Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Yahaya Gavamukulya
ID: UNCST-2019-R001017
 Formulation and Pre-clinical Evaluation of Herbal Toothpaste/ Mouth Wash for Management of Oral Diseases: STI-OP Dental Solutions Project
REFNo: HS4022ES

General objective/ Purpose of the study To formulate a herbal toothpaste/ mouth wash and undertake preclinical studies on its use in management of oral diseases Specific objectives 1. To formulate herbal toothpaste/ mouth wash from extracts of selected plants for management of oral diseases. 2. To evaluate the organoleptic and physical properties of the formulated herbal toothpaste / mouth wash as per specified standards. 3. To evaluate the antimicrobial activity of the formulated herbal remedy against selected oral pathogens, Streptococcus mutans and Staphylococcus aureus. 4. To produce one batch of the fully tested herbal remedy for subsequent field testing.
Uganda 2024-04-22 6:35:14 2027-04-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Michael Okot
ID: UNCST-2023-R005793
 FACTORS INFLUENCING ACCESS AND UTILISATION OF ELIMINATION OF MOTHER TO CHILD TRASMISSION (EMTCT) OF HIV SERVICES IN ACHOLI SUB REGION, UGANDA.
REFNo: HS3996ES

To determine the enabling factors affecting access and utilization of the EMTCT services by the pregnant and breastfeeding women in Acholi Sub Region, Uganda.,To identify the predisposing factors affecting access and utilization of the EMTCT services by the pregnant and breastfeeding women in Acholi Sub Region, Uganda.,To explore and analyses the factors influencing the access and utilisation of the EMTCT services by pregnant women including those in high-risk groups in Acholi Sub Region.,
 Uganda 2024-04-22 6:25:27 2027-04-22 Medical and Health Sciences Non-Clinical Trial Degree Award
Justine  Komunyena Tumusiime
ID: UNCST-2023-R008465
 STAKEHOLDER ACCEPTABILITY AND USABILITY OF A MICROARRAY PATCH FOR PEDIATRIC ANTIRETROVIRAL TREATMENT IN UGANDA
REFNo: HS3928ES

To observe and interview stakeholders who would be potential users of the pediatric ARV MAP in Uganda
 Uganda 2024-04-22 6:21:28 2027-04-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Fred Ssewamala
ID: UNCST-2020-R014060
 Bridges2Scale: Testing Implementation Strategies for an intervention among young people affected by AIDS
REFNo: SS2488ES

Bridges2Scale will use a two-arm Hybrid III effectiveness-implementation cluster randomized clinical trial, where we will compare two multifaceted strategies (standard vs. enhanced) for scaling the Bridges interventions (consisting of financial literacy training, peer mentorship, family income-generating , and youth development accounts). The standard implementation strategy has been applied in our prior and ongoing studies and involves educational meetings that prepare staff members to deliver Bridges with minimal disruption to site workflow. This will be compared to an enhanced strategy that will be developed using Implementation Mapping, a systematic protocol for developing implementation strategies using theory, evidence, and stakeholder input. Aim 1: Compare the implementation effectiveness of the standard implementation strategy vs. an enhanced implementation strategy. Aim 2: Determine the clinical effectiveness of Bridges implemented via a standard vs. enhanced implementation strategy. Aim 3: Explore implementation processes, mechanisms, and determinants. Aim 4: Compare the cost and cost-effectiveness of the two implementation strategies.
 Uganda 2024-04-19 18:42:54 2027-04-19 Social Science and Humanities Clinical Trial Non-degree Award
Margaux Dupuis
ID:
Assessing the Role of Maternal Social Network Inheritance in the Social Integration of Juvenile Vervet Monkeys (Chlorocebus pygerythrus)
REFNo: NS802ES

I aim to answer the questions: how do maternal dominance rank, age, social network position, and mother-offspring proximity relate to the proximity and grooming networks of their juveniles? Does this differ by offspring sex and/or age?
I hypothesized that maternal social network inheritance occurs and differs by sex and age in vervet monkeys because of (1) mother-offspring proximity, (2) influences of maternal dominance rank and age, (3) patterns of youngest ascendency of female dominance rank in vervets, and (4) female philopatry.
 France 2024-04-19 18:38:19 2027-04-19 Natural Sciences Non-Clinical Trial Degree Award
Rhona Mijumbi M
ID: UNCST-2023-R006843
 Regional Hub for Knowledge Translation and Evidence-Informed and Equity-Centred Policymaking in Africa
REFNo: SS2454ES

To assess the impact of cross-country co-created evidence products on the policy making process in the individual countries affected by the same policy challenge,To assess the impact of participation in the regional hub on the development and pilot of new strategies for EIDM,To assess the context specific factors that impact success of a regional hub to support peer-to-peer learning and co-creation in EIDM,To assess the different institutions’ readiness to collaborate in a regional hub to foster cross-institutional peer-to-peer learning for EIDM,To study the impact of a regional hub designed to facilitate cross-institutional peer-to-peer learning on innovative strategies aimed at bolstering evidence-to-policy in priority SDGs in Uganda, Tanzania, Ethiopia, and Malawi. The priority SDGs we shall use for this study are reproductive health and clean energy.,
 Uganda 2024-04-19 18:36:13 2027-04-19 Social Science and Humanities Non-Clinical Trial Non-degree Award
Godfrey Ejuu
ID: UNCST-2021-R013978
 PLAYFUL FUTURES: A RANDOMIZED CONTROL TRIAL OF EARLY CHILDHOOD CARE AND EDUCATION TEACHER TRAINING AND MENTORSHIP IN UGANDA
REFNo: SS1634ES

Overall aim and outcome
The overall goal of the project is “Children improve literacy, numeracy skills and develop socio emotional skills through Learning through Play.
Main research question
To what extent does the ECCE intervention improve quality and sustained learning through play and holistic development among children 3-6 years in centre based learning environments?

Specific research questions
Aim one: To improve quality of the ECCE learning environment for children three-to-six years old
Research questions:
• What is the effect of the LtP intervention on teaching practices, learning environment and development of holistic skills of children three-to-six years from ECCE centers? Is there a difference in outcomes between boys and girls?
Aim two: To improve educators’ instructional practice and implement Learning through Play activities
Research questions:
• What is the effect of LtP mentorship on pedagogical skills in ECCE classrooms? Does this differ by sex of educators?
• What is the effect of the Playful Futures LtP intervention package on pedagogical skills in ECCE classrooms?
Aim three: Coordinating Centre Tutors (CCTs) provide useful, recurrent and effective guidance to educators on LtP
Research questions:
• To what extent does Playful Futures intervention encourage effective and regular mentorship to ECCE educators in support of LtP?
Aim four: Key stakeholders have improved knowledge, attitudes and practices, and abilities to introduce and promote learning through play, including educators, parents, government officials, and community leaders
Research questions:

Research questions:
• What is the effect of playful futures intervention in improving attitudes and practices of parents and community members regarding LtP?
• How does Playful Futures influence parents’ involvement on play activities at home?

 Uganda 2024-04-19 18:24:07 2027-04-19 Social Science and Humanities Non-Clinical Trial Non-degree Award
ABRAHAM OGWAL
ID: UNCST-2020-R014262
 Thermo-Physical Characterization of Briquettes from Maize cobs and Rice husks in Kole District, Northern Uganda
REFNo: NS457ES

(i). To determine proximate composition of briquette samples produced from blended maize cobs and rice husks.
(ii). To evaluate the efficiency of briquette samples produced from blended maize cobs and rice husks.
(iii). To determine gaseous and black carbon emissions level of briquette samples blended from maize cobs and rice husks.

Uganda 2024-04-19 18:10:37 2027-04-19 Natural Sciences Non-Clinical Trial Degree Award
HENRY KATAMBA STANLEY
ID: UNCST-2024-R004704
 A model to improve the adoption, utilisation and sustainability of digital health initiatives by health workers in Uganda.
REFNo: HS4013ES

The purpose of this study will be to investigate the factors that are barriers to improve performance of electronic health management information systems despite adoption of digital health initiatives in health facilities at Uganda and to develop an integrated support model to improve the adoption and sustainability in the utilisation of digital health initiatives and to strengthen performance of electronic health management information systems by health workers in health facilities at Uganda. ,
 Uganda 2024-04-18 13:34:22 2027-04-18 Medical and Health Sciences Non-Clinical Trial Degree Award
Baker  Lukwago
ID:
Optimizing Journey Mapping Techniques: Innovating Methods to Better Understand Pregnancy Journeys for Women Living in Uganda Version 1.2 February 2024
REFNo: HS4024ES

 Objective 2.b: Document women’s experience (satisfaction/dissatisfaction) with digital engagement touchpoints along the pregnancy care-seeking decision pathway, noting differences between urban and rural settings. , Objective 2.a: Determine the potential of remote data collection to capture key pregnancy care-seeking decisions, (attendance of ANC, referral for conditions/ complications, and childbirth experience) including barriers, facilitators and influencers at decision-making point, noting differences between urban and rural settings; gather data on health expenditure at each pregnancy care-seeking pathway point; and capturing quality of maternal care and client experience data,Phase 2- Objective 1: Investigate how remote engagement mechanisms can be used to collect consumer insights more frequently (relative to traditional journey mapping), Objective 1.c: Explore women’s preferences for future digital engagement touchpoints along the pregnancy care-seeking and primary care decision pathway, noting differences between urban and rural settings., Objective 1.b: Describe the quality of maternal care and client experience, disaggregated by urban and rural settings., Objective 1.a: Describe key pregnancy care-seeking decisions, (attendance of ANC, referral for conditions and complications, childbirth experience, follow-up health visits in the post-partum period) including barriers, facilitators, and influencers at decision-making points, noting differences between urban and rural settings and previous pregnancy care experience. ,Phase 1-Objective 1: Use traditional journey mapping techniques to describe the pregnancy care-seeking pathway of women who gave birth in urban and rural settings of Uganda ,
 Uganda 2024-04-18 13:27:52 2027-04-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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