Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Charles Masembe Kikubo
ID: UNCST-2019-R001092
Investigating the dynamics and clinical outcome of African swine fever infection at pig farms in an endemic livestock wildlife setting in Uganda
REFNo: A355ES

1) Assess the spatial distribution of pig farmers in the study areas and recruit them
2) Determine the ASF virus molecular characteristics in apparently healthy domestic pigs
3) Determine the genetic characteristics and relationships of ASFV isolated from domestic pigs
4) Determine the full genome characteristics of the unique lineages obtained from domestic pigs
5) To establish an ASF biobank of clinical materials that are curated with clinical outcomes
6) Establish Ugandan Genotype IX repository at PIADC - for genomics and vaccine research
7) Build rapid ASF whole genome sequencing capacity in endemic settings

Uganda 2024-08-01 16:54:11 2027-08-01 Agricultural Sciences Non-Clinical Trial Non-degree Award
David Kibirige
ID:
DESIGN AND IMPLEMENTATION OF A PV SYSTEM FOR EMERGENCY SITUATION IN HEALTH FACILITIES IN RWEBISENGO UGANDA
REFNo: SIR363ES

4. To carryout hardware design and field test of the PV system,3. To design an improved inverter system for both AC single phase and three phase for PV application.,2. To model a PV power system circuit using Proteus software as well as carrying out its dynamic modeling using Simulink,1. To carry out Electrical and thermal analysis of a PV system to be used during the study,The aim of this research is to design a PV system that can be utilized during emergency situation in health facilities in Rwebisengo Uganda.,
Uganda 2024-08-01 16:05:23 2027-08-01 Engineering and Technology Non-Clinical Trial Degree Award
EDWINAH ATUSINGWIZE
ID: UNCST-2023-R007893
Exploring Stakeholder perspectives of the social determinants of malaria in Uganda
REFNo: HS4271ES

3. To explore barriers and facilitators to addressing the social determinants of malaria.,2. To examine how the social determinants of malaria are addressed in policy making and practice. ,1. To explore stakeholder perspectives of the social determinants of malaria.,The overall aim of this study is to explore stakeholder perspectives and experiences of the social determinants of malaria in Uganda in order to inform malaria prevention policy and practice. ,
Uganda 2024-07-26 16:04:20 2027-07-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Alen Musisi
ID: UNCST-2022-R009338
Knowledge, Attitude, and Practice on Radiation Protection Among Radiation Safety Officers in Uganda.
REFNo: HS4617ES

To determine the radiation protection knowledge level among RSOs
To determine the level of attitudes of RSOs towards radiation protection and safety
To determine radiation protection practices among RSOs

Uganda 2024-07-26 16:03:08 2027-07-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jean Damascene Niyonsenga
ID:
Role of PT in Ugandan Neurosurgical Transitional Care
REFNo: HS4400ES

This study aims to determine acceptability and feasibility of utilizing an interdisciplinary discharge planning protocol to improve team communication and increase patient referral to outpatient rehabilitation services in two public Ugandan hospitals.
Rwanda 2024-07-26 16:01:48 2027-07-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mbisi Muhindo Enosh
ID:
HOST COMMUNITIES’ RELATIONS AND REFUGEE ADAPTABILITY AT KYAKA II AND KYANGWALI SETTLEMENTS IN WESTERN UGANDA
REFNo: SS2953ES

To examine the role of social cohesion within host communities in facilitating refugee adaptability at Kyaka II and Kyangwali settlements,To investigate how Attitudes and Perceptions of host communities influence Refugee Adaptability at Kyaka II and Kyangwali settlements,To assess the socio-economic and political factors contributing to refugee adaptability at Kyaka II and Kyangwali settlements,To examine the impact of legal and policy framework on Refugee Adaptability within Host communities at Kyaka II and Kyangwali settlements in Uganda,To examine the dynamics and factors influencing the relationship between host communities and refugees, and to understand the impact of this relationship on the adaptability and integration of refugees at Kyaka II and Kyangwali settlements,
Uganda 2024-07-26 15:59:56 2027-07-26 Social Science and Humanities Non-Clinical Trial Degree Award
Doris Kwesiga
ID:
Implementer’s Voices: An input to the Lancet Commission on Evidence-based Implementation in Global Health
REFNo: HS4408ES

To examine the insights and experiences of LMIC health sector implementers on the use of evidence in their work, so as to identify barriers and enablers and design interventions to increase evidence-based implementation.,ii. What are the gaps between evidence and implementation, and how can these be closed?,i. How and why, do (or don’t) implementers use evidence? ,
Uganda 2024-07-26 15:58:42 2027-07-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ismail  Draguma Legason
ID: UNCST-2021-R012130
Molecular profiling of Epstein-Barr virus genome and expression in endemic Burkitt Lymphoma (EBVL study)
REFNo: HS4198ES

1. The main goal of the study is to examine the molecular architecture of EBV, its expression pattern, and the determinants of viral pathogenesis in endemic Burkitt lymphoma. ,Perform differential gene expression and protein analysis on formalin fixed-paraffin embedded BL tissues using RT- PCR or NanoString and analyse the data for: i) differentially expressed genes and proteins ii) gene and protein expression levels iii) correlation with tumour stage and viral strains ,Perform whole genome sequencing of EBV from clinical samples (ctDNA for eBL and plasma for healthy controls) and analyse data for: i) viral strains and co-infection ii) Mutations (SNVs, Indels, and structural variants) and compare frequencies iii) mutational signatures iv) viral population structure -phylogenetics and decomposition matrices to infer evolutionary relatedness with publicly available strains. ,
Uganda 2024-07-26 15:56:08 2027-07-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Sarah  Mayanja
ID:
Effect of the Triple S technology on farmers' food security in northern and eastern Uganda
REFNo: A438ES

3. To compare the extent to which sweetpotato augments smallholder’s food availability amongst users and non-users of the Triple S technology ,2. To assess the values which motivate use and uptake of the Triple S technology by smallholder farmers,1. To compare the Knowledge, Attitudes and Perceptions towards the Triple S technology by users and non-users of the technology ,Overall objective: To assess the contribution of the ‘Triple S’ technology on farmers food security in the northern and eastern regions of Uganda.,
Uganda 2024-07-26 15:54:12 2027-07-26 Agricultural Sciences Non-Clinical Trial Degree Award
Adam Lichtenheld
ID: UNCST-2024-R004326
Re:Build – Building Business and Social Networks to Strengthen Refugee Economic and Social Integration
REFNo: SS2803ES

The effect of the intervention on approaches of collaboration and information sharing,The effect of the intervention on psychological and social dimensions for each individual,The effect of the intervention on business outcomes (profit, savings, business growth),The effect of the intervention on network constellations in participants’ egocentric business networks,1. How can interventions support the development of business networks for refugees and nationals in urban markets of developing countries? ,
USA 2024-07-26 15:50:47 2027-07-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
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