Pauline Byakika-Kibwika
ID: UNCST-2019-R001206
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Investigation of mpox transmission, disease sequel, and molecular epidemiology in Uganda (Mpoxep)
REFNo: HS5387ES
Primary Objectives
1. To characterize the socio-demographic, clinical, immunological, and virologic epidemiology of Mpox cases in Uganda.
2. To describe the natural history and asymptomatic transmission dynamics of Mpox among contacts.
3. To assess risk factors for clinical hospitalization, ICU admission, and fatal Mpox outcomes.
4. To investigate long-term sequelae among Mpox survivors.
Secondary Objectives
1. To determine the incidence and prevalence of Mpox among high-risk populations (long-distance truck drivers, commercial sex workers, refugees, and PLHA).
2. To assess infection risk and asymptomatic transmission using serology among contacts.
3. To identify risk factors for infection among ‘de novo’ cases with no documented epidemiological link.
4. To explore socio-anthropological factors influencing Mpox transmission, prevention, and care-seeking behavior.
5. To identify potential animal reservoirs of MPXV in Uganda.
6. To describe histopathologic features of Mpox skin lesions and localization of MPXV in different body organs and tissues.
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Uganda |
2024-12-23 10:56:56 |
2027-12-23 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Wycliff Odude
ID: UNCST-2024-R002431
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Small-scale field evaluation of the efficacy, residual activity and acceptability of Sovrenta® 15WP against Malaria Vectors in Adjumani district, West Nile, Uganda.
REFNo: HS5300ES
1. To determine the susceptibility levels of both wild-type and Kisumu strain malaria vectors to Sovrenta® 15WP insecticide in Adjumani District, West Nile, Uganda.
2. To determine the comparative residual activity of Sovrenta® 15WP and Actellic 300CS insecticides on common wall-type surfaces in Adjumani, West Nile, Uganda over 10 months.
3. To generate specific information related to the acceptability of Sovrenta® 15WP insecticide as a new product by the community in Adjumani, West Nile, Uganda.
4. To assess the ease of use of the Sovrenta by the spray operators under field conditions in Adjumani District, West Nile, Uganda.
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Uganda |
2024-12-10 16:05:33 |
2027-12-10 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Roy Mayega William
ID: UNCST-2022-R010983
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Africa Regional Education System Resilience Observatory (ARESRO) Study - A Case Study of Uganda
REFNo: SS3453ES
General objective
To contribute to the improvement of the education system resilience in Uganda through evidence-informed programming.
Specific objectives
1) To explore the meanings and practices of education system resilience in Uganda
2) To explore the potential impact of future shocks and stressors, risk, vulnerability, and capacities (absorptive, adaptive, and transformative) on the future education ecosystems and outcomes in Uganda
3) To identify effective approaches and planning to address the future shocks and stressors, risks, vulnerabilities, and capacity for better education system resilience in Uganda
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Uganda |
2024-12-10 16:04:12 |
2027-12-10 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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ALEX ARIO RIOLEXUS
ID: UNCST-2024-R002455
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DEATHS AND INFECTIONS AVERTED, A COST - EFFECTIVENESS ANALYSIS AND FACTORS THAT INFLUENCE ADOPTION AND IMPLEMENTATION OF THE 7-1-7 TARGETS IN UGANDA: A case study of three Priority diseases
REFNo: HS5278ES
1.To estimate the number of deaths and cases from prioritized diseases (EVD, anthrax, Measles and Rift Valley fever disease) averted if 7-1-7 targets are met in Uganda
2.To conduct a cost-effectiveness analysis for Uganda’s Ministry of Health implementing the 7-1-7 framework in responding to prioritized diseases (EVD, anthrax, Measles and Rift Valley fever disease) using societal perspective.
3.To explore and profile the factors that influence the adoption and implementation of 7-1-7 targets among different stakeholders in Uganda
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Uganda |
2024-12-10 16:02:45 |
2027-12-10 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Violet Nkwanzi
ID: UNCST-2024-R002493
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Examining the Impact of Adverse Childhood Experiences on Human Trafficking Vulnerability and the Long-term Mental Health Outcomes of Women Survivors of Trafficking (18-35 years) in Uganda.
REFNo: SS3451ES
Aim 1: To quantitatively examine the association between ACEs, human trafficking vulnerability, and long-term mental health outcomes (anxiety, depression, PTSD).
Aim 2: To determine the factors that moderate the effects of ACEs on human trafficking vulnerability and the long-term mental health outcomes of women survivors of trafficking.
Aim 3: To qualitatively explore sources of resilience and gaps in existing policies and services for women affected by human trafficking in Uganda
To inform comprehensive survivor centered interventions, this study will collect additional data on quality of life, gender-based violence, substance use and financial capability of survivors of trafficking.
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Uganda |
2024-12-10 16:01:57 |
2027-12-10 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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Akusa Patrice Mawa
ID: UNCST-2024-R015660
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Service availability and readiness assessment for establishing biobanks of patient left-over samples from routine healthcare provision in Uganda and Kenya
REFNo: HS5328ES
1. To assess the current practices with left-over samples in hospitals and the attitude, willingness, and acceptability of stakeholders towards biobanking.
2. To audit human resources, laboratory infrastructure, governance, and data systems to understand available resources to support the establishment of left-over sample biobanks in health facilities
3. Undertake a detailed analysis of costs that will be needed to sustain operational activities on a yearly basis for either a federated or centralised approach of biobanking left-over samples in Uganda and Kenya
4. Assess the regulatory environment and engage relevant national regulatory bodies to adapt guidelines for left-over sample biobanking in Uganda and Kenya.
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Uganda |
2024-12-10 16:00:04 |
2027-12-10 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Stephen Tukwasibwe
ID: UNCST-2022-R011535
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Surveillance of P. falciparum Drug and Diagnostic Resistance in Refugee Populations
REFNo: HS5230ES
To conduct comprehensive malaria molecular surveillance in refugee populations to generate high quality molecular, epidemiological and entomologic data for monitoring geographic and temporal trends and thereby inform interventions to best protect refugee and local host populations.
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Uganda |
2024-12-10 15:59:04 |
2027-12-10 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Jude Nicholars Iyke
ID: UNCST-2023-R007962
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THE EFFECTS OF PERSONALITY TRAITS ON THE ACCEPTANCE OF BIOMETRIC CONTROLLED HEALTH INFORMATICS IN PUBLIC HOSPITALS IN UGANDA
REFNo: SIR430ES
The purpose of this sequential mixed-method design study is to assess the relationship between the personality traits and acceptance of Biometric Controlled Health Informatics in Gulu and Soroti Regional Referal public Hospitals in Uganda that will help health strategists and policy makers evaluate how the personality traits of health workers affect their acceptance of biometric controlled health informatics (BCHI) for secure access for clinical and non-clinical health workers to patient records in public hospitals in Uganda . ,To examine how personality traits affect the acceptance of Biometric Controlled Health Informatics in these public hospitals using the acceptance model that was developed for that purpose,To determine the connection between acceptances of Biometric Controlled Health Informatics and personality traits in these public hospitals.,To establish health workers’ awareness of Biometric Controlled Health Informatics in these public hospitals,
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Nigeria |
2024-12-10 15:54:44 |
2027-12-10 |
Engineering and Technology |
Non-Clinical Trial |
Degree Award |
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Susan Nayiga
ID: UNCST-2020-R014642
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Managing AMR: Everyday experience with antibacterial drug resistant infections in central Uganda
REFNo: SS3469ES
1. To track the trajectories of illness, care, recovery or decline of patients diagnosed with antibacterial drug resistant infections.
2. To link the social, economic and illness histories and opportunities of patients with their onward trajectories with antibacterial drug resistant infections
3. To identify equity dimensions of the how systems manage antibacterial drug resistant infections and points for intervention to support recovery
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Uganda |
2024-12-10 15:53:27 |
2027-12-10 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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Francis Kakooza
ID: UNCST-2024-R002803
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Evaluation of capture enrichment for viral sequencing in a remote setting in Uganda.
REFNo: HS5270ES
Objective 2: Evaluate Analytical Performance in Uganda. NGS testing of blood samples from confirmed clinical cases and suspected clinical samples will be conducted. This includes de-identified archived blood samples collected from a sepsis cohort among participants who consented for their samples to be used for future research related to sepsis in Fort Portal, Uganda, at Fort Portal Regional Referral Hospital, which has enhanced biosafety capabilities. ,Objective 1: Develop and Optimize NGS Platform To pilot the use of a field-deployed portable next-generation sequencing for testing of archived sepsis blood samples in Uganda to search for hantavirus or bunyavirus infections. The project plans to field test the Oxford Nanopore Technologies (ONT) platform with archived blood samples. Phylogenetic trees will be developed, and virus clades and variants or new viruses will be described. The performance of enriched-NGS to detect the virus will be compared to index testing with RT-PCR when there are 5 or more positive results.,
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Uganda |
2024-12-10 15:52:01 |
2027-12-10 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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