Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Alex Ario Riolexus
ID:
Surveillance System Performance, Timeliness Metrics and Framework of Response to Anthrax Outbreaks in Uganda: Implications for Programming and Control of Zoonotic Diseases Epidemics
REFNo: HS4277ES

4- Develop a One Health Model response framework for zoonotic disease outbreaks,3- Examine timeliness of response to anthrax outbreaks in Uganda for the period 2014 to 2023 and compare with 7:1:7 as a metric for strengthening response and improving systems in real time,2- Assess the human and animal anthrax surveillance system functions and attributes in Uganda,1- Identify gaps in epidemiological investigations of anthrax outbreaks in Africa for the period 2014 to 2023,The general objective of this study is to assess performance of the surveillance system and timeliness of response to anthrax outbreaks in Uganda, 2014 - 2023.,
Uganda 2024-07-22 17:13:33 2027-07-22 Medical and Health Sciences Non-Clinical Trial Degree Award
Swaibu Zziwa
ID: UNCST-2022-R011017
MOBILITY RECOVERY AFTER A LOWER LIMB BONE FRACTURE; EFFECTS OF A MULTI- COMPONENT HOME BASED REHABILITATION PROGRAM ON MOBILITY RECOVERY IN GREATER KAMPALA, UGANDA
REFNo: HS4641ES

1.To describe the type of care received by patients with lower limb fractures after hospital discharge in Greater Kampala, Uganda. 2.To determine mobility recovery and predictors of mobility recovery among patients with lower limb bone fractures in Greater Kampala, Uganda. 3.To develop and validate a multi component home based rehabilitation program to improve mobility recovery among patients with lower limb bone fractures in Greater Kampala, Uganda. 4.To evaluate the effect of a multi component home based rehabilitation program on mobility recovery among patients with lower limb bone fractures in Greater Kampala, Uganda.
Uganda 2024-07-22 17:09:51 2027-07-22 Medical and Health Sciences Non-Clinical Trial Degree Award
AKANKWASA JOHNSON
ID: UNCST-2023-R006429
Factors Associated with Home Based Care Services in the Control of Covid - 19 Infection in Sheema Municipality, Sheema District
REFNo: SS2402ES

3.To establish the existing, new policies and practices about home based care agencies that addressed challenges resulting from the COVID-19 pandemic in the 3 years of the peak pandemic.,2. To establish the social demographic, social economic and environmental factors that affected home based care services (HBC) in all the COVID-19 suspects during 2019 pandemic.,1. To investigate the level of utilization of Home Based Care services (HBC) in percentages among the isolated COVID-19 suspects in the control of COVID-19 infection in Sheema Municipality from 2020 to 2023.,To establish factors associated with Home Based Care Services (HBC) during COVID -19 infection in Sheema Municipality, Sheema District.,
Uganda 2024-07-22 17:06:47 2027-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
Mathias Seviiri
ID:
Genetics of Glaucoma in High-risk Diverse Populations (GoGLAD) Study
REFNo: HS3427ES

General objective
To apply and critically evaluate the efficacy of genetic-based risk prediction models for glaucoma in an understudied, high-risk, genetically diverse continental African population in Uganda.

Specific objectives
1. To test the feasibility of collecting quality pilot clinical data on glaucoma related phenotypes, genetic data from a unique high-risk diverse population in Uganda.
2. To assess cross-ancestry genetic-based prediction of glaucoma risk in major diverse ancestry populations.
2A- To apply our current European-based genetic prediction model of glaucoma to a high-risk population of African ancestry from Uganda.
2B - To develop, and calibrate an African ancestry genetic prediction model of glaucoma and implement it in populations of European and African ancestries.
2C- To develop, model and calibrate a cross-ancestry genetic prediction model and apply it in populations of European and African ancestries.
3. To apply artificial intelligence to eye images to characterise ancestral differences in glaucoma risk and evaluate estimation of disease risk and progression.
4. To assess participants’ attitude towards genetic testing for glaucoma.

Uganda 2024-07-22 17:03:10 2027-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nura Izath
ID: UNCST-2022-R009201
Autothermo-a wearable continuous temperature measuring bracelet with a central display screen.
REFNo: HS3034ES

To assess the performance of Autothermo- a wearable continuous temperature measuring bracelet and a central display screen in comparison to the standard thermometer.,To assess the feasibility and acceptability of Autothermo among health workers and parents/caregivers of admitted neonates at Mbarara Regional Referral Hospital(MRRH).,
Uganda 2024-07-22 16:57:35 2027-07-22 Medical and Health Sciences Clinical Trial Non-degree Award
David Aderu
ID: UNCST-2023-R008280
Mainz II Pouch: A viable option for the incurable fistula in Uganda
REFNo: HS3247ES

3. To assess the quality of life of recipients of the Mainz II pouch in clients with fistula deemed incurable at SRRH from 2009 to 2018.,2. To describe sonographic characteristics of the upper urinary tract in recipients of the Mainz II pouch procedure at SRRH from 2009 to 2018.,1. To determine the biochemical profile of patients with fistula deemed incurable who have undergone Mainz II pouch procedure at SRRH from 2009 to 2018.,To evaluate the viability of the Mainz II urinary diversion for women with Fistula deemed incurable in Uganda. ,
Uganda 2024-07-22 16:53:11 2027-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Aisha Nanyiti
ID: UNCST-2021-R013489
Electric cooking in the energy transition: how much subsidization is needed?
REFNo: SS2896ES

To assess the willingness to pay for modern electronic cooking technology within the grid connected urban and peri-urban areas. To assess the effect of benchmark goods on the willingness to pay for modern electronic cooking technology. To assess the impact of information provision towards the demand for modern electronic cooking technology within the grid connected urban and peri-urban areas.
Uganda 2024-07-22 16:52:07 2027-07-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
JOSELYN RWEBEMBERA
ID: UNCST-2021-R013915
Identifying the Essential Elements of Case Managers and Peer Support Groups for Prophylaxis Adherence in Rheumatic Heart Disease” (CAMPS Plus)
REFNo: HS4346ES

Objective 1: Determine the difference in 1-year SAP adherence rates of children newly diagnosed with RHD in Uganda receiving one of two support strategies: case manager only (CM) and case manager plus peer support group (CM + PG).

Objective 2: Explore implementation determinants among case managers, participants, and participant families to inform deployment of program at scale.
Uganda 2024-07-22 16:49:34 2027-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ronald Kiguba
ID: UNCST-2019-R000844
Understanding adverse drug reactions to dolutegravir and isoniazid in people living with HIV in Uganda: incidence, risk factors, management and patient reporting
REFNo: HS3364ES

To determine the incidence, characteristics and risk factors of ADRs to DTG/ IPT in PLHIV in Uganda,To identify barriers and facilitators of using the app to report ADRs by PLHIV in Uganda,To determine the rate of ADR-reporting by PLHIV at selected ART-sites in Uganda,To implement the Med Safety app to promote ADR-reporting by PLHIV in Uganda,To identify genetic polymorphisms associated with DTG-induced weight gain and hyperglycaemia, and isoniazid-related hepatotoxicity, using the GWAS approach among PLHIV in Uganda,To investigate the prevention, monitoring, management of ADRs to DTG/ IPT in PLHIV in Uganda,
Uganda 2024-07-22 16:37:17 2027-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Elisa  Macchi
ID: UNCST-2023-R004097
Pressure to Hire, Technology Adoption, and Productivity: Experimental Evidence from Uganda
REFNo: SS2013ES

1. The project aims at contributing to several strands of the literature. First, an emerging literature
hasshown how social- and self-image concerns affect the labor market through changesin the labor
supply

2. Our evidence suggests that the reputational concerns associated to hiring and technology
adoption decisions are induced by resource-sharing practices with kin and neighbors.

3. Finally, our work links to the literature on cross-country differences in productivity. Lewis et al.
(1954) observed that developing economies have a large “traditional sector” where marginal
productivity is low and where workers may be compensated above their marginal product through
informal arrangements (see Gollin (2014) for a recent discussion). When wages do not equal
marginal product, workers may be employed in relatively less-productive tasks, resulting in
misallocations. Gollinetal
Italy 2024-07-22 16:32:03 2027-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
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