Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
JOSELYN RWEBEMBERA
ID: UNCST-2021-R013915
A Non-Inferiority Trial of Stopping Penicillin in Early Rheumatic Heart Disease: GOAL-Stop
REFNo: HS6744ES

To explore if risk of progression differs between children who initially received 2 years of oral SAP as compared to 2 years of intramuscular SAP during the GOALIE trial. ,To determine in children with previously diagnosed mild RHD and echocardiographic stabilization after receiving SAP for at least 2 years, if stopping secondary antibiotic prophylaxis (SAP) is non-inferior to continuing SAP in preventing progression over the next 2 years. ,To determine in children with previously diagnosed mild RHD and echocardiographic normalization after receiving SAP for at least 2 years, if stopping SAP is non-inferior to continuing SAP for preventing progression over the next 2 years. ,To determine in children with previously diagnosed mild RHD and echocardiographic normalization or echocardiographic stability after receiving SAP for at least 2 years, if stopping SAP is non-inferior to continuing SAP for preventing progression by 4 years (2 years after SAP discontinuation). ,
Uganda 2025-12-18 18:47:07 2028-12-18 Medical and Health Sciences Clinical Trial Non-degree Award
Asiimire Arinaitwe
ID: UNCST-2023-R008026
ICT Paradigm and Academic Management Efficiency in Private Universities In Uganda. A Case Study of Uganda Christian University
REFNo: SS4598ES

1. To explore the perceptions of academic staffs on the role of ICT in improving academic management efficiency at Uganda Christian University 2. To investigate the processes through which ICT is effectively used to facilitate academic decision-making at Uganda Christian University. 3. To explore how University academic managers use ICT tools in the planning and utilization of institutional academic resources at Uganda Christian University. 4. To examine the application of ICT to support academic transparency and accountability at Uganda Christian University.
Uganda 2025-12-18 18:42:45 2028-12-18 Social Science and Humanities Non-Clinical Trial Degree Award
Pauline Byakika-Kibwika
ID: UNCST-2019-R001206
A phase III, multi-country, randomized, placebo-controlled, double-blinded adaptive platform trial to assess the efficacy and safety of treatments for participants with Mpox virus disease
REFNo: HS6913ES

To evaluate the safety and efficacy, as assessed by mortality, hospitalization, complications, duration of symptoms of IP + SOC compared to placebo + SOC in participants with Mpox.,The primary objective is to evaluate the clinical efficacy, as assessed by time to lesion(s) resolution, of IP + Standard of Care (SOC) compared to placebo + SOC for participants with Mpox.,
Uganda 2025-12-18 18:34:19 2028-12-18 Medical and Health Sciences Clinical Trial Non-degree Award
Norah Babirye
ID: UNCST-2024-R015349
Understanding Food Environment Determinants of Indigenous Fruit and Vegetable Consumption and Co-creating Acceptable Recipes with Overweight and Obese Adults in Wakiso District, Uganda
REFNo: A671ES

1. To analyze the food environment and pschological determinants that influence the
consumption of indigenous vegetables and fruits among overweight and obese adults.
2. a) To collaboratively develop recipes incorporating indigenous vegetables and fruits
with overweight and obese adults.
b) To assess the acceptability of the co-created recipes among overweight and obese
adults.
Uganda 2025-12-18 18:04:57 2028-12-18 Agricultural Sciences Non-Clinical Trial Degree Award
Samuel kirimunda
ID: UNCST-2021-R012738
Using Drug Resistance Candidate Gene mutations as markers of Ancestor strains and Genome fitness in Whole Genome Sequence transmission Clusters of Ugandan TB and TB-HIV patients
REFNo: HS6805ES

Main objective To determine whether mutations in drug-resistance candidate genes are associated with TB and TB-HIV transmission clusters among Uganda MTBC isolates. Specific objectives 1.To develop and curate a TB and TB-HIV WGS database for Mtb strains of Ugandan origin 2. To identify ancestry strains among transmission clusters of M. tuberculosis 3. To identify Drug resistance candidate gene markers in Ugandan Whole Genome Sequences 4.To identify drug resistance candidate gene mutations associated with ancestor genomes 5.To identify drug resistance candidate gene mutations associated with TB/HIV+ ancestor genomes
Uganda 2025-12-18 18:01:28 2028-12-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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