Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
WATAKA WILLIES
ID:
HUMAN RESOURCE PRACTICES AND EMPLOYEE TURNOVER IN CITY COUNCILS OF MBALE AND JINJA, EASTERN UGANDA
REFNo: SS2476ES

iv) To establish the effects of employee motivation on employees’ turnover in City Councils of Mbale and Jinja.,iii) To examine the effects of employee health and safety on employees’ turnover in City Councils of Mbale and Jinja.,ii) To establish the effects of employee career growth management on employees’ turnover in City Councils of Mbale and Jinja.,i) To determine the effects of employee reward management on employees’ turnover in City Councils of Mbale and Jinja.,The purpose is to assess how Human Resource Practices have influenced employees’ turnover in City Councils in Eastern Uganda.,
Uganda 2024-05-30 10:41:59 2027-05-30 Social Science and Humanities Non-Clinical Trial Degree Award
Denis Byarugaba Karuhize
ID: UNCST-2023-R006496
Severe acute respiratory infections (SARI) surveillance in hospitalized patients in Uganda
REFNo: HS4166ES

i) To better understand SARI etiology (influenza and other respiratory viruses), severity and risk factors among hospitalized patients with SARI from all age groups
ii) Contribute to Uganda’s and global response and management of SARI
iii) Contribute to international capabilities and collaboration to integrate clinical virological and genomic influenza and other respiratory pathogens surveillance data through the WHO Global Influenza Surveillance and Response System (GISRS) to support intervention and better SARI management and response including influenza vaccine selection, vaccine escape as well other respiratory virus vaccines
iv) Support international alert and response system for emerging strains of pandemic potential

Uganda 2024-05-29 9:45:45 2027-05-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
Secondary use of Uganda Population-based HIV Impact Assessment (UPHIA) samples and associated data for micronutrient surveillance
REFNo: HS4333ES

2. Assess for associations between micronutrient status with HIV status and related indicators using 2020 - 2021 UPHIA metadata,1. Determine national and sub-national prevalence estimates for MND using 2020 - 2021 UPHIA samples,
Uganda 2024-05-29 9:42:49 2027-05-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sherifah Nabikande
ID: UNCST-2022-R009631
Uptake of HIV prevention interventions among adolescent girls and young women in slum settings in Kampala district, Uganda
REFNo: HS4015ES

3) To explore the barriers and facilitators of condom use, HIV testing and Pre-exposure prophylaxis as HIV prevention interventions among AGYW in slum settings in Kampala district, Uganda,2) To determine the factors associated with condom use, HIV testing and Pre-exposure prophylaxis as HIV prevention interventions among AGYW in slum settings in Kampala district, Uganda,1) To determine the proportion of AGYW who use condoms, HIV testing and Pre-exposure prophylaxis as HIV prevention interventions in slum settings in Kampala district, Uganda,To determine the uptake of condoms, HIV testing and Pre-exposure prophylaxis as HIV prevention interventions and factors associated among AGYW in slum settings in Kampala district, Uganda ,
Uganda 2024-05-29 9:40:25 2027-05-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Adoke Yeka
ID: UNCST-2021-R004300
A randomized, open-label, multicenter study to compare efficacy, safety and tolerability of KLU156 with Coartem® in the treatment of uncomplicated Plasmodium falciparum malaria in adults and children ≥ 5 kg body weight followed by an Extension phase with repeated KLU156 treatment.
REFNo: HS3732ES

This study aims to confirm the efficacy, safety and tolerability of KLU156, a fixed dose combination of ganaplacide (KAF156) and a solid dispersion formulation of lumefantrine (lumefantrine-SDF), when administered once daily for three days in adults and children ≥ 5 kg body weight and ≥ 2 months of age suffering from uncomplicated P.Falciparum malaria (with or without other plasmodium spp. co-infection). In the Extension phase, the safety, tolerability and efficacy of repeated treatment with KLU156 will be assessed for a maximum of two years in patients who did not experience early treatment failure(ETF), who did not experience any study treatment-related SAE (Serious Adverse Event) previously and who gave informed consent to participate in the Extension phase.
Uganda 2024-05-29 9:37:35 2027-05-29 Medical and Health Sciences Clinical Trial Non-degree Award
Christine kisubi Esther
ID:
ENVIRONMENTAL JUSTICE IN UGANDA’S OIL AND GAS UPSTREAM SUB-SECTOR DECISION-MAKING
REFNo: SS2634ES

To critically examine the legal frameworks and their implementation concerning environmental justice and community participation in decision-making processes within Uganda\'s oil and gas upstream sub-sector.,
Uganda 2024-05-27 9:01:35 2027-05-27 Social Science and Humanities Non-Clinical Trial Degree Award
Nakacwa Patricia Florence
ID: UNCST-2024-R004518
Student\'s Academic Resilience and Competence Based Curriculum: A case study of Secondary Schools in Mukono and Kayunga District.
REFNo: SS2605ES

iv. To evaluate the moderating influence of emotional intelligence on the relationship between academic resilience and competency-based learning in secondary schools in Mukono and Kayunga districts.,iii. To analyze the effect of academic coordination on competency-based learning in secondary schools in Mukono and Kayunga districts.,ii.To examine the relationship between academic confidence and competency-based learning in secondary schools in Mukono and Kayunga districts.,i.To assess the relationship between academic commitment and competency-based learning in secondary schools in Mukono and Kayunga districts.,The study intends to examine the relationship between academic resilience and competency-based learning to develop a model to support quality education in secondary schools in Uganda.,
Uganda 2024-05-27 9:00:16 2027-05-27 Social Science and Humanities Non-Clinical Trial Degree Award
HELLEN NAIGAGA
ID:
PHENOLOGY MONITORING AND SEASONAL WEATHER FORECASTING IN RELATION TO FARM MANAGEMENT IN UGANDA
REFNo: NS770ES

• To establish local knowledge on abrupt changes in plant phenological patterns • To assess how the use of phenological changes by farmers in weather forecasting impacts on farming activities and farm productivity • To examine the plant compounds and weather parameters which trigger Plant phenological changes • To develop strategies for linking local knowledge and scientific knowledge for future weather forecasting • To predict future weather changes based on plant phenological changes
Uganda 2024-05-27 8:58:04 2027-05-27 Natural Sciences Non-Clinical Trial Degree Award
FREDRICK MAKUMBI
ID:
Post-Phase II Yellow Fever Preventive Mass Vaccination Campaign Coverage Survey in Uganda
REFNo: HS4258ES

To explore individual and health system related factors influencing the non-receipt of yellow fever preventive mass vaccination campaign.,To identify the adverse effects following immunization (AEFI) during the yellow fever preventive mass vaccination campaign.,To assess factors associated with yellow fever preventive mass vaccination campaign uptake.,To determine the reach of the vaccination program and for each of the interventions like IEC, by age, residence (rural/urban), education, wealth, disability status and refugee status.,To measure post-campaign immunization coverage of yellow fever for persons aged 1 to 60 years old within the 6 phase II regions.,The main objective of this survey is to evaluate program performance by coverage, the reach of the program interventions of the yellow fever, and assess the equity of the program to ensure no one is left behind, and validate administrative data coverage at different levels; to further inform the implementation of the vaccination campaign, and provide evidence in each of the 6 phase-II regions (sub-national levels) in Uganda about population vaccination against yellow fever for persons aged 1 to 60 years.,
Uganda 2024-05-27 8:56:24 2027-05-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jacqueline Kyosiimire-Lugemwa
ID: UNCST-2022-R005393
Epigenetic modifications in HIV-1 accessory and regulatory genes, Host genes and differential protein expression among LTNP and Rapid progressors from a Ugandan Cohort
REFNo: HS4047ES

Aim 1. Identify the differential expression of Epigenetic signatures of HIV-1 accessory and regulatory genes DNA methylation among African pediatric LTNP and Rapid progressors Aim 2. Identify the differential expression of Epigenetic signatures of the host genome DNA methylation among African pediatric LTNP and Rapid progressors. Aim 3. Identify the differential expression of plasma proteomic signatures among African pediatric LTNP and Rapid progressors. Aim 4. Establish protein-protein interactions and metabolite interaction networks among African pediatric LTNP and Rapid progressors.
Uganda 2024-05-23 14:57:54 2027-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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