Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
Search By Approval Date:
Clear Filter Total: 5,299
Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Hesbon  Owilla Hansen
ID:
QUANTITATIVE AND QUALITATIVE STUDY ON INNOVATION FOR MEDIA VIABILITY IN EAST AFRICA
REFNo: SS417ES

1. To bolster the viability of media outlets
2. To galvanize media innovation in East Africa, with a focus not just on creative content but on new and sustainable business models for the future.
Kenya 2020-09-08 2023-09-08 Social Science and Humanities Non-degree Award
Fatuma  Namusoke University
ID:
Barriers, knowledge and antimalarial antibodies in relation to Intermittent Preventive Treatment in pregnancy use in Kawempe National Referral Hospital
REFNo: HS620ES

1. Explore the barriers of IPTp implementation in Kawempe National Referral Hospital
2. To describe the knowledge and perceptions of IPTp among mothers Kawempe National Referral Hospital
3. To determine the association between quantity and quality of antimalarial antibodies in puerperium and use of IPTp during pregnancy

Uganda 2020-09-04 2023-09-04 Medical and Health Sciences Non-degree Award
Mark Jordans
ID: UNCST-2020-R014861
Increasing the efficiency of an education programme to facilitate rapid adoption and sustainable scale-up.
REFNo: SS451ES

Aim: To increase the efficiency and scalability of the Can’t Wait to Learn (CWTL) programme, through increasing access, attendance, retention and facilitating programme adoption.

The specific objectives of the present research studies are:
1) To develop and test a caregiver engagement intervention to increase children’s equitable access to, attendance of and retention in CWTL;
2) To assess and optimise the CWTL implementation team model to facilitate rapid adoption and scale up of the programme;
3) To evaluate the value for money of CWTL and identify drivers and drainers of value for money.
Netherlands 2020-09-04 2023-09-04 Social Science and Humanities Non-degree Award
Pauline Byakika-Kibwika
ID: UNCST-2019-R001206
Optimizing malaria treatment for HIV-malaria co-infected individuals by addressing drug interactions between Artemether-Lumefantrine and Efavirenz.; a randomized trial
REFNo: HS820ES

General Objective: To utilize innovative interventions to overcome drug interactions between artemether-lumefantrine and efavirenz to guide malaria treatment for individuals co-infected with HIV and malaria.
Specific objectives:
1. To determine the safety and Pharmacokinetics of the double dose artemether-lumefantrine when administered with efavirenz based ART among healthy volunteers (malaria negative and HIV negative individuals).
2. To determine the safety and Pharmacokinetics of the 5-day course of artemether-lumefantrine when administered with efavirenz based ART among healthy volunteers (malaria negative and HIV negative individuals).
3. To determine the safety, pharmacokinetics and malaria treatment outcome of a standard dose of artemether-lumefantrine compared to double of the standard dose for weight and a 5-day course of artemether-lumefantrine for treatment of uncomplicated malaria among HIV-Malaria co-infected individuals receiving efavirenz-based ART.
4. To determine the safety and Pharmacokinetics of artemether-lumefantrine when administered with Dolutegravir based ART among HIV-malaria co-infected individuals

Uganda 2020-09-04 2023-09-04 Medical and Health Sciences Non-degree Award
Grace Kagoro
ID: UNCST-2021-R013951
Digital citizen science for community-based resilient environmental management
REFNo: NS126ES

1. Enhance a network of hazard reporters and participating communities across the targeted districts.
2. Strengthen the academic capacities (PhD & MSc) of the two partner institutions hence development of
evidence based research on disaster risk reduction and sustainable rural livelihood strategies.
3. Generate knowledge factors controlling the spatial- temporal distribution of environmental risks and land
degradation.
4. Contribute to the establishment of a platform for multi-actor dialogue of environmental resilience.
5. Contribute towards the interpretation and policy recommendations to the policy makers basing on the
collected data about environmental natural hazards, resilience and mitigation measures.
6. Increase community awareness about effect of human activities on accelerating environmental natural
hazards, their resilience and mitigation measures.
7. Develop and test new methods to initiate multi-lateral interactions between rural communities, district
authorities and scientists and favor the implementation of resilient livelihood practices.
8. Enhance the knowledge and skills of the Geo-observers as environmental facilitators to be able to serve as
interface between the communities and the scientists.

Uganda 2020-09-04 2023-09-04 Natural Sciences Degree Award
Laban Musinguzi Kashaija
ID: UNCST-2020-R014407
Baseline Survey on HIV Prevention Programme among Key Populations in Uganda
REFNo: SS508ES

The baseline study shall establish knowledge on:
• KPs ability to protect themselves against HIV
• The level of access to KP friendly health services
• The level of structural barriers to HIV treatment and prevention for KPs
• The level of organizational capacity of programme partners & cross-country programme interventions.

Uganda 2020-09-04 2023-09-04 Social Science and Humanities Non-degree Award
Edgar Tusingwire Bagarukayo Bagarukayo
ID:
Analysis of Capacity development and Participation of Local companies in the Oil and gas industry: A case of Ugandan Companies
REFNo: SS515ES

-To examine the approaches and mechanisms used by Ugandan Companies’ for capacity development;
- To examine the roles of various capacity building actors and how they facilitate or inhibit capacity development;
- To analyze how Ugandan Companies’ have deployed the capacity acquired to participate in the oil and gas industry in Uganda.

Uganda 2020-09-04 2023-09-04 Social Science and Humanities Degree Award
PAUL ISABIRYE
ID:
Determinants of Family Planning Services uptake among first time parents in Uganda
REFNo: HS868ES

1. To determine the level of uptake of family planning services among first time parents.
2. To identify the individual factors that determine family planning services uptake among the first time parents.
3. To assess the contextual drivers of family planning services uptake among the first time parents.
4. To assess family planning services uptake challenges among first time parents.

Uganda 2020-09-02 2023-09-02 Medical and Health Sciences Non-degree Award
PAUL ISABIRYE
ID:
An Analysis of the drivers of Antenatal Care leaks along the ANC cascade in Uganda: A case study of RHITES Implementing Mechanisms
REFNo: HS876ES

a. To identify the causes of dropout of mothers from antenatal care service delivery in Uganda.
i. To identify the individual factors that drive drop out of mothers from ANC services.
ii. To identify socio-cultural factors that influence mothers to drop out of antenatal care along the ANC cascade.
iii. To examine the institutional factors that drive loss of clients in ANC care across the ANC cascade.
b. To determine the level of completion of four ANC visits and more than four ANC visits among mothers attending antenatal care
c. To identify the approaches used by the different health institutions to minimize loss of mothers from antenatal care across the ANC cascade.

Uganda 2020-09-02 2023-09-02 Medical and Health Sciences Non-degree Award
Rita Nakalega
ID: UNCST-2019-R000599
PEER-DELIVERED HIV SELF-TESTING AND PrEP FOR YOUNG WOMEN IN UGANDA
REFNo: HS845ES

1. To assess the feasibility and acceptability of using peer-delivered HIVST and oral PrEP to young women in Uganda.
2. To explore how peer-delivery of HIVST and PrEP influences PrEP persistence among young wome
Uganda 2020-08-28 2023-08-28 Medical and Health Sciences Degree Award
Diana Nabbumba Erinah
ID:
Exploring the systemic nature of social care provision and expectations for older people in rural Uganda: A transformative qualitative study
REFNo: HS322ES

This study aims to investigate the current state of social care for older people in rural areas of Uganda. It will establish who is responsible for aged care in rural Uganda, the challenges and gaps in the current social care system and provide recommendations to address these gaps and challenges. The study is significant because it will contribute to the body of knowledge of social care in rural areas of developing countries. More specifically, this research will increase awareness of the plight of older people in seeking social care, and allow for recommendations to be made to key relevant stakeholders
Uganda 2020-08-26 2023-08-26 Medical and Health Sciences Degree Award
Adeodata Rukyalekere Kekitiinwa Kekitiinwa
ID: UNCST-2019-R000799
Project Evaluation Protocol for the ACE-FORT Project: Entitled; “Accelerating Epidemic Control in Fort Portal Region in the Republic of Uganda under the President’s Emergency Plan for AIDS Relief (PEPFAR)”
REFNo: HS740ES

i) To determine the extent to which the project; a) Increases the proportion of PLHIV with known HIV status by 2020, b) Increases the proportion of people diagnosed with HIV accessing ART by 2020, c) Increases proportion of people receiving ART who are virally suppressed by 2020, d) Achieves coverage of high impact combination prevention interventions in scale-up districts by 2020, e) Provides Healthy, Safe, Stable, Schooled, and case management services along the Continuum of Response to eligible OVC and their families and graduate families out of Vulnerability by 2023, f) Strengthens regional and district governance and systems for sustained epidemic control by 2023.
ii) To Assess the relevance of; a) Prevention services in reducing the incidence of HIV in Fort portal region, b)Treatment and care services in reducing HIV related morbidity and mortality, c) OVC services in reducing the vulnerability of families with HIV.
iii) To assess the potential for sustainability of project components, results achieved and other efforts aimed at achieving HIV epidemic control in Fort Portal region.
iv) To assess the cost of; a) identifying new HIV positive children and adults, b) retaining HIV positive clients in care, c) graduating OVC’s from vulnerability.

Uganda 2020-08-26 2023-08-26 Medical and Health Sciences Non-degree Award
ELIZABETH EKIRAPA-KIRACHO
ID: UNCST-2021-R013443
Activity-Based Costing and Management of HIV Services at the Facility Level in Uganda
REFNo: HS796ES

The main objective of this study is to obtain routine and accurate cost information on the provision of HIV and health services at the facility level and to use this information to effectively allocate resources, improve monitoring efforts, and increase efficiency. Specifically to;
1. To collect primary data on expenditure, utilization and service delivery of core HIV services from health facility providers and clients.

2. To collect secondary data on service delivery and HIV expenditures for core HIV services from health facilities.


Uganda 2020-08-26 2023-08-26 Medical and Health Sciences Non-degree Award
molly naisanga
ID: UNCST-2023-R005602
THE IMPACT OF KNOWLEDGE, PERCEPTIONS AND BELIEFS OF PATIENTS’ ABOUT ANTICOAGULATION AND THEIR ASSOCIATION WITH INTERNATIONAL NORMALIZED RATIO CONTROL IN UGANDA AND SOUTH AFRICA MIXED METHODS STUDY
REFNo: HS609ES

1. To describe the relationship between patients’ beliefs about warfarin and INR control.
2. To explore patients’ knowledge, perceptions and beliefs about warfarin treatment in Ugandan and South African patients receiving anticaogulation.
3. To explore the knowledge, perceptions and practices of Ugandan and South African health care providers about provision of warfarin.

Uganda 2020-08-24 2023-08-24 Medical and Health Sciences Non-degree Award
Mohammed Lamorde
ID: UNCST-2019-R001293
An open-label, randomized, single intravenous dosing study to investigate the effect of fixed dose combinations of tenofovir/lamivudine or atazanavir/ritonavir on the pharmacokinetics of remdesivir in Ugandan healthy volunteers
REFNo: HS654ES

Primary objectives
1. To assess the safety and tolerability of single intravenous doses of remdesivir in adult healthy volunteers
2. To evaluate the intracellular pharmacokinetics of single dose intravenous remdesivir with or without co-administration of oral fixed-dose combination tenofovir/lamivudine with patients serving as their own controls

Secondary objectives
1. To evaluate the difference in plasma and intracellular pharmacokinetics of intravenous remdesivir among healthy volunteers receiving tenofovir/lamivudine versus healthy volunteers receiving tenofovir/lamivudine plus atazanavir/ritonavir tablets.
2. To generate a population pharmacokinetic model to describe inter-individual variability in intracellular pharmacokinetics of remdesivir

Nigeria 2020-08-24 2023-08-24 Medical and Health Sciences Non-degree Award
DEUS KAMYA
ID:
In-vitro activity of mycobacteriophages against Mycobacterium tuberculosis biofilms
REFNo: HS774ES

1. To characterize the lytic activity of mycobacteriophages using Mycobacterium smegmatis mc2155 as host bacterium
2. To determine mycobacteriophage host range on a panel of 50 clinical isolates of Mycobacterium tuberculosis
3. To determine the inhibitory and disruptive effect(s) of mycobacteriophages on Mycobacterium tuberculosis-biofilms
Uganda 2020-08-24 2023-08-24 Medical and Health Sciences Degree Award
CATHERINA NAZZIWA
ID:
Perspectives on Genetic Research and Curative Therapies for Sickle Cell Disease
REFNo: SS520ES

The main objective of this study is to assess perspectives of diverse sickle cell disease stakeholders in Uganda regarding participation in genetics research and curative therapies for sickle cell disease, and to identify the related key ethical, social and cultural issues.
Uganda 2020-08-24 2023-08-24 Social Science and Humanities Degree Award
CATHERINE ABBO
ID:
Incorporating mental health and psychosocial support in the Ugandan Police Child and Family Protection Department toll free line to address sexual and gender-based violence (SGBV) complaints.
REFNo: HS791ES

1. To explore the understanding of TFLOs regarding MHPSS needs of complainants of SGBV. 2. To develop and implement a mental health and psychosocial support training for 20 TFLOs working in Kampala and Wakiso Districts. 3. To conduct an evaluation of the training programme among the TFLOs.
Uganda 2020-08-24 2023-08-24 Medical and Health Sciences Degree Award
Gilbert Habaasa
ID:
Death registration completeness, gendered Social norms and Behavioural practices affecting death registration in Uganda
REFNo: SS539ES

i. To establish the prevalence of death registration in HDSS sites of Uganda (absolute number of deaths registered).
ii. To find out the level of data quality for death registration in HDSS sites of Uganda
(death registration completeness, timeliness of death registration).
iii. To generate gendered vital statistics using existing death data in HDSS sites of Uganda (Age Specific Mortality Rates, Life expectancy at birth and cause of death by age and gender)
iv. To find out the gendered social norms and behavioral practices that lead to under-registration of deaths in Uganda.

Uganda 2020-08-24 2023-08-24 Social Science and Humanities Non-degree Award
Faith Sebuliba Rosemary Kasumba
ID:
To explore Nursing Students Readiness to Learn in a Technology Enhanced Environment in Degree Completion Programs in Institutions of Higher Education in Uganda
REFNo: HS716ES

i.Describe nursing student self-efficacy of technical competencies that promote, their readiness to learn in technology enhanced environments.
ii.Describe personal attributes associated with nursing students’ readiness to learn in technology enhanced environments.
iii.Determine institutional support that promote nursing students readiness to learn in technology enhanced environments.
iv.Determine nursing students’ perspectives regarding their readiness to learn in a technology enhanced environment.

Uganda 2020-08-21 2023-08-21 Medical and Health Sciences Degree Award
View Sort By:

"A prosperous Science and Technology Led Ugandan Society."