Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Kirabo Suubi
ID: UNCST-2023-R005659
 Pre-post intervention study to assess the implementation of SAFE program as well as its effectiveness in improving the prevention of, and response to child sexual abuse and exploitation in Western Uganda.
REFNo: SS2506ES

The goal of this evaluation is to assess the process and effectiveness of the SAFE intervention in improving the prevention and response to child sexual abuse and exploitation in Western Uganda. The following are the specific objectives of the study. Baseline 1. Assess pre--intervention knowledge, perceptions, attitudes, agency, and intentions/behaviors related to mitigating risk exposure to child sexual abuse and exploitation: including reporting and help-seeking in 10 SAFE Model pilot intervention and 4 control schools. At endline, the study intends to: 2. Assess post -intervention knowledge, perceptions, attitudes, agency, and intentions/behaviors related to mitigating risk exposure to child sexual abuse and exploitation: including reporting and help-seeking in 10 SAFE Model pilot intervention and 4 control schools. 3. To examine the extent to which the activities are implemented according to the SAFE model. 4. Assess the extent to which SAFE intervention is relevant to addressing the CSA problem. 5. Assess whether the SAFE model is contextually sustainable.
Uganda 2024-03-27 18:30:26 2027-03-27 Social Science and Humanities Non-Clinical Trial Non-degree Award
Damalie Nalwanga
ID: UNCST-2021-R013217
 Understanding, knowledge and attitudes of caregivers about the impact of HIV on the development and behavior of children of school-going-age
REFNo: HS3884ES

3. What are the caregivers’ attitudes about the impact of HIV on the development and behavior of children of school-going-age,2. What do caregivers know about the impact of HIV on the development and behavior of children of school-going-age,1. What is the caregivers’ understanding of the impact of HIV on the development and behavior of children of school-going-age,To explore caregivers’ understanding, knowledge and attitudes about the impact of HIV on the development and behavior of children of school-going-age,
 Uganda 2024-03-27 18:22:42 2027-03-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Edgar Mulogo Mugema
ID: UNCST-2023-R008170
 Artemisinin Resistance in Africa: its emergence and evolution in Rwanda and surrounding countries
REFNo: HS3549ES

• 1A will map the regional distribution and define the origins of 561H in Rwanda and neighboring regions in other countries. • 1B will define regional parasite population structure and migration routes that will impact the spread of 561H. • 1C will derive estimates of the selection coefficient for 561H and characterise associated community and infection-related (e.g. polyclonality, known partner drug resistance mutations, within-host relatedness) risk factors.,
 Uganda 2024-03-27 13:58:48 2027-03-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Clemensia Nakabiito
ID: UNCST-2022-R011396
 Viiv Protocol 221163: Long-Term Follow-Up of CAB LA for Participants in HPTN 083 and HPTN 084 CAB PrEP Studies at Risk of HIV Acquisition.
REFNo: HS3752ES

Primary Objectives
To describe new HIV infections in adult and adolescent participants at risk of HIV acquisition included in the HPTN 083 and HPTN 084 studies and their associated sub-studies.


Secondary Objectives
To describe any serious adverse events (SAEs), Grade 3 and Grade 4 ISRs and AEs leading to withdrawal in adult and adolescent participants included in the HPTN 083 and HPTN 084 studies and their associated sub-studies.

 Uganda 2024-03-26 18:05:15 2027-03-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Gertrude Nanyonjo Gawaya
ID: UNCST-2022-R005857
 Understanding end-user preferences and determining relative product positioning of new and emerging HIV prevention products (LAI-PrEP, bNAbs and HIV vaccines): Development and implementation of a Discrete Choice Experiment among at-risk populations in India and Uganda to inform product development and delivery
REFNo: SS2333ES

Objective 1: To explore and understand end-user preferences for HIV prevention options to design elicitation research (designing DCE)
 To identify key attributes (product and delivery site characteristics), and levels (options within a characteristic) through community key stakeholder consultations.
 To validate the product attributes and levels in consultation with representatives of potential end-users, non-governmental organisations (NGOs) and community-based organisations (CBOs), and government officials/policymakers for designing preference elicitation research.

Objective 2: To identify end-user preferences for HIV prevention options through elicitation research (DCE implementation)
 To quantify the strength of participants’ preferences.
 To determine the relative product positioning.

Objective 3: To understand decision-making process involved in choice of products among DCE participants

Uganda 2024-03-26 17:26:24 2027-03-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Proscovia Ntakyo Renzaho
ID:
Evaluation of sustainable intensification models for food and nutrition security of small holder households in southwestern highlands of Uganda
REFNo: SS1886ES

3. To understand the interaction effects between livestock and crop intensification on crop productivity in south western highland in Uganda4. To assess the effects of interrelated interventions in crop -livestock production on household food and nutrition security
 Uganda 2024-03-26 16:18:44 2027-03-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Dr. Gad  Ndaruhutse Ruzaaza
ID: UNCST-2023-R006987
 Perceptions of a point-of-use water filtration device among individuals of the Kashongi Community
REFNo: HS3490ES

to explore their perceptions of a point-of-use filtration device made using plant matter for filtration,to explore participants’ perceptions of the impact of water quality on their quality of life and the impact of water on their and their family’s health. ,
 Uganda 2024-03-26 15:36:54 2027-03-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Terence Odoch
ID: UNCST-2022-R010584
 eRabies – on the way to rabies elimination in Uganda: pilot mixed studies in Kampala, Kyegegwa and Soroti
REFNo: HS3463ES

a) To determine the benefits and potential barriers to the use of using an integrated One Health rabies surveillance form in Kampala, Kyegegwa and Soroti districts in Uganda. b) To determine the feasibility of implementing an integrated One Health rabies surveillance form in Kampala, Kyegegwa and Soroti districts in Uganda. c) To investigate the effectiveness of tailored community educational materials on enhancing knowledge and reduction of number of dog bites in Kampala, Kyegegwa and Soroti districts in Uganda. d) To determine barriers to and enablers of responsible dog ownership and canine rabies elimination in Kampala, Kyegegwa and Soroti districts in Uganda. e) To test the applicability of static point, school-based, mixed campaign with livestock health activities and mixed campaigns with human health activities rabies vaccination strategies in Kampala, Kyegegwa and Soroti districts in Uganda. f) To determine the influence of static point, school-based, mixed campaign with livestock health activities and mixed campaigns with human health activities rabies vaccination strategies on vaccination coverage in Kampala, Kyegegwa and Soroti districts in Uganda. g) Evaluate the effectiveness of the eRabies project interventions towards realising canine rabies elimination. h) To assess costs of the different components of the eRabies project and the cost-effectiveness of different Post-Exposure Prophylaxis (PEP) scenarios.
 Uganda 2024-03-26 15:30:41 2027-03-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
GRACE KANSIIME
ID: UNCST-2019-R000380
 COMPREHENSIVE APPROACH TO HYPERTENSION IMPROVEMENT IN RURAL UGANDA (CHIRU)
REFNo: HS3770ES

1: To determine the prevalence of hypertension among community residents in a rural population

2: To assess hypertension knowledge among adults in rural south-western Uganda

3: To assess healthcare providers’ knowledge regarding hypertension management in rural southwestern Uganda

4: To evaluate whether an evidence-based multicomponent intervention to manage hypertension can be implemented in rural Uganda.

 Uganda 2024-03-25 12:44:13 2027-03-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JULIET MWANGA-AMUMPAIRE
ID: UNCST-2022-R009420
 Catalyzing Artificial intelligence for Pediatric Tuberculosis Research (CAPTURE) Consortium in a project aimed at developing a chest X-ray (CXR) artificial intelligence (AI) algorithm for intrathoracic
REFNo: HS3921ES

The overall goal is to develop a CXR AI algorithm for intrathoracic TB that can be used for triage and/or diagnosis in children less than 15 years. ,
 Uganda 2024-03-25 12:38:18 2027-03-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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