Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
Search By Approval Date:
Clear Filter Total: 5,299
Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Paul  Kutyabami
ID: UNCST-2020-R015029
THE EFFECT OF COVID-19 OUTBREAK ON ONGOING RESEARCH PROCESSES IN UGANDA: KEY STAKEHOLDER’S EXPERIENCES, OPINIONS AND COPING STRATEGIES
REFNo: HS910ES

1.To explore the experiences of key stakeholders involved in research during Covid-19 outbreak in Uganda
2.To explore opinions and strategies regarding conduct of research during epidemic outbreaks in Uganda.

Uganda 2020-11-24 2023-11-24 Medical and Health Sciences Non-degree Award
Viola Karungi
ID:
Critical Theatre: An Analysis of Plays Representing the concepts of Violence, Injustice and the nature of Imperialism in regard to the War (1987-2006) in Northern Uganda.
REFNo: SS605ES

The major research question for the study is:
i. How do the plays Silent Voices, Forgotten World and Forged in Fire about the war in northern Uganda contribute to understanding the role of contemporary critical theatre in light of Uganda’s history of critical theatre?
The sub-questions are:
i. How do the plays represent the concept of violence on victims of the war in northern Uganda?
ii. How do the plays expose the nature of imperialism by the donor countries and institutions from the West that gave donor and humanitarian aid during the war and in its immediate aftermath?
iii. How do the plays represent the concept of injustice and how it is shaped by violence and imperialism regarding the war in northern Uganda?


Uganda 2020-11-23 2023-11-23 Social Science and Humanities Degree Award
Stella Neema
ID: UNCST-2019-R000814
Evaluation of UNICEF’s District Health Systems Strengthening Initiative (DHSSi) – Uganda Study Protocol
REFNo: SS613ES

The overall objectives of the evaluation are twofold:
• To improve intervention design and management, and
• To inform decisions about future investment and scale-up by establishing evidence of the results and impact of the intervention.
These overall objectives are further broken down into specific objectives:
• Assess whether interventions were implemented according to the work plan and measure the strength of the implementation.
• Examine district health governance and management capacity.
• Identify key lessons learned and provide actionable and evidence-based recommendations for improvements and scale-up.

Uganda 2020-11-23 2023-11-23 Social Science and Humanities Non-degree Award
DOROTHY NAKIMBUGWE NAKIMBUGWE
ID:
Impact of COVID19 lock down and, effectiveness of supplementary feeding on the nutrition status of mothers and their malnourished breastfeeding children, attending nutrition Units of health facilities in Kampala and Wakiso – a pilot study to inform national and organizational policies and interventions
REFNo: HS984ES

a) Assess the impact of the COVID19 lockdown and social distancing requirements on the nutrition status of mothers of children attending nutrition clinics at health centers and their access to food in Kampala and Wakiso districts through individual interviews using a semi-structured questionnaire.
b) Determine the effectiveness of a locally produced nutrient-enhanced composite porridge flour for improving the nutrition status of mothers and their breastfed malnourished children.
Uganda 2020-11-23 2023-11-23 Medical and Health Sciences Non-degree Award
DAVID KATEETE PATRICK
ID: UNCST-2020-R004018
Insight into the Role of the Microbiome in Pulmonary tuberculosis in Kampala, Uganda (MTI-Plus)
REFNo: HS738ES

The overall purpose of this proposal is to determine the composition of the microbiome in pulmonary TB patients in Kampala Uganda, and its relationship with TB treatment response and immune response relative to household healthy contacts without TB and HIV-infection. In context of treatment naïve adult TB patients, we will (1) (a) Examine the relationship between sputum and gut microbiome diversity and disease. (b) Investigate the relationship between sputum and gut microbiome composition and treatment response in patients on first-line TB therapy, and whether dysbiosis resolves in patients who get cured from TB after successfully completing anti-TB therapy. (2). Investigate the relationship between sputum and gut microbiome composition and inflammatory cytokine production capacity.
Uganda 2020-11-20 2023-11-20 Medical and Health Sciences Non-degree Award
Chioma Adeyemi Njideka
ID:
Phytochemical and Abortifacient Studies of Commelina benghalensis in Wister Rats
REFNo: SS576ES

The specific objectives of this study are;
a) To profile the phytochemical groups in C. benghalensis L in rats.
b) To determine the acute toxic dose of leaves and stalk extracts of C. benghalensis L in rats.
c) To investigate the abortifacient activities of leaves and stalk extracts of C. benghalensis L in rats.
d) To evaluate the sub-acute effect of the plant extract showing more abortifacient activity in wistar rats.

Nigeria 2020-11-20 2023-11-20 Social Science and Humanities Degree Award
Barbara Mukasa
ID:
Baseline, Midterm and End of Project Evaluation Protocol for Mildmay Mubende Region
REFNo: SS639ES

(i) Systemize baseline, midterm and end of project evaluations including interim analyses for Mubende region service delivery implementing mechanism supported by CDC Uganda.
(ii) Closely monitor the progress of outputs as measured by Monitoring Evaluation and Reporting (MER) indicators arising from implementation of activities and conduct periodic program evaluations to determine the funded activities will achieve outcomes that ultimately reduce HIV incidence and AIDS

Uganda 2020-11-20 2023-11-20 Social Science and Humanities Non-degree Award
Paul  Kutyabami
ID: UNCST-2020-R015029
Assessing the impact of the requirements for dual- licensing guidelines on the number of drug outlets and compliance to regulation
REFNo: HS1048ES

-To determine the trends in the number of pharmacies licensed as both retail and wholesale from 2016 to 2020 in NDA regions
-To establish the level of compliance of pharmacies previously dual-licensed as of 2016 to set requirements of their current license
-To explore the possible factors other than guidelines associated with a decline in the license application for pharmacies that have had dual licensure
-To determine the effect of dual licensing guidelines on access to medicines in underserved areas

Uganda 2020-11-20 2023-11-20 Medical and Health Sciences Non-degree Award
Winnifred Kansiime Kimara
ID: UNCST-2021-R012131
Predictors of indoor air quality in Kisenyi-Mugunu a slum settlement in Fort Portal Municipality, Uganda
REFNo: HS695ES

General objective
To assess predictors of indoor air quality so as to promote the health of children under five dwelling in Kisenyi-Mugunu, Fort Portal Municipality.
Specific objectives
1. To determine the level of IAQ in Kisenyi-Mugunu, Fort Portal Municipality.
2. To establish the predictors of IAQ in Kisenyi-Mugunu, Fort Portal Municipality.
3. To explore the barriers and facilitators to uptake of healthier household energy options in Kisenyi-Mugunu.

Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Jackson Orem
ID: UNCST-2021-R012016
Characterizing Determinants of Primary KSHV Infection among Children and Adolescents in Uganda
REFNo: HS735ES

1. To determine the incidence and to define the viral, immunologic, and clinical features of primary KSHV infection.
2. To identify the biologic and behavioral risk factors associated with primary KSHV infection.
3. To develop mathematical models that characterize KSHV shedding dynamics and virologic drivers required for transmission.

Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Irene Andia Biraro Rebecca
ID: UNCST-2019-R001475
Machine Learning and Secondary Data Analyses of the RASHOTS Database to Guide Clinical Decision Making and Predict Patient Prognosis at Kiruddu National Referral Hospital, Uganda
REFNo: HS745ES

The primary project objectives are:
1. To utilise ML methods to estimate the risk of mortality on the ID wards at Kiruddu National Referral Hospitals using the RASHOTS medical database
2. To develop prognosis prediction scores for survival on the ID wards using ML methods on the RASHOTS medical database based on clinical prognostic factors

The secondary project objectives are:
1. To estimate the prevalence of major mortality drivers such as tuberculosis, tetanus using the RASHOTS medical database
2. To create a prognosis prediction protocol for risk of tuberculosis related mortality as a computer application for use by clinicians on ID wards
3. To use the RASHOTS database for quality improvement in clinical care and practice in the department of Internal Medicine

Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Annette Namugaya Mugabe Jane
ID: UNCST-2020-R014795
TRENDS AND INDICATIONS FOR CAESAREAN SECTION IN MBALE REGIONAL REFERRAL HOSPITAL A CROSS SECTIONAL STUDY
REFNo: HS777ES

General Objective
To determine the trends and indications for caesarean section delivery in MRRH (Eastern Uganda) during the study period (July 2013 to June 2018)

Specific Objectives
1. To determine the trend for caesarean section in MRRH (Eastern Uganda) over the study period
2. To identify the indications for CS delivery in MRRH (Eastern Uganda) over the study period

Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Degree Award
Peter Rukundo Milton
ID: UNCST-2020-R014799
Next Generation Nutrition in Uganda: Enhancing Dietary Intake of Iron and Folic Acid in a Culturally Acceptable Food Product for Pregnant Women to Improve Maternal and Child Outcomes
REFNo: HS828ES

Evaluate the effect of the innovative product on the health outcomes of the infants at birth,Investigate the efficacy of this innovative product to reduce iron and folic acid deficiency in pregnant women.,Develop a culturally acceptable and quality assured iron bio-fortified beans and silverfish pre-cooked instant sauce fortified with iron and folic acid to meet nutritional needs for pregnancy.,
Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Irene Andia Biraro Rebecca
ID: UNCST-2019-R001475
The Trends in Clinical Presentation and Management of Diseases among Adults attending Kiruddu National Referral Hospital, Kampala: Review of Medical Records.
REFNo: HS1030ES

General objective
To analyse medical records for trends in presentation and management of disease conditions in the in-patient department (IPD) and out-patient department (OPD) at KNRH from 2019 to date.
Specific objectives
I. To describe trends of respiratory disease presentation and clinical management among adult patients presenting to the IPD, medical and general OPD at KNRH during the study period (January to July 2020) compared to the baseline period (January to July 2019)
II. To explore for any collateral effects of the global SARS-CoV-2 pandemic on chronic disease presentation and management at KNRH during the same study period.

Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Waiswa Peter
ID: UNCST-2020-R014921
AN ASSESSMENT OF THE IMPACT OF COVID-19 ON RMNCAH AND HIV SERVICE DELIVERY AND UTILIZATION IN UGANDA
REFNo: HS1084ES

1. To document the response actions for mitigating the impact of COVID-19 on RMNCAH and HIV services at national, sub-national, health facility and community levels
2. To assess the district, health facility and community preparedness to provide RMNCAH and HIV services during the pandemic.
3. To obtain information on the implications of COVID-19 on the level of access and utilization of routine RMNCAH, HIV and other health services
4. To explore the effects of COVID-19 pandemic on mental health, intimate partner violence and gender roles
5. To assess the effects of COVID-19 on early child development, food security, feeding practices and nutrition among children under five years.
6. To generate recommendations for informing future national policy and public health response to health emergencies

Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Bonnie Fournier
ID: UNCST-2019-R000250
Reducing HIV-related Stigma in School Children
REFNo: HS510ES

Specific research objectives:
● Objective 1: To assess the magnitude of change, among young people who receive the arts-based intervention, in measures of stigma (i.e., enacted, internal, anticipated, courtesy, and perceived), HIV knowledge and attitudes towards young people who are HIV+ and –affected;
● Objective 2: To assess the intervention effect on HIV testing behavior among HIV-negative sexually-active young people;
● Objective 3: To assess the intervention effect on linkage to care, initiation of Antiretroviral Therapy (ART), and adherence to ART among HIV+ young people;
● Objective 4: To evaluate how, and under what circumstances, the intervention had an effect.

Canada 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Imelda Bates
ID:
Development of a complex quality improvement intervention for timely blood transfusions for the management of postpartum haemorrhage (PPH) in Uganda
REFNo: HS579ES

1. To map out active transfusing facilities and blood centres in two districts in Uganda and create a profile of baseline measures of quality of PPH management and blood transfusion services (e.g. availability of blood, safety of blood, timeliness of referrals of women with PPH, regular measurement of haemoglobin in PPH patients) for each district
2. To determine key barriers to the appropriate management of PPH, including blood transfusion
3. To gain stakeholder buy-in and contribution to a lead-on quality improvement intervention’s design from all levels, with a specific view to feasibility and sustainability
UK 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Alison Elliott
ID: UNCST-2023-R006524
“Establishing a Single-Sex Controlled Human Schistosoma mansoni Infection Model for Uganda: Safety and Dose Finding” (CHI-S-Ug1)
REFNo: HS697ES

Primary objective: To investigate (1) the safety and tolerability and (2) the infectivity of male Schistosoma mansoni (Sm) cercariae in healthy adult Ugandan volunteers with (a) minimal prior exposure to Sm, and (b) intense prior exposure to Sm.
Exploratory objectives: To investigate the kinetics of controlled infection with male Schistosoma mansoni cercariae in healthy adult Ugandan volunteers (a) with minimal prior exposure to Sm, and (b) with intense prior exposure to Sm. To investigate immunological, metabolic and microbiome changes after infection with Schistosoma mansoni male cercariae. To investigate volunteer and wider community understandings of CHI in the context of CHI-S.


UK 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Adegbola Tololupe Adesogan Carola
ID:
FEED THE FUTURE PESTE DES PETITS RUMINANTS VACCINE ASSOCIATE AWARD
REFNo: A77ES

In the course of the pilots, the project will conduct: • A rapid assessment of existing information and surveillance activities to identify the most relevant actions to reinforce surveillance and epidemiological assessments capacity and information. • At least one training workshop to enhance skills and establish epidemiological monitoring systems that meet both disease control and project applied research needs. • Targeted sero-sampling designed for the estimation of the basic reproductive number. • Participation in the investigation of outbreaks and facilitation of the collection of material for viral isolation and genomic analysis. • Mapping of virus flows and modeling of disease transmission as an approach to integrating data from diverse sources. • Areas targeted will be points of high virus circulation and will have substantial levels of PPR antibody; the project will measure the impact of vaccination on herd immunity and the frequency of disease events.
USA 2020-11-17 2023-11-17 Agricultural Sciences Non-degree Award
John  Ssempebwa
ID: UNCST-2020-R014966
ASSESSMENT OF STATUS AND DEVELOPMENT OF FRAMEWORK AND GUIDELINES TO IMPROVE HEALTH AND SAFETY OF SWIMMING POOLS IN THE GREATER KAMPALA METROPOLITAN AREA, UGANDA
REFNo: HS730ES

Objectives
1. To determine the physio-chemical and microbiological quality of water in swimming pools.
2. To determine the knowledge, and practices of swimmers and operators regarding safety of
swimming pools.
3. To establish the hygienic and safety status at the swimming pools premises.
4. To establish a framework and guidelines to regulate operation of swimming pools in Uganda.
Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
View Sort By:

"A prosperous Science and Technology Led Ugandan Society."