Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
Search By Approval Date:
Clear Filter Total: 6,049
Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Ivan Segawa
ID: UNCST-2021-R012795
 Nurse-led PrEP Delivery for Young Women Attending Family Planning Clinics in Uganda
REFNo: HS1740ES

Aim 1: To evaluate the feasibility and acceptability of nurse-led PrEP delivery to adolescent girls and young women attending a family planning clinic in Uganda.

Aim 2: To assess PrEP persistence among adolescent girls and young women receiving nurse-delivered PrEP at a family planning clinic.

Aim 3: To compare the characteristics of adolescent girls and young women who accept with those who decline PrEP and those who persist with those who discontinue PrEP at a family planning clinic in Uganda.
 Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nixon Niyonzima
ID: UNCST-2020-R014577
 Utility of a Liquid Blood Biopsy for Non-invasive Lung Cancer Diagnosis and Biomarker Testing at Uganda Cancer Institute.
REFNo: HS1743ES

1. To compare ctDNA sequencing to standard histopathologic diagnoses of lung cancer in patients with advanced stage lung cancer at the Uganda Cancer Institute (UCI).

2. To describe the tumor-specific molecular alterations present in lung cancer specimens and ctDNA in advanced stage lung cancer patients at UCI.
 Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ouma Simple
ID: UNCST-2021-R012820
 Childhood victimization and mental disorders among adolescents of sex-working and non-sex working mothers in post-conflict Gulu city in Northern Uganda - a cross-sectional study
REFNo: HS1769ES

The main goal of this study is to provide the evidence needed by the health care programmers and policymakers to inform appropriate policies and practices on prevention, screening, and management of victimizations among adolescents in Uganda. Specifically, the following are the study objectives:
1. To determine the prevalence of childhood victimization among adolescents.
2. To examine the relationship between sociodemographic characteristics and general health and childhood victimization among adolescents.
3. To examine the relationship between maternal sex work status and childhood victimization.
4. To examine the relationship between maternal major depression and childhood victimization among adolescents.
5. To determine the prevalence of selected childhood mental disorders among adolescents.
6. To examine the relationship between exposure to childhood victimization and childhood mental disorders in post-conflict Gulu City.

Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Degree Award
Achilles Katamba
ID: UNCST-2019-R000540
 Interrupting HIV and TB Stigma in the Household during TB Contact Investigation in Uganda
REFNo: HS1788ES

This project aims to evaluate the effects of a complex intervention on household HIV stigma and uptake of HIV testing among household members undergoing TB contact investigation.
Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jonathan Izudi
ID: UNCST-2019-R000469
 Evaluating the impact of the COVID-19 pandemic restrictions on HIV care in Kampala, Uganda: a propensity-score matched and difference-in-differences analysis
REFNo: HS1709ES

Primary objective: To evaluate the impact of the COVID-19 pandemic restrictions on linkage to care, time to linkage, timely ART initiation, retention in care, viral load suppression, and mortality among people living with Human Immunodeficiency Virus (PLHIV) in the Kampala Capital City Authority (KCCA) health facilities in central Uganda

Secondary objective: To document and synthesize measures for continuity of service delivery for PLHIV during the COVID-19 pandemic
 Uganda 2021-10-12 2024-10-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Betty  Nambuusi Bukenya
ID:
Youth Wellbeing Champions: Piloting community-based, youth peer-led mental health and wellbeing support for young people in Uganda
REFNo: SS956ES

Study goal: To generate evidence around the effectiveness of a pilot community-based and responsive wellbeing / mental health intervention led by young people with lived experience of care and supported by social work practice/practitioners in Uganda. Specific objectives 1. Assess the level of knowledge and understanding of a trauma-informed approach to addressing mental health needs among social workers based on the Kirk Patrick pre-post questionnaire. 2. Assess the prevalence of clinical mental health, well-being, self-esteem/ self-worth, and depression symptoms among children and youth based on the WHO-5 / PHQ-9 and Rotter’s Locus of Control. 3. Examine the level of knowledge of mental health literacy, resilience, psychosocial support, and wellbeing practice among care leavers based on Kirk Patrick's pre-and post-assessments questionnaire.
Uganda 2021-10-12 2024-10-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Fred Ssewamala
ID: UNCST-2020-R014060
 Youth Health SMS: Using mobile technology to prevent HIV and related Youth Health problems: Sexual health, Mental health, and Substance use in southwest Uganda
REFNo: SS969ES

This study will result in the development of one of the first mobile phone-based interventions for Adolescents and Young Adults (AYA) in East Africa that begins to address the co-morbid HIV risk factors of sexual health, mental health, and alcohol use. AYA is a developmental period associated with the increased importance of peers, increased technology use, increased mobility, initiation of sex, emergence of mental health disorders (if at risk), and initiation of alcohol use. Consequently, AYA is a critical time for preventive interventions. Poor mental health and alcohol abuse are associated with increased risk for HIV infection. Thus, the proposed research will attempt to address these areas concurrently.

The proposed research will evaluate if adapting and updating the existing free and nationally available text message and interactive voice recognition (IVR) service included in *161 that was initially developed by FHI 360. Our work will test and tailor messages for AYA to disseminate pre-exposure prophylaxis (PrEP) information and pilot specific mental health and hazardous alcohol use screens. Symptomatic AYA will be referred to behavioral health counselors for further assessment and treatment as needed. AYA today rely heavily on mobile phones for information and services, thus we believe the proposed intervention could be applied and adapted across the region, and potentially in other under-resourced settings.

We will conduct formative research to evaluate and adapt an existing text-message and interactive voice recognition (IVR) platform. We will then pilot the new menus and examine if using this platform promotes HIV prevention (pre-exposure prophylaxis (PrEP), HIV testing, safer sexual behaviors) and increases mental health and alcohol use screening and linkage to counselors as needed for adolescents and young adults (AYA) in a rural Ugandan region with high HIV seroprevalence and limited resources.

2. State the study objective(s) and research question(s)
Aim 1: To adapt an evidence-based mobile phone-delivered sexual health program, to include PrEP information and deliver mental health and alcohol use assessments with the goal of increasing screening and referral, as well as linkage to counselors for AYA at HIV risk.

Aim 2: Evaluate through a pilot RCT (N=126 AYA, 15-19 years) intervention (a) acceptability and feasibility, and (b) impact on uptake of HIV prevention strategies, as well as screening and linkage to mental health and alcohol use school-based counselors.

 Uganda 2021-10-12 2024-10-12 Social Science and Humanities Clinical Trial Non-degree Award
Adeodata Rukyalekere Kekitiinwa
ID: UNCST-2019-R000799
 Mortality Surveillance Activity Protocol All-cause Mortality Surveillance in Bunyangabu, Kabarole and Kyenjojo districts, Uganda
REFNo: HS1755ES

the objective of establishing a mortality surveillance system is to enumerate and document all-cause mortality in the 3 districts of Bunyangabu, Kabarole, and Kyenjojo in Uganda. Specifically this will; a) determine HIV/AIDS related and proportionate mortality rate in the three districts, b) determine maternal and neonatal mortality rates in the three districts c) identify causes of death among HIV patients and causes of pregnancy-related deaths in the three districts and d) document the implementation process of mortality surveillance in order to inform future scale up.
 Uganda 2021-10-12 2024-10-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Waruiru Kolff Kayla Tinie
ID: UNCST-2021-R012291
 Turn-taking interactions in Eastern male Chimpanzees (Pan troglodytes schweinfurthii)
REFNo: NS295ES

Understanding the turn-taking systems of chimpanzees and how this relates to human language and it's origins. Hence, whether the turn-taking systems of chimpanzees are influenced by interpersonal contexts (social bonds & dominance rank).
 Netherlands 2021-10-12 2024-10-12 Natural Sciences Non-Clinical Trial Degree Award
ALEX NDYABAKIRA
ID:
Assessing use of SolarSack for treatment of safe drinking water in Uganda
REFNo: HS1680ES

1. To determine the willingness to buy and acceptability of SolarSack water treatment device
2. To determine the most appropriate cost per unit for SolarSack for rural, peri-urban and urban settings
3. To explore user preferences for the SolarSack device
4. To determine the effect of SolarSack use on prevalence of waterborne diseases

 Uganda 2021-10-11 2024-10-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Phyllis Kisa
ID: UNCST-2023-R007952
 SURGICAL NEONATES IN A LOW-RESOURCE SETTING: AN AUDIT OF NUTRITION AND OUTCOME
REFNo: HS1736ES

To audit our current the nutritional regime among newborns with gastro-intestinal anomalies admitted to the Paediatric Surgical Unit at Mulago National Referral Hospital(MNRH).
Uganda 2021-10-11 2024-10-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Tukwasiibwe Moses
ID:
Impact of forced displacement on labour markets in Uganda
REFNo: SS1039ES

Objective 1) Provide strong empirical evidence of the direct and indirect impacts. Against the backcloth of a comprehensive literature survey, and investigating non-camp urban refugee populations in Kampala and as well as camp based refugees in Nakivale refugee settlement in Uganda.

Objective 2) Identify the mechanism(s?) through which impacts occur. Analyzing the empirical evidence we will: i) explore direct and indirect (partial equilibrium) impacts and outcomes on the dynamics of labor market and business behavior, assessing impact-attribution and correlating variables such as labor supply and wages, capital investment/ labor trade-offs and demand side factors, productivity and skills, national and international investment patterns; ii) assess the role of political economy, regulatory and policy frameworks; iii) generate qualitative analysis of household and individual livelihood/life course experiences in relation to labor market outcomes, iv) generate local, national and comparative findings.

Objective 3) Support the development of evidence-based, effective, and context-specific jobs policy advice. The analytical outputs will provide a robust evidence base for jobs policy advice envisaged at different levels (local, national, and international), and for different stakeholders (e.g. municipal and national governments, donors, intergovernmental and non-governmental organizations, private sector investors, entrepreneurs and SME sector, and displaced and host populations). Policy advice will include, inter alia: finance and investment strategies, regulatory framework e.g. rights to work/rights at work and employer conditions for decent work), spatial planning, training and skills, role of investment incentives, socio-economic policies for displaced and host populations vis à vis labor markets.

Objective 4) Generate new data that will be in the public domain for use in further research. The proposed study will generate new statistical (survey) data sets for three of the four case countries: Colombia, Ethiopia and Uganda. In Jordan, the study team is already in possession of sufficient data through previous surveys conducted by Fafo and partners. When designing the new surveys, special attention will be given to establish robust baselines that can be applied in future impact analyses. Responding to this objective and the general TOR requirements, we shall place all the data generated in the proposed project in the public domain.

Uganda 2021-10-11 2024-10-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
PETER OMASWA
ID:
Relevance and Factors Affecting Exchange of Plant Material and Data to Conservation
REFNo: NS156ES

General Objective
To assess the importance of plant material and data exchange between African and European Institutions for conservation.

Specific Objectives
1. To review the extent to which plant material and data are exchanged between African and European institutions.

2. To evaluate the opportunities and constraints to plant material and plant data exchange between African and European Botanical Institutions.

3. To evaluate the proportion of exchanged plant material and data translated into conservation applications.


 Uganda 2021-10-08 2024-10-08 Natural Sciences Degree Award
Carolyn Nakisige
ID:
Preventing cervical cancer in HIV-infected Kenyan and Ugandan women
REFNo: HS1372ES

1. To evaluate HR-HPV DNA testing of self-collected vaginal swabs combined with VIA in screening for cervical cancer in HIV-infected women.
2. Determine if aflatoxin is a risk factor for cervical cancer among HIV-infected Kenyan and Ugandan women.
 Uganda 2021-10-08 2024-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Alice  Emasu
ID: UNCST-2021-R013920
 EXPERIENCES OF LIVING WITH OBSTETRIC FISTULA AMIDST COVID -19 PANDEMIC IN EAST AND CENTRAL UGANDA: Qualitative study.
REFNo: HS1464ES

General Objective
To document the experiences of living with fistula amidst the COVID-19 pandemic among women who developed OF during corona virus pandemic, those who had fistula and had started seeking for care, those who were repaired and were at the stage of reintegration and those declared as incurable between 15-49 years of age from Eastern and Central Uganda

Specific objectives

1) To document participant’s awareness about COVID 19 Pandemic

2) To explore the perceptions of women living with OF amidst COVID 19 Pandemic

3) To explore the effect of COVID -19 on the livelihood of women with OF.

4) To explore experience in accessing fistula services among women reintegrating and screened for surgeries during the COVID-19 pandemic.
 Uganda 2021-10-08 2024-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Scovia  Mbalinda Nalugo
ID: UNCST-2020-R014259
 Aging with HIV: Experiences and challenges of older adults 50 years and above living with HIV
REFNo: HS1759ES

3. To explore determine the challenges faced by older adults 50 years and above aging with HIV.,2. To describe the experiences of older adults 50 years and above aging with HIV.,The goal of this study is to explore the experiences, perceptions, and challenges of older adults 50 years and above aging with HIV.,
 Uganda 2021-10-08 2024-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Juma Kalyegira
ID:
The Role of Basic Psychological Needs Satisfaction for the Psychological Wellbeing and Social-Cultural integration of Refugees in Rhino Camp Refugee Settlement, Uganda
REFNo: SS905ES

• To estimate the relationship between the three psychological basic needs satisfaction (Autonomy, relatedness and competence) to the psychological wellbeing of refugees.
• To determine whether the basic psychological needs satisfaction influences refugee integration.
• To find out what factors influence the need satisfaction/frustration for refugees and how?
• To estimate whether physical and psychological need satisfaction interact in an “unprepared to benefit” or “buffering against adversity” direction?

Uganda 2021-10-08 2024-10-08 Social Science and Humanities Non-Clinical Trial Degree Award
John Byabagambi Bekiita
ID:
Ability and willingness to pay for voluntary medical male circumcision in Uganda: A mixed-methods study
REFNo: HS1523ES

1. To identify the factors that determine the ability to pay for VMMC in Uganda.
2. To determine the factors associated with willingness to pay for VMMC services in Uganda.
3. To find out the reasons that inform the choice of either the willingness to pay or not to pay for VMMC services in Uganda.

 Uganda 2021-10-08 2024-10-08 Medical and Health Sciences Non-Clinical Trial Degree Award
Julian Adong
ID: UNCST-2021-R013487
 Pandmic-related disruptions in HIV care among adolescents and young adults with HIV (AYAWHIV) and the potential for mHealth interventions.
REFNo: HS1686ES

To examine the effects of the COVID-19 restrictions on HIV treatment of AYALWHIV and assess the potential of mHealth intervention in bridging these disruptions.
 Uganda 2021-10-08 2024-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Fred Nalugoda
ID: UNCST-2021-R013343
 Transactional sex and HIV among men in Rakai, Uganda
REFNo: SS984ES

The overall goal of this research is to understand the characteristics of men who engage in transactional sex and the causal pathways that lead from transactional sex to incident HIV in Rakai, Uganda.
• Aim 1. To measure perceptions, content validity, and response processes of transactional sex measures in the Rakai Community Cohort Study
• Aim 2. To examine men’s experiences in transactional sex relationships and factors that may heighten risk for HIV

Uganda 2021-10-08 2024-10-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
View Sort By:

"A prosperous Science and Technology Led Ugandan Society."

NRIMS