Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Kenneth Odur
ID:
Assessing Community Perceptions on the State of Nutrition in Uganda. Focus Group Discussions and Key Informant Interviews in Lira District.
REFNo: SS1385ES

To impact malnutrition on the national and international level through research and dissemination.,To equip youth ambassadors in Ayami with knowledge and experience conducting qualitative research through focus groups and key informant interviews.,To equip community members in Ayami sub county with increased knowledge of the causes and consequences of malnutrition, as well as positive behaviors and resources to address malnutrition.,To assess community knowledge, attitudes, and beliefs on malnutrition and current malnutrition interventions.,To qualitatively assess implementation of the Uganda Nutrition Action Plan in Ayami sub county, Lira District.,
 Uganda 2022-09-06 14:29:01 2025-09-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
Charles Kiyaga
ID:
A Validation Study to Compare the Performance of Gazelle Point-of-Care Device with Isoelectric Focusing and Capillary Electrophoresis in testing for Sickle Cell Disease in Uganda
REFNo: HS2319ES

c) To assess the usability and operational characteristics of Gazelle, including the ease of use, technical complexity and inter-reader variability.,b) To evaluate foetal haemoglobin (HbF) quantitation in SCD patients on hydroxyurea treatment, as compared to standard methods, in Uganda.,a) To determine the sensitivity and specificity of Gazelle in comparison to the standard tests used for the diagnosis of SCD.,
 Uganda 2022-09-06 14:24:20 2025-09-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
David Musoke
ID:
Enhancing the capacity of Community Health Workers on epidemic and pandemic preparedness and response in Wakiso district, Uganda: impact evaluation and dissemination
REFNo: HS2349ES

Overall objective To carry out an impact evaluation of a recent project that enhanced the capacity of Village Health Teams (VHTs) on epidemic and pandemic preparedness and response (including COVID-19) in Wakiso district so as to generate information to enhance scale-up of interventions as well as inform future related activities. Specific objectives 1. To explore how the performance of VHTs in relation to epidemic / pandemic preparedness and response including COVID-19 was affected by the training. 2. To explore other effects of the training on epidemic / pandemic preparedness and response including COVID-19 to VHTs and their communities.
Uganda 2022-09-06 14:22:51 2025-09-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 Estimating the real-world effectiveness and determinants of effectiveness China Manufactured and other COVID-19 vaccines in Uganda
REFNo: HS2422ES

To determine the overall and product-specific rate of breakthrough infections (laboratory-confirmed SARS-CoV-2) among adult Ugandans vaccinated with China manufactured and other COVID-19 vaccines in Uganda,To estimate COVID-19 vaccine effectiveness (CVE) for more severe outcomes (e.g., ICU admission, or in-hospital mortality) and its determinants in among adults diagnosed with COVID-19 in Uganda,To determine the overall and product-specific effectiveness of China manufactured and other COVID 19 vaccines against symptomatic COVID-19 disease among adults diagnosed with COVID 19 in Uganda,
 Uganda 2022-09-06 14:21:36 2025-09-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Fred Wauyo
ID: UNCST-2022-R010247
 HOLISTIC MODEL FOR PREDICTING USER ADOPTION MECHANISM OF MOBILE APPLICATIONS FOR BUSINESS GROWTH IN MEDIUM ENTERPRISES: THE CASE OF KAMPALA CITY COUNCIL AUTHORITY
REFNo: SIR136ES

4. To propose a holistic model for predicting user adoption of mobile applications at KCCA,3. To test and validate the proposed model at KCCA,2. To determine factors that influence users intentions to adopt mobile applications at KCCA,1. To assess the existing mobile applications user adoption at KCCA.,The main research objective of this thesis is to “explain the mobile application adoption mechanism in the market and also build a holistic model that predicts user’s adoption of the third party mobile applications at KCCA.,
 Uganda 2022-09-06 14:20:08 2025-09-06 Engineering and Technology Non-Clinical Trial Degree Award
Roy Mayega William
ID: UNCST-2022-R010983
 Composition of honey sold on the Kampala market and its glycemic response among diabetic patients.
REFNo: HS2286ES

1) To characterise the carbohydrate composition of locally produced honey on the Kampala market.
2) To determine the organic composition of locally produced honey on the Kampala market.
3) To assess the Glycemic index of diabetic patients subjected to locally produced honey.


 Uganda 2022-09-06 14:18:12 2025-09-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Gorretti Nassali
ID:
A PHASE III, RANDOMIZED, OPEN-LABEL, MULTICENTER STUDY EVALUATING THE EFFICACY AND SAFETY OF ADJUVANT GIREDESTRANT COMPARED WITH PHYSICIAN'S CHOICE OF ADJUVANT ENDOCRINE MONOTHERAPY IN PATIENTS WITH ESTROGEN RECEPTOR?POSITIVE, HER2 NEGATIVE EARLY BREAST CANCER
REFNo: HS2133ES

Primary objective:
To demonstrate superiority of giredestrant over the control treatment
Secondary objectives:
1. To evaluate the efficacy of giredestrant compared with TPC
2. To evaluate the safety of giredestrant compared with TPC
3. To characterize giredestrant pharrmacokinetics (PK)
4. To evaluate health status utility scores of participants treated with giredestrant compared with TPC
5. To evaluate the efficacy of giredestrant compared with TPC
6. To evaluate the tolerability of giredestrant compared with TPC
7. To identify and/or evaluate biomarkers that are predictive of response to giredestrant
Uganda 2022-09-06 14:14:37 2025-09-06 Medical and Health Sciences Clinical Trial Non-degree Award
Mary Gorreti Nabbosa
ID:
Application of the IFLA code of ethics for librarians in selected academic universities in Uganda
REFNo: SS1372ES

i. To identify the services offered by Kyambogo University and Uganda Christian University libraries.

ii. To examine the ethical practices of librarians in Kyambogo University and Uganda Christian University libraries.

iii. To investigate whether Kyambogo University and Uganda Christian university librarians have applied the IFLA code of ethics in library and information service delivery.

iv. To determine the challenges faced by librarians Kyambogo University and Uganda Christian University libraries when applying the IFLA code of ethics in the library and information service delivery.
 Uganda 2022-08-30 17:24:16 2025-08-30 Social Science and Humanities Non-Clinical Trial Degree Award
JAMES MULEME
ID: UNCST-2021-R012263
 Safe Food and Water: Promoting the protection and safety of household and community water and food resources
REFNo: HS2311ES

1. Using the Trials of Improved Practices (TIPS) technique to co-design water and food protection solutions that reduce the risk of bat contamination, using locally available resources 2. Using the Trials of Improved Practices (TIPS) technique to implement an SBC intervention to improve community knowledge and behaviours relating to food and water safety and understanding of the need to protect food and water sources (focused on bat-related risks) 3. Demonstrate feasibility and effectiveness of locally resourced interventions (benefits and costs) that protect water and food sources from bat contamination. This will contribute to the adoption of sanitation and hygiene measures and practices to ensure safe water and food
 Uganda 2022-08-30 16:42:20 2025-08-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Charles  Katulamu
ID:
Morals, Beliefs, and the Law Disconnected from Reality: Uncovering the Abortion Realm in Kampala, Uganda.
REFNo: SS1412ES

1. To understand the drivers of pregnancy termination.

2. To investigate the determinants of access to safe abortion care.

3. To find out how women decide to terminate a pregnancy.

4. To investigate women navigate the law, cultural stigma, and religious expectations before, during, and post-abortion.

5. To understand how abortion care providers make decisions on who receives the care.

6. To find out the challenges abortion care providers face, how they address them, and their recommendations towards the health and wellness of women in Uganda.
 Uganda 2022-08-30 10:47:16 2025-08-30 Social Science and Humanities Non-Clinical Trial Degree Award
Samuel Biraro
ID:
Evaluation of Integrated Child Health Days in Select Districts in Uganda
REFNo: HS2410ES

Main objective
To evaluate the effectiveness of integrated child health days in Uganda to reach children who are un-immunized and under-immunized and suggest recommendations for improvement of the ICHD service delivery program in three districts (Bukedea, Kayunga, and Rakai) in Uganda.

Specific Objectives
1. To identify and estimate the proportion of children under 5 years of age, who attend and do not attend CHDs and describe key factors affecting attendance in selected district(s).
2. To understand the knowledge, attitudes, practices (KAP), motivators, and barriers for the implementation of CHDs by health system staff and community members (i.e., Health managers, healthcare workers, village health workers, and local community leaders) to inform improvement in service delivery.
3. To describe the systematic approach, best practices, enablers, and barriers during CHDs according to the five pillars of immunization strategy (service delivery; planning, management, and finance; data and surveillance; cold chain and vaccine management; advocacy, communication, and social mobilization) and suggest recommendations that be used to improve coverage, quality, and equity of immunization services during ICHDs.

 Uganda 2022-08-30 10:45:06 2025-08-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Cecilia  Nantume
ID:
Rapid Assessments of Progress: An evaluation of DMPA-SC Self Injection Public Sector Service Delivery in Uganda
REFNo: HS2409ES

To establish clients perceived quality and overall satisfaction with self injection service delivery,To identify client challenges to uptake of DMPA-SC and self injection use ,To assess the extent to which attitudes and behavior of providers and stakeholders accelerate or hinder Self Injection uptake, ,To determine the emerging health system barriers and facilitators that influence Self Injection uptake.,
 Uganda 2022-08-30 10:42:45 2025-08-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Anne Wajja J W
ID: UNCST-2022-R010518
 A multi-country, epidemiologic study to assess the interferon gamma release assay (IGRA) positivity, and to build capacity to conduct a tuberculosis (TB) vaccine efficacy study, in populations with a high TB disease burden
REFNo: HS2371ES

o To describe the proportion of IGRA positivity by site

Secondary objectives:
o To assess the association of age with proportion of IGRA positivity, by site o To describe the overall incidence of suspected and laboratory-confirmed pulmonary TB (disease)

Tertiary objectives o To describe changes in the proportion of IGRA positivity by site
o To describe the association between IGRA interferon gamma (IFN) concentration at screening and progression to pulmonary TB

Uganda 2022-08-30 10:37:18 2025-08-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ramathan Mugalu
ID:
BUSINESS EDUCATION AND PERFORMANCE OF BUSINESS SCHOOLS’ GRADUATES IN SELECTED ORGANIZATIONS IN KAMPALA, UGANDA
REFNo: SS1168ES

The general objective was to examine the influence of business education on the job performance of business schools’ graduate in the selected organisations in Kampala- Uganda.
 Uganda 2022-08-30 10:34:40 2025-08-30 Social Science and Humanities Non-Clinical Trial Degree Award
Losira Nasirumbi
ID: UNCST-2021-R013084
 Intra-household Gender Dynamics in Uptake of Agricultural Technologies for Sustainable Livelihoods in Uganda
REFNo: SS1375ES

1) Understand the dissemination and use of agricultural technologies in selected districts of the Eastern Agro-Ecological Zone of Uganda
2) Analyse the intra-household gender roles and relations related to technology access and sustained use within the institution of the household
3) Quantify the distribution of decision-making power within households and how these influence technology uptake and empowerment among women and youth
 Uganda 2022-08-30 10:32:05 2025-08-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
Bernard Lukuyu Adubwa
ID:
Improving pig productivity and incomes through an environmentally sustainable and gender inclusive integrated intervention package
REFNo: A210ES

1. Piloting and evaluating innovative market arrangements at the level of pig aggregators to strengthen market linkages between them and pig farmers and link the farmers to input and service providers.
2. Implementing and evaluating an integrated package for improving pig productivity and performance comprising pig herd health practices, reproductive management, improved genetics, and better feeding, for farmers participating in the market arrangements and delivered through a digital extension platform

3. Developing, testing and evaluating best-bet interventions for reducing the environmental footprint primarily through waste (manure) management and adaption to heat stress

 Kenya 2022-08-30 10:28:45 2025-08-30 Agricultural Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 ASSESSMENT OF USABILITY OF THE WONDFO HIV SELF-TEST ONE STEP HIV 1/2 WHOLE BLOOD/SERUM/PLASMA TEST BY UNTRAINED USERS
REFNo: HS1878ES

To evaluate the ability to correctly comprehend key messaging from device packaging and labelling, including the Instructions for Use.,The evaluation of untrained users’ and their interaction with the device in terms of effectiveness and efficiency, i.e. successful / unsuccessful completion and difficulty of the critical steps as per the Instructions for Use,To evaluate the ability of untrained users to obtain an accurate HIV test result using the Wondfo HIV Self-Test.,
 Uganda 2022-08-30 10:24:48 2025-08-30 Medical and Health Sciences Clinical Trial Non-degree Award
Gerald Zirintunda
ID:
Assessment of the ethnoveterinary practices, knowledge and attitudes for the control of chicken helminths in Soroti district
REFNo: A220ES

1. To document the ethnoveterinary knowledge, attitudes and practices for chicken disease control in farming communities of Soroti district.
2. To determine the efficacy of crude extracts from selected natural products used in control of helminths in chicken.
3. To determine the safety of crude extracts from selected medicinal plants used in control of helminths in chicken.
4. To determine the phytochemical composition and the bioactive ingredients in the most potent extracts.

Uganda 2022-08-25 12:19:28 2025-08-25 Agricultural Sciences Non-Clinical Trial Degree Award
Elizeus Rutebemberwa
ID: UNCST-2022-R009070
 Learning, Acting and Building for Rehabilitation in Health Systems (ReLAB-HS) Policy and Prioritization of Rehabilitation in the Ugandan Health System
REFNo: HS2400ES

The aim of this project is to answer the following research questions: “What political and bureaucratic factors shape prioritization and implementation of policies that advance rehabilitation in Uganda?”
Uganda 2022-08-25 12:16:34 2025-08-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan Nassiwa
ID:
Enteral Nutrition and Burn Wound Recovery of Paediatric Patients: A Case of Kiruddu National Referral Hospital
REFNo: HS2388ES

General Objective:
To determine the association between enteral nutrition and burn wound recovery of paediatric patients at Kiruddu National Referral Hospital (KNRH) in Buziga, Kampala.
Specific objectives:
To examine the relationship between normal oral diet and burn wound recovery of paediatric patients in KNRH in Buziga, Kampala.
To investigate how use of liquid supplements contributes to burn wound recovery of paediatric patients in KNRH in Buziga, Kampala.
To establish the association between tube feeding and burn wound recovery of paediatric patients in KNRH in Buziga, Kampala.
 Uganda 2022-08-25 12:14:05 2025-08-25 Medical and Health Sciences Non-Clinical Trial Degree Award
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