Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
Search By Approval Date:
Clear Filter Total: 5,779
Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
David Musoke
ID:
Collaboration between Biomedical and Traditional Mental Health Service Providers in Wakiso District, Uganda
REFNo: HS1581ES

To explore how biomedical service providers and traditional healers can work together to improve access to mental health care in Wakiso district, Uganda.
 Uganda 2021-09-08 2024-09-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Janet SEELEY
ID:
Examining ethical issues, stakeholder engagement and acceptability of biobanking in Sub-Sahara Africa
REFNo: HS1645ES

General Objectives:
To explore perceptions, informed opinion and experiences of key stakeholders on approaches and value of community engagement in biobanking in LMIC; and if and how community approval should be obtained.

Specific Objectives:
1. To explore key stakeholders’ perceptions, informed opinions and underlying values around potential benefits of biobanks in SSA and important aspects of operationalising a biobank in LMICs.
2. To describe approaches that could be used to engage communities and stakeholders about biobanking.
3. To examine governance systems and structures that should be in place for a biobank to become operational, and ways in which community voices might be included in those systems
4. To determine initial key elements required to assume a community social license based on outputs of 1-3

UK 2021-09-08 2024-09-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Edward  Mukiibi
ID:
RESEARCH DATA MANAGEMENT PRACTICES IN SELECTED HEALTH INSTITUTES IN UGANDA
REFNo: HS1714ES

i) To describe the characteristics of research data created and held in selected Health Institutes in Uganda.

ii) To examine the research data management practices in selected Health Institutes in Uganda.

iii) To evaluate research data management readiness of selected Health Institutes in Uganda.

iv) To explain the challenges affecting adoption and uptake of RDM practices in selected Health Institutes in Uganda.

v) To propose interventions to improve RDM practices in selected Health Institutes in Uganda.

 Uganda 2021-09-08 2024-09-08 Medical and Health Sciences Non-Clinical Trial Degree Award
Zarin Machanda Machanda
ID:
The form and functions of leadership in wild chimpanzees
REFNo: NS288ES

This project will establish chimpanzees (Pan troglodytes) as a new comparative model of human-like leadership by testing how individual variation across a leader’s temperament, behaviour, and physiology shapes collective action in natural social groups. The first aim of the project is to support continuing long-term data collection by the Kibale Chimpanzee Project. We have three additional research aims that are specific to this project: (1) to identify and describe different domains of leadership in wild chimpanzees; (2) identify and describe the characteristics of chimpanzee leaders; and (3) evaluate the success of different pathways to leadership for chimpanzees. This project aims to collect both observational and experimental data that will provide detailed empirical insight into leadership among wild chimpanzees
 USA 2021-09-08 2024-09-08 Natural Sciences Non-Clinical Trial Non-degree Award
Robert Opika Opoka
ID: UNCST-2021-R014036
 An implementation toolkit for the use of hydroxyurea in the treatment of sickle cell anemia in Ugandan children
REFNo: HS1646ES

1) Assess the uptake and proper use of hydroxyurea among SCA patients at Jinja and Atutur Hospitals as a result of the implementation toolkit pilot,
 Uganda 2021-09-03 2024-09-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Walter Ojok
ID: UNCST-2021-R004415
 SYNTHESIS OF NOVEL MESOPOROUS ADSORBENTS FOR FLUORIDE REMOVAL FROM WATER
REFNo: NS158ES

(i) To study the hydrochemical characteristics of Ndali-Kasenda crater lakes used as water sources with focus on the occurrence and spatial distribution of fluoride.
(ii) To explore the possibility of synthesizing biosorbents for fluoride removal using local base materials (Phoenix reclinata seeds, cassava starch and banana extract as soft templates.
(iii) To conduct batch and column experiments on removal of fluoride using synthesized biosorbents to assess their fluoride removal performance.
(iv) To design laboratory scale pilot column filter studies for fluoride removal with high performance synthesized biosorbent for Ndali-Kasenda lake water.

Uganda 2021-09-03 2024-09-03 Natural Sciences Degree Award
Suzan van der Lee
ID:
Dry Rifting In the Albertine- Rhino Graben, Uganda (DRIAR)
REFNo: NS255ES

A geophysical, geochemical, geological, and geodynamic investigation of the Albertine-Rhino Graben in western and northwestern Uganda to improve our understanding of continental rifting in areas where volcanic activity is minimal.
Netherlands 2021-09-03 2024-09-03 Natural Sciences Non-Clinical Trial Non-degree Award
Joweria Nambooze
ID: UNCST-2019-R001118
 FOOD CHOICES AND THE FOOD ENVIRONMENT OF SMALL-HOLDER FARMERS IN MPIGI
REFNo: A146ES

Examine factors influencing maternal food choices and nutrition outcomes and understand how they interact.,Explore the internal and external food environments and how they impact food choice among rural female smallholder farmers,Determine the relationship between agricultural activities on maternal time use and food choices among rural female smallholder farmers,Determine the daily time use patterns of rural female smallholder farmers,Assess the nutritional status of rural female smallholder farmers,To examine the dynamic interactions between women’s time use and food environments and their influence on food choices and nutrition outcomes of rural smallholder female farmers living in Mpigi district,
 Uganda 2021-09-03 2024-09-03 Agricultural Sciences Non-Clinical Trial Non-degree Award
Tu Hoang Phuong
ID:
Forest succession analyses in Kitigo as a basis for close-to-nature reforestation planning
REFNo: NS279ES

To understand the details of termite-fungi relationships in the context of soil nitrogen allocation in Central African derived savanna; to clarify and classify the Nitrogen absorption strategies of various woody species/tree families, in order to develop crucial criteria for tree species selection for Nitrogen limited target sites; to work out if Nitrogen-15 of tree’s living sapwood could be an indicator for soil nitrogen availability.

 Vietnam 2021-09-03 2024-09-03 Natural Sciences Non-Clinical Trial Degree Award
Cristina Clerici
ID:
Yes, women can. The role of information and norms in encouraging women to enter male-dominated sectors in Uganda
REFNo: SS968ES

Gain insights on information available to aspiring female entrepreneurs and the constraints they face when choosing their sector of business.
 Italy 2021-09-03 2024-09-03 Social Science and Humanities Non-Clinical Trial Degree Award
Ziidah Namwaya
ID:
Exploring the use of Active Birthing Techniques for Normal Labour and Birth among Midwives working in the Metropolitan Region, Kampala-Uganda
REFNo: SS976ES

1. To evaluate the status of the environment in the three health facilities Kitebi, Komamboga and Kisugu as regards the use of active birthing techniques
2. To identify the available active birthing techniques at the health facilities
3. To assess current practice as regards the use of active birthing techniques for normal labour and birth among midwives working at the health facilities
4. To determine the level of knowledge as regards the use of active birthing techniques
5. To explore the potential factors that might influence the use of active birthing techniques for normal labour and birth among midwives working at the facilities
6. To describe the acceptability and experience of using upright positions such as hands- and-knees position, squatting, leaning forward, kneeling among pregnant women and midwives in the selected health facilities.

 Uganda 2021-09-03 2024-09-03 Social Science and Humanities Non-Clinical Trial Degree Award
Solomon Wafula Tsebeni
ID: UNCST-2021-R013883
 Assessment of indoor air quality, risk factors and potential health effects among residents in an urban informal settlement in Kampala, Uganda
REFNo: SS996ES

To describe the potential health effects associated with indoor air pollution. ,To assess the factors associated with indoor air pollution among households. ,To determine the levels of indoor PM2.5, and Carbon monoxide (CO) in households., To determine levels of indoor air pollution, its associated risk factors and potential health effects among residents in an informal settlement in Kampala so as to generate information that can be used in design appropriate strategies, policies and practices that promote good air quality in households, hence mitigate health problems associated with indoor air pollution. ,
 Uganda 2021-09-03 2024-09-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
Amy  Ritterbusch Elizabeth
ID:
Child Protection Mapping and Honour
REFNo: SS970ES

1.To examine the effect of global narratives of child wellbeing on child protection and rights practices in Uganda
2.To explore prospects for local child protection practices in informing and enriching global child protection policy
3.To explore the concept of honour and examine how it promotes children’s wellbeing and or sustains violence against children in the Ugandan context.

USA 2021-09-03 2024-09-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jesca Nantume
ID: UNCST-2021-R013984
 Knowledge, attitudes and practices towards the tobacco use control measures among teenagers aged (13-19) years; A cross sectional study in the slum areas of Kampala Uganda
REFNo: SS988ES

To evaluate knowledge, attitudes and practices towards tobacco control among teenagers
aged (13-19) years
1. To evaluate existing control measures among teenagers
2. To assess the knowledge, attitudes, and practices of the current tobacco control
measures among teenagers.
3. To evaluate the cause of initiation of tobacco use in slums among teenagers
 Uganda 2021-09-03 2024-09-03 Social Science and Humanities Non-Clinical Trial Degree Award
Danette Cagnet Lee
ID:
Community-led Total Sanitation Programming and the Maintenance of Sanitation Behaviors
REFNo: SS737ES

The purpose of this qualitative, exploratory, case study research is to better understand stakeholder's, including village community members, village leadership, and CLTS practitioner, perceptions of the facilitators and hindrances to the maintenance of sanitation in the maintenance stage of Community-led Total Sanitation programming in Uganda, East Africa. This study seeks the perspective of and participation of village community stakeholders receiving the Community-led Total Sanitation intervention implemented by the non-governmental organization, Kibo Group International.
 USA 2021-09-02 2024-09-02 Social Science and Humanities Non-Clinical Trial Degree Award
Joyce Kambugu Balagadde
ID: UNCST-2020-R014996
 Acute Leukemia Banking and Biology Study for Patients at the Uganda Cancer Institute.
REFNo: HS1590ES

1. To determine the genomic profile of patients with acute leukemia and identify the prevalence of various fusions and mutations in these patients.
2. To collect and store corresponding subjects’ medical information including diagnosis and disease characterization, laboratory and imaging studies, treatment, and outcome.

 Uganda 2021-09-02 2024-09-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
John Baptist Asiimwe
ID: UNCST-2021-R013716
 The Traditional Medicine Practitioner’s Concept of Cancer, its Care, Herbal medicine use and the Patients Perceived benefits (Clinical outcomes) in Selected Districts of Central Uganda.
REFNo: HS1602ES

1. To establish the prevalence and predictors of the use of herbal medicines’ in cancer
2. To explore the concept of cancer and its care in traditional medicine as perceived by traditional medicine practitioners (TMPs) in selected districts of central Uganda
3. To document the herbs used by traditional medicine practitioners (TMPs) to manage cancer in selected districts of central Uganda.
4. To determine the clinical outcomes in patients with cancer treated by traditional medicine practitioners (TMPs).

 Uganda 2021-09-02 2024-09-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Moses Adriko
ID: UNCST-2019-R001787
 Gaining community insights into societal causes of and solutions for schistosomiasis transmission hotspots (InSight-ScHot)
REFNo: HS1616ES

To identify non-mass administration preventative chemotherapeutic control measures for schistosomiasis that members of the community see as implementable
 Uganda 2021-09-02 2024-09-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Enock Matovu
ID:
Identification of the Genetic Markers of Trypanotolerance in Indigenous Cattle of Apach District, Northern Uganda
REFNo: NS247ES

Main Objective
To identify genetic markers of Animal African Trypanosomiasis (AAT) tolerance in indigenous cattle

Specific Objectives

i. To set up a panel of phenotypically characterized indigenous cattle with respect to AAT susceptibility

ii. To develop a data base of reference genomes and transcriptomes of indigenous cattle from an AAT endemic region of mid-northern Uganda
iii. To determine the genotypes associated with trypanotolerance in indigenous cattle

 Uganda 2021-08-31 2024-08-31 Natural Sciences Non-Clinical Trial Non-degree Award
Rhoda Wanyenze
ID: UNCST-2021-R013352
 Assessment of the Implementation Processes and Outcomes of the HIV Assisted Partner Notification Program, Ministry of Health, Uganda
REFNo: HS1671ES

3.2 General Objective
To assess the Implementation processes and outcomes of the HIV Assisted Partner Notification Program in Uganda
3.3 Study Objectives
1. To determine the current level of uptake of APN services and the factors associated with uptake of these services among HIV index clients.
2. To assess the acceptability and uptake of APN services among a sub-sample of partners of APN clients.
3. To assess the extent to which the existing service delivery environment influences the delivery of APN services.
4. To document the perceptions and experiences of users of APN services, challenges faced in utilizing APN services and concerns those users have regarding the way APN services are provided.
5. To determine the positive and negative outcomes of APN services in Uganda, and the support mechanisms available for those who experience negative outcomes.
6. To document the barriers to and facilitators of successful APN implementation and the challenges implementers face during APN implementation.
7. To document the existing opportunities that can inform the future scale-up of the APN program.

 Uganda 2021-08-31 2024-08-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Pontiano Kaleebu
ID: UNCST-2021-R013577
 A behavioural Science Research to Determine Factors that Facilitate Future Uptake of HIV Prevention Products and Multi-Purpose Prevention Technologies to Prevent HIV and Unwanted Pregnancy in Sub-Saharan Africa Universally Accessible HIV Prevention Technologies for African Girls and Young Women through Knowledge Applied from Behavioural Economics (UPTAKE)
REFNo: HS1540ES

Multi-purpose Prevention Technologies (MPTs) to prevent HIV and unwanted pregnancy in Sub-Saharan Africa

i. To understand facilitators of and barriers to uptake and retention of injectable and implantable long acting pre-exposure prophylaxis (LA-PrEP) and MPT to inform product development, using formative behavioural research methods
ii. To design interventions to impact the uptake of new biomedical HIV prevention products, as part of a suite of self-care and self-screening products for sexual and reproductive health, using quantitative behavioural research methods
iii. To test the effectiveness of the alternate design/interventions and strategies, using marketed LA contraceptive products as proxies for LA HIV prevention products in development
iv. To estimate the cost of retention interventions and the cost effectiveness of products and delivery methods among adolescent girls and young women (AGYW) and female sex workers (FSWs) for prevention of pregnancy and/or HIV, using modelling

 Uganda 2021-08-31 2024-08-31 Medical and Health Sciences Clinical Trial Non-degree Award
Emmy Okello
ID: UNCST-2020-R009792
 “Active Case Detection and Decentralized Dynamic Registry to Improve the Uptake of Rheumatic Heart Disease Secondary Prevention” (ADD-RHD)
REFNo: HS1561ES

Secondary objectives include technical proficiency, acquisition times, global image quality, and user satisfaction and confidence. Each of these parameters will be reported for the entire training group and a sub-group analysis will look for differences between curriculum groups. Acquisition times and image quality will be compared between trainees and expert sonographers.,To determine the impact of a pragmatic RHD primary prevention program in Uganda,
 Uganda 2021-08-30 2024-08-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Comfort Mukasa Hajra
ID:
Real-time access to sanitation information for improved management of sanitation services: A case Study in Kawempe division.
REFNo: HS1458ES

Main Objective:
To test if timely access to sanitation information leads to improved sanitation planning, increased access to safely managed sanitation services and improved multi-sectoral collaboration.

Specific Objectives:
1. To design and test the effectiveness of timely access to sanitation information for planning, coordination and access to improved sanitation services.
2. To validate user needs for sanitation service provision in Uganda.
3. To document scalable best practice mechanisms for improved multi-sectoral planning and coordination on sanitation.
 Uganda 2021-08-30 2024-08-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eric Awich Ochen
ID: UNCST-2021-R013266
 Preventing Gender-based Violence: Video Game Intervention Designed as an Educational Tool to Address Child Marriage in Uganda
REFNo: SS880ES

To assess the effectiveness of the game (Peace) in promoting pro-social attitude/behavior change and empathic capacity among young people to prevent violence.
• Help young people understand what sexual exploitation is and how it is linked to gender inequalities.
• Increase young people’s understanding about how adult power is misused to abuse and silence them.
• Show young people that perpetrators will seek out and exploit young women’s vulnerabilities.
• Help young people understand the impact that sexual coercion has on everyone involved.
• Empower young people in reporting incidents of child sexual abuse and sexual coercion.
• Increase awareness of the role of various agencies/individuals that can help.
• Help young people understand ways in which adults may groom them using various tactics.
• Help young people understand the relationship between sexual coercion and child marriage.
• Give young people the opportunity to develop skills, knowledge, and competencies that can help them make sound decisions for themselves or others in real life situations.
• To support and empower young people in avoiding child marriage


Uganda 2021-08-30 2024-08-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
NAMANDE MUGERWA SARAH
ID:
“EKISAAKAATE” (ROYAL ENCLOSURE) PEDAGOGY AND EARLY CHILDHOOD MORAL LEARNING OUTCOMES IN BUGANDA KINGDOM IN UGANDA
REFNo: SS975ES

To establish the mediating relationship between multiculturalism and early childhood moral learning outcomes.,To examine the relationship between “ekisaakaate” role play instruction pedagogy and early childhood moral learning outcomes.,To determine the relationship between “ekisaakaate” traditional story telling instruction pedagogy and early childhood moral learning outcomes.,To establish the relationship between “ekisaakaate” living values-based contextual instruction pedagogy and early childhood moral learning outcomes.,To find out the relationship between “ekisaakaate” native language instruction pedagogy and early childhood moral learning outcomes. ,
 Uganda 2021-08-30 2024-08-30 Social Science and Humanities Non-Clinical Trial Degree Award
Lazaaro Mujumbusi
ID: UNCST-2023-R007470
 Exploring understandings of and attitudes towards Covid-19 in Mayuge district Uganda
REFNo: SS977ES

1. To explore community members' perceptions of COVID-19 and its transmission, with a focus on ideas about responsibility.
2. To investigate how ideas about responsibility intersect with existing inequalities around occupation, tribe, and gender.
3. To examine whether, and how, understandings of COVID-19 transmission have impacted everyday WaSH practices.
4. To develop insight that may be of value to developing interventions aimed at reducing transmission and/or stigma.

Uganda 2021-08-30 2024-08-30 Social Science and Humanities Non-Clinical Trial Degree Award
Patrick  Vudriko
ID:
Survey to identify priority livestock diseases and diagnostic needs of animal health professionals and farmers in Central and Southwestern Uganda
REFNo: A84ES

Specific objectives
1. To identify the priority livestock and poultry diseases for which diagnostic services and diagnostic kits/aids are needed by various stakeholders (farmers, vets).
2. To assess the perception and attitudes of key stakeholders in the animal industry on the value and quality of existing animal diagnostic services in Uganda

 Uganda 2021-08-27 2024-08-27 Agricultural Sciences Non-degree Award
Suzanne  Kiwanuka N
ID: UNCST-2020-R014671
 Using High Impact Communication Strategies to increase blood donation awareness among secondary school students in Uganda
REFNo: SS802ES

1. To increase knowledge and awareness about blood donation among secondary school students in Uganda using targeted communication strategies.
2. To increase willingness to donate blood among secondary school students in Uganda using targeted communication strategies
3. To increase intention to donate blood among secondary school students in Uganda using targeted communication strategies

 Uganda 2021-08-27 2024-08-27 Social Science and Humanities Non-degree Award
Christine Akello Kalumera Kalumera
ID: UNCST-2021-R013514
 OPTIMISING USER INVOLVEMENT IN USER STORIES COLLECTION, ANALYSIS AND DESIGN TASKS FOR EHIS DEVELOPMENT: APPLYING COLLABORATION ENGINEERING PRINCIPLES TO HUMAN CENTRED DESIGN
REFNo: SIR62ES

The main of objective of this research is to develop a collaborative engineering process to improve user involvement in requirements gathering, analysis and design and stages of the user centred design approach, when developing electronic health information systems
 Uganda 2021-08-27 2024-08-27 Engineering and Technology Non-Clinical Trial Degree Award
Olive Kobusingye Chifefe
ID:
Assessing the impact of COVID-19 on the mobility patterns in Kampala Metropolitan Area
REFNo: HS1636ES

To explore the socio-economic impact of implementing the regulations on transportation.,To describe ways in which transporters coped with the COVID-19 related restrictions on transport. ,To identify ways in which commuters coped with the threat of COVID-19., The overall objective of this study is to examine the impact of the COVID-19 pandemic on mobility patterns in the Kampala Metropolitan area so as to inform planning transportation during the pandemic and in the post-COVID-19 period. ,
 Uganda 2021-08-27 2024-08-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
BRENDA GATI MIREMBE
ID: UNCST-2021-R013390
 A Phase 3, Randomized, Active Controlled, Double-blind Clinical Study to Evaluate the Efficacy and Safety of Oral Islatravir Once Monthly as Pre-Exposure Prophylaxis in Cisgender Women at High Risk for HIV 1 Infection.
REFNo: HS1631ES

Primary Objectives:
1. To evaluate the efficacy of oral ISL QM compared to FTC/TDF QD for the
prevention of HIV-1 infection as assessed by the incidence rate per year of confirmed
HIV-1 infection.

2. To evaluate the safety and tolerability of oral ISL QM compared to oral FTC/TDF QD as assessed by review of the accumulated safety data

Secondary Objective
1. To evaluate the efficacy of oral ISL QM in reducing the incidence per year of HIV-1
infection relative to the background rate.

 Uganda 2021-08-27 2024-08-27 Medical and Health Sciences Clinical Trial Non-degree Award
ROSCO KASUJJA
ID: UNCST-2019-R000504
 Treating Depressive Symptomatology in Congolese Refugees in Uganda and Rwanda: Adapting and Evaluating Community-based Socio-therapy
REFNo: SS263ES

1. Develop implementation guidance for adapting, delivering, supervising and monitoring aCBS for refugees across diverse settings. 2. Build research capacity for evaluating complex interventions in Rwanda and Uganda. 3. Enhancing knowledge about a scalable and inclusive form of intervention aimed at supporting the mental and wellbeing of refugees – a group at high risk of experiencing mental disorders who are markedly underserved in terms of services and support at both the local and global level.
Uganda 2021-08-25 2024-08-25 Social Science and Humanities Non-degree Award
James Bugeza Katamba
ID: UNCST-2021-R013970
 EPIDEMIOLOGY OF BRUCELLOSIS AT THE HUMAN LIVESTOCK INTERFACE IN UGANDA
REFNo: HS1377ES

The general objective is To characterize Brucella infections in ruminants, swine and slaughterhouse workers in Uganda. The specific objectives are 1.To determine the seroprevalence of Brucella antibodies in cattle, shoats, and pigs at selected slaughterhouses in Uganda. 2.To determine the seroprevalence of Brucella antibodies and associated risk factors among slaughterhouse workers in Uganda 3.To determine the Brucella species, biovars circulating in cattle, shoats, swine and slaughterhouse workers and their epidemiological interrelatedness 4.To determine resistance of Brucella to first line antimicrobial agents (Rifampicin and streptomycin)
Uganda 2021-08-25 2024-08-25 Medical and Health Sciences Non-Clinical Trial Degree Award
Hakim Sendagire
ID:
Clinical chemistry, hematology and other laboratory profiles of COVID 19 patients, as surrogate markers in management of severe disease
REFNo: HS1339ES

1. To describe the characteristics of peripheral blood cells in patients with varying severity of COVID-19 as compared to those who are negative
2. To describe the characteristics of the clinical chemistry and inflammatory markers in patients with varying severity of COVID-19 as compared to those who are negative
3. To establish the relationship between peripheral blood cells, clinical chemistry and cytokines and the clinical manifestation of COVID 19 and describe the potential markers for disease monitoring.

 Uganda 2021-08-25 2024-08-25 Medical and Health Sciences Non-degree Award
Stella Muyanja Zawedde
ID: UNCST-2021-R014037
 Prevalence and Outcomes of Mycobacterium bovis infection in Karamoja sub-region, North Eastern Uganda
REFNo: HS1405ES

The primary objective of this study is to determine the prevalence of M. bovis strains among patients diagnosed with TB disease in Karamoja region.,To compare six-month treatment outcomes between patients diagnosed with mycobacterium tuberculosis (M. tb) and those diagnosed with other mycobacterial species including M. bovis. ,To describe the susceptibility patterns of all mycobacterial isolates to first line medicines used in the management of drug susceptible TB. ,To describe the factors associated with having M. bovis among patients diagnosed with TB in the Karamoja region. ,
 Uganda 2021-08-25 2024-08-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Janestic Twikirize
ID:
Social Traditional Norms and child Marriage research in Zombo, Nebbi, Packwachi and Adjuman Districts, West Nile
REFNo: SS852ES

What are the roles of (Parents, Clans and relatives, Religious leaders
Cultural leaders, Boys and men in the communities and women and girls in the communities) in a) Promoting Child Marriage b) Preventing child marriage? Elaborate the roles, the specific practices and norms as well as how effective their efforts for and against CEFM are

What is the involvement of the bride-to-be in the decision-making process about her marriage?

What has been and being done to address social norms and practices that promote child early and forced marriages by boys, girls, parents, clan leaders, religious leaders, cultural leaders and community leaders?

Assess the effectiveness of what has been and being done women and girls, men and boys, parents, clan leaders, community and religious leaders to mitigate socio-cultural practices that promote child early and forced marriages

Assess the functionality and effectiveness of Community Child Protection systems from the community, district and national level. Identify strength, weakness and make recommendations to inform project intervention
 Uganda 2021-08-25 2024-08-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
Catherine Abaasa N
ID:
Quality, Safety, community perceptions and Practices on Drinking water from selected water sources in Mbarara City , South Western Uganda
REFNo: HS1469ES

i. To assess the physical chemical and microbiological quality of drinking water from selected water sources and establish the water quality index for Mbarara city.
ii. To establish the occurrence of virulence genes associated with Esherichia coli pathotypes isolated from drinking water samples from selected water sources in Mbarara city.
iii. To establish the seasonal variation in safety, quality and water quality index of water from selected water sources in Mbarara city.
iv. To explore the communities’ and water service providers’ perceptions and practices about the quality and safety of drinking water and establish possible mitigation strategies at community level.

 Uganda 2021-08-25 2024-08-25 Medical and Health Sciences Non-Clinical Trial Degree Award
Lordrick Alinaitwe
ID:
Transmission and Occurrence of Leptospira infection among humans and livestock in Uganda
REFNo: HS1563ES

To determine the extent, risk factors and potential pathways for Leptospira transmission and infection among potential reservoir animals and human populations in Uganda.,To describe potential pathways and drivers for Leptospira transmission at the animal-human-environmental interface in Uganda, based on statistical modelling,To identify Leptospira species and serogroups that circulate in humans, livestock, and environmental sources in Uganda.,To determine Leptospira seroprevalence and infection among slaughter ruminants and swine in Uganda,To determine Leptospira seroprevalence and associated risk factors among slaughter workers in Uganda,
 Uganda 2021-08-25 2024-08-25 Medical and Health Sciences Non-Clinical Trial Degree Award
Mary Goretti Nakabugo Goretti
ID: UNCST-2021-R013051
 Are our Children Learning? Uwezo Basic Assessment of Literacy and Numeracy.
REFNo: SS959ES

Uwezo Uganda intends to undertake the 2021 assessment of basic learning outcomes in literacy and numeracy in order that:
i) Independent evidence on learning levels in literacy and numeracy of children aged 4-16 in Uganda is generated.
ii) The data generated from conducting the learning assessments increases knowledge, awareness and understanding of policy actors, practitioners and the public of children’s learning outcomes and their distribution and that the evidence is used to improve resource allocation and the delivery of education.

 Uganda 2021-08-25 2024-08-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
Patrick  Vudriko
ID:
Innovations to Address Rampant Vaccine Failures, Shortages and Low Uptake for Sustainable Livestock Disease Control and Productivity in Uganda
REFNo: A136ES

The Proposal is designed to address selected immunizable diseases that affect health and productivity of poultry, small ruminant and cattle in Uganda. The study objectives include;
1. To assess the current animal vaccine supply chain and identify actors, distribution channels, use and constraints that affects animal vaccine utilization in Uganda.
2. To evaluate the level of protective Gumboro & IB virus disease antibodies among vaccinated chicken flocks in commercial farms.
3. To assess the sero-conversion of FMD vaccine and strengthen vaccination efficacy monitoring lab service at Research Center for Tropical Diseases and Vector Control (RTC) Laboratory at COVAB.
4. To assess the current PPR vaccination regimen and the clinical performance of combined PPR- SGP virus vaccine under field situations in small ruminants and develop a vaccination technical framework for effective control of the two diseases in Uganda.

Uganda 2021-08-25 2024-08-25 Agricultural Sciences Non-Clinical Trial Non-degree Award
Mike Kyewalyanga
ID: UNCST-2021-R013531
 Factors associated with virological non-suppression among HIV- Positive children under 5 years on antiretroviral therapy in Mbarara Regional Referral Hospital
REFNo: HS1584ES

1.To determine the proportion of virological non-suppression among HIV positive children under 5 years who have been on ART for at least 6 months, in the ISS clinic of Mbarara Regional Referral Hospital.

2.To determine the factors associated with virological non-suppression among HIV positive children under 5 years who are receiving ART from ISS clinic of Mbarara Regional Referral Hospital.
3.To determine the perceptions of health-care providers and parents/guardians on factors associated with virological non-suppression among HIV positive children under 5 years who are receiving ART from ISS clinic of Mbarara Regional Referral Hospital.

 Uganda 2021-08-25 2024-08-25 Medical and Health Sciences Non-Clinical Trial Degree Award
Luz Azlor del Valle
ID:
GAFSP Private Sector Window Uganda Impact Evaluation - Baseline
REFNo: SS943ES

The primary research question is – what is the impacts of an expansion in the fertiliser business on smallholder farmers. The purpose of the evaluation is to account for the interventions and support provided and to derive lessons and recommendations to improve future impact. To meet these objectives the eventual impact evaluation will attempt to answer the following evaluation questions:
1. How does the project affect yields?
2. How does the project affect household income and poverty status of farmers?
3. What is the project’s impact on food security and nutrition?
4. What is the project’s impact on women’s status and empowerment?
 Spain 2021-08-25 2024-08-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jayne Ellis
ID: UNCST-2021-R013987
 “Integrated management of cryptococcal and opportunistic infections to improve outcomes in advanced HIV disease (IMPROVE study)”
REFNo: HS1607ES

1) To generate evidence on the safety (adverse events) and feasibility (adherence and tolerability) of 1HP (one month of isoniazid and rifapentine) for TB preventative therapy (TPT) amongst adults with HIV-associated cryptococcal meningitis.
2) To generate preliminary data on potential secondary benefits (reduced loss to follow-up, reduced active TB disease, reduced mortality due to TB) of early (inpatient initiation) 1HP TPT as compared to standard (outpatient initiation) 1HP TPT amongst adults with HIV-associated cryptococcal meningitis.

UK 2021-08-25 2024-08-25 Medical and Health Sciences Clinical Trial Degree Award
Moses Joloba Lutaakome
ID: UNCST-2022-R011558
 Bacterial and Host Determinants in TB Transmission: Immune Phenotypes Associated with Exposure to High and Low Transmission Strains of MTB - Uganda
REFNo: HS1498ES

The goal of this study is to identify the bacterial and host factors that promote transmission of tuberculosis (TB), a necessary first step towards developing drugs and vaccines that prevent the inter-person spread of Mycobacterium tuberculosis (Mtb). This study has five specific aims:

Aim 1: Determine the extent to which household transmission is responsible for co-prevalent and incident TB cases caused by Mtb strains that are genetically distinct from those isolated from the index cases within the same household.

Aim 2: Investigate the in vitro immune phenotype of transmitted versus not-transmitted Mtb strains in households stratifying for HIV status.

Aim 3: Characterize the innate macrophage response to high and low transmission strains and the T-cell response in persons with known household exposure to high and low transmission isolates and the impact of HIV infection.
Aim 4: Identify the component of Mtb genes that aid in bacterial survival in aerosols.
Aim 5: Investigate the bacterial factors underlying divergence in the host response to high and low transmission isolates.


Uganda 2021-08-24 2024-08-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Peter Elyanu James
ID: UNCST-2021-R013210
 CoVPN 3008- UBUNTU Multi-Center, Randomized, Efficacy Study of COVID-19 mRNA Vaccine in Regions with SARS-CoV-2 Variants of Concern. Version 1.0, dated 16 May 2021. DAIDS Document ID # 38838.
REFNo: HS1642ES

Primary Objectives
The primary objectives of this study are to determine the following:
1. To assess vaccine efficacy (VE) of COVID-19 mRNA vaccine to prevent virologically-confirmed symptomatic COVID-19 starting 14 days after dose 2 in adults who are at risk of severe COVID-19
2. To assess vaccine efficacy (VE) of COVID-19 mRNA vaccine to prevent severe COVID-19 starting 14 days after dose 2 in adults who are at risk for severe COVID-19
3. To assess safety and tolerability of COVID-19 mRNA vaccine in adults who are at risk of severe COVID-19

Secondary Objectives
The secondary objectives of this study are to evaluate the following:
1. Durability of VE of COVID-19 mRNA vaccine against COVID-19 and against severe COVID-19 through the final study visit (Month 12 post-dose 1) in volunteers with no previous COVID-19
2. VE of COVID-19 mRNA vaccine against COVID-19 and against severe COVID-19 by neutralization phenotype and Spike sequence features of acquired SARS-CoV-2 viruses (sieve analysis), including VE against the B.1.351/501Y.V2 variant and VE against all other variants combined in volunteers with no previous COVID-19
3. VE of COVID-19 mRNA vaccine against SARS-CoV-2 infection defined by nucleocapsid protein seroconversion regardless of symptomology in volunteers with no previous COVID-19
4. VE of COVID-19 mRNA vaccine against asymptomatic SARS-CoV-2 infection defined by nucleocapsid protein seroconversion without prior occurrence of the symptomatic COVID-19 primary endpoint in volunteers with no previous COVID-19
5. Post -vaccination immune response markers as correlates of risk of COVID-19 and as correlates protection against COVID-19
6. VE of COVID-19 mRNA vaccine against COVID-19 and severe COVID-19 in all participants regardless of baseline SARS-CoV-2 status

Exploratory Objectives
The exploratory objectives of this study are to evaluate the following:
1. VE of COVID-19 mRNA vaccine against COVID-19 and severe COVID-19 by baseline HIV infection status in volunteers with no previous COVID-19 and in all volunteers regardless of previous COVID-19 status
2. VE of COVID-19 mRNA vaccine against COVID-19 and against severe COVID-19 by neutralization phenotype and Spike sequence features of acquired SARS-CoV-2 viruses (sieve analysis), including VE against the B.1.351/501Y.V2 variant and VE against all other variants combined in volunteers with no previous COVID-19 and in all volunteers regardless previous COVID-19 status
3. VE of COVID-19 mRNA vaccine against COVID-19 and severe COVID-19 in volunteers with previous COVID-19
4. Relative rate of COVID-19 and severe COVID-19 in placebo recipients with previous COVID-19 compared to vaccine recipients with no previous COVID-19
5. Assess T-cell responses in placebo recipients who develop COVID-19 compared to vaccine recipients who develop symptomatic COVID-19
6. Assess incidence of adverse birth outcomes among pregnant persons enrolled in the trial

 Uganda 2021-08-24 2024-08-24 Medical and Health Sciences Clinical Trial Non-degree Award
Perez Mujuni Perez Mbiire Batwine
ID:
Teachers' welfare, human capital and performance of Government aided primary school in Isingiro District
REFNo: SS964ES

i. To establish the relationship between teachers’ welfare and performance of government aided primary schools in Isingiro District.
ii. To establish the relationship between human capital and performance of government aided primary schools in Isingiro District.
iii. To find out the effect of combining teachers’ welfare and human capital on the performance of government aided primary schools in Isingiro District.
iv. To find out whether monitoring systems mediates teachers’ welfare and the performance of government aided primary schools in Isingiro District.
v. To find out whether monitoring systems mediates human capital and the performance of government aided primary schools in Isingiro District.

 Uganda 2021-08-23 2024-08-23 Social Science and Humanities Non-Clinical Trial Degree Award
Hasifah Namatovu Kasujja
ID:
eHealth Adoption in Uganda. What is the status? eHAU
REFNo: SS945ES

1. To inventory existing eHealth interventions in Uganda to ascertain maturity, failure and successes
2. To study the barriers and facilitators of eHealth adoption in Uganda
3. To develop a framework for successful eHealth adoption
4. To evaluate the framework for utility

 Uganda 2021-08-23 2024-08-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ronald Kiguba
ID: UNCST-2019-R000844
 Two-way risk communication mobile application use versus traditional methods of adverse drug reaction reporting in Uganda: a cluster-randomized controlled trial
REFNo: HS1366ES

This study will: i) assess the feasibility of implementing a mobile app for the reporting of ADRs associated with DTG and IPT at selected ART-sites in Uganda; ii) describe the characteristics (causality, seriousness, completeness, unexpectedness, severity, outcome) of the DTG- and IPT-linked ADR-reports submitted to NPC using the mobile app; and, iii) determine if use of the mobile app versus existing methods of ADR-reporting (paper-form and web-form) increases by 25% the number of reported ADRs linked to DTG and IPT use during 2.5 years of follow-up, iv) determine the cost and cost-effectiveness of using the mobile app versus existing methods of ADR-reporting.
 Uganda 2021-08-20 2024-08-20 Medical and Health Sciences Clinical Trial Non-degree Award
Cissy  Kityo
ID: UNCST-2021-R013663
 Multi-Center, Randomized, Efficacy Study of COVID-19 mRNA Vaccine in Regions with SARS-CoV-2 Variants of Concern.
REFNo: HS1669ES

-To assess vaccine efficacy (VE) of COVID-19 mRNA vaccine to prevent
virologically-confirmed symptomatic COVID-19 starting 14 days after dose 2 in
adults who are at risk of severe COVID-19 -2. To assess vaccine efficacy (VE) of COVID-19 mRNA vaccine to prevent severe COVID-19 starting 14 days after dose 2 in adults who are at risk for severe COVID-19 -3. To assess safety and tolerability of COVID-19 mRNA vaccine in adults who are at risk of severe COVID-19
Uganda 2021-08-20 2024-08-20 Medical and Health Sciences Clinical Trial Non-degree Award
Philippa Musoke
ID: UNCST-2021-R013523
 ViiV 205858: Open-label access to dolutegravir for HIV-1 infected children and adolescents completing IMPAACT Studies P1093 and P2019 Version 4.0 dated 10 Dec 2020
REFNo: HS1453ES

Primary
• To provide access to age appropriate formulations of dolutegravir (DTG), either as single entity DTG or as fixed dose combination (FDC) abacavir/dolutegravir/lamivudine (ABC/DTG/3TC), in an open-label protocol to eligible participant s who have completed the P1093 or P2019 parent studies.

Secondary

To assess any serious adverse events (SAEs) and any clinical or laboratory adverse events that lead to the discontinuation of IP (DTG or ABC/DTG/3TC FDC).
 Uganda 2021-08-20 2024-08-20 Medical and Health Sciences Clinical Trial Non-degree Award
Baker Lukwago
ID: UNCST-2021-R013259
 Tracking DISC project activities through integrated surveys in Uganda_Version One May 2021
REFNo: HS1481ES

This research protocol includes the DISC research that will happen from 2021 to 2024 in the DISC project’s focus geographies. The methods include several annual rounds of data collection, with 4 research methodologies: provider surveys, client exit interviews (CEIs), Household Surveys (HHS), and two follow up surveys with the individuals who participate in the CEIs.

Research Objectives
1. To understand exposure to information about self-injectable contraceptives in the DISC sentinel areas.
2. To understand knowledge and attitudes about self-injectable contraceptives among women in DISC sentinel areas.
3. To understand sexual and reproductive health empowerment among women of reproductive age and SI users in DISC sentinel areas.
4. To understand users’ experiences with self-injection training
5. To understand providers’ knowledge and attitudes regarding self-injectable contraceptive service provision.
6. To understand initiation and continuation of self-injection following training.
7. To gain lessons regarding client exit survey methodology for future survey implementation among self-inject clients.
8. To gain learnings regarding follow-up methodologies for future survey implementation among self-inject clients, particularly as relates to continuation measurement.

 Uganda 2021-08-20 2024-08-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Deo Wabwire Ogema
ID: UNCST-2021-R013932
 COVPN 3008: Multi-Center, Randomized, Efficacy Study of COVID-19 mRNA Vaccine in Regions with SARS-CoV-2 Variants of Concern. Version 1.0 16 May 2021
REFNo: HS1659ES

The primary objectives are:
•To assess vaccine efficacy (VE) of COVID-19 mRNA vaccine to prevent virologically-confirmed symptomatic COVID-19 starting 14 days after dose 2 in adults who are at risk of severe COVID-19
•To assess vaccine efficacy (VE) of COVID-19 mRNA vaccine to prevent severe COVID-19 starting 14 days after dose 2 in adults who are at risk for severe COVID-19
•To assess safety and tolerability of COVID-19 mRNA vaccine in adults who are at risk of severe COVID-19

Secondary objectives are to evaluate the following:
•Durability of VE of COVID-19 mRNA vaccine against COVID-19 and against severe COVID-19 through the final study visit (Month 12 post-dose 1) in volunteers with no previous COVID-19
•VE of COVID-19 mRNA vaccine against COVID-19 and against severe COVID-19 by neutralization phenotype and Spike sequence features of acquired SARS-CoV-2 viruses (sieve analysis), including VE against the B.1.351/501Y.V2 variant and VE against all other variants combined in volunteers with no previous COVID-19
•VE of COVID-19 mRNA vaccine against SARS-CoV-2 infection defined by nucleocapsid protein seroconversion regardless of symptomology in volunteers with no previous COVID-19
•VE of COVID-19 mRNA vaccine against asymptomatic SARS-CoV-2 infection defined by nucleocapsid protein seroconversion without prior occurrence of the symptomatic COVID-19 primary endpoint in volunteers with no previous COVID-19
•Post -vaccination immune response markers as correlates of risk of COVID-19 and as correlates protection against COVID-19
•VE of COVID-19 mRNA vaccine against COVID-19 and severe COVID-19 in all participants regardless of baseline SARS-CoV-2 status
gestational age)
The exploratory objectives are to evaluate:
•VE of COVID-19 mRNA vaccine against COVID-19 and severe COVID-19 by baseline HIV infection status in volunteers with no previous COVID-19 and in all volunteers regardless of previous COVID-19 status
•VE of COVID-19 mRNA vaccine against COVID-19 and against severe COVID-19 by neutralization phenotype and Spike sequence features of acquired SARS-CoV-2 viruses (sieve analysis), including VE against the B.1.351/501Y.V2 variant and VE against all other variants combined in volunteers with no previous COVID-19 and in all volunteers regardless previous COVID-19 status
•VE of COVID-19 mRNA vaccine against COVID-19 and severe COVID-19 in volunteers with previous COVID-19
•Relative rate of COVID-19 and severe COVID-19 in placebo recipients with previous COVID-19 compared to vaccine recipients with no previous COVID-19
•Assess T-cell responses in placebo recipients who develop COVID-19 compared to vaccine recipients who develop symptomatic COVID-19
•Assess incidence of adverse birth outcomes among pregnant persons enrolled in the trial

 Uganda 2021-08-20 2024-08-20 Medical and Health Sciences Clinical Trial Non-degree Award
Edwin Nuwagira
ID: UNCST-2021-R013488
 Improving Pulmonary function after Tuberculosis (IMPACT) at Mbarara Regional Referral Hospital. The incidence, clinical characteristics and factors associated with post-tuberculosis obstructive pulmonary disease at Mbarara Regional Referral Hospital (MRRH)
REFNo: HS1579ES

To determine the incidence, clinical characteristics and factors associated with post-tuberculosis obstructive pulmonary disease at Mbarara Regional Referral Hospital ,
 Uganda 2021-08-20 2024-08-20 Medical and Health Sciences Non-Clinical Trial Degree Award
Umaru Ssekabira Byansansa
ID:
Assessing COVID-19 sero-prevalence from routine antenatal care visits in Moyo and Adjumani Districts, Uganda, 2021-2022
REFNo: HS1628ES

The aim of this activity is to determine COVID-19 sero-prevalence from women attending antenatal clinics for their first ANC visit in Moyo and Adjumani Districts from April 2021 to September 2022.
The specific objectives of this sero-prevalence assessment shall be to:
•Measure the sero-prevalence of antibodies to COVID-19 in the population of pregnant women attending first ANC by age group, in order to ascertain the cumulative population immunity
•Monitor trends and detect emerging hotspots of COVID-19 in selected geographic areas

 Uganda 2021-08-20 2024-08-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Doreen Chemutai
ID:
Pathways, Perceptions and Performance: A comparative Analysis of Women on Open and Reserved Seats in Uganda’s 10th Parliament
REFNo: SS971ES

i. To comparatively analyze the motives of women MPs on the reserved and open seats for seeking parliamentary seats in Uganda’s 10th parliament.
ii. To document the experiences of women members of parliament on the reserved and open seats of their journey to parliamentary seats.
iii. To explain voter’s perceptions of performance of women members of parliament on reserved and open seats.
iv. To evaluate the performance differences of women MPs on the reserved and opens seats of representation and legislation

 Uganda 2021-08-20 2024-08-20 Social Science and Humanities Non-Clinical Trial Degree Award
Annet Nanvubya
ID: UNCST-2025-R015525
 Randomized, Efficacy Study of COVID-19 mRNA Vaccine in Regions with SARS-CoV-2 Variants of Concern version 1.0 16-05-2021.
REFNo: HS1677ES

Primary Objectives
The primary objectives of this study are to determine the following:
• To assess vaccine efficacy (VE) of COVID-19 mRNA vaccine to prevent virologically-confirmed symptomatic COVID-19 starting 14 days after dose 2 in adults who are at risk of severe COVID-19
• To assess vaccine efficacy (VE) of COVID-19 mRNA vaccine to prevent severe COVID-19 starting 14 days after dose 2 in adults who are at risk for severe COVID-19
• To assess safety and tolerability of COVID-19 mRNA vaccine in adults who are at risk of severe COVID-19

Secondary Objectives

The secondary objectives of this study are to evaluate the following:
• Durability of VE of COVID-19 mRNA vaccine against COVID-19 and against severe COVID-19 through the final study visit (Month 12 post-dose 1) in volunteers with no previous COVID-19
• VE of COVID-19 mRNA vaccine against COVID-19 and against severe COVID-19 by neutralization phenotype and Spike sequence features of acquired SARS-CoV-2 viruses (sieve analysis), including VE against the B.1.351/501Y.V2 variant and VE against all other variants combined in volunteers with no previous COVID-19
• VE of COVID-19 mRNA vaccine against SARS-CoV-2 infection defined by nucleocapsid protein seroconversion regardless of symptomology in volunteers with no previous COVID-19
• VE of COVID-19 mRNA vaccine against asymptomatic SARS-CoV-2 infection defined by nucleocapsid protein seroconversion without prior occurrence of the symptomatic COVID-19 primary endpoint in volunteers with no previous COVID-19
• Post -vaccination immune response markers as correlates of risk of COVID-19 and as correlates protection against COVID-19
• VE of COVID-19 mRNA vaccine against COVID-19 and severe COVID-19 in all participants regardless of baseline SARS-CoV-2 status
gestational age)

Exploratory Objectives
The exploratory objectives of this study are to:
• VE of COVID-19 mRNA vaccine against COVID-19 and severe COVID-19 by baseline HIV infection status in volunteers with no previous COVID-19 and in all volunteers regardless of previous COVID-19 status
• VE of COVID-19 mRNA vaccine against COVID-19 and against severe COVID-19 by neutralization phenotype and Spike sequence features of acquired SARS-CoV-2 viruses (sieve analysis), including VE against the B.1.351/501Y.V2 variant and VE against all other variants combined in volunteers with no previous COVID-19 and in all volunteers regardless previous COVID-19 status
• VE of COVID-19 mRNA vaccine against COVID-19 and severe COVID-19 in volunteers with previous COVID-19
• Relative rate of COVID-19 and severe COVID-19 in placebo recipients with previous COVID-19 compared to vaccine recipients with no previous COVID-19
• Assess T-cell responses in placebo recipients who develop COVID-19 compared to vaccine recipients who develop symptomatic COVID-19
• Assess incidence of adverse birth outcomes among pregnant persons enrolled in the trial


 Uganda 2021-08-20 2024-08-20 Medical and Health Sciences Clinical Trial Non-degree Award
Judith Kobusinge
ID:
Effect of selected soil moisture conservation practices on water budgeting in Robusta coffee in Uganda
REFNo: A117ES

1) To predict the effect of soil moisture on Robusta coffee production and productivity in Uganda. 2) To estimate the water use efficiency (WUE) of Robusta coffee at various phenological stages under Albizia coriaria and Open sun 3) To determine the effect of selected soil moisture conservation practices on soil-water relations in Robusta coffee agro-systems.
Uganda 2021-08-19 2024-08-19 Agricultural Sciences Non-Clinical Trial Degree Award
Patrick OJOK
ID:
Teachers’ Perceived Preparedness to Implement the Competency-Based Lower Secondary Curriculum
REFNo: SS810ES

Purpose of the Study The primary purpose of this study is to determine the perceptions of preparedness of lower secondary teachers and explore the factors hindering and/or facilitating the implementation of the new LS curriculum in Uganda. Research Objectives 1) Determine the perceived preparedness of lower secondary school teachers to implement the new lower secondary curriculum. 2) Explore the school and teacher-factors that facilitate/hinder the implementation of the new lower secondary curriculum. 3) Identify the support that lower secondary teachers need to improve their capacity to implement the new LS curriculum.
Uganda 2021-08-19 2024-08-19 Social Science and Humanities Non-Clinical Trial Non-degree Award
Christopher Dolan Gerald
ID:
"changing gender norms and gender-responsive humanitarian action in Uganda”
REFNo: SS858ES

 To examine gendered norms, roles and power relations changed during and after forced displacement;
 To explore how existing knowledge on gender issues informed design of the current refugee response; and
 To find out implications for humanitarian agencies of observed changes in gender roles, norms and power relations

 UK 2021-08-17 2024-08-17 Social Science and Humanities Non-Clinical Trial Non-degree Award
Elizabeth Najjingo
ID:
Factors that influence false tooth extraction among children below two years in Isingiro, Southwestern Uganda.
REFNo: SS952ES

To explore alternatives that can be used instead of false tooth extraction,To explore outcomes of the practice false tooth extraction,To identify methods used for false tooth extraction in Isingiro district.,To explore factors responsible for false tooth extraction within Isingiro district.,To explore factors responsible for the practice of false tooth extraction and methods used in Isingiro district in South Western Uganda.,
 Uganda 2021-08-17 2024-08-17 Social Science and Humanities Non-Clinical Trial Non-degree Award
Munshi Sulaiman
ID:
Mobile money, privacy, security and women’s empowerment: Exploring the impact pathways of digital finance for women’s empowerment
REFNo: SS907ES

This research aims to assess the mechanisms (e.g. security and privacy) through which digital transfers may increase women’s agency and economic empowerment. The study will answer a number of research questions including:
• Are digital transfers more adequate instruments compared to cash transfers for improving women’s economic empowerment?
• Do digital transfers increase women’s privacy over financial information?
• Does privacy of information enhance the women’s enactment of choices?
• Does the secure nature of mobile money transfers significantly impact WEE outcomes?
• Which DFS pathways play a greater role in enhancing women’s agency and enactment of choices; security of money or privacy of information?
Bangladesh 2021-08-17 2024-08-17 Social Science and Humanities Non-Clinical Trial Non-degree Award
Laura Sirabella
ID:
Translating sustainable development goals to address poor reproductive health: exploring the role of civil society organisations
REFNo: SS949ES

The objectives of this study are to:
- explore the role of CSOs in translating the SDGs in the context of reproductive health in effective policies;
- explore how CSOs implement such policies;
- investigate how CSOs advocate for the implementation of policies aimed at addressing reproductive health;
- elaborate the role of CSOs in promoting individual and community’s agency to advocate for reproductive justice.
 Italy 2021-08-17 2024-08-17 Social Science and Humanities Non-Clinical Trial Degree Award
Akulia Agnes
ID:
UNDERSTANDING ACCESS TO SCHOOL LEADERSHIP: A CASE OF WOMEN IN PUBLIC PRIMARY SCHOOLS IN KOBOKO DISTRICT, UGANDA
REFNo: SS623ES

The main objective of this study is to establish how women in school leadership been able to navigate their way into leadership positions. Specifically the study will establish factors that motivate women to pursue school leadership positions, the barriers women have to navigate to access positions of school leadership and the strategies women use to enhance them access school leadership positions.
 Uganda 2021-08-16 2024-08-16 Social Science and Humanities Degree Award
Joseph  Olobo Okao Olobo
ID:
A multicentre observational study to assess immune response status in patients before and after treatment for visceral leishmaniasis
REFNo: HS1266ES

Primary Objective To assess systemic and skin immune responses and parasite load in patients before, and at end of treatment for visceral leishmaniasis
Secondary Objectives
1. To identify systemic and local immune correlates of treatment outcome.
2. To evaluate parasite genotype in relation to immune response characteristics
3. To compare immunology and parasitological data across each site and determine possible correlates of progression to PKDL


 Uganda 2021-08-16 2024-08-16 Medical and Health Sciences Non-degree Award
Joseph  Matovu KB
ID: UNCST-2020-R014654
 Formative research to inform the design of a youth-led self-care intervention to increase uptake of voluntary family planning and reproductive health care services among adolescent girls (10-19 years) in Uganda
REFNo: HS1294ES

The overall objective of the study will be to explore adolescent girls perceptions towards provision of self-care FP services and stakeholders’ perceptions towards provision of voluntary FP and RHC information and services to adolescent girls aged 10-19 years by fellow adolescents in order to inform the design of a youth-led self-care intervention to improve uptake of voluntary FP and RHC services to adolescent girls aged 10-19 years in Uganda. Specifically, this study will aim to:
1. Determine differentials in teenage pregnancy rates and contraceptive use by socio-demographic and behavioural characteristics
2. Assess the association between modern contraceptive use and teenage pregnancy rates among adolescents (15-19 years) across the different demographic and health surveys.
3. Explore the FP and RHC information and service needs of the very young adolescent girls (10-14 years) and older adolescents (15-19 years).
4. Explore mechanisms through which adolescent girls (10-19 years) can be involved in the design and delivery of voluntary FP and RHC interventions for fellow adolescents.
5. Explore adolescent girls’ perceptions about self-care FP methods and whether or not self-care FP methods can help to reduce the barriers that adolescents face in accessing and utilizing FP services.
6. Explore key stakeholders’ perceptions towards: a) provision of self-care FP information and services to adolescents; and b) provision of voluntary FP and RHC information and services to adolescent girls aged 10-19 years by fellow adolescents.
7. Explore key stakeholders’ perceptions on the acceptability of an intervention that entails provision of FP and RHC information and services to adolescent girls (10-19 years) by fellow adolescent girls.
8. Explore the barriers to and facilitators of interventions that provide FP and RHC information and services to adolescent girls by adolescent girls in the target districts and how provision of such information and services to adolescent girls by fellow adolescent girls can be improved.
 Uganda 2021-08-16 2024-08-16 Medical and Health Sciences Non-degree Award
Elizeus Rutebemberwa
ID: UNCST-2022-R009070
 Advancing the health of rural communities in Uganda through strong community health programs
REFNo: SS872ES

4.3 General Objective
To evaluate non-monetary incentive packages required for strengthening the community health workforce, which provides critical health services to the rural poor in Masindi District.

Specific objectives
i. To identify the priorities of the national government regarding compensation packages for the VHTs in Masindi District.
ii. To assess how the national government compensation packages align with the priorities of the VHTs in Masindi District.
iii. To identify the structure and group of incentives best suited to motivate VHTs, improve their performance in the delivery of services, and increase their retention in the health workforce in Masindi District.
iv. To identify the behavioural mechanism through which the new incentives may work or fail to work in Masindi District
v. To understand how changes in the national VHT program impact utilization of maternal and child health services, sanitary practices and perception of quality of health services at the community-level



 Uganda 2021-08-16 2024-08-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
Manjari Quintanar-Solares
ID:
MICROARRAY PATCH FOR PEDIATRIC ANTIRRETROVIRAL TREATMENT STAKEHOLDER INTERVIEWS IN UGANDA
REFNo: HS1359ES

To define the target product profile (TPP) and preferred user characteristics, identify stakeholder needs, and evaluate potential acceptability of a pediatric ARV MAP
 Mexico 2021-08-16 2024-08-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eun Seok Kim
ID:
Cross-sectional prevalence study of schistosomiasis and soil-transmitted helminthiasis with nested open-label randomised controlled study of evaluating the impact of fatty meal co-administration and double-dosing on albendazole effectiveness against hookworm infection among school-aged children in Mayuge district: Implications for Mayuge NTDs Elimination (MANE) Project
REFNo: HS1411ES

Objective 1: To determine the effect of albendazole administration with a fatty meal such as avocado, versus albendazole administration without a fatty meal, on hookworm cure rate and egg reduction rate.

Objective 2: To determine the effectiveness of dual-dose (400mg/day, two consecutive days) versus single-dose (400mg) albendazole treatment regimens on hookworm cure rate and egg reduction rate.

Objective 3: To identify and evaluate environmental, social and cultural variables affecting hookworm infection, and cure rate and egg reduction rate of albendazole against hookworm.

 South Korea 2021-08-16 2024-08-16 Medical and Health Sciences Clinical Trial Degree Award
Carmen  Logie
ID: UNCST-2021-R013185
 Kuwawezesha Vijana (Empowering Youth): An HIV Self-Testing and Comic Intervention with Refugee Adolescents and Youth in a Refugee Settlement in Northern Uganda
REFNo: SS884ES

The primary study aim is to compare the effectiveness of adding HIV self-testing, education- comics, or both to the standard of care approaches of HIV testing among refugee youth in Bidi Bidi in increasing HIV status knowledge.
The primary outcome is HIV testing uptake (HIV status knowledge, verified through asking HIV serostatus and verifying with voluntary point of care testing).
The secondary outcomes include HIV knowledge, HIV-related stigma, use of SRH services (e.g., condoms, contraception), and linkage to a clinic for confirmatory testing.
 Canada 2021-08-16 2024-08-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
Doris Kakuru
ID:
Representation of Young Motherhood: Performing young womanhood, subjectivities and agency in Sexual and Reproductive Health in Uganda
REFNo: SS960ES

To find out the implications of representations of young motherhood on reproductive justice,To establish alternatives of young parenthood which are made available through motherhood performances by young mothers in Uganda (Including their lived experiences, identity formation and agency to adhere, comply or resist dominant subjectivities). ,To examine how dominant notions about young motherhood affect SRHR rights of young mothers in Uganda.,To ascertain how dominant assumptions of young motherhood by different SRHR actors position young mothers in urban poor locales in Uganda. ,
 Uganda 2021-08-16 2024-08-16 Social Science and Humanities Non-Clinical Trial Degree Award
Rosalind  Parkes-Ratanshi Parkes
ID: UNCST-2019-R000717
 Acceptability and feasibility of mhealth technology for sensitization and contact follow up for high-risk communities for infectious disease outbreaks; Call for Life-COVID (CFL-C) and Call for Life Ebola (CFL-E)
REFNo: SS865ES

1.To document experiences of using an IVR service to support COVID positive patients and for those in COVID quarantine.
2.To evaluate the acceptability of using an IVR service for post COVID-19 mental health screening in Uganda.
3.To assess feasibility of using an IVR service for outbreak response, through documentation of the experience and lessons learned of using CFL-C by health care workers, policy makers, developers and implementing actors
4.To explore barriers and enablers to health seeking behaviour and vaccinations, perceptions/ stigma/ fears/concerns of COVID and other epidemic outbreaks including EVD and mitigation measures (e.g. cancelling funerals – Ebola, school and business closures – COVID, including comparisons of the two) within at risk and hard to reach communities.

UK 2021-08-16 2024-08-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
Stella Muyanja Zawedde
ID: UNCST-2021-R014037
 Computer aided detection of Tuberculosis using chest radiography: A clinical validation of the CAD4TB version 7 system.
REFNo: HS1575ES

The primary objective will be to:
a) To determine the sensitivity and specificity of different CAD4TB v7 scores for the detection of bacteriologically confirmed tuberculosis (using Xpert Ultra® as the reference standard) in the Ugandan population.

The secondary objectives will be to
b) To determine the optimal combination of symptoms and chest x-ray features to be used to when triaging patients at the outpatient and HIV clinics.
To determine the most cost-effective algorithm to be used while to screen for TB among patients presenting to the outpatient and HIV clinics in Gulu and Kitgum.

Uganda 2021-08-16 2024-08-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
VICTOR TUMUKUNDE SPECTOR
ID:
Assessment of the validity of the measurement of kangaroo mother care duration in a hospital in Uganda: an observational study
REFNo: HS1589ES

o To assess the accuracy of caregiver report on duration of skin-to-skin contact (SSC) in the KMC position among neonates ≤2000g before stabilization.
o To assess the accuracy of healthcare workers’ report on duration of SSC in the KMC position among neonates ≤2000g before stabilization.
o To assess the reproducibility of the two methods of measuring KMC duration.
o To assess the reliability (inter-observer agreement) of gold standard direct observation.

 Uganda 2021-08-16 2024-08-16 Medical and Health Sciences Non-Clinical Trial Degree Award
Stephen Watya
ID: UNCST-2025-R021507
 UNDERSTANDING PROSTATE CANCER IN MEN OF AFRICAN ANCESTRY.
REFNo: HS1514ES

GENERAL OBJECTIVE
The goal of this project is to understand the genetics and epidemiology of prostate cancer in men of African ancestry.
Specific Objectives (SO):
1. To study common and rare germline variation in association with prostate cancer risk in men of African ancestry, using cutting edge genotyping and sequencing techniques. (UGPCS)
2. To determine non-genetic risk factors associated with prostate cancer among men of African ancestry. (UGPCS)
3. To identify germline and tumor genomic/molecular determinants of aggressive prostate cancer and disease progression in men of African ancestry. (UGPCS)
4. To determine the acceptability and validity of a rapid screening kits for prostate cancer in the Ugandan population. (UGPCS-epi)
5. To assess population level determinants of high PSA (≥4 n/gm) in men of African ancestry (UGPCS-epi).
6. To explore whether circulating tumor cells and circulating tumor DNA can be detected in the blood of men with aggressive prostate cancer and may be used to screen for aggressive disease (UGPCS-screen).
7. To determine disease progression of prostate cancer from the time of presentation among Ugandan men. (UGPCS-screen).

 Uganda 2021-08-16 2024-08-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Violet Korutaro
ID: UNCST-2019-R000618
 IMPAACT 2017: Phase I/II Study of the Safety, Acceptability, Tolerability, and Pharmacokinetics of Oral and Long-Acting Injectable Cabotegravir and Long-Acting Injectable Rilpivirine in Virologically Suppressed HIV-Infected Children and Adolescents. Short title: ‘MOCHA’ (More Options for Children and Adolescents), DAIDS # 30070, IND # 138,754
REFNo: HS1512ES

To assess the safety of CAB LA + RPV LA through Week 24 in HIV-infected, virologically suppressed adolescents,To confirm the doses for oral CAB followed by injectable CAB LA in HIV-infected, virologically suppressed adolescents by evaluating: Safety and multiple dose PK of oral CAB through Week 4, Safety and multiple dose PK of CAB LA through Week 16, and to confirm doses for injectable RPV LA in HIV-infected, virologically suppressed adolescents by evaluating safety and multiple dose PK of RPV LA through Week 16,To confirm the dose and evaluate the safety, tolerability, acceptability, and pharmacokinetics (PK) of oral cabotegravir (CAB), long-acting injectable cabotegravir (CAB LA), and long-acting injectable rilpivirine (RPV LA) in virologically suppressed HIV‐1 infected children and adolescents aged 12 to <18 years.,
 Uganda 2021-08-16 2024-08-16 Medical and Health Sciences Clinical Trial Non-degree Award
Helen Ndagije Byomire
ID: UNCST-2021-R013939
 Skepticism on the Safety and Quality of Generic Medicines from countries with Non-stringent Regulatory Authorities in Uganda.
REFNo: HS1550ES

3. To establish knowledge, attitude and perceptions of health workers and the general population towards generic medicines from countries with the SRAs and those from the N-SRA including Uganda.,2. To compare the quality of selected registered generic medicines on the Ugandan market sourced from countries with SRAs and those from N-SRA including Uganda against the innovator product. ,1. To compare the nature and proportion of adverse drug reactions (ADRs) received by NDA in the period of June 2016 to June 2020 for selected generics from SRAs and those from the N-SRA against the innovator product.,To compare the quality and safety of selected generic medicines on the Ugandan market sourced from countries with Stringent Regulatory Authorities (SRAs) with those from non-stringent regulatory authorities N-SRAs including Uganda. ,
 Uganda 2021-08-16 2024-08-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jonathan Kayondo
ID: UNCST-2021-R008325
 Multi-Centre, Prospective, Evaluation for Matrix equivalence of capillary whole blood finger-stick and fresh and frozen venous whole blood with the NxTekâ„¢ Malaria Pf Plus Rapid Test Device and NxTekâ„¢ Malaria Pf/Pv Plus Rapid Test Device for the Detection of Plasmodium Infections in Patients with Symptoms Suggestive of Malaria within the Lab and its intended use environment for CE IVDR.
REFNo: HS1587ES

This trial is part of the R&D Verification and Validation studies, to provide clinical matrix equivalence evaluation to support the conformity assessment procedure for the use of fingerstick and venous whole blood samples with Abbott’s NxTek™ Malaria Pf Plus and NxTek™ Malaria Pf/Pv Plus Rapid Test Devices, as performed by professional users, in accordance with WHO PQ TSS-3, WHO PQ Dossier, EU 2017/7461.

Primary Objective: Matrix Equivalence
To assess the matrix equivalence of:
a. Fresh CWBFS and Fresh VWB
b. Frozen VWB and Fresh VWB
when used with the NxTekâ„¢ Malaria Pf/Pv Plus and NxTekâ„¢ Malaria Pf Plus by laboratory professionals (from hereon referred to as Lab operators) in a laboratory environment to support CE IVDR certification.

The test results of the NxTekâ„¢ Malaria Pf Plus and NxTekâ„¢ Malaria Pf/Pv Plus Rapid Test using a VWB sample, will be evaluated against the NxTekâ„¢ Malaria Pf Plus and NxTekâ„¢ Malaria Pf/Pv Plus Rapid Test using CWBFS sample from the same participant. In summary: Fresh CWBFS vs. Fresh VWB*. Likewise, the test results of the NxTekâ„¢ Malaria Pf Plus and NxTekâ„¢ Malaria Pf/Pv Plus Rapid Test using VWB samples that have been exposed to 1x Freeze/Thaw cycle will be evaluated against the NxTekâ„¢ Malaria Pf Plus and NxTekâ„¢ Malaria Pf/Pv Plus Rapid Test using fresh VWB samples from the same participant. In summary: Frozen VWB vs. Fresh VWB*

*indicates: Where Fresh VWB will be the comparator sample type.

The data obtained will be used in the application for CE IVDR certification and WHO PQ. Paired CWBFS and VWB samples will be taken from the same individuals for testing on both NxTekâ„¢ Malaria Pf/Pv Plus and NxTekâ„¢ Malaria Pf Plus RDTs.

Secondary Objective: Intended Users within the Intended Use Environment
Malaria RDTs are used outside of the laboratory for near patient testing (NPT)* by non laboratory healthcare workers with limited training. Thus the secondary objective of this study is to assess the perfromance of the NxTekâ„¢ Malaria Pf/Pv Plus and NxTekâ„¢ Malaria Pf Plus results when used in its intended environment (NPT setting) by intended users (non laboratory healthcare workers with limited training) using CWBFS as the sample type.*see NPT definition Section 4.2-4.3 of protocol (or below sections on trial operator types and trial envitronment types).

 Uganda 2021-08-16 2024-08-16 Medical and Health Sciences Clinical Trial Non-degree Award
Rhoda Wanyenze
ID: UNCST-2021-R013352
 PILOT OF A NETWORK-DRIVEN, ADVOCACY INTERVENTION TO PROMOTE CERVICAL CANCER SCREENING IN UGANDA (PHASE 3)
REFNo: HS1633ES

The proposed intervention development study seeks to improve cervical cancer screening in Uganda by engaging and training local public health researchers and program implementers, and empowering women living with cervical cancer risk (WLCCR), defined as women who have ever received CC screening procedures, to advocate for CC screening and early treatment among women in their social networks.
 Uganda 2021-08-16 2024-08-16 Medical and Health Sciences Clinical Trial Non-degree Award
Vandana Sharma
ID:
Assessing StrongMinds’ Community-based Therapy Groups with a Gender Lens
REFNo: SS954ES

The overall objective of this research is to better understand gender outcomes of StrongMinds programming, including the experience of women participants of both in-person and remote IPT-G with respect to safety and GBV risks.
 Canada 2021-08-16 2024-08-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
Achilles Katamba
ID: UNCST-2019-R000540
 Validating a Clinical Risk Score for early Management of Tuberculosis in Ugandan Primary Health Clinics - PredicTB study
REFNo: HS1622ES

1. To evaluate the effectiveness of the PredicTB clinical risk score on clinical outcomes. 2. To evaluate the implementation of the PredicTB clinical risk score. 3. To project the long-term impact and cost-effectiveness of PredicTB implementation.
Uganda 2021-08-16 2024-08-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Denis Muhangi
ID:
Enhancing Institutional Capacity for Ethical Conduct of Research Involving Animals
REFNo: A141ES

Program objectives
1. To enhance technical capacity of MakSVAR-IACUC to international accreditation level.
2. Establish an Institutional Biosafety committee at the College of Veterinary Medicine, Animal Resources and Biosecurity.
3. To enhance awareness of the national guidelines for the use of animals in research and teaching among researchers and training institutions.

Specific study objectives

1. To determine the status of practices for the ethical conduct for research involving animals in Uganda.
2. To evaluate the available practices for ethical conduct for intervention.

Uganda 2021-08-16 2024-08-16 Agricultural Sciences Non-Clinical Trial Non-degree Award
Kenneth Ssebambulidde Ssebambulidde
ID: UNCST-2021-R013976
 Relationship between maternal or newborn cholesterol levels and neonatal septicaemia: A Ugandan cohort of mother-new-born pairs
REFNo: HS1204ES

Primary objective: To elucidate a relationship between maternal and neonatal cholesterol levels and neonatal septicaemia

Secondary objectives:
1. To determine whether abnormal maternal cholesterol levels are associated with a risk for neonatal septicaemia.
2. To describe the correlation between maternal cholesterol levels and cord blood neonatal cholesterol levels at birth.
3. To determine the association between cord blood cholesterol levels and neonatal septicaemia

Uganda 2021-08-11 2024-08-11 Medical and Health Sciences Non-degree Award
ANTHONY KAYIIRA
ID: UNCST-2020-R014108
 Prognostic value of serum hCG-β level, 12 days after embryo transfer, on predicting live birth among Ugandan women.
REFNo: HS1569ES

4. To determine the sensitivity and specificity of serum hCG-β level cut offs, 12 days after embryo transfer, on predicting pregnancy loss,3. To determine the sensitivity and specificity of serum hCG-β level cut offs, 12 days after embryo transfer, on predicting clinical pregnancy ,2. To determine the sensitivity and specificity of serum hCG-β level cut offs, 12 days after embryo transfer, on predicting biochemical pregnancy ,1. To determine the sensitivity and specificity of serum hCG-β level cut offs, 12 days after embryo transfer, on predicting live birth,To evaluate the prognostic value of serum hCG-β level cut off, 12 days after embryo transfer, on predicting pregnancy outcome among Ugandan women following an IVF-ET cycle.,
 Uganda 2021-08-11 2024-08-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Abel Atukwase
ID:
EXPOSURE ASSESSMENT AND ANALYSIS OF HEALTH RISKS ASSOCIATED WITH CONSUMPTION OF AFLATOXIN CONTAMINATED STAPLES IN UGANDA
REFNo: A132ES

The overall objective of the project is to generate information that will guide the development of evidence-based policies and strategies for management of health risks associated with aflatoxins in Uganda. The specific objectives are to;
1. Determine the levels of aflatoxins in maize, sorghum and groundnuts produced and consumed in Uganda
2. Assess aflatoxin exposure among children (6-59 months) and women of reproductive age (15-49 years)
3. Characterise the health risks associated with consumption of maize, sorghum and groundnuts among children 6-59 months and women of reproductive age (15-49 years)
4. Develop policy briefs aimed at improving awareness amongst policy makers and stimulate formulation of policies and strategies for mitigating aflatoxin associated health risks.
 Uganda 2021-08-11 2024-08-11 Agricultural Sciences Non-Clinical Trial Non-degree Award
Maxensia owor
ID: UNCST-2021-R014003
 IMPAACT 2017: Phase I/II Study of the Safety, Acceptability, Tolerability, and Pharmacokinetics of Oral and Long-Acting Injectable Cabotegravir and Long-Acting Injectable Rilpivirine in Virologically Suppressed HIV-Infected Children and Adolescents. Version 3.0, dated 13 August 2020
REFNo: HS1356ES

Primary Objectives:
Cohort 1
1.To confirm the doses for oral CAB followed by injectable CAB LA in HIV-infected, virologically suppressed adolescents
2.To confirm doses for injectable RPV LA in HIV-infected, virologically suppressed adolescents by evaluating safety and multiple dose PK of RPV LA through Week 16
Cohort 2:
1.To assess the safety of CAB LA + RPV LA through Week 24 in HIV-infected, virologically suppressed adolescents
Secondary Objectives: Cohort 1
• To monitor maintenance of viral suppression through Week 16 in HIV-infected, virologically suppressed adolescents
• To evaluate the tolerability and acceptability of CAB LA through Week 16 in HIV-infected,virologically suppressed adolescents
• To evaluate the tolerability and acceptability of RPV LA through Week 16 in HIV-infected,virologically suppressed adolescents
Secondary Objectives: Cohort 2
• To assess safety of oral CAB + oral RPV followed by CAB LA + RPV LA through Week 48 in HIVinfected, virologically suppressed adolescents
• To evaluate repeat-dose pharmacokinetics of CAB LA + RPV LA through Week 24, and through
Week 48 in HIV-infected, virologically suppressed adolescents.
• To assess antiviral activity of CAB LA + RPV
 Uganda 2021-08-11 2024-08-11 Medical and Health Sciences Clinical Trial Non-degree Award
John Gitta Kavuma
ID:
Corporate Governance and Christian Organisational Culture in Anglican Church Founded Universities in Uganda
REFNo: SS794ES

1-To analyse the effect of corporate governance on university policies in Ndejje and UCU.

2-To assess the relationship between governing Policies and Christian values at Ndejje and UCU

3-To evaluate the influence of Christian values on organizational culture of Ndejje and UCU.

4-To compute the contribution of Corporate Governance on promoting Christian
organizational culture.
 Uganda 2021-08-11 2024-08-11 Social Science and Humanities Non-Clinical Trial Degree Award
Jimmy, Maguru Mugisha Maguru
ID:
The ‘unexpected visitors’ and ‘good-host’ discourse: Social Accountability, Policy and Realities of Sexual and Reproductive Health of young people in two refugee settlements in Uganda
REFNo: SS828ES

1. To examine governance and accountability mechanisms of sexual and reproductive
health service delivery of the young refugees in refugee settlements in Uganda.
2. To examine the role of young refugees in the governance mechanisms of SRH and the
accountability chain and how this influences their ability to voice and to access SRH
services in refugee settings
3. To explore the challenges faced by young refugees and their coping mechanisms in
accessing and utilizing the ASRH services in refugee settlements in Uganda.

 Uganda 2021-08-11 2024-08-11 Social Science and Humanities Non-Clinical Trial Degree Award
Violet Nakibuuka
ID: UNCST-2021-R003675
 PREVALENCE AND FACTORS ASSOCIATED WITH HUMAN PAPILLOMA VIRUS VACCINATION AMONG ADOLESCENTS GIRLS AGED 9 TO 19 YEARS LIVING WITH HIV AT MULAGO ISS CLINIC, KAMPALA, UGANDA
REFNo: HS1436ES

1. To determine the prevalence of HPV vaccination among HIV positive adolescent girls aged 9-19 years at Mulago ISS Clinic, Kampala, Uganda.
2. To determine the factors associated with HPV vaccination among HIV positive adolescent girls aged 9-19 years at Mulago ISS Clinic Kampala, Uganda
3. To explore the perspectives, perceptions and experiences of healthcare providers, adolescent girls and their care takers at Mulago ISS Clinic regardingHPV vaccination among HIV positive adolescent girls.

Uganda 2021-08-11 2024-08-11 Medical and Health Sciences Non-Clinical Trial Degree Award
Derry Taylor James
ID:
Learned social knowledge in chimpanzees
REFNo: NS269ES

To understand the nature of chimpanzee social knowledge and how it is acquired
 UK 2021-08-11 2024-08-11 Natural Sciences Non-Clinical Trial Non-degree Award
MOSES EGESA
ID: UNCST-2025-R015361
 Epitope mapping of schistosome tegument and alimentary tract proteins in humans
REFNo: HS1463ES

1. To determine the change in antibody reactivity profile of individuals of an endemic area to epitopes of tegument and alimentary tract proteins before and after PZQ treatment
2. To identify antibody reactivity to epitopes putatively associated with protection against reinfection


 Uganda 2021-08-11 2024-08-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Pontiano  Kaleebu
ID: UNCST-2020-R019901
 Field Performance Evaluation of the m-PIMAâ„¢ HIV-1/2 VL plasma assay in Uganda
REFNo: HS1606ES

Main objective
To evaluate the field performance of the m-PIMATM HIV-1/2 VL plasma VL in identifying virological failure (VF) in adults on ART. The performance will be compared to standard PCR assays used at UNHLs and UVRI.
2.3.2 Primary objectives
I). To evaluate the diagnostic accuracy using the sensitivity, specificity, NPV, PPV, FPR and FNR of the m-PIMAâ„¢ HIV-1/2 VL plasma assay in comparison to a reference assay of HIV-1 RNA PCR in identifying HIV-VF at the WHO recommended threshold of 1000 copies/ml for HIV-1 infected.
II). To determine the operational characteristics of the m-PIMAâ„¢ HIV-1/2 VL plasma assay, such as ease of-use of the assay using the standardized system usability scale (SUS) by laboratory and no laboratory personnel
III). To determine changes in turn-around time and ease of clinic workflow integration.
IV).To determine acceptability of the m-PIMAâ„¢ HIV-1/2 VL plasma assay by the study participants

 Uganda 2021-08-11 2024-08-11 Medical and Health Sciences Clinical Trial Non-degree Award
Hiroyuki Takeshima
ID:
Introducing market-oriented horticulture farming in refugee hosting areas of Uganda: An intervention that builds resilience against emergency
REFNo: SS946ES

The objective of the proposed study is to introduce training programs to farmer groups in Northern Uganda, that aim to improve the market profitability of horticulture and thus increase incomes and employment for small farmers in these refugee-hosting regions in Uganda. Such investments are urgently needed to stabilize livelihoods in this region that has suffered through the combinations of challenges posed by the influx of refugees and other challenges including desert locust invasions, and health and economic risks caused by the COVID-19 pandemic. Specifically, the training program target fostering of lead farmers who will then further train other farmers within the community, and transform farmers’ mindset to “produce strategically to sell” rather than “produce and then sell”. Disseminating knowledge through lead farmers (also sometimes known as “model farmers” “village agents”) to a wider group of farmers has been considered an important way to reach and enhance the capacity and mindset of farmers at scale. The program will contribute to stabilizing and boosting farm incomes in vulnerable, refugee-hosting communities and will build the resilience of local livelihoods to COVID-19. The study then collects data on farmers’ market interaction activities and farm production practices before and after the training programs to assess the impacts of these training programs.
 Japan 2021-08-11 2024-08-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
HAPPY WALUSAGA.G. ANNET
ID:
Patients’ Perceptions and Factors Influencing Choice of differentiated service delivery (DSD) models of care in Kampala, Uganda: A Case Study of Immune Suppression Syndrome (ISS)-Clinic Mulago
REFNo: SS957ES

1.To determine the prevalence of utilization of Community clients Led ART model of care among HIV/AIDS clients at ISS clinic- Mulago
2.To determine the factors associated with patients choice of CCLAD model of care among HIV/AIDS clients at ISS clinic- Mulago
3.To explore patients’ perceptions regarding the HIV differentiated models of care

 Uganda 2021-08-11 2024-08-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
Charity Okaba
ID:
Addressing barriers to HIV self-testing in the Private sector among young sexually active females and males in Uganda: A human centred design framework to developing private sector HIVST demand creation, distribution, and linkage models
REFNo: SS955ES

PSI and the Busara Center for Behavioral Economics will conduct qualitative market research that will use targeted questions to gather opinions on barriers and enablers of HIV self-testing in the private sector to uncover insights, opportunities, motivators, and unmet needs. Specifically, the research will employ in-depth interviews and focus group discussions to gather insights on both demand and supply aspects of HIVST as these relate to sexually active females and males of ages 18- 29.

Focus group discussions and in-depth interviews shall be conducted among potential beneficiaries, sexually active females and males of 18 – 29 years to better understand the perceptions and attitudes, barriers and motivators of these groups towards HIV self-testing and responding to the questions with regards to the design of interventions, including delving into the issues or experiences that exacerbate behavioral biases, thereby affecting uptake of HIVST by these populations. The focus group discussions shall consider individuals with experience of using HIV self-test kits and those without experience.
We will also conduct in-depth interviews with private pharmacists, pharmaceutical technologists, and retailers of community drug shops for an understanding of the service provider perspective in selling HIV self-test kits to the target population. In addition, we will also conduct in-depth interviews with manufacturers and distributors of HIV self-test kits to understand supply side barriers and interventions that may hinder or facilitate uptake of HIVST by the target population. Further, we will conduct in-depth interviews with Ministry of Health officials in charge of managing the national HIVST programs including regulatory mechanisms to understand policy and regulatory side barriers and interventions for rolling out HIVST in the private sector.
Uganda 2021-08-10 2024-08-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
 A parallel-group, Phase III, multi-stage, modified double-blind, multi-armed study to assess the efficacy, safety, and immunogenicity of two SARS-CoV-2 Adjuvanted Recombinant Protein Vaccines (monovalent and bivalent) for prevention against COVID-19 in adults 18 years of age and older
REFNo: HS1638ES

1. To assess, in participants who are SARS-CoV-2 naïve, the
clinical efficacy of the CoV2 preS dTM-AS03 vaccines for
the prevention of symptomatic COVID-19 occurring ≥ 14
days after the second injection.

2. To assess the safety of the CoV2 preS dTM-AS03 vaccines
compared to placebo throughout the study.
 Uganda 2021-08-10 2024-08-10 Medical and Health Sciences Clinical Trial Non-degree Award
Twalib Aliku Olega
ID: UNCST-2019-R000474
 Uganda Heart Institute Cardiac Catheterization Registry: Patient profile, procedural complications and long-term outcomes
REFNo: HS1081ES

1) to determine the clinical and demographic profile of patients undergoing cardiac catheterization at the UHI
2) to describe complications associated with adult and pediatric cardiac catheterization procedures performed at the UHI and
3) to describe the immediate and intermediate outcomes of patients undergoing adult and pediatric interventional cardiac catheterization at the UHI

 Uganda 2021-08-09 2024-08-09 Medical and Health Sciences Non-degree Award
Stephen Sabiiti
ID:
CLINICAL AND HEMATOLOGICAL OUTCOMES OF CHILDREN WITH SICKLE CELL ANEMIA TREATED WITH LOW FIXED-DOSE HYDROXYUREA AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS1314ES

1. To describe the clinical and hematological
features of children with sickle cell
anemia at initiation of low fixed-dose
hydroxyurea at MRRH.
2. To describe the changes in hematological
indices after initiation of low fixed dose
hydroxyurea among children with sickle
cell disease at MRRH.
3. To describe the incidence of sickle cell
anemia related clinical events among
children with sickle cell disease treated
with low fixed-dose hydroxyurea at MRRH.
4. To identify factors associated with the
changes in hemoglobin level among children
with sickle cell anemia treated with
low fixed-dose hydroxyurea at MRRH.
 Rwanda 2021-08-06 2024-08-06 Medical and Health Sciences Non-Clinical Trial Degree Award
Elizabeth Kemigisha Kemigisha
ID:
Adolescents’ Perspectives of sexual wellbeing and consent MUST-2021-37
REFNo: HS1438ES

1) To contribute to the understanding about how local and contextual factors such as predominant religion, socially acceptable norms, cultural practices and political sentiment can influence sexual wellbeing of adolescents (10 to 24 year olds) in LMIC’s, 2) To explore adolescents’ understanding of, and perspectives on, sexual wellbeing, capturing different aspects of sexuality development during adolescence, including the evolving capacity to sexual consent,
 Uganda 2021-08-06 2024-08-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ADOA DENNIS
ID:
Development and Evaluation of a Psychosocial Risk Assessment Tool for Predicting Attrition From HIV Care And Treatment Amongst Adolescents Aged 15-19 Years in Uganda
REFNo: HS1501ES

To assess the feasibility of HCWs administering the psychosocial risk assessment tool to ALHIV aged 15-19 years during routine ART visits to determine risk for attrition ,To evaluate the ability of the tool to predict risk of attrition of ALHIV aged 15-19 years at 3-months, following their enrollment date,Assessment and validation of the risk assessment tool, To develop a psychosocial risk assessment tool,To develop a psychosocial assessment tool for predicting attrition of adolescents aged 15-19 years from HIV care. ,
 Uganda 2021-08-06 2024-08-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Achilles Katamba
ID: UNCST-2019-R000540
 EVALUATION OF TRUENAT MTB-RIF DX AND TRUENAT MTB ASSAYS IN COMPARISON TO GENEXPERT MTB/RIF ULTRA FOR THE DIAGNOSIS OF PULMONARY TUBERCULOSIS
REFNo: HS1526ES

Primary:
• Assess sensitivity and specificity of Truenat™ MTB-RIF Dx and Truenat™ MTB assays in raw sputum compared to the WHO-endorsed GeneXpert® MTB/RIF Ultra using culture as the gold standard

Secondary:
• Assess the operational feasibility of Truenat™ MTB-RIF Dx and Truenat™ MTB assays
• Determine and compare costs between the Truenat™ MTB-RIF Dx and Truenat™ MTB assays, and Xpert MTB/RIF Ultra
 Uganda 2021-08-06 2024-08-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Allan Lugaajju
ID:
Community-Based Cardiovascular Disease risk factors assessment in Wakiso and Mpigi districts
REFNo: HS1556ES

1. To determine the prevalence of cardiovascular disease risk factors (hypertension, dyslipidemia, obesity, diabetes, physical inactivity, diet, and age) in Wakiso and Mpigi districts
2. To determine the status of cardiac function of the study participants in Wakiso and Mpigi districts.
3. To explore determinants of life-style factors (physical activity, tobacco and alcohol use) through interviews and focus group discussions
 Uganda 2021-08-06 2024-08-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Robert Kent Kirya Robert
ID:
Validity and Reliability of Force Inventory in Ugandan Secondary Schools
REFNo: NS275ES

Based on the constructed rationale, this study aims to present the quality of the FCI to the Ugandan context in terms of its validity, reliability, level of difficulty, powers of discrimination, and distractors of items.,The main purpose of the study is to establish the validity and reliability of Force Inventory in Ugandan Secondary Schools. ,
 Uganda 2021-08-05 2024-08-05 Natural Sciences Non-Clinical Trial Degree Award
Jolly Magulu
ID: UNCST-2021-R013833
 Psychiatric comorbidities of Epilepsy and treatment gaps among children and adolescents attending children\'s outpatient of Butabika National Referral Mental Hospital in Kampala, Uganda
REFNo: HS1465ES

General objective
To determine the prevalence of psychiatric comorbidities of epilepsy and determine the diagnostic deficit and treatment gaps among children and adolescents attending children’s Outpatient at Butabika National Referral mental hospital in Kampala, Uganda.

Specific objectives
1.) To determine the prevalence of psychiatric co-morbidities of epilepsy among children and adolescents attending children’s Outpatient at Butabika National Referral mental hospital.
2.) To determine the proportion of children and adolescents with untreated psychiatric comorbidities of epilepsy attending children’s Outpatient of Butabika National Referral mental hospital.
3.) To establish the patient factors associated with untreated psychiatric comorbidities among children and adolescents with epilepsy attending children’s Outpatient of Butabika National Referral mental hospital.
4.) To find out clinician reflections untreated psychiatric comorbidities among children and adolescents with epilepsy attending children’s Outpatient of Butabika National Referral mental hospital.
 Uganda 2021-08-05 2024-08-05 Medical and Health Sciences Non-Clinical Trial Degree Award
Robert Kent Kirya Robert
ID:
Developing a Circular Motion Concept Inventory for evaluating understanding of students of Ugandan Secondary Schools.
REFNo: NS274ES

iii) To evaluate the students’ conceptual change using the circular motion concept inventory's pre-test and post-test scores. ii) Use the circular motion concept inventory to examine the level of conceptual understanding of secondary school students. i) To adapt and validate the statistical indices of circular motion concept inventory.
 Uganda 2021-08-05 2024-08-05 Natural Sciences Non-Clinical Trial Degree Award
Susan Kironde Kizito
ID:
THE ROLE, KNOWLEDGE, ATTITUDE AND PRACTICES OF TRADITIONAL HEALERS IN THE MANAGEMENT OF SNAKE BITES: A CASE OF GULU AND KAMULI DISTRICTS, UGANDA
REFNo: HS1434ES

1.Describe the role of traditional healers in the management of snakebites. 2.Assess the knowledge traditional healers have on snakes, snake bite symptoms and signs, and management of snakebite envenoming. 3.Describe the attitude traditional healers have about snakes, and the modes of first aid they use for management of snakebites. 4.Document traditional healers’ practices when providing first aid to snakebite victims. 5.Establish the willingness of traditional healers to contribute towards establishing a community surveillance system for snakebites in Uganda.
Uganda 2021-08-04 2024-08-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Pontiano Kaleebu
ID: UNCST-2021-R013577
 An open label, Phase 2 study to evaluate the safety and immunogenicity of an Ad26.ZEBOV booster dose in Human Immunodeficiency Virus Positive (HIV+) adults previously vaccinated with the Ad26.ZEBOV, MVA-BN-Filo vaccine regimen
REFNo: HS1350ES

• To assess the safety and tolerability of a Ad26.ZEBOV booster dose in HIV positive adults previously vaccinated with the Ad26.ZEBOV, MVA-BN-Filo vaccine regimen.

• To assess humoral responses induced by the booster dose against EBOV glycoprotein (GP), as measured by Filovirus Animal Non-Clinical Group (FANG) Enzyme-Linked Immunosorbent Assay (ELISA) at 7 and 21 days.

 Uganda 2021-08-04 2024-08-04 Medical and Health Sciences Clinical Trial Non-degree Award
Sarah Zalwango Karen
ID: UNCST-2021-R005660
 Identifying adolescents at high risk of neurocognitive disorder: Development and validation of composite risk index.
REFNo: HS1532ES

a. To develop a CRI by combining intake data on nutrition, immune parameters and HIV status and their interactions and perform internal and external validation of CRI as predictor of ND at 12 months. We hypothesize that the CRI evaluated at intake will successfully predict progressive/incident ND 12 months later.

b. To further internally and externally validate CRI for “out-of-time-window” prediction from 24 to 36 months. We hypothesize that the CRI developed at intake but evaluated at 24 months will successfully predict progressive/incident ND at 36 months.

c. For HEU and HIV-infected children, to refine CRI into CRI-HEU and CRI-HIV, respectively, by including type of maternal ART, viral genome parameters, current cART regimen/adherence (as applicable), and their interactions. We hypothesize that the CRI-HEU and CRI-HIV developed at intake and evaluated at intake and 24 months will successfully predict ND and ND/HAND respectively, 12 months later.

 Uganda 2021-08-04 2024-08-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mary Goretti Nakabugo Goretti
ID: UNCST-2021-R013051
 DEVELOPING SUSTAINABLE MODELS FOR COMMUNITY-BASED PRESCHOOLS IN UGANDA
REFNo: SS714ES

The purpose of this study is to identify and refine models of ECCE provision which can help to increase its availability and enhance its quality in the context of Uganda. It is intended that these models should involve community ownership and management as far as possible and should be suitable for public subsidy in the future.

The main research questions are as follows and will apply to a variety of cases selected for in-depth and comparative study:

1. What structures, practices and resources can enable the preschool to be controlled by, and accountable to, representatives of a local community or other relevant community?

2. What structures, resources and system of funding can help to make the preschool accessible and affordable to all or most households in the locality? How far can these elements be sourced within the community?

3. What are the essential human and physical resources for the preschool to be of acceptable quality and how should the standards for these be stated for purposes of management and evaluation? How far can the community provide these resources?

4. Given the existing provision of resources, what should be the priorities for improving leadership, teaching and care in the preschool?

5. How can the preschool best be linked with schools, health and social welfare services and existing demand-side interventions?

 Uganda 2021-08-03 2024-08-03 Social Science and Humanities Non-degree Award
ANN NANTEZA SENGENDO
ID:
Assessment of integrated control of East Coast fever (ECF) by induction of acquired immunity in Ankole cattle after natural infection by early diagnosis and early treatment
REFNo: A134ES

Mainobjective
To investigate the performance of early diagnosis and early treatment of ECF as a method of reducing calf mortality and enhancing conditions for the development of endemic stability
Specific objectives
i. To determine the prevalence of ECF based on microscopic, ELISA and PCR methods.
ii. To determine the efficiency of early symptom diagnosis and early chemotherapy approach in treating natural ECF cases and induction of protective immunity against ECF in Ankole cattle in an endemic area.
iii. To design a diagnostic regimen/protocol that farmers can use to minimize cattle losses due to ECF by integrating early case symptom detection and early treatment in the routine control strategy in an endemic area.


 Uganda 2021-08-03 2024-08-03 Agricultural Sciences Non-Clinical Trial Non-degree Award
Kenneth Rubango
ID:
Feasibility Study of Nanomedicine in Uganda
REFNo: HS1485ES

Design a nanomedicine promotion package that will be shared with Makerere University, the Ministry of Health and the other healthcare providers. ,Study and evaluate the effectiveness of nanomedicine towards the existing medical education in the selected medical schools. Under this aim, the teaching staff e.g Assistant lecturers, Lecturers, Associate Professors or Professors will be interviewed for the necessary information.,Engage employers and employees in designing the feasibility study towards nanomedicine at their workplaces. Under this aim, the employers e.g Administrators, Principals or Human resource managers will be interviewed for the necessary information.,Assess employer’s willingness to support interventions geared at promoting nanomedicine at their workplaces. Under this aim, the employers e.g Administrators, Principals or Human resource managers will be interviewed for the necessary information.,Conduct formative research to assess existing and needed support for nanomedicine in the selected medical schools. Under this aim, the Key Informant person from each medical school will be interviewed. ,To design and evaluate the feasibility study of nanomedicine in the selected Ugandan medical schools.,
 Uganda 2021-08-03 2024-08-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Cally Tann
ID: UNCST-2023-R008021
 Transitioning a Bundle for Early Detection and Intervention for Children with Developmental Disability to Scale for Low-Resource Settings
REFNo: SS910ES

WS1: To develop harmonised training materials to promote and support high fidelity implementation of the PDC and ABAaNA EIP at scale.
WS2: To further develop the Ubuntu multi-media web platform including development of a pilot mobile tablet application to promote programme accessibility and fidelity.
WS3: To identify existing approaches to livelihood support for caregivers of children with developmental disability in low- and middle-income countries to inform the development of a livelihoods component to the EIP.
WS4: To develop a scale-up strategy, business model and marketing strategy to disseminate the PDC and EIP approaches to a wider audience.
WS5: To define a sustainable monitoring, evaluation and learning strategy to track implementation of the PDC and EIP at scale

 UK 2021-08-03 2024-08-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
Frederick Kijjambu Nsambu
ID:
PERFORMANCE OF MICROFINANCE DEPOSIT TAKING INSTITUTIONS; A MACROECONOMIC AND INSTITUTIONAL PERSPECTIVE IN UGANDA
REFNo: SS932ES

5To establish the relationship between ownership structure and performance of MDI in Uganda. ,i4 To establish the competition on the performance of MDIs in Uganda.,3To establish the impact of outreach on performance of MDIs in Uganda.,To establish the impact of external factors on the performance of MDIs in Uganda.,To establish the impact of internal factors on the performance of MDIs in Uganda.,To establish performance of microfinance deposit taking institutions in Uganda,
 Uganda 2021-08-03 2024-08-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
Moses Joloba Lutaakome
ID: UNCST-2022-R011558
 Validation of the new BP- TB LAM LFA test in well-defined urine and plasma samples collected from TB patients irrespective of HIV status
REFNo: HS1527ES

Primary:
• To collect urine and plasma samples for validation studies on the selection of the best prototype among the six TB LAM LFA prototypes generated by Biopromic (BP)

Secondary:
• To create a biobank of plasma and urine for future validation of novel TB diagnostics

 Uganda 2021-08-03 2024-08-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
TUKAMUHABWA EVARISTO
ID:
Curriculum innovation, school environment and physics teacher effectiveness. The case of the SESEMAT program in Kabale Municipality, Uganda
REFNo: SS837ES

1. To establish the relationship between curriculum innovation and teacher effectiveness.
2. To find out the relationship between school environment and teacher effectiveness.
3. To establish whether school environment has a moderating effect on the relationship between curriculum innovation and teacher effectiveness.

Uganda 2021-08-02 2024-08-02 Social Science and Humanities Non-Clinical Trial Degree Award
Eddy Walakira Joshua
ID: UNCST-2022-R009077
 Uganda Overseas Labor Recruitment—Forced Labor Prevalence Study
REFNo: SS940ES

Specific objectives
In specific terms, the study will generate data that establishes the:

a) Prevalence of forced labour and labour exploitation among overseas (middle east) labour returnees to Uganda

b) Characteristics of overseas labor, including hours worked, renumeration, freedom of movement, and recruitment among others

c) Determining the profiles of the different segments in the subpopulations among labour migrants
 Uganda 2021-08-02 2024-08-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Daniella CHUSYD Elyse
ID:
Anthropogenic related stress on reproduction in African forest elephants (Loxodonta africana cyclostis)
REFNo: NS137ES

(i) To determine how human activity influences elephant stress and reproduction.

(ii) To assess Elephants’ allostatic load (measure of the wear and tear on the body) in relation to proximity to humans.

(iii) To determine Elephants’ reproductive cycling status (is the elephant cycling or not) in relation to the elephant’s allostatic load.

USA 2021-07-30 2024-07-30 Natural Sciences Non-degree Award
Joeri Smits Smits
ID: UNCST-2021-R013841
 Reducing comparison frictions in the Ugandan credit market
REFNo: SS733ES

• To evaluate the source of comparison frictions for borrowers in the Ugandan credit market: cognitive cost of calculating the total cost of credit versus a lack of information on cost (components).
• To elicit valuations (Willingness-To-Pay (WTP))
• To evaluate the effectiveness of three types of interventions in terms of the extent to which they can help (potential) borrowers’ access cheaper and/or larger loans:
- Price aggregator tool, requiring the user to collect the pricing data him/herself
- Information provision, in the form of a table showing the potential borrower the interest rate, its calculation method, and the various fees and charges associated with a comparable loan from different institutions.
- A price aggregator that at once provides the Total Cost of Credit for a comparable loan across institutions.
 Netherlands 2021-07-30 2024-07-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
David Obot Obot
ID:
Uptake of Public Health Practices for Prevention of COVID-19 among Refugees, Pastoralist Communities, Truck Drivers and Slum Dwellers in Uganda
REFNo: SS838ES

1) Establish how culture, information, attitudes and practices unique to targeted communities influence the risk of COVID-19 transmission.
2) Promote culturally sensitive radio and mobile phone communication to enhance awareness of the COVID-19 prevention; specifically, the relevance and the importance of community engagement and local solutions.


3) Examine the role of trust in health organization with the aim to build local community capacity to respond to pandemics, and to gather local evidence that can inform health policy and humanitarian response.

 Uganda 2021-07-30 2024-07-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
Andrew Semulimi Weil Matabi
ID: UNCST-2021-R013568
 SERUM BIOMARKERS OF VASCULAR ENDOTHELIAL CELL ACTIVATION AMONG PEOPLE LIVING WITH HIV ON LONG-TERM ANTI-RETROVIRAL THERAPY IN UGANDA.
REFNo: HS1468ES

• To describe the serum levels of biomarkers associated with vascular endothelial cell activation among PLWHA on long term ART.
• To determine the factors associated with vascular endothelial cell activation among PLWHA on long term ART.

 Uganda 2021-07-30 2024-07-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Adrian Muwonge
ID:
Tracking Haulage in East Africa to support COVID-19 surveillance- THEA-C19
REFNo: HS1565ES

The objectives of this study is to develop and test a digital track and trace system(DTTS) tailored to haulage in Uganda which is at the centre of the East African haulage network. By consultatively doing this, we ensure it meets the recommended standards of DTTS but also examine its impact on sector, public benefit, as well as the legal, ethical and individual rights boundaries.
 Uganda 2021-07-30 2024-07-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan Babirye
ID: UNCST-2021-R013201
 Expert Clients’ delivered Cognitive Behavioral Therapy for Reducing Self-Stigma among HIV positive Pregnant Young Women and Adolescent Girls Living in Slums Areas of Kampala, Uganda
REFNo: HS1488ES

This research broadly aims to provide evidence about expert client-delivered CBT model for reducing HIV Self-stigma in a resource limited setting.To achieve this, four interrelated questions are proposed;
1) How effective is the expert client-delivered CBT model in reducing or influencing self-stigma?
2) Can trained expert clients effectively provide CBT sessions?
3) Can expert client-delivered CBT model be accepted by clients and implementers?
4) What are the factors that contribute to acceptance of CBT delivered by expert clients?
5) What are the contextual factors that favor or hinder implementation of the expert client-delivered CBT model?

 Uganda 2021-07-30 2024-07-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Noeline Nakasujja
ID: UNCST-2019-R001428
 A collaborative research program between Michigan State University and Makerere University psychiatry departments on climate change and gender-based violence in Uganda
REFNo: HS1517ES

To conduct key-informant interviews with key personnel in the identified organizations and other stakeholders.,To identify institutions and stakeholders in based in Kampala but who work in other Ugandan regions as well related to climate change mitigation and adaptation and GBV prevention.,To establish the initial activities and steps for the development of a joint MSU-MU research program in mental health factors associated with GBV and climate change. ,
 Uganda 2021-07-30 2024-07-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Godfrey  Siu
ID: UNCST-2021-R005439
 Implementation Science and Impact evaluation of the parenting for respectability programmes: A hybrid CRCT Design”
REFNo: SS900ES

The overall objective of this study is to conduct a cRCT evaluation of PfR to test its effectiveness and cost-effectiveness for reducing violence against children and gender based violence.

1. Test the effectiveness of PfR in modifying key outcomes on parent-child relationships and relationships between partners that underlie violence against children and girls/women.
2. Examine the cost effectiveness of PfR using incremental cost-effectiveness analyses (CEA) based both on the primary outcomes of harsh parenting and partner conflict as well as on disability-adjusted life years (DALYs).
3. Examine how three implementation variables – rural vs peri-urban locality, previously established groups vs new groups, and professional vs non-professional facilitators – affect participation, programme fidelity, and quality of delivery (measured quantitatively);
4. Examine the impact of implementation variables – participant engagement and quality of delivery by facilitators – on primary outcomes of parent- and child-report of harsh parenting and partner conflict.
5. Qualitatively investigate the five elements of implementation: (i) what training facilitators need (length, follow-up, who delivers training, location, etc.); (ii) what supervision facilitators need (frequency, by whom, nature of feedback, etc.); (iii) targeting of PfR at the most vulnerable families and how this can be done; (iv) disseminating PfR’s messages beyond those participating in group sessions to operate at a community, as well as individual, level; (v) differences between Wakiso and Amuru Districts in facilitative and hindering contextual factors. We will explore how these affect participation, programme fidelity, quality of delivery, participant response and community-wide impact.

 Uganda 2021-07-30 2024-07-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
Erisa Mwaka Sabakaki
ID: UNCST-2019-R001625
 DESIGN AND FABRICATION OF A LUMBAR MODIFIED SPINAL BRACE
REFNo: HS1558ES

Our main objective is to design, fabricate and test a modified fit-for-purpose lumbar orthosis through use of locally available raw materials whose design can be adopted by different orthopaedic workshops in low income countries. This will be achieved through the following sub aims;
1. Conduct a needs assessment to determine the needs and requirements of people with low back pain and derive specifications for a modified brace well suited for use by people in LICs.
2. Test and assess the functionality of the modified brace using simulations.
3. Fabricate a sturdy brace with locally sourced components that suits the specifications derived from the simulations so as to make it suitable for use in low income countries.

 Uganda 2021-07-30 2024-07-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Allen Kabagenyi
ID:
Accelerating Covid-19 Vaccine Acceptance and Uptake in Uganda: Snapshot Study
REFNo: SS951ES

(3) To assess the community perceptions and barriers towards COVID-19 vaccine uptake.,The general objective of the study is to explore the factors and facilitators for COVID-19 vaccination acceptance and uptake. ,To explore the demographic and socio-economic factors associated with accelerated uptake and acceptance to receive a COVID-19 vaccination. ,(1) Examine the preparedness of the population and essential workers to receive the COVID-19 vaccine. ,
 Uganda 2021-07-30 2024-07-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
Abubakar Mustafa Sadik
ID: UNCST-2021-R013642
 Willingness to use genetically modified crops: Case study of communities in Uganda
REFNo: SS738ES

General objective: To evaluate the willingness of communities in Uganda to use genetically modified (GM) crops in order to inform policies and develop targeted interventions and programs towards the introduction and scaling up of GM crops in the Ugandan market. Specific objectives: a) To assess level of knowledge of communities of GM crops in Bushenyi, Jinja and Wakiso districts b) To evaluate perceptions of communities towards GM crops in Bushenyi, Jinja and Wakiso districts c) To assess the factors that contribute towards the knowledge and perceptions of communities towards GM crops in Bushenyi, Jinja and Wakiso districts d)To link willingness to use GM crops with the knowledge and perceptions of communities in Bushenyi, Jinja and Wakiso districts
 Uganda 2021-07-29 2024-07-29 Social Science and Humanities Non-Clinical Trial Non-degree Award
Hanifah Nabbanja
ID:
Characterizing oncology-related emergencies among cancer patients attending the emergency unit of Uganda Cancer Institute, Kampala, Uganda in 2019
REFNo: HS1282ES

(1) To describe the demographics and tumor characteristics, laboratory markers, and the presenting signs and symptoms in cancer patients attending the emergency unit of the Uganda Cancer Institute (UCI), Uganda from 01 January 2019 to 31 December 2019.

(2) To determine the factors associated with the different clinical presentations of oncology-related emergencies among cancer patients attending the emergency unit of the Uganda Cancer Institute (UCI), Uganda from 01 January 2019 to 31 December 2019.
 Uganda 2021-07-29 2024-07-29 Medical and Health Sciences Non-degree Award
Peter Rukundo Milton
ID: UNCST-2020-R014799
 Nutritional Quality and Safety of Complementary Foods for Children in Landslide-prone Bududa District
REFNo: HS982ES

(i) Describe the diversity of meals and food combinations commonly used in the complementary feeding of children 6-23 months old in Bududa district. (ii) Analyse the nutrient and chemical composition of commonly used raw and cooked complementary foods. (iii) Identify the type and levels of micro-organisms in the food and water commonly used for complementary feeding.
Uganda 2021-07-28 2024-07-28 Medical and Health Sciences Non-degree Award
Suzanne  Kiwanuka N
ID: UNCST-2020-R014671
 COVID-19: Assessment of the COVID-19 Response in Eastern, Central and Western Africa
REFNo: HS1121ES

The aim of this research is to assess and curate the (i) response to the COVID-19 pandemic in Africa and the outcomes in terms of COVID-19 control and (ii) continuity of essential non-COVID-19 services within the COVID-19 period, to inform the COVID-19 response and recovery as well as health system resilience to future disease outbreaks in Africa.
 Uganda 2021-07-28 2024-07-28 Medical and Health Sciences Non-degree Award
Diane Nabikolo
ID:
DEVELOPMENT OF A SAFE READY TO EAT BHAJIA SNACK FORTIFIED WITH GRASSHOPPER (Ruspolia differens) FLOUR IN UGANDA
REFNo: A121ES

i. To establish food safety knowledge, attitudes and indigenous practices associated with safe harvesting and processing of R. differens at the household level.
ii. To determine potential allergens associated with R. differens and prevalence of allergic reactions from their consumption and handling
iii. To evaluate the effect of processing on quality and safety of bhajia snack enriched with R. differens flour
iv. To determine consumer preferences and willingness to pay for value-added ready to eat bhajia snack fortified with R. differens flour.

 Uganda 2021-07-28 2024-07-28 Agricultural Sciences Non-Clinical Trial Degree Award
Irene Andia Biraro Rebecca
ID: UNCST-2019-R001475
 Pregnancy Associated Tuberculosis: Immunological and Clinical Outcomes of Exposed Infants.
REFNo: HS1396ES

4. To determine TB treatment outcomes of mothers with pregnancy associated tuberculosis.,3. To determine the prevalence of maternal comorbidities such as hyperglycaemia, malaria, HIV, syphilis and anaemia.,2. To explore the concept of congenital TB (defined as TB acquired during the intrauterine period or during the normal birth process) among infants born to women with active TB.,Secondary objectives 1. To estimate the prevalence of active TB among pregnant and postpartum mothers seeking care from antenatal clinics and TB treatment units.,3. To describe the clinical outcomes of the women with pregnancy associated TB (defined as a diagnosis of TB during pregnancy or within six months of the postpartum period) and their exposed infants at the different time points. ,2. To explore, in a subset of infants, T cell, B cell and NK cell responses following stimulation with TB antigens.,Primary objectives 1. To compare antibody vaccine responses to BCG, measles, tetanus among children born of mothers diagnosed with TB infection or disease during pregnancy or mothers on TB treatment within a six months’ postpartum period.,To compare antibody vaccine responses in children born of mothers diagnosed with diagnosed with TB infection or disease during pregnancy or mothers on TB treatment within a six months’ postpartum period.,
 Uganda 2021-07-28 2024-07-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jonathan Izudi
ID: UNCST-2019-R000469
 Evaluating the acceptability of the Aqua Research STREAM Disinfection Generator in healthcare facilities in Uganda
REFNo: HS1467ES

The proposed acceptability study will evaluate levels of user and key stakeholder acceptability of the STREAM at the end of the initial introduction stage. Results will inform national STREAM introduction strategies
 Uganda 2021-07-28 2024-07-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joseph Baluku B
ID: UNCST-2019-R000612
 Prevalence of Soil transmitted HElminths and correlation with Cardiovascular risk factors among patients with drug resistant TuBerculosis in Uganda: a cross sectional multi-center study (SHEC-TB study)
REFNo: HS1521ES

2. To establish the correlation between soil transmitted helminths co-infection and BMI, HbA1C, blood pressure, serum lipids and the CVR score among patients with DR-TB in Uganda,1. To determine the burden of soil transmitted helminths co-infection among patients with DR-TB in Uganda,
 Uganda 2021-07-28 2024-07-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
William Worodria Ofuti
ID: UNCST-2022-R010915
 Rapid Research in Diagnostics Development for TB Network (R2D2 TB Network) Study
REFNo: HS1482ES

1. To evaluate early and late prototypes of novel TB diagnostics to provide feedback to developers on performance and usability, inform further development and identify potential strategies for use in endemic settings.
2. To conduct large-scale, multi-center assessments of the accuracy and usability of design-locked novel TB diagnostics, including in special populations, to facilitate World Health Organization (WHO) policy review.
3. To assess the potential costs and epidemiological impact of novel TB diagnostics alone or in combination with current tests and algorithms to inform their further assessment and/or the WHO policy review process.
 Uganda 2021-07-28 2024-07-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rhona Baingana Kezabu
ID: UNCST-2021-R013638
 THE 2021 DHS-8 PILOT
REFNo: HS1529ES

To compare hemoglobin concentrations between venous blood, a single drop of capillary blood, and a pooled capillary blood sample in children age 6-59 months and non-pregnant women age 15-49 in a laboratory setting and a field setting,To program and pilot collection of other types of data (for assessing/ensuring interview data quality),To improve various aspects of the CAPI data capture process,To test the computer-assisted personal interviewing (CAPI) data collection application for new sections of the questionnaire ,To understand the performance of selected new core questions and modules with respect to aspects that can be assessed through cognitive interviewing: comprehension, retrieval, judgement, and response,To test selected core questions, new modules, the Domestic Violence module, and a number of the CAPI innovations under field conditions for the eighth round of The Demographic and Health Surveys (DHS) Program. ,
 Uganda 2021-07-28 2024-07-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Gertrude Namale
ID:
Post-discharge Care for Stroke patients in Uganda: barriers and enablers of appropriate secondary preventive care, coping mechanisms and access to rehabilitation service
REFNo: HS1522ES

Overall aim
To improve the quality of life of stroke survivors in Uganda by examining the barriers and enablers of appropriate care and support following discharge from hospital.

Specific objectives
1. To examine the barriers and enablers of stroke survivors’ participation in self-reported home-based physical activity and adherence to clinic follow-up schedules post-discharge

2. To document the experiences and opinions of facility-based health care providers on post-discharge follow-up and care for stroke patients

3. To describe the coping mechanisms among stroke survivors and their caregivers after discharge (a) adjustment to lifestyle behaviour post-stroke b) needs and concerns; c) depression symptoms

4. To document barriers and facilitators related with access to rehabilitation services among stroke patients post-discharge

Uganda 2021-07-28 2024-07-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Edgar Agaba
ID:
A framework for improving the effectiveness of integrated nutrition interventions in Uganda
REFNo: HS1549ES

1. Evaluate the program design, selected nutrition, and health outcomes among women and children under 5 years at baseline and at the end of the Community Connector interventions.
2. Explore the experiences of the implementers and the beneficiaries of the Community Connector interventions.
3. Evaluate the effectiveness of the Community Connector interventions on nutrition and health outcomes among women and children under 5 years.
4. Develop and validate a framework for improving effectiveness of integrated nutrition interventions for implementation in resource-poor settings.

Uganda 2021-07-28 2024-07-28 Medical and Health Sciences Non-Clinical Trial Degree Award
Lore Vandewalle
ID: UNCST-2021-R014028
 Small Firm Diaries with carpenters in Uganda
REFNo: SS919ES

The main objective of this research is to understand the frictions in the market for outputs that hamper the growth of small-scale carpenters in Uganda. We will write a descriptive paper that outlines the frictions we observed. Given the large number of programs targeting MSMEs to foster employment growth in low-income countries, the recommendations that will emerge from our project will be useful to policy makers operating at local, national and supra-national levels. The second objective is designing an intervention tailored to remove the most important friction we observed in the market for outputs. We will test this intervention using a randomized control trial and will estimate its causal effect on the growth of small-scale carpenters. Growth will be measured through changes in revenues, profits, productivity and employment. This should be informative to both academics and policy makers as well. The intervention is not yet defined, as we want to use the data to identify the most prominent friction in the market for outputs that limits the growth of carpenters. We will request an amendment to this IRB as soon as it has been designed. The final objective is assembling unique data on small-scale carpenters in Uganda. As detailed in the methodology subsection below, we will create two unique panels that will allow us to map a complete, real-time characterization of the performance of small enterprises, decision-making and shock responses of entrepreneurs, inputs’ usage and business relationships, including partner-specific trade interactions. These datasets are instrumental to accomplish the first two objectives: it provides the information needed to understand the frictions in the markets for outputs (main objective) and to define the intervention (objective 2). We list the datasets as a separate objective, as these will become public and can thus be used by policy makers, other researchers and students as well.
Belgium 2021-07-27 2024-07-27 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ronald Twongyirwe
ID:
Analysis of past and projected future land use change and its impact on sediment fluxes in the Rwizi catchment
REFNo: NS147ES

. Firstly, the project aims at strengthening the academic research capacity at the universities of Mbarara and Gulu (Uganda) by means of the training of two PhD-researchers and several postdoctoral researchers in the field of integrated watershed management. Secondly, the project will develop fundamental research on the, hitherto largely overlooked, coupling between demographic developments on the one hand, and the degradation of soil and water resources on the other hand. Thirdly, the results from this fundamental research will be translated into landscape transformation models that will allow land managers and policymakers to evaluate alternative devel-opment pathways for the catchment.
Uganda 2021-07-26 2024-07-26 Natural Sciences Degree Award
SHANI BUDIGOLI DEODATUS
ID:
Prevalence, clinical manifestations, relationship with viral load of cutaneous disorders among children and adolescents living with HIV attending Mbarara Regional Referral Hospital.
REFNo: HS1265ES

1. To determine the prevalence of cutaneous disorders among children and adolescents living with HIV attending pediatric infectious Diseases' clinic at MRRH.
2. To describe the clinical manifestations of cutaneous disorders among children and adolescents living with HIV attending paediatric infectious Diseases’ clinic at MRRH.
3. To determine the relationship of cutaneous disorders and viral load among children and adolescents living with HIV attending pediatric infectious Diseases’ clinic at MRRH.
4. To assess the relationship between cutaneous disorders and CD4 counts among children and adolescents living with HIV attending pediatric infectious Diseases’ clinic at MRRH.



 Tanzania 2021-07-26 2024-07-26 Medical and Health Sciences Degree Award
Timothy Kiyemba
ID:
Protocol for conducting the beneficiary survey for the USAID Defeat TB project.
REFNo: HS1518ES

The purpose of this beneficiary survey is to assess the results of project implementation with regard to health workers, TB patients and the general community after 3 years of activity implementation in Kampala, Wakiso and Mukono districts.
 Uganda 2021-07-26 2024-07-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Brenda  Boonabaana
ID:
Developing and displacing the 21st century city: mapping the spatial strategies and impacts of global retail investment
REFNo: SS916ES

1.To understand the geographic contexts of global retail capital investment; 2. To trace and understand its geographic transformations; 3. To understand and create grounded and sustainable responses.
Uganda 2021-07-26 2024-07-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Samuel Kabwigu
ID: UNCST-2020-R014735
 ENHANCING UNDERSTANDING OF ADOLESCENT PREGNANCY IN UGANDA: TOWARDS FUTURE IMPLEMENTATION
REFNo: HS859ES

1. Examine how familial relationships influence adolescent pregnancy in Luuka district.
2. Explore factors in the community, (such as ICTS, policies and regulation, or health services) that influence adolescent pregnancies in Luuka District.
3. Assess ways of enhancing familial relationships as a meditative approach that will reduce rates of adolescent pregnancies in Luuka district.

 Uganda 2021-07-23 2024-07-23 Medical and Health Sciences Non-Clinical Trial Degree Award
Rottenberg Esther Sophia
ID:
Making evidence on antimicrobial resistance: a historical and ethnographic study across the UK and Uganda
REFNo: SS622ES

To show how evidence on antimicrobial resistance is produced with the help of a model.
2) To understand how the context of Hoima shapes the production of knowledge on antimicrobial resistance.
3) To investigate the negotiations taking place within the context of a transnational, interdisciplinary research collaboration.
Germany 2021-07-22 2024-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
Jonathan Kajjimu
ID: UNCST-2021-R013696
 MATERNITY CARE FOR WOMEN REFUGEES FROM NAKIVALE REFUGEE RESETTLEMENT: A NEEDS ASSESSMENT
REFNo: SS874ES

1. To determine the socio-demographic characteristics of pregnant refugee women and recently delivered refugee mothers from Nakivale refugee settlement. 2. To describe the experiences of pre-pregnancy, pregnancy, childbirth, postnatal periods, and maternity services available to refugee pregnant women and newly delivered refugee mothers from Nakivale. 3. To identify gaps in maternity care delivered to refugee pregnant women and newly delivered refugee mothers from Nakivale refugee settlement. 4. To acquire opinions of maternity services providers, and refugee pregnant women, and newly delivered refugee mothers from Nakivale refugee settlement on how to improve the refugee pregnancy outcomes.
Uganda 2021-07-22 2024-07-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Katherine Fiorillo Fiorillo
ID:
Measuring Women's Empowerment in Agroforestry Activities in Northern Uganda
REFNo: SS799ES

Research Questions:

● What is the baseline level of women’s empowerment in agroforestry in the project target area?
● How can project activities better address issues of women’s empowerment in agroforestry in the target area?
The main objectives of this research study, listed above, are to understand the baseline level of women’s empowerment and how the project can better respond to these issues. The baseline will be used to both inform and to monitor the project progress towards women’s empowerment. A strong evidence base will allow Kijani to adapt programming to better meet the needs of the community. Qualitative protocols will ensure that the community’s needs and values are being expressed fully in the research process.

USA 2021-07-22 2024-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
Alex Bakenga
ID: UNCST-2021-R014039
 Outcomes of treatment with ADT and chemotherapy in patients with metastatic prostate cancer at the Uganda cancer institute
REFNo: HS1542ES

Objective 1: To describe the biochemical response (TPSA) of patients with metastatic prostate cancer treated with ADT and chemotherapy at the Uganda cancer institute. Objective 2: To determine the 1, 3 and 5-year survival among patients with metastatic prostate cancer treated with ADT and chemotherapy at the Uganda cancer institute. Objective 3: To determine predictors of 1, 3 and 5-year survival among patients with metastatic prostate cancer treated with ADT and chemotherapy at the Uganda cancer institute.
Uganda 2021-07-22 2024-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
SARAH NAWOOVA
ID:
COACHING AND LECTURERS' SUPERVISION SKILLS IN NATIONAL TEACHERS' COLLEGES IN UGANDA
REFNo: SS891ES

1. TO EXAMINE THE RELATIONSHIP BETWEEN COACHING AND LECTURERS' REFLECTIVE QUESTIONING SKILLS.
1.TO EXAMINE THE RELATIONSHIP BETWEEN COACHING AND LECTURERS' OBSERVATION SKILLS.
3.TO EXAMINE THE RELATIONSHIP BETWEEN COACHING AND LECTURERS' FEED BACKING SKILLS.

 Uganda 2021-07-22 2024-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
Benon Asiimwe Byamugisha
ID:
COVID-19 and Antimicrobial Resistance in East Africa: impact and response (CARE)
REFNo: HS1519ES

To establish how community members have received and responded to health messages on COVID-19,To examine how the COVID-19 crisis is affecting patient treatment seeking, drug use, and understanding of illness, and how this is affecting the wider landscape of AMR,To the establish antibiotic provision landscape from the perspective of drug sellers, pharmacists, traditional medicine providers, and formal healthcare workers,To investigate how COVID-19 may be modifying patients’ treatment seeking behaviour, their usage of medicines/ABs and affecting access to and provision of ABs in the therapy landscape in Uganda,
 Uganda 2021-07-22 2024-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mauro Giacomazzi
ID:
Effectiveness of the Whole School System Approach in Fostering Critical Thinking among Learners in Ugandan Secondary Schools
REFNo: SS931ES

Main objective To investigate how the whole school system approach to critical thinking contributes to the development of leaners’ cognitive abilities in Ugandan secondary schools. Specific objectives (i) To establish the meaning of critical thinking in the Ugandan context. (ii) To explore how teachers can improve their teaching and learning through the critical thinking activation approach. (iii) To explore how critical thinking can be appropriately assessed in the Ugandan secondary school context. (iv) To establish the extent to which the whole school system approach contributes to the development of critical thinking abilities of Ugandan secondary school learners. (v) To establish individual, school and home related factors that influence critical thinking abilities of Ugandan secondary school learners. (vi) To explore the strategies that Ugandan secondary school teachers use in preparing and delivering critical thinking augmented lessons.
 Italy 2021-07-22 2024-07-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Robert Opika Opoka
ID: UNCST-2021-R014036
 The role of prolonged exposure to parasitemia in the high morbidity in children with Sickle cell anaemia in Uganda
REFNo: HS1496ES

Primary Aims
1. To determine the rate of parasite clearance during artesunate therapy in children with sickle cell anaemia compared to children without SCA.
We hypothesize that children with SCA will experience parasite clearance half-life times exceeding the WHO-defined standard of 5 hours when treated with artemisinins for P. falciparum malaria, whereas children without SCA will not experience this delayed parasite clearance.

2. To determine the association between parasite clearance rate and risk of vaso-occlusive crisis, severe anaemia, and any hospitalisation in children with SCA.
We hypothesize that prolonged parasite clearance will correlate with increased risk of SCA-related sequelae.

3. To determine the association between kidney and splenic function and parasite clearance half-life during artesunate treatment for malaria.
We hypothesize that impaired renal function (estimated creatinine clearance) and splenic function (presence of Howell-Jolly bodies) will correlate with increased parasite clearance half-life.

Secondary Aims
1. To determine the incidence of treatment failure (new clinical malaria within a 28-day follow-up period after microscopy-confirmed parasite clearance) after artemisinin combination therapy for malaria
2. To detect and measure the prevalence of parasite genetic markers of artemisinin resistance in Jinja

 Uganda 2021-07-21 2024-07-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
James Nyonyintono Mwangwa
ID: UNCST-2023-R005636
 Feasibility of Use of the PATH bCPAP Kit including Oxygen Blenders in a Neonatal Population in Uganda
REFNo: HS650ES

Primary Objectives: 1. To assess the operational feasibility of using the PATH bCPAP kit including, when appropriate, in-line oxygen blending on neonatal patients. 2. To assess the usability and acceptability of the PATH bCPAP kit with oxygen blenders by healthcare workers. Secondary Objective: 1. To report clinical characteristics, demographics and outcomes of patients treated with the PATH bCPAP kit and blenders in a newborn care unit in rural Uganda.
 Uganda 2021-07-19 2024-07-19 Medical and Health Sciences Non-degree Award
Esther Buregyeya
ID: UNCST-2020-R014116
 Using a behavioural approach to design an antimicrobial stewardship intervention in healthcare facilities in Kampala, Mukono and Luwero Districts, Uganda
REFNo: HS1303ES

1. To explore the barriers to and facilitators for rational use of antibiotics and setting up AMS programs in HCFs in Uganda.
2. To develop, pilot an AMS behavioural intervention and assess its acceptability, feasibility and effect to foster appropriate antibiotic prescription in HCFs in Uganda.
3. To assess the cost of the intervention in fostering rational use of antibiotics in Uganda.

 Uganda 2021-07-16 2024-07-16 Medical and Health Sciences Non-degree Award
Shevin  Jacob Thomas
ID:
AN OBSERVATIONAL STUDY TO ASSESS THE UTILITY OF BEDSIDE ULTRASOUND SCAN IN SEPSIS TREATMENT AMONG HOSPITALIZED ADULTS IN UGANDA
REFNo: HS1499ES

General objective: To describe the potential utility of bedside ultrasound scanning in evaluating adult patients with suspected sepsis admitted to hospitals in Uganda Specific objectives: 1. Estimate the proportion of patients admitted to the medical emergency unit with suspected sepsis who have ultrasound findings consistent with intravascular fluid depletion. 2. Estimate the proportion of patients admitted to the medical emergency unit with suspected sepsis who have ultrasound findings suggestive of intolerance to high volume intravenous fluid. 3. Estimate the proportion of patients admitted to the medical emergency unit with suspected sepsis who have ultrasound findings that identify a potential source of infection. 4. Determine the feasibility of delivering POCUS to evaluate non-pregnant adult patients with sepsis by clinicians who are not specialized in radiology.
USA 2021-07-16 2024-07-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Conrad Muzoora Kihembe
ID: UNCST-2019-R001432
 Determination of Adequate TUberculosis Regimen in Adults and adolescents hospitalised with HIV-associated severe immune suppression (Acronym: DATURA).
REFNo: HS1487ES

Primary objective: To estimate the impact of an intensified initial phase of tuberculosis (TB) treatment on mortality at 48 weeks among HIV-infected adults and adolescents hospitalised for TB with CD4 ≤ 100 cells/μL in comparison with the standard TB regimen. Secondary objectives: To estimate the impact of an intensified initial phase of TB treatment, in comparison with the standard TB regimen, on: ¥ Mortality at weeks 8 and 24 ¥ Adverse events, including: - All grade 3-4 events - Selected grade 2 events of interest - Drug-related adverse events - AIDS defining illnesses - Paradoxical TB-associated immune reconstitution inflammatory syndrome (IRIS) ¥ TB treatment success ¥ TB recurrence ¥ Antiretroviral treatment (ART) response in terms of virological success and immunological response ¥ Adherence to TB treatment and ART ¥ Peak plasma concentrations of rifampicin and isoniazid (and its N-acetyl-metabolite) at day 3, day 7 and week. ¥ Plasma concentrations of efavirenz and dolutegravir at week 4 (i.e. 2 weeks after the onset of ART)
Uganda 2021-07-16 2024-07-16 Medical and Health Sciences Clinical Trial Non-degree Award
Davis Ntulume Roland
ID:
A Cross Sectional Study on Exploring the Lifestyle of Makerere University Staff With an Aim of developing a Bespoke Healthy Living Program for people in Academia
REFNo: HS1500ES

Our main goal is to identify and understand the key factors that attribute a typical working day of Makerere University and inhibitors of following a heathy living programme and use this feedback
10
to design a contextually appropriate and bespoke programme for adoption in the field of academia and other sectors at large. This will be achieved in the following sub aims:
1. To establish the dietary and physical activity patterns of overweight and obese staff at Makerere University College of Health Sciences staff.
2. To support overweight and obese individuals to adopt an energy restricted diet and weekly physical exercise while establishing the behavioural and social determinants of compliance to the programme.
3. To establish the effect of change on food and activity body weight and health status and recommend a bespoke healthy living programme that puts into consideration the routine, perceptions and inhibitors to living a healthy lifestyle that works for Academic staff nationwide.
 Uganda 2021-07-16 2024-07-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jude Ssempebwa
ID:
COVID-19 and the Youth Question in Africa: Piloting a Vertically Integrated Social Accountability and Advocacy Framework in the IGAD Region (COYOQA)
REFNo: SS921ES

1. To carry out a comprehensive gender analysis of the current social mobilization of youth in informing, co-designing and supporting COVID-19 pandemic emergency preparedness and response, capacity, key gaps and support needs among IGAD Member States (Ethiopia, Kenya and Uganda).
2. To build the capacity of male and female Youth Volunteers for Behavior Change (YOV4BC) in emergency preparedness, response (disaster risk reduction and management) and building resilience to impacts of COVID-19 so that they are well informed, resourced and educated about COVID-19 and its prevention measures.
3. To partner with the youth to take action within their communities through developing and institutionalizing a standardized and harmonized COVID-19 Vertically Integrated Social Accountability and Advocacy Framework for monitoring the IGAD Regional Response Strategy(IRRS) for COVID-19 Pandemic in Kenya, Uganda and Ethiopia.
4. To investigate and track gender differentiated sectoral socio-economic impacts of COVID-19 on youth and their communities and document community perceptions and response strategies.
5. To facilitate meaningful policy engagement between male and female youth and policy makers through enhanced national, sub-national and regional knowledge sharing platforms.

 Uganda 2021-07-16 2024-07-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
Roselline Achola
ID:
Decision making about Family Planning use by refugee and host populations in Adjumani district, Uganda
REFNo: SS809ES

1.To explore decision making processes for FP use by refugee and host population in Adjumani district
2.To establish factors associated with FP use by women and men in the refugee and host populations in Adjumani
3.To develop and evaluate an intervention to increase FP use by refugee and host populations

Uganda 2021-07-15 2024-07-15 Social Science and Humanities Non-Clinical Trial Degree Award
Richard Munana
ID:
Chronic Kidney Disease among Patients with Diabetes and Hypertension in Nakaseke District Rural Uganda: Assessing Patient Characteristics and the Diagnostic Performance of Saliva Urea Nitrogen Strips in Chronic Kidney Disease Diagnosis When Combined with a Chronic Kidney Disease Case Finding Questionnaire and Machine Learning.
REFNo: HS1387ES

1) To determine the diagnostic performance of Saliva Urea Nitrogen (SUN) strips when combined with a chronic kidney disease case-finding questionnaires and machine learning in the diagnosis of chronic kidney diseases among patients with diabetes and or hypertension in Nakaseke district, rural Uganda. 2)To establish a Chronic Kidney Disease patients’ cohort based in the Rural Uganda Non-Communicable Disease (RUNCD) Cohort in Nakaseke, Uganda.
 Uganda 2021-07-15 2024-07-15 Medical and Health Sciences Non-Clinical Trial Degree Award
Betty OKOT
ID: UNCST-2021-R013938
 Echoes of Antiquity in Acholiland: The Return to Te-Kwaro (Tradition) after the Civil War in Northern Uganda: RefNo:GUREC-2021-57
REFNo: SS833ES

ii. Highlight how memories, practices and unwritten laws reinforce land rights through links and attachment to the past actively conveyed in return migrations; ,3.Examine the roles and disputed effectiveness of traditional chiefs as latter-day custodians of traditional laws in modern times.,1. Recapture and retell the past through specific stories of return to abandoned homesteads ,
 Uganda 2021-07-15 2024-07-15 Social Science and Humanities Non-Clinical Trial Non-degree Award
Charles Kiyaga
ID:
Establishing universal screening and early interventions for SCD within the selected clinical networks for prevention of early mortality in Uganda.
REFNo: HS1362ES

Primary Objectives

a)To pilot newborn screening for SCD within the clinical networks of Jinja and Lira regional referral hospital in Uganda.

b)To register patient data and medical history of babies diagnosed with SCD within the first three months of life in a shared database.

c)To initiate antibacterial and antimalarial prophylaxis among the identified SCD infants within the first three months of life.

d)To ensure that the identified SCD infants are each immunized against pneumococcus and Haemophilus influenzae type b.

e)To monitor each patient at required intervals (every three months until age two years; every four to six months from age three to five years) and update patient record in registry after each visit.

f)To estimate the incidence of SCD among infants and children identified in Jinja and Lira regional referral hospitals and identify the specific hemoglobin genotypes.

Secondary Objectives

a)To measure the 5-year survival rate of children enrolled in the newborn screening cohorts.

b)To assess the costs of newborn screening and early interventions for each site or network

 Uganda 2021-07-14 2024-07-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan Babirye
ID: UNCST-2021-R013201
 Using realist evaluation principles to explore existing local innovations for improving timely attendance of first antenatal care among slum dwellers of Kampala, Uganda
REFNo: SS869ES

1) To identify the existing local innovations for increasing timely attendance of first antenatal care visit and their perceived success.
2) To describe the theories of change for the innovations perceived to be successful at increasing timely attendance of first antenatal care visit.
3) To explore the underlying mechanisms (generalizable contextual factors) that favored success of innovations perceived to be successful at increasing timely attendance of first antenatal care visit among slum dwellers.

Uganda 2021-07-14 2024-07-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
Naome Wandera Namakula
ID:
Assessing the effectiveness of a course for men on Women’s Land Rights Social Norms in Kenya, Tanzania and Uganda- Endline Assessment in Uganda
REFNo: SS889ES

To document the current status of knowledge, attitudes, self-efficacy, intentions and perceptions of peer norms related to women’s land and property rights among men that participated in the SYFF course in Kenya and Uganda. The changes at end-line, if any, in knowledge, attitudes, self-efficacy, intentions and perceptions of peer norms related to women’s land and property rights among participants in the SYFF course in each country will be compared to baseline status.
 Uganda 2021-07-14 2024-07-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
Janet SEELEY
ID:
Menstrual health interventions, schooling and mental health symptoms among Ugandan students (MENISCUS): a school-based cluster-randomised trial.
REFNo: HS1525ES

1. To evaluate whether the MENISCUS intervention improves educational attainment and reduces mental health symptoms (primary outcomes) among Secondary girls in Uganda.

2. To evaluate whether the MENISCUS intervention improves: i) knowledge of puberty and menstruation; attitudes towards menstruation (girls and boys); ii) menstrual practices at last menstrual period (LMP); iii) knowledge and practice of pain management during LMP; iv) self-efficacy in addressing menstrual needs experiences at LMP; v) quality of life and happiness; vi) school and class absence during menses (nested cohort); vii) school and class absence overall (nested cohort); viii) prevalence of urogenital infections (bacterial vaginosis, vaginal yeast and urinary tract infections)
3. To evaluate the costs of setting up and running the intervention package, the unit cost per female student reached, and the incremental cost-effectiveness of the intervention per unit increase in selected policy-relevant outcomes, relative to optimised usual care
4. To assess whether the intervention was implemented with fidelity, and to understand the contextual factors affecting implementation, the acceptability to participants, and the intervention mechanisms. We will achieve this through a process evaluation including quantitative indicators and qualitative data collected from in-depth interviews and focus group discussions.
5. To assess the policy environment around menstrual health in Uganda, focusing on how implementing the intervention contributes to, and aligns with, the attainment of the Government policy objectives on menstruation management in schools. We will assess the policy/regulatory frameworks to which the outcomes of the intervention contribute, identify the supportive and constraining factors to the implementation of the policy guidelines and how the findings of the intervention inform refinement of current policy.

 UK 2021-07-14 2024-07-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Damalie Nakanjako
ID: UNCST-2019-R000383
 Mobile Phone-based patient follow-up Package with Medical Intervention for HIV-infected adults to promote social distancing during and after the COVID19 pandemic lockdown crisis
REFNo: HS945ES

Objectives
1.To pilot use of a Mobile Phone-based patient follow-up Package with virtual Medical Interventions (PMI) among adults receiving antiretroviral therapy (ART) at the Mulago ISS clinic.
2.To determine the effect of a PMI on the number of physical clinical visits by patients receiving ART at the Mulago ISS clinic during the one-year study period.
3.To determine the effect of PMI on continuity of ART medication during the COVID19 pandemic crisis period.
4.To determine the acceptability of the PMI approach to follow up of patients receiving long-term ART by patients and care providers at the Mulago ISS clinic

Uganda 2021-07-13 2024-07-13 Medical and Health Sciences Non-degree Award
Christina Bergey Marie
ID: UNCST-2020-R014338
 Genetic survey of bloodborne pathogens and investigation of malaria response in sanctuary chimpanzees
REFNo: NS139ES

Our proposed study has three main objectives:

1. To determine which blood-borne pathogens sanctuary chimpanzees carry, with a particular interest in those which can be transmitted from human to chimpanzee (anthroponoses) and vice versa (zoonoses);

2. To diagnose malaria infection in sanctuary chimpanzees and determine which malaria parasite species are present, with a particular interest in human malaria that may be infecting the chimpanzees; and

3. To describe the genetic mechanisms underlying the chimpanzee immune system response to malaria, and contrast this with that of humans.
 USA 2021-07-13 2024-07-13 Natural Sciences Non-degree Award
Anthony  Fuller
ID:
Assessment of Accuracy, Precision, and Feasibility of a Handheld Near-Infrared Light Device (InfraScanner 2000â„¢) in Detecting Subdural and Epidural Hematomas in Patients Admitted to Mbarara Regional Referral Hospital
REFNo: HS1010ES

Aim 1: Determine whether the InfraScanner 2000â„¢ detects epidural and/or subdural hematomas with adequate precision relative to CT scans to be used as a diagnostic tool for epidural and/or subdural hematomas.

Aim 2: Use these findings to inform the feasibility of conducting a future trial in which the InfraScanner 2000â„¢ is used as a stand-alone diagnostic tool for intracranial hematomas, and therein, to determine candidacy for decompressive craniotomies in patients who suffer TBIs in places where CT scans are not available.
 USA 2021-07-13 2024-07-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Vittorio Bassi
ID:
Covid-19 and the value of relationships in informal economies
REFNo: SS633ES

The overall goal of the study is to implement two exploratory phone surveys of a representative sample of Micro, Small and Medium enterprises (MSMEs) and their employees in Uganda. The survey is designed to document challenges firms are facing in investing and hiring workers during the covid-19 pandemic. In addition, the first phone survey will also embed a nudging experiment aimed at helping workers search for jobs and regain employment in the wake of the pandemic. This is an urgent study that forms a continued commitment of the researchers under BRAC Uganda partnership with Ministry of Trade, Industry and Cooperatives under Directorate of Micro and Small Medium Enterprises (MSMEs) to provide insights and learning on how the covid-19 shock has affected firm owners and employees’ relationships during the lockdown.
 Italy 2021-07-13 2024-07-13 Social Science and Humanities Non-degree Award
Ismay Milford Milford
ID:
The ‘Information Sector’ in East Africa, 1950s-70s: The professionalisation of journalism, broadcasting and information officers
REFNo: SS730ES

This project is a history of the ‘information sector’ as it emerged in dialogue with global patterns over the period of decolonisation in East Africa (c. 1950s-70s). I understand information not as a given technology inevitable to the language of the developmentalist state in mid-twentieth century Africa, but as a culturally constructed and moulded idea through which we can access connections that East African people of various ‘information professions’ forged with the wider world. This is in some sense a pre-history of the global debates around information that resulted in the call for a ‘New World Information and Communication Order’ in the 1970s. It argues that East Africa played an important role in the disciplinary shift from ‘information science’ to ‘mass communication’, and in the understandings of knowledge production that informed postcolonial theory.
UK 2021-07-13 2024-07-13 Social Science and Humanities Non-degree Award
Pierre ABOMO
ID:
Strengthening national capacity for tsetse control in Uganda
REFNo: SS725ES

1) Conduct semi-structured interviews with key personnel at COCTU and the District level to fully understand the current level of execution of the action plan for strengthening the capacity to for implementing tsetse control in Uganda

2) Conduct participatory workshops at COCTU and the District level to collaboratively assess the progress towards the establishment of a stronger and independent tsetse control system in Uganda (based on findings from objective 1).
UK 2021-07-13 2024-07-13 Social Science and Humanities Non-degree Award
Eddie Wampande Mujjwiga
ID:
An evaluation of African swine fever presentation and distribution in Uganda
REFNo: NS266ES

i. Conduct a serologic, clinical, pathological, and molecular diagnostic survey of swine at a large slaughterhouse near Entebbe and Kampala, Uganda to understand the relationship between the disease status and the diagnostic status of the animals as related to Africa swine fever.
ii. Conduct a serologic analysis slaughterhouse swine to measure the immune response against exposure to the Ornithodoros moubata tick, the ASF reservoir vector in Africa.
iii. Conduct trace back to hotspots to evaluate biosecurity and conduct training of veterinarians and producers on the clinical and pathological signs of Africa swine fever.
iv. Sequence PCR positive samples to better characterize the ASF genotype and strain and its disease presentation.
v. Discuss the findings with the Ministry of Agriculture, Animal Industries, and Fisheries.

 Uganda 2021-07-13 2024-07-13 Natural Sciences Non-degree Award
Charles Batte
ID: UNCST-2021-R013587
 ASSESSING THE SOCIO-ECONOMIC IMPACT OF COVID-19 PANDEMIC ON SMALLHOLDER FARMERS’ HOUSEHOLDS AND SCHOOL-GOING CHILDREN IN BUDUDA DISTRICT, UGANDA.
REFNo: SS789ES

To assess the impact of the COVID-19 pandemic on school-going children in Bududa district.,To assess the socio-economic impact of the COVID-19 pandemic on smallholder farmers’ households in Bududa district.,
 Uganda 2021-07-13 2024-07-13 Social Science and Humanities Non-degree Award
omia Obel Francis Patrick
ID:
MULTI-STAKEHOLDER PARTICIPATION IN NATIONAL BUDGETING IN UGANDA By Francis Patrick Omia
REFNo: SS870ES

The purpose of this study is to assess the effect of multi-stakeholder participation in national budget preparation
The specific objectives of the study are as follows;
1. To examine mechanisms for Multi-stakeholder participation in budget preparation planning.
2. To analyze Multi-stakeholder participation in budget deliberation.
3. To assess Multi-stakeholder participation in budget preparation outcomes.

Uganda 2021-07-13 2024-07-13 Social Science and Humanities Non-Clinical Trial Degree Award
Nitin Wadhwa
ID:
Investigating crop raiding and ranging of habituated mountain gorillas close to park boundaries in the Buhoma sector of Bwindi National Park, Uganda.
REFNo: NS263ES

1. In this proposed study, we will walk jungle trails taken by forest rangers in the Buhoma sector to find and map signs of gorilla presence and human related activity. 2. Based on the spatial mapping exercise and density of recorded signs in a particular area, we will identify areas of high gorilla movement and ascertain how close to park boundaries gorillas are venturing and also how high are disturbance factors like human activity along the boundaries of the park. 3. We will also walk and survey the approximately 10 kms of park boundary relevant to our study (See Figure 3 in Appendix) in the Buhoma sector to map land use and cropping pattern along the edges of park (upto 150 metres). 4. Based on the the survey excersise along the boundaries of the park, we will map the land use patters and crops planted along the boundaries to create a spatial map to understand human activities along the edge park. 5. We will use data obtained from previous objectives and extrapolating it in conjunction with already existing research, we will draw conclusions and give recommendations.
India 2021-07-13 2024-07-13 Natural Sciences Non-Clinical Trial Non-degree Award
Eve  Namisango
ID: UNCST-2021-R014038
 Mapping service pathways across the cancer disease trajectory in Kampala; a retrospective cohort study of timing and access to services
REFNo: HS805ES

1. To determine the number of patients accessing cancer services at Uganda Cancer Institute, Mulago Palliative care Unit, Kawempe Home Care and Hospice Africa Uganda from 2018 across 2019
2. To Identify source of referrals and target of onward referrals across these above services
3. To determine case mix across cancer services
4. To determine median number of days between referral to cancer care services and death for the study sample
5. To Identify variation in access to and referrals to cancer services by sex, age, ethnicity, diagnosis, and geographical location of residence
6. To Depict cancer pathway for patients from diagnosis to death in Kampala, Uganda

Uganda 2021-07-12 2024-07-12 Medical and Health Sciences Non-degree Award
Franklin Higenyi
ID:
Gender and Public Health Space:A case of Female Doctor's career progression in Uganda Public Medical Services
REFNo: SS732ES

The study will investigate the factors that determine FDs’ career progression in UPMS.
1.4.1. Specific Objectives
1.4.1.1. To assess gender differences in career progression of female and male doctors in UPMS.
1.4.1.2. To analyze the socio-cultural and institutional factors that influence career progression of FDs in UPMS space.
1.4.1.3. To asses lived experiences of those who have managed to have career progression.
 Uganda 2021-07-12 2024-07-12 Social Science and Humanities Degree Award
Cosmas Mwikirize
ID:
Efficacy of a Deep Learning-aided Platform for Diagnosis of Breast Cancer using Ultrasound Images in the Ugandan Population
REFNo: SIR57ES

General Objective: To develop and evaluate the efficacy of a deep learning-based computer-aided platform for screening of breast cancer in the Ugandan population. Specific Objectives: 1. To collect, and curate and label breast US data from ECUREI Radiology department. 2. To develop deep learning models for lesion detection and pixel-wise segmentation in breast US images. 3. To integrate the learned models in an offline computer-aided detection platform for breast cancer, and clinically evaluate its performance. 4. To develop and integrate learned models for breast cancer detection, in a real-time portable ultrasound imaging platform.
Uganda 2021-07-12 2024-07-12 Engineering and Technology Non-degree Award
Onesmus  Ahabwe Magezi
ID:
COMMON CAUSES OF ABNORMAL VAGINAL DISCHARGE AND ANTIBIOTIC SUSCEPTIBILITY AMONG WOMEN ATTENDING THE GYGAECOLOGICAL OUTPATIENT CLINIC OF MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS1456ES

1.To determine the common bacterial isolates among women with abnormal vaginal discharge attending the gynecological outpatient clinic of Mbarara Regional Referral Hospital.
2.To describe the antibiotic susceptibility patterns of bacterial isolates among women with abnormal vaginal discharge attending the gynecological clinic of Mbarara Regional Referral Hospital.
3.To identify the factors associated with antibiotic resistance to commonly used antibiotics among women with abnormal vaginal discharge attending the gynecological outpatient clinic of Mbarara Regional Referral Hospital

 Uganda 2021-07-12 2024-07-12 Medical and Health Sciences Non-Clinical Trial Degree Award
Josylin Ekochu Arimpa Bananuka
ID:
Corporate Governance Practices and Performance of Pharmaceutical Manufacturing Firms in Uganda
REFNo: SS571ES

i. To analyze the effect of corporate leadership on the performance of pharmaceutical manufacturing firms in Uganda
ii. To assess the effect of boards of directors on the performance of pharmaceutical manufacturing firms in Uganda
iii. To investigate the consequences internal control systems have on the performance of pharmaceutical manufacturing firms in Uganda

Uganda 2021-07-09 2024-07-09 Social Science and Humanities Degree Award
Francis Ocheng
ID:
Helichrysum odoratissimum: Isolation and identification of bioactive compounds and their effects on oral bacteria
REFNo: HS1441ES

2-To determine whether the isolated and purified compounds from Helichrysum odoratissimum maintain their antibacterial effects on oral bacteria,1-To isolate and identify the bioactive compounds in the plant Helichrysum odoratissimum plant extracts ,The general objective of the study is to isolate and identify the bioactive compounds in the Helichrysum odoratissimum plant extracts and also further investigate the effects of the isolated compounds on oral bacteria ,
 Uganda 2021-07-09 2024-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Catriona  Waitt John
ID: UNCST-2019-R001068
 Implementation of a "bundle of care" to improve anticoagulation control in patients receiving warfarin in Uganda and South Africa
REFNo: HS1422ES

Primary objective is to evaluate whether implementation of warfarin bundle improves time in therapeutic range

Secondary objectives are:
-To evaluate whether implementation of the warfarin bundle improves time to achieving a therapeutic INR
-Whether implementation of the warfarin bundle affects the occurrence of adverse events(death, bleeding and thrombotic events)
-whether staff find the interventions contained in the bundle acceptable
-To explore patients' experiences and acceptability of the package of care, and
-Whether the bundle represents good value for money
 UK 2021-07-09 2024-07-09 Medical and Health Sciences Clinical Trial Non-degree Award
Maureen Ayikoru
ID:
REVISED PROPOSAL IN RESPONSE TO THE OUTCOME OF ROUND 1 OF COMMITTEE REVIEW OF THE PROJECT “INDIRECT IMPACTS OF COVID-19 ON HEALTHCARE SYSTEMS: A CASE STUDY OF UGANDA’S HEALTHCARE PROFESSIONALS”
REFNo: HS1524ES

To document what lessons can be learnt from Uganda’s response to COVID-19,To analyse the impact of information and communication technologies and the media, including digital, print and broadcast media in containing the COVID-19 pandemic in Uganda.,To analyse what if any, political economy factors influence misinformation, resource reallocation and prioritisation during the ongoing pandemic and to document the perceived effects on the entire healthcare system including those most vulnerable,To identify what threats COVID-19 has had on physical, psychosocial, and overall well being of HCPs and to assess what if any formal and informal coping mechanisms have so far been available to them,To generate empirical evidence on the indirect impacts of Uganda’s response to COVID-19, focusing on the healthcare professionals.,
 Uganda 2021-07-09 2024-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Adoke Yeka
ID: UNCST-2021-R004300
 Efficacy and safety of artemether-lumefantrine, pyronaridine-artesunate, artesunate-amodiaquine and dihydroartemisinin – piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in Uganda.
REFNo: HS1363ES

The general objective of this study is to assess the therapeutic efficacy and safety of artemether-lumefantrine (AL), pyronaridine-artesunate (PA), artesunate-amodiaquine (ASAQ) and dihydroartemisinin-piperaquine (DP) for the treatment of uncomplicated P. falciparum malaria in three sentinel sites in Uganda.
The primary objectives are:
• to measure the clinical and parasitological efficacy of 4 artemisinin-based combination therapies (ACT), artemether-lumefantrine (AL) Pyronaridine-artesunate (PA), artesunate-amodiaquine (ASAQ) and dihydroartemisinin-piperaquine (DP).
• to differentiate recrudescence from new infection of Plasmodium falciparum by molecular techniques.
The secondary objectives are:
• to evaluate the incidence of adverse events; and
• to determine the polymorphism of molecular markers mediating resistance for Artemsinin, Pyronaridine, Piperaquine and Lumefantrine resistance.
• to determine the blood concentration of Lumefantrine after treatment with Artemether- Lumefantrine .


 Uganda 2021-07-08 2024-07-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Aubryn Sidle Allyn
ID:
Emplacing Agency in Girls' Education Practice: An Evaluation of Impact
REFNo: SS651ES

1. To evaluate the impact of CDOs’ programs on girls' Agency outcomes.
2. To understand how and why programs influence agency in adolescent girls, and what aspects of program design impede or speed this development.
3. To understand the relationship between girls’ agency and educational outcomes.
4. To evaluate the relationship between girls’ agency and teenage pregnancy incidence and determine what effect, if any, increased agency has on teenage pregnancy.
 USA 2021-07-07 2024-07-07 Social Science and Humanities Degree Award
Angelique Murorunkwere
ID:
DIAGNOSTIC DELAY AND ITS CAUSES AMONG PEDIATRIC CANCER PATIENTS AT MBARARA REGIONAL REFERRAL HOSPITAL CANCER UNIT
REFNo: SS857ES

1. To determine the average time between onset
of symptoms and diagnosis among children
with cancer at MRRH
2. To outline caregiver self-reported reasons
for delayed diagnosis among children with
cancer at MRRH
3. To establish the correlates of delayed
diagnosis among children with cancer at
MRRH

 Rwanda 2021-07-07 2024-07-07 Social Science and Humanities Degree Award
Roseline Katusiime
ID:
Detecting and analysing micronutrient gaps in dietary patterns in Western Uganda: A comparison of different methods
REFNo: A122ES

1. To compare the 24-hour recall method with direct observation and weighing of food portions, so as to generate knowledge on their accuracy and make expert recommendations by the end of 2021.
2. To use the CIMI to identify nutrient deficiencies in particular gaps of Vitamin A, Zinc and Iron and generate CIMI based recommendations and suggestions on improved diets for the research participants at the end of June 2021.
3. To calculate the costs of improved diets and develop recommendations on affordable nutrient adequate diets for study participants by the end of 2021
4. To assess the advantages and disadvantages of different strategies used by development organizations in western Uganda in encouraging communities to embrace affordable nutrient adequate diets and feeding practices by June 2021

Uganda 2021-07-07 2024-07-07 Agricultural Sciences Degree Award
Deborah  Ojiambo
ID:
Efficacy of Group Activity Adherence Counselling (GAAC) for Adolescents with Unsuppressed HIV viral load at three large HIV clinics in Uganda: Randomized controlled trial
REFNo: SS805ES

1.To examine the barriers such as behavior problems and mental health problems to adherence experienced by adolescents living with HIV.
2.To evaluate the efficacy of GAAC in addressing barriers to adherence among adolescents living with HIV.

3.To assess whether GAAC is associated with viral load suppression, among adolescents living with HIV compared to Standard Service Provision (SSP)
 Uganda 2021-07-07 2024-07-07 Social Science and Humanities Clinical Trial Non-degree Award
Omony Geoffrey
ID:
Safeguarding the war-affected community in Gulu district in Northern Uganda
REFNo: SS830ES

1) To explore and document the impact of research and projects on former child soldiers, both the benefits and the harms, and capture how future projects which focus on the war-affected community can benefit them and what they require for their empowerment
2) to contribute new evidence on the impacts, both direct and indirect, of COVID-19, on persons with disabilities, led by persons with disabilities, with a focus on war-related disabilities in Northern Uganda. This evidence and data will include solutions for disability-inclusive pandemic recovery informed by persons with disabilities
3) to contribute towards the evidence and literature on safeguarding war-affected and post-conflict communities, and create outputs which are accessible to various audiences, including policymakers, academics, journalists, NGOs, and general public
4) to build the esteem of ex-child soldiers, persons with disabilities, and other war-affected groups in Northern Uganda, through involving them in participatory-action research, the design of outputs, and dissemination activities to foster confidence-building, inclusion, and empowerment
Uganda 2021-07-07 2024-07-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
Georgina Pearson
ID:
Living the Everyday: Health-seeking in times of sickness and epidemics at Uganda’s borders
REFNo: SS878ES

1. To document everyday knowledge production on illness, among academics, media, public health practitioners and people living on and across border regions. 2. To identify patterns and practices of health-seeking across the border region., 3. To explore interactions between bodies of knowledge produced by various groups at the border, and detail convergences and divergences., 4. The above objectives will lead on to inform policies in response to potential and emergent threats in border regions.
 UK 2021-07-07 2024-07-07 Social Science and Humanities Non-Clinical Trial Degree Award
Gertrude Kiwanuka
ID:
ETHICAL ISSUES IN RECRUITMENT AND CONDUCTING RESEARCH DURING OUTBREAKS IN RESOURCE LIMITED SETTING
REFNo: SS883ES

1. To determine community voluntariness, understanding and preparedness to participate in research during life threatening infectious disease outbreaks.
2. To explore the perceptions of investigators and policy makers regarding the conduct of research during outbreaks of life threatening diseases in a resource limited setting. Investigators and policy makers play a critical role in setting and driving the research agenda.
3. To examine the ethical issues raised by members of research ethics committees regarding enrollment of participants in research during epidemic situations and the application of alternative designs.
4. To develop a short course on ‘‘Ethical issues in research during epidemics in a resource limited setting”. This will be based on findings from community, investigators and policy maker interactions and extensive review of the literature.

Uganda 2021-07-07 2024-07-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
Annet Khaoya Irene
ID:
Women (in VSLA) Respond
REFNo: SS847ES

The study will be guided by the following key objectives which will also inform the key assessment questions during the survey • To assess how VSLAs (as collectives) and VSLA members are being affected by and coping with the pandemic • To assess the role VSLAs (as collectives) are playing in local response, including not only financial but also social (including health) and political roles • What action and support VSLAs need or want to see from other stakeholders including local and national authorities
Uganda 2021-07-07 2024-07-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
PaweÅ‚ SzymaÅ„ski
ID:
Trade-off between species recognition and individual discrimination in tropical Turtur doves
REFNo: NS256ES

Song is a fundamental signal associated with sexual selection in birds. The processes that allow for species
recognition as well as for individual recognition are inextricably linked and prerequisite for subsequent
decisions about strategy of territory defence and mate choice. The two mentioned functions are somewhat
contradictory, as species recognition needs the uniform feature of a song within a species, whereas
individual recognition is only possible if individuals within a species are somehow acoustically
different. This may lead to conflicting selection pressures that are dependent on the chance of mistaken
species recognition and the importance of individual recognition. The problem that we want to deal with in
this project is the evolutionary compromise between species specific uniformity and individual-specificity of
acoustic signals produced in a sexual selection context. Our model system, the dove species from the Turtur
genus inhabit forest-woodland-savanna habitats in Sub-Saharan Africa. Firstly, we want to describe the
advertisement song variation among and within all Turtur species, in order to identify species and
individually specific song features. Second, we want to experimentally test how birds respond to songs of
the same species and different species in populations occurring allopatrically and sympatrically; and if birds
can discriminate between neighbours and strangers and how similar, co-existing species affect this process.
We plan to use molecular methods to confirm phylogenetic relatedness among the five species and analyse
the genetic structure of same- and different-species populations living in sympatry and allopatry.
 Poland 2021-07-07 2024-07-07 Natural Sciences Non-Clinical Trial Degree Award
JOAN TUSABE
ID: UNCST-2021-R013942
 Understanding knowledge, perceptions and healthcare seeking practices of rural communities in the management of snake bites in Kamuli district.
REFNo: SS912ES

1.To explore and learn from the knowledge, perceptions and preffered health care seeking practices for snake bites among the adult population aged 18-65 years in Kamuli district.

2.To explore knowledge, perceptions and the preferred health care-seeking practices for snake bites among health care workers in Kamuli district

3.To explore the knowledge, perceptions and preferred health care seeking bahaviour among victims of snakebites in Kamuli district.

 Uganda 2021-07-07 2024-07-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
Francis Kalule Kizito
ID:
Molecular identification of benzimidazole resistance associated with beta-tubulin gene in adult Haemonchus contortus worms from goats slaughtered in Kalerwe abattoir in Uganda
REFNo: A133ES

1. To identify common intestinal parasites from goats slaughtered in Kalerwe abattoir in Uganda
2. To determine the prevalence of Haemonchus contortus species identified from goats slaughtered in Kalerwe abattoir in Uganda.
3. To determine the importance of ITS- 2 gene in analyzing genetic diversity among isolates of Haemonchus contortus.
4. To determine the frequency of benzimidazole resistant SNPS F200Y, F167Y and E198A in the partial β-tubulin isotype 1 gene of Haemonchus contortus identified from goats slaughtered in Kalerwe abattoir in Uganda.

 Uganda 2021-07-07 2024-07-07 Agricultural Sciences Non-Clinical Trial Degree Award
Noeline Nakasujja
ID: UNCST-2019-R001428
 ASSESSING THE IMPLEMENTATION OF THE POLICY AND REGULATIONS AGAINST SEXUAL HARASSMENT (PRASH) AT MAKERERE UNIVERSIT
REFNo: SS925ES

1. To assess the extent to which the recommendations from the 2018 committee on SM&H, and the 2018 amendments to PRASH have been implemented.
2. To conduct a dialogue among the University’s key stakeholders focused on addressing SM&H and creating a safe working and learning environment at the Makerere University.
3. To develop a set of recommendations to improve the monitoring and implementation of PRASH

 Uganda 2021-07-07 2024-07-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
Daniel Murokora Murokora
ID: UNCST-2024-R002689
 Transition To Scale: Using the FREO2 Social Enterprise model and technology to scale up access to Oxygen in Uganda
REFNo: HS1238ES

The aim of this project is to evaluate the impact of a reliable oxygen system on improving a) oxygen reliability and affordability, b) clinical outcomes for children.

With a strong emphasis on clinical and technical training, the project activities should:
a) Improve the availability of oxygen, the detection of hypoxaemia, and the access of a sick child to oxygen when they require it
b) Reduce patient and health system costs of oxygen
c) Understand appropriateness, acceptability, and feasibility of the system in the specific context of health facilities in Western Uganda

 Uganda 2021-07-06 2024-07-06 Medical and Health Sciences Non-degree Award
Achilles Katamba
ID: UNCST-2019-R000540
 Evaluation of Xpert® MTB/XDR test for susceptibility testing of Mycobacterium tuberculosis to first and second line drugs
REFNo: HS1395ES

Secondary: To evaluate factors for lab uptake o Training needs o Recording and Reporting Needs o Error rates o Proportion of results interpretable o TAT o Work flow,Assess sensitivity and specificity of Xpert® MTB/XDR test in previously stored sputum samples (previously stored) compared to the WHO-endorsed genotypic (MTBDRplus and MTBDRsl) method as a gold standard.,Assess sensitivity and specificity of Xpert® MTB/XDR test in previously stored sputum samples (previously stored) compared to the WHO-endorsed MGIT960 culture-based drug susceptibility method as a gold standard,The main objective is to independently validate the performance of the Xpert® MTB/XDR test for susceptibility testing of MTB among presumptive XDR-TB patients. The test performance indicators will be compared with current standard drug susceptibility test methods including the MGIT 960 liquid culture drug susceptibility (DST) systems, Line probe Assay and Whole genome sequencing. ,
 Uganda 2021-07-06 2024-07-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Frederick Mubiru Edward
ID:
Market Research on Service Delivery Implications for a 4-month Depot Medroxyprogesterone Acetate Subcutaneous (DMPA-SC) Product
REFNo: HS1520ES

1. To explore stakeholder perceptions of client-centered communication needs for a 4-month DMPA-SC product
2. To explore potential barriers and facilitators to the introduction of a 4-month DMPA-SC product
3. To assess implications for data systems, curriculums, training, supervision, logistics, and quality assurance of introducing a 4-month DMPA-SC product

 Uganda 2021-07-06 2024-07-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eugene Ruzagira
ID: UNCST-2023-R008282
 The impact of COVID-19 on primary health care service provision and utilization in Uganda, Sierra Leone and the Democratic Republic of Congo
REFNo: HS1430ES

I.To determine whether COVID-19 is having an impact on the number of people seen at a selection of healthcare facilities for antenatal care, outpatient visits, routine immunisations, family planning and HIV treatment services, using routine health registration data.
II.To document primary healthcare workers’ experiences in providing care during the outbreak and to identify barriers and facilitators to primary health care provision.
III. To estimate the level of exposure to SARS-CoV-2 among healthcare workers by conducting a repeated serosurvey over a period of 4 months.
IV. To document community members’ experiences in accessing primary healthcare during the outbreak and to identify barriers and facilitators to utilisation.
V. To formulate a set of key findings and recommendations in partnership with stakeholders.

 Uganda 2021-07-06 2024-07-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ronald Moses Galiwango
ID: UNCST-2024-R015239
 SARS-CoV-2 infection and variants surveillance in South-central Uganda (Also known as ‘SARS-CoV-2 surveillance study’)
REFNo: HS1510ES

2.1 Primary objective
To ascertain the burden and transmission patterns of SARS-CoV-2 infection within selected communities in South-central Uganda using rapid antigen tests.
2.2 Secondary objectives
A. To survey for SARS-CoV-2 infection and variants in communities at high-risk of COVID-19 transmission in South-central Uganda through sequencing of specimens positive on both rapid antigen and RT-PCR tests.
B. To determine the acceptability of SARS-CoV-2 antigen rapid diagnostic tests among residents of South-central Uganda.
C. To assess SARS-CoV-2 transmission patterns/dynamics within households and in neighborhoods among communities in South-central Uganda.
D. To assess the burden of prior SARS-CoV-2 infection in South-central Uganda using a validated IgM/IgG antibody test.

Uganda 2021-07-06 2024-07-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
View Sort By:

"A prosperous Science and Technology Led Ugandan Society."

NRIMS