Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Jane  Namusisi
ID: UNCST-2021-R013619
seizure control and associated factors among children with epilepsy at Mbarara Regional Referral Hospital
REFNo: HS1657ES

MAIN OBJECTIVE
To determine the seizure control status and describe its associated factors among children attending the Epilepsy Clinic at MRRH for at least six months.
SPECIFIC OBJECTIVES;
1. To identify the seizure types among children under care for at least six months at the Epilepsy Clinic, MRRH.
2.To determine the proportion of children with epilepsy with poor seizure control under care for at least six months at the MRRH Epilepsy clinic.
3.To identify the factors associated with poor seizure control among children under care for at least six months at the MRRH Epilepsy clinic.

Uganda 2021-09-17 2024-09-17 Medical and Health Sciences Non-Clinical Trial Degree Award
Achilles Katamba
ID: UNCST-2019-R000540
Human-Centred Design and Communities of Practice to Improve Delivery of Home based Tuberculosis Contact Investigation in Uganda
REFNo: HS1720ES

General Objective: The study aims to assess the effectiveness of an enhanced intervention strategy for implementing TB contact investigation relative to usual care. Specific Objectives: 1.To compare the implementation, effectiveness, and public health impact of TB contact investigation delivered via an enhanced intervention strategy vs. the usual care strategy in a stepped-wedge, cluster-randomized implementation trial. 2.To identify implementation processes and contextual factors that influence the effectiveness of the intervention strategy for TB contact investigation. 3.To compare the costs and epidemiological impact of the intervention and usual care strategies for TB contact investigation.
Uganda 2021-09-17 2024-09-17 Medical and Health Sciences Clinical Trial Non-degree Award
Susan  Nabadda
ID: UNCST-2020-R014331
SeqCOVID consortium: EAC participation – Sequencing of COVID-19 isolates from the East African Region
REFNo: HS1592ES

Epidemiological Analysis of current COVID outbreak,Capacity Building in East Africa and setting up of Prospective COVID Surveillance Platform,Diagnostic and Vaccine Development for East African COVID variants: - describe East African COVID variants and predict immunogenic epitopes and drug targets in silico, The aim of the present project is for the East African region to actively contribute data for COVID-19 drug and vaccine development, to equip the region for the time after a vaccine and drugs were developed and also to prepare for future outbreaks.,
Uganda 2021-09-16 2024-09-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Grace Nalumu
ID:
ASSESSING FACTORS ASSOCIATED WITH NEONATAL DEATHS IN BUSIA DISTRICT; CASE STUDY OF MASAFU, DABANI AND BUSIA HEALTH FACILITIES
REFNo: HS1711ES

1. To assess factors associated with neonatal deaths in Busia district such that we make recommendations, according to the findings, on what measures to adopted in order to reduce neonatal mortality in the district and the country,4. To examine health facility factors associated with neonatal deaths in Busia district,3. To establish neonatal related factors associated neonatal deaths in Busia district ,2. To determine maternal factors associated with neonatal deaths in Busia district ,
Uganda 2021-09-16 2024-09-16 Medical and Health Sciences Non-Clinical Trial Degree Award
Janet SEELEY
ID:
Multimorbidity in Africa - Increasing Understanding of the Health Workers’ Experiences and Epidemiology (MAfricaEE)
REFNo: SS998ES

Explore the healthcare professionals' (HCPs) experiences of treating and managing patients with multi-morbidity in Uganda and what health workers see as the main barriers to optimal care provision. How do health care professiönals view the potential impacts of COVID-19 on care for patients with multi-morbidity?
UK 2021-09-13 2024-09-13 Social Science and Humanities Non-Clinical Trial Non-degree Award
Frederick  Oporia
ID:
Improving use of seaworthy life jackets among boaters on Lake Albert, Uganda. A cluster randomized trial
REFNo: SS992ES

1. To estimate the prevalence of life jacket use among boaters on Lake Albert.

2. To identify the determinants of life jacket use among boaters on Lake Albert

3. To determine the seaworthiness of life jackets used by boaters on Lake Albert

4. To design a behavior change intervention aimed at improving use of seaworthy life jackets among boaters on Lake Albert

5. To pilot and evaluate the effectiveness of a behavior change intervention on improving use of seaworthy life jackets among boaters on Lake Albert

Uganda 2021-09-10 2024-09-10 Social Science and Humanities Degree Award
Carolyn Pelnik
ID:
Identifying and Easing Constraints on Microenterprise Location within Kampala, Uganda
REFNo: SS935ES

This project asks whether business relocation within the city could increase profits for microfirms in Kampala, Uganda, and if so, then what frictions (constraints) restrict a firm’s ability to relocate without intervention. Ultimately, this project plans to use a multi-arm randomized experiment to accomplish 3 aims: to detect appetite for business relocation, whether relocation increases profits, and which of the tested frictions might constrain location choice. In the first phase of the research, the project will survey microfirms in Kampala to understand their current locations, how profits vary by location across the city, what aspirations the business owners have with respect to future business growth, and what challenges they perceive to accomplishing business growth.
USA 2021-09-10 2024-09-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Paineto Masengere
ID: UNCST-2021-R013195
Perceptions, barriers, and facilitators of adoption of healthy lifestyles for cardiovascular disease prevention among slum communities in Kampala, Uganda
REFNo: HS1661ES

1. To explore how slum dwellers in Kampala district define a healthy lifestyle in the context of cardiovascular disease prevention.
2. To explore the barriers and facilitators to adopting recommended lifestyles for cardiovascular disease prevention among slum dwellers.
3. To explore the potential roles of community actors in slums in cardiovascular disease prevention.

Uganda 2021-09-10 2024-09-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Felix Oyania
ID: UNCST-2021-R013492
Feasibility of Primary Repair for Anorectal Malformations in Uganda
REFNo: HS1632ES

To determine the feasibility of primary repair for anorectal malformations in Uganda.,
Uganda 2021-09-10 2024-09-10 Medical and Health Sciences Non-Clinical Trial Degree Award
FRANK MULINDWA
ID:
Changes in insulin kinetics after withholding dolutegravir in Ugandan HIV patients who develop diabetes while on dolutegravir.
REFNo: HS1493ES

To determine changes in; insulin secretion, insulin sensitivity, insulin clearance and HBA1C at 24 weeks after DTG discontinuation in Ugandan HIV patients who develop diabetes while on DTG.
Uganda 2021-09-09 2024-09-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Martha Musyoka Mbenia
ID:
PREDICTORS OF ADVERSE FETO-MATERNAL OUTCOMES AMONG MOTHERS ADMITTED WITH ANTEPARTUM HEMORRHAGE AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS1450ES

To describe adverse outcomes and determine predictors of adverse feto-maternal outcomes in mothers with antepartum hemorrhage at Mbarara Regional Referral Hospital
Kenya 2021-09-09 2024-09-09 Medical and Health Sciences Clinical Trial Degree Award
Jimmyy Opee
ID:
PROPORTION AND FACTORS ASSOCIATED WITH INTRA-PROCEDURAL PAIN AMONG WOMEN UNDERGOING MANUAL VACUUM ASPIRATION FOR INCOMPLETE ABORTION AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS1462ES

General objective
To determine the proportion and factors associated with intra-procedural pain among women undergoing Manual Vacuum Aspiration for incomplete abortion at gynecology ward at Mbarara Regional Referral Hospital.

Specific objectives
1. To determine the proportion of women with intra-procedural pain undergoing Manual Vacuum Aspiration for incomplete abortion at gynecology ward at Mbarara Regional Referral Hospital.
2. To determine the factors associated with intra-procedural pain among women undergoing Manual Vacuum Aspiration for incomplete abortion at gynecology ward at Mbarara Regional Referral Hospital.

Uganda 2021-09-09 2024-09-09 Medical and Health Sciences Non-Clinical Trial Degree Award
Ronald Mulebeke
ID:
A pilot study to assess the impact of Supportive Supervision and Behavior Change Communication at private health facilities in Uganda
REFNo: HS1588ES

This study will assess the impact of supportive supervision and behaviour change communication to improve the quality of malaria care and data management delivered by clinicians at private health facilities in Uganda.
Uganda 2021-09-09 2024-09-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ANTHONY KAYIIRA
ID: UNCST-2020-R014108
Understanding Reproductive Health among Survivors of Paediatric and Young adults (URHSPY) Cancers: a mixed method study
REFNo: HS1652ES

To explore the knowledge, perceptions, and attitude of; parents or caretakers of children with cancer, and health workers on cancer treatment-related reproductive morbidity, at the Uganda Cancer Institute,To describe self-reported reproductive morbidity associated with cancer treatment among childhood and young-adult cancer survivors.,To establish the extent of reproductive morbidity associated with cancer treatment among young cancer survivors in Uganda. In addition, we aim to explore the contextual enablers and barriers to addressing cancer treatment-related reproductive morbidity in Uganda.,
Uganda 2021-09-09 2024-09-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan  Nabadda
ID: UNCST-2020-R014331
Study Protocol for the Evaluation of Covid 19 Antibody and Antigen Rapid Diagnostic Test (RDT) In the EAC Partner States
REFNo: HS1591ES

Evaluation of ELISA cross-reactivity on stored archived negative samples between East African Partner States. ,Evaluation RDT performance differences between the East African Partner States,- Evaluate the clinical specificity of antibody RDT and ELISA using serum/plasma specimens from COVID-19 negative specimens from pre-COVID-19 (archived stored samples),- Evaluation of COVID19 antibody RDTs and ELISA’s in the East African region, using serum/plasma samples from COVID-19 confirmed based on RT-PCR results (RT-PCR positive test results). ,Evaluation of COVID19 antigen RDTs against gold standard PCR in the East African region,
Uganda 2021-09-09 2024-09-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan  Nabadda
ID: UNCST-2020-R014331
Evaluation of TUBEX Typhoid TF IgM Antibody test for Early Diagnosis of Typhoid fever Among patients in Uganda
REFNo: HS1548ES

1) To carry out blood culture testing on all samples from patients with signs and symptoms of typhoid fever in the selected facilities of Uganda.
2) To carry out serological testing for Salmonella antibodies using the TUBEX Typhoid TF IgM Antibody test on the serum samples of consented/assented patients whose samples grew Salmonella Typhi.

Uganda 2021-09-09 2024-09-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Fred Nalugoda
ID: UNCST-2021-R013343
Exploring the impact of out-migration on remaining partners’ HIV and sexual behavior perceptions and practices in Rakai, Uganda: a qualitative study.
REFNo: SS981ES

The overall aim of this study is to qualitatively explore the impact of out-migration amongst heterosexual couples on non-migrating partners’ HIV and sexual behavior perceptions and practices in Rakai, Uganda.
Uganda 2021-09-09 2024-09-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jafesi Pulle
ID: UNCST-2020-R014213
TRUST IN MEDICAL RESEARCH AMONG PATIENTS AT A REGIONAL REFERRAL HOSPITAL AND COMMUNITY MEMBERS IN LIRA DISTRICT, NORTHERN UGANDA
REFNo: HS1685ES

Explore community perceptions of trust in medical research,2. Determine the other factors associated with trust of medical research,1. Compare level of trust for medical research among community members and persons that are hospitalized.,To compare the level of trust in medical research among people hospitalized at a hospital and the community members, identify associated factors and explore prevailing community perceptions of trust in medical research.,
Uganda 2021-09-09 2024-09-09 Medical and Health Sciences Non-Clinical Trial Degree Award
Daniel Mongovin David Thomas
ID:
Dry Rifting in the Albertine-Rhino Graben (DRIAR)
REFNo: NS160ES

To conduct a geological investigation of faulting associated with continental rifting in the magma-poor rift environment in the northernmost Western Branch of the East African Rift System.
USA 2021-09-08 2024-09-08 Natural Sciences Non-Clinical Trial Degree Award
Julian Bagyendera Kobutungi
ID:
Gender, Youth and Social Inclusion Baseline Assessment for the USAID Local Partner Health Services – Ankole (USAID LPS – Ankole)
REFNo: SS1002ES

The main objective is to conduct a mixed method gender and youth social inclusion assessment which includes a literature review; collection of primary quantitative and qualitative data.,
Uganda 2021-09-08 2024-09-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
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