Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Naomi Nabami
ID: UNCST-2025-R018998
Women vendors: A history of female commercial activities across the Uganda-Congo border during the 20th century.
REFNo: SS4964ES

The first objective of this project is to contribute to women’s empowerment in the subregion by looking at their historical trajectory. It will also allow for historicizing ICBT between the DRC and Uganda, recentering female agency, and bringing in the Congolese perspective. The project fills in an important blank spot in our historical understanding of the Uganda-Congo border’s economic development by connecting the precolonial, colonial, and postcolonial contexts in which this trade took place. By recentering the overlooked role of women as commercial actors throughout the history of ICBT, the project investigates how trade connections evolved in times of war and forced displacement, but also in pre-conflict decades. This will result in a dissertation that focuses on the 20th century to the present.
Here are the specific objectives of the research:
RO1 – Historicizing ICBT between the DRC and Uganda: According to Titeca (2009), informal trade activities between DRC and Uganda must be understood through the lens of a complex history that includes ethnic interconnections and refugee fluxes. Yet they also build on historical relations and exchanges that predate the context of conflict or the Structural Adjustment Programs. The project fills in an important blank spot in our historical understanding of this border’s economic development by connecting the precolonial, colonial and postcolonial contexts in which this trade took place. By recentering the overlooked role of women as commercial actors throughout the history of ICBT, the project investigates how trade connections evolved in times of war and forced displacement, but also in pre-conflict decades. This will result in a dissertation that focuses on the period 1850 to present.
RO2 – Recentering female agency: Public discourse about the border area under study, particularly the Congolese side, often portrays women as mere victims of a conflict-prone context. While sexual violence is indeed used as a weapon of war in this region, with cases dating back to colonial abuses (see Mertens 2023), it is crucial to also pay attention to the ways in which these women have shaped their livelihoods, generated forms of economic autonomy, and evaded male control (see for example Obbo 1980, MacGaffey 1988). Because of its informal character, ICBT generates specific regulatory dynamics, which not only require negotiation with state officials, but also with the broader population (see Titeca 2012). However, we know very little about the ways in which women have navigated this commercial ecosystem. Therefore, their agency is the starting point of this research project (see Thomas 2016). By applying an interdisciplinary approach and using a variety of sources, the project tackles the methodological challenges that have hitherto played a role in the overlooking of Central African female histories.
RO3 – Bringing in the Congolese perspective :Informal export from Uganda to the DRC continues to grow rapidly, with the DRC making up 49,4% of Uganda’s total informal exports in 2018, in comparison to 27,1% in 2010 (Titeca 2020: 3). While this project does not have the ambition to add quantitative data from the Congolese side to the debate, it is innovative in its historical attention to the activities, experiences and livelihoods of Congolese female experiences in this border area. The informality of their activities and the lack of control over mobility was a general source of distress for the colonial government, especially in border areas (see for example Mathys forthcoming). Recent doctoral research by Aurélie Bouvart (2024) even suggests that Congolese women who were brought to court in the Belgian Congo were mostly convicted for “crimes” related to unauthorized mobility. This project, therefore, contributes a critical new perspective by foregrounding the agency of Congolese women and by highlighting the historical continuities in their strategies for navigating both economic and social landscapes across the Congolese-Ugandan border.
Democratic Republic of Congo 2026-04-02 17:52:15 2029-04-02 Social Science and Humanities Non-Clinical Trial Degree Award
Mohamed Sesay
ID:
Traditional authorities in contemporary governance systems in Africa: Uganda, Ghana, and Sierra Leone in comparative perspectives
REFNo: SS5086ES

The main purpose of this comparative study of Uganda, Sierra Leone, and Ghana is to compare and contrast how traditional rulers relate with the state in contemporary governance systems.
The specific objectives of this study include the following:
• Compare the nature and strength of traditional authority in Uganda, Sierra Leone, and Ghana so as to understand how they have evolved and adapted to changes in contemporary governance
• Examine how chiefs exercise their authority in relations to other powerholders in specific contexts taking into account changing political, socioeconomic, and cultural
circumstances
• Trace the evolution of chiefs' relations with other authorities in contemporary times both at the national and subnational levels of governance.
• Analyze the comparative effect of reform policies on chiefs, including initiatives intended to liberal-democratic standards of governance


Sierra Leone 2026-04-02 17:45:23 2029-04-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
CHRISTINE JOYCE ANGIMA
ID: UNCST-2025-R022785
EFFICACY AND ACCEPTABILITY OF PSYCHOTHERAPY INTERVENTION AND SELF-ESTEEM AMONG PREGNANT ADOLESCENTS: A CASE OF KATAKWI DISTRICT GENERAL HOSPITAL
REFNo: SS5028ES

General Objective: To assess the efficacy and acceptability of psychotherapy interventions in improving self-esteem among pregnant adolescents attending Katakwi District General Hospital in Uganda. Specific Objectives: 1. To determine the level of self-esteem among pregnant adolescents attending Katakwi District General Hospital. 2. To assess the effectiveness of psychotherapy interventions in improving self-esteem among pregnant adolescents. 3. To examine the acceptability of psychotherapy interventions among pregnant adolescents receiving care at Katakwi District General Hospital.
Uganda 2026-04-02 17:43:08 2029-04-02 Social Science and Humanities Non-Clinical Trial Degree Award
Matthias Miti
ID: UNCST-2025-R021994
Gendered Effects of Land Documentation on Agricultural Livelihoods in Busoga Sub-Region
REFNo: SS4812ES

i. To establish the nature of gender disparities in the ownership of documented land in Busoga sub-region ii. To investigate the socio-cultural barriers that limit women’s ownership of documented land for agricultural livelihoods in Busoga sub-region iii. To assess how land documentation influences agricultural livelihoods differently for women and men in Busoga sub-region.
Uganda 2026-04-02 17:41:54 2029-04-02 Social Science and Humanities Non-Clinical Trial Degree Award
Nixon Niyonzima
ID: UNCST-2020-R014577
Modeling the Economic Benefit of Low-Cost Laparoscopic vs. Open Surgery for Chest and Abdominal Cancers in Uganda
REFNo: HS6245ES

Aim 2: Measure the economic outcomes of laparoscopic surgery using KeyScope versus the standard of care (open surgery or open biopsy), including pre- and post-operative costs, among a simulated cohort of patients with cancer needing biopsy or resection.,Aim 1: Measure the risk of CHE and impoverishment due to medical and non-medical costs among individuals seeking surgical care for cancers in the chest and abdomen at the Uganda Cancer Institute.,
Uganda 2026-04-02 17:39:02 2029-04-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Thomas Buyinza
ID: UNCST-2025-R016827
MINIMIZING AFLATOXIN CONTAMINATION IN MAIZE ACROSS THE SUPPLY CHAIN THROUGH FARMER–LED PARTICIPATORY TRAINING IN KAMULI, EASTERN UGANDA: A PILOT RANDOMIZED CONTROLLED TRIAL
REFNo: A743ES

General Objective: To evaluate the effectiveness of farmer-led participatory training in improving farmers’ knowledge, attitudes, and practices and reducing aflatoxin contamination in maize across the supply chain in Kamuli District, Eastern Uganda.

Specific Objectives
i. To enhance farmers’ knowledge, attitudes, and practices on Aflatoxin contamination and its health risks in Kamuli District, Uganda.
ii. To minimize Aflatoxin levels in maize to within acceptable limits set by the Uganda National Bureau of Standards in Kamuli District, Uganda.

Uganda 2026-04-02 17:36:12 2029-04-02 Agricultural Sciences Non-Clinical Trial Non-degree Award
Doreen Nakagaayi
ID: UNCST-2023-R006587
Assessment of a Novel Dual-Screen Model for Rheumatic Heart Disease Diagnosis: A Diagnostic Accuracy Study
REFNo: HS7123ES

To assess the inter-rater reliability between the two ADUNU-trained non-expert providers within the dual-provider diagnostic model, and to evaluate factors associated with discordant interpretations. ,To optimize the diagnostic performance of the dual-provider diagnostic model by using a receiver operating curve to identify optimal cutoff values for mitral and aortic regurgitation jet lengths that maximize its sensitivity and specificity for RHD diagnosis.,Secondary Aims To compare the diagnostic performance (sensitivity, specificity, and overall accuracy) among three distinct echo models and the current diagnostic gold standard. ,Primary Aim To determine the diagnostic performance (sensitivity, specificity, and overall accuracy) of the dual-provider diagnostic model compared to the current diagnostic gold standard of expert clinician interpretation using a fully functional echocardiography machine and comprehensive diagnostic protocol.,
Uganda 2026-04-02 17:34:59 2029-04-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Victor Musiime
ID: UNCST-2021-R013794
Experiences of caregivers and healthcare providers regarding post-discharge mortality and health-seeking behavior in life-threatening scenarios for children living with HIV in Uganda, Africa: a qualitative study
REFNo: HS7286ES

1. To explore experiences of caregivers and healthcare providers regarding PDM among children living with HIV after discharge from hospital. 2. To describe the role of social, cultural, economic and environmental context in health-seeking behavior after discharge for children living with HIV. 3. To explore perceived risk factors for post-discharge mortality among children living with HIV from the perspective of caregivers and health workers. 4. To describe strategies to prevent PDM among children living with HIV from the perspective of caregivers and health workers.
Uganda 2026-04-02 12:46:45 2029-04-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Waiswa Peter
ID: UNCST-2020-R014921
An effectiveness-implementation trial of a peer mentorship intervention to help women navigate barriers to contraceptive use in rural Uganda
REFNo: HS7355ES

Main objective
: Our main aim is to increase women’s ability to overcome barriers to contraceptive use and to support adoption of self-injectable contraception. After promising findings in our pilot study, we propose to build on our strong, ongoing partnership between Makerere University in Uganda and the University of California, San Francisco to test “I-CAN” intervention on a larger scale.
Objectives
1. To test the effectiveness of a peer mentorship intervention on contraceptive use and contraceptive self-injection (Aim 1).
2. To examine the process of implementing I-CAN intervention; the ICAN’s reach to mentees, differential effectiveness, adoption and maintenance by mentors, implementation fidelity and innovations, and contextual factors (Aim 2)
3. To examine the cost-effectiveness of the peer mentorship intervention versus standard of care (counselling by health facility or community health workers) in supporting contraceptive use and contraceptive self-injection (Aim 3).

Uganda 2026-04-02 12:45:33 2029-04-02 Medical and Health Sciences Clinical Trial Non-degree Award
Godwin Godwin Tumuhairwe
ID: UNCST-2025-R021782
PRIVATE FINANCING, FINANCIAL MANAGEMENT SKILLS AND PERFORMANCE OF VOCATIONAL INSTITUTIONS IN BUSHENYI DISTRICT IN WESTERN UGANDA
REFNo: SS4955ES

i. To assess how source of financing affects the enrollment and performance of vocational institutions in Bushenyi District, Uganda
ii. To examine the relationship between private financing and resource utilization to vocational institutions training in Bushenyi District
iii. To examine the relationship between financial management skills and the performance of vocational institutions in Bushenyi District

Uganda 2026-04-02 12:35:27 2029-04-02 Social Science and Humanities Non-Clinical Trial Degree Award
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