Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Ounyesiga Living
ID: UNCST-2024-R005177
 MODELING, SIMULATION AND OPTIMIZATION OF SOLAR POWER GENERATION AND TRANSMISSION IN UGANDA
REFNo: SIR322ES

Objectives of the Study
General Objective. The main objective of the study is to model, simulate and optimize solar power generation and transmission in Uganda.
Specific Objectives
The specific objectives are as follows:
(i) To modify the traditional power loss objective function in order to minimize electric power losses on Ugandan electricity transmission lines
(ii) To develop a mathematical models for coupled and uncoupled transmission lines, which can simulate lossy and lossless transmission parameters of current, voltage and temperature.
(iii) To formulate a differential equation for solar power generation and multiple empirical models for improving Photo Voltaic (PV) system design and operations.

 Uganda 2024-05-07 12:37:34 2027-05-07 Engineering and Technology Non-Clinical Trial Degree Award
ANTHONY ONONO JAMES
ID:
FACTORS ASSOCIATED WITH HEALTH CARE WASTE MANAGEMENT PRACTICES AMONG HEALTHCARE WORKERS IN GULU CITY
REFNo: HS4009ES

3. To identify healthcare system factors associated with effective healthcare management practices among healthcare workers in Gulu city, located in Northern Uganda.,2. To assess individual factors associated with the management of healthcare waste by healthcare staff in Gulu city, located in the northern region of Uganda.,1. To assess the healthcare waste management practices among healthcare workers in Northern Uganda\'s Gulu city.,To assess factors associated with healthcare waste management practices among health care workers in Gulu city. ,
 Uganda 2024-05-07 12:36:35 2027-05-07 Medical and Health Sciences Non-Clinical Trial Degree Award
Ntirandekura  Moses
ID: UNCST-2023-R005665
 GOOD GOVERNANCE AND WOMEN ECONOMIC EMPOWERMENT IN SELECTED DISTRICTS OF SOUTH WESTERN UGANDA: A STUDY OF UGANDA WOMEN ENTREPRENEURSHIP PROGRAMME (UWEP)
REFNo: SS2612ES

i. To establish the effect of accountability in implementation of UWEP on women economic empowerment in Kisoro and Kabale Districts of South Western Uganda. ii. To examine the extent to which transparency in implementation of UWEP affects women economic empowerment in Kisoro and Kabale Districts of South Western Uganda. iii. To determine the influence of participation in implementation of UWEP on women economic empowerment in Kisoro and Kabale Districts of South Western Uganda. iv. To identify how equitability and inclusiveness in implementation of UWEP affect women economic empowerment in Kisoro and Kabale Districts of South Western Uganda. v. To determine the relationship between gender regulatory policies and women economic empowerment in Kisoro and Kabale Districts of South Western Uganda.
Uganda 2024-05-07 12:35:04 2027-05-07 Social Science and Humanities Non-Clinical Trial Degree Award
Alison Comfort
ID: UNCST-2022-R011501
 Social networks and their role in early initiation of antenatal care by HIV serostatus in Uganda
REFNo: HS4061ES

Through a quantitative survey data collection using a prospective cohort design, this study aims to: 1) Understand whether there exists an association between social network characteristics and early ANC initiation; 2) Explore whether visualizing social network characteristics differentially affects care-seeking intentions at delivery; 3) Characterize the social network characteristics of pregnant women seeking ANC and assess whether differences exist by serostatus; 4) Assess whether network characteristics are differentially associated with early ANC initiation depending on serostatus, with similar analyses for other perinatal care indicators (e.g., facility-based delivery, post-partum care and infant HIV testing if applicable)
USA 2024-05-07 12:25:25 2027-05-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Barnabas Atwiine
ID: UNCST-2022-R010629
 Assessing Implementation and Effectiveness of a Cash Incentive Family Support Intervention to Reduce Treatment Abandonment and Increase Survival among Children with Cancer in Sub-Saharan Africa
REFNo: HS3897ES

1. To assess the effectiveness of the intervention on end-of-treatment survival without evidence of disease.
2. To assess the proportion of eligible caregivers that access all planned mobile money instalments throughout the course of treatment.
3. To assess the cost-effectiveness of the intervention within the health system of participating
countries by WHO-CHOICE standards; defined as a cost less than three times the annual per
capita income per disability adjusted life year (DALY) averted.
4. To describe the views of stakeholders (policy makers, health providers and clients) on the acceptability and feasibility of the intervention.
Uganda 2024-05-07 11:43:52 2027-05-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Simran Prasad
ID:
Male reproductive skew, female codominance and mate choice, and inbreeding avoidance in wild vervet monkeys (Chlorocebus pygerythrus).
REFNo: NS801ES

The purpose of this project is to investigate the relationship between male dominance rank and mating and paternity success, degree of reproductive skew, female codominance and mate choice, and the direction of inbreeding avoidance in a population of vervet monkeys (Chlorocebus pygerythrus) at Lake Nabugabo, Uganda.
Canada 2024-05-07 11:24:53 2027-05-07 Natural Sciences Non-Clinical Trial Degree Award
MUWANGUZI MOSES
ID: UNCST-2021-R013695
 Depression among pregnant teenagers receiving antenatal care from health facilities in Mbarara city, Southwestern Uganda
REFNo: HS3913ES

To determine the factors associated with depression among pregnant teenagers in Mbarara city, southwestern Uganda.,To determine the prevalence of depression among pregnant teenagers in Mbarara city, southwestern Uganda. ,To determine the prevalence and factors associated with depression among pregnant teenagers in Mbarara city, southwestern Uganda.,
 Uganda 2024-05-07 11:07:54 2027-05-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Samuel  Obakiro Baker
ID: UNCST-2019-R000065
 FORMULATION AND PRECLINICAL EVALUATION OF HERBAL PRODUCTS FOR MANAGEMENT OF DIABETES MELLITUS AND ITS COMORBIDITIES IN UGANDA
REFNo: HS4127ES

To analyze the phytochemical and pharmaceutical properties of the formulated herbal products,To assess the antidiabetic activity and toxicity of the formulated herbal products for the management of DM using in vitro and in vivo models,2. To formulate herbal products for management of DM ,1. To prioritize medicinal plants for formulation of herbal products for management of diabetes mellitus (DM),To develop standard herbal products for management of DM with proven preclinical evidence of efficacy and safety ,
 Uganda 2024-05-07 11:04:09 2027-05-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Pamela Mbabazi Byakwaga
ID:
KIZINO DANCE-MUSICKING: NEGOTIATING ETHNIC IDENTITY AMONG BAKIGA IMMIGRANTS IN RUBIRIZI DISTRICT, WESTERN UGANDA
REFNo: SS2261ES

To examine how kizino dance-musicking is used to negotiate kikiga ethnic identity in Rubirizi District ,To explore the continuity and change in the nature and context of kizino dance-musicking among the Bakiga in Kabale and Rubirizi Districts,To examine the nature of the ethnic identity of the Bakiga in Kabale and Rubirizi Districts,To examine how Bakiga immigrants negotiate their ethnic identity in Rubirizi District,
 Uganda 2024-05-07 10:45:55 2027-05-07 Social Science and Humanities Non-Clinical Trial Degree Award
DORAH NAMPIJJA
ID: UNCST-2022-R009694
 Acute Rheumatic Fever Biomaker Project; Preventing Rheumatic Injury Biomarker Alliance: the Leducq PRIMA Network
REFNo: HS4091ES

iv. To design and validate a point of care diagnostic test for early ARF diagnosis,iii. To perform unbiased biomarker screens for ARF among children with ARF and to apply rigorous statistical analyses to identify biomarker(s) with high predictive power for ARF diagnosis ,ii. To conduct a case control study to understand the factors associated with ARF and disease progression among children aged 5-18 years,i. To create an Acute Rheumatic Fever registry and profile the phenotype among children with ARF aged 5-18 years,To identify accurate molecular biomarker(s) for ARF, and design a point of care diagnostic tool for early ARF diagnosis,
 Uganda 2024-05-02 12:45:10 2027-05-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Margaret Magumba Nakagolo
ID:
The Influence of the Adoption of the E-tax System on Tax Compliance in Uganda.
REFNo: SS2552ES

To establish ways in which online tax systems can be maximally utilised to improve tax compliance in Uganda.,To establish the association between the adoption of eTax and taxpayer demographics, and how that association affects tax compliance in Uganda.,To establish the association between the adoption of eTax and tax administration efficiency, and how that association affects tax compliance in Uganda. ,To establish the relationship between the adoption of eTax and the different elements of tax compliance (registration, filing and payment) in Uganda.,To determine the influence of the adoption of the eTax system on tax compliance in Uganda. ,
 Uganda 2024-05-02 12:43:39 2027-05-02 Social Science and Humanities Non-Clinical Trial Degree Award
Mathieu Chabry Eric
ID: UNCST-2024-R004404
 Toxoplasma in chimpanzees (Pilot study)
REFNo: NS789ES

This study is a pilot study which aims to look at the behavioral effects of the parasite Toxoplasma gondii in two populations of wild chimpanzees at the Budongo conservation field station. the project aims to understand correlations between infection and behaviors, to see if there are differences between infected and non infected individuals. The objectives of the research are the following:
- To see whether infection by the parasite toxoplasma gondii changes behavior of infected chimpaanzees by comparing infected and uninfected individuals (by comparing infected and non infected individuals)
- Establish infection status in a population of wild chimpanzees by collecting urine and check which individuals are infected and those which aren't (collecting urine non invasively)
- To see whether infection influences risky behaviors in wild chimpanzees (aggression towards higher ranking chimpanzees, foraging close to the borders of the territory)
- Determine if infection influences reaction to unfamiliar stimul (false fruits, remoted controlled animals maybe)
- Establish trends in behavior and compare infected and non-infected individuals
- Collect behavioral data in the purpose of establishing new studies possibilities
 Switzerland 2024-05-02 12:42:07 2027-05-02 Natural Sciences Non-Clinical Trial Degree Award
Charles Lwanga Tumuhe
ID:
Exploring perspectives of agroecology network organizations regarding their role in climate change adaptation in Uganda
REFNo: A409ES

To explore the understanding of agroecological initiatives made by the various network member organizations and their partners in their effort to help communities adapt to climate change.
To establish the perceived nature of the relationships and connections between agroecology as a movement and Climate Change adaptation

To establish the perceived benefits to network members from joint agroecological climate adaptation initiatives.

Uganda 2024-05-02 12:41:06 2027-05-02 Agricultural Sciences Non-Clinical Trial Degree Award
Irene Kinera
ID: UNCST-2022-R009689
 POST TB LUNG DISEASE AMONG CHILDREN IN UGANDA, A CROSS SECTIONAL STUDY
REFNo: HS3961ES

3. To assess the health-related quality of life of children and caregivers of children who were previously treated for PTB at Mulago National Referral Hospital.,2. To determine the correlation between clinical characteristics and lung function among children previously treated for PTB at Mulago National Referral Hospital.,1. To describe the clinical characteristics of PTLD among children previously treated for PTB at Mulago National Referral Hospital.,To describe the clinical characteristics of PTLD, assess the correlation between the clinical characteristics and lung function and to assess the health-related quality of life of children and caregivers of children who were previously treated for PTB at Mulago National Referral Hospital. ,
 Uganda 2024-05-02 12:39:55 2027-05-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Jenny Löfgren
ID: UNCST-2024-R005428
 Simulation-based training for mesh inguinal hernia repair under local anaesthesia - a randomized trial
REFNo: HS4058ES

Assess the learning curve of mesh inguinal hernia repair for novice learners and how it is affected by simulation based training prior to supervised surgery on patients.
Sweden 2024-05-02 12:38:06 2027-05-02 Medical and Health Sciences Clinical Trial Degree Award
Daniel Zaake
ID: UNCST-2019-R000923
 Infertility in Uganda: The Burden, quality of Life, lived experiences of individuals Diagnosed with infertility and Availability of services for Diagnosis and treatment of infertility.
REFNo: HS3901ES

1. To determine the prevalence and determinants of infertility in Uganda.
2. To evaluate the quality of life among individuals with infertility seeking fertility treatment in Kawempe National Referal Hospital (KNRH) and St Francis Hospital Nsambya(SFHN) in Kampala
3. To explore the lived experiences of couples and individuals diagnosed with infertility at KNRH and SFHN in Kampala
4. To assess the availability of services for diagnosis and treatment of infertility in Uganda.
Uganda 2024-05-02 12:37:00 2027-05-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Robert Waiswa
ID:
The enablers and barriers to remote work for persons with disabilities in Greater Kampala Metropolitan Area, Uganda
REFNo: SS2394ES

To create a deeper understanding of the enablers and barriers to remote work, including impacts on employability, for PWDs in Greater Kampala Metropolitan Area, principally to inform practice and policy in the design of interventions for disability-inclusive employment in Uganda as the country fast-tracks the UN Convention on the Rights of People with Disabilities, Sustainable Development Goal 10, and Vision 2040.,
 Uganda 2024-05-02 12:20:40 2027-05-02 Social Science and Humanities Non-Clinical Trial Degree Award
Sylvester Onzivua
ID:
A Postmortem Study to Explore the Pathological Basis of the Nodding Syndrome
REFNo: HS3048ES

(d) To compare the histological features in the various cases of the NS,c) To determine if there is any evidence of brain infection in NS. ,(b) To characterize the abnormal protein (tau) formation in the brain in NS. ,(a) To determine the main cellular processes occurring in the brain in the NS. ,Main Objective In the study postmortem brain samples will be used to explore the pathological basis of the NS. ,
 Uganda 2024-05-02 12:17:16 2027-05-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
CHARLES BATUME
ID: UNCST-2021-R013411
 Insecticidal and repellent properties of essential oils from catnip (Nepeta cataria) against Aedes aegypti, Anopheles gambiae s.s. and culex quinquefasciatus.
REFNo: HS1717ES

To confirm residual activity and application intervals.,To determine the optimum application dosage(s) and the residual activity.,To determine the efficacy of repellent formulations at the selected application rates against the target vector species.,To establish dose–response relations and determine the ED50 and ED95 of the active ingredient for vector repulsion.,To determine effectiveness of catnip (Nepeta cataria) as mosquito repellent for Ae. aegypti, Anopheles gambiae s.s, and Culex quinquefasciatus.,
 Uganda 2024-05-02 12:11:13 2027-05-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dominic Bagenda K
ID: UNCST-2021-R013132
 Predictors of Menstrual Hygiene Management among Adolescent Girls in a Rural Resource-deprived Setting in Bukedea District, Uganda.
REFNo: SS1065ES

iv. To quantify the effect of parental predictors on MHM practices among adolescent girls in a rural resource-deprived setting in Bukedea District.,iii. To quantify the effect of socioeconomic predictors on MHM practices among adolescent girls in a rural resource-deprived setting in Bukedea District.,ii. To quantify the effect of personal predictors on MHM practices among adolescent girls in a rural resource-deprived setting in Bukedea District.,i. To determine the proportion of adolescents practicing adequate MHM in a rural resource-deprived setting in Bukedea District.,Quantify the effects of personal, socioeconomic and parental predictors on MHM practices among adolescent girls in a rural resource-deprived setting in Bukedea District.,
 Uganda 2024-05-02 12:08:52 2027-05-02 Social Science and Humanities Non-Clinical Trial Degree Award
Peter Rukundo Milton
ID: UNCST-2020-R014799
 Testing efficacy and therapeutic potential of egg powder in prevention and management of moderate acute malnutrition: an intervention trial in drought-prone Karamoja, Northern Uganda
REFNo: HS2324ES

(i) Test the efficacy of powdered egg in the prevention of MAM and other related forms of malnutrition in children 6-59 months old. (ii) Assess the therapeutic potential of egg-based products in the management of MAM in the context of supplementary feeding.
Uganda 2024-05-02 12:04:25 2027-05-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Violet Korutaro
ID: UNCST-2019-R000618
 IMPAACT Early Career Investigator Award entitled, “Breastmilk Biomarkers of Inflammation, Immune Activation, and Human Milk Oligosaccharides (HMOs) in Women with vs. without Vertical Transmission During Breastfeeding
REFNo: HS4086ES

1. Determine the concentrations of total and various composition of human milk oligosaccharides (HMOs) (lacto-N-fucopentaose; lacto-N-neotetraose; lacto-N- tetraose; 2#-fucosyllactose; 3-fucosyllactose; and three #-sialyllactose); Immunoglobulin isotypes and subclasses (IgG1, IgG2b, IgG2c, and IgG3) in breastmilk of WWH at delivery (up to 5-days) and 4-6 weeks postpartum.

2. Assess the associations of HMO composition and immunoglobulin subclasses with breastmilk-associated HIV transmission.


 Uganda 2024-04-26 9:53:07 2027-04-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sylvia Nabukenya
ID: UNCST-2019-R000906
 Developing a guide for ethical review of AI-related research proposals involving human participants
REFNo: SS2558ES

I. To identify the gaps and challenges experienced by research ethics committees during review of AI-related health research projects
II. To examine the ethical considerations of health research involving human participants in AI research
III. To develop a guide for the review of AI-related research projects involving human participants.

 Uganda 2024-04-26 9:51:55 2027-04-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Richard Sanya Edwin
ID: UNCST-2023-R006836
 Pathways to gestational diabetes screening and diagnosis: a pilot study Identifying health system barriers and facilitators to improve care in rural Uganda.
REFNo: HS4077ES

To investigate the availability of diagnostic services, guidelines, human resources, and financing for GDM care in Kagando HDSS,To explore the knowledge, attitudes, and practices of healthcare providers in detecting and managing GDM in Kagando HDSS,To explore experiences of women with current or previous GDM in Kagando HDSS about the diagnosis and management of GDM,To determine, using facility records, the burden of GDM in primary care facilities in the Kagando Health and Demographic Surveillance System (HDSS),The main objective of this study is to identify barriers and facilitators to the diagnosis of GDM in rural Uganda.,
 Uganda 2024-04-26 9:47:15 2027-04-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Alexander Kagaha
ID: UNCST-2024-R004967
 REIMAGINING MALARIAL INFECTION CONTROL IN TERMS OF PLANETARY HEALTH BOUNDARIES
REFNo: HS4005ES

To examine the performances through which regimes of malaria and malaria control consciousness conceal and privilege specific human and nonhuman elements.,To examine the shifting terrain of consciousness on malaria control and the conditions that underpin their rise. ,To explore and examine human and nonhuman elements constituted by and within consciousness boundaries of malaria and malaria control interventions. ,To investigate the boundaries of consciousness of malaria and malaria control interventions in Uganda. The boundary of consciousness here denotes the dominant forms of collective and institutional consciousness that guides, regulates, informs and mediates malaria control.,
 Uganda 2024-04-26 9:45:31 2027-04-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
HENRY MBOWA STANLEY
ID:
SOCIAL MEDIA USAGE AND MARKET PERFORMANCE OF SMALL AND MEDIUM ENTERPRISES IN WAKISO DISTRICT, UGANDA
REFNo: SS2564ES

iv. To develop a model that will guide social media usage in order to improve the market performance of SMEs in the Wakiso district,iii. To investigate the challenges affecting social media usage by SMEs in the Wakiso district,ii. To examine the influence of social media usage on the market performance of SMEs in Wakiso district,i. To explore the various social media platforms used by SMEs in Wakiso district,The general objective of the study will be to establish the extent to which social media usage enhances market performance of SMEs in Wakiso district, Uganda.,
 Uganda 2024-04-26 9:44:07 2027-04-26 Social Science and Humanities Non-Clinical Trial Degree Award
Faisal Kiberu
ID:
Investigation Of Burnt Clay Hollow Block Reinforced Concrete Slab Under Seismic Action
REFNo: SIR327ES

Main To evaluate the seismic behavior of reinforced concrete (RC) frame with Burnt Clay Hollow Block (BC-HB) RC slab under simulated seismic action. Specific Objectives i. To determine the mechanical properties of BC-HB and all other materials that are used in BC-HB RC slab. ii. To simulate the behavior of BC-HB RC slab under seismic action. iii. To design and construct an RC frame with an optimized BC-HB RC slab. iv. To determine the performance of the optimized BC-HB RC slab under seismic action.
 Uganda 2024-04-26 9:41:58 2027-04-26 Engineering and Technology Non-Clinical Trial Degree Award
Anthony Kiwanuka N/A
ID: UNCST-2023-R005473
 MENTAL HEALTH DISORDER MANAGEMENT AND BARRIERS TO ACCESSING ITS SERVICESAMONG THE RELIGIOUS IN UGANDA
REFNo: SS2517ES

iv. To assess the coping mechanisms available for optimizing mental health disorders among the religious persons. ,iii. To analyze the barriers linked to accessing mental health services faced by the religious persons,ii. To describe mental health services and factors related to stigma associated with mental illness among the people of consecrated life.,i. To explore the ways in which mental health disorder management institutes provide access to services to persons of consecrated life. ,This study will seek to explore mental health disorder management and barriers to accessing its services among the religious in Uganda.,
 Uganda 2024-04-26 9:41:00 2027-04-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Peter Olds
ID: UNCST-2023-R006240
 Feasibility and effectiveness of atrial fibrillation detection methods among high-risk patients in southwestern Uganda
REFNo: HS3976ES

1. Compare FitBit watch with Holter monitor in detecting the burden of atrial fibrillation among high-risk patients at MRRH. We will compare FitBit watches with the gold standard of Holter monitor for detection of atrial fibrillation among high-risk patients at the MRRH outpatient cardiology clinic. We will also calculate the prevalence of atrial fibrillation in our population and build a regression model for risk factors associated with atrial fibrillation.

2. Evaluate the feasibility and acceptability of implementing atrial fibrillation detection devices in Uganda. Embedded within our non-inferiority trial, we will evaluate the feasibility and acceptability of implementing FitBit watches and Holter monitors using implementation metrics. For primary outcome, we will use the Proctor Model to assess key implementation, service, and client outcomes.

 USA 2024-04-26 9:37:51 2027-04-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Abel Bizimana
ID:
EFFECTS OF MEMBERSHIP IN SELF-HELP INGOBYI ASSOCIATIONS ON ACCESS TO MATERNAL HEALTH SERVICES IN THE CONTEXT OF ETHNICALLY MARGINALIZED BATWA IN KIGEZI, UGANDA: A MIXED METHOD STUDY
REFNo: HS4132ES

To determine how Ingobyi Associations affect access to maternal health services, To explore organisational and implementation dynamics within Ingobyi Associations, To determine factors that affect access to maternal health care services among the Batwa and other community members in the Kigezi sub-region.,To determine effects of membership in Ingobyi Associations in access to maternal healthcare services among the Batwa and other community members in the Kigezi sub-region, Uganda,
 Uganda 2024-04-26 9:33:28 2027-04-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Felix Bongomin
ID: UNCST-2020-R014224
 Undiagnosed Pulmonary Aspergillosis as a Fatal Complication of Advanced HIV Disease in Uganda: An Autopsy-Based Study
REFNo: HS3378ES

The second objective is to determine the burden of co-infections of pulmonary aspergillosis with other pulmonary infections, such as tuberculosis, histoplasmosis, cryptococcosis, and pneumocystosis, among patients with advanced HIV disease who died in selected hospitals in Northern Uganda. ,The first objective is to determine the prevalence and pattern of pulmonary aspergillosis among patients with advanced HIV disease who died in selected hospitals in Northern Uganda.,
 Uganda 2024-04-26 9:30:27 2027-04-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Samson Okello
ID: UNCST-2019-R001580
 EsophaCap for the Detection of Early Esophageal Carcinoma
REFNo: HS3248ES

Using our POC approach to carry out a diagnostic pilot study of ESCC in Uganda,In order to achieve fully automatic high-speed biomarker assaying, to design a small,light apparatus,In order to achieve a sample-to-answer assay, to implement DNA extraction, bisulfitetreatment, and methylation-specific PCR into a magnetofluidic chip with dried reagents.,Using a sponge-capsule swallowed/tethered collection device, to construct amethylation marker-based strategy to detect ESCC,To evaluate and validate the performance of the combined sponge methylation biomarker strategy in vivo in PRoBE-compliant, among prospective live cohorts od patients with EAC/HGD, ESCC and gastric cancer and controls in Uganda.,
 Uganda 2024-04-26 9:27:48 2027-04-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
David Okimait
ID: UNCST-2019-R000095
 Amref Uganda 2023 - 2030 Strategic Plan Baseline Survey
REFNo: HS3697ES

To set a benchmark for Amref Uganda’s country strategy indicators for the strategic platforms and eight strategic objectives. To carry out a stakeholder analysis of access, utilization, and provision of healthcare services as well as assessing the preparedness of health facilities for public health emergencies in Uganda. To recommend actions to improve the chances of achieving Amref Uganda's 2023-2030 strategy.
Uganda 2024-04-26 9:26:30 2027-04-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Christopher Turyatunga Bernard
ID: UNCST-2023-R006842
 Drivers, profiling and drugs resistance effects, outcomes and cost-effectiveness of diagnostic and Syndromic interventions among urogenital discharging patients in southwestern Uganda
REFNo: HS3796ES

Establish the aetiology and sensitivity profile of urogenital discharges among patients in south western Uganda. ,5. Evaluate the Comparative cost effectiveness of diagnostic and Syndromic approaches in the management of patients with urogenital discharges in south western Uganda.,4. Compare the treatment outcomes between syndromic and diagnostic approaches in the management of patients with urogenital discharges in south western Uganda.,3. Determine the drivers of drugs resistance among patients with urogenital discharges in south western Uganda. ,2. Determine the effect of drugs’ resistance on the management of patients with urogenital discharges in south western Uganda.,This study is aimed at establishing the drivers, profiling and effect of drugs resistance, comparative treatment outcomes and cost-effectiveness of diagnostic and Syndromic interventions on patients with urogenital discharges in southwestern Uganda, and it is a parallel randomized intervention at STI clinics of Kabale and Mbarara Regional Referral Hospitals and Kisiizi Mission Hospital.,
 Uganda 2024-04-26 9:21:22 2027-04-26 Medical and Health Sciences Clinical Trial Degree Award
David Kabugo
ID: UNCST-2023-R005971
 An Evaluation of the Caring for Caregiver (CFC) Intervention on caregiver emotional wellbeing, social support, and parenting stress in two rural districts of Uganda
REFNo: SS2385ES

1. To determine whether exposure to Caring for Caregiver (CFC) standardized training and supervision results in improvements in FLW counselling capacities and leads to fidelity in the application of CFC skills, tools, activities.
2. To determine whether exposure to CFC skills, tools, activities result in positive changes to emotional-wellbeing, social support and parenting stress in an intervention group relative to a comparison group.
3. To assess whether FLW emotional wellbeing, social support, and perceived stress, before, during and after training, implementation and supervision, influences caregiver and/or FLW outcomes.

 Uganda 2024-04-26 9:17:45 2027-04-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Louis Kamulegeya Henry
ID:
Assessing the role of micro-nutrient deficiency and Immune system dysfunction among HIV-positive adults with pulmonary Tuberculosis at a public health facility in Uganda.
REFNo: HS3933ES

To determine the relationship between micro and macro nutrient status with pulmonary tuberculosis treatment response (symptom improvement).,To determine the association between micro and macro nutrient status and TB specific Immune responses among HIV infected TB patients,To assess the association between macro and micro nutrient status with severity of pulmonary tuberculosis among HIV/TB infected patients,To determine the levels of macro and micro nutrients among HIV-infected pulmonary tuberculosis patients at a public health facility,To assess how nutritional status (macro and micro) among HIV-positive patients co-infected with pulmonary tuberculosis correlates with the severity of symptoms, immune response and treatment outcome at a public health facility in Uganda,
 Uganda 2024-04-26 9:15:09 2027-04-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sarah Zalwango Karen
ID: UNCST-2021-R005660
 Qualitative assessment of Facilitators and barriers to using wearable GPS watches as a device for collecting research data.
REFNo: SIR326ES

The objective is to assess the facilitators and barriers to wearing a GPS watch among individuals with no previous infection of M. tuberculosis in Kampala, Uganda. ,
 Uganda 2024-04-26 9:12:25 2027-04-26 Engineering and Technology Non-Clinical Trial Non-degree Award
Mercyline Ong'ayo Jerusa
ID:
Antecedents to participation and performance of collective action initiatives amongst the smallholder farmers in Northern Uganda
REFNo: SS2507ES

To contribute to improved performance of farmer organizations by unraveling participation dynamics in collective action initiatives undertaken by FOs in Northern Uganda., iv. To determine the influence of farmer participation and socio-economic environment on the perceived performance of CAIs.,iii. To determine the influence of farmer motivation on participation in CAIs provided by farmer organizations. ,ii. To analyze the relationship between entrepreneurial orientation and farmer participation in CAIs.,i. To determine the relationship between socio-economic environment and farmer participation intensity in CAIs provided by farmer organizations. ,
 Kenya 2024-04-26 9:09:58 2027-04-26 Social Science and Humanities Non-Clinical Trial Degree Award
Arianna Pacifico
ID:
Political Economy Analysis of Refugee Education Financing within the Context of the Inclusion Agenda
REFNo: SS2571ES

To support international donors and refugee hosting education systems achieve adequate and sustainable financing for refugee education in national systems.,
 USA 2024-04-26 9:08:09 2027-04-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Joan Atim
ID:
Prevalence of Lower Extremity Arterial Disease and Associated Factors Among HIV-infected Adults on Antiretroviral treatment at Mildmay Uganda.
REFNo: HS2912ES

ii. To determine the factors associated with lower extremity arterial disease among HIV-positive patients on ART at Mildmay Uganda.,i. To determine the prevalence of lower extremity arterial disease among HIV-positive patients on ART at Mildmay Uganda.,To determine the prevalence and factors associated with lower extremity arterial disease among HIV-positive patients on ART at Mildmay Uganda.,
 Uganda 2024-04-26 9:04:25 2027-04-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Yahaya Gavamukulya
ID: UNCST-2019-R001017
 Formulation and Pre-clinical Evaluation of Herbal Toothpaste/ Mouth Wash for Management of Oral Diseases: STI-OP Dental Solutions Project
REFNo: HS4022ES

General objective/ Purpose of the study To formulate a herbal toothpaste/ mouth wash and undertake preclinical studies on its use in management of oral diseases Specific objectives 1. To formulate herbal toothpaste/ mouth wash from extracts of selected plants for management of oral diseases. 2. To evaluate the organoleptic and physical properties of the formulated herbal toothpaste / mouth wash as per specified standards. 3. To evaluate the antimicrobial activity of the formulated herbal remedy against selected oral pathogens, Streptococcus mutans and Staphylococcus aureus. 4. To produce one batch of the fully tested herbal remedy for subsequent field testing.
Uganda 2024-04-22 6:35:14 2027-04-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Michael Okot
ID: UNCST-2023-R005793
 FACTORS INFLUENCING ACCESS AND UTILISATION OF ELIMINATION OF MOTHER TO CHILD TRASMISSION (EMTCT) OF HIV SERVICES IN ACHOLI SUB REGION, UGANDA.
REFNo: HS3996ES

To determine the enabling factors affecting access and utilization of the EMTCT services by the pregnant and breastfeeding women in Acholi Sub Region, Uganda.,To identify the predisposing factors affecting access and utilization of the EMTCT services by the pregnant and breastfeeding women in Acholi Sub Region, Uganda.,To explore and analyses the factors influencing the access and utilisation of the EMTCT services by pregnant women including those in high-risk groups in Acholi Sub Region.,
 Uganda 2024-04-22 6:25:27 2027-04-22 Medical and Health Sciences Non-Clinical Trial Degree Award
Justine  Komunyena Tumusiime
ID: UNCST-2023-R008465
 STAKEHOLDER ACCEPTABILITY AND USABILITY OF A MICROARRAY PATCH FOR PEDIATRIC ANTIRETROVIRAL TREATMENT IN UGANDA
REFNo: HS3928ES

To observe and interview stakeholders who would be potential users of the pediatric ARV MAP in Uganda
 Uganda 2024-04-22 6:21:28 2027-04-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Fred Ssewamala
ID: UNCST-2020-R014060
 Bridges2Scale: Testing Implementation Strategies for an intervention among young people affected by AIDS
REFNo: SS2488ES

Bridges2Scale will use a two-arm Hybrid III effectiveness-implementation cluster randomized clinical trial, where we will compare two multifaceted strategies (standard vs. enhanced) for scaling the Bridges interventions (consisting of financial literacy training, peer mentorship, family income-generating , and youth development accounts). The standard implementation strategy has been applied in our prior and ongoing studies and involves educational meetings that prepare staff members to deliver Bridges with minimal disruption to site workflow. This will be compared to an enhanced strategy that will be developed using Implementation Mapping, a systematic protocol for developing implementation strategies using theory, evidence, and stakeholder input. Aim 1: Compare the implementation effectiveness of the standard implementation strategy vs. an enhanced implementation strategy. Aim 2: Determine the clinical effectiveness of Bridges implemented via a standard vs. enhanced implementation strategy. Aim 3: Explore implementation processes, mechanisms, and determinants. Aim 4: Compare the cost and cost-effectiveness of the two implementation strategies.
 Uganda 2024-04-19 18:42:54 2027-04-19 Social Science and Humanities Clinical Trial Non-degree Award
Margaux Dupuis
ID:
Assessing the Role of Maternal Social Network Inheritance in the Social Integration of Juvenile Vervet Monkeys (Chlorocebus pygerythrus)
REFNo: NS802ES

I aim to answer the questions: how do maternal dominance rank, age, social network position, and mother-offspring proximity relate to the proximity and grooming networks of their juveniles? Does this differ by offspring sex and/or age?
I hypothesized that maternal social network inheritance occurs and differs by sex and age in vervet monkeys because of (1) mother-offspring proximity, (2) influences of maternal dominance rank and age, (3) patterns of youngest ascendency of female dominance rank in vervets, and (4) female philopatry.
 France 2024-04-19 18:38:19 2027-04-19 Natural Sciences Non-Clinical Trial Degree Award
Rhona Mijumbi M
ID: UNCST-2023-R006843
 Regional Hub for Knowledge Translation and Evidence-Informed and Equity-Centred Policymaking in Africa
REFNo: SS2454ES

To assess the impact of cross-country co-created evidence products on the policy making process in the individual countries affected by the same policy challenge,To assess the impact of participation in the regional hub on the development and pilot of new strategies for EIDM,To assess the context specific factors that impact success of a regional hub to support peer-to-peer learning and co-creation in EIDM,To assess the different institutions’ readiness to collaborate in a regional hub to foster cross-institutional peer-to-peer learning for EIDM,To study the impact of a regional hub designed to facilitate cross-institutional peer-to-peer learning on innovative strategies aimed at bolstering evidence-to-policy in priority SDGs in Uganda, Tanzania, Ethiopia, and Malawi. The priority SDGs we shall use for this study are reproductive health and clean energy.,
 Uganda 2024-04-19 18:36:13 2027-04-19 Social Science and Humanities Non-Clinical Trial Non-degree Award
Godfrey Ejuu
ID: UNCST-2021-R013978
 PLAYFUL FUTURES: A RANDOMIZED CONTROL TRIAL OF EARLY CHILDHOOD CARE AND EDUCATION TEACHER TRAINING AND MENTORSHIP IN UGANDA
REFNo: SS1634ES

Overall aim and outcome
The overall goal of the project is “Children improve literacy, numeracy skills and develop socio emotional skills through Learning through Play.
Main research question
To what extent does the ECCE intervention improve quality and sustained learning through play and holistic development among children 3-6 years in centre based learning environments?

Specific research questions
Aim one: To improve quality of the ECCE learning environment for children three-to-six years old
Research questions:
• What is the effect of the LtP intervention on teaching practices, learning environment and development of holistic skills of children three-to-six years from ECCE centers? Is there a difference in outcomes between boys and girls?
Aim two: To improve educators’ instructional practice and implement Learning through Play activities
Research questions:
• What is the effect of LtP mentorship on pedagogical skills in ECCE classrooms? Does this differ by sex of educators?
• What is the effect of the Playful Futures LtP intervention package on pedagogical skills in ECCE classrooms?
Aim three: Coordinating Centre Tutors (CCTs) provide useful, recurrent and effective guidance to educators on LtP
Research questions:
• To what extent does Playful Futures intervention encourage effective and regular mentorship to ECCE educators in support of LtP?
Aim four: Key stakeholders have improved knowledge, attitudes and practices, and abilities to introduce and promote learning through play, including educators, parents, government officials, and community leaders
Research questions:

Research questions:
• What is the effect of playful futures intervention in improving attitudes and practices of parents and community members regarding LtP?
• How does Playful Futures influence parents’ involvement on play activities at home?

 Uganda 2024-04-19 18:24:07 2027-04-19 Social Science and Humanities Non-Clinical Trial Non-degree Award
ABRAHAM OGWAL
ID: UNCST-2020-R014262
 Thermo-Physical Characterization of Briquettes from Maize cobs and Rice husks in Kole District, Northern Uganda
REFNo: NS457ES

(i). To determine proximate composition of briquette samples produced from blended maize cobs and rice husks.
(ii). To evaluate the efficiency of briquette samples produced from blended maize cobs and rice husks.
(iii). To determine gaseous and black carbon emissions level of briquette samples blended from maize cobs and rice husks.

Uganda 2024-04-19 18:10:37 2027-04-19 Natural Sciences Non-Clinical Trial Degree Award
HENRY KATAMBA STANLEY
ID: UNCST-2024-R004704
 A model to improve the adoption, utilisation and sustainability of digital health initiatives by health workers in Uganda.
REFNo: HS4013ES

The purpose of this study will be to investigate the factors that are barriers to improve performance of electronic health management information systems despite adoption of digital health initiatives in health facilities at Uganda and to develop an integrated support model to improve the adoption and sustainability in the utilisation of digital health initiatives and to strengthen performance of electronic health management information systems by health workers in health facilities at Uganda. ,
 Uganda 2024-04-18 13:34:22 2027-04-18 Medical and Health Sciences Non-Clinical Trial Degree Award
Baker  Lukwago
ID:
Optimizing Journey Mapping Techniques: Innovating Methods to Better Understand Pregnancy Journeys for Women Living in Uganda Version 1.2 February 2024
REFNo: HS4024ES

 Objective 2.b: Document women’s experience (satisfaction/dissatisfaction) with digital engagement touchpoints along the pregnancy care-seeking decision pathway, noting differences between urban and rural settings. , Objective 2.a: Determine the potential of remote data collection to capture key pregnancy care-seeking decisions, (attendance of ANC, referral for conditions/ complications, and childbirth experience) including barriers, facilitators and influencers at decision-making point, noting differences between urban and rural settings; gather data on health expenditure at each pregnancy care-seeking pathway point; and capturing quality of maternal care and client experience data,Phase 2- Objective 1: Investigate how remote engagement mechanisms can be used to collect consumer insights more frequently (relative to traditional journey mapping), Objective 1.c: Explore women’s preferences for future digital engagement touchpoints along the pregnancy care-seeking and primary care decision pathway, noting differences between urban and rural settings., Objective 1.b: Describe the quality of maternal care and client experience, disaggregated by urban and rural settings., Objective 1.a: Describe key pregnancy care-seeking decisions, (attendance of ANC, referral for conditions and complications, childbirth experience, follow-up health visits in the post-partum period) including barriers, facilitators, and influencers at decision-making points, noting differences between urban and rural settings and previous pregnancy care experience. ,Phase 1-Objective 1: Use traditional journey mapping techniques to describe the pregnancy care-seeking pathway of women who gave birth in urban and rural settings of Uganda ,
 Uganda 2024-04-18 13:27:52 2027-04-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Doreen Nakimuli
ID: UNCST-2021-R013668
 Evaluation for Maverick Next Project on Male Engagement in Contraceptive Use in Uganda: Wakiso District
REFNo: SS2511ES

3. To understand couple practices and perceptions about couple communication on contraception and family size,2. To monitor perception and practices of men towards modern contraception and partner support to access these services.,1. To understand Knowledge and attitude towards modern contraceptives among men in the pilot areas.,
 Uganda 2024-04-18 13:21:59 2027-04-18 Social Science and Humanities Non-Clinical Trial Non-degree Award
EVYLINE ISINGOMA BARUGAHARA
ID: UNCST-2024-R005434
 EFFICACY OF PERSEA AMERICANA AND HIBISCUS SABDARIFFA CALYX, SEEDS AND LEAVES IN MANAGEMENT OF NUTRITIONAL ANAEMIA USING A MOUSE MODEL.
REFNo: HS3779ES

1. To analyse the nutrient composition of Persea Americana leaves and seeds and Hibiscus Sabdariffa leaves and calyx.
2. To determine the bioavailability of iron in Persea Americana leaves and seeds and Hibiscus sabdariffa leaves and calyx.
3. To assess the phytochemical compounds in Persea Americana leaves and seeds and Hibiscus Sabdariffa leaves and calyx.
4. To assess the impact of feeding on Persea Americana leaves and seeds and Hibiscus Sabdariffa leaves and calyx on the haemoglobin, transferrin saturation and serum ferritin levels using a mouse model.
 Uganda 2024-04-18 13:12:46 2027-04-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
CHRISTINE  KARUNGI
ID:
Barriers and facilitators to uptake and utilization of the Mental Health Gap Action Programme Intervention Guide (mhGAP-IG) for dementia assessment and management by non-specialist healthcare providers in rural southwestern Uganda: A case study of Kabale District
REFNo: HS3949ES

1. To characterize the barriers and facilitators to utilization of the mhGAP-IG 2.0 for dementia assessment and management by non-specialist healthcare providers in Kabale district 2. To pilot test and evaluate the feasibility of implementing the mhGAP-IG 2.0 for dementia assessment and management by non-specialist healthcare providers in Kabale district 3. To co-design a culturally tailored implementation strategy to enhance adoption of the mhGAP-IG 2.0 for dementia assessment and management by non-specialist healthcare providers in Kabale district
Uganda 2024-04-18 13:07:40 2027-04-18 Medical and Health Sciences Non-Clinical Trial Degree Award
Emmanuel  Arinaitwe
ID: UNCST-2021-R011754
 The transmission of artemisinin resistant parasites before and after conventional artemisinin-combination therapy: a longitudinal study
REFNo: HS3716ES

The main objective of the proposed research is to quantify the transmissibility of artemisinin-sensitive and artemisinin- resistant parasite to mosquitoes before and after drug pressure. Secondary objectives include the assessment of drug sensitivity by ex vivo Ringstage Survival Assay (RSA) and parasite clearance following treatment, as will be assessed by microscopy.
 Uganda 2024-04-18 12:57:57 2027-04-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Titus Owing Achika
ID: UNCST-2023-R007102
 UTILISATION OF ICT AND PROPHETIC WITNESS IN SELECTED RELIGIOUS FOUNDED SECONDARY SCHOOLS IN UGANDA
REFNo: SS2300ES

This main study's objective is to analyse how staff in Catholic religious founded schools are harnessing the power of ICT to mould the character of their students. Specifically, this study intends:,To identify strategies of improving ICT use for character formation of students and staff,To find out the challenges teaching staff and students faced in using ICT to promote moral values,To analyses how students use ICT to promote love, compassion and respect for others as a means of witnessing Christ.,To establish how administrators and teaching staff use ICT to promote moral values among learners ,
 Uganda 2024-04-17 18:44:27 2027-04-17 Social Science and Humanities Non-Clinical Trial Non-degree Award
samson katumba
ID: UNCST-2023-R005614
 Managerial Performance of Mulago National Referral Hospital in Uganda, in the Lenses of a System's Perspective
REFNo: SS2213ES

General Objective
The main objective of the study is to assess the extent to which managerial contribution on a yardstick of internal organizational factors influences the effective performance of Mulago National Referral Hospital.
Specific Objectives
The specific objectives of the study are as follows:
1. To analyse how managerial innovations determine the effective administration of medical supplies/items used in Mulago National Referral Hospital.
2. To explain how the managerial work methods adopted determine an effective precision of operations at Mulago National Referral Hospital.
3. To analyse how managerial strategies adopted determine the adequacy of resources to service Mulago National Referral Hospital.
4. To explain how managerial decisions determine the effectiveness of Mulago National Referral Hospital policies adopted by the hospital.
Uganda 2024-04-17 18:40:49 2027-04-17 Social Science and Humanities Non-Clinical Trial Degree Award
Ruth Nsibirano
ID: UNCST-2022-R009062
 GENDER AND DIGITALIZATION ACROSS CONTEXT (GENDIG)” Enhancing the Understanding and Application of Gender Studies for Sustainable Quality Higher Education and Community Development Research
REFNo: SS1643ES

Overall objective:
To integrate an alternative digital mode of delivery by digitalizing the MA Gender Studies Curriculum and enhance supervision by integrating online supervision.

Specific Program Objectives will include:
1. Digitalize existing courses so that there will be a fully-fledged online MA (Gender Studies) program to concurrently run with the physical MA, Gender Studies Program. (Since the UiA does not have a fully-fledged MA Gender studies program, interested learners from Norway can be encouraged to enroll on the Digitalized MA Gender Studies Program at Makerere University and the same is true for UDSM). (Work Package 1).


2. Develop a joint online MA (Gender Studies) course of GS 7205: Gender and Development Management offered at Mak, with the UiA Development Management Course. The two universities then can thereafter continue to offer this course to students. There will be an opportunity for: student and staff mobility, transfer of credits, joint student and staff research and joint supervision. (Work Package 2).

3. Strengthen collaboration with stakeholders so that efforts of promoting gender equality can be felt in the community. (Through collaboration with and mutual capacity building, short term courses will be developed to meet the needs of the civil society, graduate students will work with civil society to enrich the theory with practice - NGOs and private actors with the aim of enriching community understanding and application of gender knowledge, concepts and good gender practices for development). (Work Package 3).

4. Plan for interaction across programs and contexts (understanding gender relations as contextual and influenced by culture) This will be a pillar in the collaborative –comparative research and publication, as well as action research. Both staff and students in UiA, UDSM and Mak will undertake research under themes. It will contribute to knowledge production on gender relations, gendered experiences across context (Work Package 4)

 Uganda 2024-04-17 18:37:33 2027-04-17 Social Science and Humanities Non-Clinical Trial Non-degree Award
JOSAPHAT KAYOGOZA BYAMUGISHA
ID: UNCST-2019-R001680
 Community survey on the effect of access to water on the maternal and child health of Mutugunda Population
REFNo: HS3505ES

To survey the effect of access to water and women empowerment on maternal and child health of Mutugunda Population,To explore the role of the NCENT group as a potential avenue to improve maternal and child health outcomes.,To describe the impact of water tanks on maternal and child health and community health in Mutugunda,To describe the access and use of maternal and child health services by women and children living in Mutugunda,
 Uganda 2024-04-17 18:30:39 2027-04-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jenifer Atala
ID: UNCST-2021-R012617
 Uptake and implementation of new secondary prophylaxis recommendations for high risk Rheumatic Heart Disease patients: A cross sectional study in Uganda and a Global perspective
REFNo: HS3805ES

III. To determine the current practice in implementation of the AHA presidential advisory recommendations on secondary prophylaxis for RHD patients among expert clinicians in RHD care around the world. ,II. To assess the perception of RHD patients about being switched to oral antibiotic prophylaxis,I. To determine the proportion of those with high-risk RHD disease switched to oral antibiotic prophylaxis,To determine the uptake of new secondary prophylaxis recommendations and its implementation in high risk RHD patients,
 Uganda 2024-04-17 18:22:40 2027-04-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
BYAMUGISHA EDISON
ID:
RETENTION LEVEL AND ASSOCIATED FACTORS AMONG COMMUNITY HEALTH WORKERS IN MBARARA, RUBIRIZI AND RWAMPARA DISTRICTS: A 15-19 YEAR FOLLOW UP STUDY RefNo: MUST-2023-1183
REFNo: SS2542ES

1. To determine the level of retention of Community Health Workers in Mbarara, Rubirizi and Rwampara Districts after 15 -19 years. 2. To establish factors associated with retention among Community Health Workers in Mbarara, Rubirizi and Rwampara Districts after 15 -19 years
Uganda 2024-04-16 9:15:32 2027-04-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
BYAMUGISHA EDISON
ID:
LIVED EXPERIENCES OF LONG-SERVING (>15 YEARS) COMMUNITY HEALTH WORKERS IN MBARARA, RUBIRIZI AND RWAMPARA DISTRICTS. A PHENOMENOLOGICAL STUDY Ref No: MUST 2023-1294
REFNo: SS2538ES

To discover the copying strategies utilized by long-serving (>15 years) Community Health Workers in persisting for their volunteer roles and responsibilities in Mbarara, Rubirizi and Rwampara Districts.,To identify challenges faced by long-serving (>15 years) Community Health Workers when carrying out their roles and responsibilities in Mbarara, Rubirizi and Rwampara Districts.,To explore the motivational factors enabling sustained engagement among long-serving (>15 years) Community Health Workers in Mbarara, Rubirizi and Rwampara Districts,To explore the lived experience of long-serving (>15 years) Community Health Workers regarding their motivations, challenges and coping strategies in carrying out their roles and responsibilities in Mbarara, Rubirizi and Rwampara Districts,
 Uganda 2024-04-16 9:10:48 2027-04-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
James Kiwanuka-Tondo
ID:
Olutindo (loosely translated “THE BRIDGE”): Promoting Sexual and Reproductive Health Behavior Change among Teenage Girls in Mukono district, through Strategic Communication intervention
REFNo: SS2529ES

The aim of this study is to design a strategic communication intervention to promote effective sexual and reproductive health behavior change,What communication strategies can be used to reduce teenage pregnancies in Mukono District,What specific factors lead to high teenage pregnancies in Mukono District? ,What are the perceptions and attitudes of the teenage girls about the causes of teenage pregnancy in Mukono District? ,
 Uganda 2024-04-16 9:03:57 2027-04-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
Robert MPIIRA
ID: UNCST-2022-R005391
 Economic and Environmental Impacts of Infrastructure Improvement in Kampala and Land Acquisition Frictions
REFNo: SS2510ES

Understand how the frictions and their potential heterogeneity may alter the equilibrium location of infrastructure in Kampala, and what the economic and welfare costs of these frictions are,3. Identify the frictions that hinder the acquisition of the Right of Way for the construction of infrastructure in Kampala and assess whether these frictions are heterogeneous over space,2. Quantify the impact of road improvements in Kampala in terms of (i) changes in land and property value, (ii) changes in air quality and (iii) changes in flood risk,1. Investigate the role of economic market failures and other economic mechanisms in affecting the government’s ability to acquire the land needed to build infrastructures.,
 Uganda 2024-04-16 8:57:43 2027-04-16 Social Science and Humanities Non-Clinical Trial Degree Award
Douglas Bulafu
ID: UNCST-2021-R011774
 Strengthening Death Notification and Reporting in Kalangala and Buvuma Districts in Uganda
REFNo: HS3966ES

To explore the status of death notification and registration and implement a capacity building intervention to strengthen mortality surveillance systems at health facility and community levels in Buvuma and Kalangala Districts ,6. To strengthen the technical capacity of facility health workers and community health workers to notify and report deaths that occur in health facilities and communities. ,5. To improve the knowledge and awareness of death notification and reporting among facility and community health workers as well as community leaders.,4. To explore the barriers of death notification and reporting among facility and community health workers as well as community leaders. ,3. To explore the facilitators of death notification and reporting among facility and community health workers as well as community leaders. ,2. To explore the individual experiences of community members regarding death notification and reporting in Buvuma and Kalangala districts,1. To describe the process of death notification and reporting among facility and community health workers in Buvuma and Kalangala districts. ,
 Uganda 2024-04-16 8:53:03 2027-04-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Fiona Atim -
ID: UNCST-2020-R015040
 Implementation of Community Engagement In Community-Based Health Research In Uganda: Gatekeepers Perceptions
REFNo: HS3951ES

To evaluate the different proposed community engagement mechanisms,To explore the understanding of gatekeepers on existing national guidelines and frameworks for community engagement,To explore the understanding of gatekeepers and their roles on research and community engagement,To explore the perceptions of gatekeepers towards community engagement during implementation of community-based research in Uganda?,
 Uganda 2024-04-16 8:42:46 2027-04-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jessica Reemeyer Elizabeth
ID:
Capturing hypoxia avoidance behaviour in wild fish with open-source camera traps
REFNo: NS776ES

The main goal of this project is to document fish behavioural responses to low oxygen in the field using underwater camera traps.
Canada 2024-04-16 8:37:19 2027-04-16 Natural Sciences Non-Clinical Trial Degree Award
Peter Mukasa Kivunike
ID:
Understanding readiness, barriers and facilitators for effective coverage for obstetric fistula surgery and care in central eastern (Busoga) region of Uganda REF NO: UCUREC-2023-458
REFNo: HS2732ES

4. To estimate the effective coverage for Obstetric fistula surgery and care services in central eastern (Busoga) region of Uganda. ,3. Measure the structural, process and outcome quality of care for obstetric fistula surgery and care in 2 tertiary hospitals in eastern Busoga region. ,2. Explore service provider perspectives on the barriers and facilitators for effective obstetric fistula surgery and care services. ,1. Assess surgical readiness and output for obstetric fistula surgery in the regional referral hospital and general hospitals in central eastern (Busoga) region ,The overall aim of the study is to examine readiness, quality, barriers, facilitators and estimate effective coverage for obstetric fistula surgery and care in central eastern (Busoga) region of Uganda,
 Uganda 2024-04-16 8:36:07 2027-04-16 Medical and Health Sciences Non-Clinical Trial Degree Award
Joseph Hokello Francis
ID: UNCST-2023-R007565
 Bioprospecting for HIV-1 latency reversing agent (prostratin) from indigenous medicinal plants for latency reversal in HIV-1 subtypes A and D in Uganda (HIV-1_AD_LRA study)
REFNo: HS3600ES

4. To evaluate the safety and ex vivo efficacy of the formulated natural products for HIV latency reversal. ,3. To formulate and standardize the preparation procedure of the investigational natural products used in management of HIV/AIDS.,2. To analyze the phytochemical composition of the selected medicinal plants used in management of HIV/AIDS.,1. To conduct an ethnobotanical survey for selected medicinal plants used in management of HIV/AIDS by selected Traditional Medical Practitioners.,General Objective To generate credible and reliable scientific evidence about selected medicinal plants used in management of HIV/AIDS for formulation of standardized products for reversal of HIV latency in HIV-1 subtypes A and D in Uganda. ,
 Uganda 2024-04-16 11:46:58 2027-04-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Felicitas Egunyu
ID:
Mining impacts and non-government organizations in Uganda
REFNo: SS2459ES

To investigate the roles of NGOs in alleviating the social impacts of artisanal gold mining in Busia and Mubende Districts, Uganda.,Develop a typology of NGOs implementing projects to alleviate the social impacts of ASGM in mining host communities.,Explore the impact of the NGO-activities implemented to alleviate the social impacts of ASGM in the host communities.,Describe the activities implemented by NGOs to alleviate the social impacts of ASGM in host communities.,Examine roles of NGOs in alleviation of the social impacts of ASGM in the host communities.,1. Identify who is engaged in ASGM as well as who loses and benefits and how in host communities in Busia and Mubende districts in Uganda. ,
 Uganda 2024-04-15 11:59:06 2027-04-15 Social Science and Humanities Non-Clinical Trial Non-degree Award
Cissy  Kityo
ID: UNCST-2021-R013663
 The training needs assessment for research training in cell and gene therapy for HIV in Uganda. TNA study
REFNo: HS3893ES

1. To educate the research participants/communities about the benefits of conducting the training needs assessment for research training in cell and gene therapy (C>) for HIV in Uganda.
2. To inform the research participants and key stakeholders about upcoming exercise on training needs assessment for research training in C> for HIV in Uganda and how they should be involved.
3. To establish and/ or strengthen existing partnerships with key stakeholders critical to the successful conduct of the training needs assessment for research training in C> for HIV in Uganda.
4. To guide on mobilization, recruitment, and retention of study Participant for the conducting the training needs assessment for research training in C> for HIV in Uganda.
5. Explain the Inclusion Criteria and Exclusion Criteria for respondents.
6. Different scientist who at participating shall be requested to provide or advise on how to get the relevant materials

Uganda 2024-04-12 7:33:14 2027-04-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Abel Nzabona
ID:
Institutional resilience and recovery from disasters and pandemics in selected districts of rural Uganda-exploring the implications for governance and public policy implementation
REFNo: SS2544ES

1. To provide a holistic picture of rural local government in the countries targeted by this project.
2. To provide an analysis of the resilience and sustainability of rural livelihoods.
3. To provide an analysis of governance processes and policy implementation systems for rural livelihoods in the two countries.

 Uganda 2024-04-12 7:26:29 2027-04-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jane  Kabami
ID: UNCST-2021-R012588
 Community-based, peer-delivered PrEP for female sex workers in rural Uganda: The Peers for PrEP (P4P) Phase B Study
REFNo: HS3869ES

To assess the feasibility, acceptability, and preliminary effectiveness of a community-based, peer-delivered PrEP intervention for women engaged in sex work in rural Uganda
 Uganda 2024-04-12 7:20:06 2027-04-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JOSEPH MUYIIRA
ID:
TOTEMS PRACTICE AND WILDLIFE CONSERVATION IN BUGANDA KINGDOM, UGANDA. ACASE OF SELECTED CLANS OF BUGANDA KINGDOM.
REFNo: NS755ES

I. To determine the influence of totems’ practice on wildlife conservation among inhabitants of Buganda Kingdom. II. To assess the effect of plant and animal totems on conservation of wildlife resources in Buganda Kingdom. III. To ascertain the constraints facing the conservation of totems in Buganda Kingdom. IV. To suggest strategies for promoting wildlife conservation in Buganda Kingdom.,
 Uganda 2024-04-12 7:14:16 2027-04-12 Natural Sciences Non-Clinical Trial Degree Award
Catherine Hobaiter
ID: UNCST-2019-R001480
 Behavioural Syntactics: the emergence of chimpanzee gestural capacities through adaptations for locomotion, sleep, and social co-ordination.
REFNo: NS735ES

Hypothesis 1: climbing and nest building shaped chimpanzees’ bodies and minds in ways that were later exapted for their unique gestural communication.
Prediction 1a) The rapid expansion in the great ape gestural repertoire was founded on a greater range of available movement selected for in climbing/nest building.
a. If so, then we should see the use of specific hand/arm movements in climbing and nest building that are available to great apes, but not small apes and other primates
b. If so, then we should see those movements present in great ape gestures
Prediction 1b) The basic ability to plan a sequence of actions, with hierarchically structured sections, emerged in the (relatively) simple behaviour of climbing and nest building, and was subsequently exapted/refined for food processing and then communication.
a. If so, then nest building and climbing should show sequences of motor actions that are planned from start to finish with recurred/recursive sections within them
b. If so, then we would see flexible programs of motor actions adapted to the task from the outset.

Hypothesis 2: rhythmic patterning and co-ordination of social behaviour provides a mechanism for social cohesion in chimpanzees.
Prediction 2a) The rhythm and patterning of social touch in chimpanzee grooming will show overlap with the stroke patterns that promote oxytocin release in human social touch.
Prediction 2b) Chimpanzees will show increased co-ordination in locomotory activities (e.g., walking and climbing) when engaged in activities where social cohesion is beneficial (e.g., patrolling).
 UK 2024-04-12 7:07:57 2027-04-12 Natural Sciences Non-Clinical Trial Non-degree Award
Gimono Esther Munira Ali
ID:
Assessment of sexual and reproductive health rights of Deaf women and Deaf adolescent girls in Uganda. Mbale district.
REFNo: SS2222ES

1. To establish the lived experiences of Deaf women and deaf adolescent’s girls on sexual reproductive health rights in Mbale District, Uganda.
2. To analyse the challenges facing Deaf women and deaf girls on sexual reproductive health rights in Mbale District, Uganda.
3. To establish the contribution of government and as a duty bearer in terms of implementing sexual reproductive health rights of Deaf women and deaf girls in Mbale District.
 Uganda 2024-04-12 6:58:27 2027-04-12 Social Science and Humanities Non-Clinical Trial Degree Award
Samson kaboko Benon
ID:
Rising through the Poverty Ceiling to Executive Leadership in Central Uganda
REFNo: SS2379ES

1. To find out the dominant themes expressed by those reared in poverty to describe their lived experiences of rising to the upper echelons of executive leadership in Central Uganda.
2. To explore the perceived negative influences of experiencing poverty while growing up on the rise to the upper echelons of executive leadership in Central Uganda.
3. To find out the perceived positive influences of experiencing poverty while growing up on the rise to the upper echelons of executive leadership in Central Uganda.
4. To find out the other lived experiences other than escaping from the effects of poverty that contributed to the rise to executive leadership in Central Uganda.

 Uganda 2024-04-12 6:46:17 2027-04-12 Social Science and Humanities Non-Clinical Trial Degree Award
Waruiru Kolff Kayla Tinie
ID: UNCST-2021-R012291
 Pan prescription: Medical behaviour and cognition
REFNo: NS784ES

Investigate (i) which behaviours of the Ngogo community use to treat wounds and (ii) whether humans and chimpanzees share features of medical cogntion and prosociality.
 Netherlands 2024-04-09 18:44:03 2027-04-09 Natural Sciences Non-Clinical Trial Degree Award
Lawrence  Egulu
ID:
Giving voice to the victims of the insurgency in Eastern Uganda in the late 1980s and early 1990s: A Phenomenological Research Study
REFNo: SS2498ES

• To document the survival, coping and recovery strategies that the victims adopted in regard to the experiences they underwent, • To record the kind of support the victims received from the local, national or international communities, • To document how the victims made meaning of the experiences they underwent, • To explore the lived experiences of the victims of the insurgency,
 Uganda 2024-04-09 18:41:49 2027-04-09 Social Science and Humanities Non-Clinical Trial Degree Award
Veronica Groves Kelly
ID:
The response to predation cues from an invasive predator in fish with different histories of interactions or hypoxia tolerances.
REFNo: NS779ES

To understand how abiotic environmental stressors and invasive predator pressure impact the behaviour and physiology of freshwater fishes.
Canada 2024-04-09 18:39:14 2027-04-09 Natural Sciences Non-Clinical Trial Degree Award
John Barugahare
ID:
ETHICALITY OF PRESUMED CONSENT AND SOCIAL SUPPORT FOR THE CADAVERIC ORGAN DONATION AND TRANSPLANT SYSTEM IN UGANDA: A PILOT STUDY OF KCCA AREA
REFNo: HS3945ES

The goal of the study is ‘to generate evidence that will inform the development of additional ethical and socially appropriate measures in the implementation of Uganda’s Human Organ Donation and Transplant Act, 2022, to build and maintain public trust and support for organ donation and transplant services in Uganda’.
Specific objectives
i. To assess the knowledge of boda boda riders, regular boda boda transport users and their next of kin, in KCCA area about the existing law on consent for cadaveric organ donation in the Uganda Human Organ Donation and Transplant Act 2022.
ii. To examine attitudes (willingness and unwillingness) towards presumed consent for cadaveric organ procurement among boda-boda riders, regular boda boda transport users and their next of kin in Kampala Capital City Authority area.
iii. To analyze public perspectives on strategies for improving public trust in the implementation of the organ donation and Transplant system in Uganda

 Uganda 2024-04-09 18:36:37 2027-04-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
SAMANYA  BULHAN
ID:
Decentralization and Service Quality in Healthcare sector of Uganda : A Case of Busoga Sub-Region
REFNo: SS2490ES

5.To validate the inter-district healthcare model of Busoga sub-region. ,3.To design an inter-district healthcare model to improve on service quality in Busoga Sub-region . ,2.To examine the differences in service quality provision among the district hospitals in Busoga Sub-region .,1.To investigate the theoretical implication on decentralization and service quality in healthcare sector of Busoga Sub-region. ,The purpose of the study is to evaluate Decentralization and Service Quality in health care sector of Uganda a case of Busoga Sub-Region. ,
 United Kingdom 2024-04-09 18:33:53 2027-04-09 Social Science and Humanities Non-Clinical Trial Degree Award
Eve  Namisango
ID: UNCST-2021-R014038
 Integration of child- and family-centred outcome measurement into routine palliative care to drive person-centredness and quality in Uganda.
REFNo: HS3578ES

1) To develop a child expert group to advise and act as peer promoters.
2) To refine C-POS for implementation across age groups and diagnoses.
3) To develop a quality improvement team within each of our three demonstration sites and
identify site-specific integration plans.
4) To develop a Decision Support Tool (DST) specifying appropriate and feasible clinical
responses to real-time data that are feasible and effective within local resources.
5) To implement C-POS for quality improvement cycles within routine practice in three
demonstration sites.
6) To determine stakeholder views on quality improvement mechanisms and impact.
7) To develop an implementation manual with consortium partners for the region.
Uganda 2024-04-09 18:21:39 2027-04-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Christine Ampumuza
ID: UNCST-2023-R007425
 Modelling Domestic Tourism on Demand and Supply Factors in Uganda RefNo:
REFNo: SS2489ES

iv. To examine the impact of demand and supply factors on domestic tourism consumption in Uganda using econometrics models.,iii. To determine the demand factors influencing domestic tourism consumption in Uganda.,ii. To identify the supply factors influencing domestic tourism consumption in Uganda.,i. To assess the current status of domestic tourism in Uganda.,To identify the supply and demand factors that influence domestic tourism and to develop a model for its promotion in Uganda. ,
 Uganda 2024-04-09 18:13:48 2027-04-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ismael Ddumba-Nyanzi Elisha
ID: UNCST-2024-R005106
 Evaluation of the Kulea Watoto Project
REFNo: SS2474ES

1. Evaluate the effect of the Kulea Watoto (KW) Project on the following outcomes:
a) Early learning
b) Responsive caregiving knowledge and practices of parents and caregivers.
c) Household economic well-being
d) Child health and development
e) Psychosocial health and well-being of the child and primary caregiver
2. Qualitatively assess the pathways/mechanisms for impact, satisfaction, and the perceived usefulness of the individual components on well-being of children and caregivers. Further, it seeks to understand continuously the implementation feasibility of the intervention components.

Uganda 2024-04-04 8:29:45 2027-04-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
Patricia NAHIRYA Ntege Nahirya
ID: UNCST-2019-R001117
 Long-Term Follow-Up of CAB LA for Participants in HPTN 083 and HPTN 084 CAB PrEP Studies at Risk of HIV Acquisition.
REFNo: HS3876ES

Primary Objective
• To describe new HIV infections in adult and adolescent participants at risk of HIV acquisition included in the HPTN 084 studies and their associated sub-studies.

Secondary Objective
• To describe any serious adverse events (SAEs), Grade 3 and Grade 4 ISRs, and AEs leading to withdrawal in adult and adolescent participants included in the HPTN 084 studies and their associated sub-studies.


 Uganda 2024-04-04 8:20:33 2027-04-04 Medical and Health Sciences Clinical Trial Non-degree Award
Firminus  Mugumya
ID:
FORMATIVE RESEARCH ON EARLY CHILDHOOD DEVELOPMENT IN NAKIVAALE REFUGEE SETTLEMENT
REFNo: SS2041ES

The overall aim of the implementation research study is to co-design, implement and evaluate an innovative integrated ECD intervention that promotes positive outcomes for refugee children in Nakivaale refugee settlement. This study protocol outlines the formative research to support the development of the intervention, The specific objectives of the formative research are as follows:

1. To describe the current developmental status of children (0-5) in Nakivaale refugee settlement
2. To map formal and informal ECD services in the Nakivaale refugee settlement
3. To understand the current caregiving knowledge, attitudes and practices, in the five domains of the nurturing care framework in the refugee and host setting of Nakivaale refugee settlement;
4. The understand the enabling and influencing factors and barriers to ECD service provision and caregiving among service providers and caregivers

 Uganda 2024-04-04 8:07:24 2027-04-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
Joseph Kiva S.
ID:
Exploring the role of participatory communication in the promotion of maternal health care programmes: A case study of 89.2 Central Broadcasting Services FM in Uganda.
REFNo: SS2231ES

4. To find out in what ways has the programme facilitated community dialogue in the promotion of maternal health among pregnant women and mothers.,3. To explore the pregnant women/mothers’ perceptions of the participatorycommunication channels used during the health programme,2. To explore the participatory communication approaches used in the health programme,1. To find out in what ways maternal health communication occurred in radio,The general objective of this study is to explore the role of participatory communication in the promotion of maternal health care programmes,
 Uganda 2024-04-04 22:25:28 2027-04-04 Social Science and Humanities Non-Clinical Trial Degree Award
Simpson Nuwamanya
ID:
Feasibility of setting up solar powered oxygen supply in Rukungiri District, Uganda and in Butembo, DRC
REFNo: HS3587ES

Main Objective
This proposal seeks to demonstrate the feasibility of solar powered oxygen cylinder filling stations to supply medical oxygen to health facilities in Rukungiri District, Uganda and in Butembo, DRC.

Specific Aims
Describe the oxygen needs (survey of oxygen demand) and willingness-to-pay (market survey) at 14 medical facilities in Rukungiri District, Uganda, and 95 facilities in Butembo, DRC.
a. Specific: The aim is narrowly defined to include cylinder demand and price point.
b. Measurable: Survey data will measure cylinder need at each facility and price point (willingness to pay).
c. Achievable: The 14 sites in Uganda and 95 sites in DRC. We anticipate this survey will take approximately 30 minutes to complete, with on-site interview. Thus, the aim is achievable.
d. Relevant: These data are important for understanding the feasibility of supplying cylinders from a solar powered oxygen filling station.
e. Time-bound: Once approved, the study is anticipated to take 3 to 6 months to complete data collection. Data analysis and write-up of results is anticipated to take another 6 months.
2. Evaluate if solar powered cylinder filling is a feasible model to improve oxygen access.
a. Specific: The aim is narrowly defined to test the feasibility of the proposed cylinder filling stations.
b. Measurable: In order to be feasible, the costs and revenues need to be defined. These will be directly measured (recorded) based on the project activities (cylinder sales, equipment procurement).
c. Achievable: With partners (LeanMed), the cylinder filling stations can be implemented. Thereafter, the evaluation will be achievable.
d. Relevant: These data are important for understanding the real-world implementation of solar powered oxygen filling stations.
e. Time-bound: Once the study is approved and equipment is shipped and installed, we will evaluate project costs and revenues over a well-defined 12-month period.

Hypothesis
The working hypothesis is that solar powered oxygen filling stations are feasible and can generate revenue to maintain the ongoing provision of oxygen in areas where access is limited.

Uganda 2024-03-29 9:38:07 2027-03-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Richard Idro
ID: UNCST-2021-R013599
 Etiological role of parasitic exposure and familial susceptibility in nodding syndrome- related epilepsies
REFNo: HS3940ES

The central aim of this study is to investigate if families with nodding syndrome (NS) share common electrophysiological and clinical features forming a distinct familial epilepsy syndrome and if this phenotype is conferred by parasite, Onchocerca volvulus (OV)-associated hu-Leiomodin-1 antibodies in genetically susceptible individuals. This project provides a unique opportunity to mechanistically understand how the onchocerca parasite exposure modifies the risk for epilepsy among susceptible individuals.
Aim1: Characterize the epilepsy sub-phenotypes that aggregate within the NS-affected families. We hypothesize that a common electroclinical feature forms a distinct NS-associated familial syndrome.
Aim 2: Determine if distinct genetic polymorphism in the human host is associated with the pathogenesis of NS-and related epilepsies. Whole-exome/genome sequencing will be performed to test whether a genetic variant of major effect size co-segregates with NS and related epilepsies.
Aim 3: Evaluate the relationship between exposure to OV-associated Hu-leiomodin-1 antibody and host susceptibility that jointly confers risk for NS-and related epilepsies. We will test the hypothesis that OV -associated Hu-Leiomodin-1 antibodies in genetically susceptible individuals cause NS- related epilepsies.
 Uganda 2024-03-28 19:51:45 2027-03-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Felix Oyania
ID: UNCST-2021-R013492
 Understanding the Current Pediatric Radiology Imaging and Interpretation Capacity and Need In Mbarara, Uganda - A Survey
REFNo: HS3922ES

Objective 1: Needs assessment survey-To conduct a survey assessing the radiology imaging interpretation capacity and needs among medical providers involved with pediatric care in Mbarara Uganda.

Objective 2: Course Evaluation-To conduct a holistic evaluation of our future free remote pediatric surgical radiology course after at least 6 months of instruction.
Specific objectives:
 Uganda 2024-03-28 19:31:48 2027-03-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Namaganda Rehema Rehema
ID: UNCST-2024-R005390
 AGING WITH HIV IN UGANDA: Intersectional stigma, Ageism and adherence to ARVs among older persons in Uganda
REFNo: SS2484ES

The overall objective of this study is to investigate the experiences of living with HIV and accessing ART among older persons in Uganda. ,3. To examine experiences of intersectional stigma among older persons living with HIV ,2. To explore the intersection between Ageism and HIV stigma and how this might affect adherence and experiences of living with HIV among older persons ,1. To establish levels of adherence on ART among older persons living with HIV,
 Uganda 2024-03-28 19:29:32 2027-03-28 Social Science and Humanities Non-Clinical Trial Degree Award
Nishai Moodley
ID:
Global-to-local alignment mechanisms in governing large-scale irrigation schemes in Uganda: Trade-offs and synergies in the water-energy-food nexus
REFNo: SS2481ES

The main objective of this study analyses the alignment mechanisms between international and national development actors in large-scale irrigation schemes, and how this impacts WEF access of local households in Uganda. Put simply, this study aims to analyse the alignment between donors on the global level and departments on the national level, and the influence on households on the local level.
South Africa 2024-03-28 19:22:41 2027-03-28 Social Science and Humanities Non-Clinical Trial Degree Award
Veronica Nyakato
ID: UNCST-2022-R010786
 Improving the diagnosis and prognosis monitoring of children with leukemia at the Uganda Cancer Institute (UCI) by developing and implementing an algorithm for diagnosis and monitoring prognosis.
REFNo: HS3828ES

Aim 1: To understand the baseline practice of laboratory diagnosis and monitoring prognosis of patients with leukemia at the Peadiatric Oncology Unit of Uganda Cancer Institute (UCI), Kampala - Uganda. Objectives of Aim 1: 1) To describe the laboratory diagnostic pathway for children receiving care for leukemia at the Uganda Cancer Institute (UCI), Kampala, Uganda. 2) To explore the experiences of healthcare workers with the laboratory diagnosis and monitoring of prognosis of children receiving care for leukemia at the Uganda Cancer Institute (UCI), Kampala, Uganda. Aim 2: To develop an evidence-based algorithm for laboratory investigation, diagnosis, and monitoring treatment response for leukemia in children at the UCI. Objectives of aim 2: 1) To develop an evidence-based algorithm for laboratory investigation and diagnosis of children with suspected leukemia at the UCI. 2) To develop an evidence-based algorithm for laboratory monitoring of treatment response in children diagnosed with leukemia at the UCI. 3) To train healthcare workers at the UCI Peadiatric oncology Unit on the newly developed algorithms for laboratory diagnosis and treatment monitoring for children receiving care for leukemia at the UCI
 Uganda 2024-03-28 18:56:10 2027-03-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jack Willis
ID:
Health and Livelihood in Uganda: Health Insurance in Uganda
REFNo: SS2328ES

What is the most beneficial structure of a health insurance?,How does the copayment level affect health and financial outcomes? How do these affects compare to those of the premium?,How does the copayment level affect usage of healthcare overall? Indirectly, through its affect on insurance take-up, and directly, through its affect usage of healthcare conditional on purchasing insurance?,How does the copayment level affect insurance demand? Does it affect selection? How does the effect of changing the copay on demand compare to that of changing the premium?,investigate the role of the structure of the Streamline insurance product on household-level outcomes,
 UK 2024-03-28 18:51:16 2027-03-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
KANIKA  Jean-Claude MASSAMBA
ID:
effectiveness of vaginal misoprostol versus vaginal dinoprostone among pregnant women undergoing labor induction at Jinja regional Referral Hospital. (REC Approval: BSU-REC-2023-244)
REFNo: HS4007ES

To assess the Peripartum fetal complications as well as the maternal obstetrics outcomes in vaginal misoprostol group versus vaginal dinoprostone group at Jinja Referral Regional Teaching-Hospital maternity ward. ,The main goal of this study is to compare the effectiveness of vaginal misoprostol to vaginal dinoprostone and identify the feto-maternal complications in women undergoing labor induction at Jinja Referral Regional Teaching-maternity Hospital\'s unit.,
 Democratic Republic of Congo 2024-03-28 18:36:47 2027-03-28 Medical and Health Sciences Clinical Trial Degree Award
Patrick Kagurusi Tumusiime
ID: UNCST-2021-R012687
 END OF PROJECT EVALUATION FOR SOLAR FOR INCLUSIVE WASH SERVICE PROJECT IN PADER DISTRICT, UGANDA
REFNo: SS2408ES

Purpose of the evaluation The evaluation will assess project outcomes and impact of the project in six schools and 48 communities in Puranga and Tenam Sub-counties, Pader district, Uganda. The findings of the end of project evaluation will be compared with the baseline values on indicators collected at the beginning of the project. Specific objectives of the evaluation i. To assess the project performance against set indicator targets that were identified for outputs and outcomes. ii. To assess the viability, sustainability and cost-effectiveness of the Solar for Improved WASH services interventions in Pader district. iii. To identify learning from the solar for WASH services project and provide viable recommendations for implementation of similar projects in future.
Uganda 2024-03-28 18:23:45 2027-03-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
TIHARIHONDI HENRY
ID:
on Conflict Management Approaches and Strikes in Higher Educational Institutions in Uganda, a Comparative Study of Selected Private and Public Universities.
REFNo: SS2291ES

iv. To establish the relationship between conflict management approaches and strikes in private and public universities in Uganda.,iii. To determine the best conflict management approaches that can be applied to reduce strikes in private and public universities in Uganda.,ii. To explore the conflict management approaches used to reduce strikes in private and public universities in Uganda.,i. To examine the nature of strikes happening in private and public universities in Uganda. ,The Main objective of this study is to investigate the effectiveness of existing conflict management approaches on reducing strikes in selected private and public universities in Uganda,
 Uganda 2024-03-28 18:14:06 2027-03-28 Social Science and Humanities Non-Clinical Trial Degree Award
Jonathan Izudi
ID: UNCST-2019-R000469
 Effectiveness of Multi-Month Dispensing of Anti-Tuberculosis Drugs (MULTI-DAT) Versus Standard of Care on Treatment Success Rate Among People with Drug Susceptible Tuberculosis in Rural Eastern Uganda
REFNo: HS3953ES

To evaluate the effectiveness of MULTI-DAT on cure and treatment success rates at 6 months of treatment compared to the standard of care (SOC) using an open-label, individually randomized controlled trial or RCT (Aim 2). ,To explore stakeholder perceptions regarding the relevance and appropriateness of MULTI-DAT, including the delivery of MULTI-DAT among people with drug-susceptible PTB aged ≥15 years using a qualitative study (Aim 1).,Overall, the MORAD study will focus on the practicability and effectiveness of MULTI-DAT among people with drug-susceptible pulmonary TB (PTB) aged ≥15 years on the standard 6-month anti-TB treatment regimen in eastern Uganda,
 Uganda 2024-03-27 18:52:57 2027-03-27 Medical and Health Sciences Clinical Trial Non-degree Award
KABAGAMBE  DAVID JESSE
ID: UNCST-2023-R005585
 FINANCIAL INCLUSSION AND MICRO, SMALL AND MEDIUM ENTERPRISES (MSME’S) FINANCIAL PERFORMANCE IN UGANDA; A CASE OF AGRIBUSINESS ENTERPRISES IN SELECTED DISTRICTS IN KIGEZI SUB-REGION
REFNo: SS2409ES

1. To determine the effect of Access to finance services on the financial performance of micro, small and medium enterprises (MSME’s) in Uganda
2. To model the effect of Usage of Financial services on the financial performance of micro, small and medium enterprises (MSME’s) in Uganda
3. To assess the effect of Quality of Financial services on the financial performance of micro, small and medium enterprises (MSME’s) in Uganda
4. To identify the costs associated with financial inclusion on the financial performance of micro, small and medium enterprises (MSME’s) in Uganda
5. To draw conclusions and policy recommendations regarding financial inclusiveness financial performance of micro, small and medium enterprises (MSME’s) in Uganda


 Uganda 2024-03-27 18:41:45 2027-03-27 Social Science and Humanities Non-Clinical Trial Degree Award
Eva Smallegange Sophia
ID: UNCST-2023-R005788
 Feasibility trial for the PlayMatters program in refugee settlements in Uganda: a teacher professional development program aiming to improve teacher practices, child holistic outcomes and wellbeing by integrating Learning-through-Play as a pedagogical approach in schools
REFNo: SS2376ES

To assess the feasibility (from the perspective of the multi-language barrier ) of studying child-level outcomes as a primary question of the impact trial.,To assess the feasibility of cluster randomization trial procedures to limit biases and risk of contamination,To evaluate the fidelity of intervention delivery by PlayMatters trained implementers at each of the cascade levels of the intervention (master trainers, tutors and teachers),To evaluate the acceptability of the PlayMatters intervention in refugee settlements and host communities in Uganda ( Adjumani, Yumbe and Lamwo),
 Netherlands 2024-03-27 18:36:45 2027-03-27 Social Science and Humanities Non-Clinical Trial Non-degree Award
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