Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Solomon Wafula Tsebeni
ID: UNCST-2021-R013883
 Assessment of indoor air quality, risk factors and potential health effects among residents in an urban informal settlement in Kampala, Uganda
REFNo: SS996ES

To describe the potential health effects associated with indoor air pollution. ,To assess the factors associated with indoor air pollution among households. ,To determine the levels of indoor PM2.5, and Carbon monoxide (CO) in households., To determine levels of indoor air pollution, its associated risk factors and potential health effects among residents in an informal settlement in Kampala so as to generate information that can be used in design appropriate strategies, policies and practices that promote good air quality in households, hence mitigate health problems associated with indoor air pollution. ,
 Uganda 2021-09-03 2024-09-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
Amy  Ritterbusch Elizabeth
ID:
Child Protection Mapping and Honour
REFNo: SS970ES

1.To examine the effect of global narratives of child wellbeing on child protection and rights practices in Uganda
2.To explore prospects for local child protection practices in informing and enriching global child protection policy
3.To explore the concept of honour and examine how it promotes children’s wellbeing and or sustains violence against children in the Ugandan context.

USA 2021-09-03 2024-09-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jesca Nantume
ID: UNCST-2021-R013984
 Knowledge, attitudes and practices towards the tobacco use control measures among teenagers aged (13-19) years; A cross sectional study in the slum areas of Kampala Uganda
REFNo: SS988ES

To evaluate knowledge, attitudes and practices towards tobacco control among teenagers
aged (13-19) years
1. To evaluate existing control measures among teenagers
2. To assess the knowledge, attitudes, and practices of the current tobacco control
measures among teenagers.
3. To evaluate the cause of initiation of tobacco use in slums among teenagers
 Uganda 2021-09-03 2024-09-03 Social Science and Humanities Non-Clinical Trial Degree Award
Danette Cagnet Lee
ID:
Community-led Total Sanitation Programming and the Maintenance of Sanitation Behaviors
REFNo: SS737ES

The purpose of this qualitative, exploratory, case study research is to better understand stakeholder's, including village community members, village leadership, and CLTS practitioner, perceptions of the facilitators and hindrances to the maintenance of sanitation in the maintenance stage of Community-led Total Sanitation programming in Uganda, East Africa. This study seeks the perspective of and participation of village community stakeholders receiving the Community-led Total Sanitation intervention implemented by the non-governmental organization, Kibo Group International.
 USA 2021-09-02 2024-09-02 Social Science and Humanities Non-Clinical Trial Degree Award
Joyce Kambugu Balagadde
ID: UNCST-2020-R014996
 Acute Leukemia Banking and Biology Study for Patients at the Uganda Cancer Institute.
REFNo: HS1590ES

1. To determine the genomic profile of patients with acute leukemia and identify the prevalence of various fusions and mutations in these patients.
2. To collect and store corresponding subjects’ medical information including diagnosis and disease characterization, laboratory and imaging studies, treatment, and outcome.

 Uganda 2021-09-02 2024-09-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
John Baptist Asiimwe
ID: UNCST-2021-R013716
 The Traditional Medicine Practitioner’s Concept of Cancer, its Care, Herbal medicine use and the Patients Perceived benefits (Clinical outcomes) in Selected Districts of Central Uganda.
REFNo: HS1602ES

1. To establish the prevalence and predictors of the use of herbal medicines’ in cancer
2. To explore the concept of cancer and its care in traditional medicine as perceived by traditional medicine practitioners (TMPs) in selected districts of central Uganda
3. To document the herbs used by traditional medicine practitioners (TMPs) to manage cancer in selected districts of central Uganda.
4. To determine the clinical outcomes in patients with cancer treated by traditional medicine practitioners (TMPs).

 Uganda 2021-09-02 2024-09-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Moses Adriko
ID: UNCST-2019-R001787
 Gaining community insights into societal causes of and solutions for schistosomiasis transmission hotspots (InSight-ScHot)
REFNo: HS1616ES

To identify non-mass administration preventative chemotherapeutic control measures for schistosomiasis that members of the community see as implementable
 Uganda 2021-09-02 2024-09-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Enock Matovu
ID:
Identification of the Genetic Markers of Trypanotolerance in Indigenous Cattle of Apach District, Northern Uganda
REFNo: NS247ES

Main Objective
To identify genetic markers of Animal African Trypanosomiasis (AAT) tolerance in indigenous cattle

Specific Objectives

i. To set up a panel of phenotypically characterized indigenous cattle with respect to AAT susceptibility

ii. To develop a data base of reference genomes and transcriptomes of indigenous cattle from an AAT endemic region of mid-northern Uganda
iii. To determine the genotypes associated with trypanotolerance in indigenous cattle

 Uganda 2021-08-31 2024-08-31 Natural Sciences Non-Clinical Trial Non-degree Award
Rhoda Wanyenze
ID: UNCST-2021-R013352
 Assessment of the Implementation Processes and Outcomes of the HIV Assisted Partner Notification Program, Ministry of Health, Uganda
REFNo: HS1671ES

3.2 General Objective
To assess the Implementation processes and outcomes of the HIV Assisted Partner Notification Program in Uganda
3.3 Study Objectives
1. To determine the current level of uptake of APN services and the factors associated with uptake of these services among HIV index clients.
2. To assess the acceptability and uptake of APN services among a sub-sample of partners of APN clients.
3. To assess the extent to which the existing service delivery environment influences the delivery of APN services.
4. To document the perceptions and experiences of users of APN services, challenges faced in utilizing APN services and concerns those users have regarding the way APN services are provided.
5. To determine the positive and negative outcomes of APN services in Uganda, and the support mechanisms available for those who experience negative outcomes.
6. To document the barriers to and facilitators of successful APN implementation and the challenges implementers face during APN implementation.
7. To document the existing opportunities that can inform the future scale-up of the APN program.

 Uganda 2021-08-31 2024-08-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Pontiano Kaleebu
ID: UNCST-2021-R013577
 A behavioural Science Research to Determine Factors that Facilitate Future Uptake of HIV Prevention Products and Multi-Purpose Prevention Technologies to Prevent HIV and Unwanted Pregnancy in Sub-Saharan Africa Universally Accessible HIV Prevention Technologies for African Girls and Young Women through Knowledge Applied from Behavioural Economics (UPTAKE)
REFNo: HS1540ES

Multi-purpose Prevention Technologies (MPTs) to prevent HIV and unwanted pregnancy in Sub-Saharan Africa

i. To understand facilitators of and barriers to uptake and retention of injectable and implantable long acting pre-exposure prophylaxis (LA-PrEP) and MPT to inform product development, using formative behavioural research methods
ii. To design interventions to impact the uptake of new biomedical HIV prevention products, as part of a suite of self-care and self-screening products for sexual and reproductive health, using quantitative behavioural research methods
iii. To test the effectiveness of the alternate design/interventions and strategies, using marketed LA contraceptive products as proxies for LA HIV prevention products in development
iv. To estimate the cost of retention interventions and the cost effectiveness of products and delivery methods among adolescent girls and young women (AGYW) and female sex workers (FSWs) for prevention of pregnancy and/or HIV, using modelling

 Uganda 2021-08-31 2024-08-31 Medical and Health Sciences Clinical Trial Non-degree Award
Emmy Okello
ID: UNCST-2020-R009792
 “Active Case Detection and Decentralized Dynamic Registry to Improve the Uptake of Rheumatic Heart Disease Secondary Prevention” (ADD-RHD)
REFNo: HS1561ES

Secondary objectives include technical proficiency, acquisition times, global image quality, and user satisfaction and confidence. Each of these parameters will be reported for the entire training group and a sub-group analysis will look for differences between curriculum groups. Acquisition times and image quality will be compared between trainees and expert sonographers.,To determine the impact of a pragmatic RHD primary prevention program in Uganda,
 Uganda 2021-08-30 2024-08-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Comfort Mukasa Hajra
ID:
Real-time access to sanitation information for improved management of sanitation services: A case Study in Kawempe division.
REFNo: HS1458ES

Main Objective:
To test if timely access to sanitation information leads to improved sanitation planning, increased access to safely managed sanitation services and improved multi-sectoral collaboration.

Specific Objectives:
1. To design and test the effectiveness of timely access to sanitation information for planning, coordination and access to improved sanitation services.
2. To validate user needs for sanitation service provision in Uganda.
3. To document scalable best practice mechanisms for improved multi-sectoral planning and coordination on sanitation.
 Uganda 2021-08-30 2024-08-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eric Awich Ochen
ID: UNCST-2021-R013266
 Preventing Gender-based Violence: Video Game Intervention Designed as an Educational Tool to Address Child Marriage in Uganda
REFNo: SS880ES

To assess the effectiveness of the game (Peace) in promoting pro-social attitude/behavior change and empathic capacity among young people to prevent violence.
• Help young people understand what sexual exploitation is and how it is linked to gender inequalities.
• Increase young people’s understanding about how adult power is misused to abuse and silence them.
• Show young people that perpetrators will seek out and exploit young women’s vulnerabilities.
• Help young people understand the impact that sexual coercion has on everyone involved.
• Empower young people in reporting incidents of child sexual abuse and sexual coercion.
• Increase awareness of the role of various agencies/individuals that can help.
• Help young people understand ways in which adults may groom them using various tactics.
• Help young people understand the relationship between sexual coercion and child marriage.
• Give young people the opportunity to develop skills, knowledge, and competencies that can help them make sound decisions for themselves or others in real life situations.
• To support and empower young people in avoiding child marriage


Uganda 2021-08-30 2024-08-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
NAMANDE MUGERWA SARAH
ID:
“EKISAAKAATE” (ROYAL ENCLOSURE) PEDAGOGY AND EARLY CHILDHOOD MORAL LEARNING OUTCOMES IN BUGANDA KINGDOM IN UGANDA
REFNo: SS975ES

To establish the mediating relationship between multiculturalism and early childhood moral learning outcomes.,To examine the relationship between “ekisaakaate” role play instruction pedagogy and early childhood moral learning outcomes.,To determine the relationship between “ekisaakaate” traditional story telling instruction pedagogy and early childhood moral learning outcomes.,To establish the relationship between “ekisaakaate” living values-based contextual instruction pedagogy and early childhood moral learning outcomes.,To find out the relationship between “ekisaakaate” native language instruction pedagogy and early childhood moral learning outcomes. ,
 Uganda 2021-08-30 2024-08-30 Social Science and Humanities Non-Clinical Trial Degree Award
Lazaaro Mujumbusi
ID: UNCST-2023-R007470
 Exploring understandings of and attitudes towards Covid-19 in Mayuge district Uganda
REFNo: SS977ES

1. To explore community members' perceptions of COVID-19 and its transmission, with a focus on ideas about responsibility.
2. To investigate how ideas about responsibility intersect with existing inequalities around occupation, tribe, and gender.
3. To examine whether, and how, understandings of COVID-19 transmission have impacted everyday WaSH practices.
4. To develop insight that may be of value to developing interventions aimed at reducing transmission and/or stigma.

Uganda 2021-08-30 2024-08-30 Social Science and Humanities Non-Clinical Trial Degree Award
Patrick  Vudriko
ID:
Survey to identify priority livestock diseases and diagnostic needs of animal health professionals and farmers in Central and Southwestern Uganda
REFNo: A84ES

Specific objectives
1. To identify the priority livestock and poultry diseases for which diagnostic services and diagnostic kits/aids are needed by various stakeholders (farmers, vets).
2. To assess the perception and attitudes of key stakeholders in the animal industry on the value and quality of existing animal diagnostic services in Uganda

 Uganda 2021-08-27 2024-08-27 Agricultural Sciences Non-degree Award
Suzanne  Kiwanuka N
ID: UNCST-2020-R014671
 Using High Impact Communication Strategies to increase blood donation awareness among secondary school students in Uganda
REFNo: SS802ES

1. To increase knowledge and awareness about blood donation among secondary school students in Uganda using targeted communication strategies.
2. To increase willingness to donate blood among secondary school students in Uganda using targeted communication strategies
3. To increase intention to donate blood among secondary school students in Uganda using targeted communication strategies

 Uganda 2021-08-27 2024-08-27 Social Science and Humanities Non-degree Award
Christine Akello Kalumera Kalumera
ID: UNCST-2021-R013514
 OPTIMISING USER INVOLVEMENT IN USER STORIES COLLECTION, ANALYSIS AND DESIGN TASKS FOR EHIS DEVELOPMENT: APPLYING COLLABORATION ENGINEERING PRINCIPLES TO HUMAN CENTRED DESIGN
REFNo: SIR62ES

The main of objective of this research is to develop a collaborative engineering process to improve user involvement in requirements gathering, analysis and design and stages of the user centred design approach, when developing electronic health information systems
 Uganda 2021-08-27 2024-08-27 Engineering and Technology Non-Clinical Trial Degree Award
Olive Kobusingye Chifefe
ID:
Assessing the impact of COVID-19 on the mobility patterns in Kampala Metropolitan Area
REFNo: HS1636ES

To explore the socio-economic impact of implementing the regulations on transportation.,To describe ways in which transporters coped with the COVID-19 related restrictions on transport. ,To identify ways in which commuters coped with the threat of COVID-19., The overall objective of this study is to examine the impact of the COVID-19 pandemic on mobility patterns in the Kampala Metropolitan area so as to inform planning transportation during the pandemic and in the post-COVID-19 period. ,
 Uganda 2021-08-27 2024-08-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
BRENDA GATI MIREMBE
ID: UNCST-2021-R013390
 A Phase 3, Randomized, Active Controlled, Double-blind Clinical Study to Evaluate the Efficacy and Safety of Oral Islatravir Once Monthly as Pre-Exposure Prophylaxis in Cisgender Women at High Risk for HIV 1 Infection.
REFNo: HS1631ES

Primary Objectives:
1. To evaluate the efficacy of oral ISL QM compared to FTC/TDF QD for the
prevention of HIV-1 infection as assessed by the incidence rate per year of confirmed
HIV-1 infection.

2. To evaluate the safety and tolerability of oral ISL QM compared to oral FTC/TDF QD as assessed by review of the accumulated safety data

Secondary Objective
1. To evaluate the efficacy of oral ISL QM in reducing the incidence per year of HIV-1
infection relative to the background rate.

 Uganda 2021-08-27 2024-08-27 Medical and Health Sciences Clinical Trial Non-degree Award
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