Cissy Kityo
ID: UNCST-2021-R013663
|
A Phase 3b, Randomized, Multicentre, Open-Label Study Evaluating the Efficacy, Safety, and Tolerability of Switching to Long-Acting Cabotegravir Plus Long-Acting Rilpivirine From Current Antiretroviral Regimen in HIV-1 Infected, Virological Suppressed Adults in Sub-Saharan Africa. (Cabotegravir And Rilpivirine: Efficacy and Safety Study: The CARES Study)
REFNo: HS1117ES
1.To demonstrate the non-inferior antiviral
activity of switching to IM RPV LA+CAB
LA administered every 2 months compared
with continuation of cART administered
daily over 12 months in HIV-1 infected
participants in a resource limited setting.
2.To demonstrate the antiviral and
immunologic activity of switching to IM
RPV LA+CAB LA every 2 months
compared to continuation of cART over 12
and 24 months of follow-up
3.To evaluate the safety and tolerability of
switching to RPV LA+CAB LA every 2
months compared to continuation of cART.
4.To assess viral resistance in participants
experiencing protocol-defined confirmed
virologic failure (plasma HIV-1 RNA ≥200
c/mL).
5.To assess the incidence of on-treatment
genotypic resistance to CAB, RPV and
other on-study cART up to Month 12 and
24.
|
Uganda |
2021-02-24 |
2024-02-24 |
Medical and Health Sciences |
|
Non-degree Award |
|
Joaniter Nankabirwa Immaculate
ID: UNCST-2021-R012896
|
Evaluation of the household-level impact of a single round of intermittent preventive treatment of malaria in schoolchildren: A randomized study
REFNo: HS1123ES
1. To determine the impact of intermittent preventive treatment of malaria in schoolchildren on malaria transmission at the household, as measured by the prevalence of parasitaemia at the household level.
2.To determine the impact of intermittent preventive treatment of malaria in schoolchildren on the health of the children as measured by the prevalence of parasitaemia among the children.
|
Uganda |
2021-02-24 |
2024-02-24 |
Medical and Health Sciences |
|
Non-degree Award |
|
Cathy Green Louise
ID:
|
An Investigation into the Impact on Social Inclusion of High Volume Transport (HVT) Corridors and Potential Solutions to Identifying and Preventing Human Trafficking
REFNo: SS704ES
1. To investigate the role played by HVT corridors in human trafficking in Uganda and Tanzania;
2. To explore some of the factors (primarily transport-related and regulatory) that are contributing to human trafficking along HVT corridors (roads);
3. To assess the level of awareness of human trafficking and its impacts among transport providers, the users of HVT corridors, and the communities through which these routes pass;
4. To identify and recommend pilot innovations that can help recognise and counter human trafficking along HVT corridors.
|
UK |
2021-02-24 |
2024-02-24 |
Social Science and Humanities |
|
Non-degree Award |
|
Beatrice Achan
ID:
|
Epidemiology of Invasive Fungal Diseases in Uganda
REFNo: HS1127ES
1. Estimate the prevalence of fungemia due to Candida, Cryptococcus and Aspergillus species.
2. Describe the host and environmental factors associated with fungemia.
3. Determine the antifungal resistance profiles of the isolated fungal pathogens.
4. Determine the molecular ecology of Cryptococcus species causing cryptococcal meningitis.
5. Estimate the prevalence of mycetoma in Uganda.
|
Uganda |
2021-02-24 |
2024-02-24 |
Medical and Health Sciences |
|
Non-degree Award |
|
Noble Banadda
ID:
|
Unlocking resilience benefits from African water resources (RESBEN)
REFNo: A112ES
1. To establish and develop the ARUA Water CoE as an effective, high performance, research hub & nodes network of African researchers & post graduate students
2.To establish a common intellectual grounding and poastgraduate supervision capabilities in complex social ecological systems and transdisciplinarity
3. To recognise the primary and secondary research strength
4. To locate the primary and secondary research strengths in relation to the SDGs
|
Uganda |
2021-02-24 |
2024-02-24 |
Agricultural Sciences |
|
Non-degree Award |
|
Christine Wiltshire Sekaggya
ID: UNCST-2019-R000578
|
A phase II trial to describe the pharmacokinetics, safety and efficacy of pharmacogenetics-guided dosing of isoniazid in patients with HIV-associated TB
REFNo: HS1159ES
• To describe the pharmacokinetics of isoniazid, given at a higher dose (10mg/kg) among patients with fast or intermediate NAT2 acetylator status and a standard dose (5mg/kg) among patients with slow NAT2 acetylator status, among patients with HIV and drug sensitive TB.
• To investigate the safety of pharmacogenetically-determined isoniazid dosing among TB-HIV co-infected patients with drug sensitive TB.
• To explore the efficacy of isoniazid among TB-HIV co-infected patients with drug sensitive TB receiving pharmacogenetically-determined dosing, using pharmacokinetic – pharmacodynamic (PK-PD) models.
|
Uganda |
2021-02-24 |
2024-02-24 |
Medical and Health Sciences |
|
Non-degree Award |
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Olive Kobusingye Chifefe
ID:
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Observational Studies on Helmet Use, Speeding, Seat-Belt and Child Restraint in Kampala, Uganda
REFNo: HS1178ES
Main objective:
To establish the prevalence of road traffic crash severity risk factors in Kampala city namely speed, use of helmet use, seat-belt use, and drink- driving to generate evidence that can be used to inform policy and implementation strategies to promote road safety.
Specific objectives:
1. To assess the prevalence of seat-belt use and child restraint use among car occupants in Kampala.
2. To determine the prevalence of helmet use among motorcyclists in Kampala
3. To establish the prevalence and extent of speeding in Kampala
4. To determine the level of drink-driving in Kampala
|
Uganda |
2021-02-24 |
2024-02-24 |
Medical and Health Sciences |
|
Non-degree Award |
|
Karugahe Wilber
ID:
|
Identifying psychosocial impact of COVID-19 and promising practices for meeting the mental health and protection needs to SGBV of vulnerable populations during a protracted crisis in Kampala Slums
REFNo: SS721ES
1. Identification of psychosocial and mental health issues/problems for potential SGBV victims as a result of COVID-19 pandemic.
2. To examine the relationship that exists between psychosocial and mental health issues, Sexual Gender based violence and Coping strategies among potential SGBV victims.
3. Identify the coping strategies to help potential SGBV victims to improve their mental health, avoid prevent its occurrence or re-occurrence.
|
Uganda |
2021-02-24 |
2024-02-24 |
Social Science and Humanities |
|
Non-degree Award |
|
Mohammed Lamorde
ID: UNCST-2019-R001293
|
COVID-19 in people living with HIV: Evaluation of risk factors and outcomes in resource-limited settings
REFNo: HS1192ES
To characterize the clinical features and course of symptomatic COVID-19 in PLWH, described overall and by HIV and comorbid disease factors including pregnancy status
|
Nigeria |
2021-02-24 |
2024-02-24 |
Medical and Health Sciences |
|
Non-degree Award |
|
Dorothy Nalweyiso Irene
ID:
|
Enhancing Ugandan undergraduate healthcare students’ application of evidence into practice through the development and evaluation of an Evidence-Based Practice Education Package
REFNo: HS1246ES
The main objective of the study is to determine the impact of an Evidence Based Practice (EBP) educational Package on the knowledge, skills, attitudes and behavior among undergraduate healthcare students in Uganda.
Specific objectives of the study:
i) To assess of the current literature regarding the present approaches for teaching EBP among undergraduate healthcare students.
ii) To explore the views and experiences of lecturers regarding the training and use of EBP in health practice.
iii) To assess the perceived knowledge, skills, attitudes and behaviour of EBP among undergraduate healthcare students before implementation the educational package.
iv) To develop an Evidence Based Practice (EBP) educational package for Ugandan undergraduate health care professionals.
v) To implement an Evidence Based Practice educational package among undergraduate healthcare students at Makerere university college of health sciences
vi) To compare the perceived knowledge, skills, attitudes and behaviour of EBP among undergraduate healthcare professional students before and after implementation of the educational package
|
Uganda |
2021-02-24 |
2024-02-24 |
Medical and Health Sciences |
|
Degree Award |
|
Cissy Kityo
ID: UNCST-2021-R013663
|
Ankle-Brachial Index Screening for Peripheral Artery Disease in Uganda: Building a Training Model and Exploring the Feasibility and Acceptability of Implementation Strategies, Version Date: September 30, 2020
REFNo: HS1028ES
General Objective;
The long-term goal of the project will be to provide insights into the barriers and facilitators of implementing PAD screening interventions in resource-poor settings. Early detection of subclinical cardiovascular disease—including PAD—may be a personalized and cost-effective way to reduce cardiovascular disease burden in low- and middle-income countries worldwide.
Specific aims;
-Assess knowledge of cardiovascular risk and subclinical disease
-Estimate the percentage of participants achieving competency in ABI screening techniques after receiving basic training
-Determine the perceived acceptability and feasibility of a PAD screening implementation strategy within the community
|
Uganda |
2021-02-22 |
2024-02-22 |
Medical and Health Sciences |
|
Non-degree Award |
|
Obed Mugisha
ID:
|
USING REDUCED DOSES OF INTRAVENOUS NEOSTIGMINE/GLYCOPYRROLATE TO REDUCE ITS SIDE EFFECTS IN THE MANAGEMENT OF POST-DURAL PUNCTURE HEADACHE AT MBARARA REGIONAL REFERRAL HOSPITAL: A SINGLE-BLIND RANDOMIZED DOSE-FINDING STUDY
REFNo: HS1075ES
General Objective
To assess the role of Neostigmine/Glycopyrrolate combination dose reduction on the incidence of its associated side effects in the management of PDPH in obstetric post-operative patients at Mbarara Regional Referral Hospital.
Specific Objectives
1. To compare pain scores for PDPH in the three Neostigmine treatment groups (20, 10, and 5mcg/kg).
2. To compare the incidence of Neostigmine/Glycopyrrolate side effects in the standard dose group (20mcg/kg) with the reduced dose groups(10mcg/kg and 5mcg/kg).
|
Uganda |
2021-02-22 |
2024-02-22 |
Medical and Health Sciences |
|
Degree Award |
|
Immaculate Atukunda
ID: UNCST-2021-R013573
|
WULIRA APP – OCCUPATIONAL HEARING LOSS AMONG INDUSTRIAL WORKERS IN KAMPALA, UGANDA.
REFNo: HS1237ES
1. To determine the prevalence of occupational hearing loss among workers in a steel and iron manufacturing industry in Kampala.
2. To assess the acceptability of using the Wulira App for hearing loss screening among workers in a steel and iron manufacturing industry.
|
Uganda |
2021-02-22 |
2024-02-22 |
Medical and Health Sciences |
|
Non-degree Award |
|
Joweria Nambooze
ID: UNCST-2019-R001118
|
BASELINE ASSESSMENT FOR NUTRITION INTERVENTIONS IN PALORINYA REFUGEE SETTLEMENT, OBONGI DISTRICT
REFNo: HS1241ES
The overall aim of this baseline study will be to assess the current status of nutrition outcomes, infant and young child feeding (IYCF) and livelihoods indicators among children and WRA, household food security and selected livelihood indicators among refugee households in Palorinya Refugee Settlement.
|
Uganda |
2021-02-22 |
2024-02-22 |
Medical and Health Sciences |
|
Non-degree Award |
|
Tim Colbourn
ID:
|
How does a multi-country, multilateral network focused on specific health care improvements evolve and what shapes its ability to achieve its goals?
REFNo: SS659ES
1. To characterise how the QCN initiative was conceptualized and brought together, explore its aims and ethos and understand the global context in which QED arose
2. To explore how the QCN is enacted as a strategy for linking global and national actors
3. To explore case study countries’ contexts and capacities, their interactions with the global QCN and the effects this has on the emergence of the national QCN programme
4. To characterise strategies adopted in countries, their scale, scope and focus, mechanisms of action, the evolution of programmes and what influences them
5. To map the activities of the national programmes at district level and examine the approach to intervention
6. To examine which key data are collected to evaluate the effect of the QCN and assess any effects of network activities
|
UK |
2021-02-18 |
2024-02-18 |
Social Science and Humanities |
|
Non-degree Award |
|
Charles Drago Kato Drago
ID: UNCST-2021-R012897
|
Establishment of a Biomarker research facility to first track the development of COVID19 novel diagnostics and treatment alternatives in Uganda
REFNo: HS1096ES
1. To establish a biomarker research facility at Makerere University. (Here we shall add more equipment capacity to the existing BSL3 lab at COVAB to execute COVID19 research).
2. To identify and evaluate key SARS-CoV-2 biomarkers in saliva, urine and blood with diagnostic/prognostic or therapeutic potential.
3. To develop biomarker panels (single or multiple analytes) with diagnostic/prognostic or therapeutic potential.
|
Uganda |
2021-02-18 |
2024-02-18 |
Medical and Health Sciences |
|
Non-degree Award |
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|
Robert Ssekitoleko
ID: UNCST-2019-R001716
|
Mobile Phone enabled Diagnostics for Infectious Disease Diagnosis: Low Cost Tools for Digital Health in Uganda
REFNo: SIR50ES
I. Understanding Digital Health for Infectious Disease in Low Resource Settings
II. Understanding Data Integrity and Security in Digital Health in Africa;
III. Exploring the Relationship between Data and Healthcare Policy;
IV. ICT Devices for Data Acquisition and Communication in East Africa with a focus on Uganda;
V. Capacity Strengthening - Educational Training underpinning Mobile Health.
|
Uganda |
2021-02-18 |
2024-02-18 |
Engineering and Technology |
|
Non-degree Award |
|
Christine Aanyu
ID:
|
Alarm and response systems for addressing maternal and perinatal deaths in Eastern Uganda. A case of re-activation of MPDSR
REFNo: HS635ES
1) To explore the factors that facilitate or constrain the implementation of the MPDSR protocols
2) To develop a collaborative innovation to address the constraints of implementing MPDSR protocols
3) To enhance system wide learning through documenting and sharing of best practices for implementing MPDSR protocols
|
Uganda |
2021-02-17 |
2024-02-17 |
Medical and Health Sciences |
|
Non-degree Award |
|
Peter Olupot-Olupot
ID:
|
Paracetamol for Acute Renal Injury in Severe Malaria Trial (PARIST)
REFNo: HS965ES
1. To conduct pharmacokinetic studies of paracetamol in patients with acute kidney injury in severe malaria.
2. To assess the feasibility of conducting AKI in severe malaria in Eastern Uganda.
3. To conduct safety and preliminary effectiveness study for use of paracetamol in ameliorating AKI in severe malaria.
|
Uganda |
2021-02-17 |
2024-02-17 |
Medical and Health Sciences |
|
Non-degree Award |
|
Elizabeth Ekong Namukombe
ID:
|
Work-Based Learning for Baccalaureate Nurses in Uganda: Perception and Current Practice
REFNo: HS810ES
1. Explore the perception of baccalaureate nurses in Uganda on the ease of engaging in Work-based learning.
2. Explore the perception of baccalaureate nurses in Uganda on the usefulness of work-based learning.
3. Describe the current practice of Work-Based Learning among baccalaureate nurses in Uganda.
4. Determine any existing relationship between perceived usefulness and current practice of work-based learning among baccalaureate nurses in Uganda.
|
Uganda |
2021-02-15 |
2024-02-15 |
Medical and Health Sciences |
|
Degree Award |
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