Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Joseph Ngonzi
ID: UNCST-2019-R001579
 Smart Discharges for Mom & Baby: A cohort study to develop prognostic algorithms for post-discharge readmission and mortality among mother-infant dyads..
REFNo: HS2174ES

To identify gaps and opportunities during in-hospital, discharge, and post-discharge care to inform the future development of an evidence-and risk-based bundle of interventions to improve postnatal care (PNC) for dyads.,To inform the development of an integrated maternal and newborn risk-based post-discharge care program.,To develop and internally validate clinical risk prediction models for identifying dyads at high-risk of death or hospital readmission in the 6 week post-delivery post-discharge period.,
 Uganda 2022-04-07 2025-04-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Annet Nakaganda
ID:
Vaginal stenosis in patients treated with Radiotherapy for cancer of the cervix in Uganda
REFNo: HS2150ES

To assess the incidence, risk factors and clinical manifestation(s), of radiation-induced vaginal stenosis in patients with cancer of the cervix at Uganda Cancer Institute.
 Uganda 2022-04-07 2025-04-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ronald Arineitwe Kibonire Arineitwe Kibonire
ID:
Strategies to enhance indigenous men’s support for utilisation of long-acting reversible contraceptives amongst rural women in Uganda
REFNo: HS2152ES

The objective of this study is to:

•Explore and describe the perceptions of rural indigenous Ugandan men regarding the use of LARCs.

•Understand the belief systems that rural indigenous Ugandan men have regarding the use of LARCs

•Develop strategies to enhance indigenous Ugandan men’s support for utilisation of LARCs amongst rural women in Uganda

 Uganda 2022-04-07 2025-04-07 Medical and Health Sciences Non-Clinical Trial Degree Award
Susan  Nabadda Ndidde
ID: UNCST-2020-R014331
 A Study to Improve Understanding of Viral Load Suppression in Children Living with HIV in Uganda.
REFNo: HS2188ES

To establish factors associated with viral load suppression in children 0-14 years using the LIMS.,To determine the extent to which viral load suppression rates differ by demographic characteristics (age group, ART regimen, duration on ART, and region) using Laboratory Management Information System (LIMS) data.,To determine the trends in paediatric (0-14years) viral load suppression rates from 2016 to 2020.,To determine the proportion of children aged 0-14 years living with HIV that underwent a viral load test in 2016, 2017, 2018, 2019 and 2020 and are virally suppressed.,
 Uganda 2022-04-07 2025-04-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Hellen Nabayiga
ID: UNCST-2022-R011299
 modelling the antibiotic supply chain. A case of Uganda
REFNo: SS1240ES

To develop an understanding of appropriate antibiotic availability in Uganda public health facilities
 Uganda 2022-04-07 2025-04-07 Social Science and Humanities Non-Clinical Trial Degree Award
Emmy Okello
ID: UNCST-2020-R009792
 Investigating the Relationship of Low-HDL as a Risk Factor for Development of Rheumatic Heart Disease
REFNo: HS2085ES

General Objective;
The objective of this project is to explore the relationship between Rheumatic Heart Disease (RHD) and high-density lipoprotein cholesterol (HDL-c) levels in a high risk pediatric population in Uganda.

Specific Objectives;
1)To evaluate whether or not low HDL-c is associated with the diagnosis of RHD.

2)To evaluate whether a lower HDL-c level is associated with more severe RHD.

 Uganda 2022-04-04 2025-04-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Frank Kutensa
ID:
Health care workers\' and mothers\' perspectives on the experiences and challenges with maternal health care services in rural areas of Uganda during the COVID-19 pandemic. A qualitative study.
REFNo: HS2134ES

1. To explore the mothers’ experiences and challenges with utilization of maternal health care services during COVID-19.

2. To explore health care providers’ perspectives and challenges regarding the delivery and mothers’ use of maternal health care services during COVID-19
 Uganda 2022-04-04 2025-04-04 Medical and Health Sciences Non-Clinical Trial Degree Award
twinamasiko nelson
ID: UNCST-2021-R013346
 MULTIDRUG RESISTANT BACTERIA CONTAMINATION OF CLINICAL ATTIRE OF MEDICAL DOCTORS IN MULAGO NATIONAL REFERRAL HOSPITAL.
REFNo: HS2177ES

Primary objective
1. To determine the prevalence of pathogenic bacteria on clinical attires of medical doctors in Mulago National referral hospital.
Secondary Objectives
1. To determine the prevalence of multidrug resistant bacteria on clinical attires of medical doctors in Mulago National referral hospital.
2. To determine the level of knowledge and attitudes on IPC among medical doctors in Mulago National referral hospital.
3. To determine the level of practice of IPC measures among medical doctors in Mulago National referral hospital.

 Uganda 2022-04-04 2025-04-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Damian Kajunguri
ID:
Assessing the effectiveness of alternative science education teaching methods during and after COVID-19 lockdown in Kigezi region, Western Uganda
REFNo: SS928ES

The main objective of the research is to determine how the different learning approaches impacted science education during and after COVID-19 induced lockdown. The specific objectives are to: i) Establish the type and extent of coverage of the science-based learning that took place during and after lockdown. ii) Determine how practical aspects were handled in the alternative learning processes that were provided during and after lockdown. iii) Ascertain the uniformity of syllabus coverage of science subjects before-during- and after lockdown. iv) Assess students’ responses towards the various science-based learning processes during and after lockdown in respect of gender, age groups and school status.
 Uganda 2022-04-02 2025-04-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Andrew Michael Mutyaba
ID:
The Politics of Uganda's Refugee Policy
REFNo: SS1066ES

To investigate the political economy of the relationship between Uganda's refugee policy and its political system
To understand the needs, incentives and logics behind Uganda's liberal refugee policy
To examine how liberal Uganda's refugee policy is, compared with her neighbours Rwanda, Tanzania and Kenya
To explore the constraints that politic imposes upon the implementation of Uganda's refugee policy in the context of decentralisation
 Uganda 2022-04-02 2025-04-02 Social Science and Humanities Non-Clinical Trial Degree Award
Miriam Nakalembe
ID: UNCST-2021-R014040
 Simplified Treatment for Eclampsia Prevention using Magnesium sulfate: A phase III, randomized, open label, active controlled, multicountry, multicentre, non-inferiority trial of simplified magnesium sulfate regimen for eclampsia prophylaxis (The STEP-Mag Trial).
REFNo: HS2076ES

The primary objective of this trial is to evaluate non-inferiority of magnesium sulfate 10g IM administered 12 hourly x 2 doses compared with a standard IV (Zuspan) or IM (Pritchard) magnesium sulfate regimen1 in the prevention of maternal eclamptic seizure.

The secondary objective of this trial is to evaluate superiority of magnesium sulfate 10g IM administered 12 hourly x 2 doses compared with a standard IV (Zuspan) or IM (Pritchard) magnesium sulfate regimen in the proportion of women experiencing adverse events indicative of magnesium toxicity.
 Uganda 2022-04-02 2025-04-02 Medical and Health Sciences Clinical Trial Non-degree Award
Patrick OJOK
ID:
Exploratory study on the implementation Status of inclusive education policies in Uganda
REFNo: SS1202ES

4. Identify and document best practices and lessons that can be up-scaled to improve the implementation of inclusive education in Uganda and at the sub-regional level (EAC). ,3. Explore the perceptions of education stakeholders in Uganda towards inclusive education and the appropriate model for implementing inclusive education.,2. Explore the facilitators and barriers to implementing inclusive education policies in Uganda.,1. Determine the implementation status of existing inclusive education policies in Uganda.,The purpose of the proposed study is to ascertain the implementation status of inclusive education policies in Uganda, explore the factors that influence their implementation and document best practices and lessons to reinvigorate inclusive education at a sub-regional level.,
 Uganda 2022-04-02 2025-04-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Lydia Nakiyingi
ID:
Exploring immune mechanisms among persons with MTB infection or TB disease, compared to no MTB infection in an endemic setting
REFNo: HS2125ES

General objective:
•To understand the immune mechanisms that underlie TB infection and TB disease compared to those with neither state in an MTB endemic setting using samples collected from individuals with either latent or active TB infection and those without-MTB infection for comparison.
Specific objectives:
• To define the immunological mechanism(s) in MTB using samples from individuals with latent infection, active TB or no MTB infection.
•To identify correlates of immune protection against TB infection and disease in adults in high TB endemic settings; an important pre-requisite in responses to newer TB vaccines
•To compare genetic sequences between adults with active TB, latent TB and no MTB infection in order to delineate genetic mechanisms of protection or disease

 Uganda 2022-04-02 2025-04-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Teddy Nakubulwa
ID:
Sexual and Reproductive Health and Economic Empowerment –Supporting Out-of-school Adolescent girls’ Rights and Skills (SHE SOARS) Program
REFNo: SS1225ES

4) Identify programmatic priorities and approaches through key informant interviews with stakeholders such as government staff, community leaders, health care providers and staff from other sexual reproductive health rights projects.,3) Contribute to the evidence base surrounding Gender Equality and Sexual Reproductive Health outcomes for adolescent s through documenting evidences of how the project is rendering effective, relevant, efficient and sustainable solutions to target project participants. ,2) Examine the current knowledge, attitudes and practices related to sexual reproductive health and gender equality among adolescents, particularly out-of-school adolescents, to inform project implementation ,1) Establish baseline, mid term and endline values for all indicators for the SHE SOARS project.,
 Uganda 2022-04-02 2025-04-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ninsheka  Leonard
ID:
Analysis of the Effects of the Forms and Drivers of Urban Agriculture on the socio-Economic Status of Farmers in Kampala and Mbarara Cities, Uganda
REFNo: A172ES

1) Examine the forms of urban agriculture on the socio-economic status of the urban farmers
in Kampala and Mbarara Cities.
2) Examine the Drivers of urban agriculture on the socio-economic status of the urban farmers
in Kampala and Mbarara Cities.
3) Establish appropriate policy directions of urban agriculture on the socio-economic status
of urban farmers in Kampala and Mbarara Cities.
4) To establish the influence of socio-demographic characteristics on the socio-economic
status of urban farmers in Kampala and Mbarara Cities

 Uganda 2022-04-01 2025-04-01 Agricultural Sciences Non-Clinical Trial Degree Award
Alinda  Fred
ID:
ADVANCING AGRICULTURAL INSURANCE IN UGANDA’S CLIMATE CHANGE ADAPTATION: DETERMINANTS AND STRATEGIES FOR INSURANCE UPTAKE
REFNo: A181ES

1. To assess the agricultural insurance positioned in the climate change adaptation framework for Uganda and what are the critical gaps
2. To assess the demand and supply side constraints to adoption of agricultural insurance in Uganda borrowing insights from empirical literature in other countries
3. To identify the existing strategies to promoting agricultural insurance as an overarching climate change adaptation strategy.
4. To identify strategies that Uganda can adapt to effectively promote agricultural insurance as a climate change adaptation strategy.

Uganda 2022-04-01 2025-04-01 Agricultural Sciences Non-Clinical Trial Degree Award
Alfred Jatho
ID: UNCST-2021-R011710
 Barriers to and Facilitators of Prostate Cancer Screening among Men in Uganda Prisons
REFNo: HS2128ES

The goal of this study is to examine the perceptions, attitudes and beliefs of men in Uganda Prisons regarding barriers to and facilitators of PCa screening. This will enable the research team to identify potential interventional strategies to promote PCa screening among men in Uganda prisons.,
 Uganda 2022-04-01 2025-04-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joaniter Nankabirwa Immaculate
ID: UNCST-2021-R012896
 Optimizing the use of SARS-Cov-2 antigen rapid diagnostic tests (Ag-RDT) for timely detection and effective response to COVID-19 in key border communities in Uganda
REFNo: HS2050ES

To evaluate the feasibility of active surveillance using the SARS-CoV-2 Ag-RDT in high-risk populations in border districts of Tororo and Busia.

To determine the yield of active surveillance using the SARS-CoV-2 Ag-RDT in high-risk populations in the border districts of Tororo and Busia districts

To assess the acceptability of active surveillance using the SARS-CoV-2 Ag-RDT in high-risk populations in border districts of Tororo and Busia.

 Uganda 2022-04-01 2025-04-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
helen harrison
ID:
A grounded theory epistemological exploration of wellbeing for women with lived experience of conflict-affected trauma, based in Uganda
REFNo: HS2148ES

- To use thematic-induced analysis to develop a theory relating to the epistemology of wellbeing that is grounded in the interview data,- To conduct semi-structured interviews with six – eight female participants from each of the communities.,- To explore the epistemology of wellbeing for women from three specific Uganda-based communities, each of whom has lived experience of conflict-affected trauma, and who are linked through trauma counselling,
 UK 2022-04-01 2025-04-01 Medical and Health Sciences Non-Clinical Trial Degree Award
Thereza Piloya Were
ID: UNCST-2019-R000491
 Diabetes in African Youth: Improving Glucose Time-In-Range (DAY Time) Randomized Clinical Trial.
REFNo: HS2129ES

Primary Study Objectives
1. To determine if patient ability to continuously observe plasma glucose levels for 6 months using a flash intermittently scanned CGM improves glucose TIR compared to baseline. The change in glucose TIR while wearing the unblinded CGM will be compared to change in TIR in patients performing 3x/day SMBG (wearing a blinded CGM for endpoint measurement).
2. To perform a cost analysis on flash glucose monitoring compared to 3x/day SMBG, to determine whether this technology is cost effective in the setting of a low-resource nation.
Secondary Objectives: To assess the change-from-baseline impact of unblinded CGM on:
1. Percent time-in-range at 12 months
2. Percent time with glucose 180-250, >250, <70, and <54 mg/dl at 6 and 12 months
3. HbA1c at 6 and 12 months
4. Patient satisfaction and quality of life at 6 and 12 months
5. Glucose variability (coefficient of variation, CV) at 6 and 12 months

 Uganda 2022-04-01 2025-04-01 Medical and Health Sciences Clinical Trial Non-degree Award
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