Ayomide Atoki Victor
ID: UNCST-2022-R008808
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BIOMEDICAL EVALUATION OF HESPERIDIN AND NARINGENIN ON NEUROLOGICAL INDICES IN DROSOPHILA MELANOGASTER MODEL OF ALZHEIMER’S DISEASE
REFNo: HS3813ES
Assess the expression of genes relevant to neuronal function in flavonoid-treated flies,Evaluate quantitatively the level of amyloid precursor protein in the flies,Determine the influence of Hesperidin and Naringenin on in vivo antioxidant status in the flies,Assess the effect of Hesperidin and Naringenin on activities of critical enzymes relevant to Alzheimer’s disease in the flies ,Evaluate the effect of Hesperidin and Naringenin on geotaxis, memory and life span in both wild (Harwich strain) and transgenic (Bloomington stock P{UAS-APP695-N-MYC}, P{UAS:BACE1}) Drosophila melanogaster,The main objective of the study is to assess the effect of Hesperidin and Naringenin on biomarkers of neurodegeneration in transgenic D. melanogaster model of Alzheimer’s disease.,
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Nigeria |
2025-02-14 15:22:49 |
2028-02-14 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
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Joseph Matovu KB
ID: UNCST-2020-R014654
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Reducing hazardous alcohol use and optimizing treatment as prevention among men living with HIV in risk environments
REFNo: HS5558ES
Understand barriers and facilitators in the inner and outer context for implementing the components of Kisoboka within the routine clinical setting to inform future widespread implementation guided by the Exploration, Preparation, Implementation and Sustainment (EPIS) framework and documentation of intervention and implementation costs. ,Assess the impact of the Kisoboka intervention and its components on measures of psychological, physical, and socioeconomic well-being that capture frequent comorbidities of people living with HIV and are associated with achieving successful treatment as prevention,Determine the efficacy of the Kisoboka intervention and its components on alcohol and HIV outcomes among hazardously drinking men living with HIV in Uganda in a 2x2 factorial RCT. ,Assess the efficacy of Kisoboka and its components (BE & MI) to gain insight into Kisoboka’s potential effect, determine if BE and MI interact and examine barriers and facilitators for implementing Kisoboka within routine clinical settings to inform future widespread implementation.,
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Uganda |
2025-02-14 15:19:41 |
2028-02-14 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
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Bruce Kirenga J
ID: UNCST-2019-R001460
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A Prospective, Clinical Trial Examining the Immune Response of Participants Receiving Modified Vaccinia Ankara (MVA) Vaccine in Africa,”-Mpox Vax Africa
REFNo: HS5575ES
To determine:
the development of MVA-BN-specific antibodies at week 6 post-first vaccination with MVA-BN in
a population recruited in Africa, and compare to a population recruited in Europe.
Durability of MVA-BN-specific antibodies at week 24 post-first vaccination with MVA-BN.
? Factors associated with MVA-BN-specific antibody responses at week 48 post-first
vaccination with MVA-BN.
? Durability of MVA-BN-specific antibodies at week 48 post-first vaccination between a
population recruited in Africa and a population recruited in Europe.
? Durability of MVA-BN-specific antibodies at week 48 post-first vaccination with MVA-BN in
understudied populations (women and PLWH).
? Prevalence of asymptomatic seroconversion to mpox by week 48 post-first vaccination
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Uganda |
2025-02-08 13:35:10 |
2028-02-08 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Bruce Kirenga J
ID: UNCST-2019-R001460
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THE SECOND UGANDA TB PREVALENCE SURVEY (TBPS2)
REFNo: HS5269ES
Estimating the sizes of key and vulnerable TB populations as defined in the national gender and key and vulnerable populations assessment report nationally and sub nationally,Evaluating factors associated with TB including HIV, diabetes, undernutrition, tobacco smoking, alcohol ab use, and socio-economic status,,Updating population-based estimates of TB burden using results from the prevalence survey ,Assessing healthcare-seeking behaviors and understand where individuals with TB symptoms seek medical care,The secondary objectives of TBPS2 in Uganda encompass: The prevalence of symptoms suggestive of pulmonary tuberculosis (PTB) and determining radiological abnormalities among individuals aged ?15 years, ,The primary objective is to determine the national and subnational prevalence of bacteriologically confirmed pulmonary TB among the general population aged ?15 years,The goal of the survey is to enable the country (MOH/NTLP and partners) to gain a better understanding of the current burden of TB, health-seeking behavior and health system response in order to identify ways of improving TB programming towards ending TB in the country.,
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Uganda |
2025-02-07 18:27:07 |
2028-02-07 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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DANIEL KIIZA
ID: UNCST-2024-R004044
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Retrospective chart review of patients with Laboratory-Confirmed Sudan Virus Disease Hospitalized in Two Ebola Disease Treatment Units in Uganda (September 2022 to January 2023)
REFNo: HS5541ES
To evaluate the safety and clinical course of patients receiving investigational treatments for SVD,To identify host and disease factors associated with outcomes from SVD,To characterize the natural history and outcomes of Sudan virus disease (SVD) among hospitalized patients with RT-PCR detected Orthoebolavirus sudanense (SUDV) RNA,
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Uganda |
2025-02-07 18:10:59 |
2028-02-07 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Clare Bangirana Ahabwe
ID: UNCST-2021-R012842
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AN OUTCOME RESEARCH ON THE WESTERN UGANDA BANTWANA PROGRAM ON VIOLENCE AGAINST CHILDREN IN SCHOOLS AND SURROUNDING COMMUNITIES (VACiSC) IN THE THREE DISTRICTS OF KABAROLE, KYENJOJO and BUNYANGABU
REFNo: SS3625ES
The study aims to assess the effectiveness of the Western Uganda Bantwana Program (WUBP) in preventing and responding to Violence Against Children (VAC), including child sexual abuse (CSA), in schools and surrounding communities in the three Districts of Kabarole, Kyenjojo, and Bunyangabu
Specific Objectives
1. To measure the change in knowledge, attitude and practices on risks exposures to VACiSC including CSA with focus on prevention and response among children, young adults, caregivers and teachers.
2. To assess how the WUBP aligned to the needs of communities and existing practices (structures and approaches) on prevention and response to VACiSC including CSA.
3. To evaluate the role of caregivers, teachers, para-social workers, and community leaders in creating and maintaining safe environments for children.
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Uganda |
2025-02-07 18:09:14 |
2028-02-07 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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Eva Smallegange Sophia
ID: UNCST-2023-R005788
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Effectiveness of PlayMatters in Uganda: a teacher professional
development programme aiming to integrate Learning through Play as
pedagogical approach in the classroom
REFNo: SS3617ES
1. To study the effectiveness of PlayMatters Teacher professional Development program on teacher practices and teacher wellbeing.
2. To study how do the effects of the intervention vary by teachers’ age, gender, displacement status, level of education and professional experience?
3. To study how do effects of the intervention vary by differences in adherence to implementation of the Teacher Continuous Professional Development (TCPD) component of the intervention?
4. To study the effectiveness of the PlayMatters Teacher professional Development program at child outcome level (cognitive, social, emotional, physical and creative skills and on their mental health and wellbeing).
5.To study the cost-effectiveness of the PlayMatters intervention.
|
Netherlands |
2025-02-07 18:07:38 |
2028-02-07 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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Damari Atusasiire
ID: UNCST-2024-R002645
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Evaluation of the One Acre Fund project - making 34,000 coffee farmers more resilient by 2027
REFNo: A560ES
To establish whether all household members are equally benefiting from the impacts of the project and how? ,To determine which pursued pathways of change are the main drivers in delivering outcome and impact? ,To establish the causal effects of the project for direct project participants? ,
|
Uganda |
2025-02-07 18:04:15 |
2028-02-07 |
Agricultural Sciences |
Non-Clinical Trial |
Non-degree Award |
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Michelle Brown
ID: UNCST-2022-R009670
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Describing the vocal repertoire of L’Hoest’s monkeys
REFNo: NS410ES
To test whether L’Hoest’s monkeys (Allochrocebus lhoesti) contradict the ‘social complexity hypothesis’ by determining whether they communicate in frequencies too low for human hearing.
|
USA |
2025-02-07 18:02:59 |
2028-02-07 |
Natural Sciences |
Non-Clinical Trial |
Non-degree Award |
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Damari Atusasiire
ID: UNCST-2024-R002645
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Incidence and economic impacts of bovine mastitis in smallholder dairy farms in Kenya and Uganda
REFNo: A564ES
To assess knowledge of bovine mastitis, its control and treatment among smallholder dairy farmers.
To assess the effectiveness of using cell phone technology as a method of disseminating information on udder health to farmers.
To estimate the incidence rate of clinical and subclinical mastitis among recently-calved dairy cows (?4 weeks prior to baseline data collection).
To determine the drivers of bovine mastitis among sampled dairy cows.
To estimate the monthly and annual financial losses attributed to clinical and subclinical mastitis.
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Uganda |
2025-02-07 18:01:56 |
2028-02-07 |
Agricultural Sciences |
Non-Clinical Trial |
Non-degree Award |
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