Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Catherine Mwesigwa
ID: UNCST-2019-R000988
 Commercial Baby Food Consumption and Complementary Feeding Practices in Kampala
REFNo: HS1784ES

To explain the motivations for use of commercial baby foods among caregivers of infants and young children between 6-36 months in Kampala,To determine the proportion of caregivers that use commercial baby foods among infants and young children between 6-36 months in Kampala ,To determine the level of commercial baby food use for complementary feeding and the associated factors in an urban/peri-urban Ugandan sub-population of caregivers of infants and young children between 6-36 months in Kampala. ,
 Uganda 2021-12-02 2024-12-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Rhoda Wanyenze
ID: UNCST-2021-R013352
 Assessment of the HIV/AIDS legal, regulatory, and policy environment for key populations in Uganda
REFNo: HS1925ES

5 To develop recommendations on how the legal and policy framework affecting Key Populations can be improved to promote an enabling legal environment for the national response to HIV, particularly for key populations. ,4 To determine the extent to which the legal framework protects rights and promotes an enabling legal environment for the national response to HIV, particularly for people living with and affected by HIV and key populations. ,3 To analyze access to justice and law enforcement on HIV and human rights among key population and key service providers, access to legal support services, and law enforcement mechanisms. ,2 To assess the critical human rights issues affecting key populations and the extent to which the current environment addresses these.,1 To analyze existing HIV, health, and other related laws, regulations, and policy initiatives that impact the HIV response among key and priority populations in Uganda.,
 Uganda 2021-12-02 2024-12-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Robert Ssekitoleko
ID: UNCST-2019-R001716
 Laparoscopic Cases Database
REFNo: HS1909ES

The second aim of the study is to use this data in a future project examining new low-cost laparoscopic equipment. ,The first aim of the study is to compare laparoscopic practices in several countries. ,This study aims to examine current laparoscopic practices in Uganda and the United States.,
 Uganda 2021-12-02 2024-12-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eugene Ruzagira
ID: UNCST-2023-R008282
 Validating a 10-minute instrument-free prototype HIV p24/p37 assay for early infant diagnosis
REFNo: HS1854ES

Objectives of the research project:

Primary objectives
1. To determine the sensitivity of a novel instrument-free HIV p24 PoC assay
2. To determine the specificity of a novel instrument-free HIV p24 PoC assay
3. To determine the accuracy of a novel instrument-free HIV p24 PoC assay
4. To determine the positive predictive value of a novel instrument-free HIV p24 PoC assay
5. To determine the negative predictive value of a novel instrument-free HIV p24 PoC assay

Secondary objective
1. To determine the agreement of the novel instrument-free HIV p24 PoC assay results between two independent laboratory technicians.

15. Brief outline of research study design/methods:

 Uganda 2021-12-02 2024-12-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ayiorwoth Harriet
ID:
Exploring academic-practitioner knowledge sharing in higher education institutions: A study of Uganda Management Institute
REFNo: SS1102ES

1. Explore the benefits that UMI academic staff and practitioners gain from sharing knowledge. ,1. Find out how UMI academic staff and practitioners address the challenges that they face in sharing knowledge. ,Establish the challenges that UMI academic staff and practitioners face in sharing knowledge,Explore how UMI academic staff and practitioners share knowledge,The purpose of this study is to explore and gain an in-depth understanding of academic-practitioner knowledge sharing at UMI,
 Uganda 2021-12-02 2024-12-02 Social Science and Humanities Non-Clinical Trial Degree Award
Alfred Ecega Guli
ID:
HUMANITARIAN FOOD ASSISTANCE AND NUTRITION OUTCOMES AMONG CHILDREN UNDER FIVE YEARS IN UGANDA: A CASE OF SELECTED REFUGEE SETTLEMENTS IN WEST NILE.
REFNo: HS1912ES

1. What is the effect of food in-kind assistance on the nutrition outcomes among children under five years in selected refugee settlements in West Nile? 2. What is the effect of the cash-based transfer on the nutrition outcomes among children under five years in selected refugee settlements in West Nile? 3. What is the influence of agricultural inputs support on the nutrition outcomes among children under five years in selected refugee settlements in West Nile? 4. What is the effect of nutritional factors on humanitarian food assistance and nutrition outcomes among children under five years of age in selected refugee settlements in West Nile?
 Uganda 2021-12-02 2024-12-02 Medical and Health Sciences Non-Clinical Trial Degree Award
michael taylor halford
ID:
Dry Rifting in the Albertine -Rhino graben (DRIAR)
REFNo: NS260ES

To conduct geological investigation of faulting associated with continental rifting in the magma poor rift environment in the northernmost western branch of the East African Rift System.
 USA 2021-12-01 2024-12-01 Natural Sciences Non-Clinical Trial Degree Award
David  Sam Lackland
ID:
The psychological well-being of school-age South Sudanese children living in a refugee camp in Uganda
REFNo: SS938ES

RATIONALE
To the best of our knowledge, there are few studies trying to understand how South Sudanese refugee children thrive in settlements in Uganda, limiting the insight into their overall psychological well-being. Therefore, this study seeks to obtain a better understanding of how South Sudanese school-age refugee children experience their life in a refugee settlement in Northern Uganda.
The forced displacement of children implicates coping with and adapting to scenarios and situations that can be detrimental to a child’s normal development and well-being. To understand how children cope with the overall forced migration experience can contribute to find solutions to mitigate or reduce the potentially negative impact it has on children’s psychological well-being and mental health. By improving the knowledge about children’s experiences in refugee settlements, this study ultimately wishes to contribute with evidence that can facilitate the design and implementation of children friendly activities and environments in refugee settlements.
OBJECTIVES
In order to achieve the overarching aim mentioned before, this study plans to:
• observe how children play and socialize with each-other;
• understand how children learn in the refugee camp;
• explore how children cope emotionally with the different challenges caused by forced migration.
 Norway 2021-12-01 2024-12-01 Social Science and Humanities Non-Clinical Trial Degree Award
Macreen Mudoola
ID:
HRL Mid term and end of program evaluation protocol
REFNo: HS1701ES

to assess the progress of the project
 Uganda 2021-12-01 2024-12-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ezekiel Mupere
ID: UNCST-2021-R012739
 Enhancing Integrated Management of Acute Malnutrition with Family MUAC and Implementation Science in West Nile Region in Uganda - Implementation Guideline Research Proposal
REFNo: HS1828ES

5. To assess the impact of IMAM Family MUAC on access, coverage of OTC and ITC and quality of care.,4. To determine the retention level of family caregivers and VHTs in detection and referral of children with acute malnutrition.,3. To determine the effectiveness of IMAM Family MUAC in detection and referral of acute malnutrition ,2. To assess the barriers and facilitators of IMAM Family MUAC implementation in in health facilities and communities in five districts in West Nile,1. To determine the uptake of IMAM Family MUAC in health facilities and communities in five districts in West Nile,To establish the feasibility and evaluation of the implementation process and effectiveness of IMAM Family MUAC to improve access, coverage, and quality of care in OTC and ITC services,
 Uganda 2021-12-01 2024-12-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sina Kulwijira Sosthenes
ID:
Proportion of episiotomy and factors associated with episiotomy among mothers delivering at Mbarara regional referral hospital
REFNo: HS1552ES

To determine proportional of episiotomy and factors associated with episiotomy among mothers delivering at Mbarara regional referral hospital
 2021-11-30 2024-11-30 Medical and Health Sciences Non-Clinical Trial Degree Award
Muhmood Kiryowa Haruna
ID:
Periodontal disease in diabetic patients attending Kiruddu Referral Hospital, Kampala: Prevalence, Factors and Association with Glycemic control and Insulin resistance
REFNo: HS1853ES

1) To determine the prevalence and factors associated with periodntal disease in patients with diabetes mellitus
2) To determine the bacteria associated with periodntal disease in patients with diabetes mellitus
3) To determine the association between periodntal disease and insulin resistance in patients with diabetes mellitus
 Uganda 2021-11-30 2024-11-30 Medical and Health Sciences Non-Clinical Trial Degree Award
Victoria Namuggala Flavia
ID: UNCST-2019-R000991
 Young Women and Men’s Aspirations and Resilience: Prospects for Livelihoods, Employment and Accountability before, during and beyond COVID – 19
REFNo: SS1093ES

The overall objective of this project is to explore and interrogate the aspirations and resilience of young women and men in Africa; how these may or may not have shifted through the COVID-19 crisis and the implications presented for public policy in Africa with case studies in Ethiopia, Ghana, Kenya, Nigeria, Rwanda, Senegal and Uganda. Specific objectives are to:
1. Examine Ugandan young women and men’s aspirations for their futures.
2. Identify and analyse gender and social norms that guide the lives and aspirations of young men and women in Uganda.
3. Establish whether young women and men’s aspirations have changed with the advent of COVID-19.
4. Analyse what the young women and men are experiencing in their lives and livelihoods in a COVID-19 world.
5. Determine the extent to which the various provisions, regulations and policies in the study countries are aligned with young women and men’s aspirations and ideas about what they see themselves doing in the future.
6. Document lessons learned about the adaptability and resilience of young women and men’s aspirations.

Uganda 2021-11-30 2024-11-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
Stephen Okoboi
ID: UNCST-2019-R001356
 Controlled Trial of Game Changers: A Group Intervention to Train HIV Clients to be Change Agents for HIV Prevention in Uganda
REFNo: HS1896ES

1. To conduct a fully powered RCT of Game Changers to test intervention effects on the primary outcomes of increased HIV testing, reduced condomless sex, and decreased enacted HIV stigma among social network members of participating PLWH.
2. To test intervention effects on the secondary outcomes of reduced internalized HIV stigma, increased HIV serostatus disclosure, and increased viral load suppression among participating PLWH, and PrEP uptake among their social network members.
3. To examine whether increased HIV prevention advocacy by PLWH mediates intervention effects on their social network members’ increased HIV testing and condom use, and whether increased HIV disclosure by PLWH mediates intervention effects on social network members’ reduced HIV stigma.
4. To conduct a cost-effectiveness analysis of the intervention.
We will recruit 210 PLWH, randomizing 105 to the intervention and 105 to a no-intervention control
Uganda 2021-11-30 2024-11-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jenna Amlani Nahid
ID:
PATHWAYS FOR AGILE IMPLEMENTATION: IDENTIFYING THE ACTIVE ELEMENTS OF RAISING VOICES’ GOOD SCHOOL TOOLKIT
REFNo: SS1060ES

to elicit feedback from stakeholders on the program and specific activities to improve the GST ,to understand which aspects of the GST most important for changing relationships within schools and ultimately reducing violence against children ,
 Canada 2021-11-29 2024-11-29 Social Science and Humanities Non-Clinical Trial Non-degree Award
Kamya Moses
ID: UNCST-2020-R014203
 Social-spatial networks and Tuberculosis Infection in Children and Youth in Rural Uganda (SONET)
REFNo: HS1844ES

General Objective
To characterize, on a population-level, where and from which social network youth acquire TB infections and to assess variations throughout stages in the early life-course (early childhood: 1-5 years; school-age: 6-11 years; adolescence: 12-18 years).


Uganda 2021-11-29 2024-11-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Arnold Moses  Okello Moses
ID:
Addressing Child Trafficking and Slavery in Uganda (ACTS)
REFNo: SS871ES

1. The Standards of Care (SOC) workstream seeks to develop evidence-based nationwide standards of care for survivors and victims of trafficking and slavery. This will involve a desk-based evidence review, online surveys, workshops with the staff of civil society organisations, and analysis of survivor workshop and monitoring and evaluation data collected by project lead Hope for Justice.
2. The Network Strengthening (NSing) component seeks to engage key stakeholders to strengthen internal technical capacity for the Coalition against Trafficking in Persons in Uganda (CATIPU). The aim of this workstream is to increase the capacity of this network of counter-trafficking civil society organisations to improve prevention, protection prosecution and partnership outcomes and capacity for increased collaboration with wider government structures. Therefore, the Unit of Analysis is the network (see Section 12, page 8 below for more detail).

 Uganda 2021-11-26 2024-11-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Susan Babirye
ID: UNCST-2021-R013201
 Analysis of formal and informal institutions of socializing places and their role in shaping vulnerability to HIV: a case of young people (15-24 years) working in socializing places in Uganda
REFNo: HS1536ES

This study aims to analyze formal and informal institutions of socializing places and their role in shaping vulnerability to HIV using a case of YPSP in Uganda. The specific objectives are:
1. To profile socializing places in Uganda and the young people who work in such places
2. To explore the formal and informal institutions of socializing places and their influence on HIV risk and vulnerability of YPSP
3. To determine how YPSP navigate workplace rules and procedures that expose them to HIV risk and vulnerability
4. To explore compliance gaps of the formal and informal institutions of socializing places with the existing laws and opportunities for reducing youth vulnerability to HIV in socializing places

 Uganda 2021-11-25 2024-11-25 Medical and Health Sciences Non-Clinical Trial Degree Award
Flavia Matovu Kiweewa
ID: UNCST-2021-R013337
 PURPOSE 1: GS-US-412-5624/ A Phase 3, Double-Blinded, Multicenter, Randomized Study to Evaluate Safety and Efficacy of Twice Yearly Long-Acting Subcutaneous Lenacapavir, and Daily Oral Emtricitabine/Tenofovir Alafenamide for Pre-Exposure Prophylaxis in Adolescent Girls and Young Women at Risk of HIV Infection. Version 2.0, dated 10 March 2021.
REFNo: HS1920ES

1. Primary Objectives i) To evaluate the efficacy of LEN for HIV PrEP in AGYW at risk of HIV infection. ii) To evaluate the efficacy of F/TAF for HIV PrEP in AGYW at risk of HIV infection. 2. Secondary Objectives/ end points i) To compare the efficacy of LEN with F/TDF for HIV PrEP in AGYW at risk of HIV infection. ii) To evaluate the efficacy of LEN for HIV PrEP in AGYW at risk of HIV infection in participants adherent to LEN. iii) To evaluate the efficacy of F/TAF for HIV PrEP in AGYW at risk of HIV infection in participants adherent to F/TAF. iv) To compare the efficacy of F/TAF with F/TDF for HIV PrEP in AGYW at risk of HIV infection. v) To evaluate the safety and tolerability of LEN, F/TAF, and F/TDF for HIV PrEP in AGYW at risk of HIV infection. vi) To evaluate the safety and tolerability of LEN and F/TAF for HIV PrEP in AGYW ≥ 16 to < 18 years of age who have sex with male partners and are at risk for HIV infection. 3. Exploratory objectives i) To assess the adherence rate to LEN as assessed by on-time LEN injection ii) To assess LEN plasma levels iii) To assess the adherence rate to F/TAF and F/TDF using intracellular TFV-DP levels in DBS. iv) To evaluate the acceptability of a once every 26 weeks LEN injection for HIV PrEP in AGYW at risk of HIV infection. v) To assess LEN plasma levels during pregnancy. vi) To explore concentrations of hormonal contraceptives in LEN participants.
Uganda 2021-11-25 2024-11-25 Medical and Health Sciences Clinical Trial Non-degree Award
Julie Teichroeb Annette
ID:
Social decision-making in Angolan colobus (Colobus angolensis ruwenzorii) and vervet monkeys (Chlorocebus pygerythrus) at Lake Nabugabo
REFNo: NS131ES

Understanding the effects of social constraints on group size and composition, movements, and foraging decisions.
 Canada 2021-11-24 2024-11-24 Natural Sciences Non-Clinical Trial Non-degree Award
Kamya Moses
ID: UNCST-2020-R014203
 Enhancing immunity to malaria in young children with effective chemoprevention
REFNo: HS1763ES

To compare the incidence of malaria from 4 weeks to 4 years of age among children born to mothers randomized to receive intermittent preventative therapy in pregnancy (IPTp) with monthly sulfadoxine pyrimethamine (SP) alone, monthly DP alone, or both monthly SP+DP.

To compare the incidence of malaria from 2-4 years of age among children randomized to receive IPT in childhood (IPTc) with monthly DP from 8 weeks to 1 year of age vs. monthly DP from 8 weeks to 2 year of age vs. no IPTc.

To compare innate and adaptive effector and regulatory responses between children randomized to different IPT arms.

Uganda 2021-11-24 2024-11-24 Medical and Health Sciences Clinical Trial Non-degree Award
Emmanuel Viga Emmanuel
ID:
MORAL AND SOCIAL DIMENSIONS OF ACCOUNTABILITY IN CIVIC HUMANITARIANISM: RELATIONAL AID AMONGST SOUTH SUDANESE REFUGEES IN UGANDA
REFNo: SS832ES

This research will majorly attempt to answer the question How is accountability of relational aid in civic humanitarianism conceptualized and managed in protracted crisis. This will be achieved by answering the following sub questions:- 1. What differentiates civic humanitarianism from mainstream humanitarian actors? 2. What is relational aid within civic humanitarianism? and how is accountability understood within the concept of relational aid? 3. What are the accountability practices in civic humanitarian aid? 4- How do different accountability forms influence aid delivery?
Uganda 2021-11-23 2024-11-23 Social Science and Humanities Non-Clinical Trial Degree Award
DAN NYEHANGANE
ID:
CYCLOTIDES FROM MEDICINAL PLANTS OF UGANDA: SELECTED SOURCES, ANTIBACTERIAL ACTIVITY, AND CYTOTOXICITY
REFNo: NS258ES

Primary Objective: To identify cyclotides from selected medicinal plants in Uganda and establish their antibacterial activity and cytotoxicity, in order to provide a basis for their medical application in Uganda.

Specific Objectives
1.To determine the presence and quantities of cyclotides in different parts of selected medicinal plant species from selected families reported to express cyclotides and are used to treat bacterial infections in Uganda.
2.To characterize the activity of cyclotides from Ugandan plants in relation to sequence, size and structure
3.To determine antibacterial activities of cyclotides isolated from the different plant species stratified by the plant part extracted and season of harvesting the plant.
4.To determine the cytotoxic effect of the most active antibacterial cyclotide on mammalian cells
5.To determine the synergistic activity of the most active cyclotides against bacterial strains by using combinations of cyclotides from different plant species
6.To establish the anti-biofilm and immunomodulatory activity of the most active anti-bacterial cyclotides



 Uganda 2021-11-23 2024-11-23 Natural Sciences Non-Clinical Trial Degree Award
Brenda McCollum
ID:
Muslims and Islam in Buganda, ca. 1900 - 1962
REFNo: SS950ES

I seek to examine the Muslim experience of colonialism in the Kingdom of Buganda.
USA 2021-11-23 2024-11-23 Social Science and Humanities Non-Clinical Trial Degree Award
Rebecca Nalwanga Nalwanga
ID:
Exploring the Social and Institutional Dimensions of Disability in Primary Education: The Case of Inclusive Development in Uganda
REFNo: SS985ES

This research project aims to better understand the relationship between social development and disability in low-income countries. To achieve this objective, the research project will focus on how the experiences and positionality of primary school learners with a disability intersect with social development, education and democracy, and how these intersections can inform policy and practices to advance social, economic and political development in a low-income country such as Uganda.
 Uganda 2021-11-22 2024-11-22 Social Science and Humanities Non-Clinical Trial Degree Award
Faith Masette Bisikwa
ID:
Exploring Classroom Assessment Practices and its Impact on Preservice Teachers’ self-efficacy in a selected Primary Teachers college, Uganda
REFNo: SS993ES

I used questions instead of objectives
Main Question; How do tutors’ classroom assessment practices impact preservice teacher’s self-efficacy?
Subsidiary questions;
1.What are the common classroom assessment practices in Ugandan Primary teachers’ colleges?

2.How is classroom assessment, practiced in this PTC?

3.What is the relationship between assessment practices and preservice teacher’s self-efficacy?
4.How best can classroom assessment practices be done in PTCs to improve Preservice teachers’ self-efficacy?


 Uganda 2021-11-22 2024-11-22 Social Science and Humanities Non-Clinical Trial Degree Award
Cissy  Kityo
ID: UNCST-2021-R013663
 ACTIV-2/A5401: Adaptive Platform Treatment Trial for Outpatients with COVID-19 (Adapt Out COVID)
REFNo: HS1813ES

1.1 Co-Primary Objectives 1.1.1 Phases II and III: To evaluate safety of the investigational agent. 1.1.2 Phase II: To determine efficacy of the investigational agent to reduce the duration of COVID-19 symptoms through study day 28. 1.1.3 Phase II: To determine the efficacy of the investigational agent to increase the proportion of participants with nasopharyngeal (NP) SARS-CoV-2 RNA below the lower limit of quantification (LLoQ) at study days 3, 7, and 14. 1.1.4 Phase III: To determine if the investigational agent will prevent the composite endpoint of hospitalization due to any cause or death due to any cause through study day 28. Hospitalization is defined as ≥24 hours of acute care, in a hospital or similar acute care facility, including Emergency Rooms or temporary facilities instituted to address medical needs of those with severe COVID-19 during the COVID-19 pandemic. 1.2 Secondary Objectives 1.2.1 Phases II and III: To determine whether the investigational agent reduces a COVID-19 Severity Ranking scale based on COVID-19-associated symptom burden (severity and duration), hospitalization, and death, through study day 28. 1.2.2 Phase II and III: To determine whether the investigational agent reduces the progression of COVID-19-associated symptoms. 1.2.3 Phase II and III: To determine if the investigational agent reduces levels of SARS-CoV-2 RNA in NP swabs. 1.2.4 Phase III: To determine the efficacy of the investigational agent to increase the proportion of participants with NP SARS-CoV-2 RNA below the LLoQ at study day 3. 1.2.5 Phase II: To determine the pharmacokinetics of the investigational agent. 1.2.6 Phase II: To determine efficacy of the investigational agent to obtain pulse oximetry measurement of ≥96% through day 28. 1.2.7 Phase III: To determine if the investigational agent will prevent the composite endpoint of hospitalization due to any cause or death due to any cause through study week 72. 1.2.8 Phase III: To evaluate if the investigational agent reduces the time to sustained symptom resolution through study day 28.
Uganda 2021-11-22 2024-11-22 Medical and Health Sciences Clinical Trial Non-degree Award
Francis Ssali
ID: UNCST-2021-R012134
 A Phase 2, Open-label, Single-arm, Multicentre Study to Evaluate the Pharmacokinetics, Safety, Tolerability, and Efficacy of Switching to RPV Plus Other ARVs in HIV-1-infected Children (Aged 2 to less than 12 years) who are Virologically Suppressed (TMC278HTX2002)
REFNo: HS1815ES


Primary Endpoints
• Area under the plasma concentration-time curve from the time of administration up to 24 hours post-dose of RPV, as derived from the intensive PK assessments.
• Incidence of grade 3/4 AEs, SAEs, HIV-related events (including acquired immune deficiency syndrome [AIDS]-defining illnesses and Stage-3-defining Opportunistic Illnesses in HIV Infection), and AEs leading to discontinuation of study intervention through 24 weeks of study treatment.

Secondary Endpoint
• Incidence and severity of AEs/HIV-related events and their relatedness to RPV through 24 and 48 weeks of study treatment.
• Change from baseline Movement.
• Viral genotype at the time of virologic failure through 24 and 48 weeks of study treatment.
• Treatment adherence, as assessed by the Pediatric European Network for the Treatment of AIDS (PENTA) adherence questionnaire and by study intervention accountability, through 24 and 48 weeks of study treatment.

 Uganda 2021-11-22 2024-11-22 Medical and Health Sciences Clinical Trial Non-degree Award
Jerome  Kabakyenga Kahuma
ID: UNCST-2021-R013729
 The A-Lite vein locator: “a non-invasive assistive medical device designed to improve vein visibility among patients requiring intravenous therapy.”
REFNo: HS1547ES

Main Objective
1. To assess the efficacy, safety and impact of using an assistive medical device to aid vein visibility among patients requiring intravenous therapy.

Specific Objectives
1. To assess the safety and efficacy of the A-Lite vein locator among 10 adults in Uganda.

2. To investigate non-inferiority by assessing the performance of the A-Lite vein locator with respect to the existing standard of care among 48 adolescents in Uganda.

3. To determine the effectiveness of using the A-Lite vein locator for improving vein visibility among 156 children requiring intravenous cannulation in Uganda.
 Uganda 2021-11-19 2024-11-19 Medical and Health Sciences Clinical Trial Non-degree Award
Clare Tanton Tanton
ID:
Taking the Good School Toolkit to scale
REFNo: SS1035ES

The aim of the project is to determine the feasibility and acceptability of using Regional Resource Persons to deliver the Good Schools Toolkit in primary and secondary schools in Uganda and to relate markers of implementation to intermediate outcomes in teachers.
The specific objectives are:
1. To determine whether implementation of the Good Schools Toolkit through Regional Resource Persons can be done with fidelity and whether it is associated with attitudes towards violence against children and markers of school operating culture among teachers.
2. To understand Teacher Protagonists’ motivations, their perceptions of their role and how these evolve during intervention implementation. To understand Teacher Protagonists’ experiences and opinions of intervention mode of delivery and the support they receive from Regional Resource Persons and school administration, and their views on the main successes and challenges of this approach.
3. To understand the experiences of Regional Resource Persons in supporting schools and at different stages of intervention implementation. To understand Regional Resource Persons’ perceptions of the main successes and challenges they face during intervention implementation and how these challenges might be overcome.
4. To explore how the attitudes and behaviours of the Regional Resource Persons evolve following Good Schools Toolkit training and during their role supporting schools, and how this correlates with their performance.
5. To understand teachers’ experiences returning to school after prolonged COVID-related closures

 UK 2021-11-19 2024-11-19 Social Science and Humanities Non-Clinical Trial Non-degree Award
ANGELLA MUSIIMENTA
ID: UNCST-2021-R013297
 My Mobile Wallet: An Intervention to Support Access to Tuberculosis Care and medication Adherence in Rural Uganda
REFNo: HS1688ES

Assess the refined My Mobile Wallet intervention for larger scale feasibility, acceptability, and impact on TB treatment adherence and clinical outcomes. We will randomize 162 newly diagnosed TB patients (1:1:1) to SMS texts + incentives Arm A, SMS texts only B, and control Arm C (standard clinic-based TB care); follow-up will be the 6 month-treatment period. Feasibility and acceptability will be assessed per above. Impact will be based on electronically monitored medication adherence (primary), as well as treatment completion, clinic attendance, cure, and mortality (secondary).,Refine the My Mobile Wallet intervention. We will adapt the intervention to address any feasibility and accessibility issues raised in R21 findings. We will then pilot test the refined version of the intervention in 10 TB patients over two months of treatment to ensure optimal functionality. ,Assess the initial feasibility and acceptability of My Mobile Wallet. Forty patients with newly diagnosed TB will use My Mobile Wallet over their 6-month course of treatment. Feasibility will be assessed by appropriate receipt of the cash transfers and SMS texts, and intervention functionality. Acceptability will be assessed using System Usability Scale [53] and interviews based on the Unified Theory of Acceptance and Use of Technology [54].,Determine the optimal design and develop My Mobile Wallet as an intervention to support TB medication adherence. Through client-centered approaches, we will iteratively conduct focus group discussions with up to 30 TB patients to develop an optimal My Mobile Wallet intervention.,
 Uganda 2021-11-19 2024-11-19 Medical and Health Sciences Clinical Trial Non-degree Award
Noeline Nakasujja
ID: UNCST-2019-R001428
 The impact of the COVID-19 pandemic and its response on the mental health of people with pre-existing mental conditions in Uganda.
REFNo: HS1781ES

5. To explore the experiences and views of people with SMI, their families/caretakers and mental health clinicians regarding the MMHC,4. To assess the effectiveness of an outreach mobile mental health clinic (MMHC)7 initiative to mitigate the care and messaging gap for people with SMI during the Covid-19 pandemic and its response.,3. To explore the experiences and viewsof people with SMI and their families/caretakers regarding COVID -19 and its response ,2. To assess the effect of COVID -19 and its response on access to care for people with SMI ,1. To assess the effect of COVID -19 and its response on the mental health of people with SMI ,
 Uganda 2021-11-18 2024-11-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jack Rugasira
ID:
GREEN SUPPLY CHAIN PRACTICES AND ENVIRONMENTAL SUSTAINABILITY: A CASE OF SELECTED UGANDA MANUFACTURERS ASSOCIATION ENTITIES IN KAMPALA
REFNo: NS308ES

i. To determine the relationship between green sourcing and resource use efficiency in Kampala district.
ii. To determine the impact of green manufacturing on ecological balance in Kampala district.
iii. To assess the relationship between green transportation and availability of clean air and water in Kampala district.
iv. To determine the relationship between reverse logistics and wetland management in Kampala district

 Uganda 2021-11-18 2024-11-18 Natural Sciences Non-Clinical Trial Degree Award
Thereza Piloya Were
ID: UNCST-2019-R000491
 The Relation Between Mean Glucose and HbA1c in Ugandan Children and Youth with T1D: An Observational Study
REFNo: HS606ES

PRIMARY OBJECTIVES
1. To determine the relation between laboratory-measured HbA1c and mean glucose as measured by continuous glucose monitoring (assessed over 10-14 days per sensor period).
2. To determine the consistency of the relationship between laboratory- measured HBA1C and the mean glucose using multiple measurements in Ugandan Children and youth.
3. To determine the relation between laboratory-measured HbA1c and factors known to impact red blood cell survival.
SECONDARY OBJECTIVE
To determine the relation between point-of-care HbA1c and mean glucose in this population.

 Uganda 2021-11-17 2024-11-17 Medical and Health Sciences Non-degree Award
Catherine Atuhaire
ID: UNCST-2021-R013090
 A multi-morbidity study of diabetes mellitus, hypertension and Postpartum depression among postnatal mothers (MMDHAPPD) in Mbarara city, Uganda
REFNo: HS1836ES

To explore the challenges and coping strategies of mothers suffering from these multiple morbidities in Mbarara city, Uganda,To compare the serum cortisol levels of mothers diagnosed with and without postpartum depression,To determine the prevalence of hypertension among mothers diagnosed with postpartum depression in Mbarara city, Uganda ,To determine the prevalence of diabetes among mothers diagnosed with postpartum depression in Mbarara city, Uganda ,To assess the association between postpartum depression and either diabetes, hypertension or both among mothers in Mbarara city, Uganda,To determine the prevalence of postpartum depression based on the DSM-5 among mothers in Mbarara city, Uganda,To investigate the association between PPD and diabetes / hypertension or both and to explore the challenges and coping mechanisms experienced by these mothers suffering from these multiple morbidities in Mbarara city, Uganda,
 Uganda 2021-11-17 2024-11-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Leevan Tibaijuka
ID: UNCST-2021-R012986
 Maternal comorbidities in pregnancy and post-delivery at Mbarara Regional Referral Hospital
REFNo: HS1734ES

3) To adapt a mobile application and assess the feasibility and acceptability of a pilot implementation of an intervention of sending appointments reminders and health education tips inform of SMS and pre-recorded voice messages to post-delivery women with co-morbidities to improve their compliance to follow-up appointments at MRRH. ,2) To compare the incidence of adverse maternal-fetal outcomes in women with and without medical co-morbidities and determine the predictors of adverse maternal-fetal outcomes among women admitted for delivery at MRRH. ,1) To determine the prevalence of and modifiable risk factors associated with medical comorbidities among pregnant and post-delivery women at MRRH.,To explore medical co-morbidities among pregnant and post-delivery women at Mbarara Regional Referral Hospital (MRRH),
 Uganda 2021-11-17 2024-11-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Janet SEELEY
ID:
African Prostate Cancer - Disparities in Outcomes in Uganda (APC-DOUG)
REFNo: HS1790ES

Aim/goal of study (General Objective)
The African Prostate Cancer - Disparities in Outcomes in Uganda (APC-DOUG) study aims to evaluate the health system, socioeconomic and clinical factors that impact public hospitals across Uganda to deliver affordable interventions that improve and reduce inequalities in prostate cancer outcomes.

1.6 Specific objectives
1. To evaluate the current structure and organisation of clinical care for prostate cancer
2. To understand the socio-economic, cultural and geographic barriers to accessing care

UK 2021-11-17 2024-11-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ALLAN BAGUMA
ID: UNCST-2021-R012022
 Effect of Covid-19 pandemic and national lockdown on utilization of childhood immunization services at Kisenyi health centre IV KCCA health facility in Kampala.
REFNo: HS1879ES

General Objective
To determine the effect of Covid-19 pandemic and national lockdown on utilization of childhood immunization services at Kisenyi health centre IV health facility in Kampala.
Specific Objectives
1. To determine the pre-lockdown childhood immunization coverage at Kisenyi health facility in Kampala.
2. To determine the coverage of child hood immunization at Kisenyi health facility in Kampala during the national lockdown.
3. To assess the barriers and facilitators of childhood immunization at Kisenyi health centre IV facility in Kampala during the covid 19 pandemic.
4. To determine the coverage of child hood immunization at Kisenyi health facility in Kampala post the national lockdown

 Uganda 2021-11-17 2024-11-17 Medical and Health Sciences Non-Clinical Trial Degree Award
Ritah Kigonya
ID:
Enhancing Livelihood Outcomes in Biodiversity offset Schemes in Uganda’s Oil and Gas Industry’s CSR Strategies
REFNo: SS332ES

The overall objective of the study is to enhance incorporation of people’s use and cultural values of biodiversity during the design and implementation of biodiversity offsets. The specific objects include; Objective 1: Mapping the extent of biodiversity offset projects and their effects on community livelihoods. Objective 2; Analyze the extent to which biodiversity-based livelihood compensation schemes (social offset schemes) attain their desire objectives. Objective 3; Use lessons from biodiversity-based compensation schemes to ascertain who to compensate, what to compensate and how to compensate them during implementation of biodiversity-based livelihoods
Uganda 2021-11-16 2024-11-16 Social Science and Humanities Non-Clinical Trial Degree Award
JOSAPHAT KAYOGOZA BYAMUGISHA
ID: UNCST-2019-R001680
 REPRODUCTIVE TRACT INFECTIONS AMONGST STUDENTS: ADDRESSING THE CHALLENGE AT MAKERERE UNIVERSITY
REFNo: HS1810ES

To determine the prevalence of RTIs among Makerere University students,To assess the Reproductive Tract Infections (RTIs) related knowledge, attitude and practices (KAP) of the Makerere University population.,To address the challenge of Reproductive Tract Infections amongst students by establishing the prevalence, knowledge of students towards RTIs and reducing the gap through use of youth friendly approaches.,
 Uganda 2021-11-15 2024-11-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
RACHAEL KULWENZA
ID:
EXPLORING THE TEACHING OF READING IN LOWER PRIMARY CLASSES IN KOCHEKA SUBCOUNTY, UGANDA. A CASE OF ONE GOVERNMENT PRIMARY SCHOOL.
REFNo: SS987ES

•To find out what teaching and learning approaches do teachers use to teach reading in the lower primary level. •To investigate how do the approaches that teachers use in teaching reading in lower primary levels impact the development of the reading competences of the children?
•To find out what opportunities and challenges exist when teaching reading to learners in the lower primary level?

 Uganda 2021-11-15 2024-11-15 Social Science and Humanities Non-Clinical Trial Degree Award
RICHARD EDEMA BAZIL
ID:
Investigating how teachers use mother tongue as a medium of instruction for lower primary mathematics
REFNo: SS1013ES

The objectives of the study are to establish: -
1. How the teachers are providing for the use of mother tongue as a medium of instruction during preparation for teaching and learning lower primary mathematics?
2. How the teachers are using mother tongue as a medium of instruction during teaching and learning processes of mathematics in P1 to P3?
3. The opportunities presented by the use of mother tongue in the teaching and learning of mathematics in P1 to P3?
4. The challenges the teachers face in the use of Mother tongue as a medium of instruction for mathematics in lower primary classless?

Uganda 2021-11-15 2024-11-15 Social Science and Humanities Non-Clinical Trial Degree Award
Arthur Bagonza
ID:
EFFECT OF COVID-19 ON PAEDIATRIC FEVER TREATMENT AMONG REGISTERED PRIVATE DRUG SELLERS IN EAST-CENTRAL UGANDA
REFNo: HS1729ES

1. To determine the effect of lock-down due to COVID-19 on treatment of children less than five years presenting with malaria,diarrhoea and pneumonia symptoms at registered private drug shops in Luuka district, East Central Uganda.

2. To explore perceptions of drug sellers and key stakeholders regarding treatment of children less than five years presenting with malaria,diarrhoea and pneumonia symptoms at registered private drug shops in Luuka district,East Central Uganda.

 Uganda 2021-11-15 2024-11-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Fatumo  Segun Adeyemi
ID:
Causal Relationship between Cardiometabolic traits and Chronic Kidney Disease in African Population.
REFNo: HS1730ES

1. To Identify genetic determinants of kidney function in continental Africa"
2. To investigate the predictive utility of Polygenic Risk Scores for Chronic Kidney disease in Africans.
3. To assess the causal effect of kidney function on cardiometabolic diseases using Mendelian Randomisation Approach.

 UK 2021-11-15 2024-11-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Geoffrey Beyihayo Akiiki
ID:
Native Chicken Project
REFNo: A154ES

To establish genetic markers associated with economic traits among indigenous chicken eco-types,To establish genetic and phenotypic parameter estimates for economic traits among indigenous chicken eco-types,To assess the genetic diversity of indigenous chickens eco-types based on mitochondrial DNA (mtDNA),To characterize indigenous chicken based on qualitative and quantitative phenotypic traits ,To characterize and identify genetic markers of egg and growth traits for selection of highly productive indigenous multipurpose chickens ,
 Uganda 2021-11-15 2024-11-15 Agricultural Sciences Non-Clinical Trial Degree Award
David Guwatudde
ID: UNCST-2021-R008522
 The Uganda Non-Communicable Diseases (NCD) Risk Factor Mobile Phone Survey - 2021
REFNo: HS1738ES

1.Evaluate the efficacy (as measured by the response rate), of conducting a mobile phone survey to collect data on the common NCD risk factors

2.Collect data on specific NCD disease conditions, and the self-reported NCD risk factors to support monitoring and evaluation of programs and policies in Uganda.

3.Generate comparable data from mobile phone surveys within Uganda over time.

4.Provide data to the Ministry of Health and other relevant ministries, and make recommendations on developing, improving, and enhancing prevention and response strategies to address NCDs and NCD associated disabilities in Uganda.
 Uganda 2021-11-15 2024-11-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Allan Kalyesubula Edward
ID: UNCST-2021-R012991
 The prevalence of oral diseases and their associated factors in children and adolescents attending the diabetes clinic at Mulago
REFNo: HS1799ES

1. To determine the prevalence of dental caries among children and adolescents attending the diabetes clinic at Mulago.
2. To determine the prevalence of periodontal diseases among children and adolescents attending the diabetes clinic at Mulago.
3. To determine the associated risk factors for dental caries among children and adolescents attending the diabetes clinic at Mulago.
4. To determine the associated risk factors for periodontal diseases among children and adolescents attending the diabetes clinic at Mulago
 Uganda 2021-11-15 2024-11-15 Medical and Health Sciences Non-Clinical Trial Degree Award
Adeodata Rukyalekere Kekitiinwa
ID: UNCST-2019-R000799
 BREATHER Plus: A randomized open-label 2-arm, 96-week trial evaluating the efficacy, safety and acceptability of short cycle (five days on, two days off) dolutegravir/tenofovir-based triple antiretroviral therapy (ART) compared to daily dolutegravir/tenofovir- based triple ART in virologically suppressed HIV-infected adolescents aged 12 to 19 years of age in sub-Saharan Africa, Version 2.0, Dated 18-Mar-2020; ISRCTN #: 85058577
REFNo: HS1822ES

Major Objective: A randomized open-label 2-arm, 96-week trial evaluating the efficacy, safety and acceptability of short cycle (five days on, two days off) dolutegravir/tenofovir-based triple antiretroviral therapy (ART) compared to daily dolutegravir/tenofovir-based triple ART in virologically suppressed HIV-infected adolescents aged 12 to 19 years of age in sub- Saharan Africa
Specific Objectives
To evaluate an innovative and contemporary ART strategy in HIV-infected adolescents to provide choice for young people facing life-long treatment. Output from this RCT will provide evidence on efficacy, safety and acceptability of a novel treatment approach in HIV-infected adolescents in sub-Saharan Africa
To evaluate the virological efficacy, safety, acceptability and Quality of Life of DTG-based Short-cycle Therapy with weekends off compared with Continuous Therapy with a DTG- based ART regimen
To optimize treatment for HIV-infected adolescents in sub-Saharan Africa

 Uganda 2021-11-15 2024-11-15 Medical and Health Sciences Clinical Trial Non-degree Award
Mvuyo Sikhondze Maqhawe
ID:
DIABETIC FOOT ULCERS: SURGICAL CHARACTERISTICS, TREATMENT MODALITIES AND SHORT-TERM TREATMENT OUTCOMES AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS1857ES

General Objective
To describe the surgical characteristics, treatment modalities and short-term treatment outcomes of diabetic foot ulcers at Mbarara Regional Referral Hospital.

Specific Objectives
1. To describe the surgical characteristics of diabetic foot ulcers observed at Mbarara Regional Referral Hospital.
2. To describe the treatment modalities of diabetic foot ulcers at Mbarara Regional Referral Hospital.
3. To document the short-term treatment outcomes of patients with diabetic foot ulcers at Mbarara Regional Referral Hospital.
 Eswatini 2021-11-15 2024-11-15 Medical and Health Sciences Non-Clinical Trial Degree Award
Sabine, Willemina, Johanna Luning
ID:
Gold Matters: Transformations to Sustainability in Artisanal and Small Scale Gold Mining in Uganda
REFNo: SS716ES

1. To consider whether a transformative approach toward sustainability can arise in Artisanal and Small Scale Gold Mining (ASGM).
2. To explore new notions of sustainability and transformations.
3. To contribute to a better understanding of the dynamic, heterogeneous reality of ASGM.
 Netherlands 2021-11-11 2024-11-11 Social Science and Humanities Degree Award
Jessica Perkins M
ID: UNCST-2021-R013564
 Perceptions of Social Norms and Personal Propensity to Engage in HIV Testing: A Mixed Methods Study and Intervention in Rural Uganda
REFNo: SS812ES

We propose a study to assess norms and perceptions about HIV prevention and related topics. This includes assessing village norms (i.e., the behaviours or attitudes of more than 50% of the adult population), perceived norms, how people form their perceptions, which social reference groups are the most meaningful, and the difference between actual norms and individuals’ perceptions of what most others do or believe. We will also examine whether perceptions are associated with personal behaviours and attitudes. Project 1 Aim: To engage in secondary analysis of quantitative data about perceived social norms and actual population norms around HIV prevention behaviours and related topics across different social reference groups. Aim 1: We will assess the prevalence of perceived and actual behavioural norms. We will do this both at the village-level and across various sociodemographic and health indicators. We will consider a behaviour the village norm if it is reported by more than 50% of adults. Aim 2: Because the parent study includes nearly all adults living in Nyakabare Parish, we can compare the actual village norm (assessed in Aim 1) to perceptions of the village norm. The parent study asked participants about their perceptions of what most other adults in the village do or think. Aim 3: Using the self-reported behaviours, attitudes, and norm perceptions, we will test whether individuals’ perceptions of what is normative is related to their personal attitudes and behaviours. Project 2 Aim: To use qualitative research methods to understand the nuances of HopeNet participants’ perceptions about local norms and design valid survey questions that elicit perceived social norms about HIV testing within different reference groups. Aim 1: Through in-depth interviews, scenarios related to HIV prevention attitudes and behaviours and perceived norms about salient social reference groups will be discussed. Aim 2: Based on results from Aim 1, survey questions using different ways of assessing norms will be developed to assess perceived social norms around HIV-related prevention behaviours and attitudes among different reference groups. Aim 3: Through cognitive interviews, the content validity of these survey questions to elicit perceptions of social norms about HIV-related attitudes and behaviours among specific social reference groups will improve.
USA 2021-11-11 2024-11-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
SIMON EWASU -
ID:
EXPLORING THE INFLUENCE OF SCHOOL LEADERSHIP ON STUDENTS’ ACADEMIC PERFORMANCE: A COMPARATIVE STUDY OF TWO PRIMARY SCHOOLS’ IN OMODOI SUB-COUNTY-UGANDA
REFNo: SS980ES

1. To explore how school leadership influences learners’ academic performance in schools’?
2. What school leaders do to improve on the students’ academic performance in schools
3. To find out the teachers’ and students’ perceptions on the school leadership on students’ academic performance.
4. To find out the strategies school leaders employ to support their own teams to improve on the learner’s academic performance?

 Uganda 2021-11-11 2024-11-11 Social Science and Humanities Non-Clinical Trial Degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
 Modular Wireless Patient Monitoring System (MWPMS) Among a Subset of Patients Enrolled in an Observational Study of Sepsis in Uganda
REFNo: HS1687ES

At the FPRRH study site in Uganda, investigators will incorporate an assessment of the utility of a novel Modular Wireless Patient Monitoring System (MWPMS), supported by personalized data analytics, to provide a continuous, objective measure of physiological status in patients with sepsis. We aim to demonstrate correlation with manually collected vital signs. We also aim to identify specific features or combinations of features measured via MWPMS that predict 28-day mortality. This is a sub-study which will be incorporated in the main protocol observing sepsis patients hospitalized in Uganda
 Uganda 2021-11-11 2024-11-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Owenda Omulo Charles
ID:
The socioeconomic impact of floriculture industry on the livelihoods of communities hosting flower farms in Uganda
REFNo: SS1004ES

Main Objective
The main aim of this study is to examine the socio-economic impact of flower farm projects on the livelihoods of their host communities.

Specific Objectives
Specifically, the study will have the following objectives and associated research questions;
To find out how the financial reward (wages) has contributed in changing the livelihood of flower farm workers from the time they joined the flower farm.

To examine the extent by which flower farms have contributed to the improvement of the basic infrastructure and producer goods needed to support people’s livelihoods in their host communities.
To find out how the farms are prepared to overcome the challenges of environmental degradation and human abuse (as witnessed in workers’ exposure to hazardous agrochemicals in other countries) in order to improve people’s livelihoods.

 Kenya 2021-11-11 2024-11-11 Social Science and Humanities Non-Clinical Trial Degree Award
Christine Watera
ID:
Cyclical Acquired HIV Drug Resistance Surveillance: Focusing on Dolutegravir in Uganda
REFNo: HS1774ES

a) To estimate the prevalence of acquired drug resistance (ADR) among individuals receiving DTG for at least 12 months with VL non suppression, by age sub-groups
• Adolescents and Adults ≥ 15 years
• Children < 15 years old
b) To describe the patterns of ADR among individuals receiving DTG for at least 12 months with VL non suppression, by age sub-groups
c) To describe the prevalence and pattern of ADR among individuals receiving DTG with VL non-suppression by sub-population characteristics (e.g., sex, duration on antiretroviral therapy (ART), line of ART, pregnant and breast feeding, etc.):
d) To compare the proportion of individuals with HIVDR pre- and post-intensive adherence counselling (IAC)

 Uganda 2021-11-11 2024-11-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Edith Birungi Mwebaze
ID:
Decision Making Dynamics in the use of Female Sterilisation by Women Living with HIV in Uganda
REFNo: SS1044ES

To explore the personal factors that influence the agency to implement decisions regarding use of sterilisation by women living with HIV in Uganda, To describe the micro-level social contexts that influence the decisions of Women Living with HIV on the sue of female sterilisation by as a method of contraception, To assess the macro- level cultural contexts that influence the decisions of Women Living with HIV to use sterilisation.
 Uganda 2021-11-11 2024-11-11 Social Science and Humanities Non-Clinical Trial Degree Award
Agata Staniewicz
ID: UNCST-2021-R012236
 Interspecific competition for acoustic space in birds
REFNo: NS302ES

Determine whether and how various species of birds compete with each other and with other animals for acoustic space.
 Poland 2021-11-11 2024-11-11 Natural Sciences Non-Clinical Trial Non-degree Award
Karlmax Rutaro
ID: UNCST-2021-R012720
 Value chain hygiene practices and microbial contamination of street and market vended ready-to-eat grasshoppers, Ruspolia spp. in Uganda
REFNo: HS1869ES

The overall aim of the study is to document the value chain hygiene practices and microbial contamination of street-hawked and market-vended RTE grasshoppers, Ruspolia spp. in Uganda.

The specific objectives are:
i. To document the hygiene practices along the RTE grasshopper value chain, including the personnel involved, in Kampala City and Masaka Town in Uganda.
ii. To determine the level of microbial contamination in the RTE grasshoppers at different stages of the value chain in Kampala City and Masaka Town in Uganda.
iii. To establish the relationship between RTE grasshopper value chain hygiene practices and the microbial contamination.

 Uganda 2021-11-11 2024-11-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Allen Namagembe Sekitoleko
ID: UNCST-2019-R000214
 Injecto Easyject contraceptive self-injection use in Uganda
REFNo: HS1851ES

1.To assess ease of use of the Easyject device, from the perspective of clients (self-administration) and providers (provider administration), relative to the Uniject
2.To identify challenging steps when learning to use the Easyject
3.To evaluate overall acceptability of Easyject injection device for clients, providers and stakeholders
 Uganda 2021-11-11 2024-11-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jane Namukobe
ID:
Bioactivity and chemical investigation of natural products composition from selected plants used in skin infections and protection.
REFNo: NS306ES


i. To determine the sun protection, antioxidant and antibacterial activities of extracts from selected plants used in skin infection and protection
ii. To determine the dermal and oral toxicity of extracts
iii. To isolate and elucidate the structures of bioactive compounds
iv. To determine the sun protection factor, antioxidant and antibacterial activities of isolated compounds
v. To prepare synthetic derivatives of some interesting isolated compounds

 Uganda 2021-11-11 2024-11-11 Natural Sciences Non-Clinical Trial Non-degree Award
Herbert Muyinda
ID: UNCST-2019-R000373
 A comparative study of COVID-19 tests in the DRC and Uganda: Situating the knowns and unknowns in the COVID-19 pandemic
REFNo: SS1088ES

To study the consequences of unknowing on people’s health-seeking behavior during the COVID-19 pandemic.,To examine COVID-19 testing as a technology of knowing, and the responses [to COVID-19 pandemic] made visible by testing,To explore how testing—and in particular the absence of testing—shapes both knowing and unknowing in the context of the pandemic. ,To explore how diagnostic tests have been used to devise and implement the COVID-19 response in both countries.,The general objective of this project is to provide an in-depth study of the role of diagnostic tests in relation to the management of COVID-19 pandemic in Uganda.,
 Uganda 2021-11-11 2024-11-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
Philip Leonard
ID:
Understanding the current challenges faced by coffee farmers in the Technoserve Farm College
REFNo: A162ES

1) Identify current concerns related to COVID-19.
2) Identify current challenges on farming activities including access to inputs, farms and markets.
3) Understand how coffee farmers are able to access to emergency finance.
4) Identify changes in availability of food.

 Canada 2021-11-11 2024-11-11 Agricultural Sciences Non-Clinical Trial Non-degree Award
Etheldreda Nakimuli-Mpungu
ID: UNCST-2020-R014808
 Promoting Adherence to Anti-retroviral Therapy and Viral suppression among HIV positive Young People in Uganda through Group Support Psychotherapy: Study Protocol for a Pilot Randomized Controlled Trial
REFNo: HS864ES

To pilot measures of cost-effectiveness,To explore whether or not psycho-social factors mediate or modify the effect of GSP on ART adherence and viral suppression among young people attending Kitgum Hospital HIV Clinic .,To assess the feasibility, acceptability and preliminary effectiveness of GSP in promoting ART adherence and viral suppression among young people attending Kitgum Hospital HIV Clinic,To use the qualitative data obtained to modify GSP to suit the needs of young people with HIV,To conduct community-based participatory qualitative research to obtain information on the potential usefulness of group support psychotherapy in improving ART adherence and viral suppression among young people attending Kitgum Hospital HIV Clinic,
 Uganda 2021-11-08 2024-11-08 Medical and Health Sciences Non-degree Award
Charles  Katulamu
ID:
Fertility Behaviors among recent university graduates in Kampala-Uganda.
REFNo: SS997ES

i. To establish relationship, union, and/or marriage patterns among recent university graduates.
ii. To investigate the fertility desires, preferences, and intentions among recent university graduates.
iii. To explore recent university graduates’ knowledge and experiences on contraceptive use and abortion.

Uganda 2021-11-05 2024-11-05 Social Science and Humanities Non-Clinical Trial Degree Award
Joaniter Nankabirwa Immaculate
ID: UNCST-2021-R012896
 Infant Malaria following IPTp with Artemisinin-based Combination Therapy (IMPACT)
REFNo: HS1819ES

To compare the incidence of malaria from 4 weeks to 1 year of age among children born to mothers randomized to receive intermittent preventative therapy in pregnancy (IPTp) with monthly sulfadoxine pyrimethamine (SP) alone, monthly DP alone, or both monthly SP+DP.

To determine whether infant sex modifies the association between maternal IPTp regimen and the incidence of malaria from 4 weeks to 1 year of age.

To compare innate and adaptive effector and regulatory responses among children born to mothers randomized to receive intermittent preventative therapy in pregnancy (IPTp) with monthly sulfadoxine pyrimethamine (SP) alone, monthly DP alone, or both monthly SP+DP.

Uganda 2021-11-05 2024-11-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Laban Musinguzi Kashaija
ID: UNCST-2020-R014407
 Midterm Review of the Higher Education Access Program
REFNo: SS1067ES

1. Assess the extent to which the expected short and intermediate outcomes of the program have been achieved;
2. Review program implementation effectiveness as well as draw interim lessons that can help optimize the Program’s impact going forward.
Uganda 2021-11-05 2024-11-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Velma  Kivali Majani
ID:
Microbial contamination at slaughter and retail points of the pork value chain in Uganda
REFNo: HS1820ES

1.To determine the prevalence and associated risk factors for non-typhoidal Salmonella infection among meat handlers in the pork value chain in selected cities in Uganda 2.To determine prevalence of non-typhoidal Salmonella in pig carcasses and pork at various points in the pork value chain and to evaluate risk factors associated with those prevalences in selected cities in Uganda 3.To determine the levels of contamination with coliforms in pig carcasses and pork at various points in the chain and evaluate risk factors associated with those levels in selected cities in Uganda 4.To characterize non-typhoidal Salmonella from swine, humans and the slaughter/retail environments in Uganda and determine the potential for pig to transmission.
Kenya 2021-11-03 2024-11-03 Medical and Health Sciences Non-Clinical Trial Degree Award
Irene  Nakatudde
ID:
Excessive weight gain and associated factors in HIV-infected adolescents on dolutegravir-based antiretroviral therapy in Kampala, Uganda
REFNo: HS1837ES

1. To determine the prevalence of excessive weight gain in HIV-infected adolescents on DTG-based ART attending KCCA health centres in Kampala.
2. To identify the factors associated with excessive weight gain in HIV-infected adolescents on DTG-based ART attending KCCA health centres in Kampala.

Uganda 2021-11-03 2024-11-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
 Secondary Research of MUWRP Sepsis Study Biospecimens: UNC 1 Evaluation of a Lateral Flow Immunoassay for Measuring Covid-19 Antibodies and 2 Related Inflammatory Biomarkers
REFNo: HS1821ES

The objective of the UNC study is to understand if the nonpowered lateral flow assay technology is as accurate as the powered GenScript SARS-CoV-2 surrogate virus neutralization test in detecting COVID-19 infection
 Uganda 2021-11-02 2024-11-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
James Kisambu
ID:
Uganda Prisons Service Project Evaluation Protocol
REFNo: HS1307ES

Objectives of UPS Program Evaluation
i. To evaluate the targeted HTC models to improve earlier identification of HIV-positive and negative individuals, and linkage of people living with HIV (PLHIV) in prisons community and facility sites and linkage and promotion of HIV prevention among HIV-negative individuals
ii. To evaluate innovative approaches that increase adherence, ART retention, and viral load (VL) suppression among adult and pediatric HIV clients.
iii. To determine if there is improved identification of TB-infected individuals, effective scale up of comprehensive TB/HIV services at individual sites, and progress towards reduction of TB burden among HIV/TB co-infected clients within the CDC-supported prison facilities
iv. To evaluate innovative PMTCT & HEI approaches that increase identification of HIV-positive and syphilis-infected pregnant & breastfeeding women (PBFW), enhance immediate ART uptake, adherence and retention, VL suppression and syphilis treatment among PBFW, reduce MTCT rates of HIV and syphilis and ensure documentation of 18 month final outcome status for all HEIs
v. To evaluate innovative interventions that are designed to improve data quality and data utilization for program evidence-based decision making at the facility level
vi. To determine if the strengthening of the existing laboratory network and its quality management systems increased the ART initiation and ART monitoring at the facility level.
vii. To determine the relationship between regional prison level performance reviews and human resource (HR) performance on facility performance including access, coverage, retention and loss to follow up.


 Uganda 2021-11-01 2024-11-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Emmanuel Sendaula
ID: UNCST-2020-R014767
 Isoniazid preventive and antiretroviral therapy-associated Pellagra: A case series of Reach Out Mbuya.
REFNo: HS1474ES

To describe the clinical manifestations of patients on Isoniazid preventive and antiretroviral therapy presenting with pellagra 2. To review the health outcomes of patients on Isoniazid preventive and antiretroviral therapy presenting with pellagra particularly as related to INH withdrawal
Uganda 2021-11-01 2024-11-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan Ifeagwu
ID:
The perceptions and values of multisectoral stakeholders related to universal health coverage (UHC) in Uganda
REFNo: HS1478ES

General objective:
To explore the perceptions, understanding and importance of achieving universal health coverage (UHC) by key stakeholders in Uganda.


Specific objectives:
a. To establish and enumerate the perceived importance being given to UHC as well as key barriers and challenges to achieving UHC in Uganda by national, regional and international health policymakers.
b. To understand local healthcare workers’ awareness and perceptions of UHC and examine differences between the views of urban and rural healthcare workers.
c. To determine the urgency, need, perceived impact (against the Sustainable Development Goals) placed on UHC by stakeholders, including policymakers and healthcare workers.
d. To use generated evidence to develop a policy brief using case examples highlighting promising approaches to support multisectoral UHC collaboration.

 Austria 2021-11-01 2024-11-01 Medical and Health Sciences Non-Clinical Trial Degree Award
Theopista Fokukora
ID:
IMPROVING ACCESS AND USE OF EMERGENCY CONTRACEPTION AMONG ADOLESCENTS IN THE TOORO SUB-REGION OF UGANDA
REFNo: HS1829ES

1. To assess the prevalence of EC use among adolescents in Tooro Sub-region, Uganda
2. To investigate the individual factors associated with ECs use among adolescents in Tooro Sub-region, Uganda.
3. To investigate the community-based socio-economic and cultural factors associated with EC use among adolescents in Tooro Sub-region, Uganda.
4. To assess the health system and service provider factors associated with the provision of ECs to adolescents in Tooro Sub-region, Uganda.
5. To determine the effect of a reproductive health education intervention on knowledge, attitude, and practices of providers as well as utilization of EC among adolescents.

Uganda 2021-11-01 2024-11-01 Medical and Health Sciences Non-Clinical Trial Degree Award
Paul Bangirana
ID:
Developing the Uganda National Mental Health Response to Disasters
REFNo: SS995ES

To design a national mental health response for disasters,To evaluate the cost effectiveness of implementing the intervention,To identify enabling factors for implementing the intervention in the relevant government ministries (acceptability),To identify barriers to implementation of the intervention in the community (feasibility),a)To develop a psychosocial intervention for victims, their families and health care workers during disasters,
 Uganda 2021-10-28 2024-10-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
Mary Acanit
ID:
Use of electronic library resources by postgraduate students in the Faculty of Engineering at Kyambogo University in Uganda
REFNo: SS948ES

To examine the use of electronic library resources by postgraduate students in the Faculty of Engineering at Kyambogo University in Uganda, with a view of suggesting a model to improve the use of those resources among engineering students.
 Uganda 2021-10-28 2024-10-28 Social Science and Humanities Non-Clinical Trial Degree Award
Namulema Edith
ID:
Effectiveness of the ‘LeVe CPAP’ against the standard AIRVO CPAP among Covid-19 patients with Acute Hypoxemic Respiratory Failure at Mengo Hospital Kampala Uganda: A Cross-Over Randomised Trial.
REFNo: HS1647ES

The main objective of the trial is to compare the clinical effectiveness of the LeVe CPAP device to the standard AIRVO CPAP in the delivery and maintaining continuous positive airway pressures among patients diagnosed with AHRF at Mengo Hospital Uganda.
 Uganda 2021-10-28 2024-10-28 Medical and Health Sciences Clinical Trial Non-degree Award
Thereza Piloya Were
ID: UNCST-2019-R000491
 Optimizing Performance of the Human Powered Nebulizer Prototype; Exploring stakeholder perceptions towards the human-powered nebulizer
REFNo: HS1433ES

We aim to explore the perceptions towards the human-powered nebulizer by the stakeholders (health care workers, village health teams and caregivers).
Uganda 2021-10-27 2024-10-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Paul Mukasa
ID: UNCST-2021-R013464
 Antirabies compounds in Selected Medicinal Plants used in the Treatment of Rabies in Uganda
REFNo: NS290ES

Mian objective: To explore the medicinal plants used in the treatment of rabies for bioactive potential and phytochemical compounds as possible leads to antirabies agents in Uganda. Specific objectives: 1. To carry out an ethnobotatical survey on plant species used to treat rabies in Uganda. 2. To determine the cytotoxicity of the crude extracts of the selected plants used to treat rabies. 3. To determine the antirabies potency of the crude extracts of selected plants against rabies virus. 4. To elucidate the structure of the antirabies compound(s) isolated from the most bioactive portion(s).
 Uganda 2021-10-27 2024-10-27 Natural Sciences Non-Clinical Trial Degree Award
Kenneth Odur
ID:
Youth Public Health Ambassadors Community Health Assessment 2021
REFNo: SS1025ES

Collect information on sanitation and hygiene, nutrition, health and safety, and preventive health services present at primary and secondary schools located in participating communities surrounding Lira, Uganda.,Collect information on existing health care services and infrastructure present at health facilities in participating communities surrounding Lira, Uganda.,Collect data on health behaviors, knowledge and attitudes among adolescents living in participating communities surrounding Lira, Uganda.,Collect demographic information, baseline knowledge and beliefs about disease, and health-related behaviors from households in participating communities surrounding Lira, Uganda,To Asses a comprehensive Community health behaviours and practices in the Rural comminities in Lira District Northern Uganda. ,
 Uganda 2021-10-27 2024-10-27 Social Science and Humanities Non-Clinical Trial Non-degree Award
Peter Olds
ID: UNCST-2023-R006240
 The impact of the COVID-19 pandemic on NCD care in Mbarara, Uganda
REFNo: HS1535ES

1. Patients differentially sought medical care during the COVID-19 pandemic, resulting in different utilization of NCD care at health centers and a regional referral hospital.
2. We hope to understand both patient and provider perspectives on NCD care during COVID-19 pandemic, and discuss their outlook on more mobile versions of care.
 USA 2021-10-26 2024-10-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Urs KALBITZER
ID:
Aerial Imagery Data for the Construction of Primate Nutritional Landscapes
REFNo: NS303ES

To develop a methodological framework and create high-resolution models of the temporal and spatial distribution of nutrients for primates and other animals, so called ‘nutritional landscapes’
 Germany 2021-10-26 2024-10-26 Natural Sciences Non-Clinical Trial Non-degree Award
Kenia Martinez Raquel
ID:
PREVALENCE AND FACTORS ASSOCIATED WITH PRIMARY POSTPARTUM HEMORRHAGE AMONG WOMEN WITH PRE-ECLAMPSIA/ ECLAMPSIA DELIVERING AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS1564ES

General Objective
To determine the prevalence and factors associated with primary postpartum hemorrhage among women with pre-eclampsia/eclampsia delivering at Mbarara Regional Referral Hospital

Specific Objectives
1. To determine the prevalence of primary postpartum hemorrhage in women with pre-eclampsia/ eclampsia at Mbarara Regional Referral Hospital.

2. To determine the factors associated with primary postpartum hemorrhage in women with pre-eclampsia/ eclampsia at Mbarara Regional Referral Hospital.

 Eswatini 2021-10-25 2024-10-25 Medical and Health Sciences Non-Clinical Trial Degree Award
Julian Adong
ID: UNCST-2021-R013487
 A social media intervention to promote antiretroviral therapy adherence among adolescents and young adults living with HIV in Uganda
REFNo: HS1824ES

Determine the feasibility, acceptability, and preliminary effectiveness of the U-SMART intervention among AYAWH in Uganda.,Adapt the social media to improve ART outcomes (SMART) Connections platform to create Uganda-SMART (U-SMART), a novel WhatsApp-based social media intervention to improve antiretroviral therapy (ART) adherence among adolescents and young adults with HIV (AYAWH) in Uganda.,
 Uganda 2021-10-25 2024-10-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Frank Mwiine Norbert
ID:
Epidemiological investigation of brucellosis in livestock in selected agro-pastoralist districts of Eastern Uganda
REFNo: A153ES

1. To determine the sero-prevalence of brucellosis in various livestock raised under the agro-pastoralist system in Eastern Uganda.
2. To establish the status and the factors behind the dynamics and perpetuation of livestock brucellosis in selected districts of Eastern Uganda.
3. To determine knowledge, attitudes and practices (KAPs) vital for brucellosis control among livestock farmers in the agro-pastoralist system in Eastern Uganda.
4. To isolate and molecularly characterize causative bacterial agents of brucellosis infecting livestock in Eastern Uganda.
5. To determine and raise awareness, biosecurity and biosafety on brucellosis and work with stakeholders to participatorily develop sustainable disease reduction protocols.

 Uganda 2021-10-25 2024-10-25 Agricultural Sciences Non-Clinical Trial Non-degree Award
Brenda Nakimuli Luswata
ID: UNCST-2021-R013228
 Refining the programme theory for realist inquiry on adolescent SRH accountability in disadvantaged urban areas: macro and meso-contextual drivers and social mechanisms. Case studies Uganda and Benin
REFNo: SS1032ES

(4) To develop guidance on accountability for adolescent girls living in urban slums and methodological guidance for realist evaluation of complex problems. (Work package 4),To develop an overarching programme theory (Work package 3),To test and refine the initial programme theory grounded in case studies conducted in two urban poor neighborhoods in Delhi and Mumbai, India ; Kampala, Uganda and Cotonou, Benin (Work package 2),To develop the initial programme theory on accountability towards adolescent girls living in urban slum, based on the MRT and existing imperical literature on accountability in sexual and reproductive health in an urban and rural health system (Van Belle, 2014, Van Belle & Mayhew, 2016; Van Belle et al. 2018),To contribute to a better understanding of the causal chain underlying accountability in sexual and reproductive health towards adolescents living in urban slums in LMIC. The,
 Uganda 2021-10-25 2024-10-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
Joseph Erume
ID:
Antimicrobial resistance in zoonotic pathogens – a challenge for urban small holder livestock production system
REFNo: A156ES

1. To determine the burden of campylobacter infections in small holder, commercial broiler farms and food markets in and around Kampala, Uganda.
2. To determine management and risk factors which underlie the dynamics and perpetuation of in small holder, commercial broiler farms and food markets in and around Kampala, Uganda.
3. To establish the poultry farmers and traders’ knowledge, attitudes and practices related to AMR campylobacter strains and antibiotic usage at poultry farms.
4. To establish the AMR of campylobacters strains from the poultry phenotypically and molecularly including whole genome sequencing (WGS).

 Uganda 2021-10-25 2024-10-25 Agricultural Sciences Non-Clinical Trial Non-degree Award
Steven Odongo
ID: UNCST-2021-R013336
 DEVELOPMENT AND VALIDATION OF MULTIPLEXED LATERAL FLOW ASSAY FOR DETECTION AND DIFFERENTIATION OF SARS COV-2 FROM OTHER HUMAN CORONAVIRUSES
REFNo: HS1706ES

(1) Track levels of conservation of SARS CoV-2 structural proteins based on nucleotide sequences published in the Global Initiative on Sharing All Influenza Data (GISAID) database by sequencing laboratories in Uganda, (2) Identification and production of specific but conserved SARS-CoV-2 marker protein (s) capable of distinguishing SARS-CoV-2 from other hCoVs, (3) Develop a Nanobody (Nb) based multiplex LFA device targeting the marker proteins, and (4) Validate the performance characteristics of the LFA in a laboratory setting on archived sera.
 Uganda 2021-10-22 2024-10-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mark Jordans
ID: UNCST-2020-R014861
 Evaluating the effectiveness of Can’t Wait to Learn in formal education in Uganda
REFNo: SS1024ES

1)To assess the feasibility of the intervention and study (cRCT) methods, 2)To evaluate the effectiveness of CWTL in improving reading and numeracy outcomes of children in Primary 3 (P3), 3)To assess the value for money of CWTL and other factors for EdTech programme scale-up.
Netherlands 2021-10-22 2024-10-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Juliet Nattabi Kigongo
ID:
Vanishing Glaciers of the Rwenzori Mountains National Park (Uganda)
REFNo: NS291ES

Vanishing Glaciers project aims for the first
time to explore the streams of mountain
biogeochemistry, and the living
microorganisms of these remote
ecosystems, now strongly impacted by
climate change.
The project’s main goals are:
• To establish the census of microbial
life of the world’s glacier-fed
streams.
• To predict the future changes of the
glacier-fed streams biogeochemistry
as the world’s glaciers recede

1. Study the microbial life from glacier-fed streams
2.Study the biogeochemistry of glacier-fed streams
3.Study the environment of glacier-fed streams, including glaciological parameters
 Uganda 2021-10-22 2024-10-22 Natural Sciences Non-Clinical Trial Non-degree Award
Andrew Katumba
ID:
Performance of a novel, rapid AI-driven screening tool for improved COVID-19 patient care and management in Uganda
REFNo: SIR74ES

General Objective
To develop and deploy AI-driven screening tools for improved care and management of COVID-19 patients. This will be achieved through the following specific objectives:
Specific Objectives
1. To collect, curate and label Lung Ultrasound (LUS) images from COVID-19 patients and patients with related pulmonary pathologies such as non-COVID-19 derived pneumonia, yielding a generalizable and representative image/video dataset.
2. To develop robust image-driven machine learning (ML) models for detection and screening of COVID-19 using the data from objective 1.
3. To build mobile and web-based applications that integrate the ML models, for online (real-time) and offline COVID-19 screening.
4. To pilot the developed applications and evaluate their clinical efficacy in COVID-19 screening.

Uganda 2021-10-22 2024-10-22 Engineering and Technology Non-Clinical Trial Non-degree Award
Moffat  Nyirenda Joha
ID: UNCST-2020-R019333
 Identification and characterization of Diabetes in low-resource Populations
REFNo: HS1791ES

The secondary study objectives are:
1. To establish a base-line cohort of well-characterised people with diabetes to understand disease progression of the different phenotypes, including uptake and response to treatment.
2. To identify and recruit a cohort of non-diabetic volunteers (including prediabetes i.e., at high risk of developing diabetes) for longitudinal follow-up.
i. To identify a cohort of non-diabetic people in order to measure the incidence of disease in the future estimate incidence of diabetes.
ii. To assess the burden and rates of progression of vascular complications associated with the different phenotypes of dysglycaemia.
Malawi 2021-10-22 2024-10-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Frederick Mubiru Edward
ID:
Market Research on User Perspectives for a 4-month Depot Medroxyprogesterone Acetate Subcutaneous (DMPA-SC) Product
REFNo: HS1792ES

1. To solicit input from potential and current contraceptive injectable users, as well as males/partners, on acceptability and implications for having multiple injectable products of different durations in the market, with an emphasis on a 4-month DMPA-SC product as well as a potential 6-month injectable
2. To co-create marketing strategies/messages with current and potential users for the introduction and differentiation of new injectable products

 Uganda 2021-10-22 2024-10-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Josef Bryja
ID:
Evolutionary diversity of small mammals in isolated mountains in north-eastern Uganda - stepping stones for colonization of the Albertine Rift and Kenyan Highlands from Ethiopia?
REFNo: NS301ES

Overall goal: To analyse genetic diversity of small mammals and their pathogens to test alternative hypotheses of colonization of Eastern Afromontane Biodiversity Hotspot (EAMBH)
Objective: Description of biodiversity patterns in EAMBH using integrative approach

Output 1: List of small mammals of isolated sky islands of north-eastern Uganda
Activity 1: Field sampling, species identification (using integrative approach)

Output 2: Phylogeographic scenarios for the colonization of EAMBH, identification of "refugia within refugia", biogeographical regionalization
Activity 2: Combination of obtained (genetic) data with other datasets from Ethiopia, Kenya, Tanzania, etc. Testing of phylogeographic hypotheses.

 Czech Republic 2021-10-22 2024-10-22 Natural Sciences Non-Clinical Trial Non-degree Award
Eddy Walakira Joshua
ID: UNCST-2022-R009077
 Strengthening the Effectiveness of National Children’s Care Systems: A Political Analysis of Uganda
REFNo: SS1064ES

This study will examine the effectiveness of the National Children’s Care System in Uganda focusing on the political, bureaucratic and economic forces as well as the strategies that augment the effectiveness of this system.

The study aims to use the collected data to develop an adaptable framework to achieve effective national care systems for children in Low-Income Countries (LICs).

In specific terms, the research will:
1. Examine the political, bureaucratic and economic forces shaping the effectiveness of Uganda’s national children’s care systems

2. Delineate the strategies to improve the capacity of these systems to protect children

3. Develop an adaptable framework for Uganda to analyze factors shaping children’s care systems in LICs?
 Uganda 2021-10-22 2024-10-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Gorretti Nassali
ID:
Trends of Breast Cancer among patients younger than 40 years at St. Francis Hospital Nsambya: A cross section descriptive study
REFNo: HS1758ES

This study aims to describe prevalence by age, stage at diagnosis, cancer type and grade, and hormone receptor status, among women younger than 40 years at St. Francis Hospital Nsambya between 2010 and 2020.
 Uganda 2021-10-21 2024-10-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Anna Ritah  Namuganga
ID:
Mycobacterium tuberculosis associated immune activation and exhaustion profiles for prediction of active pulmonary tuberculosis
REFNo: HS1201ES

Main Objectives
Determine the differential expression of immune activation and exhaustion markers to predict active TB disease among presumptive TB cases.
Primary Specific Objectives
i. To determine the levels of soluble markers of immune activation and exhaustion in serum of active PTB cases, LTBI and those with ORDs and response to treatment.
ii. To determine levels of immune activation and exhaustion associated cytokines/chemokines in serum among active PTB, LTBI and ORDs and response to treatment.
iii. Perform a phenotypic profiling of expression of markers immune activation and exhaustion in PBMCs and determine their association with active PTB, LTBI states or other respiratory diseases (ORDs).
iv. To determine the activation and exhaustion genes expression profiles in QFT Gold plus cell pellets and compare levels in active PTB cases and LTBI.

 Uganda 2021-10-20 2024-10-20 Medical and Health Sciences Degree Award
Andrew Okwi Livex
ID: UNCST-2021-R013180
 Unlocking the potential of thiocyanate in cassava root for management of painful crisis in sickle cell disease patients in Uganda
REFNo: HS1486ES

1. To determine the frequency of cassava consumption in the districts of Uganda with high prevalence of sickle cell disease
2. To assess the frequency of painful crisis among SCD patients in these districts.
3. To determine the levels of thiocyanate in patients with SCD in these districts
4. To determine the optimum concentration of thiocyanate that causes antisickling (in vitro studies)

 Uganda 2021-10-20 2024-10-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Khamisi Musanje
ID: UNCST-2021-R012863
 Acceptability, Feasibility and Effectiveness of a Mindfulness based Intervention to Promote Adherence to Antiretroviral Therapy among Adolescents in Kampala.
REFNo: HS1656ES

1. To adapt and explore acceptability of ACT-DNA-v among users (ALWHA) and providers (HCPs).
2. To measure feasibility of the adapted ACT-DNA-v for use with ALWHA.
3. To examine the impact of ACT-DNA-v on reducing proximal psychosocial barriers to medication adherence (depression, anxiety and stigma) among ALWHA.
4. To measure effectiveness of a mindfulness based intervention (ACT-DNA-v) on self-reported adherence among ALWHA in Kampala, and ascertain its impact on viral load reduction via analysis of data from medical records

Uganda 2021-10-20 2024-10-20 Medical and Health Sciences Clinical Trial Degree Award
Damalie Nalwanga
ID: UNCST-2021-R013217
 SEVERE PNEUMONIA IN CHILDREN: THE ABILITY OF BODY COMPOSITION TO PREDICT SURVIVAL, AND THE EFFECT OF NUTRITIONAL SUPPLEMENTATION ON OUTCOMES
REFNo: HS1719ES

4. To determine the effect of a nutritional intervention (RUTF) on clinical outcomes (post discharge mortality, re-admission, and occurrence of severe acute malnutrition) of children hospitalized for severe pneumonia.,3. To determine the effect of a nutritional intervention (RUTF) on fat and muscle mass in children hospitalised for severe pneumonia.,2. To compare the ability of various muscle and fat mass indices to predict survival in children hospitalised for severe pneumonia.,1. To describe the role of nutritional status on outcomes following hospitalization for severe pneumonia among children.,To describe the relationship between muscle and fat mass and survival, and determine the role of nutritional supplementation on fat and muscle mass, and on treatment outcomes of children hospitalized for severe pneumonia,
 Uganda 2021-10-20 2024-10-20 Medical and Health Sciences Clinical Trial Degree Award
Miriam Nakalembe
ID: UNCST-2021-R014040
 A Public Health Approach to Cervical Cancer Prevention in Uganda
REFNo: HS1727ES

Aim 1. To evaluate the uptake of, acceptability regarding and factors explaining non-participation in a community-based cervical cancer screening program.

Aim 2. To evaluate the uptake of, acceptability regarding and factors explaining non-participation in a community-based HPV vaccination program.

Uganda 2021-10-20 2024-10-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan Adakun
ID:
Comparing adherence to MDR-TB treatment among patients on self-administered therapy and those on Directly Observed Therapy: Non Inferiority Randomized Controlled Trial
REFNo: HS1796ES

Primary Objectives
1. To determine if adherence to MDR-TB treatment among patients on self-administered therapy (measured by Medication Events Monitoring System (MEMS) technology) is non-inferior to that among patients on Directly Observed Therapy (DOT)
Secondary objectives

1. To determine the correlation between serum MDR-TB drug concentrations and adherence as measured by MEMS technology


2. To compare treatment outcomes between MDR-TB patients on self-administered therapy and DOT

 Uganda 2021-10-20 2024-10-20 Medical and Health Sciences Clinical Trial Non-degree Award
Winfred Naamara
ID:
Understanding social support for family caregivers of patients with schizophrenia in greater Kampala metropolitan area, Uganda
REFNo: SS1038ES

The overall objective of this study is to examine how family caregivers of patients with schizophrenia generate and experience social support in greater Kampala metropolitan area.
Uganda 2021-10-19 2024-10-19 Social Science and Humanities Non-Clinical Trial Degree Award
Sandra Lamwaka
ID:
TOWARDS A NEWS INDUSTRY FRAMEWORK FOR TACKLING THE VICE OF BROWN ENVELOPE JOURNALISM: PERCEPTIONS OF JOURNALISTS AND PUBLIC RELATIONS PRACTITIONERS IN UGANDA
REFNo: SS1014ES

1. To examine journalists and PR practitioners’ perception of the brown envelope. 2. To identify the various forms that BEJ takes in Uganda. 3. To find out journalists and PR practitioners' perceptions on why BEJ is prevalent and enduring in Uganda. 4. To find out journalists and PR practitioner's perspectives on the policies that the media industry can employ to address the practice of BEJ in Uganda.
Uganda 2021-10-19 2024-10-19 Social Science and Humanities Non-Clinical Trial Degree Award
JANISCH Judith Judith
ID:
Ecological influences on Locomotor Performance in Free-Ranging Primates: a phylogenetic investigation
REFNo: NS299ES

- to investigate the evolution of arboreal locomotion in primates and discern which aspects of the arboreal environment most directly influence their locomotor performance.
- to describe kinematics of different primate species (Cercopithecus mitis, Cercopithecus ascanius, Cercopithecus lhoesti, Chlorocebus aethiops,
Lophocebus albigena, Papio anubis, Colobus guereza and Piliocolobus badius) in
their natural habitat and analyze the variation in a phylogenetic context.

 Austria 2021-10-19 2024-10-19 Natural Sciences Non-Clinical Trial Non-degree Award
Sheila Balinda Nina
ID: UNCST-2021-R013804
 Exploration of the Virologic Characteristics of Recently Transmitted HIV-1 Viruses in Uganda and Kenya
REFNo: HS1635ES

1. To identify key unique molecular features of T/F virus strains and characterize them
2. To relate these unique genetic features to viral protein structures and in vitro virus phenotypes.
3. To determine the difference between HIV-1 co-receptor usage of the T/F virus variants and NT virus strains.
4. To determine particle infectivity of T/F virus strains in comparison to that of the NT virus strains.
5. To compare the resistance of T/F virus strains to the antiviral effects of type I interferons to that of the NT strains
6. To determine the sensitivity of T/F virus strains to broadly neutralizing antibodies in comparison to the non-transmitted virus strains.
 Uganda 2021-10-15 2024-10-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Noah Kalengo
ID:
LIVED EXPERIENCES OF UNCIRCUMCISED POKOT WOMEN IN AMUDAT DISTRICT
REFNo: SS1046ES

To explore the characteristics of uncircumcised Pokot women in Amudat District.

To explore the psychosocial experiences of uncircumcised Pokot women in Amudat District.

To analyze the protective factors/coping resources among the uncircumcised Pokot women that enable them to survive despite their experiences.

 Uganda 2021-10-15 2024-10-15 Social Science and Humanities Non-Clinical Trial Degree Award
Joseph  Matovu KB
ID: UNCST-2020-R014654
 Feasibility and acceptability of integrating PrEP and safer conception messaging into assisted partner notification
REFNo: HS1625ES

To examine the feasibility and acceptability of integrating gain-framed vs. loss-framed messages on PrEP and safer conception into the assisted partner notification (APN) program in Uganda
 Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
 Smart Triage + QI: A digital triaging platform to improve quality of care for critically ill children
REFNo: HS1745ES

To identify and examine opportunities for ongoing improvement to strengthen the health system. ,To enable healthcare workers to recognize the most urgent children more rapidly and allocate existing resources more efficiently,To implement Smart Triage + QI to improve the quality of care at three UCMB health care facilities and Gulu Regional Referral Hospital (a government facility). ,
 Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eleanor Namusoke Magongo
ID: UNCST-2021-R013199
 Uganda Paediatric and Adolescent HIV Cohort on Antiretroviral Therapy: Study Protocol (UP-ART)
REFNo: HS1699ES

The objectives of this study are to:
1) Describe the characteristics of children and adolescents living with HIV receiving paediatric care in the participating centres and coverage of ART
2) Describe the uptake of new antiretroviral drugs such as DTG across age groups and regions
3) Assess the effectiveness and safety of new antiretroviral drugs such as DTG, including viral suppression, incidence of adverse events, serious adverse events and discontinuation of drug
4) Assess broader clinical outcomes including retention in care, mortality, disease progression, immune response, viral suppression, overall and by age and treatment regimen/treatment history
5) Assess (i) the prevalence of HIV drug resistance among children/adolescents start of treatment and the impact on treatment response, and (ii) among those who experiencing virological failure on DTG to describe the risk of accumulation of drug resistance (see sub-study Section 4).

Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 Integration of phone-based data capture tool to support real-time reporting and quality assurance of SARS-CoV-2 Ag RDT in Uganda
REFNo: HS1723ES

1. To pilot the integration of phone-based data collection tool and real-time reporting via a dashboard
2. To monitor quality and post-market surveillance of the Ag RDT in Uganda
3. To demonstrate the use of remnant Ag RDT samples in the routine surveillance of SARS –CoV-2 variants in Uganda
 Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Miriam Nakalembe
ID: UNCST-2021-R014040
 Use of mobile Text Messaging Service information for mothers in situations of limited access to physical antenatal and postnatal services during the COVID-19 Pandemic
REFNo: HS1732ES

1. To elicit requirements for incorporating maternal and child health educative messages into the developed mobile-based transport technology for mothers.
2. To incorporate maternal and child health educative messages into the developed mobile-based transport technology for mothers.
3. To evaluate the usefulness of the information to the mothers through the mobile Text Messaging Service.

Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ivan Segawa
ID: UNCST-2021-R012795
 Nurse-led PrEP Delivery for Young Women Attending Family Planning Clinics in Uganda
REFNo: HS1740ES

Aim 1: To evaluate the feasibility and acceptability of nurse-led PrEP delivery to adolescent girls and young women attending a family planning clinic in Uganda.

Aim 2: To assess PrEP persistence among adolescent girls and young women receiving nurse-delivered PrEP at a family planning clinic.

Aim 3: To compare the characteristics of adolescent girls and young women who accept with those who decline PrEP and those who persist with those who discontinue PrEP at a family planning clinic in Uganda.
 Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nixon Niyonzima
ID: UNCST-2020-R014577
 Utility of a Liquid Blood Biopsy for Non-invasive Lung Cancer Diagnosis and Biomarker Testing at Uganda Cancer Institute.
REFNo: HS1743ES

1. To compare ctDNA sequencing to standard histopathologic diagnoses of lung cancer in patients with advanced stage lung cancer at the Uganda Cancer Institute (UCI).

2. To describe the tumor-specific molecular alterations present in lung cancer specimens and ctDNA in advanced stage lung cancer patients at UCI.
 Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ouma Simple
ID: UNCST-2021-R012820
 Childhood victimization and mental disorders among adolescents of sex-working and non-sex working mothers in post-conflict Gulu city in Northern Uganda - a cross-sectional study
REFNo: HS1769ES

The main goal of this study is to provide the evidence needed by the health care programmers and policymakers to inform appropriate policies and practices on prevention, screening, and management of victimizations among adolescents in Uganda. Specifically, the following are the study objectives:
1. To determine the prevalence of childhood victimization among adolescents.
2. To examine the relationship between sociodemographic characteristics and general health and childhood victimization among adolescents.
3. To examine the relationship between maternal sex work status and childhood victimization.
4. To examine the relationship between maternal major depression and childhood victimization among adolescents.
5. To determine the prevalence of selected childhood mental disorders among adolescents.
6. To examine the relationship between exposure to childhood victimization and childhood mental disorders in post-conflict Gulu City.

Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Degree Award
Achilles Katamba
ID: UNCST-2019-R000540
 Interrupting HIV and TB Stigma in the Household during TB Contact Investigation in Uganda
REFNo: HS1788ES

This project aims to evaluate the effects of a complex intervention on household HIV stigma and uptake of HIV testing among household members undergoing TB contact investigation.
Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jonathan Izudi
ID: UNCST-2019-R000469
 Evaluating the impact of the COVID-19 pandemic restrictions on HIV care in Kampala, Uganda: a propensity-score matched and difference-in-differences analysis
REFNo: HS1709ES

Primary objective: To evaluate the impact of the COVID-19 pandemic restrictions on linkage to care, time to linkage, timely ART initiation, retention in care, viral load suppression, and mortality among people living with Human Immunodeficiency Virus (PLHIV) in the Kampala Capital City Authority (KCCA) health facilities in central Uganda

Secondary objective: To document and synthesize measures for continuity of service delivery for PLHIV during the COVID-19 pandemic
 Uganda 2021-10-12 2024-10-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Betty  Nambuusi Bukenya
ID:
Youth Wellbeing Champions: Piloting community-based, youth peer-led mental health and wellbeing support for young people in Uganda
REFNo: SS956ES

Study goal: To generate evidence around the effectiveness of a pilot community-based and responsive wellbeing / mental health intervention led by young people with lived experience of care and supported by social work practice/practitioners in Uganda. Specific objectives 1. Assess the level of knowledge and understanding of a trauma-informed approach to addressing mental health needs among social workers based on the Kirk Patrick pre-post questionnaire. 2. Assess the prevalence of clinical mental health, well-being, self-esteem/ self-worth, and depression symptoms among children and youth based on the WHO-5 / PHQ-9 and Rotter’s Locus of Control. 3. Examine the level of knowledge of mental health literacy, resilience, psychosocial support, and wellbeing practice among care leavers based on Kirk Patrick's pre-and post-assessments questionnaire.
Uganda 2021-10-12 2024-10-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Fred Ssewamala
ID: UNCST-2020-R014060
 Youth Health SMS: Using mobile technology to prevent HIV and related Youth Health problems: Sexual health, Mental health, and Substance use in southwest Uganda
REFNo: SS969ES

This study will result in the development of one of the first mobile phone-based interventions for Adolescents and Young Adults (AYA) in East Africa that begins to address the co-morbid HIV risk factors of sexual health, mental health, and alcohol use. AYA is a developmental period associated with the increased importance of peers, increased technology use, increased mobility, initiation of sex, emergence of mental health disorders (if at risk), and initiation of alcohol use. Consequently, AYA is a critical time for preventive interventions. Poor mental health and alcohol abuse are associated with increased risk for HIV infection. Thus, the proposed research will attempt to address these areas concurrently.

The proposed research will evaluate if adapting and updating the existing free and nationally available text message and interactive voice recognition (IVR) service included in *161 that was initially developed by FHI 360. Our work will test and tailor messages for AYA to disseminate pre-exposure prophylaxis (PrEP) information and pilot specific mental health and hazardous alcohol use screens. Symptomatic AYA will be referred to behavioral health counselors for further assessment and treatment as needed. AYA today rely heavily on mobile phones for information and services, thus we believe the proposed intervention could be applied and adapted across the region, and potentially in other under-resourced settings.

We will conduct formative research to evaluate and adapt an existing text-message and interactive voice recognition (IVR) platform. We will then pilot the new menus and examine if using this platform promotes HIV prevention (pre-exposure prophylaxis (PrEP), HIV testing, safer sexual behaviors) and increases mental health and alcohol use screening and linkage to counselors as needed for adolescents and young adults (AYA) in a rural Ugandan region with high HIV seroprevalence and limited resources.

2. State the study objective(s) and research question(s)
Aim 1: To adapt an evidence-based mobile phone-delivered sexual health program, to include PrEP information and deliver mental health and alcohol use assessments with the goal of increasing screening and referral, as well as linkage to counselors for AYA at HIV risk.

Aim 2: Evaluate through a pilot RCT (N=126 AYA, 15-19 years) intervention (a) acceptability and feasibility, and (b) impact on uptake of HIV prevention strategies, as well as screening and linkage to mental health and alcohol use school-based counselors.

 Uganda 2021-10-12 2024-10-12 Social Science and Humanities Clinical Trial Non-degree Award
Adeodata Rukyalekere Kekitiinwa
ID: UNCST-2019-R000799
 Mortality Surveillance Activity Protocol All-cause Mortality Surveillance in Bunyangabu, Kabarole and Kyenjojo districts, Uganda
REFNo: HS1755ES

the objective of establishing a mortality surveillance system is to enumerate and document all-cause mortality in the 3 districts of Bunyangabu, Kabarole, and Kyenjojo in Uganda. Specifically this will; a) determine HIV/AIDS related and proportionate mortality rate in the three districts, b) determine maternal and neonatal mortality rates in the three districts c) identify causes of death among HIV patients and causes of pregnancy-related deaths in the three districts and d) document the implementation process of mortality surveillance in order to inform future scale up.
 Uganda 2021-10-12 2024-10-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Waruiru Kolff Kayla Tinie
ID: UNCST-2021-R012291
 Turn-taking interactions in Eastern male Chimpanzees (Pan troglodytes schweinfurthii)
REFNo: NS295ES

Understanding the turn-taking systems of chimpanzees and how this relates to human language and it's origins. Hence, whether the turn-taking systems of chimpanzees are influenced by interpersonal contexts (social bonds & dominance rank).
 Netherlands 2021-10-12 2024-10-12 Natural Sciences Non-Clinical Trial Degree Award
ALEX NDYABAKIRA
ID:
Assessing use of SolarSack for treatment of safe drinking water in Uganda
REFNo: HS1680ES

1. To determine the willingness to buy and acceptability of SolarSack water treatment device
2. To determine the most appropriate cost per unit for SolarSack for rural, peri-urban and urban settings
3. To explore user preferences for the SolarSack device
4. To determine the effect of SolarSack use on prevalence of waterborne diseases

 Uganda 2021-10-11 2024-10-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Phyllis Kisa
ID: UNCST-2023-R007952
 SURGICAL NEONATES IN A LOW-RESOURCE SETTING: AN AUDIT OF NUTRITION AND OUTCOME
REFNo: HS1736ES

To audit our current the nutritional regime among newborns with gastro-intestinal anomalies admitted to the Paediatric Surgical Unit at Mulago National Referral Hospital(MNRH).
Uganda 2021-10-11 2024-10-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Tukwasiibwe Moses
ID:
Impact of forced displacement on labour markets in Uganda
REFNo: SS1039ES

Objective 1) Provide strong empirical evidence of the direct and indirect impacts. Against the backcloth of a comprehensive literature survey, and investigating non-camp urban refugee populations in Kampala and as well as camp based refugees in Nakivale refugee settlement in Uganda.

Objective 2) Identify the mechanism(s?) through which impacts occur. Analyzing the empirical evidence we will: i) explore direct and indirect (partial equilibrium) impacts and outcomes on the dynamics of labor market and business behavior, assessing impact-attribution and correlating variables such as labor supply and wages, capital investment/ labor trade-offs and demand side factors, productivity and skills, national and international investment patterns; ii) assess the role of political economy, regulatory and policy frameworks; iii) generate qualitative analysis of household and individual livelihood/life course experiences in relation to labor market outcomes, iv) generate local, national and comparative findings.

Objective 3) Support the development of evidence-based, effective, and context-specific jobs policy advice. The analytical outputs will provide a robust evidence base for jobs policy advice envisaged at different levels (local, national, and international), and for different stakeholders (e.g. municipal and national governments, donors, intergovernmental and non-governmental organizations, private sector investors, entrepreneurs and SME sector, and displaced and host populations). Policy advice will include, inter alia: finance and investment strategies, regulatory framework e.g. rights to work/rights at work and employer conditions for decent work), spatial planning, training and skills, role of investment incentives, socio-economic policies for displaced and host populations vis à vis labor markets.

Objective 4) Generate new data that will be in the public domain for use in further research. The proposed study will generate new statistical (survey) data sets for three of the four case countries: Colombia, Ethiopia and Uganda. In Jordan, the study team is already in possession of sufficient data through previous surveys conducted by Fafo and partners. When designing the new surveys, special attention will be given to establish robust baselines that can be applied in future impact analyses. Responding to this objective and the general TOR requirements, we shall place all the data generated in the proposed project in the public domain.

Uganda 2021-10-11 2024-10-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
PETER OMASWA
ID:
Relevance and Factors Affecting Exchange of Plant Material and Data to Conservation
REFNo: NS156ES

General Objective
To assess the importance of plant material and data exchange between African and European Institutions for conservation.

Specific Objectives
1. To review the extent to which plant material and data are exchanged between African and European institutions.

2. To evaluate the opportunities and constraints to plant material and plant data exchange between African and European Botanical Institutions.

3. To evaluate the proportion of exchanged plant material and data translated into conservation applications.


 Uganda 2021-10-08 2024-10-08 Natural Sciences Degree Award
Carolyn Nakisige
ID:
Preventing cervical cancer in HIV-infected Kenyan and Ugandan women
REFNo: HS1372ES

1. To evaluate HR-HPV DNA testing of self-collected vaginal swabs combined with VIA in screening for cervical cancer in HIV-infected women.
2. Determine if aflatoxin is a risk factor for cervical cancer among HIV-infected Kenyan and Ugandan women.
 Uganda 2021-10-08 2024-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Alice  Emasu
ID: UNCST-2021-R013920
 EXPERIENCES OF LIVING WITH OBSTETRIC FISTULA AMIDST COVID -19 PANDEMIC IN EAST AND CENTRAL UGANDA: Qualitative study.
REFNo: HS1464ES

General Objective
To document the experiences of living with fistula amidst the COVID-19 pandemic among women who developed OF during corona virus pandemic, those who had fistula and had started seeking for care, those who were repaired and were at the stage of reintegration and those declared as incurable between 15-49 years of age from Eastern and Central Uganda

Specific objectives

1) To document participant’s awareness about COVID 19 Pandemic

2) To explore the perceptions of women living with OF amidst COVID 19 Pandemic

3) To explore the effect of COVID -19 on the livelihood of women with OF.

4) To explore experience in accessing fistula services among women reintegrating and screened for surgeries during the COVID-19 pandemic.
 Uganda 2021-10-08 2024-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Scovia  Mbalinda Nalugo
ID: UNCST-2020-R014259
 Aging with HIV: Experiences and challenges of older adults 50 years and above living with HIV
REFNo: HS1759ES

3. To explore determine the challenges faced by older adults 50 years and above aging with HIV.,2. To describe the experiences of older adults 50 years and above aging with HIV.,The goal of this study is to explore the experiences, perceptions, and challenges of older adults 50 years and above aging with HIV.,
 Uganda 2021-10-08 2024-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Juma Kalyegira
ID:
The Role of Basic Psychological Needs Satisfaction for the Psychological Wellbeing and Social-Cultural integration of Refugees in Rhino Camp Refugee Settlement, Uganda
REFNo: SS905ES

• To estimate the relationship between the three psychological basic needs satisfaction (Autonomy, relatedness and competence) to the psychological wellbeing of refugees.
• To determine whether the basic psychological needs satisfaction influences refugee integration.
• To find out what factors influence the need satisfaction/frustration for refugees and how?
• To estimate whether physical and psychological need satisfaction interact in an “unprepared to benefit” or “buffering against adversity” direction?

Uganda 2021-10-08 2024-10-08 Social Science and Humanities Non-Clinical Trial Degree Award
John Byabagambi Bekiita
ID:
Ability and willingness to pay for voluntary medical male circumcision in Uganda: A mixed-methods study
REFNo: HS1523ES

1. To identify the factors that determine the ability to pay for VMMC in Uganda.
2. To determine the factors associated with willingness to pay for VMMC services in Uganda.
3. To find out the reasons that inform the choice of either the willingness to pay or not to pay for VMMC services in Uganda.

 Uganda 2021-10-08 2024-10-08 Medical and Health Sciences Non-Clinical Trial Degree Award
Julian Adong
ID: UNCST-2021-R013487
 Pandmic-related disruptions in HIV care among adolescents and young adults with HIV (AYAWHIV) and the potential for mHealth interventions.
REFNo: HS1686ES

To examine the effects of the COVID-19 restrictions on HIV treatment of AYALWHIV and assess the potential of mHealth intervention in bridging these disruptions.
 Uganda 2021-10-08 2024-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Fred Nalugoda
ID: UNCST-2021-R013343
 Transactional sex and HIV among men in Rakai, Uganda
REFNo: SS984ES

The overall goal of this research is to understand the characteristics of men who engage in transactional sex and the causal pathways that lead from transactional sex to incident HIV in Rakai, Uganda.
• Aim 1. To measure perceptions, content validity, and response processes of transactional sex measures in the Rakai Community Cohort Study
• Aim 2. To examine men’s experiences in transactional sex relationships and factors that may heighten risk for HIV

Uganda 2021-10-08 2024-10-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Dorothy Stamps Sarah
ID: UNCST-2019-R001036
 Dry Rifting in the Albertine-Rhino graben, Uganda (DRIAR)
REFNo: NS294ES

Investigating the physics of strain accommodation in the magma-poor Albertine- Rhino Graben of the East African Rift System using geodynamic modeling and GNSS geodesy
 USA 2021-10-08 2024-10-08 Natural Sciences Non-Clinical Trial Non-degree Award
Marsiale Kamugisha
ID:
'Analysing the Impact of Transformative Governance and Agroforestry on Household Food Security in Southwestern Uganda'
REFNo: A130ES

1)To assess contributory factors responsible for determining household transition to food security.
2)To evaluate the household governance system that enhances agroforestry-based food security.
3)To assess households’ potential benefits of agroforestry beyond food security.

Uganda 2021-10-06 2024-10-06 Agricultural Sciences Non-Clinical Trial Degree Award
Nadine Schubert
ID:
Genetically-based social communication in an inbred group-living wild mammal
REFNo: NS273ES

The aim is to investigate the role of immune genes of the major histocompatibility complex (MHC) in affecting odour cues used for social communication in banded mongooses. Furthermore, we want to investigate the link between MHC composition of an individual and fitness parameters as well as the impact of the MHC on microbiota communities. Last, it is crucial to test the ability of banded mongooses to discriminate MHC-based differences in odour cues in a natural setting.
 Germany 2021-10-05 2024-10-05 Natural Sciences Non-Clinical Trial Degree Award
Christine  Wiltshire Sekaggya
ID: UNCST-2019-R000578
 Clinical Predictors of 3-Months Isoniazid Rifapentine (3HP)- Related Adverse Drug Reactions (ADR) During Tuberculosis Preventive Therapy (PAnDoRA-3HP study)
REFNo: HS1582ES

Primary Objectives
1.To describe the safety profile of 3HP among people receiving tuberculosis preventive therapy.
2.To describe the effect of adverse drug reactions on tuberculosis preventive therapy completion rates
Secondary Objective
1.To describe the pharmacokinetic and pharmacogenomic determinants of ADRs among people receiving tuberculosis preventive therapy in Uganda
2.To determine the efficacy of 3HP when used for tuberculosis preventive therapy.

 Uganda 2021-10-04 2024-10-04 Medical and Health Sciences Clinical Trial Non-degree Award
Joseph Lutaakome
ID: UNCST-2020-R008323
 An International Multicenter, Randomized, Double-Blind, PlaceboControlled Trial of the Safety and Efficacy of Anti-Coronavirus Hyperimmune Intravenous Immunoglobulin for the Treatment of Adult Outpatients in Early Stages of COVID-19
REFNo: HS1715ES

Primary Objective
Primary objective: Among outpatients with recently diagnosed SARS-CoV-2 infection to compare the safety and efficacy of a single infusion of hIVIG (pooled for the 2 hIVIG

products) versus placebo, each given with SOC, on clinical status after seven days. Two hypotheses will be tested to address this primary objective, which compares the primary endpoint among two study populations: 1) participants where neutralizing MAb was not specified as part of SOC treatment (stratum 1, see Section 6.1 Overall Study Design); and 2) all randomized participants (stratum 1 and stratum 2 combined). hIVIG will be considered superior to placebo if either of the two hypotheses are rejected.
Secondary Objectives and Endpoints
Secondary objectives, including subgroup analyses and safety outcomes, will be addressed for all randomized participants and for those in stratum 1 and 2 separately.
Secondary Endpoints
The clinical status as classified on the ordinal outcome scale will be assessed with a number of additional analyses comparing hIVIG (pooled for the 2 hIVIG products) with placebo, among the overall study population as well as for the key subgroup of those not receiving anti-SARS-CoV-2 monoclonal antibodies as part of SOC (stratum 1), including:
1. All-cause hospitalization or death through 28 days.
2. All-cause mortality through 28 days.
3. Significant disease progression through 28 days, using a time to event analysis with outcome defined by fulfilling criteria for category 4 or 5 on the ordinal scale.
4. Distribution of ordinal scale outcome at Day 4, 14, and 28.
5. The proportion of participants with any disease progression at Day 7, using a sliding dichotomous scale progression defined by a categorization on the ordinal scale that is worse than the status at entry

 Uganda 2021-10-04 2024-10-04 Medical and Health Sciences Clinical Trial Non-degree Award
Joyce  Nankumbi
ID:
The status of OFSP production, utilization and the nutritional status and welfare of sweet potato growing households in northern and eastern Uganda
REFNo: A152ES

1. To characterise the consumption of vitamin A rich foods among households in the selected northern and eastern districts of Uganda 2. What is the food security status in the households in the selected northern and eastern districts in Uganda? 3. To document the production and consumption of orange-fleshed sweet potato among households in the selected northern and eastern districts in Uganda? 4. To identify infant feeding practices of women in the selected districts of northern and eastern regions in Uganda? 5. To identify water, hygiene and sanitation practices of households in the selected northern and eastern districts in Uganda 6. To establish the knowledge, attitudes and perception on the consumption of beta carotene-rich orange-fleshed sweet potatoes/ vitamin A-rich foods among households in the northern and eastern regions in Uganda,To determine status of orange-fleshed sweet potato production, utilization and the nutritional status and welfare of sweet potato growing households. in northern and eastern Uganda ,
 Uganda 2021-10-01 2024-10-01 Agricultural Sciences Non-Clinical Trial Non-degree Award
Arthur Nuwagaba
ID:
TOP MANAGEMENT TEAM CHARACTERISTICS AND PERFORMANCE OF UGANDAN STATE AGENCIES
REFNo: SS999ES

iv. Establish the joint effect of top management team characteristics, strategy implementation and external environment on the performance of Ugandan state agencies.,iii. Determine the moderating effect of the external environment on the relationship between top management team characteristics and the performance of Ugandan state agencies.,ii. Establish the mediating effect of strategy implementation on the relationship between top management team characteristics and performance of Ugandan state agencies.,i. Determine the influence of top management team characteristics on the performance of Ugandan state agencies.,The main objective of the study is to determine the influence of strategy implementation and external environment on the relationship between the TMT characteristics and the performance of state agencies in Uganda.,
 Uganda 2021-10-01 2024-10-01 Social Science and Humanities Non-Clinical Trial Degree Award
Wang Vibeke
ID:
Supporting Parenting Care Corners in Markets to Reduce Unpaid Care Work for the Vulnerable Business Women in Uganda
REFNo: SS944ES

1. To deepen the evidence base on whether and how reducing women’s unpaid childcare burden increases their productivity and income.
2. To examine the factors that impede access to parenting care facilities among vulnerable women engaged in business markets in Uganda and how these could be mitigated.
3. Evaluate the effects of parenting care facilities, financial subsidy and parents’ training on the productivity of mothers and profitability of their businesses.
4. To inform government action through tested and proven models for scaling up parenting care corners to both structured and unstructured markets
5. To provide proof of concept on how governments can introduce affordable, effective, and sustainable childcare models that work for vulnerable mothers who work in informal markets in Uganda.

Norway 2021-10-01 2024-10-01 Social Science and Humanities Non-Clinical Trial Non-degree Award
Aida Cuni Sanchez
ID:
Monitoring forest dynamics in Bwindi National Park
REFNo: NS282ES

• Does tree growth change with increasing altitude?
• How do taxonomic, forest structural and environmental attributes affect tree growth?
• How do carbon stocks change over time at different altitudes?

 Spain 2021-10-01 2024-10-01 Natural Sciences Non-Clinical Trial Non-degree Award
Radhika Sundararajan Lu
ID:
A pilot study of adherence support delivered by informal health providers to improve entry to and retention in HIV care in rural Uganda
REFNo: HS1747ES

: Pilot test the adapted intervention to evaluate implementation and impact on linkage/retention in HIV and ART adherence among individual PLWH,Adapt an evidence-based layperson adherence support curriculum for delivery by TH.,
 USA 2021-10-01 2024-10-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
 Evaluation of Clinical Chemistries from Biospecimens Collected with a Painless Capillary Blood Collection TASSO SST Among a Subset of Patients Enrolled in an Observational Study of Sepsis in Uganda
REFNo: HS1751ES

We plan to compare capillary chemistry values collected via the painless Tasso collection device to standard serum chemistry values collected via venipuncture at a single study visit (Day 28 of the main study(HS 2292)) for each consenting participant. We plan to evaluate the correlation between chemistry values from capillary versus venous blood collection and identify any scenarios where the values diverge such as for high or low values or for specific analytes collected in a remote field location. We plan to review the failure rate and causes for failure for the Tasso device
 Uganda 2021-10-01 2024-10-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Moses Ntaro
ID: UNCST-2020-R014133
 Effect of student community engagement on sanitation behavior: a case of Community Led Total Sanitation in Kabale District
REFNo: HS1135ES

To evaluate the effect of students community engagement on household level ODF status in Kabale District, Uganda so as to demonstrate the contribution of students in improving CLTS implementation and outcomes
 Uganda 2021-09-29 2024-09-29 Medical and Health Sciences Degree Award
Mohammed Lamorde
ID: UNCST-2019-R001293
 Infant extended safety follow-up study – an observational study of brain imaging and child development in infants (DolPHIN-2 PLUS)
REFNo: HS1639ES

1. To determine if there are developmental differences following exposure to DTG or EFV. 2. To examine brain structure and microstructure of HEU children. 3. To determine developmental outcomes. 4. To validate the Hyperfine, low-field MRI system 5. To explore the impact of environmental factors such as antenatal iron-deficient anaemia on brain development in a high-risk birth cohort
Nigeria 2021-09-29 2024-09-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Tom  Ngabirano Denis
ID: UNCST-2020-R014491
 Effect of Enhanced Neonatal Jaundice Education on Knowledge, Early Detection and Care Seeking by Postnatal Mothers at Jinja Regional Referral Hospital
REFNo: HS1479ES

Objectives General objective To improve mothers’ knowledge of neonatal jaundice for early detection, proper care and prevention of severe neonatal jaundice. Specific objectives 1. To assess the level of mothers’ knowledge about neonatal jaundice at JRRH. 2. To implement an enhanced neonatal jaundice education package for postnatal mothers at JRRH. 3. To assess the effect of an enhanced neonatal jaundice education package on the level of knowledge, early detection and care seeking by postnatal mothers at JRRH.
 Uganda 2021-09-29 2024-09-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Lukia Namaganda Hamid
ID:
Malnutrition as a probable predictor of mortality in cerebral palsy (CP), and the effect of positive deviance and parent facilitator training strategies to malnutrition and caregiving among children and adolescents with CP in the Iganga, Mayuge and Bugweri rural districts of eastern Uganda
REFNo: HS1427ES

Specific Objectives:
1. To assess mortality and whether malnutrition is one of the predictors among a population based sample of children and adolescents with cerebral palsy the Iganga Mayuge-Health and Demographic Surveillance Site (IM-HDSS), Uganda
2. To assess the difference in the change in nutritional status in 2015 and 2019 among children with CP compared to their age and sex matched controls without CP at the IM-HDSS, Uganda.
3. To explore positive and negative nutrition practices among caregivers of well-nourished and under-nourished children with cerebral palsy respectively at the IM-HDSS, Uganda.
4. To determine the difference in the effectiveness of the positive deviance strategy and parent facilitator trainings on CP child and adolescent malnutrition and caregiving within the Iganga, Mayuge and Bugweri districts, Uganda.

 Uganda 2021-09-29 2024-09-29 Medical and Health Sciences Clinical Trial Degree Award
Scholastic Ashaba
ID: UNCST-2023-R007613
 Self-management among adolescents living with HIV in Uganda
REFNo: HS1697ES

Aim 3: Assess feasibility, acceptability, and preliminary effects of the self-management intervention on HIV outcomes for ALHIV transitioning to adult HIV care,Aim 2: Develop a self-management intervention that will enable ALHIV to successfully transition to adult HIV care,Aim 1: Use qualitative research to elaborate a conceptual model of the barriers faced by ALHIV transitioning to adult HIV care in Uganda,
 Uganda 2021-09-29 2024-09-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Willy Ssengooba
ID: UNCST-2022-R001801
 Evaluation of a new stool-based qPCR for TB diagnosis in children and people living with HIV: a multicentre study in Eswatini, Mozambique and Uganda
REFNo: HS1615ES

To create a biorepository of well characterized pediatric samples at each of the study sites to support the future development and evaluation of novel biomarker research. ,To evaluate the quantitative stool qPCR platform as a tool to monitor treatment response in children and PLHIV,To compare the diagnostic performance of the stool qPCR platform to individual sputum and stool Xpert Ultra, urine LAM, sputum smear, sputum (MGIT) culture results against a clinical diagnosis and bacteriological reference standard,To evaluate the diagnostic accuracy of the stool Mtb qPCR tool compared to a composite reference standard (sputum and stool Xpert Ultra, sputum culture and urine TB-LAM) and clinical diagnosis. ,
 Uganda 2021-09-29 2024-09-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Lillian Wambuzi Ogwang
ID: UNCST-2021-R013189
 Seroprevalence of SARS-CoV-2 based on antibody testing among HIV infected mothers and their children in the PROMOTE Cohort at the MU-JHU Research Collaboration: July 2020 through June 2021 SUBSTUDY Version 2.0 Dated 16 Jun 2021
REFNo: HS1658ES

1. To determine the seroprevalence of COVID-19 IgG antibody among PROMOTE women living with HIV on antiretroviral therapy, and their HIV exposed children enrolled in PROMOTE; based on Roche ELISA antibody testing of plasma samples collected July 2020 to Jun 2021• To determine the association of COVID-19 exposure and PROMOTE participant characteristics such as age, CD4 count, BMI, maternal ARV therapy, pregnancy, Breast feeding, maternal Viral load, hospitalization in the past year with SARS-CoV-2 antibody positivity, comorbidity diagnosis (e.g. hypertension, obesity, asthma, TB, pulmonary, cardiac, renal disease, sickle cell disease).

3• To use PROMOTE data to determine maternal and pregnancy outcomes among PROMOTE women who were found to have had COVID-19 infection during pregnancy based on antibody testing during the period July 2020 - June 2021.

Uganda 2021-09-29 2024-09-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 Evaluation of the performance of the Salmonella Biolineâ„¢ typhi IgG/IgM Fast test in a near-patient testing environment, including evaluation of usability
REFNo: HS1700ES

To evaluate the usability of the Biolineâ„¢ Salmonella typhi IgG/IgM Fast test in the near-patient environment using a questionnaire based survey. ,To establish the performance of the Biolineâ„¢ Salmonella typhi IgG/IgM Fast test in a near-patient setting compared to the performance in a professional lab (i.e. Central Public Health Laboratory) using venous whole blood samples. ,
 Uganda 2021-09-29 2024-09-29 Medical and Health Sciences Clinical Trial Non-degree Award
Martin Ariapa
ID: UNCST-2021-R013296
 Play and Learning in Children’s Eyes
REFNo: SS1022ES

To develop the Children’s Experiences of LtP Protocol (CELP) with its corresponding modules and items, intended for use by a coach or instructional support staff, by soliciting direct insights from children about their LtP experiences. To develop the Formative Observation and Reflection Assessment (FORA) with its corresponding modules and items, intended for use by ECD and primary education teachers as they implement a LtP practice in the classroom. To develop and validate a set of formative tools designed to help teachers in low-and middle-income countries assess and improve their practice in Learning through Play (LtP), through a deeper understanding of how children experience LtP in their classrooms,
 Uganda 2021-09-29 2024-09-29 Social Science and Humanities Non-Clinical Trial Non-degree Award
herbert  Itabangi Itabangi
ID:
Metabolic and Molecular ecological evolution of opportunistic Pulmonary fungal co-infections (MeMoF project)
REFNo: HS1233ES

1. To determine the burden and aetiological profiles of fungal-co-infections among patients with chronic pulmonary disease suspected for Tuberculosis
2. To establish and characterise microbial communities associated with chronic pulmonary disease.
3. To characterise potential interaction relationships established between fungal and bacterial communities.

Uganda 2021-09-27 2024-09-27 Medical and Health Sciences Non-degree Award
Emmanuel Sendaula
ID: UNCST-2020-R014767
 Utilization of ART and TB treatment during the COVID-19 pandemic: A case of Kampala District
REFNo: HS1471ES

To determine the level of ART and TB treatment utilization among patients during the COVID-19 pandemics in Kampala district
To determine the factors associated with ART and TB treatment utilization among patients during the COVID-19 pandemic in Kampala district
To estimate the incidence rate of loss to follow-up among patients during the COVID-19 pandemics in Kampala district

Uganda 2021-09-24 2024-09-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Paul Kiondo
ID:
RISK FACTORS OF GENETIC CONSTITUTION, AND PREDICTORS PERSISTENT DISEASE IN WOMEN WITH MOLAR PREGNANCY ADMITTED AT MULAGO HOSPITAL, KAMPALA, UGANDA: A CASE-CONTROL STUDY
REFNo: HS1442ES

1. To determine the social, medical and obstetric risk factors of HM in women admitted at Mulago hospital, Kampala, Uganda.
2. To outline the outcomes of HM in women admitted in Mulago hospital, Kampala, Uganda.
3. To describe the genetic constitution of HM in women admitted at Mulago hospital, Kampala, Uganda.
4. To determine the predictors of persistent disease in women with HM admitted at Mulago hospital.

 Uganda 2021-09-24 2024-09-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
FIONA ASIIMWE
ID:
DIAGNOSTIC ACCURACY OF ULTRASOUND AND ADVERSE NEONATAL OUTCOMES AMONG WOMEN WITH A DIAGNOSIS OF NUCHAL CORD DELIVERING AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS1531ES

General Objective
To determine the diagnostic accuracy of ultrasound in diagnosing nuchal cord and to compare the proportion of adverse neonatal outcomes between women with and without a diagnosis of nuchal cord among women delivering at Mbarara Regional Referral Hospital.

Specific Objectives
1.To determine the diagnostic accuracy of ultrasound in diagnosing nuchal cord among women delivering at Mbarara Regional Referral Hospital.

2.To compare the proportion of adverse neonatal outcomes between women with and without a diagnosis of nuchal cord delivering at Mbarara Regional Referral Hospital.

Uganda 2021-09-24 2024-09-24 Medical and Health Sciences Non-Clinical Trial Degree Award
Lawrence Mugisha
ID:
Evaluation of Wastewater-Based Epidemiology (WBE) tool for surveillance of COVID-19 in selected wastewater treatment plants and channels in Kampala-Entebbe Area, Uganda
REFNo: HS1725ES

Overall Objective: To provide COVID-19 surveillance data for a wider population based on wastewater monitoring as an early warning tool to inform outbreak response strategies
Specific Objective
1. To detect and characterize the SARS-CoV-2 virus in wastewater from wastewater treatment plants, channels and septic tanks of hospitals in Kampala and Entebbe
2. To evaluate and standardise the molecular detection methods for WBE


 Uganda 2021-09-24 2024-09-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 COMPARISON OF PERFORMANCE OF CAPILLARY BLOOD VS VENOUS BLOOD ON SYPHILIS ULTRA TEST DEVICE/ TEST REF: ISY-U402 AND CAPILLARY BLOOD VS VENOUS BLOOD ON SYPHILIS ULTRA RAPID TEST STRIP) REF: ISY-U401 USING SD BIOLINE VERSION 3.0 AS A REFERENCE
REFNo: HS1643ES

The objective of this evaluation is to demonstrate the equivalence of capillary (fingerprick) whole blood and venous whole blood on the Syphilis Ultra test device/ Test strip (Whole Blood/Serum/ Plasma) and strip.
2.4 Exploratory Objectives
• To determine the diagnostic accuracy of the Syphilis Ultra test device/ Test (Whole Blood/Serum/ Plasma) and strip.

 Uganda 2021-09-23 2024-09-23 Medical and Health Sciences Clinical Trial Non-degree Award
Christopher Dolan Gerald
ID:
Improving access and retention in inclusive education for refugee children with disabilities
REFNo: SS937ES

I.To explore stakeholder’s understanding of the processes, challenges and opportunities for refugee children in accessing and progressing in inclusive education
II.To establish the current capacity of the education system to deliver safe and inclusive quality education for refugee children with special needs and disabilities
III.To describe the extent to which RCSN and their caretakers access timely and appropriate support to improve their physical, psychological and social functionality
IV.To establish the extent to which Key stakeholders effectively champion social accountability and implementation of policies and commitments on inclusive education
V.To examine the daily needs of RCWD and their carers

UK 2021-09-23 2024-09-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Robens Mutatina
ID: UNCST-2021-R013633
 Psychosocial challenges and Coping Strategies among Caregivers of Children with Cerebral Palsy in South Western Uganda
REFNo: SS762ES

To determine the psychosocial challenges faced by caregivers of children with cerebral palsy attending MRRH in southwestern Uganda.

To describe the coping strategies of caregivers of children with cerebral palsy attending MRRH in southwestern Uganda.

 Uganda 2021-09-22 2024-09-22 Social Science and Humanities Non-degree Award
Samuel Biraro
ID:
Assessing the impact of COVID-19 on routine immunization demand and uptake, and understanding COVID-19 attitudes and perceptions in Uganda
REFNo: HS1679ES

1. Identify the range of factors affecting routine immunization uptake during the COVID-19 pandemic in order to inform key areas for mitigation intervention; and
2. Generate timely data on the range of factors that may influence demand and uptake of the COVID-19 vaccines among HCW and the public to identify strategies to promote optimal uptake of the COVID-19 vaccines.


Uganda 2021-09-22 2024-09-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mary  Nanteza Bridget
ID:
ASSESSING A UGANDAN COMMUNITY FOR ACCEPTABILITY, SHORT- AND LONG-TERM SIDE EFFECTS OF COVID-19 VACCINE UPTAKE AND THE COLLECTION OF RELEVANT BIOLOGICAL SPECIMENS TO SUPPORT IMMUNOLOGICAL, HOST, AND VIROLOGICAL STUDIES ON COVID-19 VACCINE.
REFNo: HS1660ES

STUDY GOAL AND OBJECTIVES
The overall objective of this study is to assess acceptability, document short and long-term side effects, characterize break-through viruses that are linked to COVID-19 vaccination, and collect specimens for studies aimed at understanding host, viral and immunological factors associated with COVID-19 vaccine.
Specific objectives:
1. To assess the community knowledge, attitudes and perceptions (KAP) towards COVID-19 vaccines.
2. To describe the short and long-term side effects of COVID-19 vaccine provided at the UVRI clinic
Blood specimens will be collected for the following immunological and virological studies below:
3. To describe the sensitivity of COV ID-19 breakthrough viruses to prior and co-existing anti-SARS-COV-2 antibody and cellular immune responses after immunization with or without prior history of COVID-19 infection; and to also isolate SARS-CoV-2 Spike-specific human monoclonal antibodies in volunteers with strong neutralization responses.
4. To describe the correlation between pre-COVID-19 vaccination immune status, and outcome of vaccine induced immunity in newly vaccinated persons.
5. To describe COVID 19 immune responses in unvaccinated and already vaccinated persons before and after incident infections
6. To describe break-through viruses following COVID-19 immunization among the vaccinated persons

7. To describe host genetic factors that could be relevant for immune protection and disease outcome

Uganda 2021-09-22 2024-09-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eleanor Namusoke Magongo
ID: UNCST-2021-R013199
 Transitioning children to Optimal Regimens of Paediatric Dolutegravir (TORPEDO) in Uganda
REFNo: HS1596ES

the primary objective for the study is to assess patients’/ caregivers’ preference for a paediatric DTG regimen over their previous regimen, when transitioned from another regimen.

 Uganda 2021-09-22 2024-09-22 Medical and Health Sciences Clinical Trial Non-degree Award
Jihane Farhat Ben
ID:
Evaluation of two strategies part of the Differentiated Services Delivery Models (DSDM) in Fishermen’s landing sites at Lakes George and Edward, Western Uganda.
REFNo: HS1574ES

The main objective of the study is to describe acceptability and outcomes (VL suppression and
retention) relevance of MSF Landing site activities for the target populations to reorient
activities and document best practices.
The specific objectives are:
- To measure the proportion of eligible patients who enrol in CCLADs and FTR
- To compare characteristics of patients choosing CCLAD with those choosing FTR
- To measure the retention in care in CCLADS and in FTR at 6 and 12 months
- To measure the viral suppression for patients enrolled in CCLADS and in FTR for at least 1 year
- To describe acceptability and relevance of DSDM, peer zonal leaders, peers at the health facilities, VIP clinic days, OJT/CMEs for health workers and the information points.

France 2021-09-22 2024-09-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
IVAN IBANDA
ID:
Diagnostic and Treatment Delay of Tuberculosis: An In-depth Analysis of the Health-Seeking Behavior of Patients and the Health System Response in Kampala District
REFNo: HS1654ES

To determine the patient and system related factors that contribute to both diagnosis and treatment delays in Kampala District,To determine the proportion of patients that have a treatment delay for tuberculosis in Kampala District.,To determine the proportion of patients with tuberculosis diagnostic delay in Kampala District.,To evaluate the extent of diagnostic and treatment initiation delays of TB patients, identify the major contributors to such delays (patient or system), and study their various determinants.,
 Uganda 2021-09-22 2024-09-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Goylette Chami
ID: UNCST-2023-R006262
 SchistoTrack: Determinants of schistosomiasis infection and morbidity as part of the Oxford-Uganda Collaboration on Schistosomiasis
REFNo: HS1664ES

Determine whether infection indicators are informative for measuring morbidity risks
associated with schistosomiasis;
2. Prioritize the most common morbidities associated with schistosomiasis, by age, that
require treatment and further research;
3. Understand the relative importance of environmental factors versus current infections for
schistosomiasis- associated morbidities.
4. Assess the feasibility of large-scale tracking of individuals with wearable GPS;
5. Determine whether spatial indicators from wearable devices can better predict individual
infection risk when compared to conventional approaches such as household surveys;
and
6. Develop methods to classify water contact sites based on individual usage and
contamination to understand whether there are focal points for transmission or super
spreaders.
USA 2021-09-22 2024-09-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Freddy Kitutu Eric
ID: UNCST-2020-R014751
 Development and implementation of a patient-centred peer support intervention to promote the detection, reporting and management of adverse drug reactions among people living with HIV in Uganda
REFNo: HS1206ES

To estimate the effectiveness of the peer support intervention on the rate of ADR-reporting by PLHIV receiving DTG and/or IPT in Uganda,To describe the patterns of ADR-reporting (number, rate, time to reporting, seriousness) by PLHIV receiving DTG and/or IPT in whom the peer support intervention is implemented in Uganda,To determine the barriers and facilitators to implementation of the peer support intervention to promote ADR detection, reporting and management among PLHIV on DTG and/or IPT in Uganda,To develop an innovative peer support intervention for promoting the detection, reporting and management of ADRs in PLHIV receiving DTG and/or IPT in Uganda,
 Uganda 2021-09-21 2024-09-21 Medical and Health Sciences Non-degree Award
Maxson Anyolitho Kenneth
ID: UNCST-2021-R013447
 Community Engagement and Schistosomiasis Prevention: A Sociological Analysis of the Citizen Science Model among Selected Communities of Western Uganda
REFNo: SS836ES

Purpose of the study
The purpose of the study is to examine the effectiveness of the Citizen Science model in community engagement to the prevention of schistosomiasis among selected communities of western Uganda. To do this, the study will determine the socio-cultural barriers to the uptake of preventive measures to guide in the development of health education initiatives that can be executed by the Citizen Scientists to help change the behaviour of the community for the prevention of schistosomiasis.

Objectives of the study
This shall be guided by the following research objectives:
1. To determine the level of knowledge, attitude, and practice regarding schistosomiasis among communities of Western Uganda;
2. To explore the health-seeking practices, attitudes, and behaviour associated with schistosomiasis prevention among communities of Western Uganda
3. To understand the lived experiences and perceptions of schistosomiasis by communities of Western Uganda to determine how citizen scientists can be useful in shaping community perspectives
4. To develop and implement contextualized communication strategies for schistosomiasis prevention based on the outcome of the objectives above with help of the citizen scientists
5. To assess the role of the citizen science model of community engagement in the prevention of schistosomiasis among communities of western Uganda

 Uganda 2021-09-21 2024-09-21 Social Science and Humanities Non-Clinical Trial Degree Award
JOSELYN RWEBEMBERA
ID: UNCST-2021-R013915
 Rheumatic Heart Disease Community Streptococcal Treatment Program “RESET”
REFNo: HS1580ES

To improve the algorithm of the Strepic® device for Group A Strep Pharyngitis detection and then to test the performance as compared to microbiological culture (gold standard) and clinical decision rule.,To increase health seeking behavior for sore throat through a multifaceted community awareness campaign.,To improve guideline-based care through frontline healthcare provider education on clinical decision rules and guideline-based care through frontline healthcare provider education on clinical decision rules and guideline-based primary prevention.,To determine the impact of a pragmatic RHD primary prevention program in Uganda,
 Uganda 2021-09-21 2024-09-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ELIZABETH NALINTYA
ID: UNCST-2021-R012882
 Long title: A community-based Phase III, cluster randomized trial of point-of-care CD4 testing and enhanced screening and prophylaxis in advanced HIV disease Short title: An enhanced package of care to reduce mortality in advanced HIV disease
REFNo: HS1605ES

Primary Objectives:
1. To assess 24-week survival with retention in care in persons with advanced HIV disease (CD4<200 cells/µL) with point-of-care CD4 testing compared to standard flow cytometry
2. To assess 24-week survival with retention in care with an enhanced diagnostic OI screening and prophylaxis strategy compared to standard WHO package of care in persons with advanced HIV disease
Secondary Objectives:
1. To determine incidence of OIs
2. To measure adverse events with enhanced prophylaxis regimens
3. To assess tolerability and adherence of enhanced prophylaxis regimens
4. To determine incidence and cause of hospitalization for persons with advanced HIV disease
5. To determine cause of death for persons with advanced HIV disease
6. To determine HIV outcomes of viral suppression in persons with advanced HIV disease.
7. Measure cost, cost-effectiveness, and budgetary impact of the CD4 testing strategies, and OI screening and prophylaxis strategies.

 Uganda 2021-09-21 2024-09-21 Medical and Health Sciences Clinical Trial Non-degree Award
Graham Birch John
ID:
Title of research project: Oxidative shielding and the inter-generational costs of reproduction in male wild banded mongooses
REFNo: NS164ES

(1) To understand transgenerational influences on health and reproductive success in
wild mammals.
(2) To investigate the impact of paternal health on the development and reproductive
success of offspring, using banded mongooses as a model system.
 UK 2021-09-20 2024-09-20 Natural Sciences Degree Award
Fabian Mwosi
ID:
RETIREMENT PLANNING AND SOCIO-ECONOMIC STATUS OF CIVIL SERVANTS IN BUSOGA SUB-REGION, UGANDA.
REFNo: SS843ES

i. Investigate the relationship between saving culture and socio-economic status of retired civil servants in Busoga sub-region, Uganda
ii. Examine the relationship between financial planning and socio-economic status of retired civil servants in Busoga sub-region, Uganda
iii. Assess the relationship between lifestyle and socio-economic status of retired civil servants in Busoga sub-region, Uganda
iv. Explore the moderating effect of demographic factors on the relationship between retirement planning and socio-economic status in Busoga sub-region, Uganda
 Uganda 2021-09-20 2024-09-20 Social Science and Humanities Non-Clinical Trial Degree Award
Asenath Kwagalakwe
ID:
Dry Rifting in the Albertine-Rhino graben, Uganda (DRIAR)
REFNo: NS252ES

Investigating the physics of strain accommodation in the magma-poor Albertine-Rhino Graben of the East African Rift System using geodynamic modeling and GNSS geodesy
 Uganda 2021-09-20 2024-09-20 Natural Sciences Non-Clinical Trial Degree Award
Hillary Mwongyera
ID:
Dry Rifting in the Albertine-Rhino Graben (DRIAR)
REFNo: NS264ES

To conduct a geological investigation of faulting associated with continental rifting in the magma-poor rift environment in the northernmost Western Branch of the East African Rift System.
 Uganda 2021-09-20 2024-09-20 Natural Sciences Non-Clinical Trial Degree Award
Eleanor Namusoke Magongo
ID: UNCST-2021-R013199
 Determining the Effectiveness of Dispensing Messages (DEDIM) on Adherence and Viral Suppression among Children with an Unsuppressed Viral Load in Uganda
REFNo: HS1544ES

General Objective
To determine the effectiveness and implementation of dispensing messages on adherence and viral suppression among children with an unsuppressed viral load in Uganda

Specific objectives
1. To determine the facilitators and barriers to the delivery of dispensing messages to caregivers of children (< 15 years) living with HIV with an unsuppressed viral load in Uganda to inform the implementation strategy.
2. To assess the effectiveness of dispensing messages on outcomes of adherence and viral load suppression among children (<15 years) living with HIV with non-suppressed viral loads in Uganda.
3. To identify processes and contextual factors that explain the uptake, reach, and fidelity of delivery of ART dispensing messages to caregivers of children (< 15 years) living with HIV with unsuppressed viral load in Uganda

 Uganda 2021-09-20 2024-09-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eve  Namisango
ID: UNCST-2021-R014038
 The development and evaluation of a mobile phone-based intervention to facilitate continuity of care, symptom monitoring and self-management in palliative care patients in Uganda
REFNo: HS1600ES

vi. To develop best practices for patient-public engagement to empower cancer patients to support research in palliative care at different stages,v. To identify mechanisms of action for the intervention in supporting palliative care patients and their families ,iv. To determine uptake, patterns of clinical palliative care practice and factors influencing engagement with the mobile application ,iii. To deliver the novel intervention to two cohorts of palliative care patients , ii. To determine optimal implementation within routine palliative care practice at Yumbe Regional referral hospital palliative care unit and New Life Hospice ,i. To develop and evaluate a mobile phone-based (mpalliative) intervention to collect outcomes data and COVID-19, TB and hepatitis B symptoms from palliative care patients alongside developing a web-based application to communicate data to palliative care teams and facilitate continuity of care and self-management in palliative care patients in Uganda ,
 Uganda 2021-09-20 2024-09-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Achilles Katamba
ID: UNCST-2019-R000540
 Uganda TB Care Cascade
REFNo: HS1718ES

1. To evaluate the accuracy of DHIS2 TB surveillance data using quantitative and mixed-methods approaches. 1a. To compare the accuracy of TB quality indicators measured with aggregate data compared to those measured with individual-level data. 1b. To explore discrepancies in the DHIS2 data using qualitative interviews.
2. To use routine surveillance data to describe the quality of TB care in Uganda.
3. To measure the impact of Xpert MTB/RIF on TB indicators in Uganda.
 Uganda 2021-09-20 2024-09-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nelson Sewankambo K
ID: UNCST-2020-R014578
 THRiVE Research Enrichment: Community and Public Engagement for Enhanced Impact
REFNo: HS1586ES

1. To enable doctoral trainees to work with young people in schools who will identify their preferred ways for engagement with THRiVE research.
2. To co-create and co-design at least one engagement project at each school led by student champions in collaboration with doctoral trainees and implemented based on one or more ways identified in objective 1 above.
3. To co-design and implement at least one student-centred drama skit and/or games for engagement of students with THRiVE doctoral trainees’ research, utilizing findings from objective one.
4. To publicize the public engagement in research work to stakeholders as a way of stimulating engagement of young people and doctoral trainees in PER.

Uganda 2021-09-17 2024-09-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jane  Namusisi
ID: UNCST-2021-R013619
 seizure control and associated factors among children with epilepsy at Mbarara Regional Referral Hospital
REFNo: HS1657ES

MAIN OBJECTIVE
To determine the seizure control status and describe its associated factors among children attending the Epilepsy Clinic at MRRH for at least six months.
SPECIFIC OBJECTIVES;
1. To identify the seizure types among children under care for at least six months at the Epilepsy Clinic, MRRH.
2.To determine the proportion of children with epilepsy with poor seizure control under care for at least six months at the MRRH Epilepsy clinic.
3.To identify the factors associated with poor seizure control among children under care for at least six months at the MRRH Epilepsy clinic.

Uganda 2021-09-17 2024-09-17 Medical and Health Sciences Non-Clinical Trial Degree Award
Achilles Katamba
ID: UNCST-2019-R000540
 Human-Centred Design and Communities of Practice to Improve Delivery of Home based Tuberculosis Contact Investigation in Uganda
REFNo: HS1720ES

General Objective: The study aims to assess the effectiveness of an enhanced intervention strategy for implementing TB contact investigation relative to usual care. Specific Objectives: 1.To compare the implementation, effectiveness, and public health impact of TB contact investigation delivered via an enhanced intervention strategy vs. the usual care strategy in a stepped-wedge, cluster-randomized implementation trial. 2.To identify implementation processes and contextual factors that influence the effectiveness of the intervention strategy for TB contact investigation. 3.To compare the costs and epidemiological impact of the intervention and usual care strategies for TB contact investigation.
Uganda 2021-09-17 2024-09-17 Medical and Health Sciences Clinical Trial Non-degree Award
Susan  Nabadda
ID: UNCST-2020-R014331
 SeqCOVID consortium: EAC participation – Sequencing of COVID-19 isolates from the East African Region
REFNo: HS1592ES

Epidemiological Analysis of current COVID outbreak,Capacity Building in East Africa and setting up of Prospective COVID Surveillance Platform,Diagnostic and Vaccine Development for East African COVID variants: - describe East African COVID variants and predict immunogenic epitopes and drug targets in silico, The aim of the present project is for the East African region to actively contribute data for COVID-19 drug and vaccine development, to equip the region for the time after a vaccine and drugs were developed and also to prepare for future outbreaks.,
 Uganda 2021-09-16 2024-09-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Grace Nalumu
ID:
ASSESSING FACTORS ASSOCIATED WITH NEONATAL DEATHS IN BUSIA DISTRICT; CASE STUDY OF MASAFU, DABANI AND BUSIA HEALTH FACILITIES
REFNo: HS1711ES

1. To assess factors associated with neonatal deaths in Busia district such that we make recommendations, according to the findings, on what measures to adopted in order to reduce neonatal mortality in the district and the country,4. To examine health facility factors associated with neonatal deaths in Busia district,3. To establish neonatal related factors associated neonatal deaths in Busia district ,2. To determine maternal factors associated with neonatal deaths in Busia district ,
 Uganda 2021-09-16 2024-09-16 Medical and Health Sciences Non-Clinical Trial Degree Award
Janet SEELEY
ID:
Multimorbidity in Africa - Increasing Understanding of the Health Workers’ Experiences and Epidemiology (MAfricaEE)
REFNo: SS998ES

Explore the healthcare professionals' (HCPs) experiences of treating and managing patients with multi-morbidity in Uganda and what health workers see as the main barriers to optimal care provision. How do health care professiönals view the potential impacts of COVID-19 on care for patients with multi-morbidity?
 UK 2021-09-13 2024-09-13 Social Science and Humanities Non-Clinical Trial Non-degree Award
Frederick  Oporia
ID:
Improving use of seaworthy life jackets among boaters on Lake Albert, Uganda. A cluster randomized trial
REFNo: SS992ES

1. To estimate the prevalence of life jacket use among boaters on Lake Albert.

2. To identify the determinants of life jacket use among boaters on Lake Albert

3. To determine the seaworthiness of life jackets used by boaters on Lake Albert

4. To design a behavior change intervention aimed at improving use of seaworthy life jackets among boaters on Lake Albert

5. To pilot and evaluate the effectiveness of a behavior change intervention on improving use of seaworthy life jackets among boaters on Lake Albert

 Uganda 2021-09-10 2024-09-10 Social Science and Humanities Degree Award
Carolyn Pelnik
ID:
Identifying and Easing Constraints on Microenterprise Location within Kampala, Uganda
REFNo: SS935ES

This project asks whether business relocation within the city could increase profits for microfirms in Kampala, Uganda, and if so, then what frictions (constraints) restrict a firm’s ability to relocate without intervention. Ultimately, this project plans to use a multi-arm randomized experiment to accomplish 3 aims: to detect appetite for business relocation, whether relocation increases profits, and which of the tested frictions might constrain location choice. In the first phase of the research, the project will survey microfirms in Kampala to understand their current locations, how profits vary by location across the city, what aspirations the business owners have with respect to future business growth, and what challenges they perceive to accomplishing business growth.
USA 2021-09-10 2024-09-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Paineto Masengere
ID: UNCST-2021-R013195
 Perceptions, barriers, and facilitators of adoption of healthy lifestyles for cardiovascular disease prevention among slum communities in Kampala, Uganda
REFNo: HS1661ES

1. To explore how slum dwellers in Kampala district define a healthy lifestyle in the context of cardiovascular disease prevention.
2. To explore the barriers and facilitators to adopting recommended lifestyles for cardiovascular disease prevention among slum dwellers.
3. To explore the potential roles of community actors in slums in cardiovascular disease prevention.

Uganda 2021-09-10 2024-09-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Felix Oyania
ID: UNCST-2021-R013492
 Feasibility of Primary Repair for Anorectal Malformations in Uganda
REFNo: HS1632ES

To determine the feasibility of primary repair for anorectal malformations in Uganda.,
 Uganda 2021-09-10 2024-09-10 Medical and Health Sciences Non-Clinical Trial Degree Award
FRANK MULINDWA
ID:
Changes in insulin kinetics after withholding dolutegravir in Ugandan HIV patients who develop diabetes while on dolutegravir.
REFNo: HS1493ES

To determine changes in; insulin secretion, insulin sensitivity, insulin clearance and HBA1C at 24 weeks after DTG discontinuation in Ugandan HIV patients who develop diabetes while on DTG.
 Uganda 2021-09-09 2024-09-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Martha Musyoka Mbenia
ID:
PREDICTORS OF ADVERSE FETO-MATERNAL OUTCOMES AMONG MOTHERS ADMITTED WITH ANTEPARTUM HEMORRHAGE AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS1450ES

To describe adverse outcomes and determine predictors of adverse feto-maternal outcomes in mothers with antepartum hemorrhage at Mbarara Regional Referral Hospital
 Kenya 2021-09-09 2024-09-09 Medical and Health Sciences Clinical Trial Degree Award
Jimmyy Opee
ID:
PROPORTION AND FACTORS ASSOCIATED WITH INTRA-PROCEDURAL PAIN AMONG WOMEN UNDERGOING MANUAL VACUUM ASPIRATION FOR INCOMPLETE ABORTION AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS1462ES

General objective
To determine the proportion and factors associated with intra-procedural pain among women undergoing Manual Vacuum Aspiration for incomplete abortion at gynecology ward at Mbarara Regional Referral Hospital.

Specific objectives
1. To determine the proportion of women with intra-procedural pain undergoing Manual Vacuum Aspiration for incomplete abortion at gynecology ward at Mbarara Regional Referral Hospital.
2. To determine the factors associated with intra-procedural pain among women undergoing Manual Vacuum Aspiration for incomplete abortion at gynecology ward at Mbarara Regional Referral Hospital.

 Uganda 2021-09-09 2024-09-09 Medical and Health Sciences Non-Clinical Trial Degree Award
Ronald Mulebeke
ID:
A pilot study to assess the impact of Supportive Supervision and Behavior Change Communication at private health facilities in Uganda
REFNo: HS1588ES

This study will assess the impact of supportive supervision and behaviour change communication to improve the quality of malaria care and data management delivered by clinicians at private health facilities in Uganda.
Uganda 2021-09-09 2024-09-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ANTHONY KAYIIRA
ID: UNCST-2020-R014108
 Understanding Reproductive Health among Survivors of Paediatric and Young adults (URHSPY) Cancers: a mixed method study
REFNo: HS1652ES

To explore the knowledge, perceptions, and attitude of; parents or caretakers of children with cancer, and health workers on cancer treatment-related reproductive morbidity, at the Uganda Cancer Institute,To describe self-reported reproductive morbidity associated with cancer treatment among childhood and young-adult cancer survivors.,To establish the extent of reproductive morbidity associated with cancer treatment among young cancer survivors in Uganda. In addition, we aim to explore the contextual enablers and barriers to addressing cancer treatment-related reproductive morbidity in Uganda.,
 Uganda 2021-09-09 2024-09-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan  Nabadda
ID: UNCST-2020-R014331
 Study Protocol for the Evaluation of Covid 19 Antibody and Antigen Rapid Diagnostic Test (RDT) In the EAC Partner States
REFNo: HS1591ES

Evaluation of ELISA cross-reactivity on stored archived negative samples between East African Partner States. ,Evaluation RDT performance differences between the East African Partner States,- Evaluate the clinical specificity of antibody RDT and ELISA using serum/plasma specimens from COVID-19 negative specimens from pre-COVID-19 (archived stored samples),- Evaluation of COVID19 antibody RDTs and ELISA’s in the East African region, using serum/plasma samples from COVID-19 confirmed based on RT-PCR results (RT-PCR positive test results). ,Evaluation of COVID19 antigen RDTs against gold standard PCR in the East African region,
 Uganda 2021-09-09 2024-09-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan  Nabadda
ID: UNCST-2020-R014331
 Evaluation of TUBEX Typhoid TF IgM Antibody test for Early Diagnosis of Typhoid fever Among patients in Uganda
REFNo: HS1548ES

1) To carry out blood culture testing on all samples from patients with signs and symptoms of typhoid fever in the selected facilities of Uganda.
2) To carry out serological testing for Salmonella antibodies using the TUBEX Typhoid TF IgM Antibody test on the serum samples of consented/assented patients whose samples grew Salmonella Typhi.

 Uganda 2021-09-09 2024-09-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Fred Nalugoda
ID: UNCST-2021-R013343
 Exploring the impact of out-migration on remaining partners’ HIV and sexual behavior perceptions and practices in Rakai, Uganda: a qualitative study.
REFNo: SS981ES

The overall aim of this study is to qualitatively explore the impact of out-migration amongst heterosexual couples on non-migrating partners’ HIV and sexual behavior perceptions and practices in Rakai, Uganda.
Uganda 2021-09-09 2024-09-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jafesi Pulle
ID: UNCST-2020-R014213
 TRUST IN MEDICAL RESEARCH AMONG PATIENTS AT A REGIONAL REFERRAL HOSPITAL AND COMMUNITY MEMBERS IN LIRA DISTRICT, NORTHERN UGANDA
REFNo: HS1685ES

Explore community perceptions of trust in medical research,2. Determine the other factors associated with trust of medical research,1. Compare level of trust for medical research among community members and persons that are hospitalized.,To compare the level of trust in medical research among people hospitalized at a hospital and the community members, identify associated factors and explore prevailing community perceptions of trust in medical research.,
 Uganda 2021-09-09 2024-09-09 Medical and Health Sciences Non-Clinical Trial Degree Award
Daniel Mongovin David Thomas
ID:
Dry Rifting in the Albertine-Rhino Graben (DRIAR)
REFNo: NS160ES

To conduct a geological investigation of faulting associated with continental rifting in the magma-poor rift environment in the northernmost Western Branch of the East African Rift System.
 USA 2021-09-08 2024-09-08 Natural Sciences Non-Clinical Trial Degree Award
Julian Bagyendera Kobutungi
ID:
Gender, Youth and Social Inclusion Baseline Assessment for the USAID Local Partner Health Services – Ankole (USAID LPS – Ankole)
REFNo: SS1002ES

The main objective is to conduct a mixed method gender and youth social inclusion assessment which includes a literature review; collection of primary quantitative and qualitative data.,
 Uganda 2021-09-08 2024-09-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Nixon Niyonzima
ID: UNCST-2020-R014577
 UNDERSTANDING PATHOGENESIS OF BURKITT LYMPHOMA TO DEVELOP BETTER TREATMENTS FOR AFRICAN ENDEMIC BURKITT LYMPHOMA
REFNo: HS1546ES

4. To establish a BL tumor biorepository at the Uganda Cancer Institute ,3. To generate PDX mouse models of BL to understand the molecular factors that govern response to COM therapy in children with endemic BL at the Uganda Cancer Institute. ,2. To describe the molecular differences between endemic BL and sporadic BL. ,1. To determine the molecular profile of endemic BL tumors at the Uganda Cancer Institute,
 Uganda 2021-09-08 2024-09-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 PERFORMANCE EVALUATION OF COVID-19 ANTIGEN RAPID DIAGNOSTIC TESTS
REFNo: HS1690ES

To determine the association of positive index test results with disease stage (days since symptom onset, e.g. acute, early, late), symptom severity and symptom severity.,To determine the diagnostic accuracy of SARS-CoV-2 Ag RDTs on a respiratory specimen (NP swab, OP swab, nasal swab, saliva), vs Cobas SARS-CoV-2 assay as performed in patients presenting with influenza-like illness.,
 Uganda 2021-09-08 2024-09-08 Medical and Health Sciences Clinical Trial Non-degree Award
Pontiano Kaleebu
ID: UNCST-2021-R013577
 A clinical trial to assess the safety and immunogenicity of LNP-nCOV saRNA-02, a self-amplifying ribonucleic acid (saRNA) vaccine encoding the S glycoprotein of SARS-CoV-2, the causative agent of COVID-19, in SARS-CoV-2 seronegative and seropositive Uganda population
REFNo: HS1641ES

Primary Objective:

• To compare the safety and immune responses for SARS-CoV-2 seronegative and seropositive individuals from two immunisations with LNP-nCOV saRNA-02 administered IM 4 weeks apart at one dose level in 42 participants age 18-45 years.

Exploratory Objectives:
• To characterise the humoral and cellular immune responses to LNP-nCOV saRNA-02 administered at one dose given at 0 weeks and 4 weeks for individuals seronegative and seropositive for SARS-CoV-2 antibodies
• To characterise the profile of class and sub-class of antibody responses
• To characterize infection induced immune responses in participants with naturally acquired infection who are also exposed to the vaccine

 Uganda 2021-09-08 2024-09-08 Medical and Health Sciences Clinical Trial Non-degree Award
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