Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
Search By Approval Date:
Clear Filter Total: 5,299
Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Timothy Kiyemba
ID:
Protocol for conducting the beneficiary survey for the USAID Defeat TB project.
REFNo: HS1518ES

The purpose of this beneficiary survey is to assess the results of project implementation with regard to health workers, TB patients and the general community after 3 years of activity implementation in Kampala, Wakiso and Mukono districts.
 Uganda 2021-07-26 2024-07-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Brenda  Boonabaana
ID:
Developing and displacing the 21st century city: mapping the spatial strategies and impacts of global retail investment
REFNo: SS916ES

1.To understand the geographic contexts of global retail capital investment; 2. To trace and understand its geographic transformations; 3. To understand and create grounded and sustainable responses.
Uganda 2021-07-26 2024-07-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Samuel Kabwigu
ID:
ENHANCING UNDERSTANDING OF ADOLESCENT PREGNANCY IN UGANDA: TOWARDS FUTURE IMPLEMENTATION
REFNo: HS859ES

1. Examine how familial relationships influence adolescent pregnancy in Luuka district.
2. Explore factors in the community, (such as ICTS, policies and regulation, or health services) that influence adolescent pregnancies in Luuka District.
3. Assess ways of enhancing familial relationships as a meditative approach that will reduce rates of adolescent pregnancies in Luuka district.

 Uganda 2021-07-23 2024-07-23 Medical and Health Sciences Non-Clinical Trial Degree Award
Rottenberg Esther Sophia
ID:
Making evidence on antimicrobial resistance: a historical and ethnographic study across the UK and Uganda
REFNo: SS622ES

To show how evidence on antimicrobial resistance is produced with the help of a model.
2) To understand how the context of Hoima shapes the production of knowledge on antimicrobial resistance.
3) To investigate the negotiations taking place within the context of a transnational, interdisciplinary research collaboration.
Germany 2021-07-22 2024-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
Jonathan Kajjimu
ID: UNCST-2021-R013696
 MATERNITY CARE FOR WOMEN REFUGEES FROM NAKIVALE REFUGEE RESETTLEMENT: A NEEDS ASSESSMENT
REFNo: SS874ES

1. To determine the socio-demographic characteristics of pregnant refugee women and recently delivered refugee mothers from Nakivale refugee settlement. 2. To describe the experiences of pre-pregnancy, pregnancy, childbirth, postnatal periods, and maternity services available to refugee pregnant women and newly delivered refugee mothers from Nakivale. 3. To identify gaps in maternity care delivered to refugee pregnant women and newly delivered refugee mothers from Nakivale refugee settlement. 4. To acquire opinions of maternity services providers, and refugee pregnant women, and newly delivered refugee mothers from Nakivale refugee settlement on how to improve the refugee pregnancy outcomes.
Uganda 2021-07-22 2024-07-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Katherine Fiorillo Fiorillo
ID:
Measuring Women's Empowerment in Agroforestry Activities in Northern Uganda
REFNo: SS799ES

Research Questions:

● What is the baseline level of women’s empowerment in agroforestry in the project target area?
● How can project activities better address issues of women’s empowerment in agroforestry in the target area?
The main objectives of this research study, listed above, are to understand the baseline level of women’s empowerment and how the project can better respond to these issues. The baseline will be used to both inform and to monitor the project progress towards women’s empowerment. A strong evidence base will allow Kijani to adapt programming to better meet the needs of the community. Qualitative protocols will ensure that the community’s needs and values are being expressed fully in the research process.

USA 2021-07-22 2024-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
Alex Bakenga
ID: UNCST-2021-R014039
 Outcomes of treatment with ADT and chemotherapy in patients with metastatic prostate cancer at the Uganda cancer institute
REFNo: HS1542ES

Objective 1: To describe the biochemical response (TPSA) of patients with metastatic prostate cancer treated with ADT and chemotherapy at the Uganda cancer institute. Objective 2: To determine the 1, 3 and 5-year survival among patients with metastatic prostate cancer treated with ADT and chemotherapy at the Uganda cancer institute. Objective 3: To determine predictors of 1, 3 and 5-year survival among patients with metastatic prostate cancer treated with ADT and chemotherapy at the Uganda cancer institute.
Uganda 2021-07-22 2024-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
SARAH NAWOOVA
ID:
COACHING AND LECTURERS' SUPERVISION SKILLS IN NATIONAL TEACHERS' COLLEGES IN UGANDA
REFNo: SS891ES

1. TO EXAMINE THE RELATIONSHIP BETWEEN COACHING AND LECTURERS' REFLECTIVE QUESTIONING SKILLS.
1.TO EXAMINE THE RELATIONSHIP BETWEEN COACHING AND LECTURERS' OBSERVATION SKILLS.
3.TO EXAMINE THE RELATIONSHIP BETWEEN COACHING AND LECTURERS' FEED BACKING SKILLS.

 Uganda 2021-07-22 2024-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
Benon Asiimwe Byamugisha
ID:
COVID-19 and Antimicrobial Resistance in East Africa: impact and response (CARE)
REFNo: HS1519ES

To establish how community members have received and responded to health messages on COVID-19,To examine how the COVID-19 crisis is affecting patient treatment seeking, drug use, and understanding of illness, and how this is affecting the wider landscape of AMR,To the establish antibiotic provision landscape from the perspective of drug sellers, pharmacists, traditional medicine providers, and formal healthcare workers,To investigate how COVID-19 may be modifying patients’ treatment seeking behaviour, their usage of medicines/ABs and affecting access to and provision of ABs in the therapy landscape in Uganda,
 Uganda 2021-07-22 2024-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mauro Giacomazzi
ID:
Effectiveness of the Whole School System Approach in Fostering Critical Thinking among Learners in Ugandan Secondary Schools
REFNo: SS931ES

Main objective To investigate how the whole school system approach to critical thinking contributes to the development of leaners’ cognitive abilities in Ugandan secondary schools. Specific objectives (i) To establish the meaning of critical thinking in the Ugandan context. (ii) To explore how teachers can improve their teaching and learning through the critical thinking activation approach. (iii) To explore how critical thinking can be appropriately assessed in the Ugandan secondary school context. (iv) To establish the extent to which the whole school system approach contributes to the development of critical thinking abilities of Ugandan secondary school learners. (v) To establish individual, school and home related factors that influence critical thinking abilities of Ugandan secondary school learners. (vi) To explore the strategies that Ugandan secondary school teachers use in preparing and delivering critical thinking augmented lessons.
 Italy 2021-07-22 2024-07-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Robert Opika Opoka
ID: UNCST-2021-R014036
 The role of prolonged exposure to parasitemia in the high morbidity in children with Sickle cell anaemia in Uganda
REFNo: HS1496ES

Primary Aims
1. To determine the rate of parasite clearance during artesunate therapy in children with sickle cell anaemia compared to children without SCA.
We hypothesize that children with SCA will experience parasite clearance half-life times exceeding the WHO-defined standard of 5 hours when treated with artemisinins for P. falciparum malaria, whereas children without SCA will not experience this delayed parasite clearance.

2. To determine the association between parasite clearance rate and risk of vaso-occlusive crisis, severe anaemia, and any hospitalisation in children with SCA.
We hypothesize that prolonged parasite clearance will correlate with increased risk of SCA-related sequelae.

3. To determine the association between kidney and splenic function and parasite clearance half-life during artesunate treatment for malaria.
We hypothesize that impaired renal function (estimated creatinine clearance) and splenic function (presence of Howell-Jolly bodies) will correlate with increased parasite clearance half-life.

Secondary Aims
1. To determine the incidence of treatment failure (new clinical malaria within a 28-day follow-up period after microscopy-confirmed parasite clearance) after artemisinin combination therapy for malaria
2. To detect and measure the prevalence of parasite genetic markers of artemisinin resistance in Jinja

 Uganda 2021-07-21 2024-07-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
James Nyonyintono Mwangwa
ID: UNCST-2023-R005636
 Feasibility of Use of the PATH bCPAP Kit including Oxygen Blenders in a Neonatal Population in Uganda
REFNo: HS650ES

Primary Objectives: 1. To assess the operational feasibility of using the PATH bCPAP kit including, when appropriate, in-line oxygen blending on neonatal patients. 2. To assess the usability and acceptability of the PATH bCPAP kit with oxygen blenders by healthcare workers. Secondary Objective: 1. To report clinical characteristics, demographics and outcomes of patients treated with the PATH bCPAP kit and blenders in a newborn care unit in rural Uganda.
 Uganda 2021-07-19 2024-07-19 Medical and Health Sciences Non-degree Award
Esther Buregyeya
ID: UNCST-2020-R014116
 Using a behavioural approach to design an antimicrobial stewardship intervention in healthcare facilities in Kampala, Mukono and Luwero Districts, Uganda
REFNo: HS1303ES

1. To explore the barriers to and facilitators for rational use of antibiotics and setting up AMS programs in HCFs in Uganda.
2. To develop, pilot an AMS behavioural intervention and assess its acceptability, feasibility and effect to foster appropriate antibiotic prescription in HCFs in Uganda.
3. To assess the cost of the intervention in fostering rational use of antibiotics in Uganda.

 Uganda 2021-07-16 2024-07-16 Medical and Health Sciences Non-degree Award
Shevin  Jacob Thomas
ID:
AN OBSERVATIONAL STUDY TO ASSESS THE UTILITY OF BEDSIDE ULTRASOUND SCAN IN SEPSIS TREATMENT AMONG HOSPITALIZED ADULTS IN UGANDA
REFNo: HS1499ES

General objective: To describe the potential utility of bedside ultrasound scanning in evaluating adult patients with suspected sepsis admitted to hospitals in Uganda Specific objectives: 1. Estimate the proportion of patients admitted to the medical emergency unit with suspected sepsis who have ultrasound findings consistent with intravascular fluid depletion. 2. Estimate the proportion of patients admitted to the medical emergency unit with suspected sepsis who have ultrasound findings suggestive of intolerance to high volume intravenous fluid. 3. Estimate the proportion of patients admitted to the medical emergency unit with suspected sepsis who have ultrasound findings that identify a potential source of infection. 4. Determine the feasibility of delivering POCUS to evaluate non-pregnant adult patients with sepsis by clinicians who are not specialized in radiology.
USA 2021-07-16 2024-07-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Conrad Muzoora Kihembe
ID: UNCST-2019-R001432
 Determination of Adequate TUberculosis Regimen in Adults and adolescents hospitalised with HIV-associated severe immune suppression (Acronym: DATURA).
REFNo: HS1487ES

Primary objective: To estimate the impact of an intensified initial phase of tuberculosis (TB) treatment on mortality at 48 weeks among HIV-infected adults and adolescents hospitalised for TB with CD4 ≤ 100 cells/μL in comparison with the standard TB regimen. Secondary objectives: To estimate the impact of an intensified initial phase of TB treatment, in comparison with the standard TB regimen, on: ¥ Mortality at weeks 8 and 24 ¥ Adverse events, including: - All grade 3-4 events - Selected grade 2 events of interest - Drug-related adverse events - AIDS defining illnesses - Paradoxical TB-associated immune reconstitution inflammatory syndrome (IRIS) ¥ TB treatment success ¥ TB recurrence ¥ Antiretroviral treatment (ART) response in terms of virological success and immunological response ¥ Adherence to TB treatment and ART ¥ Peak plasma concentrations of rifampicin and isoniazid (and its N-acetyl-metabolite) at day 3, day 7 and week. ¥ Plasma concentrations of efavirenz and dolutegravir at week 4 (i.e. 2 weeks after the onset of ART)
Uganda 2021-07-16 2024-07-16 Medical and Health Sciences Clinical Trial Non-degree Award
Davis Ntulume Roland
ID:
A Cross Sectional Study on Exploring the Lifestyle of Makerere University Staff With an Aim of developing a Bespoke Healthy Living Program for people in Academia
REFNo: HS1500ES

Our main goal is to identify and understand the key factors that attribute a typical working day of Makerere University and inhibitors of following a heathy living programme and use this feedback
10
to design a contextually appropriate and bespoke programme for adoption in the field of academia and other sectors at large. This will be achieved in the following sub aims:
1. To establish the dietary and physical activity patterns of overweight and obese staff at Makerere University College of Health Sciences staff.
2. To support overweight and obese individuals to adopt an energy restricted diet and weekly physical exercise while establishing the behavioural and social determinants of compliance to the programme.
3. To establish the effect of change on food and activity body weight and health status and recommend a bespoke healthy living programme that puts into consideration the routine, perceptions and inhibitors to living a healthy lifestyle that works for Academic staff nationwide.
 Uganda 2021-07-16 2024-07-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jude Ssempebwa
ID:
COVID-19 and the Youth Question in Africa: Piloting a Vertically Integrated Social Accountability and Advocacy Framework in the IGAD Region (COYOQA)
REFNo: SS921ES

1. To carry out a comprehensive gender analysis of the current social mobilization of youth in informing, co-designing and supporting COVID-19 pandemic emergency preparedness and response, capacity, key gaps and support needs among IGAD Member States (Ethiopia, Kenya and Uganda).
2. To build the capacity of male and female Youth Volunteers for Behavior Change (YOV4BC) in emergency preparedness, response (disaster risk reduction and management) and building resilience to impacts of COVID-19 so that they are well informed, resourced and educated about COVID-19 and its prevention measures.
3. To partner with the youth to take action within their communities through developing and institutionalizing a standardized and harmonized COVID-19 Vertically Integrated Social Accountability and Advocacy Framework for monitoring the IGAD Regional Response Strategy(IRRS) for COVID-19 Pandemic in Kenya, Uganda and Ethiopia.
4. To investigate and track gender differentiated sectoral socio-economic impacts of COVID-19 on youth and their communities and document community perceptions and response strategies.
5. To facilitate meaningful policy engagement between male and female youth and policy makers through enhanced national, sub-national and regional knowledge sharing platforms.

 Uganda 2021-07-16 2024-07-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
Roselline Achola
ID:
Decision making about Family Planning use by refugee and host populations in Adjumani district, Uganda
REFNo: SS809ES

1.To explore decision making processes for FP use by refugee and host population in Adjumani district
2.To establish factors associated with FP use by women and men in the refugee and host populations in Adjumani
3.To develop and evaluate an intervention to increase FP use by refugee and host populations

Uganda 2021-07-15 2024-07-15 Social Science and Humanities Non-Clinical Trial Degree Award
Richard Munana
ID:
Chronic Kidney Disease among Patients with Diabetes and Hypertension in Nakaseke District Rural Uganda: Assessing Patient Characteristics and the Diagnostic Performance of Saliva Urea Nitrogen Strips in Chronic Kidney Disease Diagnosis When Combined with a Chronic Kidney Disease Case Finding Questionnaire and Machine Learning.
REFNo: HS1387ES

1) To determine the diagnostic performance of Saliva Urea Nitrogen (SUN) strips when combined with a chronic kidney disease case-finding questionnaires and machine learning in the diagnosis of chronic kidney diseases among patients with diabetes and or hypertension in Nakaseke district, rural Uganda. 2)To establish a Chronic Kidney Disease patients’ cohort based in the Rural Uganda Non-Communicable Disease (RUNCD) Cohort in Nakaseke, Uganda.
 Uganda 2021-07-15 2024-07-15 Medical and Health Sciences Non-Clinical Trial Degree Award
Betty OKOT
ID: UNCST-2021-R013938
 Echoes of Antiquity in Acholiland: The Return to Te-Kwaro (Tradition) after the Civil War in Northern Uganda: RefNo:GUREC-2021-57
REFNo: SS833ES

ii. Highlight how memories, practices and unwritten laws reinforce land rights through links and attachment to the past actively conveyed in return migrations; ,3.Examine the roles and disputed effectiveness of traditional chiefs as latter-day custodians of traditional laws in modern times.,1. Recapture and retell the past through specific stories of return to abandoned homesteads ,
 Uganda 2021-07-15 2024-07-15 Social Science and Humanities Non-Clinical Trial Non-degree Award
View Sort By:

"A prosperous Science and Technology Led Ugandan Society."

NRIMS