Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
ANTHONY NUWA
ID: UNCST-2022-R011102
Host Immune dynamics following seasonal malaria chemoprevention in African children
REFNo: HS4350ES

Main Objective
1. To understand the dynamics of host immunity in settings implementing seasonal malaria chemoprevention.
Specific Objectives
1. To comprehensively profile antibody immune responses in individuals before and after single and multiple rounds of SMC.
2. To comprehensively profile the innate and adaptive cellular immune response in individuals living in an area with sustained SMC.
Uganda 2024-06-05 17:10:29 2027-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Olive  Kabaguma
ID: UNCST-2023-R005849
PSYCHOSOCIAL FACTORS AND WELLNESS OF MIDLIFE RELIGIOUS SISTERS IN UGANDA
REFNo: SS2503ES

To establish the association between psychosocial factors and wellness among religious sisters in Uganda.,
Uganda 2024-06-05 17:03:18 2027-06-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Rachel McMullan
ID:
Tackling Antimicrobial Resistance Through Professional Learning: Open Societal Challenge
REFNo: SS2650ES

Aim: To synthesise knowledge around the work practices and behaviours required for effective antimicrobial stewardship and identify which of these could be strengthened by professional learning programmes and training. Objectives: 1. To describe health professionals’ practices and behaviours around antibiotics and related tools, processes, networks and challenges 2. To understand the impacts of AMS-related change on health professionals’ practices and behaviours in the work place 3. To identify how health professionals engage with learning opportunities for AMS/AMR, and associated knowledge gaps 4. To identify the AMS-related behaviour(s) in need of change that could be supported in a future intervention 5. To assess current antimicrobial prescribing practices in healthcare facilities across Eastern Uganda.
UK 2024-06-04 7:28:02 2027-06-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
Godfrey  Siu
ID: UNCST-2021-R005439
Adaptation and Piloting of the Parenting for Respectability Programme for Hybrid Disability Inclusive Parenting Study; Feasibility, Process, and Lessons from Uganda
REFNo: HS4054ES

Research objective
The study aims to adapt and test the feasibility and acceptability of the PfR programme for parents with disabilities and parents of children with disabilities.

Specific objectives
i.To assess the extent to which existing national policies respond to the needs of parents and children with disabilities
ii.Qualitatively assess knowledge, attitudes and practices on parenting among parents and children with disabilities
iii.To adapt and pilot the existing Parenting for Respectability programme manual for facilitator-assisted WhatsApp group-based delivery in order to assess accessibility, functionality, inclusivity, and examine facilitating and hindering factors around disability inclusive parenting

Uganda 2024-05-31 18:34:28 2027-05-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sarah Zalwango Karen
ID: UNCST-2021-R005660
Title:Evaluating the Burden of Post-Tuberculosis Morbidity Among TB Disease Survivors in Uganda: A Pilot Feasibility Study
REFNo: HS4037ES

The objective of the proposal is to conduct a pilot feasibility study on post-tuberculosis (TB) survivors as a preliminary step in planning for a future large cohort study to broadly evaluate post-TB morbidity. ,
Uganda 2024-05-31 18:33:32 2027-05-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Phiona Arineitwe
ID:
Institutional Support and Teacher Competence Mediated by Organisational Learning in Government-Aided Secondary Schools in South Western Uganda, Uganda.
REFNo: SS2518ES

1. To investigate the influence of institutional support on teacher competence in government-aided secondary schools in South Western Uganda.
2. To establish the influence of institutional support on organisational learning in government-aided secondary schools in South Western Uganda.
3. To determine the influence of organisational learning on teacher competence in government-aided secondary schools in South Western Uganda.
4. To test the mediating effect of organisational learning on the influence of institutional support on teacher competence in government-aided secondary schools in South Western Uganda

Uganda 2024-05-31 18:31:51 2027-05-31 Social Science and Humanities Non-Clinical Trial Degree Award
Herbert Kiwalya
ID: UNCST-2024-R004872
Electronic healthcare registries: An evaluation of current practices, stakeholder perceptions and implementation effectiveness.
REFNo: HS4359ES

Evaluate the effectiveness and usability of an electronic registry implemented to enhance the availability and accessibility of patient-level data for quality improvement and decision-making.,Describe the implementation requirements for an electronic healthcare registry in Uganda and identify barriers that may be encountered during its’ setup and utilisation.,Assess the current practices and challenges in documenting, accessing and using patient-level, registry-based healthcare data in eastern Uganda.,Describe stakeholder perceptions of electronic healthcare registries to facilitate quality improvement, clinical benchmarking and research at local, regional, national and international levels of the healthcare system in Uganda, Ethiopia, and South Africa.,We aim to understand current views of stakeholders in three African countries about the use of electronic healthcare registries. This will include developing a detailed understanding of the local context from eastern Uganda. Following implementation of an integrated electronic registry to support quality improvement work we will conduct a process evaluation that will allow us to reflect on the effectiveness of our registry in this setting.,
Uganda 2024-05-31 18:30:37 2027-05-31 Medical and Health Sciences Non-Clinical Trial Degree Award
Alice Endra Ezuru
ID:
Access and Application of digital technologies among fishing communities in Uganda: a case of Lake Victoria community
REFNo: SS2677ES

i). To examine the information needs (personal, trade, health, fishing inputs, technology) of the fishing communities of Lake Victoria, Uganda.
ii). To establish the digital technologies used in information access by the fishing communities of Lake Victoria, Uganda.
iii). To determine the access and application of digital technologies in information dissemination within the fishing communities and managers of Lake Victoria in Uganda.
v). To examine challenges (if any) in access and application of digital technologies among the fishing communities of Lake Victoria in Uganda.

Uganda 2024-05-31 18:29:42 2027-05-31 Social Science and Humanities Non-Clinical Trial Degree Award
Ali Kudamba
ID:
Anticancer activity and safety of Rhoicissus tridentata (L.f) Wild & R.B. Drumm. as used in the treatment of prostate cancer in the Elgon sub-region, Uganda
REFNo: HS3007ES

To determine the effect of aqueous, methanol, & total crude of Rhoicissus tridentata (Lf.) Wild & R.B. Drumm. on the antiproliferative activity (% growth inhibition or cell viability) of the prostate cancer cell line,To assess the effect of aqueous, methanol, and total crude extracts from Rhoicissus tridentata (Lf.) Wild & R.B. Drumm. on the apoptotic index of the prostate cancer cell line. ,To assess the effect of methanol, aqueous, and total crude extracts Rhoicissus tridentata (Lf.) Wild & R.B. Drumm. on sub-acute toxicity in Wistar albino rats. ,To assess the effect of methanol, aqueous, and total crude extracts Rhoicissus tridentata (Lf.) Wild & R.B. Drumm. on acute toxicity in female Wistar albino mice. ,To determine the phytochemical compositions of aqueous and methanol extracts of Rhoicissus tridentata (Lf.) Wild & R.B. Drumm. harvested from the volcanic soils of mountain Elgon slopes.,To describe the medicinal plants used in the treatment of cancers with emphasis on prostate cancer,The study is aimed at assessing the anticancer activity and safety of Rhoicissus tridentata (L.f.) Wild & R.B. Drumm used in the treatment of prostate cancer in the Elgon sub-region. ,
Uganda 2024-05-31 18:28:36 2027-05-31 Medical and Health Sciences Non-Clinical Trial Degree Award
Lauren Wolf
ID:
The Spatial Ecology of the Red Colobus Monkeys
REFNo: NS808ES

The overall goal of this project is to comprehensively understand the ecological and social determinants that influence the spatial behavior of the Ashy Red Colobus Monkey.
USA 2024-05-31 18:27:17 2027-05-31 Natural Sciences Non-Clinical Trial Degree Award
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