Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Asenath Kwagalakwe
ID:
Dry Rifting in the Albertine-Rhino graben, Uganda (DRIAR)
REFNo: NS252ES

Investigating the physics of strain accommodation in the magma-poor Albertine-Rhino Graben of the East African Rift System using geodynamic modeling and GNSS geodesy
 Uganda 2021-09-20 2024-09-20 Natural Sciences Non-Clinical Trial Degree Award
Hillary Mwongyera
ID:
Dry Rifting in the Albertine-Rhino Graben (DRIAR)
REFNo: NS264ES

To conduct a geological investigation of faulting associated with continental rifting in the magma-poor rift environment in the northernmost Western Branch of the East African Rift System.
 Uganda 2021-09-20 2024-09-20 Natural Sciences Non-Clinical Trial Degree Award
Eleanor Namusoke Magongo
ID: UNCST-2021-R013199
 Determining the Effectiveness of Dispensing Messages (DEDIM) on Adherence and Viral Suppression among Children with an Unsuppressed Viral Load in Uganda
REFNo: HS1544ES

General Objective
To determine the effectiveness and implementation of dispensing messages on adherence and viral suppression among children with an unsuppressed viral load in Uganda

Specific objectives
1. To determine the facilitators and barriers to the delivery of dispensing messages to caregivers of children (< 15 years) living with HIV with an unsuppressed viral load in Uganda to inform the implementation strategy.
2. To assess the effectiveness of dispensing messages on outcomes of adherence and viral load suppression among children (<15 years) living with HIV with non-suppressed viral loads in Uganda.
3. To identify processes and contextual factors that explain the uptake, reach, and fidelity of delivery of ART dispensing messages to caregivers of children (< 15 years) living with HIV with unsuppressed viral load in Uganda

 Uganda 2021-09-20 2024-09-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eve  Namisango
ID: UNCST-2021-R014038
 The development and evaluation of a mobile phone-based intervention to facilitate continuity of care, symptom monitoring and self-management in palliative care patients in Uganda
REFNo: HS1600ES

vi. To develop best practices for patient-public engagement to empower cancer patients to support research in palliative care at different stages,v. To identify mechanisms of action for the intervention in supporting palliative care patients and their families ,iv. To determine uptake, patterns of clinical palliative care practice and factors influencing engagement with the mobile application ,iii. To deliver the novel intervention to two cohorts of palliative care patients , ii. To determine optimal implementation within routine palliative care practice at Yumbe Regional referral hospital palliative care unit and New Life Hospice ,i. To develop and evaluate a mobile phone-based (mpalliative) intervention to collect outcomes data and COVID-19, TB and hepatitis B symptoms from palliative care patients alongside developing a web-based application to communicate data to palliative care teams and facilitate continuity of care and self-management in palliative care patients in Uganda ,
 Uganda 2021-09-20 2024-09-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Achilles Katamba
ID: UNCST-2019-R000540
 Uganda TB Care Cascade
REFNo: HS1718ES

1. To evaluate the accuracy of DHIS2 TB surveillance data using quantitative and mixed-methods approaches. 1a. To compare the accuracy of TB quality indicators measured with aggregate data compared to those measured with individual-level data. 1b. To explore discrepancies in the DHIS2 data using qualitative interviews.
2. To use routine surveillance data to describe the quality of TB care in Uganda.
3. To measure the impact of Xpert MTB/RIF on TB indicators in Uganda.
 Uganda 2021-09-20 2024-09-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nelson Sewankambo K
ID: UNCST-2020-R014578
 THRiVE Research Enrichment: Community and Public Engagement for Enhanced Impact
REFNo: HS1586ES

1. To enable doctoral trainees to work with young people in schools who will identify their preferred ways for engagement with THRiVE research.
2. To co-create and co-design at least one engagement project at each school led by student champions in collaboration with doctoral trainees and implemented based on one or more ways identified in objective 1 above.
3. To co-design and implement at least one student-centred drama skit and/or games for engagement of students with THRiVE doctoral trainees’ research, utilizing findings from objective one.
4. To publicize the public engagement in research work to stakeholders as a way of stimulating engagement of young people and doctoral trainees in PER.

Uganda 2021-09-17 2024-09-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jane  Namusisi
ID: UNCST-2021-R013619
 seizure control and associated factors among children with epilepsy at Mbarara Regional Referral Hospital
REFNo: HS1657ES

MAIN OBJECTIVE
To determine the seizure control status and describe its associated factors among children attending the Epilepsy Clinic at MRRH for at least six months.
SPECIFIC OBJECTIVES;
1. To identify the seizure types among children under care for at least six months at the Epilepsy Clinic, MRRH.
2.To determine the proportion of children with epilepsy with poor seizure control under care for at least six months at the MRRH Epilepsy clinic.
3.To identify the factors associated with poor seizure control among children under care for at least six months at the MRRH Epilepsy clinic.

Uganda 2021-09-17 2024-09-17 Medical and Health Sciences Non-Clinical Trial Degree Award
Achilles Katamba
ID: UNCST-2019-R000540
 Human-Centred Design and Communities of Practice to Improve Delivery of Home based Tuberculosis Contact Investigation in Uganda
REFNo: HS1720ES

General Objective: The study aims to assess the effectiveness of an enhanced intervention strategy for implementing TB contact investigation relative to usual care. Specific Objectives: 1.To compare the implementation, effectiveness, and public health impact of TB contact investigation delivered via an enhanced intervention strategy vs. the usual care strategy in a stepped-wedge, cluster-randomized implementation trial. 2.To identify implementation processes and contextual factors that influence the effectiveness of the intervention strategy for TB contact investigation. 3.To compare the costs and epidemiological impact of the intervention and usual care strategies for TB contact investigation.
Uganda 2021-09-17 2024-09-17 Medical and Health Sciences Clinical Trial Non-degree Award
Susan  Nabadda Ndidde
ID: UNCST-2020-R014331
 SeqCOVID consortium: EAC participation – Sequencing of COVID-19 isolates from the East African Region
REFNo: HS1592ES

Epidemiological Analysis of current COVID outbreak,Capacity Building in East Africa and setting up of Prospective COVID Surveillance Platform,Diagnostic and Vaccine Development for East African COVID variants: - describe East African COVID variants and predict immunogenic epitopes and drug targets in silico, The aim of the present project is for the East African region to actively contribute data for COVID-19 drug and vaccine development, to equip the region for the time after a vaccine and drugs were developed and also to prepare for future outbreaks.,
 Uganda 2021-09-16 2024-09-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Grace Nalumu
ID:
ASSESSING FACTORS ASSOCIATED WITH NEONATAL DEATHS IN BUSIA DISTRICT; CASE STUDY OF MASAFU, DABANI AND BUSIA HEALTH FACILITIES
REFNo: HS1711ES

1. To assess factors associated with neonatal deaths in Busia district such that we make recommendations, according to the findings, on what measures to adopted in order to reduce neonatal mortality in the district and the country,4. To examine health facility factors associated with neonatal deaths in Busia district,3. To establish neonatal related factors associated neonatal deaths in Busia district ,2. To determine maternal factors associated with neonatal deaths in Busia district ,
 Uganda 2021-09-16 2024-09-16 Medical and Health Sciences Non-Clinical Trial Degree Award
Janet SEELEY
ID:
Multimorbidity in Africa - Increasing Understanding of the Health Workers’ Experiences and Epidemiology (MAfricaEE)
REFNo: SS998ES

Explore the healthcare professionals' (HCPs) experiences of treating and managing patients with multi-morbidity in Uganda and what health workers see as the main barriers to optimal care provision. How do health care professiönals view the potential impacts of COVID-19 on care for patients with multi-morbidity?
 UK 2021-09-13 2024-09-13 Social Science and Humanities Non-Clinical Trial Non-degree Award
Frederick  Oporia
ID:
Improving use of seaworthy life jackets among boaters on Lake Albert, Uganda. A cluster randomized trial
REFNo: SS992ES

1. To estimate the prevalence of life jacket use among boaters on Lake Albert.

2. To identify the determinants of life jacket use among boaters on Lake Albert

3. To determine the seaworthiness of life jackets used by boaters on Lake Albert

4. To design a behavior change intervention aimed at improving use of seaworthy life jackets among boaters on Lake Albert

5. To pilot and evaluate the effectiveness of a behavior change intervention on improving use of seaworthy life jackets among boaters on Lake Albert

 Uganda 2021-09-10 2024-09-10 Social Science and Humanities Degree Award
Carolyn Pelnik
ID:
Identifying and Easing Constraints on Microenterprise Location within Kampala, Uganda
REFNo: SS935ES

This project asks whether business relocation within the city could increase profits for microfirms in Kampala, Uganda, and if so, then what frictions (constraints) restrict a firm’s ability to relocate without intervention. Ultimately, this project plans to use a multi-arm randomized experiment to accomplish 3 aims: to detect appetite for business relocation, whether relocation increases profits, and which of the tested frictions might constrain location choice. In the first phase of the research, the project will survey microfirms in Kampala to understand their current locations, how profits vary by location across the city, what aspirations the business owners have with respect to future business growth, and what challenges they perceive to accomplishing business growth.
USA 2021-09-10 2024-09-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Paineto Masengere
ID: UNCST-2021-R013195
 Perceptions, barriers, and facilitators of adoption of healthy lifestyles for cardiovascular disease prevention among slum communities in Kampala, Uganda
REFNo: HS1661ES

1. To explore how slum dwellers in Kampala district define a healthy lifestyle in the context of cardiovascular disease prevention.
2. To explore the barriers and facilitators to adopting recommended lifestyles for cardiovascular disease prevention among slum dwellers.
3. To explore the potential roles of community actors in slums in cardiovascular disease prevention.

Uganda 2021-09-10 2024-09-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Felix Oyania
ID: UNCST-2021-R013492
 Feasibility of Primary Repair for Anorectal Malformations in Uganda
REFNo: HS1632ES

To determine the feasibility of primary repair for anorectal malformations in Uganda.,
 Uganda 2021-09-10 2024-09-10 Medical and Health Sciences Non-Clinical Trial Degree Award
FRANK MULINDWA
ID:
Changes in insulin kinetics after withholding dolutegravir in Ugandan HIV patients who develop diabetes while on dolutegravir.
REFNo: HS1493ES

To determine changes in; insulin secretion, insulin sensitivity, insulin clearance and HBA1C at 24 weeks after DTG discontinuation in Ugandan HIV patients who develop diabetes while on DTG.
 Uganda 2021-09-09 2024-09-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Martha Musyoka Mbenia
ID:
PREDICTORS OF ADVERSE FETO-MATERNAL OUTCOMES AMONG MOTHERS ADMITTED WITH ANTEPARTUM HEMORRHAGE AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS1450ES

To describe adverse outcomes and determine predictors of adverse feto-maternal outcomes in mothers with antepartum hemorrhage at Mbarara Regional Referral Hospital
 Kenya 2021-09-09 2024-09-09 Medical and Health Sciences Clinical Trial Degree Award
Jimmyy Opee
ID:
PROPORTION AND FACTORS ASSOCIATED WITH INTRA-PROCEDURAL PAIN AMONG WOMEN UNDERGOING MANUAL VACUUM ASPIRATION FOR INCOMPLETE ABORTION AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS1462ES

General objective
To determine the proportion and factors associated with intra-procedural pain among women undergoing Manual Vacuum Aspiration for incomplete abortion at gynecology ward at Mbarara Regional Referral Hospital.

Specific objectives
1. To determine the proportion of women with intra-procedural pain undergoing Manual Vacuum Aspiration for incomplete abortion at gynecology ward at Mbarara Regional Referral Hospital.
2. To determine the factors associated with intra-procedural pain among women undergoing Manual Vacuum Aspiration for incomplete abortion at gynecology ward at Mbarara Regional Referral Hospital.

 Uganda 2021-09-09 2024-09-09 Medical and Health Sciences Non-Clinical Trial Degree Award
Ronald Mulebeke
ID:
A pilot study to assess the impact of Supportive Supervision and Behavior Change Communication at private health facilities in Uganda
REFNo: HS1588ES

This study will assess the impact of supportive supervision and behaviour change communication to improve the quality of malaria care and data management delivered by clinicians at private health facilities in Uganda.
Uganda 2021-09-09 2024-09-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ANTHONY KAYIIRA
ID: UNCST-2020-R014108
 Understanding Reproductive Health among Survivors of Paediatric and Young adults (URHSPY) Cancers: a mixed method study
REFNo: HS1652ES

To explore the knowledge, perceptions, and attitude of; parents or caretakers of children with cancer, and health workers on cancer treatment-related reproductive morbidity, at the Uganda Cancer Institute,To describe self-reported reproductive morbidity associated with cancer treatment among childhood and young-adult cancer survivors.,To establish the extent of reproductive morbidity associated with cancer treatment among young cancer survivors in Uganda. In addition, we aim to explore the contextual enablers and barriers to addressing cancer treatment-related reproductive morbidity in Uganda.,
 Uganda 2021-09-09 2024-09-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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