Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Isaac Ssewanyana
ID: UNCST-2020-R014336
Performance evaluation of an improved point-of-care test (dual target) SAMBA HIV-1 qualitative test for early infant diagnosis of HIV-1 infection in resource-poor healthcare settings
REFNo: HS2219ES

To verify the field performance (sensitivity and specificity) of the improved, dual-target SAMBA II HIV-1 Qual Test against routine Cobas Ampliprep/Taqman HIV-1 Qualitative Test Version 2.0 (DBS)- for early diagnosis of HIV-1 in exposed infants and adults. In addition, discrepant results will be analysed using Cepheid Xpert HIV-1 Qual ,
Uganda 2022-05-04 11:32:24 2025-05-04 Medical and Health Sciences Clinical Trial Non-degree Award
Peter Jackson Durham
ID: UNCST-2022-R010933
Investigation of Serologic and Pulmonary Mediators of post-Tuberculosis Lung Fibrosis in a Ugandan cohort
REFNo: HS2172ES

Primary objective:
-To analyze the levels of cytokines and SPM’s in the blood and exhaled breath of patients with pulmonary TB at diagnosis, 6 months and one year to determine if there are differences in cytokine and SPM expression among patients who develop PTLI and those who do not.
Secondary objectives
-To identify socio-demographic and clinical risk factors associated with PTLI development and investigate associations of these characteristics with specific PTLI phenotypes.
-To document the quality of life among patients who develop PTLI. ? To develop a biobank of EBC and serum samples from subjects with PTLI and those with resolution of their lung impairment at diagnosis, conclusion of treatment and at one year from diagnosis.
USA 2022-05-04 11:28:09 2025-05-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JOYCE SHOMI ANDREW
ID:
FACTORS AFFECTING ADHERENCE TO ANTIHYPERTENSIVE MEDICATION AMONG HYPERTENSIVE PATIENTS IN WAKISO PUBLIC HOSPITALS.
REFNo: HS2163ES

I. To determine the level of adherence to antihypertensive medication among hypertensive patient in Wakiso and Kasangati public health facilities.
II. To determine patient related factors affecting adherence to antihypertensive medication in Wakiso and Kasangati public health facilities.
III. To determine clinical related factors affecting adherence to antihypertensive medication in Wakiso and Kasangati public health facilities.
IV. To determine medication related factors affecting adherence to antihypertensive medication in Wakiso and Kasangati public health facilities.

Tanzania 2022-05-03 14:26:47 2025-05-03 Medical and Health Sciences Non-Clinical Trial Degree Award
Hedwig Acham
ID: UNCST-2022-R011459
Developing a photographic Figure-Rating Scale to reduce malnutrition among infants and young children of mothers with a low level of literacy in Buyende district
REFNo: HS2137ES

1) To develop an innovative photographic figure-rating rating scale, for use at local level to assess nutritional status of children at 9 months
2) To determine accuracy, perception and satisfaction of mothers with use of the tool for predicting the nutritional status of their children.

Uganda 2022-05-03 13:39:52 2025-05-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
MILTON NUWABIMPA RWIITA
ID:
THE QUALITY OF HIGHER EDUCATION AND EMPLOYABILITY OF GRADUATES FROM SELECTED UNIVERSITIES IN SOUTH WESTERN UGANDA
REFNo: SS1275ES

1. To determine the relationship between the quality of curriculum and the employability of graduates from selected Universities in South Western Uganda.
2. To establish the relationship between the quality of students enrolled in the University and the employability of graduates from selected Universities in South Western Uganda.
3. To establish the relationship between the quality of teaching and the employability of graduates from selected Universities in South Western Uganda.

Uganda 2022-05-03 13:06:09 2025-05-03 Social Science and Humanities Non-Clinical Trial Degree Award
Emmanuel Sendaula
ID: UNCST-2020-R014767
Utility of the interRAI Check-Up Comprehensive Geriatric Assessment (CGA) Tool: Evaluating Check-Up Acceptability in Assessing Frailty and Care Needs of Older Adults with Human Immunodeficiency Virus (HIV) in Kampala District of Uganda
REFNo: HS2229ES

- determine the acceptability and perceptions of using a standardized instrument for assessment and care planning for older persons living with HIV,- identify specific care needs of older adults living with HIV,- estimate the association between HIV status and (i) one primary outcome; activities of daily living, and (ii) two secondary outcomes; health stability and cognitive function in older persons,- characterize the sociodemographic, clinical, neuropsychiatric, and functional characteristics of older persons living with and without HIV,
Uganda 2022-05-03 13:04:16 2025-05-03 Medical and Health Sciences Non-Clinical Trial Degree Award
Moses Mukuru
ID:
A LANDSCAPE ANALYSIS OF THE LOCAL CONTEXT, CHALLENGES, AND OPPORTUNITIES FOR DIGITIZED HEALTH WORKER PAYMENTS IN AFRICA
REFNo: HS2216ES

7. To develop a research and policy reform agenda for digital Payment for health workers during implementation of ng health programs Africa.,6. To explore the influence of gender on digital payment for health workers in Uganda,5. To describe successes and challenges encountered in using health worker digital payments in Africa,4. To describe contextual factors influencing e-payment uptake and use in Africa. ,3. To determine the availability of the technical tools needed to implement digital payments in Africa,2. To describe access to existing digital payment systems and modalities for health workers (formal/informal workers) in Africa. ,1. To map the key stakeholders and programs, their influence, and their role in digital payment for health workers in Africa,The overall objective of this landscape analysis is to synthesize evidence on existing digital payment systems in Africa with a focus on policies/laws, technology, actors/stakeholders, programs, challenges/barriers, enablers, and benefits/impact of digital payment for health workers. ,
Uganda 2022-05-03 12:57:24 2025-05-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joshua Parker Allen David Franz
ID:
HIV in Epidemiologyland: the politics of transnational research in the age of global health
REFNo: SS1262ES

(1) understand the perspectives of those working in public health research partnerships on research design, implementation, analysis, and findings-dissemination in the context of transnational collaborations; (2) to generate ideas of how research collaborations can be made more equitable; (3) to understand how the social sciences feature in scientific public health research.
UK 2022-05-03 12:54:51 2025-05-03 Social Science and Humanities Non-Clinical Trial Degree Award
IBRAHIM KASIRYE
ID:
Evaluating the Refugees in East Africa: Boosting Urban Innovations for Livelihoods Development (Re:Build) Program, Uganda
REFNo: SS1243ES

The overall goals of the RCT will be to test the effectiveness of a mentorship program for microentrepreneurs. The RCT will be informed by previous and ongoing activities undertaken by IRC as part of their regular programming. We will (i) measure the economic and psychological impacts of this intervention; (ii) measure whether a “shared fate” structure encourages mentors to invest additional effort in the mentees’ business and/or disclose valuable information or techniques, by giving mentors a stake in the mentees’ business; and (iii) evaluate whether matching between mentors and microenterprise participants across different demographics (Ugandans, refugees, men, women, etc.) confers greater benefits to participants than matching within demographics.
Uganda 2022-05-03 12:52:39 2025-05-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
Freda Wolfenden Janet
ID:
Strengthening School Leadership Towards Improving School Resiliency: An Improvement Science Approach
REFNo: SS893ES

General Objective: Contribute to improved quality and equity of the continued learning and well-being of girls and boys in the Global South during the prolonged school closures of the COVID-19 crisis, and future emergencies

Specific Objectives1.Knowledge Generation. Deepen understanding of how an improvement science approach can strengthen instructional school leadership towards school resiliency in a range of Global South contexts.

2.Capacity Building. Build the capacity of school leaders for data-driven decision-making and problem-solving leading to improvement.

3.Policy and Practice Influence. To inform education policy and practice on strengthening instructional school leadership and building school resiliency using the improvement science approach.
UK 2022-04-29 2025-04-29 Social Science and Humanities Non-Clinical Trial Non-degree Award
Irene Mbatidde
ID:
ANTIMICROBIAL USE AND RESISTANCE IN POULTRY PRODUCTION CHAINS IN SOROTI AND WAKISO DISTRICT, AND THE ASSOCIATED OCCUPATIONAL HEALTH RISKS
REFNo: A166ES

General Objective Understanding antimicrobial use patterns, their influence on the development of AMR along the poultry value chains and associated health risk factors among value chain workers in Wakiso and Soroti districts Specific Objectives Describe antimicrobial use patterns under intensive and free-range poultry production systems in Wakiso and Soroti respectively • Explain AMR for selected antibiotics at various points along the poultry production chain in Wakiso and Soroti districts • Develop a risk pathway for poultry associated AMR in Wakiso and Soroti • Quantify residues of (sulphurdiazine, tetracycline, neomycin) in poultry meat
Uganda 2022-04-28 2025-04-28 Agricultural Sciences Non-Clinical Trial Degree Award
Simon Peter Kibira Peter Sebina
ID: UNCST-2019-R000492
Covid-19 vaccine hesitancy among school teachers: a qualitative exploration of the driving factors
REFNo: SS1242ES

1.To explore the contextual, vaccine-specific, individual and group-specific drivers of Covid-19 vaccine hesitancy among school teachers in Uganda.
2.To explore facilitators of vaccine uptake for Covid-19 among school teachers in Uganda.
3.To describe the product attributes of the ideal Covid-19 vaccine from the perspective of school teachers.
Uganda 2022-04-27 2025-04-27 Social Science and Humanities Non-Clinical Trial Non-degree Award
Dennis Muhanguzi
ID: UNCST-2019-R001101
Evaluation of the Safety , Efficacy and Stability of Sangatraz®-125 & Sangatraz®-250: A Randomised Single-Blinded Positive Controlled Multi-Site Acaricides Field Trial
REFNo: A186ES

General objectives To determine the efficacy, safety and stability of Sangatraz®-125 & Sangatraz®-250(Sanga Vet. Chem. Ltd, Kampala Industrial Park, Namanve ) when applied onto cattle by hand spraying and plunge dipping for tick control. Specific objectives The specific objectives of this acaricide field trial will to to determine; i.efficacy of Sangatraz®-125 & Sangatraz®-250 when applied onto cattle by hand spraying and plunge dipping for tick control. ii.safety of Sangatraz®-125 & Sangatraz®-250 when applied onto cattle by hand spraying and plunge dipping for tick control. iii.Stability of Sangatraz®-125 & Sangatraz®-250 when applied onto cattle by plunge dipping for tick control.
Uganda 2022-04-25 2025-04-25 Agricultural Sciences Clinical Trial Non-degree Award
Marie Sabacka
ID:
Microbial diversity of disappearing tropical glaciers in Uganda
REFNo: NS348ES

Study microbial diversity of disappearing glaciers in Uganda
Czech Republic 2022-04-25 2025-04-25 Natural Sciences Non-Clinical Trial Non-degree Award
Gladys Ayot Florence
ID:
Exploring Experiences of Domestic Violence for Female Teachers in Secondary Schools in Uganda
REFNo: SS1273ES

4. Explore the support mechanism available to female teachers affected by domestic violence.,3. Provide a description of female teachers’ reports on how staff affected by domestic violence negotiates through the challenges of domestic violence in performing their duties.,2. Assess the female teachers’ perspectives about the impact of domestic violence on the administrative roles of teachers.,1. Assess from the female teachers’ perspective how domestic violence affects teachers’ teaching function/roles.,The purpose of this study is to explore the experiences of female teachers affected by domestic violence, describe how domestic violence affects the professional roles of a teacher of secondary schools and to establish how administrators manage the situation for affected staff in schools in northern Uganda.,
Uganda 2022-04-22 2025-04-22 Social Science and Humanities Non-Clinical Trial Degree Award
Rhoda Wanyenze
ID: UNCST-2021-R013352
LINKAGES BETWEEN SUSTAINABLE DEVELOPMENT GOALS IN UGANDA - A FOCUS ON HEALTH
REFNo: HS2015ES

To understand how stakeholders in Uganda perceive and assess linkages between health and non-health determinants and their impact.,To determine the strength, position, and nature of linkages between health and other SDGs in Uganda using the SDG synergies approach. ,The overall aim of this project is to identify, describe, and classify linkages between SDGs focusing on health at the country level in Uganda.,
Uganda 2022-04-22 2025-04-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Stavia Turyahabwe Stavia
ID: UNCST-2022-R011373
EXPLORING THE PATHWAYS OF LEPROSY FROM COMMUNITIES TO DIAGNOSIS TO FINE-TUNE INTERVENTIONS IN THE DISTRICTS OF MAYUGE, YUMBE AND KASESE, UGANDA
REFNo: SS1182ES

1. To describe the reasons for delay in seeking health care for leprosy patients diagnosed in three districts of Mayuge, Yumbe and Kasese
2. To describe the knowledge, attitude and practice among members of communities and health care providers in reference to leprosy

Uganda 2022-04-22 2025-04-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Francis Kakooza
ID:
Molecular Epidemiology and Antimicrobial Resistance Determinants of Neisseria gonorrhoeae among males with urethritis in Kampala, Uganda
REFNo: HS2191ES

Main Objective
To elucidate the genomic epidemiology and AMR determinants associated with NG strains circulating in Kampala Uganda
Specific Objectives
• To describe the NG AMR Surveillance Programme in Kampala, Uganda and the emerging phenotypic antimicrobial susceptibility data generated using E-test method
• To determine the genomic epidemiology of NG strains circulating in Kampala, Uganda using WGS and compare findings with behavioural, demographic and clinical metadata
• To identify the molecular AMR determinants associated with decreased susceptibility and/or resistance to NG using WGS and correlate with phenotypic AMR data

Uganda 2022-04-22 2025-04-22 Medical and Health Sciences Non-Clinical Trial Degree Award
Shana Warren
ID:
Vitamin A Supplementation (VAS) Post Event Coverage Survey (PECS) in Uganda
REFNo: SS1261ES

To conduct a PEC survey for the October-November 2021 round of the ICHD in Uganda,
USA 2022-04-21 2025-04-21 Social Science and Humanities Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
Routine SARS CoV-2 screening using Antigen Rapid diagnostic test to detect and control transmission of infections in markets and trade hubs in Kampala City – A pilot study.
REFNo: HS2197ES

4. To estimate the cost of implementing routine use of SARS CoV-2 Ag RDTs in markets and trade hubs,3. To assess the feasibility of use of Ag-RDTs in contact tracing for early identification of SARS-CoV-2 infections,2. To identify high risk groups that drive SARS-CoV-2 transmission in markets and trade hubs ,1. To pilot the use of routine SARS-CoV-2 Ag-RDT for the early detection of SARS-CoV-2 infections in markets and trading hubs within Kampala to control transmission ,
Uganda 2022-04-21 2025-04-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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