Ilemobayo Fasogbon Victor
ID: UNCST-2023-R008569
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DEVELOPMENT AND EVALUATION OF AN APTAMER-BASED LATERAL FLOW BIOSENSOR FOR RAPID DETECTION OF Mycoplasma bovis P48 PROTEIN
REFNo: HS4931ES
Evaluation of the aptamer-based biosensor using M. bovis infected milk samples,Construction of the aptamer-based biosensor after optimizing the inherent conditions and components,Characterization of the binding affinity and specificity of the aptamer-target interactions,Selection and optimization of the most sensitive aptamer for application in the lateral flow biosensor through molecular interaction studies on previously reported P48 protein aptamers.,he research aim to develop and evaluate an aptamer-based lateral flow biosensor for the rapid and accurate detection of the Mycoplasma bovis P48 protein in infected samples,
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Nigeria |
2024-12-23 12:36:24 |
2027-12-23 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
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Paul Matovu
ID: UNCST-2024-R004929
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The Phylogeny of East African Chlorophytum Ker-Gawl. (Asparagaceae), Phylogeography and Conservation of species found in Uganda
REFNo: NS756ES
1. To establish the phylogeny of Chlorophytum species in the FTEA region and put them in a global context.
2. To unravel the phylogenetic and morphological delimitation of problematic taxa and species complexes within Chlorophytum.
3. To establish the spatial phylogeny of Chlorophytum species that occur in Uganda
4. To establish the conservation status of Chlorophytum species in Uganda
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Uganda |
2024-12-23 12:34:57 |
2027-12-23 |
Natural Sciences |
Non-Clinical Trial |
Degree Award |
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Francis Ssali
ID: UNCST-2021-R012134
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A5409: A Phase 2 Randomized, Adaptive, Dose-Ranging, Open-Label Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis (RAD-TB)
REFNo: HS4036ES
1.2 Primary Objectives
1.2.1 To compare MGIT liquid culture TTP slope over the first 6 weeks of treatment for each experimental treatment arm to the SOC arm.
1.2.2 To compare new Grade 3 or higher adverse events (AEs) (safety) over the first 8 weeks of treatment for each experimental treatment arm to the SOC arm.
1.3 Secondary Objectives
1.3.1 To compare time to stable culture conversion by MGIT liquid culture by week 8 for each experimental treatment arm to the SOC arm.
1.3.2 To compare MGIT liquid culture TTP slope over the first 8 weeks of treatment for each experimental treatment arm to the SOC arm.
1.3.3 To compare new Grade 3 or higher AEs (safety) over 26 weeks of treatment for each experimental treatment arm to the SOC arm.
1.3.4 To compare discontinuations of anti-TB drugs for any reason prior to 8 and 26 weeks of treatment for each experimental treatment arm to the SOC arm.
1.3.5 To determine the dose- and exposure-response relationships between experimental drug estimated pharmacokinetic (PK) parameters with safety and efficacy.
1.3.6 To compare a composite of efficacy and safety outcomes using a risk-benefit approach for each experimental treatment arm to the SOC arm.
1.3.7 To compare MGIT liquid culture TTP slope over the first 6 weeks of treatment for Arms 3A-3B and Arms 4A-4B compared to Arm 2.
1.3.8 To compare durable cure by 52 weeks after treatment initiation in each experimental treatment arm to the SOC arm.
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Uganda |
2024-12-23 12:34:14 |
2027-12-23 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
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Hakimu Sseviiri
ID: UNCST-2024-R004881
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Formalizing and Elevating Workforce Visibility for Marginalized Sanitation Workers in Kampala, Uganda: Unravelling the intended and Unintended Consequences.
REFNo: SS2816ES
4. To co-design multi-stakeholder pathways towards effective formalization, integration and recognition of sanitation workers. ,3. To analyze the multi-dimensional intended and unintended impacts of formalizing and increasing the visibility of the workforce for the most marginalized workers. ,2. To identify and characterize actors involved in the formalization and visibility raising processes in Kampala city. ,1.To determine the different sanitation workers’ formalization and visibility raising initiatives overtime. ,To unravel the intended and unintended consequences of sanitation workers formalization and visibility enrichment in Kampala city, Uganda. ,
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Uganda |
2024-12-23 12:29:36 |
2027-12-23 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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George Alaneme Uwadiegwu
ID: UNCST-2024-R003261
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ARTIFICIAL INTELLIGENCE PREDICTIVE MODELLING OF MECHANICAL AND RHEOLOGICAL PROPERTIES OF GEOPOLYMER-CONCRETE MADE FROM BLENDED BAGASSE AND BANANA-PEEL-ASH
REFNo: SIR365ES
i. To characterize Bagasse ash (BA) and Banana peel ash (BPA) as a geopolymer precursor
ii. To ascertain the optimal combination of the concrete mixture incorporating Bagasse ash (BA) and Banana peel ash (BPA) to replace ordinary Portland cement.
iii. To determine the mechanical and rheological properties of Bagasse ash (BA) and Banana peel ash (BPA) and blended geopolymer concrete matrix.
iv. To develop soft computing predictive models of ANN, GEP and ANFIS to explore the relationships between the Alkalis-activated binder blend and the rheological and mechanical strength response.
v. To compare and validate the models developed in (iv).
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Nigeria |
2024-12-23 12:28:18 |
2027-12-23 |
Engineering and Technology |
Non-Clinical Trial |
Degree Award |
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Sarah Wambete Namee
ID: UNCST-2024-R003551
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Effectiveness Of A Health Belief Model (HBM)-Based Educational Intervention On Tuberculosis (TB) Treatment Adherence Among Tb Patients In Two Hospitals In Kampala, Uganda: A Randomized Control Trial
REFNo: HS4558ES
To assess the effectiveness of a Health Belief Model (HBM)-based educational intervention on TB treatment Adherence level among TB patients in two hospitals in Kampala, Uganda.
1.To assess the level of TB knowledge among TB patients in two hospitals in Kampala, Uganda.
2.To assess the health beliefs of TB patients towards tuberculosis in two hospitals in Kampala, Uganda
3.To assess the quality of life of TB patients in two hospitals in Kampala, Uganda.
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Uganda |
2024-12-23 12:26:18 |
2027-12-23 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Christine Piloya Ruth
ID: UNCST-2024-R003592
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Patriarchy and Women Engagement in Environmental Conservation in Northern Uganda: A Case of Gulu District
REFNo: SS2986ES
4. To propose a framework or a model for effective engagement of women in environmental conservation in patriarchal societies.,3. To establish the effectiveness of the strategies used by stakeholders in fostering women’s engagement in environmental conservation within a patriarchal setting in Gulu district.,2. To investigate the extent to which the distinguishing features of patriarchy affect women’s engagement in environmental conservation in Gulu district.,1. To examine in context, the socio-cultural roles performed by women in environmental conservation within the patriarchal structure in Gulu district. ,To examine the extent to which patriarchy affects women\'s engagement in environmental conservation in Gulu district.,
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Uganda |
2024-12-23 12:24:42 |
2027-12-23 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
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Henry Mugerwa
ID: UNCST-2019-R000420
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A Phase 1b, Age De-Escalation/Dose Escalation Trial to Evaluate Safety, Tolerability, and Pharmacokinetics of MAM01 in an African Population of Adults and Children in a Setting of Perennial Malaria Transmission
REFNo: HS5298ES
Primary Objective.
To assess the safety and tolerability of MAM01.
Secondary Objectives.
To assess the safety of MAM01.
To characterize the PK of MAM01 following SC, IV, and IM administration of MAM01.
To assess the formation of anti-drug antibodies (ADAs) to MAM01.
Exploratory Objectives.
To assess the protective efficacy of a single dose of MAM01 over 182 days against Pf infection, as detected by blood smear microscopy compared to a placebo.
To assess the protective efficacy of a single dose of MAM01 over 182 days against Pf infection, as detected by blood smear microscopy compared to placebo.
To assess the protection of MAM01 against events of malaria illness (first/only and all episodes).
To correlate MAM01 concentration with Pf infection risk.
To assess the complexity of Pf infection following administration of MAM01 or placebo.
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Uganda |
2024-12-23 12:23:27 |
2027-12-23 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
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Eleanor Namusoke Magongo
ID: UNCST-2021-R013199
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Outcome Evaluation of the Young People and Adolescent Peer Support (YAPS) program Implementation in Uganda
REFNo: HS4809ES
1. To assess fidelity of the YAPS program implementation by different stakeholders (MoH, Implementing Partners, Districts, Facilities, and YAPS personnel)
2. To establish the effect of the YAPS program on the clinical cascade for Adolescents and Young People Living with HIV.
3. To explore perspectives of YAPS and other stakeholders on the effectiveness of the YAPS program.
4. To estimate the incremental costs of implementing the YAPS model at the different levels of implementation (National, District and health facility)
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Uganda |
2024-12-23 12:17:40 |
2027-12-23 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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DANLADI MAKERI
ID: UNCST-2024-R005300
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Characterization of Staphylococcus aureus Isolated from Foot Ulcers of Diabetic Patients Attending Kampala International University Teaching Hospital, Bushenyi District, Uganda
REFNo: HS4836ES
v. To determine the molecular phylogeny of Staphylococcus aureus isolated from foot ulcers of Diabetic patients attending Kampala International University Teaching Hospital Bushenyi district, Uganda,iv. To determine the antibiogram profile of Staphylococcus aureus isolated from foot ulcers of Diabetic patients attending Kampala International University Teaching Hospital Bushenyi district, Uganda,iii. To assess the phenotypic distribution of Staphylococcus aureus in foot ulcers of Diabetic patients attending Kampala International University Teaching Hospital Bushenyi district, Uganda.,ii. To determine factors associated with diabetic foot infections among Diabetic patients with foot ulcers attending Kampala International University Teaching Hospital Bushenyi district, Uganda ,i. To determine the prevalence of diabetic foot infection among Diabetic patients with foot ulcers attending Kampala International University Teaching Hospital Bushenyi district, Uganda,To characterize Staphylococcus aureus isolated from foot ulcers of Diabetic patients attending Kampala International University Teaching Hospital Bushenyi district, Uganda ,
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Nigeria |
2024-12-23 12:15:59 |
2027-12-23 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
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