Non-degree Award |
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DAVID KATEETE PATRICK
ID: UNCST-2020-R004018
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Insight into the Role of the Microbiome in Pulmonary tuberculosis in Kampala, Uganda (MTI-Plus)
REFNo: HS738ES
The overall purpose of this proposal is to determine the composition of the microbiome in pulmonary TB patients in Kampala Uganda, and its relationship with TB treatment response and immune response relative to household healthy contacts without TB and HIV-infection. In context of treatment naïve adult TB patients, we will (1) (a) Examine the relationship between sputum and gut microbiome diversity and disease. (b) Investigate the relationship between sputum and gut microbiome composition and treatment response in patients on first-line TB therapy, and whether dysbiosis resolves in patients who get cured from TB after successfully completing anti-TB therapy. (2). Investigate the relationship between sputum and gut microbiome composition and inflammatory cytokine production capacity.
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Uganda |
2020-11-20 |
2023-11-20 |
Medical and Health Sciences |
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Non-degree Award |
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Chioma Adeyemi Njideka
ID:
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Phytochemical and Abortifacient Studies of Commelina benghalensis in Wister Rats
REFNo: SS576ES
The specific objectives of this study are;
a) To profile the phytochemical groups in C. benghalensis L in rats.
b) To determine the acute toxic dose of leaves and stalk extracts of C. benghalensis L in rats.
c) To investigate the abortifacient activities of leaves and stalk extracts of C. benghalensis L in rats.
d) To evaluate the sub-acute effect of the plant extract showing more abortifacient activity in wistar rats.
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Nigeria |
2020-11-20 |
2023-11-20 |
Social Science and Humanities |
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Degree Award |
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Barbara Mukasa
ID:
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Baseline, Midterm and End of Project Evaluation Protocol for Mildmay Mubende Region
REFNo: SS639ES
(i) Systemize baseline, midterm and end of project evaluations including interim analyses for Mubende region service delivery implementing mechanism supported by CDC Uganda.
(ii) Closely monitor the progress of outputs as measured by Monitoring Evaluation and Reporting (MER) indicators arising from implementation of activities and conduct periodic program evaluations to determine the funded activities will achieve outcomes that ultimately reduce HIV incidence and AIDS
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Uganda |
2020-11-20 |
2023-11-20 |
Social Science and Humanities |
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Non-degree Award |
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Paul Kutyabami
ID: UNCST-2020-R015029
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Assessing the impact of the requirements for dual- licensing guidelines on the number of drug outlets and compliance to regulation
REFNo: HS1048ES
-To determine the trends in the number of pharmacies licensed as both retail and wholesale from 2016 to 2020 in NDA regions
-To establish the level of compliance of pharmacies previously dual-licensed as of 2016 to set requirements of their current license
-To explore the possible factors other than guidelines associated with a decline in the license application for pharmacies that have had dual licensure
-To determine the effect of dual licensing guidelines on access to medicines in underserved areas
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Uganda |
2020-11-20 |
2023-11-20 |
Medical and Health Sciences |
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Non-degree Award |
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