Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Nanyonga Elizabeth
ID: UNCST-2025-R018232
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REFNo: SIR516ES

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 Uganda 2025-05-27 9:30:38 2028-05-27 Engineering and Technology Clinical Trial Non-degree Award
Justine  Komunyena Tumusiime
ID: UNCST-2023-R008465
 “Exploring Acceptability: Expanding Family Planning Services in Pharmacies and drug shops in Uganda.”
REFNo: HS5733ES

a. To assess the acceptability of family planning including implant provision through pharmacies and drug shops among key stakeholders in Uganda.
b. To examine the role of non-monetary incentives (e.g., training, certification, recognition) in motivating pharmacy and drug shop operators to provide FP services.
c. To explore the willingness and capacity of pharmacy and drug shop providers to comply with government reporting requirements for FP service provision.
d. To identify perceived potential facilitators and challenges to the successful implementation of implant provision in pharmacies and drug shops in Uganda.

 Uganda 2025-05-27 11:03:29 2028-05-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Martina Ferracane Francesca
ID: UNCST-2025-R016796
 Assessing the digital trade rules in Rwanda and Uganda
REFNo: SS3942ES

Main Objective 1. Address the knowledge gap between Uganda’s current legal framework and its potential enabling or restrictive impact on digital trade development, ensuring that policy initiatives and policy framework align with the needs of businesses engaging in digital trade. Specific Objectives 1. Identify the challenges faced by private sector entities, including SMEs and start-ups, in digital trade. 2. Provide actionable policy recommendations to improve Uganda’s digital trade framework. 3. Assess the existing digital trade policies in Uganda and identify areas for improvement.
 Italy 2025-05-23 8:20:18 2028-05-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Stephen Lwasa
ID: UNCST-2025-R018323
 Value Chain Study and Market Assessment Farmer Managed Natural Regeneration (FMNR) Catalyst Project
REFNo: A607ES

The main objective of the value chain and market analysis was to identify complementary livelihood options or enterprises in FMNR project implementation areas that can be established in the demonstration and learning sites.
Uganda 2025-05-23 14:12:56 2028-05-23 Agricultural Sciences Non-Clinical Trial Non-degree Award
DARIUS OWACHI
ID: UNCST-2022-R009373
 Impact of Antimicrobial Stewardship Interventions on Healthcare Workers’ Antibiotic Prescription Patterns and Compliance with Standard Treatment Guidelines at Kiruddu Hospital; A Quality Improvement Study.
REFNo: HS5989ES

To assess the impact of antimicrobial stewardship interventions on the knowledge levels, antibiotic prescription patterns and compliance to standard treatment guidelines, by healthcare workers at Kiruddu National Referral hospital through quality improvement methods. ,
 Uganda 2025-05-23 14:10:37 2028-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Violet  Gwokyalya
ID: UNCST-2022-R010490
 Drivers of under-prescription of cervical cancer screening: evidence from Uganda
REFNo: HS5957ES

Main Objective
1. To quantify the drivers of under-prescription of cervical cancer screening among providers of routine care in Uganda
________________________________________
Specific Objectives
1. To evaluate whether providers lack knowledge of recommended cervical cancer screening practices
2. To identify patient characteristics that predict screening recommendation for cervical cancer.
3. To evaluate whether providers with appropriate knowledge of cervical cancer screening recommend screening to their clients (i.e., whether a know-do gap exists).

 Uganda 2025-05-23 14:05:07 2028-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sheila Balinda Nina
ID: UNCST-2021-R013804
 Analysing HIV-1 Reservoir Kinetics, and Host Immune Interactions among non-B subtypes.
REFNo: HS5936ES

General Objective

To understand the dynamics of HIV-1 reservoirs and host immune interactions among non-B subtypes infected participants in Uganda.

Specific objectives:
1. To compare the dimensions of the HIV-1 reservoir among Ugandans, including individuals with high viral loads at the start of ART, and those who have been on ART for varying durations.
2. To detect HIV-1 viral properties associated with latent reservoirs across HIV-subtypes, examining how these patterns may differ and contribute to disparities in reactivation tendencies in Uganda.
3. To detect immune correlates in relation to host characteristics, including HIV-1 specific, B-cells, innate immune cells, CD4 and CD8 cell lineage activation, and exhaustion markers.
4. To develop a supervised machine learning algorithm to predict the HIV-1 latent reservoir behaviours in Uganda.

 Uganda 2025-05-23 14:00:42 2028-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Betty Nalikka
ID: UNCST-2024-R016316
 Ecological and epidemiological dynamics of viruses in Ugandan bat populations.
REFNo: NS969ES

1. To determine the prevalence, diversity and genetic variation of viruses in different bat species, considering both time and space.
2. To use host density, distribution, and pathogen prevalence to develop models that can be used to forecast spillover risks from bats to other animals, including humans.
3. To investigate the duration of immunity to viruses in bats by sampling individuals across different age groups over time.

 Uganda 2025-05-23 13:58:46 2028-05-23 Natural Sciences Non-Clinical Trial Degree Award
Muge Cevik
ID: UNCST-2022-R011548
 Improving surveillance and detection of MPXV in Uganda
REFNo: SS3940ES

• To determine seroprevalence of MPXV among people living with HIV in Uganda • To elucidate the risk factors associated with infection.
 UK 2025-05-23 13:57:06 2028-05-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
ochuga patrick olanya
ID: UNCST-2024-R015276
 PREVALENCE, AND FACTORS ASSOCIATED WITH CHORIOAMNIONITIS AMONG WOMEN ADMITTED WITH PPROM AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS5949ES

To determine the prevalence and factors associated with chorioamnionitis among women admitted with PROM at MRRH
 Uganda 2025-05-23 13:54:31 2028-05-23 Medical and Health Sciences Non-Clinical Trial Degree Award
Nina Rugambwa Olivia
ID: UNCST-2019-R000213
 SAFEGUARDING MENTAL HEALTH OF CHILDREN WITH PHYSICAL DISABILITIES IN INCLUSIVE PUBLIC PRIMARY SCHOOLS: A CASE OF KAMULI DISTRICT, UGANDA
REFNo: SS3894ES

To explore the coping strategies of children with physical disabilities and their relationship to mental well-being in schools in Kamuli District.,3. To examine mental health safeguarding measures and their implementation in inclusive government primary schools in Kamuli District ,2. To document cultural beliefs and practices that promote mental health and inclusiveness of children with disability at school and in their communities in Kamuli District,1. To determine the mental health status of children with physical disabilities in government-inclusive primary schools in Kamuli district,This study seeks to create awareness about the mental health of children with disabilities and enhance their safety in inclusive government primary schools in Kamuli district.,
 Uganda 2025-05-23 13:43:10 2028-05-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Phiona Bukirwa
ID: UNCST-2022-R009880
 Colorectal Cancer Biology: Clinicopathologic characteristics, Mismatch Repair (MMR) status and prognostic factors of colorectal carcinoma in Sub-Saharan Africa
REFNo: HS5980ES

1. To determine the prevalence of Mismatch repair deficient (dMMR)/microsatellite instability-high (MSI-H) in FFPE tissue blocks of colorectal carcinoma in Sub-Saharan Africa.
2. To assess the association between histopathological parameters like tumor grading, tumor type, frequency of tumor infiltrating lymphocytes and tumor budding in microsatellite instability-high (MSI-H) FFPE tissue blocks of colorectal carcinoma in Sub-Saharan Africa.
3. To assess the association of clinical finding (age, sex, TNM stage, site of tumour) with mismatch repair status in FFPE tissue blocks of colorectal carcinoma in Sub-Saharan Africa.
4. To assess the prevalence of BRAF and KRAS mutation in FFPE tissue blocks of colorectal carcinoma in Sub-Saharan Africa.

 Uganda 2025-05-23 13:40:32 2028-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Godfrey Kubiriza Kawooya
ID: UNCST-2024-R003138
 Eco-innovative technologies for improved nutrition, sustainable production and marketing of Agro-ecological food products in Africa (INNOECOFOOD)
REFNo: A574ES

Main objective of the baseline study
The main objective of the baseline study is to scope community indigenous knowledge, gaps, attitudes and aquaculture practices in local lakes and rivers (living labs) on production, processing, marketing and consumption of aquaculture value chains (fish and selected Spirulina species) and insect species in Uganda.

Specific Objectives
i.To determine the current community Knowledge on sustainable production, processing and consumption of fish, spirulina and insects as food and feed.
ii.To determine the current community Attitude on sustainable production, processing and consumption of fish, spirulina and insects as food and feed.
iii.To determine the current community Practices on sustainable production, processing and consumption of fish, spirulina and insects as food and feed.
iv.Assess how socio-demographics factors influence the production, processing and consumption of fish, spirulina and insects as food and feed.

 Uganda 2025-05-23 13:39:33 2028-05-23 Agricultural Sciences Non-Clinical Trial Non-degree Award
ANNETTEE NAKIMULI OLIVIA
ID: UNCST-2022-R011194
 Genetic Associations of INfertility in Africa (The GAIN Study)
REFNo: HS5967ES

The GAIN study aims to identify genetic variants associated with unexplained primary infertility in African women
 Uganda 2025-05-23 13:37:00 2028-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rhoda Wanyenze
ID: UNCST-2021-R013352
 Uganda Population-based HIV Impact Assessment (UPHIA 2024-2025)
REFNo: HS5817ES

The primary objectives of UPHIA 2024-2025 are to:
1) Estimate the national and regional prevalence of HIV viral load suppression (VLS – defined as HIV RNA <1000 copies/milliliter(mL) in adults ages 15 years or older in the general population.
2) Estimate the prevalence of HIV at the national and regional level
3) Assess progress towards the UNAIDS 95- 95- 95 targets at the national and regional level

The secondary objectives of the survey are to:
1) Estimate the HIV incidence at the national level
2) Estimate the prevalence of HIV-related risk behaviors, knowledge, and attitudes
3) Establish the behavioural and demographic determinants of HIV prevalence and incidence
4) Determine the exposure to, uptake of and barriers to access to HIV-related services
5) Estimate the prevalence of elevated blood pressure, elevated blood glucose and obesity among the general population and people living with HIV
6) Assess the facilitators of and barriers to viral load suppression among people living with HIV on ART in two regions with the lowest VLS, based on the UPHIA 2020-21 survey findings.

 Uganda 2025-05-23 13:34:26 2028-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
DAVID KITYA
ID: UNCST-2022-R009620
 Analysis of the out-of-pocket costs of neurosurgical care in Uganda
REFNo: HS5875ES

3. To assess the socioeconomic impact of neurosurgical care on patients and their families/caregivers in Uganda, and to identify the key cost-related factors contributing to this burden within the local context.,2. To ascertain the proportion of patients experiencing catastrophic and impoverishing healthcare expenditure due to their neurosurgical care.,1. To determine the direct and indirect out-of-pocket costs borne by patients receiving neurosurgical care.,The main objective of this study is to quantify the OOP expenditure costs for patients receiving neurosurgical care in Uganda to estimate the proportion of patients experiencing CHE,
 Uganda 2025-05-23 13:30:41 2028-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
MARTHA GIMONO
ID: UNCST-2024-R016208
 The Readiness of Emerging Adults (18-25 years) Living with Type 1 Diabetes to Transition from Pediatric to Adult Healthcare in Jinja District - Uganda.
REFNo: HS5871ES

1. To develop transition screening tools for emerging adults living with T1D in Jinja District, Uganda.
2. To understand facilitators of transition readiness among emerging adults living with T1D in Jinja District, Uganda.
3. To determine the level of transition readiness among emerging adults living with T1D in Jinja District, Uganda

 Uganda 2025-05-23 13:28:29 2028-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Oculi Jasper
ID: UNCST-2024-R004987
 Azotobacter and Pseudomonas bio-fertilizer for enhanced yield of maize (Zea mays) and Turtle beans (Phaseolus Voulgaris) in Uganda
REFNo: A594ES

i. To isolate and characterize isolates of azotobacter and pseudomonas bio-fertilizers which is efficacious as bio-fertilizer in Uganda.
ii. To evaluate the efficacy of azotobacter and pseudomonas bio-fertilizers on growth and yield of maize (Zea mays) and turtle beans (phaseolus voulgaris) in the greenhouse trial at Kyambogo University.
iii. To evaluate the efficacy of azotobacter and pseudomonas bio-fertilizers on growth and yield of maize (Zea mays) and turtle beans (phaseolus voulgaris) in the field at Kyambogo University farm.

 Uganda 2025-05-23 13:24:17 2028-05-23 Agricultural Sciences Non-Clinical Trial Degree Award
Johnblack Kabukye Kabaalu
ID: UNCST-2019-R001109
 PEPROOM – Patient Engagement and Patient-Reported Outcomes in Oncology using Mobile health tools in Uganda: A mixed-methods formative study
REFNo: SS3900ES

Main Objective
1. This project aims to enhance patient engagement and empowerment by increasing cancer awareness through efficient and effective dissemination of cancer information and advice. It also aims to develop/adapt patient-reported outcomes (PROs) measures for patients with cancer in Uganda, and improve PROs through cancer awareness, PRO tracking, reminders and personalized support. Overall, the project will contribute to research and evidence on patient-centered care in Uganda.
Specific Objectives
1. to explore knowledge, attitudes, and practices of cancer care providers and patients at the Uganda Cancer Institute (UCI) with regards to patient empowerment and patient-reported outcomes (PROs
2. to identify PROs considered most important, relevant, and/or actionable for cancer care at the UCI, and develop/adapt measures (tools) to track these PROs
3. to develop, implement, and evaluate a telephone system for automated provision of cancer information related to the PROs and for administration of the PRO measures in (ii) above (i.e., in audio telephone questionnaire format)
4. to study the impact of the telephone system on the PROs above and other selected clinical care processes and outcomes (e.g., satisfaction with care, adherence to appointments, disease progression)
 Uganda 2025-05-23 13:23:23 2028-05-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Richard Idro
ID: UNCST-2021-R013599
 Development of a clinical decision support (CDS) tool to address the epilepsy treatment gap in Uganda: A pilot study
REFNo: HS5127ES

Aim 1: To develop a machine learning-enabled clinical decision support (CDS) tool to choose an appropriate anti-epileptic drug for initiating treatment among children with epilepsy. Aim 2: To evaluate the effect of the CDS tools on the treatment gap among children with epilepsy in nine health clinics around KCCA and Wakiso, where CDS tool will be implemented. Aim 3: To determine the adoptation and acceptability of the CDS tool among non-specialist providers, who diagnose and treat children with epilepsy (psychiatry clinical health officers and psychiatry nurse) in clinics around KCCA.
Uganda 2025-05-22 12:07:57 2028-05-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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