Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Paul Mwambu
ID:
Adoption of Technological Innovations: A Case Study on the Single Spine Agricultural Extension System among farmer groups in Uganda
REFNo: SS1058ES

1. General Objective: The general objective of this study is to analyze adoption of technological innovations under the single spine agricultural extension system among farmer groups in Kiryandongo and Rukungiri Districts of Ugand,Specific Objective 4: To assess whether the single spine agricultural extension methods affect the adoption of agricultural technological innovations among smallholder farmer groups in Kiryandongo and Rukungiri Districts of Uganda.,specific Objective 3: To examine how the single spine agricultural extension system policy environment facilitates adoption of agricultural technological innovations among smallholder farmer groups.,Specific Objective 2: To analyze how the single spine agricultural extension system management capacities have affected adoption of agricultural technological innovations among smallholder farmer groups under the sin-gle spine agricultural extension systems. ,Specific Objective 1: To analyze how the single spine agricultural extension system governance structures have affected adoption of agricultural technological innovations among smallholder farmer groups. ,
Uganda 2022-01-12 2025-01-12 Social Science and Humanities Non-Clinical Trial Degree Award
Maria NAKACHWA
ID:
Mobile Telephone Communication and Utilization of Antenatal Care Services During Pregnancy. A Case Study of Kyotera and Rakai Districts- Uganda
REFNo: HS1957ES

d. To develop a model for the prediction of ANC uptake when mobile telephone communication is used.,c. To evaluate effects of patient factors in the utilization of antenatal care services among expectant mothers in Kyotera and Rakai Districts , Uganda.,b. To assess patient factors influencing mobile telephone communication among expectant mothers in Kyotera and Rakai Districts, Uganda.,a. To examine effects of mobile telephone communication on the utilization of antenatal care services among expectant mothers in Kyotera and Rakai Districts, Uganda.,
Uganda 2022-01-12 2025-01-12 Medical and Health Sciences Clinical Trial Degree Award
Corinne Kendall
ID:
Using vulture movement patterns in Queen Elizabeth National Park to understand and address poisoning and poaching activities
REFNo: NS311ES

Overall goal: To understand and address the main threats to vultures (and carnivores) in Queen Elizabeth National Park
Objective: Use data from tagged vultures to assess vulture population status and threats, identify and respond to poisoning (and other) incidents and use this information to improve law enforcement and conservation management strategies, and develop appropriate human-wildlife conflict mitigation tools.

Output 1 – Establish a real-time monitoring system by tagging vultures in QENP

Activities
1. Trap and deploy four 70g solar-powered satellite units on White-backed vultures.
2. Analyze data from tagged vultures to find indicators of poaching activities
3. Identify mortality alerts form tagged birds to locate poisoning incidents
4. Provide regular, relevant information to key partners, WCS and UWA, to integrate within existing anti-poaching operations and ensure poisoning events are rapidly discovered and addressed.

Output 2 – Assessment of population status of vultures in QENP
Activities
1. Conduct annual roadside surveys of vultures and other scavenging raptors to understand abundance of birds in QENP, and compared with other similar well-studied sites
2. Use findings from vulture movement studies to inform roadside survey efforts, so that surveys can focus on suitable habitat
3. Use findings from tagged vultures to identify nesting areas and possibly colonies
4. Use population trend change over time to inform long-term success of the conservation management strategies developed from this project


Output 3 – Assessment of threats to vultures in QENP
Activities
1. Take blood samples from vultures to assess the risk of lead exposure in QENP vulture populations and look for seasonal variation in lead levels that may relate to legal and illegal hunting.
2. Collect and map information on mortality events of tagged birds, including the frequency, location and reason for mortality to identify hotspots and main threats
3. Synthesize information with other important overlapping research, such as from collared lion monitoring and known depredation events

Output 4 – Build the capacity of rangers to rapidly respond to poisoning events.
Activities
1. Train 20 rangers in proper protocols for collecting samples at poisoning event to gather appropriate evidence so that perpetrators may be found as well as in proper carcass disposal methods to reduce secondary contamination.
2. Train 20 rangers on how to rehabilitate any sick or injured vultures found at these events and how to release them back into the wild





USA 2022-01-10 2025-01-10 Natural Sciences Non-Clinical Trial Non-degree Award
Andrew Semulimi Weil Matabi
ID: UNCST-2021-R013568
Electrocardiographic patterns among survivors of COVID-19
REFNo: HS1974ES

To determine the factors associated with ECG abnormalities among survivors of COVID-19.,To determine the prevalence of ECG abnormalities among survivors of COVID-19.,To describe ECG patterns among survivors of COVID-19 survivors at Mulago National Specialized Hospital, Kampala, Uganda.,
Uganda 2022-01-10 2025-01-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Peter Kisaakye
ID:
Health, educational and life experiences of young people in refugee settings in Uganda
REFNo: SS1130ES

1) To determine the prevalence of physical, emotional and sexual violence against children in refugee settings in Uganda;
2) To identify the risk and protective factors for physical, emotional and sexual violence against children in refugee settings in the two countries;
3) To determine the health and social consequences associated with violence against children in refugee settings in the two countries;
4) To determine the level of knowledge and utilization of medical, psychosocial, legal, and protective services available for children who have experienced sexual, emotional and physical violence in refugee settings in the two countries; and
5) To make recommendations to relevant government and non-governmental organizations on developing, improving and enhancing prevention and response strategies to address violence against children in refugee settings.

Uganda 2022-01-10 2025-01-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Rebecca Thornton
ID:
Solid Foundations and the Transition to Post-Primary School
REFNo: SS359ES

This proposed study will: 1. extend a longitudinal dataset of students who were participants in a randomised literacy intervention during grades 1-4, as they transition out of primary school and into their adolescence years; 2. measure the effects of foundational literacy skills in primary school – due to the intervention – on primary school completion, secondary school enrolment, and learning outcomes (also measure labor market participation, aspirations, motivation, and other measures of well-being); 3. compare the differential effects of two versions of delivery of the literacy program (a full-cost version and a lower-cost version) to estimate the differences in cost- effectiveness; and 4. compare two levels of exposure to the program (one year vs. four years) to estimate the differences in cost-effectiveness. The project will follow 5,348 students in two cohorts to grades 6/7.
USA 2022-01-07 2025-01-07 Social Science and Humanities Non-degree Award
DAVIS KIBIRIGE
ID:
Optimising screening, diagnosis, and management of diabetes mellitus in an adult Ugandan population with newly diagnosed tuberculosis: The Tuberculosis And DIabetes Comorbidity (TADIC) study.
REFNo: HS1707ES

1. To determine the true burden and clinical predictors of DM and prediabetes in patients with newly diagnosed TB using five diabetes screening tests.
2. To evaluate the performance of three tests (FBG, laboratory derived HbA1c and POC HbA1c) in diagnosing DM and prediabetes in patients with newly diagnosed TB in comparison to the OGTT as the gold standard screening test.
3. To define the phenotypic profile of patients with newly diagnosed TB and confirmed DM and prediabetes.

Uganda 2022-01-07 2025-01-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joseph Ochieng
ID:
Ethical, Legal and Social Issues Associated with Return of Results During Genetics and Genomics Testing in Uganda
REFNo: SS875ES

1. To explore stakeholders’ perceptions of whether results of genetics and genomics testing should be shared with participants and patients
2. To explore stakeholders' perception why results of genetics and genomic testing should be shared or not.
3. For stakeholders who believe results should be shared, to explore views on how results of genetics and genomics testing can be appropriately shared
4. To assess the implications for return of genetics and genomics testing results

Uganda 2022-01-06 2025-01-06 Social Science and Humanities Non-Clinical Trial Degree Award
Leticia Rwakijuma Komba
ID:
Predictors of Research Productivity of Academic Staff in Kyambogo University, Uganda
REFNo: SS742ES

i. To establish whether ascriptive factors predict the research productivity of academic staff of KyU.
ii. To find out whether individual factors predict the research productivity of academic staff of KyU.
iii. To establish whether leadership factors predict the research productivity of academic staff of KyU.
iv. To find out whether institutional factors predict the research productivity of academic staff of KyU.

Uganda 2022-01-06 2025-01-06 Social Science and Humanities Degree Award
Tayebwa Bamwenda James
ID: UNCST-2021-R012825
MOTIVATION FOR CHOICE OF PROGRAM OF STUDY AMONG UNDERGRADUATE STUDENTS JOINING MAKERERE UNIVERSITY
REFNo: SS1020ES

1. To explore the intrinsic factors that motivate students’ choice of a program of study for
higher education in Uganda.
2. To explore the extrinsic factors that motivate students’ choice of program for higher
education in Uganda.
3. To explore the non-motivational but influential factors for students’ choices of programs of
study for higher education in Uganda
Uganda 2022-01-06 2025-01-06 Social Science and Humanities Non-Clinical Trial Degree Award
Carmen  Logie
ID: UNCST-2021-R013185
Tushirikiane4MH: Mental health literacy and mental health promotion with urban refugee youth in Kampala, Uganda
REFNo: SS1021ES

Our specific objectives are to: 1. Explore linkages between social, environmental, and resource scarcity stressors and mental wellbeing; 2. Identify protective factors, coping strategies, and aspirations for collective and individual wellbeing; and 3. Develop, adapt and test mental health interventions and their combination – including the World Health Organization’s Psychological First Aid (PFA) and Group Management Plus, mental health literacy and PFA, and virtual reality approaches to self-compassion and stigma reduction – with and for urban refugee youth in Kampala.
Canada 2022-01-06 2025-01-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
Julie Jarland
ID:
Global Justice in the Shadow of the International Criminal Court
REFNo: SS1061ES

Studying the relationship between the ICC and domestic and local justice processes,Studying the direct and indirect impact of the International Criminal Court (ICC),
Norway 2022-01-06 2025-01-06 Social Science and Humanities Non-Clinical Trial Degree Award
Annet Kajura Mugisha
ID:
An Information Communications Technology enabled model to enhance Active Teaching and Learning strategy in Teacher Training Institutions in Uganda
REFNo: SS1139ES

To evaluate the usefulness, usability and sustainability of the designed ICT model to enhance active teaching and learning strategy in Teacher Training Institutions in Uganda,To design an ICT enabled model that may enhance Active Teaching and Learning strategy in Teacher Training Institutions in Uganda,To examine the extent to teaching which adaptable ICT strategies influence teaching and learning strategy in Teacher Training Institutions in Uganda. ,This study seeks to demonstrate the use of an ICT enabled model to enhance Active Teaching and Learning strategy in Teacher Training Institutions in Uganda.,
Uganda 2022-01-06 2025-01-06 Social Science and Humanities Non-Clinical Trial Degree Award
Kobusingye Doreen Nancy Nancy
ID: UNCST-2021-R012649
Preventive legal empowerment: Early alert and action to strengthen rights in the context of land-based investments
REFNo: SS1115ES

Objectives

The general objective is to explore how preventive legal empowerment support and conflict resolution strategies can help rural communities in Uganda ensure that their land rights are respected, that their communities do not suffer the negative impacts of land-based investments (in particular increased displacement, injustice, environmental degradation, impoverishment, and human rights abuses), and that they can play a more proactive role in democratic, inclusive governance of land and land-based investments.

The specific objectives include the following:

● Provide proactive legal and technical support to communities facing potential land conflicts, and, by doing so, reduce the severity, intensity, and negative impacts of those conflicts.

● Drawing on that legal support, provide evidence on the success of preventive legal empowerment approaches for defending the land rights of communities the context of land- based investments.

● Based on via the early warning hotlines and rapid response mechanisms, gather data on the type and kind of land-based investments being developed in rural and peri-urban areas, including how the investments are approved, who within government approved them, whether the community was properly consulted and gave FPIC, whether the community concluded an agreement with the investor, what benefits, if any, such agreement provides, how the government agencies involved interacted with the community, as well as the effectiveness of community responses to these investments, including in the context of investor-community negotiations.

● Analyse and disseminate this data to inform national and international policy and establish safeguards and protocols that better protect and preserve community and resource rights.

● Throughout project implementation, identify and provide tailored technical and legal empowerment support to women, youth and indigenous community leaders, including to support them in playing a leadership role as land rights defenders, advancing an approach to address social differentiation based on gender transformation and intersectionality.

Uganda 2022-01-06 2025-01-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
Karen Marcours
ID: UNCST-2021-R011626
Adoption of Household and landscape level impacts of Biofortified crops in Uganda
REFNo: A171ES

The study aims to collect 10-year follow-up data to construct a national-level panel of bean and sweet potato producers in Uganda, to study the adoption and disadoption dynamics of different varieties and the relationship with virus-resistance, farm structure and landscape level outcomes. This will aim to inform the design of a possible follow-up data collection efforts (later in 2021) to analyze the nutritional-related gains from biofortification.
The study further aims to test various data collection methods for community-level information, with the objective of optimizing survey design of community-level instruments, applicable in a wide range of future studies to analyze the reach of agricultural innovations and their implications.

Belgium 2022-01-06 2025-01-06 Agricultural Sciences Non-Clinical Trial Non-degree Award
Assumpta Nakintu Maria
ID:
OTITIS MEDIA WITH EFFUSION AND ITS ASSOCIATED FACTORS AMONG PATIENTS WITH CEREBRAL PALSY BETWEEN 2 TO 18 YEARS AT MULAGO AND KAWEMPE NATIONAL REFERRAL HOSPITALS REC NO.2021-180
REFNo: HS1958ES

To determine the burden and factors associated with otitis media with effusion among patients between 2 to 18 years with cerebral palsy at Mulago and Kawempe National Referral Hospitals,To determine the factors associated with otitis media with effusion among patients beween 2 to 18 years with cerebral palsy at Mulago and Kawempe National Referral Hospitals,To determine the prevalence of otitis media with effusion among patients between 2 to 18 years with cerebral palsy at Mulago and Kawempe National Referral Hospitals,
Uganda 2022-01-05 2025-01-05 Medical and Health Sciences Non-Clinical Trial Degree Award
Emmy Okello
ID: UNCST-2020-R009792
A Long-Term Follow-up Study for Patients Who Participated in the GOAL Trial (GOAL-Post)
REFNo: HS1975ES

Primary Objective: To assess whether children who completed the GOAL trial and now have normal
echocardiograms have the same risk for progression as a new group of age/sex matched controls who
have a normal echocardiogram at study entry.
Secondary Objectives: To determine the 5-year rates of RHD progression among children with
persistent latent RHD who receive every-4-week BPG prophylaxis (durability of the intervention to
prevent RHD progression).
Tertiary Objective: To create a biobank that will support future research on RHD genetic
predisposition.
Uganda 2022-01-05 2025-01-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
FREDDIE SSENGOOBA Peter
ID: UNCST-2021-R011834
An Assessment of Health Facility and District Autonomy, Income, and Expenditures in Uganda
REFNo: HS1985ES

To document and assess the de jure versus de facto autonomy levels for fiscal and operational decision making; de jure versus de facto use, reporting and accounting mechanisms of available resources; and the purchasing arrangements and expenditure reporting mechanisms that have been put in place for COVID-19 related activities and services at the district and facility levels in Uganda.
Uganda 2022-01-05 2025-01-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Andrew Mujugira
ID: UNCST-2019-R000871
Implementation science research on PrEP delivery and costing within harm reduction services for people who use drugs in Uganda.
REFNo: HS1744ES

Aim 1. To compare PrEP uptake, retention, and adherence when PrEP is delivered through
community-based NSP versus facility-based MAT to PWUD.
Brief approach. We will integrate PrEP delivery into the first-ever MAT program in Kampala
(facility-based model) and a community-based NSP program. We will work with
community advocates for PWUD to recruit 150 people per program and compare uptake
of PrEP, retention, and objective measures of PrEP adherence (plasma tenofovir) during
one year of follow-up.
Aim 1a. To measure the impact of knowledge gained from training peers of PWUD on PrEP.
Brief approach. We will train up to 50 health care providers of PWUD on PrEP service
delivery using the national curriculum on PrEP services delivery. We will administer a
quantitative assessment of PrEP knowledge and experiences with service provision at
three time points: 1. Before the training (Baseline survey), 2. immediately after training
(Post training survey), and 3. ~3 months post training (Exit survey).
Aim 2. To estimate the programmatic costs and conduct budget impact analysis for
integrating PrEP into MAT and NSP programs.
Brief approach. We will conduct costing and budget impact analyses, including estimating
costs incurred for people who elect to not use PrEP, to guide approaches for intervention
scale-up
Uganda 2022-01-03 2025-01-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Halid Kirunda
ID:
Evaluation of efficacy and safety of AMITRANOR® in tick control in Uganda
REFNo: HS1947ES

1. Determine the in vitro efficacy of AMITRANOR® on the main cattle ticks in Uganda.
2. Determine the “knockdown” effect of AMITRANOR® on ticks on cattle.
3. Enumerate any adverse effects of AMITRANOR® among experimental cattle.

Uganda 2022-01-03 2025-01-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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