Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Julius Okuni Boniface
ID: UNCST-2019-R000963
PERFORMANCE OF SELECTED NOVEL MOLECULAR POINT OF CARE DIAGNOSTICS FOR EMERGING AND ONGOING EPIDEMICS AND ANTIMICROBIAL RESISTANCE IN UGANDA (PREPARE-TID)
REFNo: A584ES

General Objective To validate novel rapid molecular assays in nucleic acid extraction, point of care testing and One health surveillance of AMR, CCHF, RVF and other arthropod borne pathogens responsible for emerging and ongoing epidemics in Uganda Specific Objectives (i) To determine the prevalence of Congo Crimean Haemorrhagic fever (CCHF) in different tick species collected at Kampala City Abattoir. (ii) To determine the diagnostic performance of a novel NA extraction on selected Assays for rapid detection of CCHF, RVF and AMR. (iii) To determine the diagnostic performance the multiplex qPCR-based Point of Care diagnostic assay for detection of CCHF, RVF and AMR. iv) To appraise the existing one health point of care diagnostics for detection of zoonotic pathogens using a meta-analysis. (v) To determine the reliability of novel next generation sequencing platform for detection of AMR markers for Staphylococcus aureus, E. coli, Klebsiella, Pseudomonas aeruginosa from waste water samples.
(vi) To document the conditions required for the optimal performance of the test protocols.
(vii) To evaluate the field performance of the Multiplex qPCR one Health point of care diagnostic and the reliability of novel Next Generation platform in an emergency outbreak situation.

Uganda 2025-04-11 15:16:42 2028-04-11 Agricultural Sciences Non-Clinical Trial Non-degree Award
Fred Kaggwa
ID: UNCST-2022-R008842
Dialogues of Delivery: Fine-Tuning Large Language Models for Prenatal and Perinatal Care in East African Languages
REFNo: HS5739ES

General Objective
To develop, evaluate, and deploy an open-source fine-tuned Large Language Model capable of answering prenatal and perinatal care questions in Luganda, Runyankore-Rukiga, and Swahili, thereby enhancing access to relevant health information among expectant mothers.
Specific Objectives
1. Collect, curate, and build high-quality clinical text corpora and datasets specific to these languages and healthcare needs.
2. Develop a pipeline for fine-tuning domain-specific LLMs to support prenatal and perinatal care in Luganda, Runyankore-Rukiga, and Swahili.
3. Deploy and evaluate the effectiveness of the fine-tuned domain-specific LLMs in community health settings, ensuring linguistic, cultural, and contextual relevance.

Uganda 2025-04-11 15:13:35 2028-04-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Omulepu Isaac
ID: UNCST-2022-R003531
PREVALENCE AND FACILITATORS OF RESPECTFUL MATERNITY CARE DURING CHILDBIRTH AMONG WOMEN IN IN KAYUNGA REGIONAL REFERRAL HOSPITAL AND IMPACT OF DISRESPECTFUL AND ABUSIVE CARE ON MATERNAL HEALTH SEEKING BEHAVIOR
REFNo: HS5710ES

1. To determine the prevalence of RMC during childbirth among women in Kayunga RRH .
2. To assess for the facilitators of RMC during childbirth among women in Kayunga RRH
3. To explore the impact of disrespectful and abusive care of women during childbirth to maternal health seeking behavior.

Uganda 2025-04-11 14:48:37 2028-04-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nicolas Laing
ID: UNCST-2024-R015317
The impact of patient preferences, knowledge and attitudes on the demand for and supply of formal health care in Uganda
REFNo: SS3699ES

Objecitve,
New Zealand 2025-04-11 14:45:57 2028-04-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
Japheth Noel
ID: UNCST-2021-R013959
The Role of Inclusive Practices on Academic Resilience and Retention among Refugee Secondary School Students: A case of Nakivale Refugee Settlement Camp, Uganda
REFNo: SS3750ES

To examine the role of inclusive practices on academic resilience and retention among refugee secondary school students in Nakivale refugee settlement camp in Uganda.,(v) To analyze the relationship between academic inclusive practices and retention among secondary school students in Nakivale refugee settlement camp.,To determine the relationship between social inclusive practices and retention among secondary school students in Nakivale refugee settlement camp.,To analyze the relationship between academic inclusive practices and academic resilience among secondary school students in Nakivale refugee settlement camp.,To examine relationship between social inclusive practices and academic resilience among secondary school students in Nakivale refugee settlement camp.,To explore social and academic inclusive practices among secondary schools in Nakivale refugee settlement camp, in Uganda.,
Uganda 2025-04-11 14:40:49 2028-04-11 Social Science and Humanities Non-Clinical Trial Degree Award
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