Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Noeline Nakasujja
ID: UNCST-2019-R001428
 Vitamin D and Gut Microbiota and Dementia rick in older adults with chronic HIV infection and demographically matched community controls. Adverse Synergy of Gut Dysbiosis and Vitamin D Deficiency in Alzheimer’s Disease and Related Dementia among Community Controls and Older Adults with Chronic HIV-infection
REFNo: HS6600ES

2) To interrogate the potential for heightened ADRD risk in sub-groups that differ according to co-prevalent chronic HIV infection, NCD (specifically high blood pressure), as well as genetic risk such as APOE e4. ,1) To investigate how changes in the composition and metabolic capacity of the gut microbiota contribute to dysregulations in the metabolome of VD and impact ADRD, through an enhanced inflammatory response (systemic, intestinal and CNS). ,
 Uganda 2025-10-17 19:32:06 2028-10-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Brenda Apeta
ID: UNCST-2025-R021698
 Historicising Gender Socialisation of Children In Lango Culture
REFNo: SS4515ES

I. To trace the evolution of gender roles, gender expectations, and social practices in Lango culture before the 19th century through to 2025.
II. To analyse how the evolution of children’s gender socialisation in Lango culture has influenced their gender identity.
III. To investigate the current perceptions of the Lango regarding traditional gender socialisation practices.
IV. To examine changes and continuity of gender-related cultural practices that foster or challenge gender equality among children.

Uganda 2025-10-17 19:28:23 2028-10-17 Social Science and Humanities Non-Clinical Trial Degree Award
Beatrice Kimono Washi
ID: UNCST-2025-R016727
 EXPLORING ADOLESCENT AUTONOMY IN HIV RESEARCH PARTICIPATION: PERCEPTIONS, BARRIERS, AND RECRUITMENT STRATEGIES IN KALUNGU DISTRICT.
REFNo: HS6504ES

Main Objectve:
To evaluate adolescents’ perceptions of autonomy in HIV research participation, identify the barriers that limit this autonomy, and assess research recruitment strategies used in Kalungu district.
specific objectives:
1. To assess adolescents’ perceptions of autonomy in making decisions about HIV research participation in Kalungu district.
2. To identify the barriers to adolescent autonomy during HIV research participation in Kalungu district.
3. To examine the strategies used to recruit adolescents into HIV research in Kalungu district.


 Uganda 2025-10-17 19:26:25 2028-10-17 Medical and Health Sciences Degree Award
Mercy Wanyana Mugonola
ID: UNCST-2023-R006482
 INNOVATIVE WORK BEHAVIOR AMONG ACADEMIC STAFF IN PUBLIC UNIVERSITIES IN UGANDA
REFNo: SS4389ES

Generally, the study seeks to explore strategies for enhancing innovative work behavior among academic staff in public universities. The study's major objective is to improve innovative work behaviors (IWB) by developing an IWB model that integrates the constructs of servant leadership, perceived organizational support, organizational culture, and employee empowerment from three different theories: social exchange, Denison's Organizational Culture Model, and Spritzer's empowerment theory. Specifically, eight objectives underpin this study namely: 1) to examine the relationship between servant leadership and IWB among academic staff of public universities, 2) to examine the correlation between perceived organization support and IWB of academic staff of public universities, 3) to assess the association between psychological empowerment and IWB among academic staff of public universities, 4) to examine the degree of association between servant leadership and psychological empowerment, 5) to determine the relationship between perceived organizational support and psychological empowerment among academic staff of public universities, 6) to examine the mediating influence of psychological empowerment in the relationship between servant leadership and IWB, 7) to examine the relationship between psychological empowerment and academic staff IWB and finally, 8) to assess how the relationship between perceived organizational support and IWB among staff of public universities is mediated by psychological empowerment.
Uganda 2025-10-17 19:24:25 2028-10-17 Social Science and Humanities Non-Clinical Trial Degree Award
LYDIACATRINA NAKIBWAMI
ID: UNCST-2024-R015974
 Perceptions And Experiences Of Married People Regarding Socioeconomic Status And Marital Happiness In Kawempe Division
REFNo: SS4328ES

I. To explore married people’s understanding of marital happiness
II. To examine the lived experiences of married people regarding socioeconomic status and marital happiness.
III. To discover the perceptions of married people regarding socioeconomic status and marital happiness.

 Uganda 2025-10-17 19:22:52 2028-10-17 Social Science and Humanities Non-Clinical Trial Degree Award
Anthony  Batte
ID: UNCST-2022-R011127
 Assessing Worldwide Acute Kidney Injury Epidemiology in Neonates( AWAKEN) 2.0 Study
REFNo: HS6568ES

Determine if AKI can predict chronic kidney disease, recurrent AKI and hypertension during early childhood,Determine if AKI is independently associated with mortality, length of stay, and discharge serum creatinine (SCr). ,Describe prevalence of AKI in a multi-national multi-center retrospective cohort, 5 years after the original AWAKEN study,
 Uganda 2025-10-17 19:20:52 2028-10-17 Medical and Health Sciences Non-degree Award
Martin Mutambuka
ID: UNCST-2025-R020119
 A comparative assessment of workload and resource utilization among Ugandan women associated with cooking of selected commercial beans
REFNo: A645ES

(1) To determine the Cooking Times of selected popular, commercial bean varieties (both Biofortified and non Biofortified) under a controlled laboratory environment. (2) To determine the Cooking Times and Costs of Resources used for selected commercial bean varieties under Household Field Kitchen environments (using firewood, charcoal and briquettes). (3) To determine how time saved from various activities translates into women’s ability to undertake additional productive ventures. (4) To determine Consumer Acceptability of selected Biofortified bean varieties by Rural and Urban consumers.
 Uganda 2025-10-17 19:10:57 2028-10-17 Agricultural Sciences Non-Clinical Trial Non-degree Award
Dreck Ayebare
ID: UNCST-2025-R019088
 Delivery and use of poultry vaccines in Uganda: A systems mapping and field-level study
REFNo: A655ES

Overall Aim To map and analyse the poultry vaccine supply system in Uganda, examining both upstream supply chain structures and downstream use behaviours, in order to identify institutional, logistical, and behavioural barriers to effective, equitable, and sustainable vaccine-based disease prevention. Specific Objectives Part A: Systems mapping 1. To map the structural and logistical flow of poultry vaccines in Uganda, from importation through distribution to the point of administration. 2. To examine institutional roles, interdependencies, and governance arrangements that influence vaccine regulation, quality control, and coordination. 3. To assess inequities in vaccine availability, cold chain access, pricing, and service delivery across geographic regions, institutional levels, and actor groups. 4. To co-develop stakeholder-informed recommendations for improving supply chain efficiency, regulatory coordination, and equitable vaccine access. Part B: Field-level practices 1. To identify the most used poultry vaccines and their sourcing patterns at the farm level. 2. To evaluate compliance with recommended vaccine handling and administration practices among farmers, veterinary workers, and agro vets. 3. To explore behavioural drivers—including knowledge, perceptions, motivations, and decision-making—that influence vaccine uptake and misuse. 4. To assess the role of agro-vet shop interactions, veterinary advice, packaging/labelling, and social norms in shaping field-level behaviours. To quantify key knowledge gaps, operational challenges, and access barriers that limit effective poultry vaccine use at the farm level.
Uganda 2025-10-17 19:09:27 2028-10-17 Agricultural Sciences Non-Clinical Trial Degree Award
Lydia Mwikali
ID: UNCST-2021-R012798
 PERFLUOROALKYL SUBSTANCES IN SOURCE AND TREATED DRINKING WATER, AND THEIR REMOVAL USING CORNCOB-DERIVED BIOCHAR
REFNo: NS1042ES

vi. To elucidate the adsorption mechanisms of PFAS removal by corncob-derived biochar and MOFs, v. To determine the adsorption capabilities of the corncob biochar and MOFs for PFAS removal,iv. To prepare, synthesize and characterize corncob-derived biochar and MOFs for PFAS removal,iii. To estimate exposure and human health risk assessment of PFNA, PFHxS, PFOS and PFOA,ii. To determine spatial distribution of PFAS in water sources.,i. To determine the concentration of PFAS in source and treated drinking water,To determine the occurrence and human health risk assessment of PFAS in source and treated drinking water and evaluate the efficacy of corncob-derived biochar, and metal organic frameworks (MOFs) in PFAS removal.,
 Kenya 2025-10-17 19:08:34 2028-10-17 Natural Sciences Non-Clinical Trial Degree Award
Judith Owokuhaisa
ID: UNCST-2022-R011528
 ISOLATION AND CHARACTERIZATION OF BACTERIOPHAGES FROM WASTE WATER WITH BACTERICIDAL EFFECT ON ANTIBIOTIC RESISTANT ESKAPEE PATHOGENS IN SOUTH WESTERN UGANDA
REFNo: HS6636ES

1.) To determine the phenotypic and genotypic characteristics of bacteriophages isolated from surface and waste water in south western Uganda.
2.) To identify antibiotic resistance genes in bacteriophages and antibiotic resistant ESKAPEE pathogens.
3.) To assess the effect of isolated bacteriophages on antibiotic resistant ESKAPEE isolates.


Uganda 2025-10-17 19:07:48 2028-10-17 Medical and Health Sciences Non-Clinical Trial Degree Award
Ombeva  Malande Oliver
ID: UNCST-2024-R004335
 Determinants and Strategies for Childhood Immunization among Populations Facing Rural and Low-Income Vulnerabilities in Uganda
REFNo: HS6548ES

1.To identify the barriers to and facilitators of childhood routine immunization programs among populations facing low-income urban and rural vulnerabilities in Uganda; 2.To determine how the most significant facilitators and barriers to vaccination perceived by knowledge holders could be enhanced and mitigated, respectively; 3.To understand current vaccination strategies used to address barriers and to enhance facilitators for childhood vaccination programs; and 4.To highlight opportunities for enhancing current implementation strategies and map out priority areas based on knowledge holders’ perspectives.
Kenya 2025-10-17 19:06:55 2028-10-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nixon Niyonzima
ID: UNCST-2020-R014577
 HPV subtypes and pap smear findings among women screened for cervical cancer at Uganda Cancer Institute (UCI), Uganda
REFNo: HS3830ES

To determine the association between demographic characteristics, HPV positivity, and Pap smear findings among women seeking cervical cancer screening services in Uganda,4) To describe the findings from Pap smear among women seeking cervical cancer screening in Uganda,3) To determine the prevalence of HPV positivity among women living with HIV, seeking cervical cancer screening in Uganda,2) To determine the prevalence of HPV subtypes among women seeking cervical cancer screening in Uganda.,1) To describe the demographic characteristics of women seeking cervical cancer screening in Uganda,To determine the prevalence of HPV subtypes, and the association with demographic characteristics and Pap smear findings among women attending cervical cancer screening in Uganda.,
 Uganda 2025-10-17 19:05:45 2028-10-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
MBABAZI GRACEMARY
ID: UNCST-2025-R017863
 DYNAMIC CAPABILITIES AND FINANCIAL PERFORMANACE OF MICROFINANCE INSTITUTIONS IN UGANDA
REFNo: SS4124ES

1) To find out the relationship between dynamic capabilities and the financial performance of Tier 4 MFIs in Uganda.

2) To find out the relationship between dynamic capabilities and innovation among Tier 4 MFIs in Uganda

3) To establish the relationship between innovation and the financial performance of Tier 4 MFIs in Uganda.

4) To examine the mediating effect of innovation in the relationship between dynamic capabilities and the financial performance of Tier 4 MFIs in Uganda.

 Uganda 2025-10-17 19:04:48 2028-10-17 Social Science and Humanities Non-Clinical Trial Degree Award
JOHNBOSCO NDINAWE
ID: UNCST-2025-R018067
 QUALITY OF LIFE AND USE OF mHEALTH AMONG CANCER PATIENTS RECEIVING PALLIATIVE CARE IN WESTERN UGANDA
REFNo: HS6248ES

1.4 Research objectives: 1.4.1 Main Objective: To examine the quality of life (QOL), associated factors, and use of mHealth interventions among cancer patients receiving palliative care in Western Uganda. 1.4.2 Specific Objectives: 1) To examine the nature and use of mHealth interventions for PC for cancer patients in SSA based on the available literature. 2) To determine the level of QOL and associated factors among cancer patients under PC in Western Uganda. 3) To establish the effect of a text message-based intervention on the QOL of cancer patients receiving PC in Western Uganda.
Uganda 2025-10-17 19:03:25 2028-10-17 Medical and Health Sciences Non-Clinical Trial Degree Award
Godfrey Zari Rukundo Zari
ID: UNCST-2019-R001500
 WHO LIVE LIFE guide with DHMT as Champions for Suicide Prevention across the lifespan in rural Uganda (WLLDC-SP)
REFNo: HS4371ES

To build an ecosystem for community engagement and training in suicide prevention in rural Uganda.,To evaluate the feasibility of an implementation strategy consisting of WHO LIVE LIFE guide with DHMT as Champions for Suicide Prevention across the lifespan in rural Uganda,To co-design an implementation strategy manual for the WHO LIVE LIFE guide with the District Health Management Team as Champions for suicide prevention across the lifespan in rural Uganda. ,To co-design and evaluate the feasibility of a contextually tailored implementation strategy to identify and prepare members of the District Health Management Team (DHMT) as champions: the “WHO LIVE LIFE guide with DHMT as Champions for Suicide Prevention across the lifespan in rural Uganda,
 Uganda 2025-10-17 18:59:00 2028-10-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Christopher Ketola Tobias
ID: UNCST-2022-R009343
 Establishing baselines in fauna diversity, phenology and abundance in key biodiversity hotspots across Uganda through collaborative research and capacity building
REFNo: NS889ES

Our project will sample birds and bats targeting biodiversity hotspots adjacent to and within
protected areas in Uganda. Through multiple visits across the next six years we plan to sample in
distinct biomes such as the North (Moroto, Kidepo valley, Agoro-agu, Morungole, Achwa)
Northeast (Pian Upe, Nakapiprit, Matheniko-Bokora), East (Mount Elgon, Loporokocho, Bukwo),
Northwest (Otzi forest, Ajai wildlife reserve, Luuku forest) southwest (Mgahinga, Bwindi and
around lake Victoria (Buvuma Island, Kalangala, Bugala). These regions are known to support
unique and often locally endemic species. In addition, many of these areas, such as the Kidepo and
the overall Karamoja regions, are notably understudied compared to regions in Western Uganda
 Canada 2025-10-17 18:56:23 2028-10-17 Natural Sciences Non-Clinical Trial Non-degree Award
Hakim  Kalungi
ID: UNCST-2025-R018251
 Process evaluation of the She Cares Program model in Uganda.
REFNo: HS6251ES

Study objective 1: Analyze change in FP services among adolescent girls and young women during the She Cares project period.
Study Objective 2: Examine how the She Cares outreach model and solutions were used by
adolescent clients and how clients experienced care with self-care promoters
Study Objective 3: Examine how the She Cares program model was implemented, its feasibility,
acceptability and potential scalability
Study Objective 4: Analyze the cost efficiency of the She Cares program model
 Uganda 2025-10-17 18:50:38 2028-10-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Stephen Balinandi Karabyo
ID: UNCST-2023-R007529
 Evaluation of OraSure’s OraQuick Ebola Rapid Antigen Test using Sudan Ebolavirus in Preparation for Cadaveric Surveillance
REFNo: HS6258ES

1. To evaluate the performance characteristics (sensitivity, specificity, positive predictive value and negative predictive value of the OraQuick RDT for Sudan Virus detection using archived cadaveric oral swabs.
2. To determine the reliability of the OraQuick RDT in identifying true Sudan virus cases in a controlled laboratory setting before field implementation
 Uganda 2025-10-17 18:48:41 2028-10-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ASIIMWE EMILY
ID: UNCST-2025-R020015
 THE ROLE OF MATERNAL EMPLOYMENT IN THE TEACHING AND LEARNING OF YOUNG LEARNERS IN EARLY CHILDHOOD EDUCATION CENTRES IN NANSANA MUNICIPALITY ,WAKISO DISTRICT, UGANDA
REFNo: SS4140ES

1.TO IDENTIFY THE IMPACT OF IMPACT OF MOTHERS' EMPLOYMENT ON CHILDREN'S ACADEMIC PERFORMANCE
2.TO FIND OUT STRATEGIES USED BY FAMILIES IN DEVELOPING THE ACADEMIC POTENTIALS OF THEIR CHILDREN
3.TO ANALYSE CHALLENGES FACED BY WORKING MOTHERS IN BALANCING THEIR DUTIES WITH CHILD CARE
 Uganda 2025-10-17 18:46:52 2028-10-17 Social Science and Humanities Non-Clinical Trial Degree Award
Jacklyn Arinaitwe Makaaru
ID: UNCST-2024-R015354
 LABE HOME-BASED EARLY CHILDHOOD EDUCATION EVALUATION PROJECT
REFNo: SS4168ES

a) What are the components and assumptions of the home based ECD model that make it work?
b) Does the model have correlational/cause outcomes on the community and children in terms of learning outcomes and retention in school?
c) How can LABE scale up with several adopters while maintaining the integrity of the model?

 Uganda 2025-10-17 18:42:47 2028-10-17 Social Science and Humanities Non-Clinical Trial Non-degree Award
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