Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Lauben Kyomukama Amagara
ID:
MROP-Mesh versus Desarda technique for short-term surgical outcomes in open inguinal hernia repair at Kampala International University Teaching-Hospital: A randomized controlled trial
REFNo: HS1073ES

Purpose of the study/General objective: To compare the MROP-mesh and Desarda techniques for short-term surgical outcomes in open inguinal hernia-repair among patients at Kampala International University Teaching Hospital
Specific objectives
i. To assess the perioperative factors following open inguinal hernia repair with MROP mesh versus Desarda technique at Kampala International University Teaching hospital
ii. To compare the mean operative time used for open inguinal hernia repair with MROP mesh versus Desarda technique at Kampala International University Teaching Hospital.
iii. To evaluate the occurrence rates of pain following open inguinal hernia repair with MROP mesh versus Desarda technique at Kampala International University Teaching hospital.

 Uganda 2021-07-05 2024-07-05 Medical and Health Sciences Degree Award
Mary Kulabako Kulabako
ID:
Teachers burnout and students wellbeing in government aided public secondary schools in Uganda
REFNo: SS707ES

i. Examine examples and levels of burnout among secondary school teachers in selected public/government aided schools in Uganda.
ii. Explore how teacher burnout affect students’ wellbeing

 Uganda 2021-07-05 2024-07-05 Social Science and Humanities Degree Award
PETER NABENDE
ID:
Improving Point-of-Care Learning for Prostate Cancer Imaging using Machine Learning
REFNo: SIR59ES

1. To develop a competence-based educational curriculum and content for teaching prostate cancer imaging tailored to the PoC.
2. To develop an ML-driven gamified interactive PoC education model for prostate cancer imaging.

 Uganda 2021-07-05 2024-07-05 Engineering and Technology Non-degree Award
Adam Branch
ID:
Rethinking Vulnerability to COVID-19 Lockdowns in Gulu, Uganda
REFNo: SS786ES

Research questions
(1) Our first research question is: what are the mechanisms by which lockdowns are causing social and economic harm, in particular the hidden harms inflicted upon the most vulnerable?
(2) Our second research question is: How are people adapting to or innovating beyond lockdowns to secure livelihoods and ensure viable futures for themselves and others?
(3) How can lockdowns, and mitigation policies, be designed to minimize harm and support innovative strategies among those most vulnerable to lockdowns’ impacts?

Specific Objectives

(1) To describe the mechanisms by which lockdowns are causing social and economic harm, the hidden harms inflicted upon the most vulnerable people in urban and peri-urban areas of Gulu

(2) To explore people’s adaption to or innovation beyond lockdowns to secure livelihoods and ensure viable futures for themselves and others

(3) To explain how lockdowns and mitigation policies can be designed to minimize harm and support innovative strategies among those most vulnerable to lockdowns’ impacts

 USA 2021-07-05 2024-07-05 Social Science and Humanities Non-degree Award
Julian Natukunda
ID:
Long-term retention and associated positive practices among Community Client Led ART Distribution groups (CCLADs) in Uganda
REFNo: SS895ES

3. To investigate the association between uncommon practices and long-term retention in CCLADs to confirm uncommon practices are PD behaviors,2. To identify uncommon practices (group and individual) among high retention groups, using the positive deviance approach,1. To assess retention and time for time to withdrawal from CCLAD groups since enrolment in the program ,
 Uganda 2021-07-05 2024-07-05 Social Science and Humanities Non-Clinical Trial Degree Award
Elodie Freymann Marion
ID:
Intergenerational Transmission of Self-Medicative Knowledge in Chimpanzees? Examining Putative Modes and Mechanisms of Information Transmission Between Chimpanzees
REFNo: NS257ES

Homo sapiens are not the only species to self-medicate. Over the last few decades, self-medication has been observed in a variety of primate and non-primate species and throughout a wide range of localities (Janzen, 1978; Huffman, 2016). Non-human self-medication takes many forms and involves a variety of medicinal resources. These include self-medicative resources (SMRs) known to be used in medicinal behaviors like leaf swallowing (Wrangham & Nishida, 1983) and bitter-pith chewing (Huffman & Seifu, 1989), putative therapeutic resources (PTRs) which are irregular dietary items with known bioactive properties, ingested when an individual is ill, and medicinal foods (MFs) which are foods eaten at low frequencies in the absence of symptoms, at certain times of year when their associated medicinal properties are likely most beneficial for preventing future infection or illness (Huffman, 1997). While bioactive and limitedly nutritious botanical species remain the best studied medicinal resources, clay, termite soil, and cambium beneath peeled tree bark are also widely acknowledged as possessing medicinal properties (Pebsworth et al., 2019). In recent literature, many other resource types have been proposed as candidates for further study, including driver ants, honey, ash, and mushrooms, although no studies thus far have empirically established the intentional use of these resources by sick chimpanzees.

Although chimpanzees have been shown to transmit medicinal information to their peers in experimental settings (Huffman & Hirata, 2004; Huffman et al., 2010), the modes, mechanisms, and social learning processes through which chimpanzees transmit medicinal knowledge and behaviors remain untested in free-ranging chimpanzees. This project, titled ‘Intergenerational Transmission of Self-Medicative Knowledge in Chimpanzees? Examining Putative Modes and Mechanisms of Information Transmission Between Chimpanzees’ will consist of three studies, all of which aim to test hypotheses related to intergenerational self-medicative knowledge transmission: the modes and mechanisms facilitating this transmission, and how this knowledge disperses across communities in wild populations. This research will be carried out as part of the completion of Ms Freymann’s DPhil at the University of Oxford.

The first study, titled ‘Gestural Communication During Chimpanzee Self-Medication Events? An analysis of multi-modal signaling between self-medicating models and observers’ will examine whether or not model individuals use specific multi-modal signals and/or increased signaling frequencies to communicate medicinal information to offspring or non-kin observers. The second study, titled ‘Mapping the Self-Medicative Landscape: Do wild chimpanzees revisit medicinal resource sites when seeking treatment?’ will evaluate the presence or absence of habitually utilized SMR sites, to determine whether or not preferred locational ‘hotspots’ exist for chimpanzees within their habitat, and may function as contextual clues to alert chimpanzee observers to the potential onset of a self-medicative event. The third study, titled ‘Evaluating Inter-Community and Intra-Community Variation in Resource Selection and Self-Medicative Behaviors' will evaluate whether or not medicating individuals demonstrate inter-group and/or intra-group variation in their employment of self-medicative behaviors and medicinal resource selection, as well as whether or not social and demographic variables can predict the presence of these variants.

There are two neighboring habituated chimpanzee communities in Budongo forest, the Sonso community, with has ~65 individuals, and the more recently habituated Waibira community which has ~120 individuals. While this research will begin with the Sonso community, if this group becomes unavailable for study due to other scheduled projects, Ms Freymann will flexibly move her data collection to the Waibira community to make the study a cross-community comparison.

Research Questions
1. Gestural Communication During Chimpanzee Self-Medication Events?
• Are gestural signals used at higher frequencies during medicinal events than during normal feeding events?
• Do models use signals at higher frequencies in the presence of an observer during medicinal ingestion events than during medicinal events in which the medicating individual is alone?
• Do medicators increase signaling frequencies during medicinal events based on relatedness to observers?
• Is the proportion of ‘successful’ begging outcomes higher during medicinal events than the proportion of ‘successful’ begging outcomes during normal feeding events?
• Do signaling frequencies between individuals during medicinal events vary based on demographic characteristics or health state?
• Are there specific signals that are used during medicinal events which are not commonly used during normal feeding events?
• Do signal types between models and observers exhibited during medicinal events vary based on social relationships, demographic characteristics, resource type, or behavioral type?

2. Mapping the Self-Medicative Landscape
• Are locations where SMR or PTR ingestion events took place spatially clustered into hot spots?
• Do individuals re-use the same SMR resource hotspots when they are sick?
• Do sick individuals utilize sites with high resource abundance scores over sites where the resource is scarce?
• Do any demographic variables (age, sex and reproductive status) predict which individuals visit which medicinal hotspots?
• When sick individuals travel away from the group to self-medicate, do they choose the most efficient route, foregoing nutritious resources and normal feeding sites to get to the closest available resource, or do they ignore closer sites and return to habitually used sites?

2. Evaluating Inter-Community and Intra-Community Variation in Resource Selection and Self-Medicative Behaviors
• Across all individuals in the community, are specific sickness behaviors correlated with an increase in ingestion of any specific resource type or species?
• Does there appear to be behavioral variation during medicinal events?
• If variation does exist, can horizontal or vertical transmission predict the diffusion pathways of the behavioral variants?
• Does variation in self-medicative behavioral techniques or resource selection appear to be cultural?

 USA 2021-07-05 2024-07-05 Natural Sciences Non-Clinical Trial Degree Award
Mary Grace  Nakate Nakate
ID:
The psychological experience and the Perceived Support of Nurses who Underwent Mandatory Quarantine or Self Isolation During Covid-19 Pandemic in Uganda and Kenya
REFNo: SS877ES

Major Objective
To explore the psychological experience and perceived support of nurses who underwent mandatory quarantine or self-isolation in Uganda and Kenya during the COVID-19 pandemic.

Specific Objectives
1.Describe the experiences of depression among the nurses who underwent mandatory quarantine or self-isolation in Uganda and Kenya during the COVID-19 pandemic.
2.Examine the anxiety experienced by the nurses who underwent mandatory quarantine or self-isolation in Uganda and Kenya during the COVID-19 pandemic.
3.Describe the stressful experiences of nurses who underwent mandatory quarantine or self-isolation in Uganda and Kenya during the COVID-19 pandemic.
4.Describe the perceived psychological support of the nurses who underwent mandatory quarantine or self – isolation during the COVID-19 pandemic. in Uganda and Kenya

 Uganda 2021-07-05 2024-07-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
ASIIMIRE  DONATH
ID: UNCST-2021-R013270
 Women's Economic Empowerment and Changing Family Patterns in Ankole Sub-region
REFNo: SS873ES

Women's eduction and changing family patterns in A nkole.
Earning of Income by women and changing family patterns in Ankole Sub-region.
Women's access and control over productive assets and changing family patterns in Ankole
 Uganda 2021-07-05 2024-07-05 Social Science and Humanities Non-Clinical Trial Degree Award
marie nanyanzi
ID: UNCST-2019-R001553
 Sauti Za Wananchi (Voices of citizens) Baseline Survey Panel II
REFNo: SS887ES

o Gather opinions from the citizens on the key services they receive especially
 Establish citizen access to safe water;
 Establish citizen access and usage of health services;
 Establish the citizens attitudes and practices on issues related to COVID-19
 Find out level of participation/involvement/interaction in development and public activities /institutions;
 Find out access and usage of financial services amongst citizens;
 Find out how; what and when citizen access different type of information including government and development information.
 Establish the knowledge, Attitudes and Practices (KAPs) of citizens on different policies; laws and regulations etc

 Uganda 2021-07-05 2024-07-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Amos Kijjambu
ID:
EVALUATION OF THE BARRIERS, OPPORTUNITIES, AND VACCINE HESITANCY FOR CHILDHOOD IMMUNISATIONS IN URBAN AREAS; A CASE STUDY OF NANSANA MUNICIPALITY, UGANDA.
REFNo: HS1507ES

General Objective
• To assess the barriers, opportunities, and vaccines hesitancy for childhood immunizations in urban areas to design relevant interventions to improve immunization coverage and improve the health outcomes of children.
Specific Objectives
• To establish the immunization coverage rates in Nansana municipality for children aged under two years.

• To identify factors (parents/guardians-child, health system factors) associated with uptake of immunization for preventable childhood illnesses in Nansana Municipality, Uganda.

• To establish the prevalence of vaccine hesitancy among parents/guardians of children aged <24 months in Nansana Municipality.
• To identify the determinants of vaccine hesitancy among the parents/guardians of children aged < 24 months in Nansana Municipality.

Uganda 2021-07-05 2024-07-05 Medical and Health Sciences Non-Clinical Trial Degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
 Exploring Understanding and Acceptability for Participation in Randomized Placebo-Controlled Trials and Delayed Consent Involving Sepsis Patients in Uganda (REVISTA-QUAL)
REFNo: SS913ES

General objective
The overarching goal of this study is to explore patients’, clinical providers’ and caregivers’ understanding of placebo controls, delayed consent and overall acceptability of participation in RCTs involving sepsis patients in a representative Ugandan RRH.
4.3 Specific objectives
1. To describe the patients’, clinical providers’ and caregivers’ understanding of RCTs and the informed consent processes in a representative Ugandan RRH
2. To explore the patients’, clinical providers’ and caregivers’ acceptability of participation in RCTs, including being randomized to a placebo arm and alternative approaches to the consenting process (e.g., delayed consent) for critically ill patients hospitalized in a representative Ugandan RRH.

 Uganda 2021-07-05 2024-07-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Francis Anyanzu
ID:
The role of social networks in destination selection among urban refugees in Uganda
REFNo: SS519ES

Main objective
To investigate the role of social networks in destination selection among the urban refugees in Uganda
Specific objectives
a) To investigate the socio-demographic characteristics of the urban refugees in Uganda
b) To map the movement histories and social networks of the urban refugees in Uganda.
c) To examine the influences of social networks in the selection of city of destination.

 Uganda 2021-07-02 2024-07-02 Social Science and Humanities Degree Award
Laban Musinguzi Kashaija
ID: UNCST-2020-R014407
 Knowledge, Attitudes and Practices (KAP) Study on Children with Disabilities (CWD) living in families and institutions in Uganda
REFNo: SS585ES

The study seeks to achieve two primary aims/objectives:
1. To evaluate the current Knowledge, Attitudes and Practices (KAP) regarding the (i) attributes and conceptualization of CWD (ii) the use of institutional care for CWD and (iii) the barriers/enablers of the full and meaningful integration of CWD into community life.
2. To explore possible interplay between the identified Knowledge/Attitudes and Practices. This includes investigating the relations between the conceptualization/attributes of CWD, the use of institutional care for CWD and the integration of CWD into community life.
Uganda 2021-07-02 2024-07-02 Social Science and Humanities Non-degree Award
MICHAEL KAWOOYA GRACE
ID: UNCST-2020-R014672
 A Retrospective review of new interventional and selected imaging procedures at ECUREI-Mengo Hospital from 2008-2018
REFNo: HS1053ES

Main Objective
1. To identify diagnostic and interventional radiology procedures at ECUREI radiology department, Mengo Hospital.

Specific Objectives
1. To identify and determine image-guided interventional radiology procedures and related outcomes at ECUREI radiology department, Mengo Hospital from 2008 to 2018
2. To identify and determine diagnostic radiology procedures and related outcomes at ECUREI radiology department, Mengo Hospital from 2008 to 2018.
 Uganda 2021-07-02 2024-07-02 Medical and Health Sciences Non-degree Award
Pia Raffler Johanna
ID:
Access to social media during COVID-19: An analysis of social media's effect on engagement with public affairs and health behaviours in Uganda
REFNo: SS682ES

This study’s objectives are twofold. First, we seek to generate descriptive evidence relating to an important and understudied topic, as outlined in Section 2: social media usage in the Global South, in particular in Uganda. This aspect of our research will generate informative data on the frequency of social media use among peri-urban Ugandans under the age of 40, the types of social media they use, and whether they use it for entertainment, to seek information, or to communicate with fellow citizens and local politicians.
Second, we seek to generate causal evidence regarding the effect of increased access to social media on knowledge and behavior with regards to COVID-19 and public affairs, as well as general measures of wellbeing. With regard to knowledge, this causal component of the study will assess whether greater access to social media can help to inform citizens about public affairs and COVID-19, and the extent to which social media contributes to the spread of misinformation. With regard to behavior, the study will assess whether increased access to social media leads to disengagement from real-life social interactions, increased community and political engagement, and changes in the adoption of safe practices to prevent the spread of COVID-19. With regard to wellbeing, the study will assess whether greater access to social media leads to decreased happiness and wellbeing, as has been found in other contexts such as the United States.
Germany 2021-07-02 2024-07-02 Social Science and Humanities Non-degree Award
Josephine  Ataro
ID:
MANAGEMENT OF INDIGENOUS MATERNAL HEALTH KNOWLEDGE: A CASE OF ACHOLI SUB-REGION, NORTHERN UGANDA
REFNo: SS719ES

i) To examine the existing indigenous maternal health knowledge practices in Acholi Sub-region, Northern Uganda.
ii) To examine the current methods for managing indigenous maternal health knowledge in Acholi Sub-region, Northern Uganda.
iii) To examine the regulatory and policy framework on indigenous maternal health knowledge in Acholi Sub-region, Northern Uganda.
iv) To identify the factors influencing the management of indigenous maternal health knowledge in Acholi Sub-region, Northern Uganda.

Uganda 2021-07-02 2024-07-02 Social Science and Humanities Non-Clinical Trial Degree Award
Brenda Ainomugisha
ID: UNCST-2021-R013462
 CERVICAL AMNIOTIC FLUID BACTERIOLOGY AND FACTORS ASSOCIATED WITH ANTIBIOTIC RESISTANCE IN PREMATURE RUPTURE OF MEMBRANES AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS1459ES

General objective

To determine the bacteriology in cervical amniotic fluid, the antibiotic susceptibility and factors associated with antibiotic resistance among women with premature rupture of membranes at Mbarara Regional Referral Hospital.

Specific objectives

1. To determine the prevalence of bacterial growth in cervical amniotic fluid of women with premature rupture of membranes at Mbarara Regional Referral Hospital.
2. To describe the cultured bacteria and antibiotic susceptibility patterns in cervical amniotic fluid of women with premature rupture of membranes at Mbarara Regional Referral Hospital.
3. To identify bacteria using 16s PCR and sequencing method in culture negative cervical amniotic fluid of women with premature rupture of membranes at Mbarara Regional Referral Hospital.
4. To determine the factors associated with antibiotic resistance among women with premature rupture of membranes at Mbarara Regional Referral Hospital.

 Uganda 2021-07-02 2024-07-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Dirk Verschuren H
ID:
Half-precessional solar insolation and the long-term climate history of equatorial East Africa
REFNo: NS121ES

The main objective of this project is to constrain the area of East Africa which has experienced a truly low-latitude climate history influenced primarily by long-term trends in local solar insolation, rather than by the influence of changes in the extent of Northern Hemisphere glaciation. Our working hypothesis is that this area is limited to the region where rainfall originates predominantly from the Indian Ocean rather than the tropical Atlantic Ocean.
 Belgium 2021-07-01 2024-07-01 Natural Sciences Non-degree Award
Emily Tumwakire
ID:
Sexual and reproductive health of people with mental illness: Ugandan mental health care worker’s perspectives and experiences.
REFNo: SS911ES

1. To explore Ugandan mental health care worker’s perspectives and experiences on the sexual and reproductive health of people living with mental illness in Uganda. ________________________________________ Specific Objectives 1. To understand the sexual and reproductive health challenges of people with MI in Uganda from the perspectives of mental health care workers. 2. To identify the current SRH service provisions in the mental health unit from the perspectives of mental health care workers. 3. To explore experiences of Mental Health Care workers in provision of SRH to people with MI in mental health unit.
Uganda 2021-07-01 2024-07-01 Social Science and Humanities Non-Clinical Trial Degree Award
Stephen Bugabo Gumisiriza
ID:
AN ASSESSMENT OF THE EFFECTIVENESS OF GOVERNANCE PRINCIPLES IN COLLABORATIVE FOREST MANAGEMENT FOR THE CONSERVATION OF ECHUYA CENTRAL FOREST RESERVE-SOUTH WESTERN UGANDA
REFNo: SS706ES

To assess how fair benefit sharing under CFM has led to the conservation of Echuya Central Forest reserve

To determine the participation of relevant stakeholders in decision making in CFM for the conservation of Echuya Central Forest Reserve

To determine the recognition and respect for relevant actors in CFM for the conservation of Echuya Central Forest Reserve

 Uganda 2021-07-01 2024-07-01 Social Science and Humanities Degree Award
Timothy  Muwonge Ronald
ID: UNCST-2020-R014680
 ART on the GO: Assessing the impact of mobility on HIV care cascade outcomes in refugee settlements in Uganda
REFNo: HS1197ES

Aim 2: To enroll individuals living with HIV and currently or formerly in HIV care in Nakivale, Palorinya and Adjumani Refugee Settlements in Uganda, and prospectively assess their mobility to evaluate associations between mobility and retention in HIV care.,Aim 1: To prospectively enroll a longitudinal cohort of people newly diagnosed with HIV in Nakivale Refugee Settlement in Uganda and assess the association of mobility and linkage to HIV care.,
 Uganda 2021-07-01 2024-07-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 MID-TERM PROJECT EVALUATION: CAPACITY BUILDING OF NATIONAL TUBERCULOSIS CONTROL
REFNo: HS1253ES

Primary objectives
1. To analyze the matching rate of M-KIT testing results between NTRL and Kumoh National Institute of Technology (KIT).
2. To analyze the change in TB case detection rate in Bukomansimbi from 2017 to 2020

Secondary objectives
1. To analyze the change in TB treatment success rate in Bukomansimbi from 2017 to 2020
2. To analyze the change in TB case notification rate in Bukomansimbi from 2017 to 2020
3. To analyze the change in DOT coverage in Bukomansimbi from 2017 to 2020
4. To analyze the trend of the number of DST performed in NTRL from 2017 to 2020
5. To review the satisfaction of NTRL training program
6. To identify potential activities to incorporate into the ongoing project
Uganda 2021-07-01 2024-07-01 Medical and Health Sciences Non-degree Award
Harriet Kisembo Nalubega
ID:
EFFECT OF CLINICAL IMAGING GUIDELINES ON APPROPRATENESS OF COMPUTERIZED TOMOGRAPHY REQUISITIONS FOR YOUNG PATIENTS IN SIX SELECTED HOSPTALS IN UGANDA
REFNo: HS1313ES

General objective
To assess the effect of CIG on appropriateness of CT requisitions for common CT examinations among young patients in six selected hospitals in Uganda.
Specific objectives:

1.To systematically review literature for barriers and facilitators for guideline implementation in diagnostic imaging with special emphasis to low resource setting
2.To determine the proportion of inappropriate CT requisitions for commonly performed examinations among patients 35 years and below in the six selected hospitals in Uganda

3.To identify the factors contributing to inappropriate Imaging in the six selected hospitals in Uganda
4.To explore the barriers and facilitators of CIGs use in six selected Hospitals in Uganda
5. To determine the proportion of inappropriate CT requisitions for common examinations among patients 35 years and below after introducing the ESR (iGuide) in six selected hospitals in Uganda

Secondary objectives
1.To assess the quality of requisition forms in regard to appropriateness of CT examinations among patients 35 years and below in six selected hospitals in Uganda
2.To measure the base-line (pre-intervention) and the post-training (post intervention) knowledge level of prescribers regarding the use of CIGs in the selected hospitals in Uganda

 Uganda 2021-07-01 2024-07-01 Medical and Health Sciences Degree Award
Sarika Dewan
ID:
Maternal exposure to violence and child malnutrition: a cross-sectional survey in northern Uganda
REFNo: SS845ES

Understand the impact of COVID-19 on maternal well-being and victimization, feeling of safety and access to services,Examine the role of maternal depression as a mediator between violence exposure, nutrition-sensitive behaviour and child malnutrition.,Determine the impact of exposure to violence on maternal nutrition-sensitive behaviour.,Examine the types of violence exposure associated with child malnutrition.,
 Germany 2021-07-01 2024-07-01 Social Science and Humanities Non-Clinical Trial Degree Award
Richard Mallett
ID:
The effects of digital employment on livelihoods, associational life and politics in the urban informal economy: a case study of Kampala’s boda boda sector
REFNo: SS844ES

This proposed research looks at the effects of digital employment on livelihoods, associational life and politics within the urban informal economy – an important area of research lacking serious academic engagement. It aims to do so through an analysis of labour and livelihoods in the motorcycle taxi (or boda boda) sector of Uganda’s capital city, Kampala. Though difficult, dangerous and poorly paid, boda riding nonetheless provides vital work in a context of widespread unemployment, helping a significant share of the urban population make a living in the absence of formal alternatives and safety nets. With the recent arrival of the gig economy, involving app-based motorcycle taxi companies, the nature and organisation of employment in the sector is being reconfigured in uncertain ways and with uncertain effects – testing, amongst other things, the capacity of boda work to absorb urban unemployment. The purpose of the study is to engage critically with the idea that new technologies of employment integrate smoothly and seamlessly into local settings, creating jobs and connecting workers to new economic possibilities in ways that are often perceived to be unproblematic. Instead, it focuses on the challenges that occur as digital innovations come into contact with the urban informal economy, and the unintended consequences that accompany the disruption of people’s livelihoods within it. There are three specific objectives guiding the study, which have been formulated through a review of relevant literature. These are as follows: 1. To examine the effects of digital employment on the livelihoods of riders in Kampala’s boda boda sector 2. To examine the effects of digital employment on the associational and organisational features of work within Kampala’s boda boda sector 3. To examine the effects of digital employment on the relationship between riders in Kampala’s boda boda sector and political actors and processes
UK 2021-07-01 2024-07-01 Social Science and Humanities Non-Clinical Trial Degree Award
Matt Baillie Smith
ID:
Volunteering Together: Blending Knowledge and Skills for Development
REFNo: SS848ES

This research project aims to develop a critical understanding of how different types of volunteers (e.g. community, youth, corporate, national, international and remote volunteers) work together in Uganda. VSO have long carried out their projects using a range of volunteer modalities. They refer to this approach of different types of volunteers working together as “blended volunteering”. The aim of this research is to enhance the understanding of how this “blended approach”, where different types of volunteers work together, can contribute value to the work of VSO Uganda. Beyond that, we expect the research will tell us something about how volunteer modalities may be combined to maximise development impact in other contexts and overall. Furthermore, we will examine relationships between volunteers, primary actors and partner organisations in the field, to capture the wider context within which VSO volunteers work, interact, and deliver development outcomes. Based on our analysis of existing preliminary work as building blocks in this analysis, we have identified significant knowledge gaps in the evidence basis of volunteering and development studies to further explore the concept and practice of blended volunteering: although VSO has observed that blended volunteering can lead to better development outcomes, the exact reason for the impacts of this type of development work remains little understood. Having a fuller understanding of what types of combinations work best, how, when, and why, will not only help VSO deliver higher quality projects and programmes; it will also help them communicate the importance of their development work, and the importance of not just volunteering, but of the particular synergies that emerge when volunteer teams consisting of national, international, and local volunteers with different backgrounds, experiences and skill-sets work together. By ‘volunteer knowledge and skills’ then, we refer not only to individual assets, but also to group assets that emerge from the context in which they work together and the relationships with primary actors and other relevant stakeholders.

Therefore, through this study we aim to better understand: team-focused approaches to volunteering; the programming dimensions of blended volunteering; how different volunteers and primary actors experience blended volunteering approaches; and ‘What works and why’ in the ‘blended volunteering’ model. Furthermore, the research will explore the challenges and obstacles that arise when different types of volunteers and other actors work together, as identified by volunteers, VSO staff and primary actors. This will further help VSO navigate some of these challenges in practice and manage these difficulties as early as the design phase for upcoming projects. This research will thus help VSO develop a deeper understanding on what combination of volunteering and implementation models may be most effective in which specific contexts, and how leveraging these contributions can assist VSO to deliver development impact at scale. This includes understanding the respective strengths and weaknesses of different volunteering modalities in diverse contexts. This presents an opportunity to make a significant contribution to knowledge of volunteering and development, as well as to support innovative programming for ‘blended volunteering’.
 
Based on an extensive literature review and on the experience of VSO Uganda in the field, the general objective of this short-term research project is: To understand how blended volunteering can improve development impacts.
To achieve this objective, we need to understand various areas of the planned and unplanned aspects, outcomes, successes and challenges of VSO’s work. In order to gain a better understanding of this, we divide our main research objective into 4 distinct aims:

(1) Strengthen the evidence base about how combining volunteering modalities has potential to improve programme outcomes (relationships and combinations; impacts);
(2) Deepen understanding of the unique contribution of diverse volunteering modalities, and whether when combined these contribute to enhanced programme outcomes (relationships and combinations; impact);
(3) Understand how the knowledge of diverse volunteering modalities can be designed into VSO programmes to improve outcomes and deliver impact for primary actors (programme design);
(4) Support VSO’s thought leadership by using the findings to influence debates around volunteering and development in policy, practice and academic spaces (impact).

In order to achieve these aims and this main objective, the main research question in this study is the following:
How does different types of volunteers working together improve development impacts?
Our research design is informed by participatory and people-centred approaches and methodologies, as will be described in detail in our methodology section. The study will contribute to policy, practice, and academic understandings in this field by exploring existing examples of blended volunteering contributing to improving development outcomes among VSO Uganda’s portfolio of programmes. Moreover, the study will highlight the potential for further exploring blended volunteering both as a practice and a concept beyond the selected case studies.
 UK 2021-07-01 2024-07-01 Social Science and Humanities Non-Clinical Trial Non-degree Award
Frank Muhereza Emmanuel
ID:
Civil Society in Uganda: Emerging Perspectives and New Narratives.
REFNo: SS694ES

1. To examine the full extent and implications of the rapid expansion of the civil society sector in Uganda
2. To explore the successful initiatives to strengthen the sector and how best to enhance such initiatives
3. To comprehensively explore the contemporary dynamics of the civil society sector in Uganda, and how much the sector contributes to national development.
Uganda 2021-06-30 2024-06-30 Social Science and Humanities Non-degree Award
Mulinde Peterson
ID:
Developing a mobile phones usability and adoption model to promote health among older persons at Kiruddu Hospital
REFNo: HS1305ES

Main Objective
1. To develop a mobile phones’ usability and adoption model for older persons at Kiruddu Hospital.

Specific Objectives
1. To determine key requirements and also investigate the challenges facing mobile phone usability and adoption among older persons at Kiruddu Hospital.
 Uganda 2021-06-30 2024-06-30 Medical and Health Sciences Non-degree Award
Nixon Niyonzima
ID: UNCST-2020-R014577
 Evaluating Tumor Evolution and the Clinical Utility of Circulating Tumor DNA in Patients with Metastatic Breast Cancer Treated with Talazoparib
REFNo: HS1476ES

1. Evaluate mutational changes associated with disease progression in patients with metastatic breast cancer treated with Talazoparib2. Analyse circulating tumor DNA in blood samples collected from metastatic breast cancer patients treated with Talazoparib.3. Determine the association between circulating tumor DNA levels, CA-15-3 levels, and clinical response in patients with metastatic breast cancer treated with Talazoparib.4. Determine the blood-based tumor mutation burden (bTMB) based on WES data generated from samples collected before and after the development of treatment resistance in metastatic breast cancer patients treated with Talazoparib.5. Evaluate the utility of circulating tumor DNA genomic profiling from blood samples collected as dried blood spots from patients with metastatic breast cancer patients and normal age-matched healthy controls.
Uganda 2021-06-30 2024-06-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
EDITH  NAKKU-JOLOBA NAKKU
ID: UNCST-2021-R013931
 Sexual Network Based Tracking and Treatment of Gonorrhea and Chlamydial infections to Improve STD Management in Urban and Rural Uganda: A Pilot Study
REFNo: HS1384ES

Specific Objective 1a; To estimate prevalence of Neisseria gonorheae (NG) in persons attending outpatient clinics in Kampala, Uganda.
Specific Objective 1b; To estimate prevalence of Chlamydia trachomatis (CT) in persons attending outpatient clinics in Kampala, Uganda
Specific Objective 2; To describe the sexual networks of persons diagnosed with Neisseria gonorrhea and Chlamydia trachomatis attending clinics in Kampala, Uganda and the factors influencing these networks.
Specific Objective 3; To describe the bacterial genotypes of infecting Neisseria gonorrhea and Chlamydia trachomatis bacteria identified in these described sexual networks and the related-ness of the bacteria in the identified sexual networks.

 Uganda 2021-06-29 2024-06-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan  Nabadda
ID: UNCST-2020-R014331
 Diabetes Mellitus Tuberculosis and HIV multimorbidities among adult patients attending Kiruddu National Referral Hospital, Uganda Version 2 7/26/2020.
REFNo: HS1386ES

General Objective
The overall objective of this project is to determine the prevalence of DM among patients with either TB, HIV, and TB-HIV co morbidity. This will help to assess the prevalence of silent DM in these categories of patients.
Specific objectives

1. To describe the prevalence of DM among either TB patients or HIV patients or patients with both TB and HIV co morbidity attending the Kiruddu hospital outpatient clinics
2. To determine the factors associated with DM in patients with HIV alone, TB alone and HIV – TB co-infection.

 Uganda 2021-06-29 2024-06-29 Medical and Health Sciences Clinical Trial Non-degree Award
Richard  Ssempala
ID: UNCST-2021-R004837
 Access to Health Care Services in Uganda: The feasible Community health care services delivery model for Uganda.
REFNo: HS1491ES

2. To identify the designs and feasible models for implementing community health care services/ packages in Uganda.,1. To identify the health services/packages provided at community level under the different intervention types.,To review databases of studies that define different delivery mechanisms (models) for the community health services/packages and thereafter recommend a feasible community delivery model(s) for Uganda ,
 Uganda 2021-06-29 2024-06-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Teesta Dey
ID:
Systematic development and validation of a Post-Natal Maternal Self-Assessment Tool for predicting post-natal morbidity in the immediate postpartum period following healthcare facility births in Uganda
REFNo: SS876ES

General Objective To develop a valid, reliable, useful and acceptable post-natal maternal self-assessment tool for predicting post-natal morbidity in health care facilities in Uganda Specific Objectives 1. To explore immediate postnatal care provision, coverage and utilisation in healthcare facilities in Uganda and elicit opportunities to improve care 2. To establish the core content of the tool 3. To create a tool that is culture and setting specific to postnatal Ugandan women 4. To assess the tool for validity and reliability 5. To evaluate the feasibility, acceptability and usability of the post-natal maternal self-assessment tool For each specific objective there are sub-objectives listed within the protocol as attached
 UK 2021-06-28 2024-06-28 Social Science and Humanities Degree Award
David Musoke
ID:
Maximising benefit and minimising the harm of COVID-19 control measures on child and women’s health in Uganda
REFNo: SS881ES

The aim of this research is to assess the negative impact of COVID-19 disease control measures, including lockdown, on child and women’s health in Uganda with diverse pandemic and distinct policy approaches.

Specific objectives
1. Describe the design, evolution and effects of COVID-19 control measures and understand the policies, strategies and measures put in place.
2. Conduct a rapid impact assessment of COVID-19 and its control measures on health systems functioning with a focus on child health and women’s health.
3. Identify interventions, including further research, to optimise COVID-19 control measures.

 Uganda 2021-06-28 2024-06-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
Joshua Musinguzi Bazaale
ID:
Uganda Refugee Population-Based HIV Impact Assessment (RUPHIA 2021)
REFNo: HS1443ES

Primary Objectives
To estimate the following in a household-based, representative sample of adult refugees, aged 15+ years:
1) Prevalence of HIV in adult refugees in Uganda

Secondary Objectives
To estimate the following in the Ugandan refugee population aged 15+ years:

1) Prevalence of HIV viral load suppression (VLS - defined as HIV RNA <1000 copies/milliliter (mL));
2) Prevalence of HIV-related risk behaviors, knowledge, and attitudes;
3) Behavioral and demographic determinants of HIV prevalence;
4) Exposure to, uptake of and barriers to access to HIV-related services;
5) Prevalence of primary and secondary antiretroviral (ARV) drug-resistance (DR) among refugees with viral loads greater than 200 cp/ml;
6) Assess progress towards achievement of the Joint United Nations Programme on HIV and AIDS (UNAIDS) 90-90-90 targets

 Uganda 2021-06-28 2024-06-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
FRED SEMITALA COLLINS
ID: UNCST-2020-R014096
 ENGAGING PRIVATE COMMUNITY PHARMACIES IN EARLY TB CASE FINDING IN KAMPALA, UGANDA
REFNo: SS804ES

1.To understand the perspectives of stakeholders on TB screening to improve early TB case finding at private community pharmacies in Kampala through a formative assessment.
2.To refine components of the proposed intervention to improve early TB case finding at private pharmacies in Kampala, based on findings of the formative research in objective 1.
3.To evaluate the feasibility, fidelity, and acceptability of the intervention to improve early TB case finding at private pharmacies in Kampala using the Reach, Effectiveness, Adoption, Implementation and Maintenance (RE-AIM) framework.

 Uganda 2021-06-25 2024-06-25 Social Science and Humanities Non-degree Award
Christine Begumisa Titianah
ID:
Unmet Need in Essential Medicines and Health Supplies in Ugandan Public Health Facilities.
REFNo: SS886ES

Our first research aims to assess the effect of shortages of selected medicines and health supplies on patients on patients in district-level MOH facilities
The following objectives will facilitate the achievement of this aim:
1. To collect data from health facility registers in order to list 100% of prescriptions written at a representative sample of MOH health facilities over 3 National Medical Stores distribution cycles.
2. To calculate how often filled, unfilled and modified prescriptions affect 100% of patients within selected districts over a 6-month time period, or 3 (as sheduled) National Medical Stores (NMS) cycles, depending on which is longer
3. To compare and contrast the availability of 59 essential medicines throughout each NMS distribution cycles
4. To compare health supply patterns for when medicines are in stock vs. out of stock and describe differences in functioning between medicines and health supplies over 3 NMS cycles.
5. To design and pilot a template approach to tracking data over a six-month period, in order to support continuous improvement in health systems in Uganda.
Our second research aim is to share data on the extent of medicine and health supply shortages with Uganda’s MOH and other stakeholders in order to inform corrective action The following objectives will facilitate the achievement of this aim:
1. To analyse the extent of medicine and health supply shortages within health facilities in MOH over a period of 6 months
2. To provide recommendations that may influence decisions that improve medicine and health supply management, benefit patients, and can be scaled to other regions.
 Uganda 2021-06-25 2024-06-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
Nuwagira Catherine
ID:
Propagation and Growth performance of Schkuhria pinnata L, for Optimal Phytochemical Contents and Antimalarial Activity in Uganda
REFNo: HS1516ES

Main objective
To examine the most viable propagation avenues and growth performance in relation to phytochemical contents and antimalarial activity of S. pinnata in Uganda.
Specific objectives
1. To evaluate agronomic dynamics of S. pinnata under varying climatic conditions of AEZs of Western and South Western Uganda
2. To examine the propagation potentials of S. pinnata through micro-propagation.
3. To evaluate phytochemical components and determine quantitative variations of flavonoids at four developmental stages
4. To determine acute dose and evaluate the plant age effect on antimalarial activity of S. pinnata.


 Uganda 2021-06-24 2024-06-24 Medical and Health Sciences Non-Clinical Trial Degree Award
ONESMUS BYAMUKAMA
ID: UNCST-2021-R013826
 FACTORS ASSOCIATED WITH SHORT INTERDELIVERY INTERVAL AMONG WOMEN WITH ANTECEDENT CESAREAN DELIVERY AT MBARARA REGIONAL REFERRAL HOSPITAL.
REFNo: HS1354ES

1. To determine the proportion of women with a prior antecedent cesarean delivery who present with a short interdelivery interval at Mbarara Regional Referral Hospital.
2. To determine the factors associated with a short interdelivery interval among women delivering at Mbarara Regional Referral Hospital with a prior antecedent cesarean delivery.

 Uganda 2021-06-24 2024-06-24 Medical and Health Sciences Non-Clinical Trial Degree Award
JUSTUS BARAGEINE KAFUNJO
ID: UNCST-2020-R014150
 COMPREHENSIVE REINTEGRATION ASSISTANCE FOR WOMEN WITH FEMALE GENITAL FISTULA: INTERVENTION PILOTING
REFNo: SS890ES

Aim 1: To understand the feasibility and acceptability of a pilot reintegration program for female genital fistula. Aim 2. To assess the acceptability of the pilot reintegration intervention to patients, intervention implementors. Aim 3. To assess the preliminary effectiveness of the pilot reintegration intervention.
 Uganda 2021-06-24 2024-06-24 Social Science and Humanities Clinical Trial Non-degree Award
CHARLES BENSTONS IBINGIRA RUKAMBURA
ID: UNCST-2021-R008521
 : NANOBODY BASED POINT OF CARE DIAGNOSTIC KIT FOR CERVICAL CANCER
REFNo: HS1414ES

This study will to generate and characterise nanobodies for early cervical cancer diagnosis targeting non-invasive biomarkers expressed in urine. Specifically, the study will , 1. Determine the expression levels of cervical cancer discriminatory urine biomarkers at different stages among cervical cancer cases, 2. Generate nanobodies cross-reactive to target cervical cancer specific biomarkers secreted in urine/cervical mucus, and 3. Develop and validate a Nb based lateral flow based multiplex biomarker detection assay for cervical cancer.
Uganda 2021-06-24 2024-06-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Harriet Akello
ID: UNCST-2021-R013785
 Relationship between mental health and health work functioning during the covid-19 pandemic in Uganda
REFNo: HS1407ES

To identify connection between depression, anxiety and stress with health functioning during COVID-19 pandemic ,To determine prevalence of depression, anxiety and stress among healthcare workers during COVID-19 pandemic ,To determine relationship between mental health and health work functioning during covid-19 pandemic in Uganda,
 Uganda 2021-06-24 2024-06-24 Medical and Health Sciences Non-Clinical Trial Degree Award
Jackson Amone
ID:
A usability study on the knowledge and practice of a novel Medium Pressure Reservoir oxygen prototype in Uganda
REFNo: HS1497ES

Phase 2: The primary objective of the usability study is to gather clinical and BMET feedback on the use of the MPR with patients of diverse characteristics and its ability to function through power interruptions &/or in situations where there is high patient volume,Phase 1: The primary objective of the simulated use summative evaluation is to gather evidence of safe and effective use of the device to support regulatory filing.,
 Uganda 2021-06-24 2024-06-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JUDITH NASSAAZI
ID: UNCST-2023-R007664
 LONG TERM EFFECTS OF ORTHOPAEDIC INJURY ON PATIENTS IN UGANDA
REFNo: HS1047ES

General Objective
To determine long-term effects of orthopaedic injury on patients in Uganda 8years following the injury.
Specific Objectives
• To determine the long-term economic impact of tibia and femur fractures on patients and their families
• To determine the health related quality of life of the patients who sustained tibia and femur fractures 8years following their injuries.

 Uganda 2021-06-23 2024-06-23 Medical and Health Sciences Non-degree Award
Kaijuka Benson
ID:
CORPORATE SOCIAL RESPONSIBILITY AND FINANCIAL PERFORMANCE OF SAVINGS AND CREDIT COOPERATIVE SOCIETIES IN UGANDA. A CASE STUDY OF MITOOMA DISTRICT, WESTERN UGANDA
REFNo: SS668ES

The research will specifically tackle the following research objectives; to establish the level of investment made in philanthropic involvement activities on the financial performance of SACCOs in Mitooma district, Western Uganda, to examine the role of investment made in ethical involvement activities on the financial performance of SACCOs in Mitooma district, Western Uganda and to find out how of investment made in economic involvement activities on the financial performance of SACCOs in Mitooma district, Western Uganda.
Uganda 2021-06-23 2024-06-23 Social Science and Humanities Degree Award
Rosalind  Parkes-Ratanshi Parkes
ID: UNCST-2019-R000717
 Characterizing STIs and antimicrobial resistance in men with urethral discharge syndrome in Uganda
REFNo: HS1338ES

Primary:
• To assess and compare the prevalence of pharyngeal STIs (gonorrhea, chlamydia) in relation to urogenital STIs, characterize the antimicrobial resistance (AMR) profile of pharyngeal and urogenital gonorrhea, and identify demographic and behavioral risk factors associated with STIs at different anatomical sites. STIs and AMR profiles will be determined using a combination of traditional laboratory methods (cultures) and molecular approaches, including, but not limited to nucleic acid amplification tests (NAATs).

Secondary:
• To assess acceptability of self-collected tests in men with UDS and pharyngeal testing for STIs in Uganda.
• To estimate the prevalence of 4 STIs in a population of men with UDS caused by the following pathogens: Chlamydia trachomatis (CT), Neisseria gonorrhoea (NG), Trichomonas vaginalis (TV), and Mycoplasma genitalium (MG) using NAATs.
• To estimate the proportion of STIs (CT/NG/MG) at multiple anatomical sites (penis and pharynx (throat))
• To assess the prevalence of HIV and syphilis, and compare HIV result to self-reported HIV status.
• To explore socio-demographic, behavioural and clinical factors associated with positive STI diagnosis and antimicrobial-resistant infections.
• To compare the antimicrobial susceptibility profiles of pharyngeal and urogenital NG isolates recovered the same participant(s).
• To compare the distribution of AMR markers in pharyngeal and urogenital NG.
• To determine the effectiveness of treatment for urogenital NG infections on pharyngeal infections.
• To explore the feasibility of detecting NG and AMR markers using a single-cell molecular approach directly from pharyngeal samples.
• To collect pharyngeal samples for future metagenomics analysis to explore the role of microbiome on pharyngeal NG infections and AMR.
• To explore the role of commensal Neisseria species on the development of AMR in NG.
To provide samples to be added to the Johns Hopkins International STI biorepository at Johns Hopkins School of Medicine, Baltimore, MD USA.


 UK 2021-06-23 2024-06-23 Medical and Health Sciences Non-degree Award
Mohammed Lamorde
ID: UNCST-2019-R001293
 Drug Interactions between Dolutegravir (DTG) and escalating-doses of Rifampicin (RIF) Study
REFNo: HS1376ES

The secondary objectives of the trial are to determine the safety and tolerability of the DTG/RIF combination, the PK of RIF, induction of PgP and CYP3A4 and effect of DTG on appetite,Primary Objective The primary objective of the study is to determine changes to the PK parameters of DTG when administered with standard, medium and high doses of RIF in HIV-negative, TB-monoinfected participants coming to the end of continuation TB therapy with standard doses of RIF and INH over a 10 week period,
 Nigeria 2021-06-23 2024-06-23 Medical and Health Sciences Clinical Trial Non-degree Award
Mark Okwir
ID: UNCST-2021-R013417
 Meningitis: Burden, Causes, Pathogenesis and Prevention in Rural Northern Uganda
REFNo: HS1420ES

Aim 1: To prospectively collect data on all patients with meningitis and meningitis symptoms who were admitted to LRRH to assess etiologies and pathogenesis of meningitis using modern diagnostic testing not previously available and evaluate the causes, burden of disease, and outcomes of meningitis. Aim 2: To perform CrAg screening of 10,000 HIV-positive patients to determine the prevalence of cryptococcal antigenemia and conduct a case control study to compare outcomes among CrAg-positive patients and CD4-matched CrAg-negative controls.
 Uganda 2021-06-23 2024-06-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Olivia Kituuka
ID:
HLA TYPING OF 5 MAJOR ETHNIC GROUPS IN UGANDA AND KNOWLEDGE AND ATTITUDES ABOUT ORGAN DONATION AND TRANSPLANTATION AMONG HEALTH CARE WORKERS, HEALTH POLICY MAKERS AND THE URBAN POPULATION IN UGANDA.
REFNo: HS1447ES

To determine the prevalence of Human Leucocyte Antigen (HLA) sub-types among individuals from five largest ethnic groups in Uganda. ,To assess Knowledge Attitudes and perceptions among urban populations and key stakeholders in Kampala city on organ transplantation in Uganda,
 Uganda 2021-06-23 2024-06-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bernard Kikaire
ID:
Perspectives of stakeholders in research on post-trial access to investigative products: The Post Trial Access (PTA) Study
REFNo: HS1449ES

General Objective
To explore the understanding and perspectives of key research stakeholders about the provision of post-trial access in clinical trials conducted in Uganda.
Specific Objectives
1.To explore research stakeholders’ knowledge of post-trial access in Uganda

2.To explore research stakeholders’ perspectives about post-trial access in clinical trials conducted in Uganda.

3.To describe the post-trial access practices and or experiences among key research stakeholders in Uganda

 Uganda 2021-06-23 2024-06-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Shelley Jones
ID:
Women to Women Research for Economic Empowerment in Uganda: A Participatory Action Research Project
REFNo: SS710ES

The goal of this project is to engage women in Uganda in conducting research that investigates successful community-based, women-led entrepreneurial initiatives in order to inventory, analyze, and report on best practices and lessons learned that will contribute to knowledge that can be accessed by other women who are interested in entrepreneurship. The objectives are to support the participants to 1) develop research skills that will enable them to gain information, knowledge, and insights into how to develop thriving, sustainable initiatives that provide sufficient income to attain and sustain a reasonable standard of living; 2) create and disseminate knowledge around issues directly concerned with women’s empowerment through entrepreneurship
 Canada 2021-06-21 2024-06-21 Social Science and Humanities Non-Clinical Trial Non-degree Award
Sam Ononge
ID: UNCST-2020-R000328
 A PILOT STUDY TO EVALUATE THE PRELIMINARY SAFETY OF THE WEKEBERE SYSTEM FOR THE EARLY DETECTION OF PREGNANCY COMPLICATIONS.
REFNo: HS1025ES

To determine the safety of using the wekebere system in monitoring fetal wellbeing.
To determine the acceptability of the wekebere system among the expectant mothers and clinical staff.

 Uganda 2021-06-18 2024-06-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Irene Andia Biraro Rebecca
ID: UNCST-2019-R001475
 A Randomized Double Blind Placebo Controlled Trial of Rifapentine and Isoniazid for Prevention of Tuberculosis in People with Diabetes.
REFNo: HS1112ES

Primary objective:
To assess the efficacy of preventive therapy with a 12-week course of rifapentine and isoniazid (3HP) against the development of probable or definite TB disease over 24 months in people with Diabetes Mellitus (DM) who are latent TB infection (LTBI) test positive.
Secondary objectives:
• To assess the efficacy of 3HP against the development of possible, probable or definite TB disease over 24-40 months in people with DM who are latent tuberculosis infection test positive
• To compare the proportions who complete treatment between arms
• To compare the occurrence of adverse events between arms
• To compare the rate of TB or death between arms
• To compare the overall mortality rate between arms
• To explore the efficacy of 3HP against development of probable or definite TB in those who are LTBI test positive, across the following sub-groups, separately: study site (n=3); age groups; duration of DM; level of glycaemic control (baseline HbA1C) and body mass index (BMI).
• To assess the efficacy of 3HP against development of probable or definite TB, in two restricted analyses: TST positive and IGRA positive participants.
• To carry out sub-studies including i) an economic modelling and cost effectiveness study, ii) a cohort study of those who are IGRA and TST negative a baseline, iii) a cross-sectional study of HIV and TB prevalence and DM phenotype, (iv) evaluation of point-of care (POC) testing for LTBI, and computer-assisted X-ray, (v) a public health study of patient management, and v) future genetic studies.

Uganda 2021-06-18 2024-06-18 Medical and Health Sciences Clinical Trial Non-degree Award
Elisabeth Vodicka
ID:
Evaluating the ongoing costs and operational context of national HPV vaccine delivery in Uganda
REFNo: HS1358ES

Identify the HPV vaccination program cost drivers and opportunities and challenges for improving cost efficiency.,Evaluate the quality of existing HPV vaccination program performance data.,Understand the contextual factors of the delivery approach for the HPV vaccination program.,Estimate the ongoing costs to deliver HPV vaccines for the health system and supporting platforms (e.g., department of education). ,Evaluate the annual ongoing financial and economic delivery costs for HPV vaccination in Uganda. ,
 USA 2021-06-18 2024-06-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
FRANCIS TUMWESIGYE N/A
ID:
GENDER INCLUSION AND SERVICE PROVISION BY CORE SECURITY AGENCIES IN UGANDA. A CASE OF UGANDA POLICE IN KAMPALA METROPOLITAN AREA.
REFNo: SS779ES

TO EXAMINE THE EFFECTS OF WOMEN PARTICIPATION ON PROVISION OF SERVICES BY THE UGANDA POLICE FORCE.,TO FIND OUT THE BENEFITS OF WOMEN EMPOWERMENT ON PROVISION OF SERVICES BY THE UGANDA POLICE FORCE.,TO ASSESS THE IMPACTS OF WOMEN REPRESENTATION ON EFFECTIVE PROVISION OF SERVICES IN THE UGANDA POLICE FORCE.,TO EXAMINE THE EFFECTS OF GENDER EQUALITY ON EFFECTIVE PROVISION OF SERVICES BY THE UGANDA POLICE FORCE.,THE STUDY OUGHT TO EXAMINE THE EFFECTS OF GENDER INCLUSION AND PROVISION OF SERVICES BY THE UGANDA POLICE FORCE IN THE CONTEPOLARY POLICING.,
 Uganda 2021-06-18 2024-06-18 Social Science and Humanities Non-Clinical Trial Degree Award
Thomas Baik
ID:
A Survey of Language Choice and Code Switching in Psychiatric and Neurological Practice
REFNo: HS1432ES

In this study we aim to explore three situations in which language choice can enhance multilingual patients’ cognitive reserve and psychological resilience. Research in psycho- and sociolinguistics suggests that languages can be used to regulate emotional and social distance. For example, one language can be associated with authority and formality, and other with compassion and solidarity (Myers-Scotton, 1995). This study aims to investigate whether such differential use of languages is also used in medicine and psychotherapy and can be applied to regulate inner emotions. This leads us to our research question: Can multilingualism benefit psychiatric and neurological patients through a mechanism of emotional distance regulation.
We will address language choice and code switching in the context of trauma and psychosis in psychotherapy as well as in the process of neurodegeneration in neurological patients. We aim to address the question of the importance of language choice in illness from all three perspectives of the biopsychosocial model, since each of the above-mentioned groups has one component of the biopsychosocial model in the foreground, meaning that in neurological patients the predominant component is biology, psychosis patients are strongly influenced by psychological factor and in trauma patients the experiences are strongly embedded in social factors.

Germany 2021-06-18 2024-06-18 Medical and Health Sciences Non-Clinical Trial Degree Award
Levicatus Mugenyi
ID: UNCST-2020-R014759
 The Impact of Child-Optimized Financial Education (COFE) Curriculum in Uganda
REFNo: SS817ES

The main study objectives are to answer the following specific research questions/objectives. Outcomes/measures are underlined below. Primary research question: • Does participation in COFE + SILC groups increase the likelihood that caregivers pay for required education expenses of all the school-age children under the caregivers’ care to stay in school vs. participation in SILC only groups? Secondary research questions include: • Does participation in COFE + SILC increase the likelihood that caregivers pay for health-related expenses of all the children under the caregivers’ care (who have a health need) vs. participation in SILC alone? • Does participation in COFE + SILC increase caregivers’ financial self-efficacy vs. participation in SILC alone?
Uganda 2021-06-17 2024-06-17 Social Science and Humanities Non-Clinical Trial Non-degree Award
Damalie Nalwanga
ID: UNCST-2021-R013217
 Exploring understanding, attitudes and practices of frontline health workers and caretakers regarding the relationship between severe pneumonia and malnutrition in children in the context of COVID-19
REFNo: SS803ES

1.To assess the level of understanding of frontline health workers and caretakers regarding the relationship between severe pneumonia and malnutrition in the context of COVID -19
2.To assess the attitudes of frontline health workers and caretakers regarding the relationship between severe pneumonia and malnutrition in the context of COVID -19
3.To assess the practices of frontline health workers and caretakers regarding the relationship between severe pneumonia and malnutrition in the context of COVID -19

 Uganda 2021-06-16 2024-06-16 Social Science and Humanities Non-degree Award
Emmy Okello
ID: UNCST-2020-R009792
 Active Case Detection and Decentralized Dynamic Registry to Improve the Uptake of Rheumatic Heart Disease Secondary Prevention (ADD-RHD)
REFNo: HS1323ES

Primary Objective:
To develop and refine a technology-enabled approach to increase uptake of secondary prevention (ADD-RHD) that is sustainable and replicable at scale to improve outcomes for people living with RHD.

Secondary Objectives:
Aim 1: Optimize the ADD-RHD ACT Platform to maximize case retention and delivery of secondary prophylaxis.
Aim 2: Roll out and evaluate the implementation of the ACT Platform.
Aim 3: Assess the adequacy of current policy and regulatory guidance in Uganda for the adoption of new technologies for health in general, and for rheumatic heart disease diagnosis and management and to describe system and policy constructs necessary for the successful approval of new health technology.
Aim 4: Estimate costs, cost-effectiveness, and budget impact of the ACT platform intervention.

 Uganda 2021-06-16 2024-06-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Julius Okuni Boniface
ID: UNCST-2019-R000963
 A MULTI-COUNTRY, SINGLE-BLINDED, PHASE 2 STUDY TO EVALUATE RAPID DETECTION SYSTEMS OF SARS-COV-2
REFNo: HS1425ES

1. To determine the clinical sensitivity of the test assays compared to the real-time RT-PCR-based method.
2. To determine the specificity of the test assays compared to the real-time RT-PCR-based method.

 Uganda 2021-06-16 2024-06-16 Medical and Health Sciences Clinical Trial Non-degree Award
William Worodria Ofuti
ID: UNCST-2022-R010915
 The effect of household air pollution on lung function recovery in COVID-19 disease
REFNo: SS892ES

Main objective
- The overall aim of the study is to measure the effect of air pollution on lung function recovery after COVID-19 pneumonia.

-Measure the effect of air pollution exposure on lung function recovery after COVID-19.

Specific Objectives

- Measure the effect of mobility on air pollution exposure and lung function recovery after COVID-19.
-
 Uganda 2021-06-16 2024-06-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
Moses  Mulumba
ID: UNCST-2021-R013832
 An Ethnographic Analysis of the Right to Health Based Monitoring of and Advocacy for the Progressive Realization of Universal Health Coverage in Uganda
REFNo: SS793ES

Study Goal

The goal of the project is to establish the extent to which OPERA plus PAR supports the localization of the right to health

Specific objectives
To build the capacity of civil society and influential academia on the use of the OPERA framework

To explore the current levels of enjoyment of the right to health in Uganda

To assess state commitments and efforts to fulfill the right to health including the use of adequate resources

To examine constraints to the state's compliance to fulfill the right to health.
 Uganda 2021-06-14 2024-06-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
Christine  Wiltshire Sekaggya
ID: UNCST-2019-R000578
 Establishing the prevalence of COVID19 infection among patients attending TB clinic, and the effect of COVID19 on TB clinical care in Kampala
REFNo: HS1304ES

Primary objective: 1. To determine the prevalence of COVID-19 infection amongst adult patients attending TB clinics Secondary objectives 1. To determine the prevalence of previous COVID-19 infection amongst adult patients attending TB clinics 2. To explore the experiences of patients attending TB clinic during the COVID-19 pandemic 3. To explore the experiences of healthcare workers in relation to TB care provision during the COVID-19 pandemic
Uganda 2021-06-11 2024-06-11 Medical and Health Sciences Non-degree Award
Arthur Bagonza
ID:
EFFECTIVENESS OF SUPPORT GROUPS ON IMPROVING LIVELIHOOD OF PEOPLE WITH ALBINISM IN UGANDA
REFNo: SS882ES

1. To map and profile all PWA and service providers of PWA in three regions (Northern, Western and Central) Uganda.

2. To construct a model of group support for PWA in three regions of Uganda based on views of PWA.

3. To determine the effectiveness of support groups on increasing access to services and inclusion of People with Albinism in mainstream development processes in Uganda.

4. To explore perceptions of key stakeholders on the use of support groups in increasing access to services and inclusion in mainstream development processes for PWA in Uganda


 Uganda 2021-06-11 2024-06-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
Romeo Gichohi wahome
ID:
EFFECTIVENESS OF IMPROVISED CARDBOARD SPLINTS AS AN ALTERNATIVE TO PLASTER OF PARIS IN THE EMERGENCY TREATMENT OF LOWER LIMB FRACTURES
REFNo: HS1357ES

General Objective
1. To determine whether improvised cardboard
splints are a viable effective
alternative to plaster of Paris splints
for lower limb fractures in Mbarara
Regional and Referral
Hospital.
Specific Objectives
1. To compare the clinical effectiveness of immobilization between improvised cardboard
and plaster of Paris splint in lower limb fractures.
2. To compare the time and resource costs between improvised cardboard and plaster of
Paris in splinting of lower limb fractures.
 Kenya 2021-06-11 2024-06-11 Medical and Health Sciences Non-Clinical Trial Degree Award
Dennis Muhanguzi
ID: UNCST-2019-R001101
 Accelerating Anti-Tick Vaccine Production Using Computational Approaches and Validation with An In-Vivo Model
REFNo: NS165ES

The specific objectives of this study will be to;
i.Create an open access queryable database of candidate anti-tick vaccine protein from I. scapularis proteome
ii.Identify single and chimeric antigenic anti-tick peptides basing on tick-specific amino acid sequences
iii.Evaluate the immunogenicity of five of the most promising antigenic single and chimeric anti-tick peptides in a laboratory animal [three months New Zealand rabbits] model
Uganda 2021-06-10 2024-06-10 Natural Sciences Non-degree Award
Jerome  Kabakyenga Kahuma
ID: UNCST-2021-R013729
 Smart discharges to improve post-discharge health outcomes in children below 6 months old
REFNo: SS855ES

To determine the effectiveness of a Smart Discharge program on post-discharge health seeking behavior and mortality among children under 6 months of age admitted with a proven or suspected infection.
 Uganda 2021-06-08 2024-06-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Musa Sekikubo
ID: UNCST-2021-R014010
 A multi-Centre, randomised, placebo controlled, double-blind, parallel group study to evaluate the safety, tolerability and immunogenicity of two doses of Group B Streptococcus vaccine (GBS-NN/NN2) in women who are pregnant and living with HIV and women who are pregnant and do not have HIV
REFNo: HS1390ES

Objectives
Primary Objectives:
Safety:
To evaluate the safety and tolerability of the GBS-NN/NN2 vaccine in women living with HIV and women without HIV and their newborn babies from vaccination up to delivery/birth.
Immunological:
To compare the transfer rate of vaccine- specific immunoglobulin G (IgG) antibody concentrations from the mother to the baby at birth in women living with HIV with the transfer rate in women without HIV. This endpoint will be used to determine the sample size calculation.
Secondary Objectives
Safety: The safety and tolerability of the GBS-NN/NN2 vaccine in the mother and baby over the first 6 months post-partum, as assessed at 6 months of age.
Immunological: The secondary immunological objectives are:
• To compare IgG antibody responses, specific to the GBS-NN/NN2 vaccine, induced by the first and second vaccine doses over time in pregnant women living with HIV and pregnant women without HIV.
• To evaluate the concentration of IgG antibodies specific for the GBS-NN/NN2 vaccine up to 6 months post-delivery in the mother and baby in women with and without HIV.
• To determine the concentrations of vaccine specific IgG to GBS-NN/NN2 in cord blood at delivery in babies born to women with and without HIV.
Exploratory Objectives
• To compare between groups the isotype composition of the vaccine specific antibodies; in particular IgG and IgA as well as their subclasses, i.e. IgG1-4, IgA1 and IgA2 in maternal and cord blood.
• To compare between groups the vaccine specific IgG antibodies to Rib, Alp1, Alp2 and AlpC, GBS-NN and GBS-NN2 in maternal and cord blood.
• To compare between groups the functional activity of vaccine specific antibodies from cord blood in an opsonophagocytic killing assay (OPkA) and other in vitro assays in selected samples.

 Uganda 2021-06-08 2024-06-08 Medical and Health Sciences Clinical Trial Non-degree Award
Flavia Matovu Kiweewa
ID: UNCST-2021-R013337
 Using Recency Assays to estimate incident HIV infections among Adolescent Girls and Young Women in Hoima and Mityana/Mubende Districts, Uganda Version 2.0 dated 14 April 2021: Gilead Protocol Number :CO-US-985-6117(eStimating hIv incidEnce amoNg Agyw (SIENA) Study)
REFNo: HS1439ES

Primary Objective
i) To estimate the proportion of incident recent HIV infections among AGYWs aged 16-25 years in Hoima and Mityana/ Mubende districts, Uganda.
Secondary Objective
ii) To compare HIV incidence estimated using the Asanté™ HIV-1 Rapid Recency POC kit with that obtained using the Sedia™ HIV-1 LAg-Avidity EIA and the Abbott ARCHITECT HIV Ag/Ab Combo assays.
 Uganda 2021-06-08 2024-06-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sifiso Lukhele Mbhekeni
ID:
GENOMIC EVIDENCE OF THE ROLE OF COMMUNICATION SIGNALS IN MEDIATING REPRODUCTIVE ISOLATION AT CONTACT ZONES
REFNo: NS117ES

1. Identify the threshold of variation in communication signals above which species boundaries are maintained.
2. Determine the importance of divergence time and time since secondary contact on levels of interbreeding.
 South Africa 2021-06-04 2024-06-04 Natural Sciences Non-Clinical Trial Degree Award
Irene Ayakaka
ID:
Feasibility of integrating Leprosy systematic contact follow up and Post Exposure Prophylaxis (PEP) into the Routine Leprosy Control Program in Uganda: A case study of Arua and Koboko districts
REFNo: HS1046ES

Objectives
The overall goal of the study will be to contribute to the elimination of leprosy in Uganda and to describe how best to carry out PEP with Single Dose Rifampicin (SDR) in Uganda.

Specific objectives
1. To assess the feasibility of leprosy post exposure prophylaxis in Arua and Koboko; two high burden districts in Uganda
2. To administer single dose rifampicin to eligible contacts of leprosy patients at their homes
3. To assess the factors associated with successful contact investigation for Leprosy in Arua and Koboko districts
4. To describe opportunities and synergies that can be leveraged in the districts to integrate contact investigation with other on-going community-based activities

Secondary Objectives
1. To perform leprosy data verification in Arua and Koboko districts in Uganda.
2. To assess acceptability of leprosy-contact investigation in households and in the community in Arua and Koboko districts.
3. To document the contribution of contact tracing to early leprosy diagnosis and prevention of grade2 disabilities

 Uganda 2021-06-04 2024-06-04 Medical and Health Sciences Non-degree Award
Danielle Barrington-Francis Jennifer
ID:
Children and their caregivers’ experiences with incontinence
REFNo: SS806ES

3. Prepare and disseminate results, recommendations and methodologies that can be used in developing more holistic, effective and inclusive humanitarian programming.,2. Collect data on attitudes towards and experiences of incontinence from children (aged five to 11), their caregivers and enabling actors through interviews, focus groups and collaborative story book methodology in Adjumani District; and,1. Develop and assess a collaborative story book methodology to engage children (aged five to 11) in humanitarian contexts in discussions of sensitive topics;,
 Australia 2021-06-04 2024-06-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ceriano Mbiika
ID:
Systems Approach to ICT/Telecom Network Energy Management for Sustainability in Sub-Saharan Africa.
REFNo: SIR56ES

• To analyze the strategic, policy and regulatory frameworks employed by other countries and borrow ideas to address energy management challenges for Telecom networks in SSA. • To investigate the weaknesses in the current telecom network energy management approaches across SSA and explore complex emergent properties. • To investigate the effects and influences of economic-socio-ecological factors on the management of telecom power across Sub-Saharan Africa. • To investigate and analyze a suitable methodology and technique from the field of systems thinking that can be applied for problem structuring of current telecom network energy management across SSA. • To formulate a novel framework for guiding the management of sustainable/efficient energy solutions in ICT/Telecom networks across SSA • To use the proposed framework to contribute innovative solutions and suggestions to the energy complex problems in order to achieve holistic benefits to all the energy system’s stakeholders.
 Uganda 2021-06-04 2024-06-04 Engineering and Technology Non-Clinical Trial Degree Award
SABRINA KITAKA BAKEERA
ID: UNCST-2020-R014290
 SEARCH: SMS Electronic Adolescent Reminders for Completion of HPV vaccination in Uganda
REFNo: SS822ES

This protocol is solely for text and voice phone message and intervention development for a subsequent feasibility trial to improve adherence to HPV vaccination schedules in Kampala City., 2: Develop and pre-test HPV vaccine reminders with the target population, 1: Identify desired HPV vaccine text message reminder content (and parallel automated phone reminders) using key informant interviews ,
 Uganda 2021-06-04 2024-06-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
WINTERS MUTTAMBA
ID:
A HEALTH SYSTEMS ANALYSIS AND MODELLING OF METHODS TO MAXIMIZE UPTAKE AND UTILIZATION OF ADVANCED DIAGNOSTICS IN LOW- AND MIDDLE-INCOME COUNTRIES – THE CASE OF COVID-19
REFNo: HS1337ES

1.To quantify the degree of uptake & utilization of COVID-19 diagnostic tests in Uganda, Rwanda, Kenya and UK
2.Map the pathways of uptake and ramping up COVID-19 testing in the study countries.
3.To characterise micro level and macro level factors affecting uptake and utilisation of COVID-19 diagnostic tests in Uganda, Kenya, Rwanda and UK
4.Modelling data obtained in 1) and 2) to identify best models for maximizing uptake of advanced diagnostic tests in health emergencies.
Uganda 2021-06-04 2024-06-04 Medical and Health Sciences Non-degree Award
Ivaibi Charles
ID:
SELECTED CORRELATES OF WORK ENVIRONMENT AND HEALTH SERVICES DELIVERY IN HEALTH CENTRES IN BUSOGA REGION,EASTERN UGANDA
REFNo: SS798ES

(a) To establish the relationship between Support Supervision and Health Services Delivery at Health Centers in Busoga region.
(b) To study the relationship between Physical Work Environment and Health Services Delivery at Health Centers in Busoga region.
(c) To get in-depth information about the relationship between Information Management and Health Services Delivery at Health Centers in Busoga region.
(d) To design a model that will guide effective Health Services Delivery at Health Centers in Busoga region.
 Uganda 2021-06-04 2024-06-04 Social Science and Humanities Non-Clinical Trial Degree Award
Catherine Namuga
ID:
INVESTIGATING THE POTENTIAL OF BIOACTIVE GAUZE DRESSING IMPREGNATED WITH HERB-LOADED NANOPARTICLES IN FACILITATING WOUND HEALING
REFNo: HS1393ES

The main aim of this work is to functionalise the gauze dressing using herb loaded nanoparticles to enable faster wound healing in excision wound models established in rats.

Specific objectives
1) To determine the antibacterial activity of Bidens pilosa L., Hoslundia opposita Vahl and Ageratum conyzoides L., plant extracts.
2) To determine the effect of the most efficacious antibacterial herbal extract on wound healing rate using excision wound models in rats.
3) To determine the effect of nano encapsulation of the herbal extract using biopolymers, on its antibacterial activity and wound healing rate.
4) To evaluate the effect of incorporating herb loaded nanoparticles into the gauze dressing on its antibacterial activity and wound healing rate.
5) To assess the effect of the herb loaded nanoparticles on the performance characteristic of the gauze dressing.

Uganda 2021-06-04 2024-06-04 Medical and Health Sciences Non-Clinical Trial Degree Award
Patrick  Ogwok
ID:
Validation of the food literacy questionnaire among the adult population (18 to 69 years) living in urban Uganda
REFNo: HS1415ES

To evaluate the concurrent validity, assessing capacity of the food literacy questionnaire to distinguish between subgroups with a higher or lower food literacy.,To evaluate criterion validity by exploring associations of the food literacy questionnaire with fruit and vegetable consumption and healthy eating self-efficacy,To evaluate the reliability of a food literacy questionnaire within the adult population (18 to 69 years) living in urban Uganda,To evaluate the construct validity of a food literacy questionnaire against Prime Diet Quality Score within the adult population (18 to 69 years) living in urban Uganda.,To evaluate the face validity of a food literacy questionnaire within the adult population (18 to 69 years) living in urban Uganda ,To evaluate the content validity of a food literacy questionnaire (18 to 69 years) living in urban Uganda,To validate the food literacy questionnaire with respect to healthy eating within the adult population (18 to 69 years) living in urban Uganda. ,
 Uganda 2021-06-04 2024-06-04 Medical and Health Sciences Non-Clinical Trial Degree Award
OTIM   ANYONI GODFREY
ID:
EFFECT OF TILLAGE AND SOIL COVER ON WEEDS IN SMALL HOLDER CONSERVATION AGRICULTURAL SYSTEMS
REFNo: A128ES

1- To compare three seed bank estimation techniques for determining weed seed density and species composition under different tillage practices and soil cover
2- To determine the effect of tillage practice on weed density, diversity and crop performance under CA systems
3- To assess the influence of crop residue and cover crop on weed density, diversity and crop performance under CA systems
4- To determine the effect of the intercrops on overall crop performance under CA systems


 Uganda 2021-06-01 2024-06-01 Agricultural Sciences Non-Clinical Trial Degree Award
Pauline Harding
ID:
Ritual, Identity and Ideology: Constructing the Past in Sub-Saharan Africa
REFNo: SS258ES

I am investigating how the past is manipulated to support present-day ideological agendas in sub-Saharan Africa, in order to understand the ways in which new histories are constructed to reinforce and legitimate group identities and ideologies. I will assess where such constructions ¬– for example at museums, educational institutions and heritage sites, and through intangible heritage displays and local neo-traditional (ritual) activities – reveal disparities between academic renderings of the past and histories that are generated by, and for the use of, the public. I will also assess the active role of heritage sites and intangible heritage practices – and therefore the social responsibilities of archaeologists and heritage workers – in shaping societies in sub-Saharan Africa today; and help archaeologists to recognise and appreciate that the past is evolving in the present, independent of their own work and an aging base of historical knowledge. Uganda is a particularly interesting example of this because, while recent historical work there has been limited, an explosion of newly constructed local histories serves increasingly to distort the historical record. The research will generate important information which will be useful to sites including the Uganda Museum as a source of data and debate as they plan their future development.
 UK 2021-05-28 2024-05-28 Social Science and Humanities Degree Award
Stella Muyanja Zawedde
ID: UNCST-2021-R014037
 Describing the effect of the covid-19 pandemic on tuberculosis care in Uganda
REFNo: SS820ES

To determine the association between access to TB inpatient care services, respiratory symptoms and QoL of patients diagnosed with TB during different phases of the COVID19pandemic,To assess barriers and enablers to accessing TB diagnostic and treatment services during the different phases of the pandemic.,To assess sociodemographic differences between patients accessing TB care services during different phases of the COVID 19 pandemic ,To describe characteristics of patients accessing TB care during different phases theCOVID19 pandemic and to identify enablers and barriers to care seeking during the different phases of the pandemic.,
 Uganda 2021-05-28 2024-05-28 Social Science and Humanities Non-degree Award
Hamson Kanyesigye
ID:
ASSESSMENT OF INTRAPARTUM REFERRALS AND USE OF MOBILE PHONE TECHNOLOGY TO IMPROVE MATERNAL-FETAL OUTCOMES IN SOUTH WESTERN UGANDA
REFNo: HS543ES

General Objective
To assess Maternal Referral processes between Health centre IVs and Mbarara Regional Referral Hospital, and effect of mobile phone technology on maternal and fetal outcomes among referred patients.
Specific objectives
1. To describe patient referral processes between Health centre IV in Isingiro district and Mbarara Regional Referral Hospital.
2. To establish acceptability of phone based intervention among health workers at lower level health units

3. To establish the effect of a phone based intervention on maternal and perinatal deaths among Intrapartum referrals

4. To compare the rates of maternal near-miss conditions and other poor fetal outcomes besides death across study arms

5. To identify the causes of delay following a phone based intervention

 Uganda 2021-05-27 2024-05-27 Medical and Health Sciences Degree Award
EDWINAH ATUSINGWIZE
ID: UNCST-2023-R007893
 Alcohol and Social Media use among university students: Perceptions, patterns and experiences, and the feasibility of social media based interventions for alcohol prevention
REFNo: HS849ES

1. To assess prevalence, patterns and associations of alcohol and social media use among university students
2. To explore university students’ perceptions about alcohol and social media use
3. To explore experiences of university students regarding alcohol and social media use
4. To explore student perspectives on possibilities and opportunities of using social media based interventions for alcohol prevention among university students

Uganda 2021-05-27 2024-05-27 Medical and Health Sciences Non-degree Award
Agapitus Kato Babumba
ID: UNCST-2021-R013866
 Evaluation of the feasibility of SumiShield™ 50WG Insecticide use in the control of malaria vectors in COVID-19 patients’ isolation centres in Uganda
REFNo: HS1256ES

1. To determine the efficacy and residual activity of SumiShieldâ„¢ 50WG insecticide against malaria mosquitoes on plastered and painted wall surfaces in COVID-19 isolation centres in Uganda.

2. To determine the susceptibility of wild Anopheles gambiae mosquitoes to SumiShieldâ„¢ 50WG and other commonly used mosquito insecticides in the study area.
 Uganda 2021-05-27 2024-05-27 Medical and Health Sciences Non-degree Award
Irene Kahimakazi
ID:
Prevalence and factors associated with gestational diabetes mellitus among women attending antenatal care at Mbarara Regional Referral Hospital
REFNo: SS854ES

1. To determine the prevalence of gestational
diabetes mellitus among women attending antenatal
care clinic at Mbarara Regional Referral
Hospital South Western Uganda
2. To establish the factors associated with
gestational diabetes mellitus among women
attending antenatal care clinic at
Mbarara Regional Referral Hospital, south
western Uganda

 Uganda 2021-05-27 2024-05-27 Social Science and Humanities Non-Clinical Trial Degree Award
Phocas Nyandwi -
ID:
Effect of Firm Financial Strength Factors on Income Retention of General Insurers in East Africa
REFNo: SS829ES

To determine the moderating effect of firm size on the relationship between firm financial distress factors and income retention of General insurers in East Africa,To establish the effect of earnings volatility on income retention of General insurers in East Africa,To assess how liquidity affects income retention of General insurers in East Africa,To investigate the effect of leverage on income retention of General insurers in East Africa,To determine the effect of capital adequacy on income retention of General insurers in East Africa,The general objective of the study is to investigate the effect of firm financial strength factors on income retention of General insurers in East Africa.,
 Burundi 2021-05-27 2024-05-27 Social Science and Humanities Non-Clinical Trial Degree Award
Simon Arunga
ID:
Management of microbial keratitis by private pharmacies in Uganda: a study of knowledge, attitude and practice
REFNo: HS1082ES

1. To determine the Knowledge of private pharmacy workers in Uganda in the management of Microbial Keratitis.
2. To describe the current practice for the management of Microbial Keratitis among private pharmacies in Uganda .
3. To explore ways to engage local pharmacy attendants to improve referral of patients with suspected Microbial Keratitis.

 Uganda 2021-05-25 2024-05-25 Medical and Health Sciences Non-degree Award
Dao Ho
ID:
Palliative Care Needs Assessment in the Emergency Department in Kiruddu Hospital
REFNo: SS796ES

Objective 1: Describe the prevalence of palliative care needs among emergency care patients. In order to assess this objective, we will conduct a palliative care needs survey with patients and health care workers in the Kiruddu Hospital Emergency Department. Objective 2: Explore and illustrate identifiable strengths as well as barriers to delivery of palliative care in the emergency department. In order to assess this objective, we will conduct one-on-one interviews with health care workers in the Emergency Department to further explore this topic.
 USA 2021-05-24 2024-05-24 Social Science and Humanities Non-Clinical Trial Degree Award
Gilbert Sendugwa Sendugwa
ID:
Towards Gender Balance: Understanding the Barriers and Solutions to Include Women-Led Businesses in East Africa
REFNo: SS712ES

This research will document policies and practices that exclude and include women-led businesses in Ethiopia, Kenya, Rwanda, Tanzania, and Uganda. Specifically, it aims to: - Understand the participation of and challenges facing women-led businesses and sole proprietorships in the five countries and regionally. - Identify measures being implemented or tested to improve fairness and inclusion of women in public procurement in the selected countries. - Assess the effectiveness of the measures put in place by specific governments to improve fairness and inclusion. - Recommend actionable changes to improve the current situation, based on the findings of the research and international best practice.
 Uganda 2021-05-21 2024-05-21 Social Science and Humanities Non-degree Award
Joannah Nalwoga
ID: UNCST-2024-R002651
 GROUP B STREPTOCOCCUS GENITAL COLONIZATION PATTERNS AMONG NON- PREGNANT WOMEN OF REPRODUCTIVE AGE AT KAWEMPE NATIONAL REFERRAL HOSPITAL
REFNo: HS728ES

General objective
To determine how colonization with GBS changes over time among non-pregnant women of reproductive age and how the changes correlate with the host immunity
Specific objectives
1. To describe how the GBS colonization status changes over a three months period among non-pregnant women who were uncolonized at baseline
2. To describe how the GBS colonization status changes over a three months period among non-pregnant women who were colonized at baseline

3. To determine whether the concentration of GBS IgG in serum correlates with the concentration of GBS IgG at the vaginal mucosa
4. To determine whether we can predict colonization from GBS IgG concentration in blood
5. To determine whether we can predict colonization from GBS IgG concentration in the vaginal mucosa

Uganda 2021-05-20 2024-05-20 Medical and Health Sciences Non-Clinical Trial Degree Award
Hellen Kinyi Wambui
ID:
“Effect of varying ratios of dietary macronutrients on immune system function of Swiss albino mice”
REFNo: NS159ES

i. To assess the effects of varying macronutrient ratios on the nutrition status of Swiss albino mice
ii. To evaluate the effects of varying macronutrients ratios on leucocyte count, neutrophil adhesion and cytokine production of Swiss albino mice
iii. To determine the effects varying ratios of macronutrients on the production of pro-inflammatory (TNF-α, IFN-γ, IL-6) and anti-inflammatory (IL-10) cytokines in Swiss Albino mice challenged with lipopolysaccharide
iv. To evaluate the effects of varying macronutrients ratios on delayed -type hypersensitivity and antibody titers of Swiss albino mice challenged with cow red blood cells (CRBC)

 Kenya 2021-05-20 2024-05-20 Natural Sciences Degree Award
Enock Matovu
ID:
Development and Evaluation of Recombinant SARS-CoV-2 Spike and Membrane Protein-Based Sub-Unit Vaccines
REFNo: NS146ES

(i) To express recombinant subunits of the RBD region of the spike protein and the M protein
(ii) To characterize the humoral and cell mediated immune response generated by the RBD region and the M protein in mouse models
(iii) To determine the safety of the vaccine candidates in mouse models
(iv) To determine the efficacy of the potential candidate vaccine in mice

 Uganda 2021-05-20 2024-05-20 Natural Sciences Non-degree Award
Lena Mpalampa
ID:
FACTORS ASSOCIATED WITH PROVISION OF PHYSICAL ACTIVITY IN PRIMARY SCHOOLS IN MAKINDYE DIVISION IN KAMPALA
REFNo: SS768ES

5. To establish the school related factors associated with insufficient physical activity offered by the primary schools in Kampala during the school term?,4. To establish the class related factors associated with insufficient physical activity offered by the primary schools in Kampala during the school term?,3. To ascertain the teacher related factors associated with insufficient physical activity offered by the primary schools in Kampala during the school term?,2. To describe the various types of physical activity offered in primary schools in Kampala during the school term,1. To determine the proportion of schools offering sufficient time for PA among primary schools in Kampala during the school term,To analyse the factors associated with insufficient physical activity offered in primary schools in Makindye Division in Kampala during the school term.,
 Uganda 2021-05-20 2024-05-20 Social Science and Humanities Degree Award
Katelin Wilton
ID:
Supporting Families through Community Health Workers during COVID: A feasibility and acceptability study
REFNo: SS752ES

Main objective/ purpose
The main objective of this study is to better understand coping strategies of frontline health workers, feasibility and acceptability indicators of messaging success.
Specific Objectives
The specific objectives of this study are to:
• Understand frontline health workers perspective on their stress and psychosocial wellbeing
• Understand the feasibility and acceptability of behaviorally-informed SEL and MHPSS messaging targeted at adult and child clients delivered through frontline health workers
• Determine whether such messaging targeted at clients may also improve frontline health worker coping strategies

USA 2021-05-20 2024-05-20 Social Science and Humanities Non-degree Award
Paul Atherton
ID:
Girls’ Education Challenge Phase II: Continued Access and Learning during Covid-19 in GEC-II PEAS treatment and control schools in Uganda
REFNo: SS764ES

The final research questions for the proposed study are listed below:

a) How have PEAS sought to provide continued access to learning opportunities during school closures?
b) How are the PEAS supporting girls to return to school, and with what effects on girls’ access to learning opportunities?
c) How are PEAS identifying which girls are most at risk of not returning to school? Can a scorecard approach help projects identify those most at risk within projects in a cost-effective way?
d) How have girls’ learning levels changed during the COVID-19 period?

UK 2021-05-20 2024-05-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
WINNIE NAMBATYA
ID:
Evaluation of the complexity of medicine regimens and drug therapy problems among children with sickle cell anemia in Jinja Regional Referral Hospital: A prescription audit
REFNo: HS1299ES

• To determine the complexity of medication regimens prescribed to the patients with SCA.
• To determine the incidence of DTPs among medications prescribed to children with SCA.

 Uganda 2021-05-20 2024-05-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Waiswa Peter
ID: UNCST-2020-R014921
 ALERT – ACTION LEVERAGING EVIDENCE TO REDUCE PERINATAL MORTALITY AND MORBIDITY IN SUB-SAHARAN AFRICA
REFNo: HS1324ES

To develop and evaluate a multifaceted intervention to i) strengthen the implementation of evidence-based interventions and responsive care and ii) reduce in-facility perinatal mortality and morbidity through a multidisciplinary approach in Benin, Malawi, Tanzania and Uganda.
 Uganda 2021-05-20 2024-05-20 Medical and Health Sciences Non-degree Award
Mark Okwir
ID: UNCST-2021-R013417
 Spectrum, Outcomes, and Factors Associated with the Liver disease in a Tertiary Care Hospital, Northern Uganda: a 5 Year Retrospective Study.
REFNo: HS1333ES

General Objectives
To determine the spectrum, outcome, and factors associated with liver disease in patients admitted at Lira hospital in northern Uganda over the last five years.

Specific Objectives:
1. To describe the spectrum of liver disease among patients admitted to Medical wards in Lira Regional Referral Hospital over the last five years.
2. To determine the factors associated with liver disease among patients admitted with liver disease at Lira Hospital in the last five years.
3. Determine the admission outcomes (mortality and survival) of liver diseases among patients admitted at Lira Reginal Referral Hospital in the last five years.
4. To determine the factors associated with the admission outcomes (mortality and survival) of patients admitted with liver disease at LRRH in the last five years.

Uganda 2021-05-20 2024-05-20 Medical and Health Sciences Non-degree Award
SHAMIM NAMUKASA
ID:
Prevalence of Sickle Cell Trait and Needs Assessment for Up-Take of Sickle Cell Screening Among Secondary School Students in Kampala City
REFNo: SS818ES

To explore the stakeholders' perceptions regarding the uptake of sickle cell screening among secondary school students in Kampala City,To Assess the factors influencing uptake of sickle cell screening services among secondary school students in Central Uganda.,To determine the prevalence of sickle cell trait among secondary school students in Kampala City,Determine the prevalence of sickle cell trait among secondary school students and identify student-related and stakeholders' factors influencing up-take of sickle trait screening,3. To Explore the stakeholders' perspectives regarding the uptake of sickle cell screening services among secondary school students in Central Uganda.,2. To Assess the factors influencing uptake of sickle cell screening services among secondary school students in Central Uganda.,1. To determine the proportion of sickle cell among secondary school students in Central Uganda.,
 Uganda 2021-05-20 2024-05-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Grace Lubega Biyinzika
ID: UNCST-2020-R014149
 Perceptions and adherence to preventive measures for Coronavirus Disease 2019 among rural community households in Wakiso district, Uganda.
REFNo: SS819ES

3. To explore community barriers and facilitators of adherence to COVID-19 preventive measures among rural community households.,2. To assess adherence to COVID-19 preventive measures as issued by the Government of Uganda among rural community households.,1. To assess perceptions towards COVID-19 preventive measures among rural community households. ,To assess community perceptions and adherence to COVID-19 preventive measures in rural community households of Wakiso district, Uganda in order to provide essential information needed by public health officials and other stakeholders to make an informed decision on the most effective strategy for reduced community transmission.,
 Uganda 2021-05-20 2024-05-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
MISAKI WAYENGERA
ID:
Prevalence of Polymorphic genes of Alzheimer disease in Nodding disease Tauopathy.
REFNo: HS726ES

To determine if polymorphisms in the eight common genes associated with Alzheimer Disease (APP, MAPT, PREN-1, PREN-2, BACE-1, BACE-2, IDE, and APOE-ε4) are present in DNA of Nodding Disease patients
 Uganda 2021-05-18 2024-05-18 Medical and Health Sciences Degree Award
Obondo Sande James
ID: UNCST-2019-R000241
 Selecting Single Component Adjuvants for Vaccine Formulations
REFNo: HS821ES

1. To determine if adjuvants induce maturation of dendritic cells from healthy donors, LTBI and asymptomatic VL
2. To determine if adjuvants induce antigen-independent proliferation of different lymphocyte populations from healthy donors, LTBI and asymptmatic VL.
3. To measure levels of cytokine production induced by the different adjuvants
4. To determine if adjuvants induce cytotoxicity (as measured by annexin V).

 Uganda 2021-05-18 2024-05-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Richard Idro
ID: UNCST-2021-R013599
 Neurodevelopmental, Behavioural and Physical Growth Outcomes of Children born to Mothers with Nodding Syndrome in Northern Uganda.
REFNo: HS852ES

Primary Objective
To determine the neurodevelopmental and behavioural outcomes of children born to mothers suffering from nodding syndrome compared to children of healthy mothers.

Secondary Objectives
1.To describe adverse medical conditions children of mothers of nodding syndrome have experienced from birth
2.To determine physical growth outcomes among children born to NS patients.
3.To determine the effect of seizure burden (frequency and duration) during pregnancy on child neurodevelopmental outcomes.
4.To determine the effect of caregiver emotional wellbeing on child neurodevelopmental outcomes.

 Uganda 2021-05-18 2024-05-18 Medical and Health Sciences Non-degree Award
Wilson  Tumuhimbise
ID:
A mobile health framework for public private mix in Tuberculosis prevention and care in Uganda
REFNo: HS963ES

1). To explore the barriers and motivators to private hospital engagement in TB care among private healthcare workers with particular focus on understanding the current Public Private Mix frameworks utilized.
2). To develop a mobile phone based framework for enhancing the tracking of TB patients referred from private to public hospitals and assess its initial acceptability and feasibility
3). To assess the preliminary impact of the mobile phone based framework on TB patients’ adherence to referrals for TB diagnosis and treatment in public hospitals.

Uganda 2021-05-18 2024-05-18 Medical and Health Sciences Degree Award
Janet Nakigudde
ID: UNCST-2019-R000444
 Catalyzing Change in Education through a Transformative Learning Collaborative: Scaling-Up of a Social Emotional Learning Curriculum in Uganda A Phase III Randomized Control Trial
REFNo: HS1189ES

Specific Objectives
1. To identify effective strategies to integrate the PD-SEL curriculum into Nakaseke Core Primary Teachers College by applying a learning collaborative approach
2. To carry out additional Professional development adaption of a behavioral management program (PARENT-CORPS) enhancement by integrating teacher/adult SEL training and gender equity. (the PARENT-CORPS program is being adapted at Kibuli CPTC and Bulera CPTC in Hoima but without the SEL component)
3. To evaluate the effectiveness of PD-Enhanced on teachers’ and students’ SEL/SEC when implemented using a task-shifting model with PTC tutors and incorporating a gender-sensitive approach

 Uganda 2021-05-18 2024-05-18 Medical and Health Sciences Non-degree Award
Josephine  Ndagire
ID:
Assessment of Justice Delivery for Children Victims of Defilement
REFNo: SS744ES

The main objective of the research is to assess the response of the justice sector in Uganda to the issue of defilement throughout the justice chain in the last decade and the role that the legal framework particularly the law on defilement (as amended in 2007) has played in facilitating or impeding the actions by the sector and ultimately make recommendations on policy and institutional reforms to address the high defilement rates in the face of strong legal guarantees.
Uganda 2021-05-18 2024-05-18 Social Science and Humanities Non-Clinical Trial Non-degree Award
Steven Ndugwa Kabwama
ID:
Risk Factors for Non-Communicable Diseases among Adults in a District with a High Prevalence of Schistosomiasis
REFNo: HS1289ES

1. To estimate the prevalence of risk factors for NCDs such as alcohol intake, tobacco use, fruit and vegetable intake, obesity and physical activity among adults in Buyende District.
2. To determine the prevalence of schistosomiasis infection among adults in Buyende District.
3. To assess the factors associated with the risk factors for non-communicable diseases (alcohol use, tobacco use, fruit and vegetable intake, obesity) among persons presenting with or without schistosomiasis infection.

 Uganda 2021-05-18 2024-05-18 Medical and Health Sciences Non-degree Award
Johnbosco Turyasingura
ID:
Community participation and sustainability of donar funded potato projects in Kabale district
REFNo: SS758ES

i. To examine effect of project design and implementation of donor funded potato projects in Kabale District.
ii. To determine the effect of project resourcing on sustainability of donor funded potato projects in Kabale District.
iii. To determine the effect of project monitoring and evaluation on the implementation of donor funded potato projects in Kabale District

 Uganda 2021-05-18 2024-05-18 Social Science and Humanities Degree Award
Adeodata Rukyalekere Kekitiinwa
ID: UNCST-2019-R000799
 Novel and Optimized Diagnostics in Pediatric Tuberculosis in Kampala, Uganda(NOD)
REFNo: HS1341ES

The study has the following objectives:
Objective 1: Evaluate and develop novel assays that diagnose TB by detecting Mycobacterium tuberculosis (MTB) bacterial products in non-sputum body fluids. Objective 2: Evaluate and develop novel assays that diagnose TB by detecting host biomarkers in non-sputum body fluids.
Objective 3: Identify combinations of assays that applied together could be used to diagnose TB among children with unconfirmed.

 Uganda 2021-05-18 2024-05-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Edith Wakida K
ID: UNCST-2019-R001225
 Impact and process Evaluation of the Health-Professional Education Partnership Initiative – Transforming Ugandan Institutions Training Against HIV/AIDS
REFNo: HS1351ES

1. To evaluate the acceptability, appropriateness, feasibility, and implementation process of the HIV curriculum
2. To evaluate the acceptability, appropriateness, feasibility, and implementation process of building capacity of primary health care (PHC) providers to provide comprehensive HIV services and strengthen bidirectional linkages between health facilities and communities
3. To evaluate the acceptability, appropriateness, feasibility, and implementation process of the micro-research program

Uganda 2021-05-18 2024-05-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Pontiano Kaleebu
ID: UNCST-2021-R013577
 A phase I study to determine the safety and immunogenicity of the candidate Rift Valley Fever Virus (RVFV) vaccine ChAdOx1 RVF among healthy adult volunteers in Uganda.
REFNo: HS793ES

The primary objective of this study is to assess the safety profile of the candidate vaccine ChAdOx1 RVF in healthy adult volunteers in Uganda. This will be assessed through comparing the frequency of solicited, unsolicited and serious adverse events and changes from the baseline of laboratory safety measures between participants who will receive the active vaccine and those who will receive the placebo.
The Secondary objective is to assess the immunogenicity of the candidate vaccine ChAdOx1 RVF in healthy adult volunteers in Uganda. This will be assessed through quantification of antibodies to the GnGc proteins using ELISA, RVFV neutralising antibody titres and Ex vivo ELISpot and flow cytometry responses to GnGc.
 Uganda 2021-05-17 2024-05-17 Medical and Health Sciences Non-degree Award
Allen Kabagenyi
ID:
Impoverishing and Catastrophic health expenditure on cancer care among persons affected by cancer in Uganda
REFNo: SS851ES

1. To determine the out of pocket expenditure associated with cancer care for persons affected by cancer, by type and stage;
2. To determine the proportion of cancer patients and or their families that experience catastrophic or impoverishing expenditure due to cancer related expenses by cancer type and stage;
3.To characterize the socio-economic interruptions experienced by persons affected by cancer in Uganda.
4.To examine the sociodemographic characteristics associated with cancer care burden in Uganda
5.To assess patients and care givers perceptions and attitudes of cancer care expenditures and health care in Uganda


Uganda 2021-05-17 2024-05-17 Social Science and Humanities Non-Clinical Trial Non-degree Award
Julia Dickson-Gomez
ID: UNCST-2019-R000775
 Integration of buprenorphine into a multi-component harm reduction program for people who inject drugs in Kampala, Uganda
REFNo: HS1229ES

To develop a combination HIV prevention intervention for PWID in Kampala Uganda, using the Consolidated Framework for Intervention Research. The combination intervention includes social network HIV/HCV testing, linkage to care for PWID and PrEP for HIV negative PWID. All participants will be offered safe injection equipment, condoms and HIV risk reduction education, and naloxone, buprenorphine, and CBT4CBT for heroin users.
2. To refine the intervention iteratively through implementation cycles using the CFIR framework to identify barriers and find solutions to implementation and scale-up.
3. To assess feasibility, acceptability and initial promise of the intervention with a 6-month pilot test.

 USA 2021-05-10 2024-05-10 Medical and Health Sciences Non-degree Award
Erisa Mwaka Sabakaki
ID: UNCST-2019-R001625
 Engaging Young People in the Development of Digital Mental Health Innovation in Africa
REFNo: SS795ES

To build a network of experts and stakeholders to develop a framework for responsible and relevant digital mental health interventions for young people in African countries
 Uganda 2021-05-10 2024-05-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
William Worodria Ofuti
ID: UNCST-2022-R010915
 Management of Lower Respiratory Tract Infections in Sub-Saharan Africa, a Pragmatic Approach
REFNo: HS1160ES

Primary objective: To define aetiology and resistance patterns of clinically diagnosed CAP among hospitalized individuals using a comprehensive microbiological approach.

Secondary objectives:
1.To determine the level of agreement between molecular and conventional laboratory testing for the diagnosis of CAP.
2.To determine clinical predictors of treatment outcomes (early treatment failure, mortality) in patients hospitalized with CAP.
3.To determine the role of the CURB-65 severity score and biomarkers (CRP and PCT) in predicting treatment outcomes (early treatment failure, mortality) of patients hospitalized with CAP in a high HIV burden setting.

 Uganda 2021-05-07 2024-05-07 Medical and Health Sciences Non-degree Award
Kenneth Mutesasira
ID:
Patient perspectives and reasons for interruption of TB treatment within central Uganda.
REFNo: HS1383ES

-The overall aim of the study is to understand patient reasons for treatment interruption to inform the interventions for improving TB patient retention and final treatment outcomes.
- The second objective is to explore patient's suggestions for improving their adherence throughout the course of treatment.
 Uganda 2021-05-07 2024-05-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Semitala Fred
ID: UNCST-2020-R014202
 An assessment of current hypertension care (HTN) practices, routines, barriers, and facilitators for people living with HIV at selected health facilities in Kampala and Wakiso Districts in Uganda. A Formative Study
REFNo: SS808ES

Objective 1: To assess for knowledge, attitudes and practices of hypertension management and control.
Objective 2: To document existing guidelines and recommended routines for HTN-HIV integration in HIV clinics.Objective 3: To assess the current practice, routines, barriers and facilitators of HTN-HIV integration in HIV clinics.
Objective 4: To explore key stakeholders’ perspectives on HTN-HIV integration in HIV clinics in Kampala and Wakiso Districts.


Uganda 2021-05-07 2024-05-07 Social Science and Humanities Non-degree Award
James Nyonyintono Mwangwa
ID: UNCST-2023-R005636
 Reporting neonatal demographics, clinical characteristics and outcomes using the deidentified Kiwoko Hospital newborn care unit database
REFNo: SS813ES

Aim 1- Describe demographics, clinical characteristics and outcomes of neonates Aim 2- Describe mortality by birthweight and birth location Aim 3- Evaluate the changes to growth and length of stay after introduction of cue-based feeding in 2019 Aim 4- Evaluate the short-term clinical correlates to a diagnosis of birth asphyxia Aim 5- Determine if frequency of low birthweight admissions correlates to transmission of p. falciparum and decreased use of insecticide treated nets
 Uganda 2021-05-07 2024-05-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
Robert Kalyesubula
ID:
Task Shifting Screening and Measurement of Blood Pressure and Blood Sugars by Community Health Workers for Early Detection and Referral of Hypertension and Diabetes in Rural Uganda.
REFNo: SS821ES

1. To train CHWs in detection, referral, and promotion of continuity for diabetes and
hypertension care among community members in Nakaseke district, Uganda.
2. To assess the ability of trained CHWs to detect and refer patients with diabetes and or hypertension in Nakaseke district.
3. To determine compliance to diabetes and hypertension referral care among community
members in Nakaseke district
 Uganda 2021-05-07 2024-05-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
FREDRICK MAKUMBI
ID:
VACCINATION COVERAGE AND ITS DETERMINANTS AMONG CHILDREN AGED 0 TO 59 MONTHS IN KENYA / UGANDA: A HOUSEHOLD SURVEY
REFNo: HS1391ES

STUDY OBJECTIVES

Broad Objective
The main objective of the baseline and endline surveys is to determine the current status and uptake of immunization services in Living Goods’ focus areas in Kenya and Uganda.
Specific Objectives
The specific objectives of the baseline and endline surveys in Kenya and Uganda are to:
1. Determine the percentage of children (aged 0-59 months) fully vaccinated before and after implementation of the program.
2. Determine the equity or lack thereof in immunization coverage.
3. Assess knowledge, skills (CHWs only) and attitudes of CHWs and caregivers of children aged ≤59 months before and after the intervention.
4. Determine health system factors (stock outs, outreaches, micro-plans, etc.) that facilitate or deter vaccine uptake.

 Uganda 2021-05-07 2024-05-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Josephine Namugumya
ID:
TALENT MANAGEMENT IN UNIVERSITIES IN UGANDA
REFNo: SS681ES

1. To examine the relationship between self-organisation and talent management.

2. To examine the relationship between organisational culture and talent management.
3. To examine the relationship between emotional intelligence and talent management.
4. To examine the relationship between adaptability and talent management

5. To examine the relationship
between self-organisation and Adaptability.
6. To examine the relationship between organisational culture and adaptability.
7. To examine the relationship between emotional intelligence and adaptability.
8. To examine the mediating role of adaptability on the relationship between self -organisation and talent management.

9. To examine the mediating role of adaptability on the relationship between organisational culture and talent management.

10. To examine the mediating role of adaptability on the relationship between emotional intelligence and talent management.
 Uganda 2021-05-05 2024-05-05 Social Science and Humanities Degree Award
Ezekiel Mupere
ID: UNCST-2021-R011972
 Pancreatic Enzymes and Bile Acids: A Non-Antibiotic approach to Treat Intestinal Dysbiosis in Acutely Ill Severely Malnourished Children PB-SAM.
REFNo: HS1193ES

General Objective
• To determine whether treatment with pancreatic enzymes or bile acids reduce mortality in acutely ill hospitalized children with severe malnutrition compared to placebo.

Specific Objectives
To determine:
1. Rate and type of SAEs (including readmissions to hospital)
2. Safety: rate of grade 3 or 4 toxicity events whilst receiving investigational products
3. Intestinal function: number of days with diarrhoea during admission.
4. Use of second and third-line antibiotics during admission and readmission
5. Number of days from enrolment to discharge during admission
6. Growth: (MUAC, weight-for-length, length-for-age) to day 60.

 Uganda 2021-05-05 2024-05-05 Medical and Health Sciences Non-degree Award
Engineer  Bainomugisha
ID: UNCST-2023-R005928
 End-to-end Artificial Intelligence (AI) and data systems for targeted surveillance and management of COVID-19 and future pandemics affecting Uganda (COAST)
REFNo: SIR61ES

1.To strengthen data systems for usable and equitable datasets for AI-driven COVID-19 responses and future pandemics

2.To model and evaluate COVID-19 interventions for targeted government responses.

 Uganda 2021-05-05 2024-05-05 Engineering and Technology Non-Clinical Trial Non-degree Award
Anna Vitali
ID:
Why do firms in Low-Income Countries grow slowly? An Investigation of Demand Side Mechanisms
REFNo: SS711ES

Why do firms in low-income countries grow slowly? My research will provide new evidence on demand-side constraints, that is the challenges that firms face in building a customer base. Specifically, I will study how limited information on product quality restricts the ability of high-quality firms to attract consumers.

Accessing new customers may be especially difficult in developing countries due to high search costs and the lack of institutions that can enforce quality standards. High search costs make it hard for consumers to learn about the existence and the quality offered by different sellers in the market. At the same time, the lack of institutional capacity to enforce quality standards increases the probability of meeting extremely low-quality sellers in the market, thus reducing consumers’ willingness to try out new firms. This type of frictions significantly restricts the ability of high-quality producers to capture customers from lower-quality firm, allowing for the survival of a mass of small, unproductive businesses in the economy.

Customers’ limited ability to observe goods quality can also lead to discrimination against particular groups. For instance, recent studies have shown that individuals tend to underestimate the ability of women relative to men in male-typed domains. If the quality of goods is hard to observe and customers believe that, on average, men have higher ability than women in male-dominated sectors, female entrepreneurs may face significant discrimination from customers when entering male-dominated, high-productivity industries. This could contribute to gender-based employment segregation, one of the leading causes of gender disparity in the labour market.

The findings from my research will shed light on the mechanisms through which policies aimed at improving information on product quality may stimulate firm expansion and employment creation, as well as reduce gender-based employment segregation in low-income economies.

 Italy 2021-04-29 2024-04-29 Social Science and Humanities Degree Award
Tonny Kiyimba
ID:
Dietary pattern and cardio-metabolic profiles of HIV positive Ugandans
REFNo: HS1355ES

3. Assess the association between lifestyle factors (smoking, alcohol consumption and physical activity) and metabolic health of HIV positive Ugandans,2. To assess the association between ART regimen and duration and metabolic health (waist circumference, blood glucose; blood lipid profile – total cholesterol, HDL cholesterol and triglycerides; body composition and blood pressure) of patients with HIV in Uganda,1. To assess the association between dietary intake and metabolic health (waist circumference, blood glucose; blood lipid profile – total cholesterol, HDL cholesterol and triglycerides; body composition and blood pressure) of patients with HIV in Uganda ,To assess the dietary patterns and cardio-metabolic risks of HIV positive Ugandan adults,
 Uganda 2021-04-28 2024-04-28 Medical and Health Sciences Non-Clinical Trial Degree Award
Tumwerinde Emmanuel Aturinde
ID:
Towards a Regendered Military and Women Participation in the AMISOM
REFNo: SS723ES

i. Explore the nature of gender relations in the military institution and its influence on selection, training and deployment of women in peace operations
ii. Analyse the history of women participation in peace operations with reference to the Kenya and Uganda as AMISOM Troop Contributing countries
iii. Examine the roles and experiences of women combatants in peace operations.
iv. Analyse how women participation and experiences in peace operations have contributed to change in gendered military relations in the context anti-antiterrorism Missions.

Uganda 2021-04-27 2024-04-27 Social Science and Humanities Degree Award
Victoria Namuggala Flavia
ID: UNCST-2019-R000991
 The gendered price of precarity. Young women navigating workplace sexual harassment.
REFNo: SS608ES

Principal aim
The principal aim of the project is to contribute to an understanding of the processes of empowerment of young females in response to (vulnerability to) WSH, in order to inform policy directions and civil society efforts aimed at empowering young workers.

Specific objectives are:
1) To contribute to a better understanding of processes of gaining voice and empowerment in response to WSH in different precarious labour settings, by highlighting variation between the formal and informal sector.
2) To contribute to empirical knowledge about WSH in sectors for which limited research exists, and from a youth perspective.
3) To raise awareness among relevant policy actors about the specific conditions that create vulnerability to WSH for young women working in selected formal and informal sectors, and help them design strategies to address this within employment interventions.
4) To contribute to policy development for addressing sexual harassment in the informal sector, in support of implementing Article 8 of ILO Convention 190.
5) To contribute to the development of an ‘everyday language’ in local vernacular in Uganda and Bangladesh, which policy actors, civil society, and young women can comfortably use to articulate WSH.

 Uganda 2021-04-27 2024-04-27 Social Science and Humanities Non-degree Award
Olivia Kituuka
ID:
INFORMED CONSENT PROCESS FOR EMERGENCY SURGERY AT PUBLIC AND PRIVATE HOSPITAL SURGICAL EMERGENCY UNITS IN THE URBAN UGANDAN SETTING
REFNo: HS1208ES

i. To explore and describe patients’ experiences and satisfaction with the informed consent process for emergency surgery, at both public and private not for profit teaching hospitals in Uganda
ii. To explore the roles, perceptions and experiences of the next of kin of patients who have undergone emergency surgery on the informed consent process at both public teaching hospital and private not for profit teaching hospitals in Uganda.
iii. To determine the factors that influence informed consent practices of emergency department staff involved in the informed consent process for emergency surgery in public and private not for profit teaching hospitals in Uganda

 Uganda 2021-04-27 2024-04-27 Medical and Health Sciences Degree Award
Jenna Grzeslo
ID:
Exploring the Feasibility of Empowerment and Livelihood for Adolescents (ELA) in an Afterschool Setting: Formative Research to Inform Programming and Policy in Uganda
REFNo: SS693ES

1. BRAC would like to explore the feasibility of school and government uptake of the programming.

2. Finally, to inform future experimental evaluations, we seek to understand the role of dosage (e.g., the number and frequency of meetings) in designing the updated ELA curriculum.
USA 2021-04-27 2024-04-27 Social Science and Humanities Non-degree Award
Pakoyo Kamba Fadhiru
ID:
A prospective cohort study of oral morphine self-medication by caregivers of paediatric patients at Mulago National Referral Hospital, Kampala
REFNo: HS1331ES

To determine the effect of diversion of patients’ oral morphine by caregivers on their health related quality of life and that of patients in paediatric clinics at Mulago National Referral Hospital,To determine the prevalence and compliance with necessary written internal controls for prescribing, dispensing and administration of oral morphine by paediatrics clinics at Mulago National Referral Hospital,To determine the effect of home-based oral morphine use in palliative care on drug use disorders among caregivers of paediatric patients at Mulago National Referral Hospital. This will be achieved by comparing the prevalence and incidence of self-medication with oral morphine and other controlled drugs between caregivers of paediatric patients with and without prescribed oral morphine.,To determine the factors associated with self-medication with oral morphine among caregivers of paediatric patients on prescribed oral morphine in paediatrics clinics at Mulago National Referral Hospital,To determine the prevalence and incidence of self-medication with oral morphine among caregivers of paediatric patients on prescribed oral morphine in paediatrics clinics at Mulago National Referral Hospital. This will be achieved through a baseline survey of prevalence followed by longitudinal evaluation of incidence of self-medication at endline.,To understand the compliance of paediatric clinics with oral morphine controls and the effect of diversion of patients’ oral morphine by caregivers on the quality of life of paediatric patients and caregivers,4. To determine the effect of diversion of patients’ oral morphine by caregivers on their health related quality of life and that of patients in paediatric clinics at Mulago National Referral Hospital.,3. To determine the prevalence and compliance with necessary written internal controls for prescribing, dispensing and administration of oral morphine by paediatrics clinics at Mulago National Referral Hospital.,2. To determine the effect of home-based oral morphine use in palliative care on drug use disorders among caregivers of paediatric patients at Mulago National Referral Hospital. This will be achieved by comparing the prevalence and incidence of self-medication with oral morphine and other controlled drugs between caregivers of paediatric patients with and without prescribed oral morphine.,1. To determine the prevalence and incidence of self-medication with oral morphine among caregivers of paediatric patients on prescribed oral morphine in paediatrics clinics at Mulago National Referral Hospital. This will be achieved through a baseline survey of prevalence followed by bimonthly longitudinal monitoring of incidence of self-medication.,
 Uganda 2021-04-27 2024-04-27 Medical and Health Sciences Non-degree Award
Sophie Mylan Katherine Hardman
ID:
Epidemics in Refugee Settlements: An ethnographic exploration of ‘Preparedness’ in Palabek Refugee Settlement, Northern Uganda, during times of COVID-19
REFNo: SS745ES

The objective of this study is to understand how epidemic ‘preparedness’ in refugee settlements can pay greater attention to histories, ideas and practices from refugees themselves. Through ethnographic research, including, but not restricted to, fieldwork in Palabek Refugee Settlement, northern Uganda, during times of COVID-19, the connections and disconnections between global policy, biomedical approaches, and ‘preparedness from below’ will be explored as equal objects of study.
 UK 2021-04-27 2024-04-27 Social Science and Humanities Degree Award
Eugene Ruzagira
ID: UNCST-2023-R008282
 PRELIMINARY INVESTIGATIONS TO SUPPORT COVID-19 VACCINE ROLL-OUT IN UGANDA [CO-ROLL]
REFNo: SS767ES

The study objectives are
1. To assess uptake of COVID-19 vaccination and associated factors among HCWs and older (>50 years) persons in Uganda
2. To describe the knowledge and attitudes towards COVID-19 vaccines among HCWs and older (>50 years) persons in Uganda
3. To describe the profile of anti-SARS-CoV-2 IgG antibodies before and after vaccination in HCWs and older (>50 years) persons in Uganda.
4. To describe cellular immune responses to SARS-CoV-2 antigens before and after vaccination in HCWs and older (>50 years) persons in Uganda.
5. To describe pre-COVID-19 immunisation innate response profiles, and relate these to the antigen specific vaccine responses in HCWs and older (>50 years) persons in Uganda
6. To determine the social and structural factors that influence uptake of COVID-19 vaccines in HCWs and older (>50 years) persons in Uganda

 Uganda 2021-04-27 2024-04-27 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ronald Mangeni
ID:
Utility of pooled sputum samples for Tuberculosis screening in a high TB burden setting.
REFNo: HS1329ES

- The overall aim of this study is to determine sensitivity and specificity of pooled sputum samples in the diagnosis of TB in a healthcare setting in Uganda

Secondary objectives
- To determine the effect of varying bacterial loads on the sensitivity and specificity of sputum pooling
- To determine the effect of different pooling ratios on the sensitivity and specificity of sputum pooling
 Uganda 2021-04-27 2024-04-27 Medical and Health Sciences Non-degree Award
FREDRICK MAKUMBI
ID:
Understanding how information on abortion is shared in social networks: a mixed-methods follow up study to refine two social network-based methods for measuring abortion incidence
REFNo: SS814ES

This study aims to understand how information on pregnancy termination is shared within social networks and use this information to assess and improve the use of two social-network based methods for estimating abortion incidence.

Specific objectives
(1) Improve the robustness and accuracy of the estimate of abortion incidence in Uganda
(2) Assess how diffusely information about pregnancy termination is shared within women’s social networks in Uganda
(3) Provide detailed information on the timing and purpose of pregnancy termination disclosure

Uganda 2021-04-27 2024-04-27 Social Science and Humanities Non-degree Award
Martha Mulerwa
ID:
Inter-rater reliability and comparison of the repeatability of four different approaches to setting up goniometers and torsiometers to measure forearm and wrist kinematics.
REFNo: SIR60ES

General objective: Compare the four different approaches to setting up an electro-goniometer and torsiometer listed above in order to determine the most appropriate procedure for wrist kinematics measurements.

Specific Objectives:
To evaluate the repeatability of the four setup procedures
To evaluate inter-rater reliability when setting up the electro-goniometer and torsiometer using the four setup procedures during wrist kinematics
To evaluate intra-rater reliability when setting up the electro-goniometer and torsiometer using the four setup procedures during wrist kinematics

 Uganda 2021-04-27 2024-04-27 Engineering and Technology Non-Clinical Trial Degree Award
Chaning Jang Ahn Wong
ID:
Contextualizing Moral Foundations Theory for Better Messaging in Uganda
REFNo: SS797ES

General Objective:
This study seeks to contextualize the Moral Foundation Theory to the Ugandan context through various instruments to have a better understanding of the social, and personal values of its population.
Specific and Achievable Objectives:
The breakdown of the general objective of this project is as follows:
Adapt the moral foundation research process, as laid out by Knutson and Haidt, to the Ugandan context through exploratory and confirmatory analysis
Diagnose the distribution of moral decision-making across five themes by examining respondents’ classifications of moral violations.
Seeking to understand how the foundations are distributed across the general population.
Use the validated set of moral foundations to inform behavioral change communication/messaging campaigns.

USA 2021-04-27 2024-04-27 Social Science and Humanities Non-Clinical Trial Non-degree Award
Enock Matovu
ID:
Development of Indirect Enzyme Linked Immunosorbent Assay [ELISA] for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2) Surveillance in Uganda
REFNo: HS1382ES

i. To evaluate commercially available formulations of the spike and nucleocapsid antigens derived from E. coli, insect and human cell expression systems to determine the best performer
ii. To determine the diagnostic sensitivity and specificity of the spike and nucleocapsid antigens-based indirect ELISA for diagnosis and community sero-surveillance of SARS-COV2

 Uganda 2021-04-27 2024-04-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Roy Mayega William
ID: UNCST-2022-R010983
 Differences in the formation and development of informal settlements and their effects on residents’ health and safety.
REFNo: SS715ES

General objective
The objective of the proposed research is to conduct formative research in Kampala, Uganda as part of a larger research agenda to compare informal settlements in four countries in East Africa, Uganda, Rwanda, Tanzania and Kenya to determine how history of formation, government strategies to improve settlements and the kinds of improvements that have been made affect the health and well-being of residents.
Specific objectives
Specific objectives of the proposed research include the following.
1. To explore how informal settlements in Kampala, Uganda are formed and how this may cause differences in the settlement’s health hazards.
2. formal To explore strategies that Uganda has taken to improve informal settlements and the health effects of these efforts for the families and children who live in informal settlements.
3. To qualitatively identify the most pressing health needs of families and children in the selected informal settlements within Kampala.

Uganda 2021-04-26 2024-04-26 Social Science and Humanities Non-degree Award
John Storey Douglas
ID:
Understanding factors that influence people's health-seeking behavior to inform a social and behavior change communications campaigns in Uganda
REFNo: SS761ES

The overall objective of this research is to suggest ways of improving the OBULAMU brand and to develop a set of recommendations
to inform a national-level social and behavior change communication strategy for the Ministry of Health in Uganda. In order to achieve this objective, the following smaller objectives will be met:
a)To identify the characteristics and behaviors of different brand users.
b)To understand the barriers and levers to improve past communication efforts.
c)To understand baseline attitudes, perceptions and the socio-ecological context which influences users' health-related decisions.
d)To identify the critical moments in people’s lives across which different health needs become salient
e)To design and test solutions to address the barriers faced by end-users and provide holistic recommendations that can inform the redesigning efforts of the OBULAMU campaign and provide inputs into the national SBC strategy.

 USA 2021-04-26 2024-04-26 Social Science and Humanities Non-degree Award
Gerald Mboowa
ID:
Assessing knowledge, attitudes, perceptions, and skills towards the use of face masks: A community-level perspective
REFNo: SS489ES

i. To assess knowledge, attitudes, and perceptions towards the use of face masks by high- risk groups in Kampala district, Uganda.
ii. To assess skills towards the use of face masks, evaluate the face masks for safety and fitness-for-use, and provide a classification for those commonly circulating on the Ugandan market.
iii. To educate and skill high- risk groups in Kampala district on the rational use and disposal of face masks.

 Uganda 2021-04-22 2024-04-22 Social Science and Humanities Non-degree Award
Lillian Tindyebwa --
ID:
Gender Dynamics - Analysis of Convicts in selected Prisons in Kigezi Region
REFNo: SS521ES

1. To explore gender dynamics of crimes for convicts in major prisons at selected districts in the Kigezi region
2.To identify types of crimes committed by men and women convicts in major prisons in the Kigezi region
3. To establish the gendered patterns formed in committing crimes by convicts in major prisons in the Kigezi region.
4.To explore the underlying motives to commit various crimes by the convicts in major prisons at districts in the Kigezi region.
5.To establish the influence of community that could cause the person to commit a crime.
 Uganda 2021-04-22 2024-04-22 Social Science and Humanities Non-degree Award
Anthony Kadoma
ID:
Understanding stakeholder perceptions on wetland ecosystem services to support conservation and restoration activities
REFNo: SS705ES

To establish past, present, and future wetland conservation and restoration activities in Wakiso district

Identify the stakeholders involved and their roles and motivations

Document and analyze the perceptions stakeholders have on wetland ecosystem services and

To synthesize stakeholders' perceptions and their integration into wetland conservation and restoration activities.
Uganda 2021-04-22 2024-04-22 Social Science and Humanities Degree Award
Moffat  Nyirenda Joha
ID: UNCST-2020-R019333
 Understanding differential effects of lipid lowering agents on lipid isoforms: a multi-center retrospective study in Uganda
REFNo: HS1292ES

a. To determine the patterns of dyslipidaemia among patients who present with dyslipidaemia at primary care and specialist hospitals in Uganda
b. To describe the patient characteristics that are associated with different patterns of dyslipidaemia
c. To determine the commonly used lipid lowering agents
d. To examine the differences in response to lipid lowering therapy
e. To determine the proportion of optimal control among individuals taking lipid-lowering agents
f. To examine the times to optimal LDL-C control among individuals taking lipid-lowering agents

 Malawi 2021-04-22 2024-04-22 Medical and Health Sciences Non-degree Award
Elizabeth Brannon Lynn
ID:
The Role of Former Female Fighters in the National Resistance Movement
REFNo: SS791ES

During conflict, women step into a number of roles that were traditionally reserved for men--with some women joining rebel forces to fight, others taking up peace activism to combat such fighting, and many stepping into roles that were traditionally held by men. A strong literature has emerged detailing women's violent participation in conflict, as well as the motivations, dynamics, and implications of their action. Through their participation, women are able to experience greater equality with men, in addition to building critical skills and networks. However, little is known about how former rebel women build on these experiences post-conflict. Instead, much of the literature suggests that former rebel women experience significant marginalization after conflict, minimizing their future opportunities. Such patterns seem further at odds with patterns of rebel-group-to-political-party transformations. In this project, I have two main objectives. I seek to understand the post-conflict fate of former female fighters and how it relates to former rebel party politics. I ask if and how former female fighters are able to build on their conflict experiences and networks to access positions of political power in the post-conflict environment. Further, I seek to understand broader patterns in which women are elected after conflict. To understand these dynamics, I intend to collect systematic candidate data in Uganda and will complement this will a qualitative analysis based on interviews with former female combatants for the National Resistance Army.
 USA 2021-04-22 2024-04-22 Social Science and Humanities Non-Clinical Trial Degree Award
Anthony Mugeere Buyinza
ID:
PEAK YOUTH, CLIMATE CHANGE AND THE ROLE OF YOUNG PEOPLE IN SEIZING THEIR FUTURE
REFNo: SS670ES

General Objective:

To explore how climate change in Uganda is affecting young lives and youth livelihoods in the regions of Karamoja and Jinja.

Specific objectives:
(i) To document the diverse lives and livelihood strategies of young people
in rural and urban settings;
(ii) To find out how climate change impacts upon young people's lives and livelihoods;

(iii) To identify youth solutions to the challenges they face.
 Uganda 2021-04-21 2024-04-21 Social Science and Humanities Non-degree Award
Elizabeth Ayebare Ombeva
ID: UNCST-2020-R003666
 An education package to improve health worker communication with women and families after stillbirth or neonatal death: A feasibility study
REFNo: HS1102ES

1. To pilot an education package and associated resources, including train the trainer/training manuals and audio-visual aids to improve health worker communication in Malawi, Uganda, Zambia and Zimbabwe.
2. For feasibility
a. Explore the acceptability and implementation of the package with facility staff receiving training, trainers and service managers across settings.
b. Explore the acceptability and implementation of the package with undergraduate midwifery students receiving training.
c. Assess uptake and attendance/completion of the package.
d. Explore impacts of the research and education package on practice and clinical services.
3. To prepare for a full-scale evaluation:
a. Define the most appropriate primary and secondary outcomes to assess the effect of the educational package on health workers’ communication and parents’ experiences.
b. Assess the acceptability and burden of data collection for participants.
c. Use data to optimise the design and estimate the sample size for a full-scale trial.
d. Exploration of key resources associated with implementing the educational package will be completed to provide an economic understanding of the intervention and its potential impact.
e. To utilise existing and develop additional networks to identify potential sites for a full-scale trial.
4. To combine the feasibility, acceptability and uptake data to develop a full trial protocol by the end of the study.

 Uganda 2021-04-21 2024-04-21 Medical and Health Sciences Non-degree Award
Nixon Niyonzima
ID: UNCST-2020-R014577
 SARS-CoV-2 seroconversion: a sero prevalence study among cancer patients and health workers at the Uganda Cancer Institute
REFNo: HS1240ES

3. To describe the temporal trends in the anti- SARS-CoV-2 antibody sero-prevalence among cancer patients at the Uganda Cancer Institute,2. To describe the clinical and demographic characteristics associated with history of exposure to SARS-CoV-2 and severity of COVID-19 disease in cancer patients. ,1. To determine SARS-CoV-2 antibody sero-prevalence in cancer patients attending care at the Uganda Cancer Institute,
 Uganda 2021-04-21 2024-04-21 Medical and Health Sciences Non-degree Award
Conrad Muzoora Kihembe
ID: UNCST-2019-R001432
 A randomized clinical TriaL of early empiric Anti-Mycobacterium tuberculosis therapy for Sepsis in sub-Saharan Africa (ATLAS trial)
REFNo: HS1272ES

The primary hypothesis of this clinical trial protocol is that immediate and sepsis specific dose of anti-TB therapy will result in improved 28-day mortality for study participants admitted to hospital with HIV and sepsis in Tanzania and Uganda compared to standard care alone.

The primary objective is:
1) To conduct a randomized 2x2 factorial clinical trial of 1) immediate initiation of empiric anti-TB therapy plus standard care vs diagnosis dependent anti-TB therapy plus standard care alone and 2) sepsis-specific anti-TB therapy plus standard care vs conventional WHO weight-based anti-TB therapy plus standard care for patients presenting with sepsis to two hospitals in Uganda and Tanzania.
1a) To determine if empiric immediate initiation of anti-TB therapy plus standard care improves 28 day mortality compared to diagnosis dependent anti-TB therapy plus standard care.
1b) To determine if sepsis-specific dose anti-TB therapy plus standard care improves 28 day mortality compared to conventional WHO weight-based anti-TB therapy plus standard care.

The secondary objectives include:
1) To determine if empiric immediate initiation of anti-TB therapy plus standard care improves in-hospital mortality compared to diagnosis dependent anti-TB therapy plus standard care
2) To determine if sepsis-specific dose anti-TB therapy plus standard care improves in hospital mortality compared to conventional WHO weight-based anti-TB therapy plus standard care.
3) To determine if empiric immediate initiation of anti-TB therapy plus standard care improves 6 month mortality compared to diagnosis dependent anti-TB therapy plus standard care
4) To determine if sepsis-specific dose anti-TB therapy plus standard care improves 6 month mortality compared to conventional WHO weight-based anti-TB therapy plus standard care.
5) To determine the safety of increased dose anti-TB therapy for patients with sepsis
6) To determine if early achievement of target serum drug concentrations of isoniazid and rifampin, measured at day-2 of TB treatment, associates with more rapid clinical improvement among patients with confirmed TB.

 Uganda 2021-04-21 2024-04-21 Medical and Health Sciences Non-degree Award
Harriet Mayanja-Kizza
ID: UNCST-2021-R013074
 A Survey Assessing Male Reproduction During or After Treatment Containing Pretomanid
REFNo: HS1340ES

To evaluate the paternity status in male participants who have received a pretomanid containing regimen in one of the following TB Alliance clinical trials: STAND, Nix-TB, SimpliciTB or ZeNix.
 Uganda 2021-04-21 2024-04-21 Medical and Health Sciences Non-degree Award
Freddy Kitutu Eric
ID: UNCST-2020-R014751
 Using community influencer groups to address COVID-19 misinformation and vaccine hesitancy in Buikwe, Uganda
REFNo: HS1140ES

The evaluate the effect of community influencer groups on COVID-19 misinformation and potential COVID-19 vaccine hesitancy.,To form and empower community influencer groups against COVID-19 misinformation and potential COVID-19 vaccine hesitancy ,To explore the effect of COVID-19 misinformation on potential hesitancy towards a future COVID-19 vaccine,To determine the prevalence of potential hesitancy to a future COVID-19 vaccine in Buikwe,To determine the prevalence of COVID-19 misinformation in Buikwe,
 Uganda 2021-04-15 2024-04-15 Medical and Health Sciences Non-degree Award
Noleb Mugisha Mugume
ID:
Integrating cervical cancer screening in HIV clinics and assessing the effect of using a modified referral protocol on access to cancer services among HIV-positive women in Uganda
REFNo: HS1219ES

Major objective: To assess the effect of a modified referral protocol on access to cancer services among HIV-positive women with positive cervical cancer screening findings and describe acceptability of integrating cervical cancer screening services in HIV clinics and referring women with positive screening results using the modified referral protocol.

Specific objectives
1. To assess the effect of using a modified referral protocol on access to cancer services among HIV-positive women with positive cervical cancer screening findings.

2. To describe experiences of HIV-positive women and health care providers with implementation of integrated cervical cancer screening services in HIV clinics and referral using a modified referral protocol

3. To describe acceptability of a program that provides integrated cervical cancer screening services in HIV clinics to women presenting for routine HIV care and links those with positive screening findings to cancer care services using a modified referral protocol among health care providers and mangers in the clinics.

 Uganda 2021-04-15 2024-04-15 Medical and Health Sciences Degree Award
victoria nakibuuka
ID: UNCST-2020-R014741
 Developmental care packages to improve neonatal outcomes – a multidisciplinary approach
REFNo: HS1254ES

To survey current knowledge, practices and attitudes towards developmental care to assess potential barriers and facilitators to implementing and integrating developmental To observe current practice in NICU’s care packages in NICU’s in LMIC

 Uganda 2021-04-15 2024-04-15 Medical and Health Sciences Non-degree Award
Cissy  Kityo
ID: UNCST-2021-R013663
 D3 (PENTA 21) A randomised non-inferiority trial with nested PK to assess DTG/3TC fixed dose formulations for the maintenance of virological suppression in children with HIV infection aged 2 to <15 years old
REFNo: HS1288ES

The overall aim is to evaluate two-drug therapy with DTG/3TC FDC given once daily in comparison with triple-drug ART in HIV-1 infected children and adolescents who are virologically-suppressed on their ART regimen.

PRIMARY OBJECTIVE
To assess whether DTG/3TC is non-inferior to SOC, consisting of an anchor drug (NNRTI, PI or INSTI) and 2 NRTIs, in terms of virological suppression

HYPOTHESIS
Switching to DTG/3TC will provide non-inferior virological suppression to remaining on SOC over 96 weeks.

SECONDARY OBJECTIVES
 To evaluate clinical and laboratory adverse events associated with the trial antiretrovirals
 To evaluate new resistance mutations in participants with virological rebound (confirmed VL≥50 copies/mL)
 To assess low level viraemia and virological reservoirs
 To evaluate adherence, tolerability, acceptability, sleep and health-related quality of life
 To evaluate and model the pharmacokinetics and pharmacodynamics of dispersible and film-coated fixed-dose DTG/3TC formulations in children weighing 6-<40kg using WHO weight band-aligned dosing
 To evaluate cost-effectiveness of treatment maintenance with DTG/3TC FDC if DTG/3TC is shown to be non-inferior to SOC

Uganda 2021-04-15 2024-04-15 Medical and Health Sciences Non-degree Award
Godfrey  Siu
ID: UNCST-2021-R005439
 The impact of COVID-19 on domestic care work in Uganda
REFNo: SS770ES

1. To determine the burden and patterns of domestic care work during the COVID-19 response phase.
2. To determine the barriers and facilitators of domestic work during the lockdown.
3. To examine the effects of COVID-19 on the social, economic and family relations.
 Uganda 2021-04-15 2024-04-15 Social Science and Humanities Non-degree Award
James Katungyi
ID:
The effect of daytime circadian thermal variability on the well-being of building occupants. A case study of office type building occupants in Kampala.
REFNo: SIR41ES

The research objective is to compare short and long-term impacts, of variable indoor thermal conditions (which mimic the outdoor variability) versus static thermal conditions, on the wellbeing of building occupants.
 Uganda 2021-04-13 2024-04-13 Engineering and Technology Degree Award
Susannah Mayhew Harding
ID:
Rapid Qualitative Research to support integrated environment, livelihoods and health programming in Uganda (“Supporting Integrated Programming”)
REFNo: HS1137ES

The research objectives are to:
1) Determine the environmental, livelihood and health challenges facing communities living in/near Rushebeya wetland;
2) Identify how, and through what structures and processes, people in these communities make decisions about and respond to identified challenges; and identify whether these responses have changed over time;
3) Examine whether there are differences in responses by age, sex or socio-economic background.
4) Identify messages and intervention activities to address the challenges felt by different groups in these communities.

 UK 2021-04-13 2024-04-13 Medical and Health Sciences Non-degree Award
Joseph Nkamwesiga
ID:
Epidemiology of Peste des Petits Ruminants (PPR) in Uganda
REFNo: A103ES

General Objective:
To determine national PPR risk profiles [low, medium and high], seroprevalence and incidence of different PPRV lineages, factors that influence PPRV transmission and hence develop a dynamic PPRV transmission model and the best control intervention(s) to limit PPRV transmission in selected livestock production systems in Uganda

The specific objectives of this study are to:
i. stratify Uganda districts into different PPR risk profiles [low, medium and high] by undertaking presence only ecological niche (MaxEnt) modeling of the past PPR outbreaks, small ruminant movements and vaccination coverage data sets
ii. estimate seroprevalence of PPRV and epidemiological factors that influence PPRV transmission within and between different PPR risk profiles and small ruminant production systems
iii. estimate PPR incidence and PPRV lineages involved in different PPR outbreaks across different small ruminant production systems [or agro-ecological zones] in Uganda
iv. develop a PPRV transmission dynamic and eradication model for PPR in selected small ruminant production systems [agro-ecological zones] in Uganda using compartmentalized SEIR mathematical modeling approach

 Uganda 2021-04-13 2024-04-13 Agricultural Sciences Degree Award
Freddy Kitutu Eric
ID: UNCST-2020-R014751
 Strengthening Antimicrobial Stewardship, Consumption and Use in Uganda (SAMSU)
REFNo: HS1155ES

To conduct Antimicrobial Consumption and Use by ATC/DDD Methodology and the WHO AWaRE classification Antimicrobials intended for use in Humans for the Years 2017, 2018, 2019 and 2020 using Medicine Imports and Local Manufacture Data in Uganda (SCACUS)To examine health facility bottlenecks and determinants of antimicrobial use that affect antibiotic stewardship practices at outpatient departments with the aim of strengthening healthcare professionals’ AMS capability in Eastern Uganda (SAMSEU)
Uganda 2021-04-13 2024-04-13 Medical and Health Sciences Non-degree Award
Stavia Turyahabwe Stavia
ID: UNCST-2022-R011373
 From Directly-Observed Therapy (DOT) to Video Observed Therapy (VOT): A study on the use of evidence based Digital Adherence Technologies (DAT) for improving TB Treatment outcomes
REFNo: HS1183ES

a. Active Case Finding Strategy: To study the impact of increase in case finding of drugs susceptible case in the selected 2 TB units of Kabarole and Mbarara, where the component will be tested.
b. Active Patient Compliance Toolkits: To test the efficacy of patient led adherence using mobile based Video Observed Therapy approach in improving the TB adherence rate and overall improvement in TB treatment outcomes;
c. Active Community-Led Supervision: To test the improvement in TB treatment outcomes like TB Success Rates, Cure rates and Adherence rates in the community let supervision model;
d. Active Ground Building Activities; To assess the change in knowledge, attitude and practice (KAP) level of TB patients; their family members and the community around TB and related issues.

Uganda 2021-04-13 2024-04-13 Medical and Health Sciences Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 SITUATIONAL ANALYSIS OF EXISTING CAPACITY AND RESOURCES AT MEAKERERE UNIVERSITY TO SUPPORT A RESEARCH TRAINING PROGRAM FOCUSING ON NON-COMMUNICABLE DIEASES AND AGEING AMONG PEOPLE LIVING WITH HIV/AIDS
REFNo: HS1252ES

General Objective
To describe existing research capacity, training and resources within the MakCHS that can be leveraged to design a successful NCD-HIV-Ageing training program at MakCHS
Specific Objectives
To describe existing NCD, HIV and ageing research at Makerere University and collaborating institutions within MakCHS and Mulago Hospital complex.
To define the existing NCD, HIV and ageing training activities at Makerere University and collaborating institutions within MakCHS and Mulago Hospital complex.
To outline the existing resources to support research and training on NCDs, HIV and ageing at Makerere University and other collaborating institutions within MakCHS and Mulago Hospital complex.
To define a pool of potential trainees that could be recruited for research training on NCDs, HIV and ageing at Makerere University and collaborating institutions within MakCHS and Mulago Hospital complex

 Uganda 2021-04-13 2024-04-13 Medical and Health Sciences Non-degree Award
Barbara Balikuddembe  Ndagire Balikuddembe
ID:
Dental Practitioners’ Knowledge, Attitudes, and Practices Regarding Caries Risk Assessment in the Management of Dental Caries in Uganda: A Cross Sectional Study
REFNo: HS1275ES

i. To determine the knowledge of dental practitioners regarding caries risk assessment in the management of dental caries in Kampala metropolitan. ii. To determine the attitudes of dental practitioners regarding caries risk assessment in the management of dental caries in Kampala metropolitan. iii. To determine the practices of dental practitioners regarding caries risk assessment in the management of dental caries in Kampala metropolitan. iv. To explore the training needs of CRA among trainers of dental practitioners in Kampala metropolitan.
Uganda 2021-04-13 2024-04-13 Medical and Health Sciences Degree Award
Victor Musiime
ID: UNCST-2021-R013794
 A randomized Trial to investigate strategies to reduce mortality among HIV-infected and HIV-exposed children admitted with severe acute malnutrition in Mulago Hospital, Kampala, Uganda
REFNo: HS1277ES

Primary objective
1. To investigate whether empirical use of an antibiotic with greater antimicrobial sensitivity (ceftriaxone) than standard of care (ampicillin plus gentamicin) will reduce mortality among 300 HIV-infected and HEU children admitted with severe acute malnutrition at Mwanamugimu Nutrition Unit, Mulago Hospital in a randomised controlled trial.

Secondary objectives
2. To compare the length of hospitalization, weight-for-height, weight-for-age and height-for-age z-scores between ceftriaxone versus standard of care (ampicillin and gentamicin) treatment arms.
3. To ascertain the frequency of different bloodstream bacterial pathogens and their antimicrobial sensitivities among HIV-infected and HEU children admitted with severe acute malnutrition at Mwanamugimu Nutrition Unit, Mulago Hospital participating in the randomised trial.
4. To ascertain the prevalence of, and factors associated with, HIV-infection among children admitted with severe acute malnutrition at Mwanamugimu Nutrition Unit, Mulago Hospital in light of improved PMTCT approaches in a cross-sectional evaluation at admission, among 280 children.
5. To evaluate the pharmacokinetic (PK) parameters of LPV/r among severely malnourished HIV infected children using sparse PK samples. The PK parameter values obtained will then be used in pharmacokinetic-pharmacodynamic (PK-PD) models to determine a possible optimal dose of LPV/r among severely malnourished children, which could then subsequently be evaluated in a clinical trial.

Uganda 2021-04-13 2024-04-13 Medical and Health Sciences Non-degree Award
Freddy Kitutu Eric
ID: UNCST-2020-R014751
 Exploring access to health care and medicines during COVID-19 in Mukono and Luwero districts: critical challenges and feasible policy options for the medicines retail sector
REFNo: HS1302ES

To describe the practical, policy and political barriers to including pharmacies, drug shops and private clinics in the response to COVID-19 and the means to overcome them.,. To describe how national actors and district officials would like to involve the medicines retail sector in their pandemic planning and action for COVID-19. ,To explore how the medicines retail sector in Uganda could be involved in response to COVID-19 and future outbreaks,To document the impact of the COVID-19 pandemic and public health response on the ability of women and the parents of young children in Uganda to access medicines,To document the effect of the government response to COVID-19 on supply of healthcare services/ care provision by drug shops, pharmacies and private clinics in Uganda,To describe how policy can be adapted to ensure continuity of access to essential medicines and support the involvement of the retail sector in COVID-19 activities during this and future outbreaks,To understand how the public health response to COVID-19 is shaping the supply of and access to treatment in the medicines retail sector in Uganda;,
 Uganda 2021-04-13 2024-04-13 Medical and Health Sciences Non-degree Award
Irene Mutuku M.
ID:
KNOWLEDGE, ATTITUDES AND PRACTICES TOWARDS COVID-19 PREVENTION MEASURES AMONG COMMUNITIES AT SELECTED GAZETTED INTERNATIONAL ENTRY-POINTS OF KIGEZI SUB-REGION, UGANDA
REFNo: SS660ES

General objective

To assess the knowledge, attitudes and practices towards COVID-19 prevention measures in communities living at gazetted international entry points of the Kigezi sub-region in Uganda.



Specific objectives
i. To establish the knowledge of the community members in selected gazette international entry points in the Kigezi region regarding measures instituted to stop the spread of COVID-19 in Uganda.

ii. To assess the attitudes of the community members in selected gazetted international entry points in the Kigezi region towards measures instituted to stop the spread of COVID- 19 in Uganda.

iii. To investigate the practices of community members in selected gazetted international entry points in the Kigezi region on measures instituted to stop the spread of COVID- 19 in Uganda.

 Kenya 2021-04-09 2024-04-09 Social Science and Humanities Non-degree Award
NEEMA NAKYANJO -
ID:
Fishing and inland communities – understanding transmission linkages and networks
REFNo: SS698ES

a) To understand the socio-structural context of migration of high risk persons/key populations to and from high HIV prevalence Lake Victoria fishing communities and other geographic areas with high HIV-prevalence
b) To use molecular, social and epidemiological data to identify and elucidate the factors/associations of transmission linkages/networks within key and general population cohorts/groups.
c) To increase our understanding of HIV prevention and care utilization of high risk persons/key populations moving to and from places with high rates of HIV infection
 Uganda 2021-04-09 2024-04-09 Social Science and Humanities Non-degree Award
JULIET MWANGA-AMUMPAIRE
ID: UNCST-2022-R009420
 Impact of malnutrition on pharmacokinetic of rifampicin, isoniazid, pyrazinamide and ethambutol in TB-HIV co-infected children
REFNo: HS1217ES

Primary Objective
To assess the effect of Severe Acute Malnutrition (SAM) on plasma concentration of rifampicin, isoniazid, pyrazinamide, and ethambutol in children with TB.

Secondary Objectives
1. To assess the effect of HIV-infection and antiretroviral treatment on plasma concentration of rifampicin, isoniazid, pyrazinamide, and ethambutol in children with TB and Severe Acute Malnutrition (SAM)
2. To assess whether new WHO-based dosages will achieve rifampicin, isoniazid, pyrazinamide, and ethambutol drug concentrations above the target therapeutic concentrations in HIV-TB co-infected children with and without SAM
3. To assess the effect of nutritional parameters, HIV-infection, antiretroviral treatment, and other factors (age, liver enzymes, NAT2 status) on PK parameters of rifampicin, isoniazid, pyrazinamide, and ethambutol in HIV-infected children with TB
4. To build a PK/PD relationship between drug concentrations and TB treatment outcomes
5. To assess rifampicin protein binding in relation with malnutrition and albuminemia
6. To derive an optimal dosing algorithm for rifampicin, isoniazid, pyrazinamide, and ethambutol that will adequately provide optimal exposures to malnourished and HIV infected children

 Uganda 2021-04-09 2024-04-09 Medical and Health Sciences Non-degree Award
Eva  Laker Odongpiny Agnes
ID: UNCST-2024-R004807
 A Toll-Free Call Intervention to Improve Adverse Events Reporting in Patients On Dolutegravir in Three Health Centers in Kampala, Uganda and a Prospective Cohort Study to Describe Adverse Events to Dolutegravir at the Infectious Diseases Institute (DOLUPHARM)
REFNo: HS1263ES

A) Primary objective (Objective 1)
To determine whether a toll-free phone system for reporting of adverse events by clinicians and patients improves adverse event reporting compared to standard reporting methods using paper based or online forms by clinicians in three health centers initiating/switching patients to DTG between November 2020 and October 2021.

B) Secondary objective (Objective 2)
To determine level of uptake and the experiences of clinicians and patients with using a toll-free phone system for reporting adverse events compared to standard reporting methods using paper based or online forms in three health centers initiating/switching patients to DTG between November 2020 and October 2021

Prospective Cohort Study
A) Primary objective (Objective 3)
To describe the incidence and factors associated with occurrence of different adverse events among patients being switched/initiated on a DTG-based regimen at the IDI.

B) Secondary objective (Objective 4)
To determine whether occurrence of adverse events affects adherence to medications among patients being switched/initiated on a DTG-based regimen at the

Uganda 2021-04-09 2024-04-09 Medical and Health Sciences Non-degree Award
Miriam Nakalembe
ID: UNCST-2021-R014040
 NEW APPROACHES FOR THE EARLY DETECTION OF CERVICAL NEOPLASIA
REFNo: HS1161ES

1. Determine acceptability and accuracy of a low-cost smartphone confocal micro-endoscope imaging technique for the diagnosis of CIN 2+. Confocal images will be compared against gold-standard histopathology to obtain preliminary diagnostic performance characteristics.
2. Compare various cervico-vaginal fluid (CVF) biomarkers to gold-standard histopathology for the diagnosis of CIN 2+. Qualitative and quantitative levels of biomarkers will be compared against gold-standard histopathology to obtain diagnostic performance characteristics.


Uganda 2021-04-08 2024-04-08 Medical and Health Sciences Non-degree Award
Susan Tino
ID:
Scale-Up and Capacity Building in Behavioral Science to Improve the Uptake of Family Planning and Reproductive Health Services (SupCap)
REFNo: HS1196ES

1. To test if the BSci Package can lead to an increased uptake of modern contraceptive methods improvements in gender norms, an increase in knowledge of contraceptive methods, birth spacing, and childrearing among postpartum women.

2. To find out how we effectively and efficiently replicate and scale up the BSci Package across Eastern Uganda and elsewhere.

 Uganda 2021-04-08 2024-04-08 Medical and Health Sciences Non-degree Award
Kamya Moses
ID: UNCST-2020-R014203
 A Multisectoral Strategy to Address Persistent Drivers of the HIV Epidemic in East Africa (SAPPHIRE)
REFNo: HS1239ES

Overall Objective: Our overall objective is to determine to reduce HIV incidence and to improve community health with multi-sector, scalable interventions.

Primary Objective: Reduce HIV incidence using innovative strategies for HIV prevention and treatment to simultaneously reach “persistent driver” populations.

Secondary Objectives:
1. Evaluate and optimize individual intervention component effects, alone (Phase A) and in combination (Phase B), versus control conditions on prevention coverage and HIV viral suppression
2. Assess the effect of the intervention package on other health outcomes (all-cause mortality, tuberculosis, hypertension linkage and control, heavy alcohol use and mother-to-child HIV transmission) in Phase B
3. Evaluate behavioral and other mechanistic pathways for intervention effects on proximal mediators of HIV incidence in Phase B
4. Assess the reach, effectiveness, patient and provider adoption, and fidelity and the maintenance of intervention components in Phase B
5. Use final study data to inform a strategic and sustainable investment model that maximally reduces HIV incidence and improves community health for the combination interventions tested in Phase B

 Uganda 2021-04-08 2024-04-08 Medical and Health Sciences Non-degree Award
CARL CHRISTIAN STECKER CHRISTIAN
ID:
Caregiver-Assisted Oral Fluid-based HIV Screening in Children: Estimation of Acceptability, Feasibility and Effectiveness Linked to Index Testing Services in Uganda.
REFNo: HS1258ES

The purpose of this study is to evaluate the acceptability, feasibility and effectiveness of a caregiver-assisted oral fluid based HIV test to screen children for HIV. The results of this study are intended to support expanded access to HIV testing and treatment services for children, and to ensure that all newly diagnosed children are linked to clinical care.

The primary objectives of this study are to:
1. Estimate the acceptability of implementing caregiver-assisted oral fluid-based HIV screening for children as part of index testing services for HIV-positive adults.
2. Estimate the feasibility of implementing caregiver-assisted oral fluid-based HIV screening for children as part of index testing services for HIV-positive adults.
3. Estimate the effectiveness of caregiver-assisted oral fluid-based HIV screening on testing yield, return to clinic, and linkage to ART for newly identified CLHIV.

The secondary objective of the study is to:
Estimate the cost of caregiver-assisted oral fluid-based HIV screening compared to the standard costs of the existing referral to testing program, from the perspective of the health care provider.

 USA 2021-04-08 2024-04-08 Medical and Health Sciences Non-degree Award
Leah Pauline
ID:
The Paradox of Being an Adolescent Girl in Uganda During a Global Pandemic
REFNo: SS765ES

My research aims to answer the following
research question and sub-questions:
How do adolescent girls in Uganda navigate the liminal period of COVID-19 when their
educational aspirations of empowerment are put on hold and they face exacerbating
pressures to abide by gender roles/expectations?
Sub-questions:
1- How do high school drop-outs in Uganda differ before and after the onset of the COVID-19 pandemic?
2- What factors influence adolescent girls’ reproductive health and
whether or not they return to school?
3- How do adolescent girls’ future aspirations play a role in their
continuation of schooling?
4- How do adolescent girls interpret peer drop-outs as they navigate their
own decision to continue their education or drop-out?
 USA 2021-04-08 2024-04-08 Social Science and Humanities Degree Award
Matthew Cooper
ID: UNCST-2021-R013904
 Legacy effects of land-use on tropical soils as constraints on the restoration success and service provision of tropical forests in Uganda
REFNo: NS157ES

The research subject of this project will be the evaluation of soil fertility, soil degradation, C sequestration in both soils and plants, and biodiversity along
tropical secondary forest successions in Western Uganda in three work
packages.
 UK 2021-04-06 2024-04-06 Natural Sciences Degree Award
FRANCIS KIBIRIGE
ID:
Do Legislatures Enhance Democracy in Africa, Uganda Chapter
REFNo: SS774ES

DLEDA Project seeks to understand how parliaments in (selected) African countries fulfill the core functions of parliament. This knowledge will enable DLEDA to answer three major questions, including:

Question 1: Which policy decisions are made in the national assembly?

Question 2: Who are the Members of Parliament (i.e. caliber) and how do they interact with each other?

Question 3: How do MPs represent their constituents and what are the existing mechanisms of political accountability?

 Uganda 2021-04-06 2024-04-06 Social Science and Humanities Non-degree Award
Allan Lugaajju
ID:
B-CELLS AND HUMORAL FACTORS MEDIATING MALARIA IMMUNITY IN CHILDREN AND ADULTS
REFNo: HS1267ES

1.To quantify reactive Plasmodium falciparum specific B cell subsets against parasite antigens in children and adults.

2.To functionally characterize anti-Plasmodium falciparum B cell subset downstream responses in children and adults

3.To compare the reactivity and proportions of Plasmodium falciparum specific B cell subsets in children and adults

Uganda 2021-04-06 2024-04-06 Medical and Health Sciences Non-degree Award
David Lwanga
ID:
CONFLICTING PRESSURES FOR CHANGE AND INSTITUTIONAL LEGITIMACY IN KAMPALA CAPITAL CITY AUTHORITY, UGANDA.
REFNo: SS780ES

5. To find out the extent to which quantitative results on institution legitimacy of KCCA supports the initial qualitative results.,4. To examine the extent to which the legitimacy of KCCA is a result of harmonizing conflicting pressures for change. ,3. To find out how KCCA dealt with pressures resisting change during the transformation period.,2. To establish the strategic responses that KCCA adopted to attain institutional legitimacy.,1. To establish what institutional pressures influenced the transformation of KCC to KCCA.,To understand how Kampala Capital City Authority attained institutional legitimacy amidst conflicting pressures for change, that is how change initiatives can be positively embraced, hence creating self-reinforcing sequences for institutional legitimacy. ,
 Uganda 2021-04-06 2024-04-06 Social Science and Humanities Degree Award
Borja Perez-Viana
ID:
Go for It while You Can: On Time Discounting in High-Risk Environments
REFNo: SS448ES

The poor populations of developing countries are extremely exposed to the vagaries of chance, with agricultural output and livelihoods dependent on highly variable weather patterns. Against this background, it is important to better understand how people in developing countries make decisions involving risk and time trade-offs. Our understanding of these decisions is still hampered by a number of issues. For one, decisions under risk and over time have long been treated separately, whereas in reality, they are closely linked. Investigations in developing countries have often focused on exceedingly simple preference measures that are presented in a theoretical vacuum. Likewise, the identification of causal determinants of preferences remains elusive. We propose to overcome these limitations by combining the modelling of preferences and their determinants with bespoke tools to measure preferences and beliefs. We further propose to combine the model-driven measurements with randomised controlled trials (RCTs) varying theoretically identified determinants of preferences to enable us to draw clear causal inferences. Combining such RCTs with a longitudinal design will further allow us to investigate interactions between the randomly allocated interventions and naturally occurring uncertainty. The study will be carried out in collaboration with the Field Lab, a non-for-profit research organisation, based in Mbale.

We divide our proposal into five work packages:

1. Modelling and measuring future uncertainty: The future is inherently uncertain. It is even more so in developing countries. This uncertainty may indeed drive both high levels of risk taking in the present and extreme time discounting. In this first work package, we aim to model this issue explicitly, and to measure the underlying quantities, with particular attention to future uncertainty.

2. Future probabilities are ambiguous: This work package extends the insights obtained in the first work package to explicitly take the uncertainty surrounding future probability estimates into account. The modelling and experimental measurements are further complemented by a randomised variation of the institution delivering the future payouts.

3. Gain, loss, and mixed inter-temporal prospects: In work package three, we propose to extend the theoretical and measurement apparatus deployed in the first two work packages to a full inter-temporal prospect theory model. This is important to model real decisions, which often involve trading off immediate expenditures against uncertain future outcomes.

4. Background risk and behaviour: Starting from a model of the influence of background risk on decisions under risk and over time, we aim to provide crop insurance to randomly selected subsistence farmers in order to shelter them from background risk. This ought to allow us to draw causal inferences on the effect of background risk on preferences and behaviour.

5. Training, aspirations, and locus of control: Taking risks and investing into the future may be mediated by psychological mechanisms such as aspiration levels or locus of control (beliefs on whether one can control one’s destiny). We aim to augment an existing training intervention by motivational elements aimed directly at shifting these psychological mechanisms, to try and nudge preferences and behaviour in desirable directions.
 Spain 2021-03-31 2024-03-31 Social Science and Humanities Non-degree Award
Susan  Nabadda
ID: UNCST-2020-R014331
 Surveillance and Epidemiology of Antimicrobial Resistance Programme (Pilot)
REFNo: HS1268ES

Primary

To evaluate AMR incidence through the establishment of a surveillance platform in LMICs based on Pfizer’s Antimicrobial Leadership Testing and Surveillance (ATLAS) core methodology, while facilitating the expansion of surveillance capacity in participating countries.
Secondary.
To strengthen the quality of identification and antimicrobial susceptibility testing of major bacterial pathogens by the participating laboratories through retesting at a central reference laboratory;
ï‚· To estimate and track the prevalence of resistance phenotypes of major public health importance notably extended spectrum cephalosporin resistance, Carbapenem resistance and MRSA;
ï‚· To generate WGS data that shall be used for epidemiological typing and determining mechanisms of resistance of major resistance phenotypes in participating countries.
 Uganda 2021-03-31 2024-03-31 Medical and Health Sciences Non-degree Award
Nazarius Tumwesigye Mbona
ID: UNCST-2019-R000664
 A Midline Evaluation for a 5 Year Family Planning Implementation Program: The RISE Project in Uganda
REFNo: HS1296ES

1. Describe the socio-demographic characteristics of men and women of reproductive age living in the seven RISE regions at midway of implementation of RISE programme
2. Assess the program progress from baseline to midline on each of the following program intervention areas
a. men and women’s knowledge of FP services and methods in the project areas
b. men and women’s attitudes towards FP in the project areas
c. FP practices amongst men and women of reproductive age in the project areas
d. the intention to use FP services in future among men and women of reproductive age in the project areas
e. Ability and willingness to pay for FP services among men and women of reproductive age group in the project areas
f. level of exposure to SBCC messages on FP amongst men and women of reproductive age in the project areas
g. status of FP user segments for both men and women of reproductive age in the project areas in terms of Knowledge, attitude, practices, intent to use, exposure
3. Assess the effect of COVID-19 on access of family planning services among men and women of reproductive age living in the seven RISE regions at midway of implementation of RISE programme

 Uganda 2021-03-31 2024-03-31 Medical and Health Sciences Non-degree Award
Moses Ocan
ID:
Predictors of local emergence and spread of Artemisinin resistance among Ugandan Plasmodium falciparum parasites
REFNo: HS1169ES

(i) To assess the extent of adherence to national malaria treatment guidelines/policy in malaria treatment in private hospitals, private pharmacies and public hospitals in low and high malaria transmission settings in Uganda
(ii) To determine the prevalence of Pfkelch13 gene mutations among P. falciparum parasites in low and high malaria transmission settings in Uganda
(iii) To determine the prevalence of fd (ferredoxin), arps10 (apicomplast ribosomal protein S10) , mdr-2 (multi-drug resistance protein -2) and crt (chloroquine resistance protein) mutations among Plasmodium falciparum parasites in low and high malaria transmission settings in Uganda

 Uganda 2021-03-26 2024-03-26 Medical and Health Sciences Non-degree Award
Pakoyo Kamba Fadhiru
ID:
Scaling up the Refugees and Host Community’s response towards COVID-19 in Northern Uganda
REFNo: SS755ES

1. To assess the refugee and host communities’ compliance with COVID-19 infection prevention and control measures such as social distancing, hand washing, hand sanitization, use of personal protective equipment, quarantine and notification of cross-border travellers and suspect cases to authorities. 2. To identify community-led initiatives towards COVID-19 infection prevention and control. 3. To build the capacity of refugee settlement and community leaders in COVID-19 infection prevention and control.
Uganda 2021-03-26 2024-03-26 Social Science and Humanities Non-degree Award
Shevin  Jacob Thomas
ID:
EVALUATION OF PHARMACOKINETICS, SAFETY AND FEASIBILITY FOR ADMINISTRATION OF TWO DOSES OF INTRAVENOUS VITAMIN C COMBINED WITH VITAMIN B1 FOR THE MANAGEMENT OF ADULT PATIENTS ADMITTED WITH SEPSIS TO KIRUDDU NATIONAL REFERRAL HOSPITAL Short Title: RANDOMISED EVALUATION OF A VITAMIN C BUNDLE FOR SEPSIS TREATMENT IN AFRICA (REVISTA-DOSE)
REFNo: HS1236ES

General objective: In the future REVISTA-RCT, we intend to evaluate the components of a metabolic bundle comprising vitamin C, vitamin B1, and corticosteroids in order to determine if a combined effect of the bundle has greater efficacy (than bundle components or placebo) in decreasing 28-day mortality due to sepsis in adult patients in SSA. In preparation for the RCT, we intend to utilize the REVISTA-DOSE study to answer key questions about optimal dosing and safety for intravenous vitamin C (in combination with vitamin B1) in patients hospitalized with adult sepsis in two Ugandan referral hospitals. Primary objectives: 1. Describe the dose-plasma concentration response from two different doses of intravenous vitamin C (in combination with vitamin B1) Secondary objectives: 1. Evaluate the safety and tolerability of intravenous vitamin C (in combination with vitamin B1) in adult medical patients with sepsis in Uganda 2. Assess the enrolment rates, adherence to protocol and feasibility of conducting an RCT in patients with sepsis within the ARCS cohort of patients Exploratory objectives: 1. Evaluate association of vitamin C and vitamin B1 levels on clinical parameters/markers, including those for: a. Disease severity: shock; lactate clearance; qSOFA score; ability to stand unaided b. Inflammation, infection: Procalcitonin c. Organ/metabolic function, including: renal function d. Adverse events: hemolysis; oxaluria e. Outcomes: re-hospitalization frequency; length of hospitalization; 6 or 7 and 28d morbidity and mortality
USA 2021-03-26 2024-03-26 Medical and Health Sciences Non-degree Award
Barbara Mukasa
ID:
Evaluating the Glycemic Effects of Dolutegravir (DTG) Among Patients Receiving Dolutegravir Based Regimens at Mildmay Uganda ART sites : A Prospective Cohort Study
REFNo: HS1273ES

1.To determine the incidence of hyperglycaemia among patients receiving DTG based regimen at Mildmay Uganda supported sites. 2.To determine the association between previous NRTI or NRTtI exposure and the incidence of hyperglycemia among patients on TLD.
3.Evaluate predictors of hyperglycaemia among patients on TLD. 4.Describe other adverse events reported by study participants during the study period.
Uganda 2021-03-26 2024-03-26 Medical and Health Sciences Non-degree Award
Agnes Kiragga
ID:
Community Pharmacies for Assessing STI Prevalence using Point of Care diagnostics study (COPHAS)
REFNo: HS1274ES

Aim 1: To estimate the prevalence of curable STIs and HIV among persons accessing health services at community pharmacies in Kampala and Wakiso Districts.

Aim 2: To determine the feasibility and uptake of pharmacy-based specimen collection and POC testing for curable STIs and HIV among persons seeking health care services at community pharmacies in Kampala and Wakiso Districts. Uptake will be measured among the three groups of persons i.e. Persons seeking EC (group 1), clients with STI symptoms (group 2) and persons without STI symptoms (group 3)
Secondary quantitative aims:
Aim 3: To determine treatment completion among persons diagnosed with an STI at the community pharmacies in Kampala and Wakiso Districts.

Aim 4: To determine linkage to care and ART initiation among newly diagnosed HIV positive persons at the community pharmacies in Kampala and Wakiso Districts.

Aim 5: To determine the baseline and 3-month knowledge about STI and STI treatment guidelines, and principles of antimicrobial stewardship of pharmacy staff. In addition, to assess the acceptability of POC STI diagnostics collocated with the pharmacy, to pharmacy owners and staff.

Qualitative aims
Aim 6: To assess the acceptability and client satisfaction of STI and HIV testing at community pharmacies in Kampala and Wakiso Districts.

Partner notification sub-study
Aim 7: To determine the effect of technology-supported partner notification and treatment initiation using Call for LifeTM technology among persons diagnosed with an STI or HIV at community pharmacies.


 Uganda 2021-03-26 2024-03-26 Medical and Health Sciences Non-degree Award
Moses Adriko
ID: UNCST-2019-R001787
 Information and Evidence Rapid Needs Assessment for COVID-19 in Uganda
REFNo: HS1285ES

A rapid needs assessment gives insights about the dissemination and utilisation of information and evidence related to the coronavirus (COVID-19) pandemic by individuals engaged at various levels of public health. The use of timely and accurate information about COVID-19 by public health workers will help to support the population in risk reduction through community education and the adoption of protective behaviours. As the outbreak progresses, it is important to understand: how health workers are getting their information (the sources); if the dissemination of official guidance is received, how it is perceived, and if it is followed; and the gaps in information and evidence at the subnational level; identify needs related to community and health facility COVID-19 information materials. Developing an understanding of and monitoring these issues will increase the use of timely and accurate information, and ultimately improve the dissemination of timely and accurate information to the population. The objectives of the project are as follows:
(1) To understand the different sources of information used by health workers in decision making on COVID-19.
(2) To identify the gaps in the dissemination of accurate information in the management of COVID-19 in Uganda.
(3) To improve the dissemination of timely and accurate information to the population about COVID-19 in Uganda.

 Uganda 2021-03-26 2024-03-26 Medical and Health Sciences Non-degree Award
Peter Olupot-Olupot
ID:
H-PRIME Hydroxyurea - Pragmatic Reduction In Mortality and Economic burden
REFNo: HS818ES

TRIAL OBJECTIVES
The primary objective of the trial is to identify pragmatic, effective, safe and acceptable interventions to reduce short and longer-term mortality and morbidity in children with SCD in sub-Saharan Africa. There are three hypotheses being tested

1. [Randomisation, R1] Daily oral hydroxyurea at a fixed weight-band based dose given with clinically driven (rather than routine scheduled) laboratory monitoring, without titrating doses to the MTD, will reduce all-cause mortality compared with placebo
2. [R2] Enhanced antimalarial prophylaxis will reduce malaria-associated hospitalisation vs standard of care (SOC) (open-label)
3. [R3] Enhanced antimicrobial prophylaxis will reduce all-cause hospitalisation vs SOC (open-label)

Secondary objectives include
 To determine the efficacy of the strategies above on other measures of morbidity
 To determine the safety and tolerability of the strategies above
 To identify the most cost-effective interventions to reduce mortality and morbidity, and assess their budget impact
 To investigate the cardiac safety of DHA-PQP in children with sickle cell disease
 To investigate the resistance patterns of malaria parasites acquired by children on different forms of malaria prophylaxis

 Uganda 2021-03-24 2024-03-24 Medical and Health Sciences Non-degree Award
Emmanuel Bizimungu
ID:
The role of incentives for adoption of climate-smart agricultural innovations: An experimental evaluation in Uganda
REFNo: SS502ES

The main objective of this study is to assess the effectiveness of the incentives for the adoption of Climate-smart Agricultural (CSA) innovations, and ensuing impacts on farming systems resilience and household welfare, and examine the effects of weather, market, and payment uncertainties on investments in CSA innovations.

Specifically, this research will:
1. Assess the effects of different bundles of ‘push’ and ‘pull’ incentives on adoption intensity of climate-smart agricultural practices and technologies;

2. Determine smallholders’ behavioral responses to shocks and examine the extent to which uncertainties regarding weather, market and, timing of payment influence smallholders’ decisions to invest in inputs with/without incentives;

3. Analyze the effects of CSA adoption for intra-household decision-making;

4. Assess the impacts of CSA practices and technologies on farming systems’ resilience, factor productivity, revenues, income and, nutrition.

 Uganda 2021-03-24 2024-03-24 Social Science and Humanities Degree Award
EVA NATUKUNDA
ID: UNCST-2020-R014330
 Safety of alternative second- line anti-retroviral drugs in HIV- infected children living in Uganda and Zimbabwe
REFNo: HS1071ES

1. To evaluate the renal and bone adverse events associated with TAF when compared to ABC or ZDV among HIV infected children on second line ART
2. To evaluate the effect of TAF on BMD and turnover markers compared with ZDV or ABC among HIV infected children on second line ART.

3. To evaluate the effect of ritonavir boosted Atazanavir (ATV/r), Darunavir (DRV/r), Lopinavir (LPV/r) and DTG based regimens on lipid profiles and body fat distribution.
4. To determine the prevalence and baseline characteristics associated with low BMD among children starting second- line ART in Uganda.
5. To determine the sensitivity, specificity and predictive values of the QUA compared with DXA scan in measuring BMD among HIV infected children on second line ART.


 Uganda 2021-03-24 2024-03-24 Medical and Health Sciences Degree Award
Adam Hewitt Smith
ID: UNCST-2019-R001658
 Family SuppleMented pAtient monitoRing afTEr suRgery (SMARTER) pilot trial
REFNo: HS944ES

To develop a training and support intervention, in accordance with the MRC complex intervention framework, to train family carers to perform and document basic vital signs, to supplement routine monitoring of patients by nursing staff, whilst they provide personal care to their relatives after surgery and to evaluate the effect of this intervention on frequency of documented vital signs for patients in the first three days after surgery in a stepped-wedge cluster trial.
To evaluate compliance with the trial intervention, and how this changes over the duration of the trial.
To evaluate the effect of the intervention on in-patient mortality, to inform the design of a subsequent international clinical trial across Africa
 UK 2021-03-23 2024-03-23 Medical and Health Sciences Degree Award
Robin NESBITT Clark
ID:
Impact of COVID-19 on HIV and TB patient care in Malawi and Uganda
REFNo: HS1218ES

To describe the impact of COVID-19 and the public health measures to control the spread of COVID-19, on HIV and TB patients and their care in the MSF projects in Chiradzulu, Malawi and Arua, Uganda, including patient perspectives and perceptions.
 Canada 2021-03-23 2024-03-23 Medical and Health Sciences Non-degree Award
Victoria Nankabirwa
ID: UNCST-2021-R011871
 Pilot Randomized Controlled trial: Preventing infant Malnutrition (PrIM)
REFNo: HS1226ES

Primary Objective
To determine the effect of early small volume supplementation (ESVS) on weight-for-age Z-scores (WAZ) at 30 days of age.
Secondary Objectives
1. To determine the effect of ESVS on WLZ at 30 days of age.
2. To determine the effect of ESVS on WAZ, WLZ, and LAZ through 6 months
of age.
3. To measure the effect of ESVS on breastfeeding duration through 6 months of
age.
4. To determine the effect of ESVS on intestinal microbiota at 30 days of age.
 Uganda 2021-03-23 2024-03-23 Medical and Health Sciences Non-degree Award
Catherine Barasa Asekenye
ID:
Development of community-led approaches to support sexual and reproductive health among survivors of trafficking in Uganda
REFNo: SS746ES

1. Define survivor-led SRH priorities
2. Identify gaps in addressing priorities as identified by survivors and local healthcare providers
3. Test the methodological suitability of two participatory approaches (Photovoice and participatory action research) as transformative methods
4. Bring together stakeholders working with communities of survivors, and based on objectives 1–3, develop a Phase II intervention that supports transformative participatory research approaches among communities of survivors and works with local healthcare providers to provide integrated SRH, as per the needs and expectations of survivors
Uganda 2021-03-23 2024-03-23 Social Science and Humanities Non-degree Award
Dennis Muhanguzi
ID: UNCST-2019-R001101
 Prevalence and Economic Importance of Key Endemic Livestock Diseases in Kaabong and Amudat Districts, Karamoja Region
REFNo: NS163ES

The specific objectives of this project will be to determine: -
i.Sero-prevalence of FMD, CBPP and CCPP in Amudat and Kaabong districts, Karamoja region
ii.Prevalence of Tick-borne hemoparasites [TBHs] in cattle populations from Amudat and Kaabong districts, Karamoja region
iii.Prevalence of helminths Species of Veterinary importance in Amudat and Kaabong districts, Karamoja region
iv.Estimates of the socioeconomic impact of FMD, CBPP and CCPP in Amudat and Kaabong districts, Karamoja region
v.Estimates of the socioeconomic impact of TBHs in Amudat and Kaabong districts, Karamoja region
vi.Estimates of the socioeconomic impact of different helminths Species of Veterinary importance in Amudat and Kaabong districts, Karamoja region
Uganda 2021-03-23 2024-03-23 Natural Sciences Non-degree Award
Andrew Mujugira
ID: UNCST-2019-R000871
 PrEP Persistence and Risk of HIV and Sexually Transmitted Infections among Transgender Men in Uganda
REFNo: HS990ES

Aim 1: Characterize HIV and STI prevalence and risk among trans men Aim 2: Evaluate PrEP uptake and persistence among HIV-negative trans men Aim 3: Explore sexual health experiences and risk behaviours of trans men in Uganda
Uganda 2021-03-22 2024-03-22 Medical and Health Sciences Non-degree Award
Justin Willis
ID:
Uganda’s past, Uganda futures: debates over government, equality and justice, 1979-80
REFNo: SS473ES

· The building of an interdisciplinary research team that demonstrates the relevance of study of the past through a co-produced programme of research and capacity-building;
· Providing a cohort of early-career Ugandan scholars with mentored experience in the techniques of researching the past through interdisciplinary methods, academic writing, and writing for non-academic audiences;
· Producing a published volume showcasing the work of the team;
· Publishing a project blog presenting key findings of the research to non-academic audienc-es
· Creating media outputs that widen the audience and impact of the research
· Presenting the research to civil society organizations, policy makers and a wider audience through a final mini-conference
· The development of one or more applications for further external funding that will enable the career progression of these researchers and the sustainability of the network

 UK 2021-03-19 2024-03-19 Social Science and Humanities Non-degree Award
Ponsiano Ocama
ID: UNCST-2019-R000440
 Obesogenic Impact of Dolutegravir-based Antiretroviral Therapy among HIV-Infected Ugandans
REFNo: HS1029ES

The primary aim is to rigorously investigate the obesogenic effects of DTG switches including: 1. Body composition changes, using body mass index (BMI) and anthropometrics and whole body DXA to measure lean and fat mass (including whole body, trunk, and limb). 2. Ectopic fat changes, emphasizing hepatic fat as measured noninvasively using the continuous attenuation parameter (CAP) measured in dB/m by FibroScan. 3. Cardiometabolic changes, through measurement of HOMA-IR, hemoglobin (Hb)A1c, and fasting lipid panel. We will also explore a major potential mechanism of INSTIrelated weight gain by measuring orexigenic (ghrelin, adiponectin) and anorexigenic (leptin, PYY) hormones, which have been implicated in the pathogenesis of antipsychotic related weight gain, as well as weight loss related to bariatric surgery
 Uganda 2021-03-18 2024-03-18 Medical and Health Sciences Non-degree Award
Aisa Muhamad
ID:
Rewards Management and Performance of Selected Secondary Schools in the Central Region of Uganda
REFNo: SS713ES

i) To establishthe rewards provided in theselected secondary schools in central region of Uganda.
ii) To examine the relationship between monetary rewards andthe performance of secondary schools in central region of Uganda.
iii) To examine therelationships ofnon-monetary tangible rewardsand the performance of secondary schools in central region of Uganda.
iv) To establish the relationships ofnon-monetary intangible rewards and the performance of secondary schools in central region of Uganda.
v) To examine the level of school performance in the selected secondary schools in central region of Uganda.

Uganda 2021-03-18 2024-03-18 Social Science and Humanities Degree Award
Andrew Mujugira
ID: UNCST-2019-R000871
 Formative research to guide PrEP delivery within harm reduction services for people who use drugs in Uganda
REFNo: HS1202ES

Aim 1. To explore experiences with and willingness for PrEP for PWUD:
a.among PWUD in Kampala, Uganda, explore willingness to use PrEP.
b.among providers of oral PrEP and services for PWUD in Kampala, Uganda, explore willingness to prescribe PrEP

Aim 2. To explore experiences during the COVID-19 pandemic with regards to:
a.accessing services by PWUD
b.providing services for mental health, substance use, HIV prevention, and social services by harm reduction providers
 Uganda 2021-03-18 2024-03-18 Medical and Health Sciences Non-degree Award
ABDUL WALUSANSA
ID:
Drug Resistant Bacterial Contamination and Efficacy of Selected Herbal Medicines Sold in Kampala, Uganda
REFNo: HS1278ES

The broader aim of this study is examining the prevalence, antibiotic susceptibility, resistance genes in bacterial contaminants, and the antibacterial efficacy of selected herbal medicines sold in Kampala, in order to contribute to the mitigation of AMR.,To determine the antibacterial efficacy of some herbal medicines against selected drug-resistant bacterial isolates in Kampala. ,To examine the risk factors for bacterial contamination of herbal medicines sold in Kampala, Uganda ,To determine antibiotic resistance genes in multi-drug resistant bacteria isolated from herbal medicines sold in Kampala.,To determine the prevalence and antibiotic susceptibility of pathogenic bacterial contaminants such as, Klebsiella pneumoniae, Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, Salmonella spp, Shigella spp, and Clostridium perfringens in herbal medicines sold in Kampala.,
 Uganda 2021-03-18 2024-03-18 Medical and Health Sciences Degree Award
Francis Kombe Kazungu
ID:
Implications of fieldworkers’ institutional support systems for research integrity practices in Africa
REFNo: SS760ES

i) Describe and analyse the existing literature, including concepts and theories related to fieldworkers’ institutional support systems and policies
ii) Identify and describe existing fieldworkers' institutional support systems at the participating research institutions.
iii) Critically evaluate how existing fieldworkers' institutional support systems and policies shape fieldworkers ethical and research integrity practices.
iv) Develop a best practice model and make recommendations to the participating institutions on fieldworkers’ institutional support systems

 Kenya 2021-03-18 2024-03-18 Social Science and Humanities Degree Award
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"A prosperous Science and Technology Led Ugandan Society."

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