Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Eugene Ruzagira
ID: UNCST-2023-R008282
 A Phase 3, Randomized, Active-Controlled, Double-Blind Clinical Study to Evaluate the Efficacy and Safety of MK-8527 Oral Once-Monthly as HIV-1 Preexposure Prophylaxis in Women
REFNo: HS6565ES

To evaluate the efficacy of MK-8527 qm compared to FTC/TDF qd for the prevention of HIV-1 infection as assessed by the incidence rate per year of adjudicated HIV-1 infections To evaluate the safety and tolerability of MK-8527 qm compared to FTC/TDF qd.
 Uganda 2025-11-21 11:18:30 2028-11-21 Medical and Health Sciences Clinical Trial Non-degree Award
Francis Ssebiryo
ID: UNCST-2019-R001250
 Mid-Term Evaluation for the Stand Up for Sexual and Reproductive Health Rights Project
REFNo: SS4574ES

To establish a midline value for key performance indicators outlined in the project’s Performance Measurement Framework(PMF), allowing for a direct comparison with the baseline data. To assess progress toward the Outcome Indicators. To establish a midline value for tracking progress against these outcome indicators, as detailed in the project’s Performance Measurement Framework (PMF). To provide recommendations for strategic project improvements
 Uganda 2025-11-19 8:42:04 2028-11-19 Social Science and Humanities Non-Clinical Trial Non-degree Award
Eddy Walakira Joshua
ID: UNCST-2022-R009077
 MULTI-COUNTRY OPERATIONAL RESEARCH ON NEW AND EVOLVING FORMS OF VIOLENCE AGAINST WOMEN AND GIRLS LIVING WITH HIV IN UGANDA, KENYA AND TANZANIA
REFNo: SS4545ES

Aim
To conduct a multi-country operational research that examines how new and evolving forms of violence against WLHIV affect their participation in leadership and collective organising within feminist movements in Uganda, Kenya, and Tanzania.

Specific objectives
1.To assess the lived experiences of WLHIV regarding new and evolving forms of violence, and their impact on participation, leadership, and collective organising within feminist movements in Uganda, Kenya, and Tanzania.
2.To examine the experiences of WLHIV who seek or do not seek assistance after experiencing violence, including their access to shelters and support services, and how these factors influence movement-building participation and their advocacy.
3.To analyse, by root cause, how existing barriers hinder WLHIV from receiving assistance and participating meaningfully in coalition-building, advocacy spaces, and feminist leadership.
4.To generate feminist, practice-based evidence and approaches to strengthen inclusive coalitions, leadership pathways, and evidence-informed advocacy under the THRIVE Project at regional levels.
 Uganda 2025-11-19 16:37:11 2028-11-19 Social Science and Humanities Non-Clinical Trial Non-degree Award
Mary Kaakyo
ID: UNCST-2025-R019146
 Impact of Differentiated Service Delivery (DSD) Approaches on Viral Suppression and Retention in Care among Adolescents Aged 10-19 Living with HIV in Masaka Region, Uganda
REFNo: HS6682ES

1.Determine the impact of the DSD approaches on viral suppression and retention in care among adolescents aged 10-19 living with HIV in the Masaka region. 2.Explore mechanisms and pathways through which DSD approaches have impacted (or not) viral suppression and retention in care among adolescents aged 10-19 years living with HIV in the Masaka region and the contextual factors that influence these pathways. 3.Estimate the incremental cost-effectiveness of DSD approaches on viral suppression and retention in care among adolescents aged 10-19 years living with HIV in Masaka region.
 Uganda 2025-11-13 17:13:46 2028-11-13 Medical and Health Sciences Non-Clinical Trial Degree Award
JULIET ANENA
ID: UNCST-2025-R022055
 Monitoring the Diversity and Metabolic Shift of Gut Microbes during Fermented Cassava Feeding in an in Vitro Human Colonic Model
REFNo: A667ES

i. To assess the microbial population dynamics during anaerobic fermentation of cassava tubers
ii. To analyse the physicochemical properties and nutrient bioavailability of anaerobically fermented cassava flour
iii. To evaluate the effect of fermented cassava on gut microbial population, diversity, and microbial metabolites

 Uganda 2025-11-13 17:10:56 2028-11-13 Agricultural Sciences Non-Clinical Trial Degree Award
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