Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
SAMANYA  BULHAN
ID:
Decentralization and Service Quality in Healthcare sector of Uganda : A Case of Busoga Sub-Region
REFNo: SS2490ES

5.To validate the inter-district healthcare model of Busoga sub-region. ,3.To design an inter-district healthcare model to improve on service quality in Busoga Sub-region . ,2.To examine the differences in service quality provision among the district hospitals in Busoga Sub-region .,1.To investigate the theoretical implication on decentralization and service quality in healthcare sector of Busoga Sub-region. ,The purpose of the study is to evaluate Decentralization and Service Quality in health care sector of Uganda a case of Busoga Sub-Region. ,
United Kingdom 2024-04-09 18:33:53 2027-04-09 Social Science and Humanities Non-Clinical Trial Degree Award
Eve  Namisango
ID: UNCST-2021-R014038
Integration of child- and family-centred outcome measurement into routine palliative care to drive person-centredness and quality in Uganda.
REFNo: HS3578ES

1) To develop a child expert group to advise and act as peer promoters.
2) To refine C-POS for implementation across age groups and diagnoses.
3) To develop a quality improvement team within each of our three demonstration sites and
identify site-specific integration plans.
4) To develop a Decision Support Tool (DST) specifying appropriate and feasible clinical
responses to real-time data that are feasible and effective within local resources.
5) To implement C-POS for quality improvement cycles within routine practice in three
demonstration sites.
6) To determine stakeholder views on quality improvement mechanisms and impact.
7) To develop an implementation manual with consortium partners for the region.
Uganda 2024-04-09 18:21:39 2027-04-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Christine Ampumuza
ID: UNCST-2023-R007425
Modelling Domestic Tourism on Demand and Supply Factors in Uganda RefNo:
REFNo: SS2489ES

iv. To examine the impact of demand and supply factors on domestic tourism consumption in Uganda using econometrics models.,iii. To determine the demand factors influencing domestic tourism consumption in Uganda.,ii. To identify the supply factors influencing domestic tourism consumption in Uganda.,i. To assess the current status of domestic tourism in Uganda.,To identify the supply and demand factors that influence domestic tourism and to develop a model for its promotion in Uganda. ,
Uganda 2024-04-09 18:13:48 2027-04-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ismael Ddumba-Nyanzi Elisha
ID: UNCST-2024-R005106
Evaluation of the Kulea Watoto Project
REFNo: SS2474ES

1. Evaluate the effect of the Kulea Watoto (KW) Project on the following outcomes:
a) Early learning
b) Responsive caregiving knowledge and practices of parents and caregivers.
c) Household economic well-being
d) Child health and development
e) Psychosocial health and well-being of the child and primary caregiver
2. Qualitatively assess the pathways/mechanisms for impact, satisfaction, and the perceived usefulness of the individual components on well-being of children and caregivers. Further, it seeks to understand continuously the implementation feasibility of the intervention components.

Uganda 2024-04-04 8:29:45 2027-04-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
Patricia NAHIRYA Ntege Nahirya
ID: UNCST-2019-R001117
Long-Term Follow-Up of CAB LA for Participants in HPTN 083 and HPTN 084 CAB PrEP Studies at Risk of HIV Acquisition.
REFNo: HS3876ES

Primary Objective
• To describe new HIV infections in adult and adolescent participants at risk of HIV acquisition included in the HPTN 084 studies and their associated sub-studies.

Secondary Objective
• To describe any serious adverse events (SAEs), Grade 3 and Grade 4 ISRs, and AEs leading to withdrawal in adult and adolescent participants included in the HPTN 084 studies and their associated sub-studies.


Uganda 2024-04-04 8:20:33 2027-04-04 Medical and Health Sciences Clinical Trial Non-degree Award
Firminus  Mugumya
ID:
FORMATIVE RESEARCH ON EARLY CHILDHOOD DEVELOPMENT IN NAKIVAALE REFUGEE SETTLEMENT
REFNo: SS2041ES

The overall aim of the implementation research study is to co-design, implement and evaluate an innovative integrated ECD intervention that promotes positive outcomes for refugee children in Nakivaale refugee settlement. This study protocol outlines the formative research to support the development of the intervention, The specific objectives of the formative research are as follows:

1. To describe the current developmental status of children (0-5) in Nakivaale refugee settlement
2. To map formal and informal ECD services in the Nakivaale refugee settlement
3. To understand the current caregiving knowledge, attitudes and practices, in the five domains of the nurturing care framework in the refugee and host setting of Nakivaale refugee settlement;
4. The understand the enabling and influencing factors and barriers to ECD service provision and caregiving among service providers and caregivers

Uganda 2024-04-04 8:07:24 2027-04-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
Joseph Kiva S.
ID:
Exploring the role of participatory communication in the promotion of maternal health care programmes: A case study of 89.2 Central Broadcasting Services FM in Uganda.
REFNo: SS2231ES

4. To find out in what ways has the programme facilitated community dialogue in the promotion of maternal health among pregnant women and mothers.,3. To explore the pregnant women/mothers’ perceptions of the participatorycommunication channels used during the health programme,2. To explore the participatory communication approaches used in the health programme,1. To find out in what ways maternal health communication occurred in radio,The general objective of this study is to explore the role of participatory communication in the promotion of maternal health care programmes,
Uganda 2024-04-04 22:25:28 2027-04-04 Social Science and Humanities Non-Clinical Trial Degree Award
Simpson Nuwamanya
ID:
Feasibility of setting up solar powered oxygen supply in Rukungiri District, Uganda and in Butembo, DRC
REFNo: HS3587ES

Main Objective
This proposal seeks to demonstrate the feasibility of solar powered oxygen cylinder filling stations to supply medical oxygen to health facilities in Rukungiri District, Uganda and in Butembo, DRC.

Specific Aims
Describe the oxygen needs (survey of oxygen demand) and willingness-to-pay (market survey) at 14 medical facilities in Rukungiri District, Uganda, and 95 facilities in Butembo, DRC.
a. Specific: The aim is narrowly defined to include cylinder demand and price point.
b. Measurable: Survey data will measure cylinder need at each facility and price point (willingness to pay).
c. Achievable: The 14 sites in Uganda and 95 sites in DRC. We anticipate this survey will take approximately 30 minutes to complete, with on-site interview. Thus, the aim is achievable.
d. Relevant: These data are important for understanding the feasibility of supplying cylinders from a solar powered oxygen filling station.
e. Time-bound: Once approved, the study is anticipated to take 3 to 6 months to complete data collection. Data analysis and write-up of results is anticipated to take another 6 months.
2. Evaluate if solar powered cylinder filling is a feasible model to improve oxygen access.
a. Specific: The aim is narrowly defined to test the feasibility of the proposed cylinder filling stations.
b. Measurable: In order to be feasible, the costs and revenues need to be defined. These will be directly measured (recorded) based on the project activities (cylinder sales, equipment procurement).
c. Achievable: With partners (LeanMed), the cylinder filling stations can be implemented. Thereafter, the evaluation will be achievable.
d. Relevant: These data are important for understanding the real-world implementation of solar powered oxygen filling stations.
e. Time-bound: Once the study is approved and equipment is shipped and installed, we will evaluate project costs and revenues over a well-defined 12-month period.

Hypothesis
The working hypothesis is that solar powered oxygen filling stations are feasible and can generate revenue to maintain the ongoing provision of oxygen in areas where access is limited.

Uganda 2024-03-29 9:38:07 2027-03-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Richard Idro
ID: UNCST-2021-R013599
Etiological role of parasitic exposure and familial susceptibility in nodding syndrome- related epilepsies
REFNo: HS3940ES

The central aim of this study is to investigate if families with nodding syndrome (NS) share common electrophysiological and clinical features forming a distinct familial epilepsy syndrome and if this phenotype is conferred by parasite, Onchocerca volvulus (OV)-associated hu-Leiomodin-1 antibodies in genetically susceptible individuals. This project provides a unique opportunity to mechanistically understand how the onchocerca parasite exposure modifies the risk for epilepsy among susceptible individuals.
Aim1: Characterize the epilepsy sub-phenotypes that aggregate within the NS-affected families. We hypothesize that a common electroclinical feature forms a distinct NS-associated familial syndrome.
Aim 2: Determine if distinct genetic polymorphism in the human host is associated with the pathogenesis of NS-and related epilepsies. Whole-exome/genome sequencing will be performed to test whether a genetic variant of major effect size co-segregates with NS and related epilepsies.
Aim 3: Evaluate the relationship between exposure to OV-associated Hu-leiomodin-1 antibody and host susceptibility that jointly confers risk for NS-and related epilepsies. We will test the hypothesis that OV -associated Hu-Leiomodin-1 antibodies in genetically susceptible individuals cause NS- related epilepsies.
Uganda 2024-03-28 19:51:45 2027-03-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Felix Oyania
ID: UNCST-2021-R013492
Understanding the Current Pediatric Radiology Imaging and Interpretation Capacity and Need In Mbarara, Uganda - A Survey
REFNo: HS3922ES

Objective 1: Needs assessment survey-To conduct a survey assessing the radiology imaging interpretation capacity and needs among medical providers involved with pediatric care in Mbarara Uganda.

Objective 2: Course Evaluation-To conduct a holistic evaluation of our future free remote pediatric surgical radiology course after at least 6 months of instruction.
Specific objectives:
Uganda 2024-03-28 19:31:48 2027-03-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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