Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Iga  David
ID:
ENTREPRENEURIAL SUCCESS AMONG MICRO ENTREPRENEURS IN UGANDA
REFNo: SS2258ES

1. To examine the relationship between
psychological capital and entrepreneurial
success.
2. To contrast the relationship between
emotional intelligence and entrepreneurial
success.
3. To relate the relationship between
individual learning behaviors and entrepreneurial success.
4. To explore the relationship between
entrepreneurial bricolage and entrepreneurial success.
5. To test the combined mediation effect of
entrepreneurial bricolage in the
relationship between psychological
capital, emotional intelligence, individual
learning behaviors and entrepreneurial
success.

Uganda 2024-02-13 18:05:55 2027-02-13 Social Science and Humanities Non-Clinical Trial Degree Award
Derrick Semugenze
ID: UNCST-2023-R007934
Association of human cytomegalovirus (HCMV) and other viral exposure with susceptibility and progression to tuberculosis disease
REFNo: HS3255ES

Association of HCMV and other viral infections with tuberculosis progression among household and close contacts to tb index cases,Association of human cytomegalovirus (HCMV) exposure with tuberculosis susceptibility in TB presumptive children from Uganda,Association of human cytomegalovirus (HCMV) exposure with tuberculosis susceptibility in TB presumptive adults from Uganda,Association of human cytomegalovirus (HCMV) exposure with tuberculosis susceptibility in TB presumptive adults from South Africa,Association HCMV and other viral infections with susceptibility and progression to tuberculosis disease,
Uganda 2024-02-13 18:03:22 2027-02-13 Medical and Health Sciences Non-Clinical Trial Degree Award
Tobby Agwe Michael
ID:
Production and Cleansing of Biogas from Bio-degradable Municipal Solid Waste – A Way of Resource Recovery
REFNo: SIR276ES

• To Design and fabricate the system components of the biogas production plant.
• To prepare the organic fraction of the Municipal Solid Wastes.
• To anaerobically digest the Shredded Biodegradable Municipal Solid wastes.
• To cleanse the biogas.

Uganda 2024-02-13 17:57:42 2027-02-13 Engineering and Technology Non-Clinical Trial Non-degree Award
Alain Favina
ID:
Preparedness of private health workers in Mbarara City about identifying and managing Ebola outbreaks
REFNo: HS3424ES

To determine the relationship between the wellbeing of private health workers and their preparedness towards the Ebola outbreak in Mbarara city,To determine the knowledge, attitude, and practice towards the Ebola outbreak by health workers in private clinics in Mbarara city.,To determine the level of preparedness for the Ebola outbreak by health workers in private clinics in Mbarara City,
Burundi 2024-02-13 17:56:53 2027-02-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Betty Mwesigwa
ID: UNCST-2020-R014667
Sabin 003: A Phase 2, Randomized, Double-blind, Placebo-Controlled Trial to Evaluate Safety, Tolerability, and Immune Responses of an Investigational Monovalent Chimpanzee Adenoviral-Vectored Sudan Ebolavirus Vaccine in Healthy Adults
REFNo: HS3628ES

To evaluate the safety and tolerability of cAd3-EBO S vaccine
Uganda 2024-02-13 17:35:43 2027-02-13 Medical and Health Sciences Clinical Trial Non-degree Award
Friday Christopher
ID: UNCST-2023-R007260
SUSTAINABLE LAND MANAGEMENT PRACTICES AND ENVIRONMENTAL PROTECTION IN KABALE DISTRICT, UGANDA
REFNo: SS2370ES

i. To examine the effect of agroforestry on environmental protection in Kabale district, Uganda. ii. To determine the influence of crop rotation on environmental protection in Kabale district, Uganda. iii. To assess the effect of trenches and check dams on environmental protection in Kabale district, Uganda. iv. To establish the influence of mulching on environmental protection in Kabale district, Uganda. v. To evaluate the effectiveness of government policies in promoting environmental protection in Kabale district, Uganda.
Uganda 2024-02-09 23:38:35 2027-02-09 Social Science and Humanities Non-Clinical Trial Degree Award
Josephine Nayiga
ID: UNCST-2023-R005839
Addressing bioethical challenges in HIV research to inform the development of a training program at Makerere University
REFNo: HS3771ES

3. Identify the preferences of trainees regarding future training in bioethics and ascertain their perceived knowledge gaps related to research bioethics,2. Investigate the perspectives of senior investigators at IDI and faculty members at Makerere University based on their experiences, focusing on the ethical dilemmas encountered by trainees engaged in HIV research,1. Evaluate the existing level of awareness and knowledge concerning bioethical challenges in HIV research among current and former trainees at IDI and the School of Medicine, Makerere University,To understand the training needs in research bioethics for trainees in the area of HIV and co-infections, in order to inform the development of a training program at Makerere University,
Uganda 2024-02-09 23:36:15 2027-02-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
David  Ejalu Livingstone
ID:
ART Adherence among HIV-positive virally unsuppressed adolescents and young people: feasibility, acceptability, and effectiveness of a community-based implementation strategy to optimise compliance with intensive adherence counselling in East-Central Uganda.
REFNo: HS3807ES

1. To determine the level of compliance to IAC and the associated factors among virally unsuppressed Adolescents and Young People living with HIV in East Central Uganda.
2. To explore individual and system-level barriers to and facilitators of compliance to intensive adherence counselling protocol for enhancing ART adherence among unsuppressed Adolescents and Young People living with HIV in East-central Uganda.
3. To design a multifaceted theory-informed community-based IAC Implementation Strategy to optimize adherence for enhancing VLS among unsuppressed AYP in East-central Uganda.
4. To Evaluate the feasibility, acceptability, and effectiveness of a multifaceted theory-informed community-based IAC Implementation Strategy to optimize adherence among unsuppressed AYP in East-central Uganda.

Uganda 2024-02-09 23:35:00 2027-02-09 Medical and Health Sciences Non-Clinical Trial Degree Award
Peter Elyanu James
ID: UNCST-2021-R013210
Closing TB Gaps using patient-centered approaches to improve TB Screening, Diagnosis and Prevention among people living with HIV
REFNo: HS3664ES

To assess the performance of novel TB screening algorithms among children,
adolescents, and adults living with HIV and presenting for routine care across a network
of family centered HIV clinics in Uganda and other four sub-Saharan African countries as
compared to the current WHO recommended symptom-based screening strategy.
To compare new diagnostic strategies leveraging the evaluation of multiple specimens
(stool and oral swab Xpert Ultra, early morning urine LF-LAM, point-of-care ultrasound
(POCUS), and a design locked Xpert Host Response Test against a reference standard
(Xpert Ultra on spot and early morning respiratory specimens) to improve diagnostic yield.
To compare the proportion of PLHIV who initiate and complete TPT with 3HP or 6H within
the context of a patient centered differentiated service delivery model allowing selection
of TPT regimen and randomly allocating enhanced adherence support versus the
standard of care for TPT and adherence support.
To evaluate the cost-effectiveness of screening and diagnostic strategies as well as
comparative TPT regimens for the prevention of TB disease among children, adolescents
and adults living with HIV
Uganda 2024-02-09 23:32:58 2027-02-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Josephine Birungi
ID: UNCST-2023-R005605
A Family centred approach to enhance lifestyle change and behavioural modification for prevention of cardiovascular diseases among adolescents and their families in Uganda (FaCe-D) study
REFNo: HS3682ES

Main Objective
1. 1. We aim to explore the knowledge on cardiovascular health including CVD risk, perceptions and attitudes of participants, providers and other stakeholders towards the ihealth-T2D family-centered approach (FCA) as an intervention, obtain their input in the modification and design of the intervention to make it appropriate for Ugandan context
Specific Objectives
1. To explore the knowledge on cardiovascular health, perceptions, preferences and recommendations from potential participants on the proposed family-centered approach as an intervention for reducing and controlling common CVD risk factors among adolescents and their families.
2. To identify potential facilitators and barriers to adapting and implementing the FCA intervention in Uganda.
3. To use the data generated to design implementation strategies to promote the delivery, and uptake of the adapted FCA
Uganda 2024-02-09 23:29:31 2027-02-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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