Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
Search By Approval Date:
Clear Filter Total: 5,299
Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Esther Buregyeya
ID: UNCST-2020-R014116
Promoting hand hygiene through use of locally-produced alcohol based handrub in health facilities in Wakiso District-Uganda
REFNo: HS817ES

i) To develop a behavioral intervention to foster hand hygiene compliance using locally produced alcohol handrub in HCFs in Uganda.
ii) To assess the acceptability, feasibility and effect of locally-produced alcohol handrub on HH compliance among health care workers in primary health care facilities, Uganda.
(ii) To assess the cost of fostering HH through use of locally-produced
alcohol-based hand-rub.

Uganda 2020-11-26 2023-11-26 Medical and Health Sciences Non-degree Award
PAUL MBAGO
ID:
Bovine mastitis on selected farms in Kamwenge District: Prevalence and antibiograms of the associated bacteria
REFNo: A86ES

To determine the prevalence of bovine mastitis, antibiograms of associated bacteria and investigate presence of MecA and TetM resistance genes on selected farms in Kamwenge District.
Uganda 2020-11-26 2023-11-26 Agricultural Sciences Degree Award
Agabirwe Patience
ID:
INFORMATION PRACTICES OF STUDENTS WITH VISUAL IMPAIRMENT IN PUBLIC UNIVERSITY LIBRARIES IN UGANDA USING DIGITAL INFORMATION RESOURCES
REFNo: SIR49ES

To explore the information practices of students with visual impairment (SWVI) as they seek, access and use Digital information resources (DIRs) in public University libraries and therefore propose strategies to improve the utilization of DIRs by SWVI in University libraries of Uganda.
Uganda 2020-11-26 2023-11-26 Engineering and Technology Degree Award
Lina Sara Mathew Alonga Sara Mathew
ID:
Safety Profiling of Traditional Antimalaria Plant, Aristolochia bracteolata Lam. Commonly used among Communities of Jubek State, South Sudan
REFNo: HS851ES

i. To document the preparation methods, uses and effects of A. bracteolata antimalarial plant among the communities in Jubek State,
ii. To identify and quantify the levels of aristolochic acid in A. bracteolata and in preparation as used by the communities in South Sudan,
iii. To determine the general toxicity and nephrotoxicity of A. bracteolata community preparation using Laboratory animal models

South Sudan 2020-11-26 2023-11-26 Medical and Health Sciences Degree Award
owino ambrose
ID:
“Exploration of mathematics teachers’ pedagogical content knowledge for teaching subtraction strategy: A case study in Kwania District, Uganda”
REFNo: SS554ES

The purpose of this study is to explore mathematics teachers’ pedagogical content knowledge for teaching subtraction strategies.
Uganda 2020-11-26 2023-11-26 Social Science and Humanities Degree Award
Richard Mugambe Kibirango
ID:
The impact of an mhealth and environmental cues intervention on hand hygiene practice among healthcare workers in the greater Kampala metropolitan area. A cluster randomised trial.
REFNo: HS882ES

1. To explore the opportunities for enhancing healthcare workers’ hand hygiene practices in HCFs in the GKMA.
2. To explore the barriers for enhancing healthcare workers’ hand hygiene practices in HCFs in the GKMA.
3. To compare the impact of mobile phone WASH text messages with that of environmental cues on hand hygiene practice among health workers in HCFs in the GKMA.

Uganda 2020-11-26 2023-11-26 Medical and Health Sciences Non-degree Award
Emma Ariyo S
ID:
Examination of Sociocultural Boundaries and Gender construction in Women’s Rugby in Uganda
REFNo: SS579ES

1. Contributing to the body of literature on women rugby players’ use of sport to navigate socio-cultural structures in society.

2. Providing an in-depth understanding of how female participation in sport impacts multiple identities [relations] and relationships [social positioning] in reference to young women and their families and communities.

3. Inform educators, activists, policy makers and sport administrators’ decisions about developing sport opportunities for women in Uganda.
Uganda 2020-11-26 2023-11-26 Social Science and Humanities Degree Award
Edith Akankwasa
ID:
Implementing a child disability prevention, detection and rehabilitation project in central Uganda: Learning and experiences from the field
REFNo: HS896ES

i. To establish if amongst the intervention districts, those districts that show stronger implementation of birth defect and child disability prevention, child disability detection, management and rehabilitation interventions as envisaged perform better on key birth defect detection and child disability rehabilitation indicators compared to those intervention districts with “a lower level of implementation” (i.e., evidence of “dose-response”).
ii. To determine if, after three years, districts in project overall intervention area will show more improvement in coverage from baseline on key birth defect and child disability prevention, disability detection, management and rehabilitation indicators compared with those districts in the comparison area.
iii. To appraise the processes used in enhancing the delivery of the birth defect and child disability prevention, detection and rehabilitation services where they are being implemented.
iv. To explain in detail how and why the strategies employed led to the observed coverage in access to and utilization of the CDR project services in the implementation districts.
v. To characterize the stakeholders for birth defect and child disability prevention, detection and rehabilitation services.
vi. To document the barriers and facilitators used in the implementation of the CDR project along with how the barriers can be addressed

Uganda 2020-11-26 2023-11-26 Medical and Health Sciences Non-degree Award
WINTERS MUTTAMBA
ID:
Exacerbation of Chronic Bronchial Sepsis (ECBS): A study of the role of key bacteria in exacerbations of COPD and bronchiectasis
REFNo: HS921ES

SECONDARY OBJECTIVES
i. To compare bacterial loads at presentation with time to first exacerbation.
ii. To assess the relationship of bacterial loads of specific bacteria with emergency attendance.
iii. To compare bacterial loads at presentation with time-to-clinical-stability (TCS), CRP response and length of antibiotics.
iv. To assess the relationship of specific bacterial loads with quality of life (QoL) scores.
v. To assess the microbiome dynamics during- and after- treatment.

EXPLORATORY OBJECTIVES
1. To compare bacterial loads with Bronchiectasis Severity Index (BSI) in those with a clinical diagnosis of bronchiectasis.
2. To compare admission bacterial loads with baseline FEV for relationship with key clinical outcomes.
3. To compare key clinical outcomes based upon initial counts of neutrophils, lymphocytes, platelets and eosinophils, and their ratios (including principally neutrophil-lymphocyte ratio, NLR, and platelet-lymphocyte ratio, PLR).
4. To compare bacterial loads with bronchiectasis severity index (BSI) in those with a clinical diagnosis of bronchiectasis.


Uganda 2020-11-26 2023-11-26 Medical and Health Sciences Non-degree Award
Elizeus Rutebemberwa
ID: UNCST-2022-R009070
Reducing Tobacco use among the In- and Out-of-School youths in Moroto district, Uganda
REFNo: HS1021ES

General objective:
The general objective is to assess tobacco use among the youth in Moroto district.

Specific objectives:
1)Explore perceptions of tobacco use among youth in and out of school in Moroto district

2)Determine the factors associated with tobacco use among youth in and out of school in Moroto district

3)Describe the perceptions regarding tobacco use among the school teachers and administrators

4)Explore the cultural role that tobacco use plays in the lives of the youth in Moroto district.

5)Assess adherence to the tobacco control Act within bars and restaurants in Moroto district.

6)Assess youth access to tobacco in Moroto district.

7)Describe the perception of the implementation of tobacco control activities in Moroto district by enforcement officers.

Uganda 2020-11-26 2023-11-26 Medical and Health Sciences Non-degree Award
Shaheen Memon Mohamed Zahiruddin
ID:
APPLICATION OF MACHINE LEARNING TECHNIQUES TO ANTENATAL ATTENDANCE, MATERNAL MORBIDITY AND FETAL OUTCOMES IN UGANDA
REFNo: HS977ES

1. Establish the factors associated with the number of ANC visits by a pregnant woman who experiences SMM in Uganda.
2. Examine the factors associated with severe maternal morbidity as experienced by pregnant women in Uganda.
3. Assess the maternal factors associated with negative fetal outcomes in Uganda.

Kenya 2020-11-26 2023-11-26 Medical and Health Sciences Degree Award
Harriet Opondo
ID: UNCST-2022-R010927
Counselors’ Experiences of HIV Status Disclosure to Children living with HIV in Uganda
REFNo: SS626ES

-To explore subjective experiences of counselors during the process of status disclosure to children living with HIV
-To find out how counselors are prepared and trained to conduct status disclosure to children living with HIV.
-To establish the current interventions used by counselors in HIV disclosure process to children.
-To find out self-identified training needs of counselors during and after status disclosure to children living with HIV.

Uganda 2020-11-26 2023-11-26 Social Science and Humanities Degree Award
Fred Ssewamala
ID: UNCST-2020-R014060
Suubi4Stigma: Addressing HIV-Associated Stigma Among Adolescents
REFNo: SS632ES

Suubi4Stigma will address the urgent need for theoretically and empirically informed interventions that seek to reduce HIV/AIDS-associated stigma and its negative impact on child health and psychosocial well-being. Specifically, the proposed study will examine two evidence-based interventions used in mental health settings, schools, and communities: 1) group cognitive behavior therapy (G-CBT) focused on cognitive restructuring and strengthening coping skills at the individual level; and 2) a multiple family group (MFG) intervention that strengthens family relationships to address stigma among CLWH and their families.

Aim 1: Pilot test the feasibility, acceptability, and preliminary impact of innovative G-CBT and MFG on reducing HIV/AIDS-associated (internalized and family-level) stigma and its’ impact on youth and family-level outcomes (stigma, trauma symptoms, depression, sexual risk, family/social support and adherence to medication) compared to: 1a) usual care vs G-CBT; b) Usual care vs MFG; c) G-CBT vs. MFG;

Aim 2: Qualitatively examine participants’ and facilitators’ intervention experiences and identify individual, family and institutional-level facilitators and barriers to G-CBT and MFG intervention implementation and participation.

Uganda 2020-11-26 2023-11-26 Social Science and Humanities Non-degree Award
Joseph Oloro
ID: UNCST-2024-R004525
Toxicological study of the antimalarial remedy (Artavol®) and its flavonoid isolate from artemesia annua
REFNo: HS540ES

To determine acute toxicity of Artavol® and of its isolated flavonoids
ii. To investigate the sub-acute and sub-chronic toxicity potential of Artavol® and of its isolated flavonoids.
iii. To evaluate the effects of Artavol® and of its isolated flavonoids on the fetus.
iv. To examine the mutagenic potential of Artavol® and of its isolated flavonoids.

Uganda 2020-11-25 2023-11-25 Medical and Health Sciences Degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
Characteristics of persons screened, tested and diagnosed with corona virus disease-19 at health facilities in Uganda
REFNo: HS657ES

Main objective:
To estimate the cumulative incidence of a composite treatment outcome of admission to intensive care unit, mechanical ventilation or death among COVID-19 confirmed patients attending health facilities in Uganda for COVID-19 care.

Secondary objectives:
1. To describe the socio-demographic, behavioral and clinical characteristics of patients screened for and or receiving COVID-19 care at health facilities in Uganda
2. To determine the screening and testing outcomes of COVID-19 infections among patients at health facilities in Uganda

Uganda 2020-11-25 2023-11-25 Medical and Health Sciences Non-degree Award
Jafesi Pulle
ID: UNCST-2020-R014213
DECENTRALIZATION OF BENZATHINE PENICILLIN G BEST PRACTICES: BUILDING THE TOOLS FOR A SUSTAINABLE AND SCALABLE PROGRAM
REFNo: HS835ES

(1) Develop materials that can be used across Uganda and East Africa to strengthen BPG administration skills in the health worker community,
(2) Test this package of materials in Lira and Mbarara, areas with high BPG demands, and
(3) Evaluate the immediate and 3-month results of the educational program on proper BPG delivery, health worker comfort, and patient satisfaction.

Uganda 2020-11-25 2023-11-25 Medical and Health Sciences Degree Award
Firminus  Mugumya
ID:
Measuring the Impact and Sustainability of a Community-Based Child Protection Approach in Prevention of Violence Against Children in a Post Conflict Setting in Northern Uganda.
REFNo: SS566ES

The overall question for this evaluation is: What is the impact and sustainability of interventions to strengthen community-based child protection systems on prevention of violence against children in families and communities emerging from a protracted armed conflict?

The specific questions are:
•Does training Child Protection stakeholders result into functional community-based Child Protection systems for prevention of violence against children?
•Does an equipping child protection structure with knowledge, skills, financial and material resources on case management improve access to child protection services?
•Does legislation and dissemination of relevant child protection laws lead to improved implementation and enforcement for prevention of violence against children?
•Does equipping children with knowledge and skills in child protection, make them indispensable change agents for addressing violence against children?
•What evidence exists to show that the project interventions to prevent violence against children at family and community level in post-conflict setting will be sustainable?
•What are the critical enablers of project success, and what should be avoided for future similar interventions in and out of post-conflict settings?
•How sustainable are interventions interventions to strengthen community-based child protection systems?

Uganda 2020-11-25 2023-11-25 Social Science and Humanities Non-degree Award
Ronald Mulondo Mulondo
ID:
Spatiotempoaral Characterization of Congenital Myelomeningocele in Uganda
REFNo: HS763ES

1.To provide a basic description of the MMC dataset at CURE Hospital, characterizing the geographical and temporal distribution.
2.To examine whether the incidence of MMC in Uganda is non-uniform or not.
3.To examine the association between MMC case incidence and rainfall.

Uganda 2020-11-24 2023-11-24 Medical and Health Sciences Degree Award
Benjamin Atwine
ID:
Knowledge and risk factors of Hepatitis B disease among women attending Antenantal Care ate Arua Regional Referral Hospital, Uganda.
REFNo: HS785ES

General Objective
To determine the level of available knowledge and risk factors associated with Hepatitis B disease among pregnant women attending ANC at ARRH.
Specific Objective
1. To determine the percentage of women attending ANC at ARRH who are knowledgeable about Hepatitis B disease.
2. To determine the prevalence of Hepatitis B disease among pregnant women attending ANC at ARRH who take part in the study.
3. To determine the risk factors of Hepatitis B disease among pregnant women seeking ANC at ARRH.
Uganda 2020-11-24 2023-11-24 Medical and Health Sciences Degree Award
Kenneth Ssebambulidde Ssebambulidde
ID: UNCST-2021-R013976
Collection of control DNA samples for the AMBITION-cm host-susceptibility to cryptococcal infection sub-study (a genome wide association study). A sub-study of the AMBITION-cm Trial
REFNo: HS789ES

To identify genetic variants associated with Cryptococcal meningitis susceptibility and disease severity
Uganda 2020-11-24 2023-11-24 Medical and Health Sciences Non-degree Award
View Sort By:

"A prosperous Science and Technology Led Ugandan Society."