Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Moses Oketch
ID: UNCST-2024-R004313
Long-Term Impacts of Improved Childhood Literacy
REFNo: SS2796ES

Economic situation,
UK 2024-08-05 14:01:33 2027-08-05 Social Science and Humanities Clinical Trial Non-degree Award
Jonathan Mayito
ID: UNCST-2019-R000490
Detection of Mycobacterium tuberculosis in blood of tuberculosis patients and their contacts in Uganda
REFNo: HS4553ES

To determine whether Mtb strains isolated from the sputum/blood of index cases with pulmonary TB are genetically identical to those detected in the blood of their contacts,To establish whether detection of Mtb in blood using the methods above associates with either of the following biomarkers of host immune response: - QFT-Plus - Blood RNA signatures for incipient tuberculosis,To determine whether Mtb can be detected in the blood of TB patients and their contacts, recruited in Kampala, Uganda, using any of the following methods: - GeneXpert® MTB/RIF Ultra (Cepheid) - Fluorescence microscopy - Blood culture - Targeted Next-Generation Sequencing,The primary objective of this study is to determine whether Mtb DNA can be detected in the blood of TB patients and their contacts, recruited in Kampala, Uganda, using digital PCR,
Uganda 2024-08-05 13:49:07 2027-08-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
OKELLO DAMOI JOSEPH
ID: UNCST-2022-R011560
Construction and Validation of a Poverty Assessment Survey Tool to Inform Ambulatory Care and Surgery Cost Waiver or Subsidization in a Developing Country
REFNo: HS4463ES

To determine the weights of each attribute per item, in the constructed and validated tool that can be used to inform ambulatory care and surgery cost waiver or subsidization in a developing country,To construct a validated ambulatory care and surgery-context poverty assessment survey tool that can be used to inform ambulatory care and surgery cost waiver or subsidization in a developing country,To analyze the data earlier collected using the ambulatory care and surgery-context poverty assessment survey tool at KSC, for principal components,To conduct content validity and reliability testing of the ambulatory care and surgery- context poverty assessment survey tool, previously developed with adaption of some items from the simple poverty score tool for Uganda,To construct and validation of a poverty assessment survey tool that can be used to inform ambulatory care and surgery cost waiver or subsidization in a developing country,
Uganda 2024-08-05 13:12:56 2027-08-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Vesall Nourani
ID: UNCST-2022-R009221
Impact of on-demand irrigation service : Evidence from Uganda
REFNo: SS2112ES

Do certain intermediaries (providers of agricultural inputs) facilitate efficient information aggregation and dissemination of farming knowledge between farmers?,
USA 2024-08-05 13:11:25 2027-08-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Lawrence Okidi
ID:
NUTRITIONAL QUALITY AND MICROBIAL SAFETY OF SELECTED INDIGENOUS FOODS FOR CHILDREN UNDER FIVE: A CASE STUDY OF KARAMOJA SUB-REGION OF UGANDA
REFNo: A51ES

1.3 Objectives
1.3.1 General objective
To contribute to food security by investigating the nutritive quality and safety of indigenous foods for children under five in Karamoja sub-region.
1.3.2 Specific objectives
i. To assess household handling practices of selected indigenous foods for children under five in Karamoja sub-region
ii. To determine the nutritional quality of selected indigenous foods for children under five in Karamoja sub-region
iii. To determine the microbial load and diversity of selected indigenous foods for children under five in Karamoja sub-region
iv. To determine the dietary exposure risk of children under five to pathogenic microorganisms from selected indigenous foods in Karamoja sub-region

Uganda 2024-08-02 17:46:01 2027-08-02 Agricultural Sciences Degree Award
Charles Masembe Kikubo
ID: UNCST-2019-R001092
Investigating the dynamics and clinical outcome of African swine fever infection at pig farms in an endemic livestock wildlife setting in Uganda
REFNo: A355ES

1) Assess the spatial distribution of pig farmers in the study areas and recruit them
2) Determine the ASF virus molecular characteristics in apparently healthy domestic pigs
3) Determine the genetic characteristics and relationships of ASFV isolated from domestic pigs
4) Determine the full genome characteristics of the unique lineages obtained from domestic pigs
5) To establish an ASF biobank of clinical materials that are curated with clinical outcomes
6) Establish Ugandan Genotype IX repository at PIADC - for genomics and vaccine research
7) Build rapid ASF whole genome sequencing capacity in endemic settings

Uganda 2024-08-01 16:54:11 2027-08-01 Agricultural Sciences Non-Clinical Trial Non-degree Award
David Kibirige
ID:
DESIGN AND IMPLEMENTATION OF A PV SYSTEM FOR EMERGENCY SITUATION IN HEALTH FACILITIES IN RWEBISENGO UGANDA
REFNo: SIR363ES

4. To carryout hardware design and field test of the PV system,3. To design an improved inverter system for both AC single phase and three phase for PV application.,2. To model a PV power system circuit using Proteus software as well as carrying out its dynamic modeling using Simulink,1. To carry out Electrical and thermal analysis of a PV system to be used during the study,The aim of this research is to design a PV system that can be utilized during emergency situation in health facilities in Rwebisengo Uganda.,
Uganda 2024-08-01 16:05:23 2027-08-01 Engineering and Technology Non-Clinical Trial Degree Award
EDWINAH ATUSINGWIZE
ID: UNCST-2023-R007893
Exploring Stakeholder perspectives of the social determinants of malaria in Uganda
REFNo: HS4271ES

3. To explore barriers and facilitators to addressing the social determinants of malaria.,2. To examine how the social determinants of malaria are addressed in policy making and practice. ,1. To explore stakeholder perspectives of the social determinants of malaria.,The overall aim of this study is to explore stakeholder perspectives and experiences of the social determinants of malaria in Uganda in order to inform malaria prevention policy and practice. ,
Uganda 2024-07-26 16:04:20 2027-07-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Alen Musisi
ID: UNCST-2022-R009338
Knowledge, Attitude, and Practice on Radiation Protection Among Radiation Safety Officers in Uganda.
REFNo: HS4617ES

To determine the radiation protection knowledge level among RSOs
To determine the level of attitudes of RSOs towards radiation protection and safety
To determine radiation protection practices among RSOs

Uganda 2024-07-26 16:03:08 2027-07-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jean Damascene Niyonsenga
ID:
Role of PT in Ugandan Neurosurgical Transitional Care
REFNo: HS4400ES

This study aims to determine acceptability and feasibility of utilizing an interdisciplinary discharge planning protocol to improve team communication and increase patient referral to outpatient rehabilitation services in two public Ugandan hospitals.
Rwanda 2024-07-26 16:01:48 2027-07-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mbisi Muhindo Enosh
ID:
HOST COMMUNITIES’ RELATIONS AND REFUGEE ADAPTABILITY AT KYAKA II AND KYANGWALI SETTLEMENTS IN WESTERN UGANDA
REFNo: SS2953ES

To examine the role of social cohesion within host communities in facilitating refugee adaptability at Kyaka II and Kyangwali settlements,To investigate how Attitudes and Perceptions of host communities influence Refugee Adaptability at Kyaka II and Kyangwali settlements,To assess the socio-economic and political factors contributing to refugee adaptability at Kyaka II and Kyangwali settlements,To examine the impact of legal and policy framework on Refugee Adaptability within Host communities at Kyaka II and Kyangwali settlements in Uganda,To examine the dynamics and factors influencing the relationship between host communities and refugees, and to understand the impact of this relationship on the adaptability and integration of refugees at Kyaka II and Kyangwali settlements,
Uganda 2024-07-26 15:59:56 2027-07-26 Social Science and Humanities Non-Clinical Trial Degree Award
Doris Kwesiga
ID:
Implementer’s Voices: An input to the Lancet Commission on Evidence-based Implementation in Global Health
REFNo: HS4408ES

To examine the insights and experiences of LMIC health sector implementers on the use of evidence in their work, so as to identify barriers and enablers and design interventions to increase evidence-based implementation.,ii. What are the gaps between evidence and implementation, and how can these be closed?,i. How and why, do (or don’t) implementers use evidence? ,
Uganda 2024-07-26 15:58:42 2027-07-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ismail  Draguma Legason
ID: UNCST-2021-R012130
Molecular profiling of Epstein-Barr virus genome and expression in endemic Burkitt Lymphoma (EBVL study)
REFNo: HS4198ES

1. The main goal of the study is to examine the molecular architecture of EBV, its expression pattern, and the determinants of viral pathogenesis in endemic Burkitt lymphoma. ,Perform differential gene expression and protein analysis on formalin fixed-paraffin embedded BL tissues using RT- PCR or NanoString and analyse the data for: i) differentially expressed genes and proteins ii) gene and protein expression levels iii) correlation with tumour stage and viral strains ,Perform whole genome sequencing of EBV from clinical samples (ctDNA for eBL and plasma for healthy controls) and analyse data for: i) viral strains and co-infection ii) Mutations (SNVs, Indels, and structural variants) and compare frequencies iii) mutational signatures iv) viral population structure -phylogenetics and decomposition matrices to infer evolutionary relatedness with publicly available strains. ,
Uganda 2024-07-26 15:56:08 2027-07-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Sarah  Mayanja
ID:
Effect of the Triple S technology on farmers' food security in northern and eastern Uganda
REFNo: A438ES

3. To compare the extent to which sweetpotato augments smallholder’s food availability amongst users and non-users of the Triple S technology ,2. To assess the values which motivate use and uptake of the Triple S technology by smallholder farmers,1. To compare the Knowledge, Attitudes and Perceptions towards the Triple S technology by users and non-users of the technology ,Overall objective: To assess the contribution of the ‘Triple S’ technology on farmers food security in the northern and eastern regions of Uganda.,
Uganda 2024-07-26 15:54:12 2027-07-26 Agricultural Sciences Non-Clinical Trial Degree Award
Adam Lichtenheld
ID: UNCST-2024-R004326
Re:Build – Building Business and Social Networks to Strengthen Refugee Economic and Social Integration
REFNo: SS2803ES

The effect of the intervention on approaches of collaboration and information sharing,The effect of the intervention on psychological and social dimensions for each individual,The effect of the intervention on business outcomes (profit, savings, business growth),The effect of the intervention on network constellations in participants’ egocentric business networks,1. How can interventions support the development of business networks for refugees and nationals in urban markets of developing countries? ,
USA 2024-07-26 15:50:47 2027-07-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Grace Kaweesa
ID:
THE EFFICACY OF BIOCHAR AND VERMICOMPOSTS INTEGRATED WITH NPK BLENDED FERTILIZER ON SOIL BIOCHEMICAL PROPERTIES, NUTRIENT USE EFFICIENCY, YIELD AND GRAIN QUALITY OF UPLAND RICE (Oryza Sativa L.) IN CENTRAL UGANDA
REFNo: A447ES

To contribute to improved food security by increasing upland rice yields through optimizing fertilizer use efficiency using biochar and vermicomposts in central Ugandai. To ascertain the effect of Biochar and the different rates of NPK blended fertilizers integrated with VCs on growth and yield of upland riceii. To ascertain the effect of Biochar and the different rates of NPK blended fertilizers integrated with diverse VCs on selected soil biochemical properties. iii. To ascertain the effect of Biochar and the different rates of NPK blended fertilizers integrated with diverse VCs on nitrogen and phosphorus use efficiencies and uptakes in upland rice productioniv. To ascertain the effect of biochar and different rates of NPK blended fertilizers integrated with diverse VCs on selected nutritional qualities of upland rice grains.
Uganda 2024-07-26 15:48:47 2027-07-26 Agricultural Sciences Non-Clinical Trial Degree Award
Sarah Kiguli
ID: UNCST-2021-R013020
In-Hospital Mortality Among Sickle-Cell Disease Patients with and without SARS-CoV-2 co-Infection at Mulago National referral Hospital.
REFNo: HS4253ES

Genral OBJECTIVE
The overall objective of this study is to determine the in-hospital annual mortality rate among SCD patients over the 2010 to 2022 13 years period, and the association with SARS-CoV-2 infection-related morbidity and mortality in Uganda.

SPECIFIC OBJECTIVES
1.To determine prevalent SCD events and time-trend (annual) of in-hospital mortality rate before the COVID-19 pandemic (2010 to 20190) at Mulago National referral & Teaching Hospital
2. To assess probable-cause of death by adjudicating the diagnosis made at the time of death
3. To investigate the individual and health system factors (e.g., pediatricians with SCD expertise, pediatric ICU, oxygen supply, blood bank, and access to Hydroxyurea) associated with in-hospital mortality
4. To assess the prevalence of SARS-CoV-2 infection and any bidirectional effect between SARS-CoV-2 and SCD on mortality among those with vs. without SARS-CoV-2 or SCD admitted in hospital between 2020 and 2022.


Uganda 2024-07-26 15:47:47 2027-07-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Edgar Mulogo Mugema
ID: UNCST-2023-R008170
Leveraging Molecular Technologies to Improve Diagnosis and Management of Pediatric Acute Respiratory Illness in Resource-Constrained Settings.
REFNo: HS4539ES

Refine existing host immune response classifiers for the differentiation of bacterial and viral causes of febrile ARI among children in Uganda. Determine the etiology of febrile ARI episodes using a diagnostic assessment that includes physician adjudication and is augmented by pathogen metagenomics. Develop and internally validate a host immune response signature that differentiates between causes of pediatric ARI in Uganda using previously identified gene transcripts. Develop novel clinical algorithms for pediatric ARI to inform antibiotic treatment decisions ,The objective of this proposal is to develop novel clinical algorithms for pediatric febrile ARI in sub-Saharan Africa to identify children with bacterial illness. To augment samples collected during a previous cohort study (MUST REC 14/03-19) to achieve sufficient sample size to develop a host gene expression signature that differentiates between viral and bacterial ARI, we will enroll 160 children presenting to St. Pauls Health Center IV with ARI and 20 healthy controls.,
Uganda 2024-07-26 15:44:44 2027-07-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Stephen Okoboi
ID: UNCST-2019-R001356
UNDERSTANDING DRIVERS OF TB AND MALARIA PREVALENCE AND INCIDENCE, AND BARRIERS TO UPTAKE OF HEALTH SERVICES AND RETENTION IN CARE – COMMUNITY VOICE PERSPECTIVE IN NAMAYINGO DISTRICT
REFNo: SS2915ES

To collaboratively develop recommendations for driving sustainable impact and improving health outcomes in the context of TB and malaria.,To identify community-specific needs and gaps in current TB and malaria interventions and healthcare delivery systems.,To explore the socio-economic, cultural, and behavioral factors influencing the spread and persistence of TB and malaria within communities.,To engage directly with community members to understand their perspectives on the barriers and drivers of TB and malaria prevalence and incidence.,To understand the drivers of TB and malaria prevalence and incidence, as well as barriers to the uptake of health services and retention in care from a community voice perspective in Namayingo district,
Uganda 2024-07-26 15:43:11 2027-07-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
William  Veness Andrew
ID:
Assessing Causal Processes of Multi-Hazard Risk in the Rwenzori Region
REFNo: NS842ES

Generation of an evidence base for solutions through a multi-hazard risk assessment inthe Rwenzori Mountains
Hydrological characterisation of the highlands
Evidencing the mechanisms of landslides and potential for vegetative stabilisation
Evidencing geomorphological changes in river valleys
Assessment of whether water quality is being impacted by soil erosion
UK 2024-07-26 15:42:01 2027-07-26 Natural Sciences Non-Clinical Trial Degree Award
Ronald Angupale Jimmy
ID:
Design, Development and Characterization of Drug Delivery Systems for Ugandan Antimalarial Plants - Artemisia annua, Vernonia amygdalina and Microglossa pyrifolia
REFNo: HS1886ES

4. To optimize the developed drug delivery system(s) with respect to the critical product quality attributes and assess their antimalarial efficacy and safety,3. To design and develop suitable herbal drug delivery systems (conventional and novel) for the plant extracts,2. To carry out preformulation studies (physicochemical properties) for the plant extracts,1. To determine in vivo antimalarial efficacy of selected combinations of A. annua, V. amygdalina and M. pyrifolia ,To design, develop and characterize drug delivery systems for selected Ugandan antimalarial plants – Artemisia annua, Vernonia amygdalina and Microglossa pyrifolia,
Uganda 2024-07-26 13:50:14 2027-07-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Jenny Löfgren
ID: UNCST-2024-R005428
Outcomes of paediatric inguinal hernia repair performed by surgeons versus medical officers
REFNo: HS4508ES

Calculate and compare costs and cost-effectiveness between the two groups. ,Compare patient related outcomes between the group that has been operated on by medical officers versus those who were operated by general surgeons. ,The general objective of the proposed study is to investigate the possibility of task sharing between general surgeons and medical officers in inguinal hernia repair in children in Uganda. ,
Sweden 2024-07-23 15:30:50 2027-07-23 Medical and Health Sciences Clinical Trial Degree Award
Immaculate  Atukunda
ID: UNCST-2021-R013573
EVALUATION OF A NEW LOW-COST APPLANATION TONOMETER (NEWTON) IN UGANDA
REFNo: HS3998ES

To evaluate the acceptability of the use of Newton to measure IOP in patients by different eye care workers.,To evaluate the acceptability of the use of Newton to measure IOP by patients,To evaluate agreement between IOPs from the Newton versus two other established tonometers (Goldmann applanation tonometer (GAT) and iCare).,To determine the specificity and sensitivity of Newton in measuring IOP versus Goldmann applanation tonometer (GAT) as the gold standard.,
Uganda 2024-07-23 14:44:42 2027-07-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
John ILUNGOLE Stephen
ID:
EVALUATION OF THE EFFECTIVENESS OF UMEME WUUYO CAMPAIGN AGAINST POWER THEFT IN UGANDA
REFNo: SIR339ES

ii. To find out whether the public received the messages used in the Wuuyo communications campaign against power theft. ,i. To assess the effectiveness of campaign messages used in the Wuuyo campaign against power theft. ,To assess whether the Umeme Wuuyo Communications Campaign against power theft in Uganda was successful.,
Uganda 2024-07-22 17:18:00 2027-07-22 Engineering and Technology Non-Clinical Trial Degree Award
LAKER SCOVIA
ID: UNCST-2023-R006650
Antioxidants and Nutritional Potential of Enriched Millet Based Composite Flour Using Spirulina (Arthrospira platensis)
REFNo: A432ES

The objectives will be to; 1. determine the proximate composition (moisture content, ash content, fiber content and protein content) in non-germinated and germinated millet flours of eight selected local millet varieties (Ekwangapel, Ekaama, Emoro moru, Ayuku manyige, Odyera, Min bel, Luk caa and Adyang adyang). 2. determine the concentration of minerals (zinc, calcium, magnesium and iron) in non-germinated and germinated millet flours of eight selected local millet varieties (Ekwangapel, Ekaama, Emoro moru, Ayuku manyige, Odyera, Min bel, Luk caa and Adyang adyang). 3. determine the concentration of anti-nutritional factors (oxalates, tannins and Phytates) in non-germinated and germinated millet flours of eight selected local millet varieties (Ekwangapel, Ekaama, Emoro moru, Ayuku manyige, Odyera, Min bel, Luk caa and Adyang adyang). 4. determine the antioxidant potential (Beta carotene) in spirulina powder and germinated millet composite flours of three selected local millet superiors. 5. determine the consumer acceptability of the spirulina millet-based product (porridge) of three selected local millet superiors.
Uganda 2024-07-22 17:15:54 2027-07-22 Agricultural Sciences Non-Clinical Trial Degree Award
Alex Ario Riolexus
ID:
Surveillance System Performance, Timeliness Metrics and Framework of Response to Anthrax Outbreaks in Uganda: Implications for Programming and Control of Zoonotic Diseases Epidemics
REFNo: HS4277ES

4- Develop a One Health Model response framework for zoonotic disease outbreaks,3- Examine timeliness of response to anthrax outbreaks in Uganda for the period 2014 to 2023 and compare with 7:1:7 as a metric for strengthening response and improving systems in real time,2- Assess the human and animal anthrax surveillance system functions and attributes in Uganda,1- Identify gaps in epidemiological investigations of anthrax outbreaks in Africa for the period 2014 to 2023,The general objective of this study is to assess performance of the surveillance system and timeliness of response to anthrax outbreaks in Uganda, 2014 - 2023.,
Uganda 2024-07-22 17:13:33 2027-07-22 Medical and Health Sciences Non-Clinical Trial Degree Award
Swaibu Zziwa
ID: UNCST-2022-R011017
MOBILITY RECOVERY AFTER A LOWER LIMB BONE FRACTURE; EFFECTS OF A MULTI- COMPONENT HOME BASED REHABILITATION PROGRAM ON MOBILITY RECOVERY IN GREATER KAMPALA, UGANDA
REFNo: HS4641ES

1.To describe the type of care received by patients with lower limb fractures after hospital discharge in Greater Kampala, Uganda. 2.To determine mobility recovery and predictors of mobility recovery among patients with lower limb bone fractures in Greater Kampala, Uganda. 3.To develop and validate a multi component home based rehabilitation program to improve mobility recovery among patients with lower limb bone fractures in Greater Kampala, Uganda. 4.To evaluate the effect of a multi component home based rehabilitation program on mobility recovery among patients with lower limb bone fractures in Greater Kampala, Uganda.
Uganda 2024-07-22 17:09:51 2027-07-22 Medical and Health Sciences Non-Clinical Trial Degree Award
AKANKWASA JOHNSON
ID: UNCST-2023-R006429
Factors Associated with Home Based Care Services in the Control of Covid - 19 Infection in Sheema Municipality, Sheema District
REFNo: SS2402ES

3.To establish the existing, new policies and practices about home based care agencies that addressed challenges resulting from the COVID-19 pandemic in the 3 years of the peak pandemic.,2. To establish the social demographic, social economic and environmental factors that affected home based care services (HBC) in all the COVID-19 suspects during 2019 pandemic.,1. To investigate the level of utilization of Home Based Care services (HBC) in percentages among the isolated COVID-19 suspects in the control of COVID-19 infection in Sheema Municipality from 2020 to 2023.,To establish factors associated with Home Based Care Services (HBC) during COVID -19 infection in Sheema Municipality, Sheema District.,
Uganda 2024-07-22 17:06:47 2027-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
Mathias Seviiri
ID:
Genetics of Glaucoma in High-risk Diverse Populations (GoGLAD) Study
REFNo: HS3427ES

General objective
To apply and critically evaluate the efficacy of genetic-based risk prediction models for glaucoma in an understudied, high-risk, genetically diverse continental African population in Uganda.

Specific objectives
1. To test the feasibility of collecting quality pilot clinical data on glaucoma related phenotypes, genetic data from a unique high-risk diverse population in Uganda.
2. To assess cross-ancestry genetic-based prediction of glaucoma risk in major diverse ancestry populations.
2A- To apply our current European-based genetic prediction model of glaucoma to a high-risk population of African ancestry from Uganda.
2B - To develop, and calibrate an African ancestry genetic prediction model of glaucoma and implement it in populations of European and African ancestries.
2C- To develop, model and calibrate a cross-ancestry genetic prediction model and apply it in populations of European and African ancestries.
3. To apply artificial intelligence to eye images to characterise ancestral differences in glaucoma risk and evaluate estimation of disease risk and progression.
4. To assess participants’ attitude towards genetic testing for glaucoma.

Uganda 2024-07-22 17:03:10 2027-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nura Izath
ID: UNCST-2022-R009201
Autothermo-a wearable continuous temperature measuring bracelet with a central display screen.
REFNo: HS3034ES

To assess the performance of Autothermo- a wearable continuous temperature measuring bracelet and a central display screen in comparison to the standard thermometer.,To assess the feasibility and acceptability of Autothermo among health workers and parents/caregivers of admitted neonates at Mbarara Regional Referral Hospital(MRRH).,
Uganda 2024-07-22 16:57:35 2027-07-22 Medical and Health Sciences Clinical Trial Non-degree Award
David Aderu
ID: UNCST-2023-R008280
Mainz II Pouch: A viable option for the incurable fistula in Uganda
REFNo: HS3247ES

3. To assess the quality of life of recipients of the Mainz II pouch in clients with fistula deemed incurable at SRRH from 2009 to 2018.,2. To describe sonographic characteristics of the upper urinary tract in recipients of the Mainz II pouch procedure at SRRH from 2009 to 2018.,1. To determine the biochemical profile of patients with fistula deemed incurable who have undergone Mainz II pouch procedure at SRRH from 2009 to 2018.,To evaluate the viability of the Mainz II urinary diversion for women with Fistula deemed incurable in Uganda. ,
Uganda 2024-07-22 16:53:11 2027-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Aisha Nanyiti
ID: UNCST-2021-R013489
Electric cooking in the energy transition: how much subsidization is needed?
REFNo: SS2896ES

To assess the willingness to pay for modern electronic cooking technology within the grid connected urban and peri-urban areas. To assess the effect of benchmark goods on the willingness to pay for modern electronic cooking technology. To assess the impact of information provision towards the demand for modern electronic cooking technology within the grid connected urban and peri-urban areas.
Uganda 2024-07-22 16:52:07 2027-07-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
JOSELYN RWEBEMBERA
ID: UNCST-2021-R013915
Identifying the Essential Elements of Case Managers and Peer Support Groups for Prophylaxis Adherence in Rheumatic Heart Disease” (CAMPS Plus)
REFNo: HS4346ES

Objective 1: Determine the difference in 1-year SAP adherence rates of children newly diagnosed with RHD in Uganda receiving one of two support strategies: case manager only (CM) and case manager plus peer support group (CM + PG).

Objective 2: Explore implementation determinants among case managers, participants, and participant families to inform deployment of program at scale.
Uganda 2024-07-22 16:49:34 2027-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ronald Kiguba
ID: UNCST-2019-R000844
Understanding adverse drug reactions to dolutegravir and isoniazid in people living with HIV in Uganda: incidence, risk factors, management and patient reporting
REFNo: HS3364ES

To determine the incidence, characteristics and risk factors of ADRs to DTG/ IPT in PLHIV in Uganda,To identify barriers and facilitators of using the app to report ADRs by PLHIV in Uganda,To determine the rate of ADR-reporting by PLHIV at selected ART-sites in Uganda,To implement the Med Safety app to promote ADR-reporting by PLHIV in Uganda,To identify genetic polymorphisms associated with DTG-induced weight gain and hyperglycaemia, and isoniazid-related hepatotoxicity, using the GWAS approach among PLHIV in Uganda,To investigate the prevention, monitoring, management of ADRs to DTG/ IPT in PLHIV in Uganda,
Uganda 2024-07-22 16:37:17 2027-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Elisa  Macchi
ID: UNCST-2023-R004097
Pressure to Hire, Technology Adoption, and Productivity: Experimental Evidence from Uganda
REFNo: SS2013ES

1. The project aims at contributing to several strands of the literature. First, an emerging literature
hasshown how social- and self-image concerns affect the labor market through changesin the labor
supply

2. Our evidence suggests that the reputational concerns associated to hiring and technology
adoption decisions are induced by resource-sharing practices with kin and neighbors.

3. Finally, our work links to the literature on cross-country differences in productivity. Lewis et al.
(1954) observed that developing economies have a large “traditional sector” where marginal
productivity is low and where workers may be compensated above their marginal product through
informal arrangements (see Gollin (2014) for a recent discussion). When wages do not equal
marginal product, workers may be employed in relatively less-productive tasks, resulting in
misallocations. Gollinetal
Italy 2024-07-22 16:32:03 2027-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
Patience Atuhaire
ID: UNCST-2023-R007423
TORCHES (TOXOPLASMOSIS, RUBELLA, CYTOMEGALOVIRUS, HERPES AND OTHER AGENTS LIKE SYPHILIS) and relation to Preterm Delivery and Low birth weight among pregnant women living with HIV and their babies in the IMPAACT 1077BF trial
REFNo: HS4352ES

Assess/evaluate the associations between select peripartum infections with risk of PTD and LBW, across the ART groups reported in PROMISE,assess the prevalence of select peripartum co-infections (TORCH infections) among PROMISE 1077BF women living with HIV and their HEU babies at the MU-JHU CRS in Kampala Uganda using stored plasma specimens obtained at delivery,
Uganda 2024-07-22 15:03:09 2027-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Douglas Bulafu
ID: UNCST-2021-R011774
From COVID-19 to Ebola: How did lessons on Maintaining Essential Health Services during the COVID-19 Pandemic inform the Ebola response in Uganda?
REFNo: HS4422ES

5. To compare disruption to essential health services due to COVID-19 and Ebola in Mubende and Kassanda districts of Uganda.,4. To estimate the effect (disruption) of COVID-19 and Ebola in Mubende and Kassanda districts of Uganda.,3. To explore the challenges faced during implementation of public health and social measures during the Ebola epidemic in Uganda.,2. To document how lessons from previous pandemics informed the application of public health and social measures during the Ebola epidemic in Uganda.,1. To document how lessons from previous epidemics informed the health system adaptations to ensure the continuity of essential health services during the Ebola epidemic in Uganda.,To compare disruption to essential health services during COVID-19 and the 2022 Ebola outbreak and document how lessons from the COVID-19 pandemic informed the Ebola response in Uganda to inform how to prevent and respond to future epidemics.,
Uganda 2024-07-22 15:02:01 2027-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Abbey Kato
ID:
Child art: a meaning-making mechanism for children about their gender[ed] experiences and perceptions
REFNo: SS2341ES

To interrogate children’s visual art expression as a model for gender sensitization.,To examine the gender[ed] narratives that emerge from the child art experiences and perceptions expressed in the child art.,To explore children’s experiences and perceptions of their day to day life expressed through child art.,The main objective of the study is to explore how child art can be used as a meaning-making mechanism by children to express their everyday life gender[ed] experiences and perceptions.,
Uganda 2024-07-22 14:57:37 2027-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
Daniel Mwandah Chans
ID: UNCST-2022-R008880
Antimicrobial Stewardship in Critical Care: Prevention of the Transmission of Multi-Drug Resistant Superbugs in the Intensive Care Unit of Mbarara Regional Referral Hospital (AMSICU)
REFNo: HS4682ES

6. Develop an IPC protocol for the ICU.,5. Provide training on the role of pharmacokinetics (PK) and pharmacodynamics (PD) in managing critically ill patients in order to optimize antimicrobial therapy.,4. Develop a treatment algorithm for the selection of the initial antibiotic therapy and antimicrobial therapy de-escalation in the ICU.,3. Establish the use of biomarkers for rapid identification of ICU patients with bacterial infections.,2. Document the baseline antimicrobial resistance patterns for the ICU.,1. Establish a structured antibiotic stewardship program in the ICU at MRRH involving intensivists, microbiologists, nurses, specialists, clinicians, clinical pharmacists, hospital administrators and support staff.,The overall aim of the project is to prevent transmission of multi-drug resistant (MDR) superbugs in the intensive care unit (ICU) at Mbarara Regional Referral Hospital (MRRH) through building capacity of clinicians for antimicrobial stewardship (AMS) and infection prevention and control (IPC) for improved patient outcomes,
Uganda 2024-07-22 14:52:09 2027-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
KYARIKUNDA MONICA
ID: UNCST-2023-R005922
Community Based Tourism Enterprises’ appraisal and community conservation outcomes amidst changing demographics around Bwindi Impenetrable National Park.
REFNo: SS2416ES

To determine strategic initiatives for enhancing CBTEs’ performance for better community conservation outcomes in the digital era amidst changing demographics,To explore how the changing demographics have affected the implementation and performance of CBTEs around Bwindi Impenetrable National Park,To establish the CBTEs’ performance and community attitudes’ trend towards conservation of BINP,To characterize and map the spatial and temporal distribution of community Based Tourism Enterprises around Bwindi Impenetrable National Park. ,To determine barriers and facilitators of CBTEs’ performance and resultant community conservation outcomes of Bwindi Impenetrable National Park amidst changing demographics,
Uganda 2024-07-22 14:46:50 2027-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
Patrick Kagurusi Tumusiime
ID: UNCST-2021-R012687
Baseline evaluation for Action to Scale Up Reduction of Teenage Pregnancies Among Vulnerable Girls in Eastern Uganda.
REFNo: SS2455ES

The baseline seeks to benchmark the current performance in various indicators of project in Namutumba and Bugiri districts where the project will be implemented before actual project implementation starts.
Uganda 2024-07-22 14:45:11 2027-07-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Peter Olds
ID: UNCST-2023-R006240
Burden of disease and attitudes towards cancer care among adult cancer patients in Mbarara, Uganda
REFNo: HS4303ES

Aim #1: Describing the burden of disease among patients receiving care at the adult oncology clinic at the Mbarara Regional Referral Hospital. We will conduct a retrospective chart review of all adult patients receiving care at the outpatient oncology clinic and inpatient oncology ward at the Mbarara Regional Referral Hospital between January 2019 and December 2023. We will define the burden of disease as the numbers and types of cancers of patients cared for at MRRH. We will conduct a chart review collecting data on demographics, primary diagnoses, comorbidities, treatment modalities, and outcomes. Aim #2: Qualitative understanding of patient attitudes toward cancer care, specifically in Mbarara. We will interview up to 30 patients with cancer or who have undertaken cancer care at the Mbarara Regional Referral Hospital’s Adult Cancer Clinic, and conduct semi-structured qualitative interviews with the goal being to understand their experience with cancer care in Mbarara. We will focus on understanding the role of the clinic, the physicians, and nurses in the patient’s lives and how this affects their journey through receiving cancer care.
USA 2024-07-22 14:42:30 2027-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Thereza Piloya Were
ID: UNCST-2019-R000491
Development of a Training program to improve management of Type 1 Diabetes in the school setting-The Ugandan experience
REFNo: HS4398ES

To develop a T1D training program for school staff (teachers, nurses and matrons) in Ugandan schools to support the care of children and adolescents living with T1D at school by understanding the organization of T1D care in schools and provision of knowledge to the staff.
Uganda 2024-07-22 13:21:51 2027-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mugabe Nestor
ID: UNCST-2024-R003473
Urban expansion patterns and water scarcity in Uganda: A case of Greater Kampala Metropolitan Area
REFNo: SS2817ES

i. To analyse the types of urban expansion patterns in Greater Kampala Metropolitan Area.
ii. To determine the relationship between urban expansion patterns and water scarcity in Greater Kampala Metropolitan Area.
iii. To develop an urban expansion model that can mitigate water scarcity in Greater Kampala Metropolitan Area.

Uganda 2024-07-22 12:19:06 2027-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
Nicholus Nanyeenya
ID:
Infection Prevention and Control (IPC): Profiling, Barriers, Facilitators and Effectiveness of an IPC Community-of-Practice in Central Uganda
REFNo: HS4570ES

The objectives are to;
a) Characterize the uptake of IPC measures in selected health facilities in Central Uganda
b) Explore the facilitators and barriers to the uptake of IPC measures in selected health facilities in Central Uganda
c) Determine the effectiveness of an IPC community-of-practice, using peer-to-peer mentorships in enhancing the uptake of IPC measures in Central Uganda.

Uganda 2024-07-22 12:12:29 2027-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Grace Kisitu Paul
ID: UNCST-2024-R004102
UNIVERSAL1: Pharmacokinetic study of an optimized dose ratio of dolutegravir/emtricitabine/tenofovir alafenamide fumarate: expediting a UNIVERSAL first line regimen for all children living with HIV in Africa
REFNo: HS4280ES

Primary objective:
To evaluate the pharmacokinetics and short-term safety of DTG and FTC/TAF administered to children living with HIV using a novel dose ratio

Secondary objective:
To evaluate the short-term efficacy of DTG and FTC/TAF
formulations in children using a novel dose ratio

Uganda 2024-07-19 3:45:20 2027-07-19 Medical and Health Sciences Clinical Trial Non-degree Award
Janet Nakigudde
ID: UNCST-2019-R000444
PROMOTING MENTAL HEALTH OF TEACHERS AND CAREGIVERS USING A PERSONALIZED MHEALTH TOOLKIT IN UGANDA
REFNo: HS4431ES

3. To examine feasibility of mWEL-T and mWEL-P with parents and teachers from urban and rural regions (including examining feasibility of the implementation procedures and intervention efficacy) (n=160, 80 parents and 80 teachers from urban and rural regions).,To conduct a user-centered testing study to optimize usability of the Teacher and Parent versions of mWEL- mWEL-T and mWEL-P,1. To build a school system capacity (by establishing a cross-discipline digital health leadership & learning collaborative (n=10) and training a group of peer-community health workers (P-CHW) (n=30; 15 peer teachers and 15 peer parents) to implement the mWEL that is developed,The aim of the study is to test mWEL a newly developed mobile app and user-engagement strategies for mental health management and promotion targeting teachers and parents,
Uganda 2024-07-17 14:03:01 2027-07-17 Medical and Health Sciences Clinical Trial Non-degree Award
Emmanuel Musisi
ID: UNCST-2020-R004472
Assessing feasibility, acceptability and utility of Tuberculosis-Molecular Bacterial Load Assay for monitoring TB treatment in three HIV clinics in Kampala
REFNo: HS4475ES

iii. To innovate and describe a shortened RNA extraction protocol that will contribute to the reduction of the overall turn-around time of the TB-MBLA. This objective will support Ms. Kasinga Sharifah’s MSc in Molecular Biology at Makerere University. ,ii. Acquire knowledge about the adoptability, acceptability, feasibility, compatibility, satisfaction, and complexity of including TB-MBLA in routine TB care. This will be achieved through conducting end-of-study key informant interviews (KIIs), focus group discussions (FGDs), and surveys.,i. Understanding the baseline issues regarding the pathway to healthcare access, prior use of antibiotics and/or previous TB treatment, and socioeconomic status. This will be achieved by conducting a structured questionnaire study at different medical clinics around Kampala.,The overall objective of this study is to assess the feasibility, acceptability, and utility of the Tuberculosis-Molecular Bacterial Load Assay for monitoring TB treatment in three HIV clinics in Kampala and evaluate approaches that will reduce the turnaround time of the TB-MBLA assay.,
Uganda 2024-07-17 13:59:42 2027-07-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
NAMYENYA NAKITYO MARIAM
ID:
SELF-MANAGEMENT PRACTICES AND GLYCEMIC STATUS OF TYPE 2 DIABETES MELLITUS ADULT OUTPATIENTS ATTENDING THE DIABETES CLINIC AT KIRUDDU NATIONAL REFERRAL HOSPITAL
REFNo: HS4456ES

To determine the predictors of glycemic status among T2DM adult outpatients attending the diabetes clinic at KNRH.,To establish the relationship between self-management practices and glycemic status of T2DM adult outpatients attending the diabetes clinic at KNRH.,To evaluate the self-management practices of T2DM adult outpatients attending the diabetes clinic at KNRH.,To assess the glycemic status of T2DM adult outpatients attending the diabetes clinic at KNRH.,To investigate the self-management practices and the glycemic status of T2DM adult outpatients attending the diabetes clinic at KNRH.,
Uganda 2024-07-17 13:49:23 2027-07-17 Medical and Health Sciences Non-Clinical Trial Degree Award
Leo Okoya
ID: UNCST-2024-R004171
Socio-ecological and cultural factors in the use of pesticides in Smallholder Agri-food system in Koch Goma Sub- County, Northern Uganda
REFNo: SS2759ES

General Objective
- To examine the social, cultural and ecological factors in the use of pesticides in smallholder agrifood systems and its effects on humans and the environment
Specific objectives
1.To examine how tomato production positioned within smallholder agrifood production systems in Koch Goma Sub-County.
2.To assess the community perceptions of traditional pest and disease management practices vis a vis the current practices in tomato production in Koch Goma sub-county
3.To explore the discourses and knowledge circulating about the socio-ecological effects of pesticides in tomato production in Koch Goma Sub- County.
4.To examine the social lives of selected pesticides used in tomato production in Koch Goma Sub- County.

Uganda 2024-07-17 13:46:53 2027-07-17 Social Science and Humanities Non-Clinical Trial Degree Award
Moses Nasinyama Makoha
ID:
Approaches to Knowledge Translation and Management for Public Revenue Mobilization in Pallisa District, Uganda
REFNo: SS2709ES

Purpose of the study
To examine how approaches of Knowledge Translation support the management for Public Revenue Mobilization in Pallisa District, Uganda.

1.3.1 Objectives of the Study
The specific objectives of the study are to:
1. Assess the nature and methods (both local and modern) used for knowledge development to support the management for PRM in Pallisa.
2. Analyze the process and methods used in knowledge development to accelerate innovation in public revenue knowledge design in Pallisa.
3. Assess the institutional structures in place to support public revenue knowledge transfer in Pallisa.
4. Explore the role of key stakeholders in public revenue knowledge generation and management in Pallisa.


Uganda 2024-07-17 12:42:18 2027-07-17 Social Science and Humanities Non-Clinical Trial Degree Award
Julius Ssendiwala
ID:
Evaluation of the National PMTCT Group Antenatal Care/ Postnatal Care Differentiated Service Delivery model: Uganda 2021-2023
REFNo: SS2873ES

To estimate the cost of delivering the G-ANC/PNC DSD model of care as part of MCH service delivery for PBF AGYW and their infants by health facility level,To determine the acceptability, enablers and barriers of implementing the G-ANC/PNC model of care for PBF AGYW and their infants.,To determine the effectiveness of G-ANC/PNC DSD model of care on maternal and infant health outcomes across the continuum of care for mother-infant pairs, including retention rates.,To assess the uptake of G-ANC/PNC DSD model of care among PBF AGYWs,To measure the uptake, effectiveness and cost of the G-ANC/PNC DSD model of care for PBF AGYW and their infants for program improvement.,
Uganda 2024-07-17 12:07:59 2027-07-17 Social Science and Humanities Non-Clinical Trial Non-degree Award
Philip Rwezawula
ID: UNCST-2024-R003279
Probiotics and Bacteriophages as Biocontrol Agents of Motile Aeromonad Septicaemia in Nile Tilapia: A Holistic Approach to Disease Management in Aquaculture
REFNo: A451ES

To evaluate the synergistic effects of combining lytic phages with local probiotic Bacillus spp. on the growth performance and survival rates of Nile tilapia in the field under conditions of Aeromonas hydrophila exposure ,To evaluate the synergistic effects of combining lytic phages and local probiotic Bacillus spp. under lab conditions to prevent and/or cure MAS in Nile tilapia,To verify the potential of local lytic bacteriophages and probiotic Bacillus spp. to prevent or mitigate Motile Aeromonad Septicaemia (MAS) in farmed Nile tilapia under lab conditions,Isolation and characterization of local probiotic Bacillus spp. and local lytic bacteriophages,to assess the potential of bacteriophages and probiotics as biocontrol agents of Motile Aeromonad Septicaemia (MAS) in farmed Nile tilapia (Oreochromis niloticus). ,
Uganda 2024-07-17 12:06:50 2027-07-17 Agricultural Sciences Non-Clinical Trial Degree Award
Faith Nawagi
ID: UNCST-2021-R013751
AFREhealth-FAIMER Interprofessional Education Student Exchange Program Evaluation Plan.
REFNo: HS4461ES

The AFREhealth-FAIMER IPE program evaluation aims to assess the key process factors required for implementation of an IPE elective program, impact and the outcomes of the program at the student, faculty, institutional, and AFREhealth Network levels.,4. To document the key process factors of developing and implementing the AFREhealth-FAIMER IPE elective program. ,3. To identify the outcomes of the AFREhealth–FAIMER IPE elective program on the participating institutions and AFREhealth as an organization at large.,2. To evaluate the participating faculty, students, program managers, institutional leaders, and AFREhealth leaders’ perspectives on the AFREhealth-FAIMER IPE elective program curriculum. ,1. To establish the IPECP skills gained by the students participating in the AFREhealth-FAIMER IPE elective program. ,
Uganda 2024-07-17 12:04:18 2027-07-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Anxious   Niwaha Jackson.
ID: UNCST-2023-R008010
Patho-physiologic and metabolic characterisation of Lean Diabetes in Uganda (LEAN-D study)
REFNo: HS4533ES

1. To establish the principal cause of hyperglycemia in lean SSA diabetes. (Hyperglycemia is high blood sugar)
2. To determine the association between biomarkers of beta cell function, and body composition and lean type 2 diabetes.
3. To establish if Persistent Organic Pollutants are present in sufficient levels in individuals with lean SSA diabetes to contribute to the process of developing diabetes.
4. To translate knowledge products into formats that are accessible and usable by key stake holders to enhance lean diabetes diagnosis, and inform policy and intervention strategies.

Uganda 2024-07-15 8:24:33 2027-07-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Allan Kalungi
ID: UNCST-2022-R009843
Genetic, Biological and Psychosocial predictors of Incident and Persistent Internalizing Mental Disorders among Ugandan Children and Adolescents living with HIV: A Machine Learning Approach.
REFNo: HS4521ES

1. To build a machine learning model for prediction of prevalent, incident, and persistent cases of Internalizing Mental Disorders among Ugandan children and adolescents living with HIV.
2. To evaluate the performance of the machine learning model (developed in 1 above) based on each of genetic, biological, and psychosocial factors respectively.
3. To evaluate the performance of the machine learning model based on the combination all the three factor domains of genetic, biological, and psychosocial factors.

Uganda 2024-07-15 8:22:11 2027-07-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sheila Balinda Nina
ID: UNCST-2021-R013804
Advancing Vaccine Development: Harnessing Multiple Antigenic Epitopes for Crimean-Congo Hemorrhagic Fever in Humans and Animals
REFNo: HS4493ES

Overall objective To develop and evaluate an adenovector CCHFV vaccine candidate. Sub-study general objectives i) To design the CCHFV immunogens and construct an adenovector CCHF vaccine candidate by conjugating the immunogens into the adenovector backbone. ii) To conduct preclinical studies of the CCHF vaccine in mice and non-human primates (animal models). iii) To translate knowledge products into formats that are accessible and usable by key stakeholders to enhance CCHF vaccine discovery and scale up.
Uganda 2024-07-15 8:16:36 2027-07-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jolly  Kamugisha G.K.
ID: UNCST-2023-R005715
Evaluation of The Early Childhood Nutrition Programme In The Karamoja Region, Uganda. RefNo: JCRC-2024-78:
REFNo: HS4490ES

To assess ECD centre readiness to implement integrated early childhood nutrition interventions in order to inform programming that fosters early childhood development in the Karamoja regionTo determine the early childhood developmental status of children aged 0-24 months in the Karamoja region. To determine the contextual barriers and facilitators to implementation of comprehensive nutrition interventions in ECD centres and their catchment communities in the Karamoja region To determine the effect of comprehensive early childhood nutrition interventions on Early Childhood Developmental status among children aged 24-59 months in the Karamoja region
Uganda 2024-07-12 14:50:24 2027-07-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mamerito Nturanabo
ID: UNCST-2024-R004377
Social Equity Interventions and Maternal health outcomes in Bugiri District, Eastern Uganda
REFNo: SS2781ES

To establish the effect of legislation on the maternal Health in Bugiri District, Eastern Uganda,To establish the civic education effect on maternal health in Bugiri District, Eastern Uganda.,To establish Health provision effect on maternal health in Bugiri District, Eastern Uganda,To assess the relationship between social equity interventions and maternal health outcomes in Bugiri District, Eastern Uganda.,
Uganda 2024-07-10 13:41:35 2027-07-10 Social Science and Humanities Non-Clinical Trial Degree Award
Shamirah Najjinda
ID:
Family support, entrepreneurial resources, resilience and entrepreneurial wellbeing of women entrepreneurs in the hospitality and tourism industry of Uganda
REFNo: SS2842ES

To determine the levels of understanding of entrepreneurial wellbeing by women entrepreneurs in Uganda.To establish the relationship between family support and entrepreneurial wellbeing of women entrepreneurs in the hospitality and tourism industry of Uganda.To examine the relationship between entrepreneurial resources and entrepreneurial wellbeing of women entrepreneurs in the hospitality and tourism industry of Uganda.To explore the influence of entrepreneurial resilience on the entrepreneurial wellbeing of women entrepreneurs in the hospitality and tourism industry of Uganda.
Uganda 2024-07-10 13:40:22 2027-07-10 Social Science and Humanities Non-Clinical Trial Degree Award
Lucas Ampaire
ID:
DIGITIZED CBC RESULTS TRANSMISSION TO SHORTEN TURN AROUND TIME AT MBARARA REGIONAL REFERRAL HOSPITAL (dCRT STUDY)
REFNo: HS4264ES

To design a mobile app as an intervention to shorten delay for CBC results transmission from the Mbarara Regional referral hospital Laboratory to the requesting clinician,To determine the perceived contributing factors to CBC results delay at Mbarara regional referral Hospital,To establish the prevalence of CBC results delays at Mbarara regional referral Hospital:,
Uganda 2024-07-10 13:38:14 2027-07-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Patricia Nabwami Esther
ID:
Evaluating the Health Systems Preparedness for Ebola Virus Disease outbreak in Mubende and Kassanda Districts in Uganda
REFNo: SS2828ES

3. To establish the existing capacities for management of EVD outbreaks containment at the local health facilities. ,To determine the status of stock piling levels for Ebola Virus Disease in health facilities.,1. To establish the level of preparedness among health care workers’ for containment of Ebola Virus Disease.,To evaluate the preparedness levels of health system for Ebola outbreak response in Mubende and Kassanda Districts in Uganda. ,
Uganda 2024-07-10 13:37:12 2027-07-10 Social Science and Humanities Non-Clinical Trial Degree Award
Ellen Forsman Larsson
ID:
“Have you been saved?” Ecstatic exorcism as therapeutic healing
REFNo: SS2494ES

This project focuses on the Balokole church, aiming to produce an ethnographic analysis of the movement. The purpose of this research is to understand how the movement interacts with global Christianity while simultaneously inflecting local practices. In particular, It will look at the types of worship undertaken in the church, and how they are experienced within the congregation. The members of this movement commonly experience so-called ‘deliverances’ - where congregants are exorcised and cleansed of demons and evil spirits. Those who undergo deliverances tell of its healing effects. The ultimate aim of the project is to understand what deliverance is, and what happens to a person when they undergo it. It will also explore the personal transformation that happens when a person is ‘born again’, to better understand the therapeutic effects which conversion, deliverance and other rituals can have.
Sweden 2024-07-10 13:35:12 2027-07-10 Social Science and Humanities Non-Clinical Trial Degree Award
Jonathan Kitonsa
ID:
Assessing the knowledge, perceptions, and uptake of HPV vaccine and evaluation of vaccine delivery strategies among non-school-going girls in southwestern Uganda
REFNo: HS4559ES

Quantitative study objectives 1. To assess knowledge, attitudes, and perceptions about the HPV vaccine among non-school going girls between 9 and 20 years. 2. To determine HPV uptake, willingness, and barriers to use HPV vaccines among nonschool going girls between 9 and 20 years. 3. To determine favourable vaccine delivery strategies for non-school going girls. Qualitative study objectives 1. To explore the willingness and acceptability of taking up an HPV vaccine among nonschool going girls between 9 and 20 years. 2. To explore the knowledge, attitudes, and perceptions about HPV vaccine among nonschool going girls, parents/care givers, and healthcare providers. 3. To describe the facilitators and barriers to the uptake of HPV vaccine among non-school going girls, parents/care givers, and healthcare providers.
Uganda 2024-07-10 13:31:20 2027-07-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Solomon Nsumba
ID:
Intelligent wearable systems for detecting medication errors at CoRSU Rehabilitation Hospital
REFNo: SIR360ES

To design and implement a low-power, real-time wearable system that seamlessly integrates with existing medical equipment, facilitating continuous monitoring and detection of medication errors during surgical procedures.,To prototype a software system capable of providing real-time feedback to medical personnel and generating automated records based on detected medication errors, integrating insights from the developed computer vision models.,To develop advanced computer vision models tailored to accurately detect and classify drug delivery events and associated errors, leveraging insights from the curated dataset,To curate a comprehensive video/image dataset capturing diverse medical drug events and errors in real-time during surgical procedures.,Overall Goal is to develop machine learning models that can detect medical drug events and errors in real-time during surgery.,
Uganda 2024-07-10 13:29:17 2027-07-10 Engineering and Technology Non-Clinical Trial Degree Award
Kristen Little Marie
ID:
Exploring the Non-Hormonal and On-Demand Contraceptives Value Propositions: Perspectives from End Users, Private Sector Healthcare Providers, and Stakeholders in Kenya, Nigeria, and Uganda
REFNo: SS2745ES

: To understand the benefits, challenges, and preferences for the on-demand pill, including product naming and framing, and perspectives on a standalone vs. EC+ on-demand pill, among potential end-users. Sub-aims: 1.) To explore women’s perceptions regarding non-hormonal contraceptives (relative to hormonal options) and their stated preferences for product attributes including dosing schedule, side effects, and benefits; 2.) to describe women’s current use of emergency contraceptive pills, including routine, regular, or repeated use of ECPs, and these users’ perspectives on a potential on-demand pill product.,To understand motivators and barriers and support required for private healthcare providers (HCPs) to consider stocking/selling the LNG 1.5 on-demand/pericoital contraceptive pill. Sub-aim: To understand provider perspectives on the value of and barriers to a weekly, non-hormonal pill in the private sector.,Explore the acceptability of on-demand and non-hormonal contraceptives among private providers, user preferences for on-demand and weekly non-hormonal products among adult women, and key informants and market actors to inform clinical trial pathway decisions and product positioning,
USA 2024-07-10 13:28:15 2027-07-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
David Mathuva
ID:
Transforming Social Ministries into Sustainable Social Enterprises by the Religious Sisters in the Catholic Church
REFNo: SS2158ES

The purpose of this study is to contribute to the body of knowledge on the work of Catholic sisters as they seek to transform their social ministries and charities into sustainable social enterprises.
Kenya 2024-07-10 13:25:42 2027-07-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Robert Downing George
ID: UNCST-2020-R014615
Clinical Equivalence Validation of the ANC panel (professional use)
REFNo: HS4369ES

The primary objectives of this study are:
• To evaluate the equivalence of the ANC panel test results based on a finger-stick sample against the individual DetermineTM tests based on a) finger-stick samples and b) venous whole blood samples.
The secondary objectives of this study are:
• To evaluate the equivalence of the ANC panel test results based on a finger-stick sample against laboratory-based reference testing.
As a secondary objective, a user experience questionnaire will also be completed by each professional test user
UK 2024-07-10 13:24:19 2027-07-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mark Marvin Kadigo
ID: UNCST-2024-R004323
Perspectives and preferences of both refugees and hosts on refugee local integration in Uganda
REFNo: SS2797ES

The main objective of the study is to comprehensively evaluate the perspectives and preferences of both refugee and host populations regarding the local integration of refugees within Uganda.To determine the average preference of both refugees and hosts (Ugandans) for the different integration scenarios
Uganda 2024-07-09 18:43:00 2027-07-09 Social Science and Humanities Non-Clinical Trial Degree Award
Harold OGWAL
ID: UNCST-2024-R005378
EFFECTS OF WETLAND SPATIO-TEMPORAL CHANGES ON WATER QUALITY AND SEDIMENTS, A CASE OF OKOLE WETLAND IN LIRA CITY.
REFNo: NS815ES

To explore the socio-ecological and economic drivers associated with wetland degradation within Lira City ,To examine the effect of wetland changes on the sediment concentration of the wetland systems within Lira City ,To evaluate the impacts of wetland degradation on the water quality of the identified wetland systems within Lira City,To conduct spatio-temporal analysis of wetland changes between 1999 and 2023 within Lira City,To study the effects of Okole wetland spatiotemporal changes on water quality and sediments within Lira city,
Uganda 2024-07-09 18:37:28 2027-07-09 Natural Sciences Non-Clinical Trial Degree Award
Nsobya  Samuel
ID: UNCST-2021-R012265
Ex vivo characterization of the drug susceptibility of malaria parasites in Uganda (Ex vivo study)
REFNo: HS4481ES

Primary objective
1. To characterize the ex vivo drug susceptibility of P. falciparum isolates collected from multiple sites in Uganda.
Secondary objectives
1. To characterize mutations that mediate drug resistance in P. falciparum isolates collected from multiple sites in Uganda
2. To characterize mutations that mediate drug resistance in banked P. falciparum previously collected from multiple sites in Uganda.
3. To culture, adapt and store P. falciparum isolates to enable studies of mechanisms of antimalarial drug resistance.
4. To measure drug levels in serum or plasma to help to understand treatment responses.

Uganda 2024-07-09 18:35:24 2027-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Diana Namumbejja Abwoye
ID:
Preventive medicine for displaced persons/refugees residing in Palabek settlement
REFNo: SS2818ES

To understand the experiences of refugees in Palabek resettlement with preventive healthcare through in-depth interviews,To explore knowledge, beliefs and attitudes of preventive healthcare among refugees living in Palabek resettlement through in-depth interviews, The long-term goal is to obtain a deeper understanding of how refugees living in Palabek resettlement camp perceive and utilize preventing medicine and inform stakeholders in the camp of any gaps or needs that may improve access and care. It is imperative to understand refugees’ perceptions and experiences with preventive medicine and establish which aspects of their refugee experience may influence utilization of preventive healthcare when available.,
USA 2024-07-09 18:33:18 2027-07-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
Bjorn Van Campenhout -
ID: UNCST-2020-R014080
The impact of the World Food Program (WFP) indirect conditional contracts
REFNo: SS2800ES

The research seeks to assess the impact of WFP's indirect conditional contracts on (maize) value chain outcomes such as access to reliable markets, value chain transformation and upgrading, welfare of the participating actors, and the scalability of the policy.
Belgium 2024-07-09 18:28:29 2027-07-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
Maxson Anyolitho Kenneth
ID: UNCST-2021-R013447
Assessing community drug distributors’ participation in the river blindness program currently undergoing mass treatment: A case study of Kasese, Kitgum and Adjumani districts in Uganda
REFNo: SS2838ES

propose recommendations for improving/enhancing CDDs’ involvement and participation in RB programs for its future sustainability.,To assess communities’ perspectives about using CDDs during MDA. ,To establish whether the CDDs are needed to implement the MDA program and identify key stakeholders involved in the program at the community level.,To examine the facilitators and barriers to CDDS’ involvement and participation in the program. ,To explore the experiences and perspectives of the CDDs regarding their participation in the RB MDA program,To Identify the proportion of CDDs that have been selected and trained and those that have participated in the RB MDA program. ,The main objective of this study is to assess CDDs’ participation in the RB program activities in three selected districts currently undergoing mass treatment in western and northern Uganda to guide the review of existing programs or develop new ones altogether, to improve the CDDs’ future involvement and participation in MDA programs,
Uganda 2024-07-09 18:26:45 2027-07-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
Eugene Ruzagira
ID: UNCST-2023-R008282
Implementing oral (event-driven and daily) and long-acting Pre-exposure prophylaxis (PrEP) in mobile men in Sub-Saharan Africa: a phase 3b, open-label, hybrid type 2 implementation and effectiveness trial (MOBILE MEN)
REFNo: HS4366ES

Overall Objective
To assess effectiveness and implementation of long-acting cabotegravir (CAB-LA) and oral Truvada (both daily and event driven) through comparison of uptake, retention in care, coital coverage, and participant choice.
Uganda 2024-07-02 15:08:06 2027-07-02 Medical and Health Sciences Clinical Trial Non-degree Award
Kiconco Prisca
ID: UNCST-2023-R005626
HUMAN RESOURCE MANAGEMENT IN RELIGIOUS INSTITUTES IN UGANDA
REFNo: SS2769ES

To create awareness among the religious, basing on the fact that religious institutes have qualified, skilled and capable members who when distributed rightfully to different fields, there is possible production of effective results. ,To provide help to other religious institutes and other consecrated persons in and beyond Uganda as a resourceful material they can rely on as they manage human resource of the institute (s).,To establish the degree at which religious Institutes in Uganda are effectively managing their human resources for the benefits of the Institute and that of the Universal Church.,
Uganda 2024-07-02 13:42:13 2027-07-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Faustino Byanyima
ID: UNCST-2024-R004003
Establishing the Effect of Financial Literacy on Financial Products Utilisation: a Case Study for Youth and Women Small Medium Enterprises in Southwestern Uganda.
REFNo: SS2660ES

Main Objective
The main objective of the study is to examine the effect of financial literacy on financial products utilisation among youth and women SMEs in Southwestern Uganda.

Specific Objectives
1. To determine the level of financial literacy among youth and women SMEs in Southwestern Uganda.
2. To identify the financial products used by youth and women SMEs in Southwestern Uganda.
3. To investigate the challenges and opportunities of financial product utilisation among youth and women SMEs in Southwestern Uganda.

Uganda 2024-07-02 13:40:38 2027-07-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Racheal Nalunkuma
ID: UNCST-2020-R014616
Effect of the Facility-Based-Group-Model of the Differentiated Service Delivery on Stigma and Antiretroviral-Therapy-Adherence among Adolescents Living with Human-immunodeficiency-Virus in Central Uganda.
REFNo: HS4373ES

1. To evaluate the effect of the FBG model on ART Adherence among ALHIV in Central Uganda, comparing urban and rural HIV clinics from 2016 to 2023.
2. To determine the level of stigma among ALHIV under the FBG Model in Urban versus Rural HIV Clinics in Central Uganda.
3. To explore lived experiences towards the FBG Model in reducing HIV-associated Stigma and enhancing ART adherence among ALHIV in Urban and Rural HIV Clinics in Central Uganda.
4. To explore Peer leaders and Healthcare workers’ perception towards the FBG Model in reducing HIV-associated Stigma and enhancing ART adherence among ALHIV in Urban and Rural HIV Clinics in Central Uganda.

Uganda 2024-07-02 13:39:27 2027-07-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Donald Kugonza Rugira
ID: UNCST-2021-R013291
From Project to Program-based Extension Service Delivery: Assessment of the Impact of Interventions Implemented by the Centre for Sustainable Rural Livelihoods Program in Kamuli, Uganda
REFNo: A434ES

• Analyze the model/s and approaches used when delivering agricultural extension programs in Kamuli. • Identify farmers' perceptions of the effectiveness of the various agricultural technologies? used under the ISU-UP. • Identify clients' descriptions of effective and impactful agricultural and agricultural extension programs. • Capture and document clients’ success stories as a result of participating in the ISU-UP. • Capture donors' and program managers' perceptions of the agricultural and agricultural extension programs.
Uganda 2024-07-02 13:38:11 2027-07-02 Agricultural Sciences Non-Clinical Trial Non-degree Award
Bernard Omech
ID: UNCST-2020-R014820
Baseline characteristics and development of an integrated chronic disease care model for diabetes and hypertension management at primary healthcare facilities (ICDC)
REFNo: HS4285ES

To co-design an integrated chronic Diseases care model for management of hypertension and Diabetes mellitus through a participatory process to inform future intervention studies in Lango sub-region ,To examine the knowledge and practice of health care providers towards integration of chronic care for Hypertension and diabetes at selected PHC facilities in Lango sub-region ,To assess the patient’s perception of integration of chronic care for hypertension and diabetes mellitus among patients among patients attending selected primary health care facilities in Lango sub-region ,To determine baseline profiles (HBA1C levels, BP levels, QoL) of patients with hypertension and diabetes mellitus attending outpatient clinic at selected Primary health facilities in Lira City and District ,To evaluate baseline characteristics and develop a model of integrated chronic Disease care for management of hypertension and diabetes at primary health care in Lango Sub-region, Northern Uganda,
Uganda 2024-07-02 12:56:36 2027-07-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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