Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Stephen  Cose Christopher
ID: UNCST-2020-R015824
A TB Postmortem Study
REFNo: HS703ES

• To determine the drivers of consent and decline for post mortem procedures and for donation of tissues for medical research
• To undertake postmortem procedures within 8 hours of death
• To determine cell viability and correlate this with time from death
• To undertake flow cytometry and cell stimulation studies to Identify phenotype, function and frequency of TB specific cells within tissues and blood of deceased patients
• To understand the tissue architecture and cell subset organization of cells involved and uninvolved tissues using new imaging techniques.


UK 2020-12-02 2023-12-02 Medical and Health Sciences Non-degree Award
Robert Ssemulende
ID:
Situating the Sangoan techno-complex into Stone Age context at Sango Bay Southern Uganda
REFNo: SS530ES

i. To examine the typological and technological characteristics of the Sangoan lithic
industry
ii. To establish whether the Sangoan techno-complex is situated within the Acheulean,
Middle Stone Age or an independent industry.
iii. To investigate the environmental conditions under which the Sangoan existed.
iv. To establish the chronological sequence of the Sangoan industry from the type site at
Sango Bay
Uganda 2020-12-02 2023-12-02 Social Science and Humanities Degree Award
EVERD  BIKAITWOHA MANIPLE FALUKU
ID:
ASSESSING THE PROPHYLACTIC ACTIVITY, SAFETY AND ECONOMIC IMPACT OF ARTAVOL® AGAINST MALARIA BURDEN AT HOUSEHOLD LEVEL IN APAC DISTRICT, UGANDA
REFNo: HS904ES

General Objective
To evaluate the impact of ARTAVOL on malaria burden at household level in Apac district in Northern Uganda.
Specific Objectives
1.To determine the Prophylactic effect of ARTAVOL against clinical malaria episodes in households.
2.To evaluate the safety profile of ARTAVOL when taken as a prophylactic against malaria.
3.To determine the reduction of malaria parasitemia in the population using ARTAVOL..
4To establish the reduction in malaria treatment cost among household on ARTAVOL beverage
5.To evaluate school attendance among school going children on ARTAVOL at household

Uganda 2020-12-02 2023-12-02 Medical and Health Sciences Non-degree Award
Mary Goretti Nakabugo Goretti
ID: UNCST-2021-R013051
Assessment of Young People’s Literacy and Numeracy Competencies Required in the Workplace and Everyday Life in Uganda
REFNo: SS612ES

i) To provide evidence on young people’s literacy and numeracy competences required in the workplace and everyday life and their relationships with educational attainment and socio-economic characteristics.
ii) To contribute to the range of assessment approaches available in Uganda specifically aimed at informing policy.

Uganda 2020-12-02 2023-12-02 Social Science and Humanities Non-degree Award
Moses Joloba Lutaakome
ID: UNCST-2022-R011558
Accuracy of Novel Diagnostic Tests for Detection of Tuberculosis in Adults: FEND for TB (“FEND-TB Adults”)
REFNo: HS1016ES

Primary Objectives
• To provide clinical specimens and data to FEND for TB researchers and their collaborators in order to determine the diagnostic accuracy and operating characteristics of investigational in vitro tuberculosis diagnostic assays and strategies
• For each participant, to conduct a pre-specified set of standard-of-care diagnostic tests in order to classify that participant’s status with respect to tuberculosis (reference standard).

Secondary:
• To gather parameter estimates for economic analyses

Uganda 2020-12-02 2023-12-02 Medical and Health Sciences Non-degree Award
Waiswa Peter
ID: UNCST-2020-R014921
Optimizing approaches to implementing self-injection of DMPA-SC within the contraceptive method mix: a case of Uganda
REFNo: HS1087ES

AIM: The aim of the study is to optimize approaches to implementing self-injection of DMPA-SC among various contraceptive choices and answer crucial questions about whether SI can enable contraceptive use for women who face barriers and enhance empowerment in Uganda.
4.1 Objectives:
1. Identify who may be the most likely to benefit from the scale-up of DMPA-SC self-injection.
2. Develop effective approaches for supporting the use of DMPA-SC self-injection in a way that helps women overcome barriers and optimize facilitators to contraceptive decision-making and use.
3. Understand the role self-injection can play in promoting empowered contraceptive decision-making and autonomy.
NB: SPECIFIC OBJECTIVES OUTLINED BELOW FORM PHASE ONE OF THE STUDY AND FOCUSES ON OBJECTIVE 1.
4.11 Specific objectives for Phase one:
I. To elucidate the barriers and facilitators to contraceptive decision-making and use among different groups (including identification of groups who face the most barriers), and identification of women with the most interest in SI across study sites of Mayuge and Oyam districts in Uganda.
II. To better understand the context within which DMPA-SC is being rolled out and identify where opportunities lie to conduct research into women’s interest and experience with the method alongside implementation efforts.


Uganda 2020-12-02 2023-12-02 Medical and Health Sciences Non-degree Award
Rhoda Wanyenze
ID: UNCST-2021-R013352
Understand the impact of COVID-19 on the ability of women to access family planning services and products in Uganda
REFNo: HS1031ES

1) To track the utilization of RH/FP and MNCH services including antenatal care (ANC) and postnatal care (PNC)
2) To describe the availability of supplies, commodities and human resources for these services
3) To document innovations and adaptations that the government of Uganda (GOU) and NGOs are implementing to ensure the continuity of services

Uganda 2020-12-01 2023-12-01 Medical and Health Sciences Non-degree Award
Julie Abimanyi-Ochom Abimanyi-Ochom
ID:
IMPACT OF COVID-19 SOCIAL DISTANCING MEASURES ON LIVELIHOODS, HEALTH AND LIFESTYLES STUDY (CIS) IN SUB-SAHARAN AFRICA AND AUSTRALIA
REFNo: SS526ES

The study aims to generate knowledge on the impact of COVID-19 social distancing measures on livelihoods, food security, health, family conflict and lifestyle changes. The study has three main objectives: 1. To describe the extent of application of social distancing measures in select countries. 2. To assess the choice of social distancing measures in select countries and the impact on the different outcome measures – livelihoods, food security, health, family conflict and lifestyle changes. 3. To identify areas most affected by choice of social distancing measures and make recommendations for future recurrent COVID-19 waves or similar pandemics.
Uganda 2020-11-30 2023-11-30 Social Science and Humanities Non-degree Award
Noble Banadda
ID:
FOOD and Local, Agricultural, and Nutritional Diversity
REFNo: A95ES

To develop, implement, and validate innovative, scalable, and sustainable technologies aimed at supporting the nutrition performance of local food systems in Africa, while strengthening agro-biodiversity and food diversity as well as diversity of healthy diets
Uganda 2020-11-30 2023-11-30 Agricultural Sciences Non-degree Award
CHARLES BENSTONS IBINGIRA RUKAMBURA
ID: UNCST-2021-R008521
Determination and characterisation of viral load and antibody profiles in samples from multiple sites of COVID-19 patients in Uganda
REFNo: HS1035ES

4 Study Objectives
This study will aim to determine viral load and antibody production / levels in diverse samples from COVID-19 patients.
Specific aims:
1. Determine and compare virus levels in blood, saliva, naso/oro-pharyngeal swabs, urine, and stool of COVID-19 patients.
2. Determine and compare antibody levels (IgM, IgG & IgA) in blood, saliva, naso/oro-pharyngeal swabs, urine, and stool of COVID-19 patients.
3. Determine and assess neutralising antibody (IgG & IgA) activity (in plasma, naso-phargygeal, saliva samples respectively) from COVID-19 patients.

Uganda 2020-11-30 2023-11-30 Medical and Health Sciences Non-degree Award
Atukunda  Gilbert
ID: UNCST-2020-R014643
Analysis of Workplace Practices of Educational Leadership and Management Graduates of Aga Khan University-IED, EA in Uganda.
REFNo: SS559ES

The objective of the study is to examine how Educational Leadership and Management graduates of Aga Khan University-IED, EA have transformed their workplace practices using the knowledge and skills obtained from the course.
Uganda 2020-11-27 2023-11-27 Social Science and Humanities Degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
An Evaluation of the Pediatric Discharge Process following Hospital Admission with Sepsis/Severe Infection in Uganda
REFNo: HS928ES

The primary objective of this study is to evaluate the typical pediatric discharge process at a representative sample of hospitals in Uganda. The study will be guided by the following specific objectives.
Specially we intend to:
1. To assess the readiness of health facilities in providing minimum standard discharge care.
2. To assess health workers practices in the discharge care processes
3. To determine health worker perceptions of the quality of discharge processes.
4. To explore patient caregiver perceptions of the quality of discharge care experienced while their child was treated at the health facility.

Uganda 2020-11-27 2023-11-27 Medical and Health Sciences Non-degree Award
Anthony  Batte
ID: UNCST-2022-R011127
Prevalence of hypertension, HIV and Hepatitis B among participants of the world kidney day 2020 health screening in western Uganda (HHH Study)
REFNo: HS978ES

1. To describe the prevalence of hypertension, HIV and hepatitis B among participants of the world kidney day 2020 health screening in western Uganda
2. To evaluate the predictors of hypertension, HIV and hepatitis B among participants of the world kidney day 2020 health screening in western Uganda

Uganda 2020-11-27 2023-11-27 Medical and Health Sciences Non-degree Award
Emmanuel Kaggwa Henry
ID:
PEDAGOGICAL LEADERSHIP APPROACHES, LEARNING ENVIRONMENT AND ACADEMIC PERFORMANCE OF STUDENTS IN SECONDARY SCHOOLS: A CASE STUDY OF NAKASEKE DISTRICT-UGANDA
REFNo: SS627ES

1. To assess the state of academic performance of students in the secondary schools of Nakaseke district.
2. To establish the correlation between pedagogical leadership approaches and academic performance of students in Nakaseke district.

3. To examine the influence of learning environment on academic performance of students in Nakaseke district.

4. To establish a new, effective and practical pedagogical leadership approach that will enhance academic performance of students in Nakaseke district.
Uganda 2020-11-27 2023-11-27 Social Science and Humanities Degree Award
William Buwembo
ID:
Anti-COVID-19 immunoglobulins G and M in blood specimens collected before lockdown at two urban clinics of Kampala, Uganda
REFNo: HS995ES

1. To determine the COVID-19 specific sero-prevalence at two urban clinics of Kampala, Uganda.
2. To determine the quality of virus specific antibody IgG in seropositive specimens
Uganda 2020-11-27 2023-11-27 Medical and Health Sciences Non-degree Award
Peter Olupot-Olupot Olupot
ID: UNCST-2020-R014798
Feasibility and Effectiveness of the National Research Information Management Systems (NRIMS) in Uganda; a Nested study within the Scaling up of capacity of Research Ethics Committees in Uganda (SCRECU).
REFNo: HS1052ES

Main Objective. To assess the feasibility and effectiveness of the National Research Information Management System (NRIMS) for effective Research Ethics Committee (REC) review process, facilitate multiple REC review, national registration and subsequent monitoring of approvals in Uganda. Specific. To assess the feasibility and effectiveness of NRIMS for review, registration and monitoring of research in Uganda. 2. To evaluate the cost economics of implementation of NRIMS.
Uganda 2020-11-27 2023-11-27 Medical and Health Sciences Non-degree Award
Joseph Ochieng
ID:
Ethical and social issues for COVID-19 vaccine access in Uganda
REFNo: HS1101ES

The goal of the proposed study is to assess stakeholders’ awareness of ethical and social issues as well as perceptions of priority setting for COVID-19 vaccine accessto stimulate debate in preparation for COVID-19 vaccine and development of a model approach to priority setting in a Ugandan setting.

Aim 1. Assess stakeholders’ awareness of ethical considerations and social issues associated with COVID-19 vaccine access in Uganda
Aim 2. Assess stakeholders’ perceptions on ethical and social issues associated with priority setting for COVID-19 vaccine access in Uganda
Aim 3. Evaluate existing policies and guidelines on priority setting for COVID-19 vaccine access in Uganda
Aim 4. Develop a model approach to priority setting for COVID-19 vaccine access in Uganda

Uganda 2020-11-27 2023-11-27 Medical and Health Sciences Non-degree Award
Grace Brown
ID:
Sustainable Coffee Farming: Agricultural Growth, Cultural Shift, and Its Direct Effect on Decreased Gorilla/Human Disease Transmission
REFNo: NS87ES

To record the influence of local agricultural shifts on the health of gorilla group populations within Bwindi.
-Record diseases and illnesses through fecal sample that are linked to some sort of human interaction, whether it be direct or through livestock.
-Determine how coffee farmers perspectives on gorilla conservation have changed, if at all, with their participation in Gorilla Conservation Coffee.
-Study how farmers with steadier incomes can better support sustainability and conservation efforts within Bwindi Impenetrable National Forest.

USA 2020-11-26 2023-11-26 Natural Sciences Non-degree Award
Claire Akwongo Julie
ID:
Prevalence, Risk factors of exposure and Socio-Economic impact of Peste des Petits Ruminants (PPR) in Karenga District, Karamoja Region, Uganda
REFNo: A71ES

1. Determine the sero-prevalence of anti-SRM in goats and sheep in Karenga District using the Competitive Enzyme-linked Immunosorbent assay. 2. Determine the socio-economic impact of PPR amongst communities in Karenga using participatory epidemiology. 3. Establish the risk factors associated with the occurrence and spread of PPR in Karenga District using participatory epidemiology.
Uganda 2020-11-26 2023-11-26 Agricultural Sciences Degree Award
Chris Opesen C
ID:
EXPLORING THE PHILANTHROPY PRACTICE IN UGANDA
REFNo: SS471ES

The overall objective of this study is to explore the landscape for and of philanthropy in Uganda. The study has the following specific objectives:

I.To conduct a legal and policy analysis for philanthropy in Uganda including tax laws. Expected outputs
II.To identify local philanthropic initiatives in the five (5) districts of Kampala, Mbarara, Gulu, Arua and Masaka.
III.To establish the factors that enhance and hinder local philanthropy.
IV.Lastly, to develop recommendations for strengthening philanthropic practice in Uganda, as well as emerging research areas.

Uganda 2020-11-26 2023-11-26 Social Science and Humanities Non-degree Award
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