Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Alex  Muganzi Muganga
ID: UNCST-2019-R000710
Project Assessment Protocol for IDI Key Populations Civil Society Organizations Mechanism in Uganda
REFNo: SS4017ES

(2) Ensuring scale-up of effective, efficient and quality comprehensive HIV service delivery through key population Drop-in Centers (DICs). ,(1) Strengthening KP CSOs’ coordination capacity and improve governance including accountability, legitimacy, constituency and membership to support provision of layered comprehensive HIV/AIDS services,
Uganda 2025-07-22 17:00:53 2028-07-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ponsiano Ocama
ID: UNCST-2019-R000440
Leveraging HIV care infrastructure for implementation of context-adapted liver cancer comprehensive control strategies in Uganda: The LC3 Study
REFNo: HS6141ES

1) To adapt and plan integration of the Liver Cancer Comprehensive Control (LC3) package into the existing HIV infrastructure and care model. Using the Consolidated Framework for Implementation Research (CFIR), we will evaluate the local context for liver cancer control among PLWH. Guided by Dynamic Adaptation Process (DAP), we will work with key stakeholders to identify and adapt implementation strategies for LC3 package delivery. 2) To evaluate the integration of the LC3 package into the existing HIV infrastructure and care model using a phased implementation strategy. We will conduct a Type II hybrid observational implementation-effectiveness trial with phased implementation in six clinics in urban and rural Uganda. Using the RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) framework, the primary outcome will be increased reach of package services, with secondary outcomes including effectiveness of LC3 package in linking HBsAg-positive participants to referral care, measures of adoption, implementation (fidelity), and maintenance. 3) To identify contextual factors mediating successful integration of LC3 services into routine HIV care and maintenance/sustainability. We will use mixed-methods to identify and compare contextual elements at patient, provider, and clinic levels across high and low performing sites to inform iteration, transferability, and scale-up. We will also assess maintenance post-implementation at all six sites.
Uganda 2025-07-22 16:59:30 2028-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Maegan Hoffman Jennie
ID: UNCST-2025-R018963
Behavioral impact of variable terrain across wild chimpanzee populations
REFNo: SS3973ES

Determine whether difference in terrain, primarily elevation and slope, are significant predictors of the observable differences in social behavior seen
between the Kanyawara and Budongo chimpanzees.

USA 2025-07-22 16:56:59 2028-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
Dan Muramuzi
ID: UNCST-2023-R008225
Examining the implementation process of the Ugandan National Medical Oxygen Scale Up Plan of 2018-2022 within selected health facilities
REFNo: HS6032ES

To evaluate the extent of integrating oxygen indicators into the health management information system in Uganda.,To determine the extent to which the Uganda national oxygen scale-up plan 2018-2022 (and related policies) has been put into action.,To explore the stakeholder perspectives, power, influence and relationship towards the implementation of the national oxygen scale-up plan.,
Uganda 2025-07-22 16:55:42 2028-07-22 Medical and Health Sciences Non-Clinical Trial Degree Award
Lilian Nagawa
ID: UNCST-2025-R017226
Effect of Strategic Management Practices on Sustainable Growth of Small and Medium Enterprises in the Oil and Gas Sector in Uganda
REFNo: SS3672ES

The overall objective of this research is to examine the influence of strategic management practices on the sustainable growth of small and medium-sized enterprises providing goods and services to the oil and gas sector in Uganda
Specific Objectives
The study will seek to specifically achieve the following objectives:
i. To establish the effect of environmental scanning on the sustainable growth of SMEs providing goods and services to the oil and gas sector in Uganda
ii. To determine the relationship between strategy formulation and sustainable growth of SMEs providing goods and services to the oil and gas sector in Uganda.
iii. To establish the influence of strategy implementation on the sustainable growth of SMEs providing goods and services to the oil and gas sector in Uganda
iv. To establish the relationship between strategy evaluation and control and the sustainable growth of SMEs providing goods and services to the oil and gas sector in Uganda

Uganda 2025-07-22 16:54:02 2028-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
ELIZABETH ONAYEMI OCHIENG
ID: UNCST-2023-R006823
PROFESSIONAL DEVELOPMENT OF CORE SCIENCE TEACHERS AND ACADEMIC PERFORMANCE OF ORDINARY LEVEL SECONDARY STUDENTS IN CORE SCIENCE SUBJECTS IN SELECTED SECONDARY SCHOOLS IN CENTRAL UGANDA
REFNo: SS3607ES

i) To examine the effects of formal teacher professional development on the academic performance of O-Level students in core O Level science subjects in selected secondary schools in Central Uganda.

ii) To examine the effects of informal teacher professional development on the academic performance of O-Level students in core O Level science subjects in selected secondary schools in Central Uganda.

iii) To analyse the effectiveness of the different models of teacher professional development available to O-Level teachers of core science subjects in selected secondary schools in Central Uganda.

Kenya 2025-07-22 16:52:32 2028-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
Namara Grace
ID: UNCST-2023-R005711
RE: READING BANYAKORE POTS: NARRATIVES OF MARRIAGE POTS BY WOMEN AND POTTERS OF BIHARWE, MBARARA CITY WESTERN UGANDA
REFNo: SS3475ES

1. To establish the historical evolution that grounds the Banyakore marriage pots in the context of design and the associated traditions, norms and practices
2. To examine factors that influence meaning making of the Banyakore marriage pots among the people of Mbarara City, southwestern Uganda from its inception to the present day
3. To document the role and cultural relevance of the Banyakore marriage pots based on the narratives of Women and Potters of Mbarara City, Western Uganda

Uganda 2025-07-22 16:49:00 2028-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
Rita Nassanga
ID: UNCST-2020-R014686
USE OF BRAIN MAGNETIC RESONANCE IMAGING FOR DEMENTIA DIAGNOSIS IN UGANDA
REFNo: HS4777ES

1. To document information about the use of brain MRI for dementia in low- and middleincome countries based on a systematic review and meta-analysis from published literature. 2. To explore the perceptions and practices of imaging personnel and physicians in using brain MRI as a diagnostic approach for dementia in Uganda. 3. To describe the volume and structural changes in brain MRI of patients with a clinical diagnosis of Dementia. 4. To determine the agreement between brain MRI and the Mini Mental State Exam in the diagnosis of dementia. 5. To determine the effect of training of Radiology Senior House Officers and Radiologists on the brain MRI interpretation for patients with a clinical diagnosis of dementia.
Uganda 2025-07-22 16:39:18 2028-07-22 Medical and Health Sciences Non-Clinical Trial Degree Award
COMFORT ANKUNDA
ID: UNCST-2024-R004433
The Role of Sport in Social inclusion and integration in Sweden and Uganda
REFNo: SS3768ES

Objectives
The primary objective of the study is explore how sport facilitates or otherwise hinders social inclusion and integration especially for vulnerable children and youth including those with a migrant background, living in poor families or affected HIV/AIDS or other disasters. The study will explore the following questions:
1. How is social inclusion and integration understood and defined by the children, youth and staff in sport-based projects that contribute to social inclusion and integration and by other relevant actors and stakeholders?
2. How do the involved young people perceive and experience the sport-based projects that contribute to social inclusion and integration they participate in?
3. What enables or limits beneficiaries’ and leaders’ participation in the different levels of sport-based initiatives that contribute to social inclusion and integration?
4. What needs to be done to improve the active participation of children and youth in their own social inclusion and integration processes?

Sweden 2025-07-22 16:30:39 2028-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
Linda Adiru Atiku
ID: UNCST-2024-R015308
Laboratory-Based Surveillance for Eschar-Associated Rickettsial Infections in Uganda
REFNo: HS5142ES

1. To retrospectively identify any eschar swabs collected during January 1, 2021, through November 30, 2024 as part of routine anthrax surveillance that are positive for Rickettsia spp.
2. To prospectively identify any eschar swabs collected beginning December 1,2024 through December 31, 2025 as part of routine anthrax surveillance for diagnostic purposes that are positive for Rickettsia spp.
3. To describe the epidemiology of persons with rickettsial infection identified from eschar swabs collected for anthrax surveillance.

Uganda 2025-07-22 15:53:57 2028-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
OLIVERCAROLINE WOKALI
ID: UNCST-2025-R017008
Prevalence and factors associated with neurodevelopmental impairment among children with and without HIV from infancy to prepuberty at Mbarara: a multi-center study
REFNo: HS6174ES

1. To determine the prevalence of neurodevelopmental impairments among children with and without HIV 2. To determine the factors associated with neurodevelopmental impairments among children with and without HIV
Uganda 2025-07-22 15:52:51 2028-07-22 Medical and Health Sciences Non-Clinical Trial Degree Award
Reagan Suubi
ID: UNCST-2025-R018154
The Influence of Communication on Youth Engagement in Agripreneurship in Kamuli District, Uganda
REFNo: SS4050ES

Identify the different sources of agripreneurship information the youth agripreneur’s have access to.

Identify the types of agripreneurship information received by the youth in Kamuli district.  

Identify the different communication channels used by the youth in Kamuli district when receiving information.  

Explain the different challenges faced by youth when accessing information.  

Describe how the information received by the youth is being utilized in agripreneurship
Uganda 2025-07-22 15:45:40 2028-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
Esther Nduati Nyambura
ID: UNCST-2024-R002923
FACTORS ASSOCIATED WITH DELAYED TIME-TO-PRESENTATION AND OUTCOMES AMONG SEVERE TRAUMA PATIENTS ADMITTED TO MULAGO NATIONAL REFERRAL HOSPITAL EMERGENCY UNIT
REFNo: HS5557ES

This study aims to investigate the factors associated with delayed time-to-presentation to the emergency department and assess the outcomes of severe trauma patients admitted to Mulago National Referral Hospital (MNRH) Emergency Unit.
Kenya 2025-07-22 15:43:45 2028-07-22 Medical and Health Sciences Non-Clinical Trial Degree Award
Confidence  Nkurunungi Asiimwe
ID: UNCST-2024-R015200
Parent Alcohol Use, Harsh Parenting,Adolescent Alcohol Use and Mental Illness among Adolescents in Kabale District, Southwestern Uganda
REFNo: SS4070ES

1) To examine the association between parent alcohol use and harsh parenting.
2) To determine the association between parent alcohol use and adolescent mental illness.
3) To examine the association between harsh parenting and adolescent mental illness.
4) To find out the association between adolescent alcohol use and adolescent mental illness.
5) To find out whether adolescent alcohol use mediates the association between parent alcohol use, harsh parenting and mental illness.
6) To explore experiences of parents, teachers and opinion leaders in regard to parent alcohol use, harsh parenting, adolescent alcohol use and mental illness.

Uganda 2025-07-22 15:41:23 2028-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
Marion Birungi
ID: UNCST-2024-R016519
Barriers, Facilitators and Solutions towards Sustainability of Antimicrobial Stewardship Interventions in Selected Ugandan Hospitals. A multiple-methods study
REFNo: SS3741ES

1. To determine the AMS interventions implemented in six selected hospitals in Eastern and Central Uganda.
2. To explore barriers and facilitators of sustainability of AMS interventions in six selected hospitals in Eastern and Central Uganda.
3. To examine how attributes that contribute to sustainability were conceptualized and embedded in the implementation of AMS interventions in six selected hospitals in Eastern and Central Uganda.
4. To assess the sustainability capacity for AMS interventions in six selected hospitals in Eastern and Central Uganda.

Uganda 2025-07-22 15:25:28 2028-07-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
EVALUATING HIV EARLY INFANT DIAGNOSIS PERFORMANCE FOR THE ALINITY M HIV-1 ASSAY
REFNo: HS6246ES

1. The primary objective of this protocol is to evaluate the concordance of the Alinity m HIV-1 assay with the cobas HIV-1/HIV-2 Qualitative nucleic acid test for use on the cobas 6800/8800 for early infant diagnosis. The percent agreement will be assessed.
2. The secondary objective is to validate the use of the investigational Alinity m DBS EID Supplement to Alinity m HIV-1 assay using. Specifically, the percent agreement compared to cobas HIV-1/HIV-2 Qualitative nucleic acid test for use on the cobas 6800/8800 will be determined.

Uganda 2025-07-22 15:23:01 2028-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
bwesigye thaddeus
ID: UNCST-2025-R017892
Anti-cancer activity of selected medicinal plant species in Kigezi Sub Region of Uganda used by Herbalists
REFNo: NS953ES

i. Identify the medicinal plants species in Kigezi used by herbalists for cancer management in order to document them. ii. Evaluate the effect of the medicinal plants’ extracts used by herbalists on human cancer cell lines in order to determine their cytotoxicity. iii. Evaluate the isolated phytochemical compounds from the anticancer medicinal plant extracts for antioxidant potential to determine their cytotoxic effect on human cancer cell lines. iv. Investigate the cytotoxic effect of phytochemical compounds from the anticancer medicinal plants on human cell lines so as to determine their mechanism of cell death.
Uganda 2025-07-22 15:08:53 2028-07-22 Natural Sciences Non-Clinical Trial Degree Award
LIVINGSTONE MAKANGA KYEGOMBE
ID: UNCST-2024-R015296
Maternal and perinatal death surveillance and response: Analysis of the processes, factors and challenges of implementation in refugee-hosting districts of west Nile, Uganda
REFNo: HS5996ES

3) To explore the perceptions of stakeholders (including refugees and nationals) on the processes and challenges of implementing MPDSR in refugee-hosting districts of the west Nile region. ,2) To assess factors that influence the implementation of maternal death surveillance and response in Adjumani and Yumbe refugee-hosting districts of west Nile.,1) To assess the processes of implementation of maternal and perinatal death surveillance and response in Adjumani and Yumbe refugee-hosting districts of west Nile. ,To investigate the processes, factors, and challenges of implementation of maternal and perinatal death surveillance and response (MPDSR) in refugee-hosting districts of west -Nile,
Uganda 2025-07-22 15:07:21 2028-07-22 Medical and Health Sciences Non-Clinical Trial Degree Award
Joannah Nalwoga
ID: UNCST-2024-R002651
PREVALENCE AND FACTORS ASSOCIATED WITH OFFERING POST-PARTUM CONTRACEPTION BY HEALTHCARE WORKERS IN KAYUNGA DISTRICT: A CROSS-SECTIONAL STUDY
REFNo: HS6011ES

III. To establish the healthcare facility-related factors associated with using Postpartum contraception in Kayunga District,II. To document the individual-related factors (Knowledge, attitudes, practices) of healthcare workers associated with the use of Postpartum contraception among mothers in Kayunga District.,I. To determine the prevalence of the use of Postpartum contraception among mothers in Kayunga District.,
Uganda 2025-07-22 15:05:22 2028-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sophia Nakitto
ID: UNCST-2024-R002921
Prevalence and treatment outcomes of children below 15 years with severe malaria hemoglobinuria, a retrospective study at Kayunga regional referral hospital.
REFNo: HS6156ES

To determine the prevalence of severe malaria among children below 15 years admitted at Kayunga regional referral hospital. To determine the prevalence of severe malaria with hemoglobinuria among children below 15 years admitted at Kayunga regional referral hospital. To identify the factors associated with severe malaria with hemoglobinuria among children below15 years admitted with severe malaria at Kayunga regional referral hospital. To determine the immediate outcomes among children below 15 years managed for severe malaria with haemoglobinuria.
Uganda 2025-07-18 14:52:41 2028-07-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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